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• Protein Classification

• Types (3 types)
• Classes (11 classes)
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• Species (538 species)
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1s3e » Monoamine oxidase B, monomer

• Type: 1. Transmembrane (3 classes)
• Class: 1.2. Alpha-helical bitopic (42 superfamilies)
• Superfamily: 1.2.33. Transmembrane proteins with NAD(P)-binding Rossmann-fold domains (2 families)
• Family: 1.2.33.02. Flavin containing amine oxidoreductase (8 proteins)
• Species: Homo sapiens (443 proteins)
• Localization: Mitochondrial outer membrane (20 proteins)

1s3e » Monoamine oxidase B, monomer
Hydrophobic Thickness	7.3 ± 0.6 Å
Tilt Angle	37 ± 1°
ΔGtransfer	-14.2 kcal/mol
Links to 1s3e	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	cytoplasmic
Resolution	1.60 Å
Other PDB entries of this protein	1gos, 1oj9, 1oja, 1ojc, 1ojd, 1s2q, 1s2y, 1s3b, 2bk3, 2bk4, 2bk5, 2byb, 2c64, 2c65, 2c66, 2c67, 2c70, 2c72, 2c73, 2c75, 2c76, 2v5z, 2v60, 2v61, 2vrl, 2vrm, 2vz2, 2xcg, 2xfn, 2xfo, 2xfp, 2xfq, 2xfu, 3po7, 3zyx, 4a79, 4a7a
Number of TM subunits	2

Comments on 1s3e » Monoamine oxidase B, monomer
Monomer, homo- or heterodimer. Enzymatically active as monomer. Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAO-B preferentially degrades benzylamine and phenylethylamine.

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA