PDB ID or protein name

1s3e » Monoamine oxidase B, monomer

1s3e » Monoamine oxidase B, monomer
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Topology in Mitochondrial outer membrane
Topologyintermembrane space side
cytoplasmic side
1s3e » Monoamine oxidase B, monomer
Hydrophobic Thickness 7.3 ± 0.6 Å
Tilt Angle 37 ± 1°
ΔGtransfer -14.2 kcal/mol
Links to 1s3e PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology cytoplasmic
Resolution 1.60 Å
Other PDB entries representing this structure 1gos, 1oj9, 1oja, 1ojc, 1ojd, 1s2q, 1s2y, 1s3b, 2bk3, 2bk4, 2bk5, 2byb, 2c64, 2c65, 2c66, 2c67, 2c70, 2c72, 2c73, 2c75, 2c76, 2v5z, 2v60, 2v61, 2vrl, 2vrm, 2vz2, 2xcg, 2xfo, 2xfp, 2xfq, 2xfu, 3po7, 3zyx, 4a79, 4a7a
Number of TM subunits 2
Comments on 1s3e » Monoamine oxidase B, monomer
Monomer, homo- or heterodimer. Enzymatically active as monomer. Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAO-B preferentially degrades benzylamine and phenylethylamine.