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• Protein Classification

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1sfr » Antigen 85a

• Type: 2. Monotopic/peripheral (4 classes)
• Class: 2.3. Alpha/Beta monotopic/peripheral (33 superfamilies)
• Superfamily: 2.3.06. Alpha/beta-hydrolases (15 families)
• Family: 2.3.06.02. Mycobacterial antigens (4 proteins)
• Species: Mycobacterium tuberculosis (14 proteins)
• Localization: Bacterial Gram-positive outer membrane (7 proteins)

1sfr » Antigen 85a
Depth	2.8 ± 0.8 Å
Tilt Angle	27 ± 9°
ΔGtransfer	-7.5 kcal/mol
Links to 1sfr	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	out
Resolution	2.7 Å
Other PDB entries of this protein	none
Number of subunits	1

Comments on 1sfr » Antigen 85a
Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintaining cell wall integrity.

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University of Michigan, Ann Arbor, MI 48109 USA