PDB ID or protein name

1spf » Pulmonary surfactant-associated protein C

1spf » Pulmonary surfactant-associated protein C
Magnify 1spf » Pulmonary surfactant-associated protein CEnlarged view of image
3D view in Jmol or Webmol

gray dot

Download Coordinates

gray dot

Topology in Secreted
Topologyout side
in side
1spf » Pulmonary surfactant-associated protein C
Hydrophobic Thickness 31.7 ± 3.3 Å
Tilt Angle 21 ± 0°
ΔGtransfer -32.0 kcal/mol
Links to 1spf PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology subunit A (N-terminus in)
Resolution NMR
Other PDB entries representing this structure 2esy
Number of TM Secondary Structures 1
1 transmembrane subunit
A - Tilt: 21° - Segments: 1(10-33)
Experimental Verification for 1spf » Pulmonary surfactant-associated protein C
This peptide forms a hydrophopbic alpha-helix, with a transmembrane orientation (Vandenbussche et al. 1992).
1 reference
Vandenbussche G, Clercx A, Curstedt T, Johansson J, Jornvall H, Ruysschaert JM. 1992. Structure and orientation of the surfactant-associated protein C in a lipid bilayer. Eur J Biochem. 203:201-9. PubMed
Comments on 1spf » Pulmonary surfactant-associated protein C
Structure in chloroform-methanol (2esy is the structure of a shorter analogue in DPC micelles). Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. This is full-length peptide.