PDB ID or protein name

1t5s » Calcium ATPase, E1-ATP state

1t5s » Calcium ATPase, E1-ATP state
Magnify 1t5s » Calcium ATPase, E1-ATP stateEnlarged view of image
3D view in Jmol or Webmol

gray dot

Download Coordinates

gray dot

Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
1t5s » Calcium ATPase, E1-ATP state
Hydrophobic Thickness 29.7 ± 1.6 Å
Tilt Angle 22 ± 1°
ΔGtransfer -58.6 kcal/mol
Links to 1t5s PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology subunit A (N-terminus cytoplasmic)
Resolution 2.60 Å
Other PDB entries representing this structure 3n8g
Number of TM Secondary Structures 10
1 transmembrane subunit
A - Tilt: 22° - Segments: 1(61-77), 2(85-104), 3(259-274), 4(289-306), 5(759-780), 6(789-807), 7(832-852), 8(897-915), 9(932-949), 10(967-986)
Experimental Verification for 1t5s » Calcium ATPase, E1-ATP state
Results are consistent with data about biological activity of ATPase in bilayers of various hydrophobic thicknesses (Cornea and Thomas 1994, Lee 1998).
2 references
Cornea RL, and Thomas DD (1994) Effect of membrane thickness on the molecular dynamics and enzymatic activity of reconstituted Ca-ATPase. Biochemistry 33: 2912-2920. PubMed
Lee AG (1998) How lipids interact with an intrinsic membrane protein: the case of the calcium pump. Biochim. Biophys. Acta 1376: 381-390. PubMed
Comments on 1t5s » Calcium ATPase, E1-ATP state
Related PDB entries represent the same conformational state.