PDB ID or protein name

1tqn » Cytochrome P450 3A4, conformation 1

1tqn » Cytochrome P450 3A4, conformation 1
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
1tqn » Cytochrome P450 3A4, conformation 1
Hydrophobic Thickness 8.7 ± 1.0 Å
Tilt Angle 67 ± 11°
ΔGtransfer -18.5 kcal/mol
Links to 1tqn PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology cytoplasmic
Resolution 2.0 Å
Other PDB entries representing this structure 1w0e, 1w0f, 1w0g, 2j0d, 3ua1, 4d6z, 4d75, 4i3q, 4k9t, 4k9u, 4k9v, 4k9x, 4ny4, 5a1p, 5a1r
Number of TM subunits 1
Experimental Verification for 1tqn » Cytochrome P450 3A4, conformation 1
Crystallization with detergent (CYMAL-6/CHAPS). This cytochrome has a tentative N-terminal TMH, consistent with the calculated orientation.
Comments on 1tqn » Cytochrome P450 3A4, conformation 1
2j0c and 2j0d have the same calculated positions in the membrane as 1tqn, although conformations of some loops in 2j0c are different.