PDB ID or protein name

1tqn » Cytochrome P450 3A4, conformation 1

1tqn » Cytochrome P450 3A4, conformation 1
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
1tqn » Cytochrome P450 3A4, conformation 1
Hydrophobic Thickness 8.7 ± 1.0 Å
Tilt Angle 67 ± 11°
ΔGtransfer -18.5 kcal/mol
Links to 1tqn PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology cytoplasmic
Resolution 2.0 Å
Other PDB entries representing this structure 1w0e, 1w0f, 1w0g, 2j0d, 3ua1, 4d6z, 4d75, 4i3q, 4k9t, 4k9u, 4k9v, 4k9x, 4ny4, 5a1p, 5a1r, 5g5j, 5vcc, 5vcd, 5vce, 5vcg, 6bcz, 6bd5, 6bd6, 6bd7, 6bd8, 6bdi, 6bdk, 6bdm
Number of TM subunits 1
Experimental Verification for 1tqn » Cytochrome P450 3A4, conformation 1
Crystallization with detergent (CYMAL-6/CHAPS). This cytochrome has a tentative N-terminal TMH, consistent with the calculated orientation.
Comments on 1tqn » Cytochrome P450 3A4, conformation 1
2j0c and 2j0d have the same calculated positions in the membrane as 1tqn, although conformations of some loops in 2j0c are different.