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1txa » Toxin B

• Type: 2. Monotopic/peripheral (4 classes)
• Class: 2.2. All beta monotopic/peripheral (57 superfamilies)
• Superfamily: 2.2.39. Snake toxin-like (2 families) 1.C.74 (TCDB)
• Family: 2.2.39.01. Snake venom toxins (15 proteins) C.1.74 (TCDB)
• Species: Ophiophagus hannah (4 proteins)
• Localization: Secreted (681 proteins)

1txa » Toxin B
Depth	2.6 ± 1.5 Å
Tilt Angle	51 ± 16°
ΔGtransfer	-5.6 kcal/mol
Links to 1txa	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	out
Resolution	NMR
Other PDB entries of this protein	1txb
Number of subunits	1

Comments on 1txa » Toxin B
Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to muscular and neuronal (only alpha-7 alpha-8 alpha-9) nicotinic acetylcholine receptors (By similarity).

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA