PDB ID or protein name

1zcd » Sodium/proton antiporter 1 (NhaA)

1zcd » Sodium/proton antiporter 1 (NhaA)
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Topology in Bacterial Gram-negative inner membrane
Topologyout side
in side
1zcd » Sodium/proton antiporter 1 (NhaA)
Hydrophobic Thickness 28.4 ± 1.4 Å
Tilt Angle 2 ± 2°
ΔGtransfer -78.6 kcal/mol
Links to 1zcd PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology subunit A (N-terminus in)
Resolution 3.4 Å
Other PDB entries representing this structure none
Number of TM Secondary Structures 14
1 transmembrane subunit
A - Tilt: 2° - Segments: 1(12-31), 2(59-80), 3(98-116), 4(121-130), 5(134-140), 6(156-174), 7(181-200), 8(206-219), 9(223-236), 10(254-271), 11(291-311), 12(329-336), 13(338-350), 14(358-379)
Experimental Verification for 1zcd » Sodium/proton antiporter 1 (NhaA)
Accessibilities of two residues to paramagnetic quenchers (Hilger et al. 2005) are consistent with locations of the calculated membrane boundaries.
1 reference
Hilger D, Jung H, Padan E, Wegener C, Vogel KP, Steinhoff HJ, and Jeschke G (2005) Assessing oligomerization of membrane proteins by four-pulse DEER: pH-dependent dimerization of NhaA Na+/H+ antiporter of E. coli. Biophys. J. 89: 1328-1338. PubMed
Comments on 1zcd » Sodium/proton antiporter 1 (NhaA)
This protein forms a non-physiological head-to-head dimer.