PDB ID or protein name

1zll » Phospholamban, pentamer

1zll » Phospholamban, pentamer
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
1zll » Phospholamban, pentamer
Hydrophobic Thickness 30.5 ± 1.4 Å
Tilt Angle 0 ± 2°
ΔGtransfer -76.0 kcal/mol
Links to 1zll PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology subunit A (N-terminus cytoplasmic)
Resolution NMR
Other PDB entries representing this structure 1psl, 2hyn, 2kyv
Number of TM Secondary Structures 5
5 transmembrane subunits
A - Tilt: 20° - Segments: 1(28-50)
B - Tilt: 23° - Segments: 1(28-50)
C - Tilt: 21° - Segments: 1(28-50)
D - Tilt: 21° - Segments: 1(28-50)
E - Tilt: 20° - Segments: 1(28-50)
Experimental Verification for 1zll » Phospholamban, pentamer
Average tilt (21°) of TM helices is slightly smaller than estimated by ATR FTIR (28±6°)(Arkin et al. 1995).
1 reference
Arkin IT, Rothman M, Ludlam CFC, Aimoto S, Engelman DM, Rothschild KJ and Smith SO (1995) Structural model of the phospholamban ion channel complex in phospholipids membranes. J. Mol. Biol. 248: 824-834. PubMed
Comments on 1zll » Phospholamban, pentamer
This is structure of full-length peptide in DPC micelles. All models of the pentamer (experimental: 1xnu, 1zll, and 2hyn and theoretical: 1k9n,1pln, 1psl, and 1kch) represent essentially the same structure of transmembrane alpha-bundle, with CA atom rmsd of 1-2 A (1psl was apparently the first model deposited to the PDB). Experimental models of monomeric helix: 1n7l (in detergent),1plp (TFE), 1fjp and 1fjk; 1n7l (detergent, rabbit), 2kb7 (solution + solid state NMR).