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• Protein Classification

• Types (3 types)
• Classes (11 classes)
• Superfamilies (392 superfamilies)
• Families (667 families)
• Species (538 species)
• Localization (24 types)
• All proteins in OPM (2172 proteins)

• Protein Links

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2a65 » Leucine transporter LeuT, outward-facing substrate-bound conformation

• Type: 1. Transmembrane (3 classes)
• Class: 1.1. Alpha-helical polytopic (72 superfamilies)
• Superfamily: 1.1.26. APC (Amino acid-Polyamine-organoCation) superfamily (6 families) 2.A.3 (TCDB)
• Family: 1.1.26.01. Neurotransmitter: sodium symporter (4 proteins) 2.A.22 (TCDB)
• Species: Aquifex aeolicus (10 proteins)
• Localization: Bacterial Gram-negative inner membrane (269 proteins)

2a65 » Leucine transporter LeuT, outward-facing substrate-bound conformation
Hydrophobic Thickness	29.8 ± 0.5 Å
Tilt Angle	0 ± 0°
ΔGtransfer	-157.9 kcal/mol
Links to 2a65	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	subunit A (N-terminus in)
Resolution	1.65 Å
Other PDB entries of this protein	2q6h, 2q72, 2qb4, 2qei, 2qju, 3f3c, 3f3d, 3f3e, 3f48, 3f4i, 3f4j, 3gjc, 3gjd, 3gwu, 3gwv, 3gww, 3mpn, 3mpq, 3qs5, 3qs6, 3tu0, 3usg, 3usi, 3usj, 3usk, 3usl, 3usm, 3uso, 3usp
Number of TM Secondary Structures	28

2 transmembrane subunits
A - Tilt: 4° - Segments: 1(15-35), 2(40-63), 3(89-124), 4(166-184), 5(190-215), 6(241-256), 7(277-298), 8(339-364), 9(378-395), 10(398-425), 11(448-473), 12(483-501)
B - Tilt: 4° - Segments: 1(15-35), 2(40-63), 3(89-124), 4(166-184), 5(190-215), 6(241-256), 7(277-298), 8(339-364), 9(378-395), 10(398-425), 11(448-473), 12(483-501)

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA