- Protein Classification
- Protein Links
 | lumenal side |
| cytoplasmic side |
| 2bdm » Cytochrome P450 2B4, open state 1 | |
|---|---|
| Hydrophobic Thickness | 10.6 ± 1.0 Å |
| Tilt Angle | 48 ± 15° |
| ΔGtransfer | -16.2 kcal/mol |
| Links to 2bdm | PDB Sum, PDB, SCOP, MSD, OCA, MMDB |
| Topology | cytoplasmic |
| Resolution | 2.3 Å |
| Other PDB entries of this protein | none |
| Number of TM subunits | 1 |
| Comments on 2bdm » Cytochrome P450 2B4, open state 1 |
|---|
| This cytochrome forms a nonnative interwinded dimer in crystal. Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it has a unique preference for the 5,6-olefin. |
