PDB ID or protein name

2crd » Charybdotoxin

2crd » Charybdotoxin
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Topology in Secreted
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2crd » Charybdotoxin
Depth 1.1 ± 1.5 Å
Tilt Angle 86 ± 15°
ΔGtransfer -3.2 kcal/mol
Links to 2crd PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology out
Resolution NMR
Other PDB entries representing this structure 1bah
Number of subunits 1
Experimental Verification for 2crd » Charybdotoxin
Experimental membrane bindig affinity is -2.0 kcal/mol (0.2 M KCl) to -3.6 kcal/mol (0.1 M KCl), and up to -8 kcal/mol at lower non-physiological ionic strength (Ben-Tal et al. 1997).
1 reference
Ben-Tal, N., Honig, B., Miller, C., and McLaughlin, S. 1997. Electrostatic binding of proteins to membranes. Theoretical predictions and experimental results with charybdotoxin and phospholipid vesicles. Biophys. J. 73:1717-1727. PubMed
Comments on 2crd » Charybdotoxin
Membrane-binding site participates in association with potassium channel (see structure of the complex, 2a9h).