PDB ID or protein name

2dyr » Mitochondrial cytochrome c oxidase

2dyr » Mitochondrial cytochrome c oxidase
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Topology in Mitochondrial inner membrane
Topologyintermembrane space side
matrix space side
2dyr » Mitochondrial cytochrome c oxidase
Hydrophobic Thickness 28.0 ± 0.6 Å
Tilt Angle 0 ± 0°
ΔGtransfer -198.1 kcal/mol
Links to 2dyr PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology subunit A (N-terminus matrix space)
Resolution 1.80 Å
Other PDB entries representing this structure 1occ, 1oco, 1ocr, 1ocz, 1v54, 1v55, 2dys, 2eij, 2eik, 2eil, 2eim, 2ein, 2occ, 2y69, 2zxw, 3abk, 3abl, 3abm, 3ag1, 3ag2, 3ag3, 3ag4, 3asn, 3aso, 3wg7, 3x2q, 5b1a, 5b1b, 5b3s, 5w97, 5wau, 5x19, 5x1b, 5x1f, 5xdq
Number of TM Secondary Structures 56
20 transmembrane subunits
A - Tilt: 8° - Segments: 1( 18- 39), 2( 56- 78), 3( 99- 117), 4( 142- 162), 5( 186- 211), 6( 231- 255), 7( 271- 291), 8( 304- 325), 9( 336- 360), 10( 372- 393), 11( 409- 429), 12( 452- 472)
B - Tilt: 11° - Segments: 1(27-47), 2(59-77)
C - Tilt: 4° - Segments: 1( 17- 35), 2( 41- 55), 3( 82- 100), 4( 126- 146), 5( 161- 181), 6( 197- 217), 7( 237- 258)
D - Tilt: 36° - Segments: 1(78-99)
G - Tilt: 20° - Segments: 1(16-37)
I - Tilt: 5° - Segments: 1(16-36)
J - Tilt: 29° - Segments: 1(34-54)
K - Tilt: 16° - Segments: 1(14-33)
L - Tilt: 15° - Segments: 1(22-43)
M - Tilt: 22° - Segments: 1(15-36)
N - Tilt: 9° - Segments: 1( 18- 39), 2( 56- 79), 3( 99- 117), 4( 142- 162), 5( 186- 211), 6( 233- 255), 7( 271- 291), 8( 304- 325), 9( 336- 359), 10( 372- 394), 11( 408- 429), 12( 453- 472)
O - Tilt: 11° - Segments: 1(27-47), 2(59-77)
P - Tilt: 4° - Segments: 1(17-35), 2(40-54), 3(82-100), 4(126-145), 5(162-181), 6(197-217), 7(237-258)
Q - Tilt: 37° - Segments: 1(77-99)
T - Tilt: 21° - Segments: 1(16-37)
V - Tilt: 4° - Segments: 1(16-34)
W - Tilt: 28° - Segments: 1(34-54)
X - Tilt: 17° - Segments: 1(14-33)
Y - Tilt: 15° - Segments: 1(22-42)
Z - Tilt: 23° - Segments: 1(15-36)
Experimental Verification for 2dyr » Mitochondrial cytochrome c oxidase
Calculated hydrophobic thickness is about 1.5 Å smaller than from experimental data (Montecucco et al. 1982).
1 reference
Montecucco C, Smith GA, Dabbeni-sala F, Johansson A, Galante YM, and Bisson R (1982) Bilayer thickness and enzymatic activity in the mitochondrial cytochrome c oxidase and ATPase complex. FEBS Lett. 144: 145-148. PubMed