PDB ID or protein name

2h4t » Carnitine O-palmitoyltransferase 2

2h4t » Carnitine O-palmitoyltransferase 2
Magnify 2h4t » Carnitine O-palmitoyltransferase 2Enlarged view of image
3D view in Jmol or Webmol

gray dot

Download Coordinates

gray dot

Topology in Mitochondrial inner membrane
Topologyintermembrane space side
matrix space side
2h4t » Carnitine O-palmitoyltransferase 2
Depth 4.0 ± 1.2 Å
Tilt Angle 67 ± 10°
ΔGtransfer -9.4 kcal/mol
Links to 2h4t PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology matrix space
Resolution 1.9 Å
Other PDB entries representing this structure 2deb, 2fw3, 2fyo, 2rcu, 4ep9, 4eph, 4eyw
Number of subunits 1
Experimental Verification for 2h4t » Carnitine O-palmitoyltransferase 2
This protein can be classified as integral monotopic (Mattevi 2006). Calculated orientation corresponds to membrane-binding mode proposed by Rufer et al. (2006).
2 references
Mattevi A. 2006. A monotopic membrane protein goes solo. Structure. 14: 628-9. PubMed
Rufer AC, Thoma R, Benz J, Stihle M, Gsell B, De Roo E, Banner DW, Mueller F, Chomienne O, Hennig M. 2006. The crystal structure of carnitine palmitoyltransferase 2 and implications for diabetes treatment. Structure. 14: 713-23. PubMed
Comments on 2h4t » Carnitine O-palmitoyltransferase 2
Catalytic activity: Palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.