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• Protein Classification

• Types (3 types)
• Classes (11 classes)
• Superfamilies (392 superfamilies)
• Families (667 families)
• Species (538 species)
• Localization (24 types)
• All proteins in OPM (2172 proteins)

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2h8a » Microsomal glutathione S-transferase 1

• Type: 1. Transmembrane (3 classes)
• Class: 1.1. Alpha-helical polytopic (72 superfamilies)
• Superfamily: 1.1.61. MAPEG (Eicosanoid and Glutathione metabolism proteins) (1 family)
• Family: 1.1.61.01. MAPEG domain (5 proteins)
• Species: Rattus norvegicus (74 proteins)
• Localization: Endoplasmic reticulum membrane (125 proteins)

2h8a » Microsomal glutathione S-transferase 1
Hydrophobic Thickness	29.7 ± 0.7 Å
Tilt Angle	0 ± 1°
ΔGtransfer	-47.7 kcal/mol
Links to 2h8a	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	subunit A (N-terminus lumenal)
Resolution	3.20 Å
Other PDB entries of this protein	none
Number of TM Secondary Structures	12

3 transmembrane subunits
A - Tilt: 20° - Segments: 1(12-32), 2(74-94), 3(101-122), 4(127-146)
B - Tilt: 20° - Segments: 1(12-32), 2(74-94), 3(101-122), 4(127-146)
C - Tilt: 20° - Segments: 1(12-32), 2(74-94), 3(101-122), 4(127-146)

Comments on 2h8a » Microsomal glutathione S-transferase 1
Fold is similar to that in a subdomain of main subunit of cytochrome c oxidase.

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA