2iql » Mu-opioid receptor model (inactive state) with antagonist
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Topology in Eukaryotic plasma membrane
Download Coordinates
Topology in Eukaryotic plasma membrane
 | extracellular side |
| cytoplasmic side |
- Type: 1. Transmembrane (2 classes)
- Class: 1.1. Alpha-helical transmembrane (54 superfamilies)
- Superfamily: 1.1.01. Rhodopsin-like proteins (2 families)
- Family: 1.1.01.02. G-protein coupled receptors (15 proteins)
- Species: Rattus norvegicus (37 proteins)
- Localization: Eukaryotic plasma membrane (195 proteins)
| 2iql » Mu-opioid receptor model (inactive state) with antagonist | |
|---|---|
| Hydrophobic Thickness | 35.0 ± 1.0 Å |
| Tilt Angle | 9 ± 3° |
| ΔGtransfer | -97.7 kcal/mol |
| Links to 2iql | PDB Sum, SCOP, MSD, OCA, MMDB, Dali |
| Topology | subunit A (N-terminus extracellular) |
| Resolution | model Å |
| Related PDB Sum entries | none |
| Number of TM Secondary Structures | 7 |
| 1 transmembrane subunit |
|---|
| A - Tilt: 9° - Segments: 1( 65- 91), 2( 105- 130), 3( 137- 163), 4( 183- 205), 5( 229- 254), 6( 281- 306), 7( 315- 339) |
| 1 reference |
|---|
| Fowler CB, Pogozheva ID, LeVine H 3rd, Mosberg HI. 2004. Refinement of a homology model of the mu-opioid receptor using distance constraints from intrinsic and engineered zinc-binding sites. Biochemistry. 43: 8700-8710. PubMed |
