PDB ID or protein name

2iqr » Melanocortin-4 receptor model (active state) with agonist NDP-MSH

2iqr » Melanocortin-4 receptor model (active state) with agonist NDP-MSH
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Topology in Eukaryotic plasma membrane
Topologyextracellular side
cytoplasmic side
2iqr » Melanocortin-4 receptor model (active state) with agonist NDP-MSH
Hydrophobic Thickness 33.5 ± 2.0 Å
Tilt Angle 24 ± 0°
ΔGtransfer -60.6 kcal/mol
Links to 2iqr PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology subunit A (N-terminus extracellular)
Resolution model Å
Other PDB entries representing this structure none
Number of TM Secondary Structures 7
1 transmembrane subunit
A - Tilt: 23° - Segments: 1(48-67), 2(81-105), 3(121-149), 4(164-187), 5(192-217), 6(244-270), 7(282-304)
1 reference
Pogozheva ID, Chai BX, Lomize AL, Fong TM, Weinberg DH, Nargund RP, Mulholland MW, Gantz I, Mosberg HI. 2005. Interactions of human melanocortin 4 receptor with nonpeptide and peptide agonists. Biochemistry. 44: 11329-11341. PubMed