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• Protein Classification

• Types (3 types)
• Classes (11 classes)
• Superfamilies (393 superfamilies)
• Families (668 families)
• Species (539 species)
• Localization (24 types)
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2j5d » BNip3 transmembrane domain homodimer, second alternative structure

• Type: 1. Transmembrane (3 classes)
• Class: 1.2. Alpha-helical bitopic (42 superfamilies)
• Superfamily: 1.2.21. BNip3 protein family (1 family) 1.A.20 (TCDB)
• Family: 1.2.21.01. BNip3 (BCL2/Adenovirus E1B-interacting protein 3) (3 proteins) 1.A.20 (TCDB)
• Species: Homo sapiens (443 proteins)
• Localization: Mitochondrial outer membrane (20 proteins)

2j5d » BNip3 transmembrane domain homodimer, second alternative structure
Hydrophobic Thickness	30.8 ± 2.5 Å
Tilt Angle	12 ± 0°
ΔGtransfer	-35.8 kcal/mol
Links to 2j5d	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	subunit A (N-terminus cytoplasmic)
Resolution	NMR
Other PDB entries representing this structure	2ka1, 2ka2
Number of TM Secondary Structures	2

2 transmembrane subunits
A - Tilt: 29° - Segments: 1(162-184)
B - Tilt: 20° - Segments: 1(165-184)

Comments on 2j5d » BNip3 transmembrane domain homodimer, second alternative structure
This is structure in bicelle. The dimer is strongly asymmetric, apparently a result of dynamics and insufficient constraints.

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA