PDB ID or protein name

2k1l » Receptor tyrosine kinase EphA1, at pH 6.3

2k1l » Receptor tyrosine kinase EphA1, at pH 6.3
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Topology in Eukaryotic plasma membrane
Topologyextracellular side
cytoplasmic side
2k1l » Receptor tyrosine kinase EphA1, at pH 6.3
Hydrophobic Thickness 28.8 ± 1.2 Å
Tilt Angle 5 ± 3°
ΔGtransfer -42.3 kcal/mol
Links to 2k1l PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology subunit A (N-terminus extracellular)
Resolution NMR
Other PDB entries representing this structure none
Number of TM Secondary Structures 2
2 transmembrane subunits
A - Tilt: 21° - Segments: 1( 547- 566)
B - Tilt: 28° - Segments: 1( 547- 566)
Comments on 2k1l » Receptor tyrosine kinase EphA1, at pH 6.3
This is structure in bicelle at normal pH. At the lower pH, N-terminus of TM helix partly unfolds, however the structure remains essentially the same (rmsd of 2.4 A).