PDB ID or protein name

2k9j » Integrin alpha-IIb, complex with integrin beta-3

2k9j » Integrin alpha-IIb, complex with integrin beta-3
Magnify 2k9j » Integrin alpha-IIb, complex with integrin beta-3Enlarged view of image
3D view in Jmol or Webmol

gray dot

Download Coordinates

gray dot

Topology in Eukaryotic plasma membrane
Topologyextracellular side
cytoplasmic side
2k9j » Integrin alpha-IIb, complex with integrin beta-3
Hydrophobic Thickness 36.4 ± 3.3 Å
Tilt Angle 20 ± 1°
ΔGtransfer -56.4 kcal/mol
Links to 2k9j PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology subunit A (N-terminus extracellular)
Resolution NMR
Other PDB entries of this protein 2k1a, 2knc, 2rmz, 2rn0
Number of TM Secondary Structures 2
2 transmembrane subunits
A - Tilt: 9° - Segments: 1(965-988)
B - Tilt: 33° - Segments: 1(691-718)
Comments on 2k9j » Integrin alpha-IIb, complex with integrin beta-3
This is a heterodimer in bicelle. Related PDB structures are shown for TM domain of integrin beta3 (2k1a is alphaIIb segment in bicelles; 2rmz and 2rn0 are NMR models of beta3 TM segment in bicelles). Structures of C-terminal cytoplasmic domain include partially unfolded conformations in the presence of micelles (2kv9,2l1c,1kup,1kuz,1m8o,1s4x) and folded crystal structures (1mk7,1mk9). Structures of N-terminal extracellular domain - see 3fcs.