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• Protein Classification

• Types (3 types)
• Classes (11 classes)
• Superfamilies (392 superfamilies)
• Families (667 families)
• Species (538 species)
• Localization (24 types)
• All proteins in OPM (2172 proteins)

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2rh1 » Beta-2 adrenergic receptor, inactive state, dimer

• Type: 1. Transmembrane (3 classes)
• Class: 1.1. Alpha-helical polytopic (72 superfamilies)
• Superfamily: 1.1.01. Rhodopsin-like receptors and pumps (4 families) 3.E.1 (TCDB)
• Family: 1.1.01.02. G-protein coupled receptors, family A (47 proteins) 9.A.14 (TCDB)
• Species: Homo sapiens (443 proteins)
• Localization: Eukaryotic plasma membrane (479 proteins)

2rh1 » Beta-2 adrenergic receptor, inactive state, dimer
Hydrophobic Thickness	31.8 ± 0.9 Å
Tilt Angle	0 ± 1°
ΔGtransfer	-143.2 kcal/mol
Links to 2rh1	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	subunit A (N-terminus extracellular)
Resolution	2.4 Å
Other PDB entries of this protein	none
Number of TM Secondary Structures	14

2 transmembrane subunits
C - Tilt: 5° - Segments: 1(31-56), 2(70-92), 3(104-129), 4(150-171), 5(198-220), 6(275-298), 7(306-327)
D - Tilt: 5° - Segments: 1(31-56), 2(70-92), 3(104-129), 4(150-171), 5(198-220), 6(275-298), 7(306-327)

Comments on 2rh1 » Beta-2 adrenergic receptor, inactive state, dimer
2rh1 and 3d4s represent chimera of adrenergic receptor and T4 lysozyme. 2r4r, 2r4s and 3kj6 represent complex with antibodies (not included because the cytoplasmic parts of TM helices and loops are disordered and missing in the crystal structures).

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA