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• Protein Classification

• Types (3 types)
• Classes (11 classes)
• Superfamilies (463 superfamilies)
• Families (861 families)
• Species (719 species)
• Localization (24 types)
• All proteins in OPM (3450 proteins)

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2wsx » L-carnitine/gamma-butyrobetaine antiporter CaiT, open inward-facing conformation

• Type: 1. Transmembrane (3 classes)
• Class: 1.1. Alpha-helical polytopic (106 superfamilies)
• Superfamily: 1.1.026. APC (Amino acid-Polyamine-organoCation) superfamily (8 families) 2.A.3 (TCDB)
• Family: 1.1.26.04. Betaine/carnitine/choline transporters (10 proteins) 2.A.15 (TCDB)
• Species: Escherichia coli (249 proteins)
• Localization: Bacterial Gram-negative inner membrane (465 proteins)

2wsx » L-carnitine/gamma-butyrobetaine antiporter CaiT, open inward-facing conformation
Hydrophobic Thickness	28.6 ± 0.7 Å
Tilt Angle	7 ± 0°
ΔGtransfer	-212.7 kcal/mol
Links to 2wsx	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	subunit A (N-terminus in)
Resolution	3.50 Å
Other PDB entries representing this structure	none
Number of TM Secondary Structures	42

3 transmembrane subunits
A - Tilt: 22° - Segments: 1(12-30), 2(42-67), 3(92-99), 4(102-112), 5(132-142), 6(144-151), 7(187-216), 8(231-277), 9(279-302), 10(312-335), 11(350-369), 12(406-434), 13(446-464), 14(471-491)
C - Tilt: 13° - Segments: 1(12-30), 2(42-67), 3(92-99), 4(102-112), 5(132-142), 6(144-151), 7(187-216), 8(232-277), 9(279-302), 10(312-335), 11(350-369), 12(406-434), 13(446-464), 14(471-491)
B - Tilt: 13° - Segments: 1(12-30), 2(42-67), 3(92-99), 4(102-112), 5(132-142), 6(144-151), 7(187-216), 8(232-277), 9(279-302), 10(312-335), 11(350-369), 12(406-434), 13(446-464), 14(471-491)

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA