PDB ID or protein name

2zbd » Calcium ATPase, E1P-ADP state

2zbd » Calcium ATPase, E1P-ADP state
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
2zbd » Calcium ATPase, E1P-ADP state
Hydrophobic Thickness 31.8 ± 1.4 Å
Tilt Angle 22 ± 2°
ΔGtransfer -70.6 kcal/mol
Links to 2zbd PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology subunit A (N-terminus cytoplasmic)
Resolution 2.40 Å
Other PDB entries representing this structure none
Number of TM Secondary Structures 10
1 transmembrane subunit
A - Tilt: 22° - Segments: 1(60-78), 2(84-104), 3(259-281), 4(288-310), 5(759-781), 6(789-807), 7(832-854), 8(895-916), 9(933-950), 10(964-987)
Experimental Verification for 2zbd » Calcium ATPase, E1P-ADP state
Results are consistent with data about biological activity of ATPase in bilayers of various hydrophobic thicknesses (Cornea and Thomas 1994, Lee 1998).
2 references
Cornea RL, and Thomas DD (1994) Effect of membrane thickness on the molecular dynamics and enzymatic activity of reconstituted Ca-ATPase. Biochemistry 33: 2912-2920. PubMed
Lee AG (1998) How lipids interact with an intrinsic membrane protein: the case of the calcium pump. Biochim. Biophys. Acta 1376: 381-390. PubMed
Comments on 2zbd » Calcium ATPase, E1P-ADP state
Similar conformational states are indicated as related PDB entries