PDB ID or protein name

4qkm » M2 proton channel of Influenza A, open state, ligand-free

4qkm » M2 proton channel of Influenza A, open state, ligand-free
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Topology in Viral membrane
Topologyout side
in side
4qkm » M2 proton channel of Influenza A, open state, ligand-free
Hydrophobic Thickness 28.4 ± 1.7 Å
Tilt Angle 0 ± 0°
ΔGtransfer -55.4 kcal/mol
Links to 4qkm PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology subunit A (N-terminus out)
Resolution 1.10 Å
Other PDB entries representing this structure 3bkd, 4qk7, 4qkc, 4qkl
Number of TM Secondary Structures 4
4 transmembrane subunits
A - Tilt: 31° - Segments: 1(25-44)
B - Tilt: 31° - Segments: 1(25-44)
C - Tilt: 31° - Segments: 1(25-44)
D - Tilt: 31° - Segments: 1(25-44)
Comments on 4qkm » M2 proton channel of Influenza A, open state, ligand-free
Two crystal structures (3bkd and 3c9j) are close to each other (CA atom rmsd of 1.1 A) but strongly differ from NMR structure, 2rlf (rmsd of 3.8-3.9 A). 3c9j is similar to amantadine-bound solid state NMR model 2h95 (rmsd of 2.4A).