PDB ID or protein name

5fn4 » Gamma-secretase complex, structure 5

5fn4 » Gamma-secretase complex, structure 5
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
5fn4 » Gamma-secretase complex, structure 5
Hydrophobic Thickness 30.4 ± 0.9 Å
Tilt Angle 7 ± 0°
ΔGtransfer -143.1 kcal/mol
Links to 5fn4 PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology subunit A (N-terminus lumenal)
Resolution 4.0 Å
Other PDB entries representing this structure none
Number of TM Secondary Structures 18
5 transmembrane subunits
A - Tilt: 12° - Segments: 1( 669- 690)
B - Tilt: 16° - Segments: 1( 85- 102), 2( 168- 189), 3( 195- 213), 4( 220- 240), 5( 243- 261), 6( 383- 399), 7( 403- 421), 8( 436- 461)
C - Tilt: 5° - Segments: 1( 4- 26), 2( 32- 59), 3( 70- 91), 4( 118- 139), 5( 157- 179), 6( 187- 207), 7( 210- 231)
D - Tilt: 4° - Segments: 1( 58- 79)
G - Tilt: 39° - Segments: 1( 1- 22)