PDB ID or protein name

5fn5 » Gamma-secretase complex, structure 6

5fn5 » Gamma-secretase complex, structure 6
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
5fn5 » Gamma-secretase complex, structure 6
Hydrophobic Thickness 30.2 ± 1.2 Å
Tilt Angle 2 ± 1°
ΔGtransfer -134.8 kcal/mol
Links to 5fn5 PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology subunit A (N-terminus lumenal)
Resolution 4.3 Å
Other PDB entries representing this structure none
Number of TM Secondary Structures 17
4 transmembrane subunits
A - Tilt: 12° - Segments: 1( 669- 690)
B - Tilt: 6° - Segments: 1( 85- 103), 2( 171- 189), 3( 195- 214), 4( 221- 240), 5( 244- 259), 6( 381- 398), 7( 404- 421), 8( 435- 458)
C - Tilt: 5° - Segments: 1( 4- 26), 2( 32- 56), 3( 70- 91), 4( 118- 139), 5( 157- 179), 6( 186- 206), 7( 211- 231)
D - Tilt: 10° - Segments: 1( 58- 79)