• Type: Monotopic/peripheral (4 classes)
• Class: All beta monotopic/peripheral (60 superfamilies)
• Superfamily: Peptidase clan AA (2 families) CL0129
• Family: Eukaryotic aspartyl protease (5 proteins) PF00026 IPR033121 PDBsum
• Species: Homo sapiens (2659 proteins)
• Localization: Lysosome membrane (102 proteins)

1lyb >> Cathepsin D
Hydrophobic Thickness or Depth	7.0 Å
Tilt Angle	87°
ΔGtransfer	-11.2 kcal/mol
Links to 1lyb	PDB Sum, PDB, MSD, MMDB
Topology	lumenal side
Resolution	2.5
Primary PDB represention	1lyb
Other PDB entries representing this structure	1lya (2.5), 1lyw (2.5)
Number of TM secondary structures	0
Membranome
Uniprot	CATD_HUMAN

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Download OPM File: 1lyb.pdb

PDB Sum, PDB

Topology in Lysosome membrane

	lumenal side
	cytoplasmic side

3D view in GLMol | LiteMol | Jmol | iCn3D

Comments: Lysosomal membrane-associated protease. Consists of a light chain and a heavy chain.