• Type: Transmembrane (3 classes)
• Class: Bitopic proteins (67 superfamilies)
• Superfamily: Cytochrome P450 (1 families) PF00067
• Family: Cytochrome P450 (122 proteins) PF00067 IPR001128 PDBsum
• Species: Homo sapiens (2659 proteins)
• Localization: Endoplasmic reticulum membrane (548 proteins)

1tqn >> Cytochrome P450 3A4, structure 1
Hydrophobic Thickness or Depth	8.7 Å
Tilt Angle	67°
ΔGtransfer	-18.5 kcal/mol
Links to 1tqn	PDB Sum, PDB, MSD, MMDB
Topology	cytoplasmic side
Resolution	2.05
Primary PDB represention	1tqn
Other PDB entries representing this structure	1w0e (2.8), 1w0f (2.65), 1w0g (2.73), 2j0d (2.75), 3ua1 (2.15), 4d6z (1.93), 4d75 (2.25), 4i3q (2.6), 4k9t (2.5), 4k9u (2.85), 4k9v (2.6), 4k9x (2.76), 4ny4 (2.95), 5a1p (2.5), 5a1r (2.45), 5g5j (2.6), 5vcc (1.7), 5vcd (1.95), 5vce (2.2), 5vcg (2.2), 6bcz (2.23), 6bcz (2.23), 6bd5 (2.5), 6bd6 (2.5), 6bd7 (2.42), 6bd8 (2.38), 6bdi (2.57), 6bdk (2.67), 6bdm (2.6), 6da2 (2.65), 6da3 (2.37), 6da5 (2.25), 6da8 (2.8), 6daa (2.15), 6dac (2.55), 6dag (2.8), 6daj (2.45), 6dal (2.65), 6ma6 (2.18), 6ma7 (2.09), 6ma8 (1.83), 6oo9 (2.25), 6ooa (2.52), 6oob (2.2), 7ks8 (2.5), 7kvp (2.75), 8ewd (2.2), 8ewe (2.3), 8ewl (2.35), 8ewm (2.3), 8ewn (2.1), 8ewp (2.4), 8ewq (2.25), 8ewr (2.2), 8ews (2.15), 8exb (2.05)
Number of TM secondary structures	0
Membranome
Uniprot	CP3A4_HUMAN

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Download OPM File: 1tqn.pdb

PDB Sum, PDB

Topology in Endoplasmic reticulum membrane

	lumenal side
	cytoplasmic side

3D view in GLMol | LiteMol | Jmol | iCn3D

Comments: 2j0c and 2j0d have the same calculated positions in the membrane as 1tqn, although conformations of some loops in 2j0c are different.