1tqn >> Cytochrome P450 3A4, structure 1
Hydrophobic Thickness or Depth8.7 Å
Tilt Angle67°
ΔGtransfer-18.5 kcal/mol
Links to 1tqnPDB Sum, PDB, MSD, MMDB
Topologycytoplasmic side
Resolution2.05
Primary PDB represention1tqn
Other PDB entries representing this structure1w0e (2.8), 1w0f (2.65), 1w0g (2.73), 2j0d (2.75), 3ua1 (2.15), 4d6z (1.93), 4d75 (2.25), 4i3q (2.6), 4k9t (2.5), 4k9u (2.85), 4k9v (2.6), 4k9x (2.76), 4ny4 (2.95), 5a1p (2.5), 5a1r (2.45), 5g5j (2.6), 5vcc (1.7), 5vcd (1.95), 5vce (2.2), 5vcg (2.2), 6bcz (2.23), 6bcz (2.23), 6bd5 (2.5), 6bd6 (2.5), 6bd7 (2.42), 6bd8 (2.38), 6bdi (2.57), 6bdk (2.67), 6bdm (2.6), 6da2 (2.65), 6da3 (2.37), 6da5 (2.25), 6da8 (2.8), 6daa (2.15), 6dac (2.55), 6dag (2.8), 6daj (2.45), 6dal (2.65), 6ma6 (2.18), 6ma7 (2.09), 6ma8 (1.83), 6oo9 (2.25), 6ooa (2.52), 6oob (2.2), 7ks8 (2.5), 7kvp (2.75), 8ewd (2.2), 8ewe (2.3), 8ewl (2.35), 8ewm (2.3), 8ewn (2.1), 8ewp (2.4), 8ewq (2.25), 8ewr (2.2), 8ews (2.15), 8exb (2.05)
Number of TM secondary structures0
Membranome
UniprotCP3A4_HUMAN
Topology in Endoplasmic reticulum membrane
lumenal side
cytoplasmic side
3D view in GLMol | LiteMol | Jmol | iCn3D

Comments: 2j0c and 2j0d have the same calculated positions in the membrane as 1tqn, although conformations of some loops in 2j0c are different.

Verification: Cytochrome P450 3A4, structure 1
Crystallization with detergent (CYMAL-6/CHAPS). This cytochrome has a tentative N-terminal TMH, consistent with the calculated orientation.