1n5m » Acetylcholinesterase
- Type: Monotopic/peripheral (4 classes)
- Class: Alpha/Beta monotopic/peripheral (35 superfamilies)
- Superfamily: Alpha/beta-hydrolases (19 families) CL0028
- Family: Acetylcholinesterase-like (23 proteins) PF00135 IPR002018 PDBsum
- Species: Mus musculus (411 proteins)
- Localization: Eukaryotic plasma membrane (3316 proteins)
| 1n5m >> Acetylcholinesterase | |
|---|---|
| Hydrophobic Thickness or Depth | 3.7 Å |
| Tilt Angle | 28° |
| ΔGtransfer | -6.1 kcal/mol |
| Links to 1n5m | PDB Sum, PDB, MSD, MMDB |
| Topology | extracellular side |
| Resolution | 2.2 |
| Primary PDB represention | 1n5m |
| Other PDB entries representing this structure | 1c2b (4.5), 1c2o (4.2), 1j06 (2.35), 1j07 (2.35), 1ku6 (2.5), 1maa (2.9), 1mah (3.2), 1n5r (2.25), 1q83 (2.65), 1q84 (2.45), 2c0p (2.5), 2c0q (2.5), 2gyu (2.2), 2gyv (2.5), 2gyw (2.4), 2h9y (2.4), 2ha0 (2.2), 2ha2 (2.05), 2ha3 (2.25), 2ha4 (2.56), 2ha5 (2.15), 2ha6 (2.25), 2ha7 (2.66), 2jey (2.7), 2jez (2.6), 2jf0 (2.5), 2jge (2.6), 2jgf (2.5), 2jgg, 2jgh, 2jgi (2.9), 2jgj (2.5), 2jgk (2.9), 2jgl (2.6), 2jgm (2.9), 2whp (2.2), 2whq (2.15), 2whr (2.55), 2wls (2.6), 2wu3 (2.7), 2wu4 (2.4), 2xud (2.65), 2xuf (2.55), 2xug (2.6), 2xuh (2.65), 2xui (2.6), 2xuj (2.65), 2xuk (2.75), 2xuo (2.8), 2xup (2.7), 2xuq (2.7), 3dl4 (2.5), 3dl7 (2.5), 4a16 (2.65), 4b7z (2.3), 4b80 (2.5), 4b81 (2.8), 4b82 (2.1), 4b83 (2.4), 4b84 (2.6), 4b85 (2.1), 4bc0 (3.35), 4bc1 (2.95), 4btl (2.5), 5dtg, 5dti (2.0), 5dtj (2.71) |
| Number of TM secondary structures | 0 |
| Membranome |  |
| Uniprot | ACES_MOUSE |
Comments: Isoform H generates GPI-anchored dimers; disulfide linked. Isoform T generates multiple structures, ranging from monomers and dimers to collagen-tailed and hydrophobic-tailed forms, in which catalytic tetramers are associated with anchoring proteins that attach them to the basal lamina or to cell membranes.