• Type: Monotopic/peripheral (4 classes)
• Class: All alpha monotopic/peripheral (66 superfamilies)
• Superfamily: Heme-dependent peroxidases (1 families) PF03098
• Family: Haem peroxidase (6 proteins) PF03098 IPR019791 PDBsum
• Species: Mus musculus (411 proteins)
• Localization: Endoplasmic reticulum membrane (548 proteins)

1cx2 >> Prostaglandin H2 synthase-2 (cyclooxygenase)
Hydrophobic Thickness or Depth	9.7 Å
Tilt Angle	89°
ΔGtransfer	-37.4 kcal/mol
Links to 1cx2	PDB Sum, PDB, MSD, MMDB
Topology	lumenal side
Resolution	3.0
Primary PDB represention	1cx2
Other PDB entries representing this structure	1cvu (2.4), 1ddx (3.0), 1pxx (2.9), 3hs5 (2.1), 3hs6 (2.4), 3hs7 (2.65), 3krk (2.4), 3ln0 (2.2), 3ln1 (2.4), 3mdl (2.2), 3mqe (2.8), 3nt1 (1.73), 3ntb (2.27), 3ntg (2.19), 3olt (2.45), 3olu (2.35), 3pgh (2.5), 3q7d (2.4), 3qh0 (2.1), 3qmo (3.0), 3rr3 (2.84), 3tzi (2.15), 4cox (2.9), 4e1g (2.1), 4fm5 (2.81), 4m10 (2.01), 4m11 (2.45), 4otj (2.11), 4oty (2.35), 4ph9 (1.81), 4rrw (2.57), 4rrx (2.78), 4rry (2.43), 4rrz (2.57), 4rs0 (2.81), 4rut (2.16), 4z0l (2.29), 5cox (3.0), 5jvy (2.36), 5jvz (2.62), 5jw1 (2.82), 5w58 (2.27), 6bl3 (2.22), 6bl4 (2.22), 6cox (2.8), 6ofy (2.2), 6v3r (2.66)
Number of TM secondary structures	0
Membranome
Uniprot	PGH2_MOUSE

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Download OPM File: 1cx2.pdb

PDB Sum, PDB

Topology in Endoplasmic reticulum membrane

	lumenal side
	cytoplasmic side

3D view in GLMol | LiteMol | Jmol | iCn3D

Comments: May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.