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• Protein Classification

• Types (3 types)
• Classes (11 classes)
• Superfamilies (393 superfamilies)
• Families (668 families)
• Species (539 species)
• Localization (24 types)
• All proteins in OPM (2185 proteins)

• Protein Links

• PDB Sum,
• PDB,
• OCA,
• MPKS,
• PDBTM,
• MPDB,
• CGDB

All proteins in OPM (2185 proteins)

Family	Protein Name	PDB ID	Species	Localization	Num. Subunits	Num. TM Sec. Structs.	Hydrophobic Thickness or Depth (Å)	Tilt Angle (°)	ΔGtransfer (kcal/mol)
1.1.01.01.	Bacteriorhodopsin, trimer, complex with annular lipids	2zzl	Halobacterium salinarum	Archaebac.	3	21	29.8 ± 0.6	0 ± 0	-119.0
1.1.01.01.	Bacteriorhodopsin, different loop conformaton	1fbk	Halobacterium salinarum	Archaebac.	3	21	30.0 ± 1.2	0 ± 0	-127.8
1.1.01.01.	Sensory Rhodopsin	1xio	Anabaena sp.	Bact. Gram-neg inner	1	7	31.9 ± 1.5	13 ± 4	-63.1
1.1.01.01.	Sensory rhodopsin II, monomer	1h68	Natronomonas pharaonis	Archaebac.	1	7	30.3 ± 1.5	15 ± 2	-60.0
1.1.01.01.	Xanthorhodopsin	3ddl	Salinibacter ruber	Bact. Gram-neg inner	1	7	28.2 ± 1.8	11 ± 0	-60.7
1.1.01.01.	Bacteriorhodopsin, monomer	1py6	Halobacterium salinarum	Archaebac.	1	7	29.6 ± 2.2	24 ± 8	-59.7
1.1.01.01.	Bacteriorhodopsin, from cubic phase	1ap9	Halobacterium salinarum	Archaebac.	3	21	30.6 ± 1.2	0 ± 0	-97.8
1.1.01.01.	Archaerhodopsin-2, trimeric	2ei4	Halobacterium sp.	Archaebac.	3	21	30.5 ± 1.2	0 ± 1	-143.9
1.1.01.01.	Proton-pumping rhodopsin-2 from algae	3am6	Acetabularia acetabulum	Eukaryo. plasma	1	7	31.2 ± 1.6	10 ± 1	-65.4
1.1.01.01.	Archaeal-type opsin 2	3ug9	Chlamydomonas reinhardtii	Eukaryo. plasma	2	14	31.0 ± 1.2	0 ± 0	-100.3
1.1.01.01.	Bacteriorhodopsin	1m0l	Halobacterium salinarum	Archaebac.	3	21	31.8 ± 1.1	0 ± 1	-121.1
1.1.01.01.	Archaerhodopsin-2	1vgo	Halobacterium sp.	Archaebac.	1	7	30.7 ± 1.3	18 ± 2	-73.1
1.1.01.01.	Green-light absorbing proteorhodopsin	2l6x	Gamma-proteobacterium	Bact. Gram-neg inner	1	7	27.8 ± 1.3	18 ± 1	-55.2
1.1.01.01.	Sensory rhodopsin II, tetramer	1h2s	Natronomonas pharaonis	Archaebac.	4	18	30.5 ± 1.1	0 ± 0	-123.4
1.1.01.01.	Blue-light absorbing proteorhodopsin	4knf	Gamma-proteobacterium	Bact. Gram-neg inner	5	35	28.4 ± 1.5	1 ± 1	-159.6
1.1.01.01.	Halorhodopsin	1e12	Halobacterium salinarum	Archaebac.	3	21	31.8 ± 1.4	0 ± 1	-126.7
1.1.01.01.	Deltarhodopsin	4fbz	Haloterrigena thermotolerans	Archaebac.	3	21	31.6 ± 0.8	0 ± 0	-110.6
1.1.01.01.	Archaerhodopsin-1	1uaz	Halobacterium sp.	Archaebac.	1	7	31.8 ± 1.3	9 ± 2	-65.3
1.1.01.01.	Halorhodopsin	3a7k	Natronomonas pharaonis	Archaebac.	3	21	33.8 ± 1.4	1 ± 0	-141.3
1.1.01.01.	Proteorhodopsin	4jq6	Gamma-proteobacterium	Archaebac.	5	35	28.4 ± 1.3	0 ± 0	-188.5
1.1.01.02.	Rhodopsin, partially active, photobleached	2i37	Bos taurus	Eukaryo. plasma	1	7	31.9 ± 1.5	5 ± 1	-79.1
1.1.01.02.	C-X-C chemokine receptor type 4, inactive, dimer, complex with antagonist	3odu	Homo sapiens	Eukaryo. plasma	2	17	31.2 ± 1.1	0 ± 0	-129.5
1.1.01.02.	5-hydroxytryptamine receptor 2B	4ib4	Homo sapiens	Eukaryo. plasma	1	7	34.0 ± 2.3	16 ± 2	-69.2
1.1.01.02.	Rhodopsin, inactive, conformation 2	3oax	Bos taurus	Eukaryo. plasma	1	7	30.9 ± 1.4	11 ± 0	-73.6
1.1.01.02.	Rhodopsin, inactive state, a dimer	2i36	Bos taurus	Eukaryo. plasma	2	14	30.0 ± 1.4	4 ± 4	-125.6
1.1.01.02.	Opioid mu receptor	4dkl	Mus musculus	Eukaryo. plasma	2	14	32.0 ± 1.0	5 ± 0	-134.7
1.1.01.02.	Beta-2 adrenergic receptor, inactive state	4gbr	Homo sapiens	Eukaryo. plasma	1	7	31.6 ± 1.3	7 ± 1	-71.7
1.1.01.02.	Sphingosine 1-phosphate receptor 1	3v2y	Homo sapiens	Eukaryo. plasma	1	7	32.2 ± 1.4	10 ± 0	-65.9
1.1.01.02.	Opioid delta receptor	4ej4	Mus musculus	Eukaryo. plasma	1	7	34.4 ± 0.8	11 ± 6	-73.2
1.1.01.02.	5-hydroxytryptamine receptor 1B, conformation 1	4iar	Homo sapiens	Eukaryo. plasma	1	7	33.6 ± 1.8	7 ± 1	-76.4
1.1.01.02.	Beta-2 adrenergic receptor, active state, complex with antibody	3p0g	Homo sapiens	Eukaryo. plasma	1	7	30.1 ± 1.4	9 ± 1	-62.9
1.1.01.02.	Beta-1 adrenergic receptor, inactive, multiple mutations	2vt4	Meleagris gallopavo	Eukaryo. plasma	1	7	32.8 ± 1.6	3 ± 1	-74.6
1.1.01.02.	Muscarinic acetylcholine receptor M3	4daj	Rattus norvegicus	Eukaryo. plasma	1	7	32.2 ± 1.2	5 ± 0	-75.8
1.1.01.02.	Thrombin (proteinase-activated) receptor 1, PAR1	3vw7	Homo sapiens	Eukaryo. plasma	1	7	33.4 ± 1.9	1 ± 0	-72.2
1.1.01.02.	5-hydroxytryptamine receptor 1B, conformation 2	4iaq	Homo sapiens	Eukaryo. plasma	1	7	34.4 ± 1.7	6 ± 1	-77.4
1.1.01.02.	Rhodopsin, active (metarhodopsin II), complex with peptide of transducin	3pqr	Bos taurus	Eukaryo. plasma	1	7	31.8 ± 1.1	9 ± 1	-78.3
1.1.01.02.	Opioid kappa receptor	4djh	Homo sapiens	Eukaryo. plasma	2	14	32.0 ± 0.8	1 ± 0	-146.6
1.1.01.02.	Rhodopsin, inactive, conformation 3	1u19	Bos taurus	Eukaryo. plasma	1	7	31.2 ± 1.5	12 ± 1	-71.9
1.1.01.02.	Rhodopsin, active (metarhodopsin II), without transducin peptide, dimer	3pxo	Bos taurus	Eukaryo. plasma	2	14	31.8 ± 1.2	0 ± 0	-125.4
1.1.01.02.	Adenosine receptor A2a, partially active state, engineered, complex with agonist	2ydv	Homo sapiens	Eukaryo. plasma	1	7	31.0 ± 1.3	10 ± 0	-61.4
1.1.01.02.	Muscarinic acetylcholine receptor M2	3uon	Homo sapiens	Eukaryo. plasma	1	7	31.8 ± 2.1	4 ± 2	-68.5
1.1.01.02.	Adenosine receptor A2a, complex with antagonist	3uza	Homo sapiens	Eukaryo. plasma	1	7	31.6 ± 0.6	8 ± 1	-72.5
1.1.01.02.	Squid rhodopsin, inactive, complex with inverse agonist 11-cis retinal	2ziy	Todarodes pacificus	Eukaryo. plasma	1	7	32.9 ± 1.7	11 ± 2	-75.1
1.1.01.02.	Adenosine receptor A2a, partially active state, complex with agonist	3qak	Homo sapiens	Eukaryo. plasma	1	7	29.8 ± 1.2	9 ± 0	-70.0
1.1.01.02.	Rhodopsin, constitutively active mutant (metarhodopsin II), dimer	2x72	Bos taurus	Eukaryo. plasma	2	14	30.0 ± 0.6	0 ± 0	-132.0
1.1.01.02.	Adenosine receptor A2a, inactive state, engineered, complex with inverse agonist	3pwh	Homo sapiens	Eukaryo. plasma	1	7	31.0 ± 1.3	9 ± 0	-67.3
1.1.01.02.	Adenosine receptor A2a, inactive state, complex with antagonist	3eml	Homo sapiens	Eukaryo. plasma	1	7	31.8 ± 1.2	8 ± 12	-66.1
1.1.01.02.	TM1-TM2 fragment of fungal STE2 receptor	2k9p	Saccharomyces cerevisiae	Eukaryo. plasma	1	2	29.8 ± 3.1	21 ± 4	-10.5
1.1.01.02.	Adenosine receptor A2a, complex with antibody	3vga	Homo sapiens	Eukaryo. plasma	1	7	30.4 ± 1.4	7 ± 2	-62.8
1.1.01.02.	Dopamine D3 receptor	3pbl	Homo sapiens	Eukaryo. plasma	1	7	33.0 ± 1.8	8 ± 1	-56.6
1.1.01.02.	Rhodopsin, inactive, complex with inverse agonist, 11-cis retinal	1gzm	Bos taurus	Eukaryo. plasma	1	7	32.2 ± 1.5	11 ± 1	-75.6
1.1.01.02.	Squid rhodopsin, inactive, complex with inverse agonist 11-cis retinal, dimer	2z73	Todarodes pacificus	Eukaryo. plasma	2	14	32.9 ± 1.0	0 ± 1	-143.3
1.1.01.02.	Beta-1 adrenergic receptor, inactive, complex with antagonist	2ycw	Meleagris gallopavo	Eukaryo. plasma	1	7	32.2 ± 1.3	2 ± 0	-77.8
1.1.01.02.	Beta-2 adrenergic receptor, active state, complex with G-protein	3sn6	Homo sapiens	Eukaryo. plasma	1	7	31.0 ± 1.6	8 ± 1	-68.2
1.1.01.02.	Melanocortin-4 receptor model (active state) with agonist NDP-MSH	2iqr	Homo sapiens	Eukaryo. plasma	1	7	33.5 ± 2.0	24 ± 0	-60.6
1.1.01.02.	Beta-2 adrenergic receptor, inactive state, dimer	2rh1	Homo sapiens	Eukaryo. plasma	2	14	31.8 ± 0.9	0 ± 1	-143.2
1.1.01.02.	Nociceptin receptor	4ea3	Homo sapiens	Eukaryo. plasma	1	7	32.0 ± 1.2	7 ± 1	-65.6
1.1.01.02.	C-X-C chemokine receptor type 4, inactive, complex with antagonist	3oe6	Homo sapiens	Eukaryo. plasma	1	7	35.3 ± 2.5	8 ± 7	-79.7
1.1.01.02.	Neurotensin receptor type 1	4grv	Rattus norvegicus	Eukaryo. plasma	1	7	31.6 ± 1.1	4 ± 1	-75.1
1.1.01.02.	Histamine H1 receptor	3rze	Homo sapiens	Eukaryo. plasma	1	7	32.0 ± 1.4	1 ± 1	-72.4
1.1.01.02.	Melanocortin-4 receptor model (inactive state) with antagonist AGRP	2iqv	Homo sapiens	Eukaryo. plasma	1	7	31.9 ± 1.1	19 ± 0	-49.1
1.1.01.02.	C-X-C chemokine receptor type 4, inactive, with cyclic peptide antagonist	3oe0	Homo sapiens	Eukaryo. plasma	2	14	32.2 ± 2.0	5 ± 6	-133.2
1.1.01.02.	Adenosine receptor A2a, inactive state, with annular lipids	4eiy	Homo sapiens	Eukaryo. plasma	1	7	32.2 ± 1.2	18 ± 0	-70.4
1.1.01.02.	Opsin, active, retinal-free state, dimer	3cap	Bos taurus	Eukaryo. plasma	2	14	30.8 ± 1.1	0 ± 0	-130.1
1.1.01.02.	C-X-C chemokine receptor type 1	2lnl	Homo sapiens	Eukaryo. plasma	1	7	30.2 ± 0.9	19 ± 6	-54.4
1.1.01.02.	Beta-1 adrenergic receptor, inactive, dimer	4gpo	Meleagris gallopavo	Eukaryo. plasma	2	14	30.8 ± 1.2	0 ± 0	-144.8
1.1.01.02.	Beta-1 adrenergic receptor, inactive, complex with agonist	2y02	Meleagris gallopavo	Eukaryo. plasma	1	7	31.4 ± 1.3	2 ± 0	-76.9
1.1.01.03.	Ectodomain of G-protein coupled receptor Mth	1fjr	Drosophila melanogaster	Eukaryo. plasma	1	0	1.8 ± 1.5	56 ± 13	-4.3
1.1.01.04.	Smoothened homolog	4jkv	Homo sapiens	Eukaryo. plasma	2	14	31.9 ± 1.2	0 ± 0	-98.5
1.1.02.01.	Photosynthetic reaction center, more complete structure	2j8d	Rhodobacter sphaeroides	Bact. Gram-neg inner	3	11	31.6 ± 1.0	5 ± 0	-135.5
1.1.02.01.	Photosynthetic reaction center, complex with cytochrome c	1eys	Thermochromatium tepidum	Bact. Gram-neg inner	3	11	31.6 ± 1.0	2 ± 0	-116.0
1.1.02.01.	Photosynthetic reaction center	2j8c	Rhodobacter sphaeroides	Bact. Gram-neg inner	3	11	31.8 ± 0.8	2 ± 0	-129.6
1.1.02.01.	Photosynthetic reaction center, complex with cytochrome c	1l9b	Rhodobacter sphaeroides	Bact. Gram-neg inner	3	11	31.6 ± 0.8	3 ± 0	-127.3
1.1.02.01.	Photosynthetic reaction center, complex with cytochrome c	1dxr	Rhodopseudomonas viridis	Bact. Gram-neg inner	3	11	31.8 ± 0.7	5 ± 0	-121.8
1.1.02.02.	Photosystem I	3lw5	Pisum sativum	Thylakoid	11	46	29.8 ± 0.1	2 ± 0	-311.1
1.1.02.02.	Photosystem I	1jb0	Thermosynechococcus elongatus	Thylakoid	9	32	31.4 ± 0.4	1 ± 0	-285.7
1.1.02.02.	Photosystem I, trimeric complex	3pcq	Thermosynechococcus elongatus	Thylakoid	27	96	29.8 ± 0.8	0 ± 0	-429.6
1.1.02.03.	Photosystem II	3a0b	Thermosynechococcus vulcanus	Thylakoid	34	72	31.8 ± 0.4	0 ± 0	-397.1
1.1.02.03.	Photosystem II, monomeric form	3kzi	Thermosynechococcus elongatus	Thylakoid	16	36	31.8 ± 0.5	0 ± 0	-310.1
1.1.02.03.	Photosystem II	3bz1	Thermosynechococcus elongatus	Thylakoid	34	72	31.6 ± 0.4	0 ± 0	-409.7
1.1.02.03.	Photosystem II	3arc	Thermosynechococcus vulcanus	Thylakoid	32	70	31.8 ± 0.0	0 ± 0	-406.5
1.1.03.01.	Light-harvesting protein B-870, beta chain	1wrg	Rhodospirillum rubrum	Bact. Gram-neg inner	1	1	27.0 ± 4.7	44 ± 1	-23.9
1.1.03.01.	Light-harvesting protein B-875, beta chain	1jo5	Rhodobacter sphaeroides	Bact. Gram-neg inner	1	1	29.6 ± 1.5	20 ± 2	-24.7
1.1.03.01.	Light-harvesting complex LH2	1nkz	Rhodopseudomonas acidophila	Bact. Gram-neg inner	18	18	31.8 ± 0.6	0 ± 0	-193.5
1.1.03.01.	Light-harvesting complex LH3	1ijd	Rhodopseudomonas acidophila	Bact. Gram-neg inner	18	18	29.8 ± 0.7	0 ± 0	-174.6
1.1.03.01.	Light-harvesting complex	1lgh	Rhodospirillum molischianum	Bact. Gram-neg inner	16	16	29.7 ± 0.5	0 ± 0	-163.4
1.1.03.01.	Light-harvesting complex LH1, alpha chain	1xrd	Rhodospirillum rubrum	Bact. Gram-neg inner	1	1	30.3 ± 3.1	30 ± 4	-30.5
1.1.03.02.	Light-Harvesting Complex II	2bhw	Pisum sativum	Thylakoid	3	9	29.4 ± 1.0	0 ± 0	-123.2
1.1.03.02.	Light-harvesting complex CP29	3pl9	Spinacia oleracea	Thylakoid	1	3	29.8 ± 1.6	2 ± 2	-66.6
1.1.03.02.	Light-Harvesting Complex II	1rwt	Spinacia oleracea	Thylakoid	3	9	30.0 ± 0.7	0 ± 0	-154.0
1.1.04.01.	Respiratory complex I	3rko	Escherichia coli	Bact. Gram-neg inner	6	58	29.6 ± 0.0	9 ± 0	-236.7
1.1.04.01.	Respiratory complex I	4hea	Thermus thermophilus	Bact. Gram-neg inner	7	67	29.8 ± 0.5	10 ± 0	-299.7
1.1.05.01.	Polysulfide reductase, substrate-bound state	2vpx	Thermus thermophilus	Bact. Gram-neg inner	2	16	27.1 ± 1.1	0 ± 1	-103.3
1.1.05.01.	Polysulfide reductase, inactive state	2vpz	Thermus thermophilus	Bact. Gram-neg inner	2	16	29.8 ± 1.5	1 ± 0	-105.2
1.1.05.02.	Formate dehydrogenase	1kqf	Escherichia coli	Bact. Gram-neg inner	6	15	33.7 ± 1.1	0 ± 0	-141.9
1.1.05.03.	Respiratory Nitrate Reductase	1q16	Escherichia coli	Bact. Gram-neg inner	2	10	30.1 ± 0.9	0 ± 0	-126.9
1.1.05.04.	Succinate dehydrogenase (mitochondrial respiratory complex II)	1zoy	Sus scrofa	Mitochon. inner	2	6	29.8 ± 1.1	3 ± 6	-52.6
1.1.05.04.	Fumarate reductase	2bs2	Wolinella succinogenes	Bact. Gram-neg inner	2	10	31.4 ± 1.3	2 ± 0	-118.8
1.1.05.04.	Succinate dehydrogenase (mitochondrial respiratory complex II)	1yq3	Gallus gallus	Mitochon. inner	2	6	29.6 ± 1.8	4 ± 6	-56.7
1.1.05.04.	Succinate dehydrogenase (mitochondrial respiratory complex II)	3vr8	Ascaris suum	Mitochon. inner	2	6	30.4 ± 1.2	10 ± 1	-57.1
1.1.05.05.	Fumarate reductase	1kf6	Escherichia coli	Bact. Gram-neg inner	2	6	30.2 ± 1.2	14 ± 2	-65.6
1.1.05.05.	Succinate dehydrogenase	1nek	Escherichia coli	Bact. Gram-neg inner	6	18	32.0 ± 0.6	0 ± 0	-183.5
1.1.05.06.	Ni/Fe-hydrogenase complex	4gd3	Escherichia coli	Bact. Gram-neg inner	3	6	27.2 ± 1.4	9 ± 1	-42.4
1.1.06.01.	Cytochrome b6f	1q90	Chlamydomonas reinhardtii	Thylakoid	16	26	31.8 ± 1.0	0 ± 1	-226.4
1.1.06.01.	Cytochrome bc1, mitochondrial	3cx5	Saccharomyces cerevisiae	Mitochon. inner	10	24	27.2 ± 0.6	0 ± 0	-173.9
1.1.06.01.	Cytochrome b6f, slightly different structure 1	2d2c	Mastigocladus laminosus	Thylakoid	16	26	28.6 ± 0.6	0 ± 0	-156.9
1.1.06.01.	Cytochrome bc1, bacterial	2qjy	Rhodobacter sphaeroides	Bact. Gram-neg inner	6	20	30.2 ± 0.6	0 ± 0	-188.6
1.1.06.01.	Cytochrome bc1, bacterial	2yiu	Paracoccus denitrificans	Bact. Gram-neg inner	6	20	29.8 ± 0.5	0 ± 0	-188.8
1.1.06.01.	Cytochrome b6f	2e74	Mastigocladus laminosus	Thylakoid	16	26	31.2 ± 0.8	0 ± 0	-222.1
1.1.06.01.	Cytochrome b6f, slightly different structure 2	4h13	Mastigocladus laminosus	Thylakoid	16	26	31.6 ± 0.6	0 ± 0	219.6
1.1.06.01.	Cytochrome b6f	2zt9	Nostoc sp.	Thylakoid	16	26	31.2 ± 1.0	0 ± 1	-214.2
1.1.06.01.	Cytochrome bc1, mitochondrial, different structure of complex 2	1pp9	Bos taurus	Mitochon. inner	10	26	29.8 ± 0.3	6 ± 0	-179.3
1.1.06.01.	Cytochrome bc1, mitochondrial, different structure of complex 1	2fyu	Bos taurus	Mitochon. inner	12	26	29.8 ± 0.5	0 ± 0	-182.9
1.1.06.01.	Cytochrome bc1, bacterial	1zrt	Rhodobacter capsulatus	Bact. Gram-neg inner	6	20	29.9 ± 0.9	0 ± 0	-178.6
1.1.06.01.	Cytochrome bc1, mitochondrial	3h1j	Gallus gallus	Mitochon. inner	10	24	28.2 ± 0.6	0 ± 0	-184.8
1.1.06.01.	Cytochrome bc1, mitochondrial, different structure of complex 3	2a06	Bos taurus	Mitochon. inner	9	23	29.8 ± 0.3	2 ± 0	-166.2
1.1.06.01.	Cytochrome bc1, mitochondrial	1l0l	Bos taurus	Mitochon. inner	12	26	30.0 ± 0.6	0 ± 0	-186.6
1.1.07.01.	Bacterial cytochrome c oxidase	1m56	Rhodobacter sphaeroides	Bact. Gram-neg inner	4	22	29.6 ± 1.8	3 ± 0	-173.7
1.1.07.01.	Bacterial cytochrome c oxidase, cbb3 type	3mk7	Pseudomonas stutzeri	Bact. Gram-neg inner	4	17	32.8 ± 1.2	4 ± 4	-119.2
1.1.07.01.	Nitric oxide reductase	3o0r	Pseudomonas aeruginosa	Bact. Gram-neg inner	2	13	31.7 ± 1.6	5 ± 0	-107.7
1.1.07.01.	Bacterial cytochrome c oxidase	1qle	Paracoccus denitrificans	Bact. Gram-neg inner	4	22	31.7 ± 1.3	4 ± 0	-167.4
1.1.07.01.	Ubiquinol Oxidase	1fft	Escherichia coli	Bact. Gram-neg inner	3	19	29.5 ± 0.6	12 ± 0	-82.3
1.1.07.01.	Bacterial cytochrome c oxidase, caa3-type	2yev	Thermus thermophilus	Bact. Gram-neg inner	3	21	31.2 ± 0.8	6 ± 0	-146.1
1.1.07.01.	EM model of mitochondrial supercomplex	2ybb	Bos taurus	Mitochon. inner	26	115	30.0 ± 0.3	9 ± 0	-310.3
1.1.07.01.	Mitochondrial cytochrome c oxidase	1v55	Bos taurus	Mitochon. inner	20	56	27.8 ± 0.9	0 ± 0	-209.1
1.1.07.01.	Bacterial cytochrome c oxidase	3s8g	Thermus thermophilus	Bact. Gram-neg inner	3	15	31.2 ± 1.1	7 ± 0	-112.3
1.1.07.01.	Nitric oxide reductase	3ayf	Bacillus stearothermophilus	Bact. Gram-pos plas.	1	14	31.6 ± 0.8	8 ± 0	-109.3
1.1.08.01.	F1F0 ATP synthase, F0 complex	4f4s	Saccharomyces cerevisiae	Mitochon. inner	10	20	38.4 ± 1.3	0 ± 0	-89.9
1.1.08.01.	ATP synthase of chloroplast	3v3c	Pisum sativum	Thylakoid	14	28	32.0 ± 1.0	0 ± 0	-111.5
1.1.08.01.	F1F0 ATP synthase, F0 complex, conformation 1	2x2v	Bacillus pseudofirmus	Bact. Gram-pos plas.	13	26	35.3 ± 1.2	0 ± 0	-137.7
1.1.08.01.	F1F0 ATP synthase, F0 complex	2xqu	Arthrospira platensis	Thylakoid	15	30	31.8 ± 0.8	0 ± 0	-129.7
1.1.08.01.	F1F0 ATP synthase subunit c	1wu0	Bacillus ps3	Bact. Gram-pos plas.	1	2	31.9 ± 2.7	44 ± 1	-23.2
1.1.08.01.	F1F0 ATP synthase subunit c	1a91	Escherichia coli	Bact. Gram-neg inner	1	2	36.1 ± 6.7	21 ± 3	-21.4
1.1.08.01.	F1F0 ATP synthase, F0F1 complex, more complete model	4b2q	Saccharomyces cerevisiae	Mitochon. inner	10	20	38.4 ± 0.9	0 ± 0	-115.7
1.1.08.01.	F1F0 ATP synthase, F0 complex	1c17	Escherichia coli	Bact. Gram-neg inner	13	28	34.6 ± 1.2	4 ± 0	-149.9
1.1.08.01.	F1F0 ATP synthase, F0F1 complex	2xok	Saccharomyces cerevisiae	Mitochon. inner	10	20	35.3 ± 1.3	0 ± 0	-58.9
1.1.08.01.	F-type Sodium ATPase	1yce	Ilyobacter tartaricus	Bact. Gram-neg inner	11	22	37.0 ± 0.5	0 ± 0	-104.0
1.1.08.01.	ATP synthase subunit b	1b9u	Escherichia coli	Bact. Gram-neg inner	1	1	29.8 ± 4.0	41 ± 2	-23.1
1.1.08.01.	V-type Sodium ATPase	2bl2	Enterococcus hirae	Bact. Gram-neg inner	10	40	35.6 ± 0.7	0 ± 0	-189.6
1.1.08.01.	F1F0 ATP synthase, F0 complex, conformation 2	3zo6	Bacillus pseudofirmus	Bact. Gram-pos plas.	12	24	39.6 ± 1.1	1 ± 0	-130.6
1.1.08.01.	ATP synthase of chloroplast	2w5j	Spinacia oleracea	Thylakoid	14	28	32.8 ± 0.7	0 ± 0	-116.3
1.1.08.01.	F1F0 ATP synthase, F0F1 complex, different conformation	3zry	Saccharomyces cerevisiae	Mitochon. inner	10	20	33.6 ± 1.9	4 ± 0	-56.0
1.1.08.01.	F1F0 ATP synthase, F0 complex	3zk1	Fusobacterium nucleatum	Bact. Gram-neg inner	11	22	36.6 ± 2.3	0 ± 0	-84.3
1.1.09.01.	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3tlm	Bos taurus	Endoplasm. reticulum	1	10	26.8 ± 0.0	22 ± 0	-57.4
1.1.09.01.	Sodium-potassium pump, E2-Pi state	3b8e	Sus scrofa	Eukaryo. plasma	3	12	30.7 ± 0.9	12 ± 0	-93.6
1.1.09.01.	Calcium ATPase, E2 state (Ca-free), conformation 8	2zbg	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.0 ± 1.7	21 ± 0	-66.5
1.1.09.01.	Sodium-potassium pump, gastric, different conformation	2yn9	Sus scrofa	Eukaryo. plasma	2	11	30.6 ± 0.8	10 ± 0	-85.9
1.1.09.01.	Copper efflux ATPase	3rfu	Legionella pneumophila	Bact. Gram-neg inner	1	8	30.0 ± 0.4	16 ± 1	-72.1
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 3	3b9b	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.9 ± 1.6	16 ± 2	-58.1
1.1.09.01.	Plasma membrane ATPase 2, E1-ATP state	3b8c	Arabidopsis thaliana	Eukaryo. plasma	1	10	29.5 ± 1.5	9 ± 0	-56.8
1.1.09.01.	Calcium ATPase, E1 Mg2+ state, complex with sarcolipin	3w5a	Oryctolagus cuniculus	Endoplasm. reticulum	2	11	26.8 ± 0.7	30 ± 0	-67.4
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 4	3b9r	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	26.8 ± 0.0	25 ± 0	-44.1
1.1.09.01.	Calcium ATPase, E1 Ca2+ state, complex with sarcolipin	4h1w	Oryctolagus cuniculus	Endoplasm. reticulum	2	11	27.6 ± 1.0	27 ± 1	-67.6
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 5	3fpb	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	27.0 ± 2.3	23 ± 0	-64.9
1.1.09.01.	Plasma membrane ATPase	1mhs	Neurospora crassa	Eukaryo. plasma	2	20	29.5 ± 0.2	7 ± 0	-109.6
1.1.09.01.	Calcium ATPase, E1-2Ca state, conformation 1	3ar2	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.6 ± 0.9	25 ± 0	-70.9
1.1.09.01.	Calcium ATPase, E2 state (Ca-free), conformation 1	2agv	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.7 ± 2.2	20 ± 2	-61.5
1.1.09.01.	Calcium ATPase, E2 state (Ca-free), conformation 2	2by4	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.8 ± 1.3	24 ± 1	-63.7
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 6	1xp5	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	27.4 ± 1.1	25 ± 0	-58.5
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 1	1wpg	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.6 ± 1.1	20 ± 0	-70.4
1.1.09.01.	Calcium ATPase, E2 state, Ca-free, conformation 3	2ear	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.0 ± 1.2	19 ± 1	-58.4
1.1.09.01.	Sodium-potassium pump, E2-Pi state	2zxe	Squalus acanthias	Eukaryo. plasma	3	12	31.9 ± 1.8	9 ± 0	-96.3
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 7	3n5k	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	28.4 ± 1.3	22 ± 2	-64.8
1.1.09.01.	Calcium ATPase, E1-ATP state	1t5s	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.7 ± 1.6	22 ± 1	-58.6
1.1.09.01.	Calcium ATPase, E2 state, Ca-free, conformation 7	3ar9	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.0 ± 0.9	20 ± 0	-73.8
1.1.09.01.	Calcium ATPase, E2 state (Ca-free), conformation 4	3fps	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.0 ± 0.9	16 ± 0	-53.5
1.1.09.01.	Calcium ATPase, E1-2Ca state, conformation 2	3ba6	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.8 ± 0.7	19 ± 0	-59.4
1.1.09.01.	Sodium-potassium pump, gastric	2xzb	Sus scrofa	Eukaryo. plasma	2	11	29.7 ± 1.2	9 ± 0	-91.4
1.1.09.01.	Calcium ATPase, E1P-ADP state	2zbd	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	31.8 ± 1.4	22 ± 2	-70.6
1.1.09.01.	Calcium ATPase, E2 state (Ca-free), conformation 5	1kju	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	33.8 ± 0.2	26 ± 1	-68.6
1.1.09.01.	Calcium ATPase, E1-2Ca state, conformation 3	1su4	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.0 ± 2.7	26 ± 1	-68.6
1.1.09.01.	Sodium-potassium pump, E2-Pi state, slightly different conf.	3kdp	Sus scrofa	Eukaryo. plasma	3	12	31.4 ± 1.4	7 ± 0	-95.3
1.1.09.01.	Copper efflux ATPase, CopA	3j08	Archaeoglobus fulgidus	Archaebac.	2	16	27.6 ± 0.8	0 ± 0	-72.3
1.1.09.01.	Sodium-potassium pump, different conformation	3n23	Sus scrofa	Eukaryo. plasma	3	12	29.9 ± 0.9	6 ± 0	-96.0
1.1.09.01.	Calcium ATPase, E2 state (Ca-free), conformation 6	2zbe	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	28.0 ± 0.7	16 ± 0	-55.4
1.1.09.01.	Calcium ATPase, E1-2Ca state, conformation 4	2c9m	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.8 ± 1.2	27 ± 1	-54.3
1.1.09.01.	Copper efflux ATPase, CopA, alternative conformation	3j09	Archaeoglobus fulgidus	Archaebac.	2	16	27.0 ± 0.1	1 ± 0	-23.5
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 2	3ar8	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	28.6 ± 1.8	19 ± 0	-60.6
1.1.10.01.	ABC transporter BtuCD, symmetric structure	1l7v	Escherichia coli	Bact. Gram-neg inner	2	22	30.7 ± 1.1	0 ± 1	-121.0
1.1.10.01.	ABC transporter BtuCD, nucleotide-bound state	4fi3	Escherichia coli	Bact. Gram-neg inner	2	20	29.0 ± 1.0	0 ± 0	-118.3
1.1.10.01.	ABC transporter BtuCD, complex with BtuF, structure 2	4dbl	Escherichia coli	Bact. Gram-neg inner	2	20	29.4 ± 1.0	4 ± 0	-123.4
1.1.10.01.	Hemin transport system permease, HmuU	4g1u	Yersinia pestis	Bact. Gram-neg inner	2	20	29.8 ± 0.5	0 ± 0	-114.3
1.1.10.01.	ABC transporter BtuCD, complex with BtuF, structure 1	2qi9	Escherichia coli	Bact. Gram-neg inner	2	22	29.4 ± 0.9	4 ± 4	-123.5
1.1.10.01.	ABC transporter permease HI1471	2nq2	Haemophilus influenzae	Bact. Gram-neg inner	2	20	31.9 ± 0.9	1 ± 1	-124.2
1.1.10.02.	Molybdate transporter ModBC, open state	3d31	Methanosarcina acetivorans	Archaebac.	2	12	29.8 ± 1.5	1 ± 0	-91.6
1.1.10.02.	Maltose transporter MalFGK, outward conformation	3puw	Escherichia coli	Bact. Gram-neg inner	2	14	29.8 ± 1.3	3 ± 1	-94.0
1.1.10.02.	Maltose transporter MalFGK, complex with protein EIIAglc	4jbw	Escherichia coli	Bact. Gram-neg inner	2	14	29.8 ± 0.8	4 ± 1	-107.8
1.1.10.02.	Maltose transporter MalFGK, a pre-translocation state	3puz	Escherichia coli	Bact. Gram-neg inner	2	14	29.0 ± 0.8	7 ± 0	-107.2
1.1.10.02.	Methionine importer MetNI, conformation 2	3tuj	Escherichia coli	Bact. Gram-neg inner	2	10	30.4 ± 1.3	7 ± 1	-84.5
1.1.10.02.	Maltose transporter MalFGK, inward conformation, TMH 1 deleted	3fh6	Escherichia coli	Bact. Gram-neg inner	2	13	29.9 ± 0.6	3 ± 1	-97.8
1.1.10.02.	Methionine importer MetNI, conformation 3	3dhw	Escherichia coli	Bact. Gram-neg inner	2	10	29.2 ± 1.0	1 ± 0	-82.5
1.1.10.02.	Methionine importer MetNI, conformation 1	3tui	Escherichia coli	Bact. Gram-neg inner	2	10	30.2 ± 1.3	1 ± 1	-81.0
1.1.10.02.	Molybdate transporter ModBC, open state	2onk	Archaeoglobus fulgidus	Archaebac.	2	12	32.0 ± 1.7	0 ± 1	-100.7
1.1.10.03.	ABC transporter, inward-facing conformation	3qf4	Thermotoga maritima	Bact. Gram-neg inner	2	12	32.0 ± 0.8	2 ± 0	-104.9
1.1.10.03.	Lipid flippase MsbA, open state	3b60	Salmonella enterica	Bact. Gram-neg inner	2	12	31.8 ± 0.9	0 ± 0	-98.5
1.1.10.03.	Multidrug ABC transporter SAV1866, closed state	2hyd	Staphylococcus aureus	Bact. Gram-pos plas.	2	12	31.8 ± 1.7	3 ± 3	-110.5
1.1.10.03.	Lipid flippase MsbA, closed state	3b5x	Vibrio cholerae	Bact. Gram-neg inner	2	12	30.2 ± 1.0	0 ± 0	-58.7
1.1.10.04.	Multidrug resistance protein pgp-1	4f4c	Caenorhabditis elegans	Eukaryo. plasma	1	14	32.0 ± 1.8	6 ± 0	-105.1
1.1.10.04.	P-glycoprotein, inward-facing conformation	3g5u	Mus musculus	Eukaryo. plasma	1	12	31.8 ± 1.2	4 ± 0	-100.6
1.1.10.05.	Mitochondrial ABC transporter ABCB10, conformation 1	4ayt	Homo sapiens	Mitochon. inner	2	12	30.4 ± 0.8	0 ± 0	-79.7
1.1.10.05.	Mitochondrial ABC transporter ABCB10, conformation 2	4ayw	Homo sapiens	Mitochon. inner	2	12	29.0 ± 0.8	0 ± 0	-65.8
1.1.10.05.	Mitochondrial ABC transporter ABCB10, conformation 3	4ayx	Homo sapiens	Mitochon. inner	2	12	30.0 ± 0.6	0 ± 0	-76.8
1.1.10.05.	Mitochondrial ABC transporter ABCB10, conformation 4	3zdq	Homo sapiens	Mitochon. inner	2	12	30.8 ± 0.5	1 ± 0	-71.8
1.1.11.01.	Protein translocase SecY, mutant with full-plug (TM2a) deletion	2yxr	Methanococcus jannaschii	Archaebac.	3	12	29.7 ± 0.8	4 ± 4	-95.6
1.1.11.01.	Protein translocase SecY, pre-open state	2zjs	Thermus thermophilus	Bact. Gram-neg inner	2	11	30.7 ± 1.2	7 ± 0	-100.7
1.1.11.01.	Protein translocase SecY, closed state, mutant	1rh5	Methanococcus jannaschii	Archaebac.	3	12	29.0 ± 1.1	10 ± 0	-93.4
1.1.11.01.	Protein translocase SecY, mutant with half-plug (TM2a) deletion	2yxq	Methanococcus jannaschii	Archaebac.	3	12	29.2 ± 1.1	6 ± 0	-89.1
1.1.11.01.	Protein translocase SecY, closed state	1rhz	Methanococcus jannaschii	Archaebac.	3	12	29.4 ± 1.0	5 ± 0	-89.2
1.1.11.01.	Protein translocase SecY, closed state	2zqp	Thermus thermophilus	Bact. Gram-neg inner	2	11	29.8 ± 0.4	9 ± 0	-99.4
1.1.11.01.	Protein translocase SecY, partialy open	3mp7	Pyrococcus furiosus	Archaebac.	2	10	30.1 ± 1.0	5 ± 6	-94.0
1.1.11.01.	Protein translocase Sec61, complex with ribosome	2wwb	Canis lupus familiaris	Endoplasm. reticulum	3	12	26.3 ± 0.5	13 ± 0	-60.5
1.1.11.01.	Protein translocase SecY, complex with ribosome 1	3dkn	Methanococcus jannaschii	Archaebac.	3	12	27.8 ± 1.8	2 ± 0	-80.9
1.1.11.01.	Ribosome-SecYE complex	3j01	Escherichia coli	Bact. Gram-neg inner	2	13	28.6 ± 0.0	5 ± 0	-86.4
1.1.11.01.	Protein translocase SecY, complex with SecA	3din	Thermotoga maritima	Bact. Gram-neg inner	3	13	26.9 ± 0.1	5 ± 0	-63.3
1.1.11.01.	Protein translocase SecY, complex with ribosome 2	3bo0	Methanococcus jannaschii	Archaebac.	3	12	29.6 ± 1.2	6 ± 2	-78.0
1.1.12.01.	Potassium channel subfamily K member 1	3ukm	Homo sapiens	Eukaryo. plasma	2	12	31.8 ± 1.0	0 ± 0	-108.7
1.1.12.01.	Potassium channel KcsA, open inactivated state	3f5w	Streptomyces lividans	Bact. Gram-pos plas.	4	8	29.2 ± 0.7	0 ± 0	-83.5
1.1.12.01.	Multi-ligand gated K(+) channel, TrkA, mutant	4gx0	Geobacter sulfurreducens	Bact. Gram-neg inner	4	8	31.8 ± 1.3	0 ± 0	-109.5
1.1.12.01.	Potassium channel KcsA, complex with Rb+	3fb7	Streptomyces lividans	Bact. Gram-pos plas.	4	8	28.6 ± 1.2	0 ± 0	-79.0
1.1.12.01.	Potassium channel Kv1.2., full-length	3lut	Rattus norvegicus	Eukaryo. plasma	4	24	25.1 ± 0.5	0 ± 0	-153.1
1.1.12.01.	Potassium channel KvAP, sensor domain, NMR model	2kyh	Aeropyrum pernix	Archaebac.	1	5	28.6 ± 1.4	19 ± 4	-44.6
1.1.12.01.	Potassium channel Kv1.2.	2a79	Rattus norvegicus	Eukaryo. plasma	4	28	29.8 ± 1.5	0 ± 0	-147.0
1.1.12.01.	Potassium channel KscA, complex with charibdotoxin	2a9h	Streptomyces lividans	Bact. Gram-pos plas.	4	8	31.8 ± 1.4	0 ± 1	-105.1
1.1.12.01.	Multi-ligand gated K(+) channel, TrkA	4gx5	Geobacter sulfurreducens	Bact. Gram-neg inner	4	8	31.6 ± 0.7	0 ± 0	-94.6
1.1.12.01.	Potassium channel KvAP, sensor domain	1ors	Aeropyrum pernix	Archaebac.	1	5	31.5 ± 2.2	19 ± 1	-50.3
1.1.12.01.	Calcium-gated potassium channel MthK	3ldc	Methanobacterium thermoautotrophicum	Archaebac.	4	8	29.8 ± 0.8	0 ± 0	-72.4
1.1.12.01.	Potassium channel KcsA, 17A opening conformer	3f7y	Streptomyces lividans	Bact. Gram-pos plas.	4	8	31.3 ± 1.3	0 ± 0	-82.3
1.1.12.01.	Voltage-gated K+ channel	4h33	Listeria monocytogenes	Bact. Gram-pos plas.	4	8	33.2 ± 1.9	0 ± 0	-115.9
1.1.12.01.	Bacterial cyclic nucleotide regulated ion channel, different conformation	2zd9	Rhizobium loti	Bact. Gram-neg inner	4	24	31.6 ± 1.2	0 ± 0	-192.8
1.1.12.01.	Potassium channel KvAP	1orq	Aeropyrum pernix	Archaebac.	4	12	29.3 ± 1.6	0 ± 0	-78.6
1.1.12.01.	NaK potassium channel, closed state	2ahy	Bacillus cereus	Bact. Gram-pos plas.	4	12	29.5 ± 0.7	0 ± 1	-105.7
1.1.12.01.	NaK-NavSulP chimera channel	3vou	Sulfitobacter sp.	Bact. Gram-neg inner	4	8	30.4 ± 0.8	0 ± 0	-100.1
1.1.12.01.	NaK potassium channel, open state	3e86	Bacillus cereus	Bact. Gram-pos plas.	4	12	27.6 ± 0.9	0 ± 0	-90.0
1.1.12.01.	Potassium channel KcsA, 23A opening conformer	3f7v	Streptomyces lividans	Bact. Gram-pos plas.	4	8	30.1 ± 1.1	0 ± 0	-95.2
1.1.12.01.	Voltage-gated sodium channel NavAb, different conformation	4ekw	Arcobacter butzleri	Bact. Gram-neg inner	4	24	29.4 ± 0.5	0 ± 0	-201.0
1.1.12.01.	Bacterial cyclic nucleotide regulated ion channel	3beh	Rhizobium loti	Bact. Gram-neg inner	4	28	30.6 ± 0.8	0 ± 0	-205.7
1.1.12.01.	Potassium channel subfamily K member 4, different conformation	4i9w	Homo sapiens	Eukaryo. plasma	2	8	30.8 ± 1.4	6 ± 0	-106.2
1.1.12.01.	Potassium channel KcsA, 14.5 A opening conformer	3fb5	Streptomyces lividans	Bact. Gram-pos plas.	4	8	33.7 ± 0.9	0 ± 0	-115.9
1.1.12.01.	Potassium channel KvAP	2a0l	Aeropyrum pernix	Archaebac.	4	12	29.5 ± 1.1	0 ± 0	-100.0
1.1.12.01.	Voltage gated sodium channel, open conformation	4f4l	Magnetococcus marinus	Bact. Gram-neg inner	4	8	28.2 ± 1.3	1 ± 0	-74.6
1.1.12.01.	Voltage-gated sodium channel NavAb	3rvy	Arcobacter butzleri	Bact. Gram-neg inner	4	24	29.6 ± 0.4	0 ± 0	-216.9
1.1.12.01.	Potassium channel KcsA	1r3j	Streptomyces lividans	Bact. Gram-pos plas.	4	12	34.8 ± 1.2	0 ± 0	-111.0
1.1.12.01.	Potassium channel KcsA, full length, open	3pjs	Streptomyces lividans	Bact. Gram-pos plas.	4	8	31.6 ± 1.2	1 ± 1	-87.3
1.1.12.01.	Potassium channel KcsA, 16 A opening conformer	3fb6	Streptomyces lividans	Bact. Gram-pos plas.	4	8	30.2 ± 1.0	0 ± 0	-86.1
1.1.12.01.	Potassium channel Kv1.2 - Kv2.1. chimera, in membrane-like environment	2r9r	Rattus norvegicus	Eukaryo. plasma	4	28	30.8 ± 0.6	0 ± 0	-252.0
1.1.12.01.	Potassium channel subfamily K member 4	3um7	Homo sapiens	Eukaryo. plasma	2	12	30.8 ± 1.2	3 ± 0	-93.2
1.1.12.01.	Potassium channel Kv1.2. - Kv2.1. chimera	3lnm	Rattus norvegicus	Eukaryo. plasma	4	28	31.1 ± 0.9	0 ± 0	-260.7
1.1.12.01.	Potassium channel KcsA	1s5h	Streptomyces coelicolor	Bact. Gram-pos plas.	4	12	33.7 ± 1.3	0 ± 1	-111.9
1.1.12.01.	Potassium channel KcsA, full-length, closed	3eff	Streptomyces lividans	Bact. Gram-pos plas.	4	12	31.8 ± 1.3	0 ± 0	-107.3
1.1.12.01.	NaK potassium channel, different strain of Bacillus cereus	3ouf	Bacillus cereus	Bact. Gram-pos plas.	4	12	27.9 ± 1.3	0 ± 0	-91.0
1.1.12.01.	Potassium channel KcsA, 20 A opening conformer	3fb8	Streptomyces lividans	Bact. Gram-pos plas.	4	8	29.8 ± 0.4	0 ± 0	-68.2
1.1.12.02.	Kir3.1-prokaryotic Kir channel chimera	2qks	Burkholderia xenovorans	Bact. Gram-neg inner	4	12	30.5 ± 1.4	0 ± 1	-88.6
1.1.12.02.	G protein-activated inward rectifier potassium channel 2 (GIRK2, Kir3.2)	3sya	Mus musculus	Eukaryo. plasma	4	12	34.8 ± 0.7	0 ± 0	-145.5
1.1.12.02.	Potassium channel Kirbac1.1, closed state, refined	2wll	Burkholderia pseudomallei	Bact. Gram-neg inner	4	8	33.4 ± 2.4	0 ± 0	-109.1
1.1.12.02.	G protein-activated inward rectifier potassium channel 2, diff. conf.	3syq	Mus musculus	Eukaryo. plasma	4	8	31.6 ± 0.6	0 ± 0	-107.9
1.1.12.02.	Potassium channel Kv1.2. - Kv2.1. chimera, complex with Charybdotoxin	4jtc	Rattus norvegicus	Eukaryo. plasma	24	4	30.2 ± 0.4	0 ± 0	-247.3
1.1.12.02.	Potassium channel Kirbac3.1, closed conformation	2wlk	Magnetospirillum magnetotacticum	Bact. Gram-neg inner	4	8	29.8 ± 2.4	0 ± 0	-78.7
1.1.12.02.	Potassium channel Kir 2.2	3jyc	Gallus gallus	Eukaryo. plasma	4	12	30.5 ± 1.4	0 ± 1	-119.9
1.1.12.02.	Potassium channel Kirbac3.1, open conformation	3zrs	Magnetospirillum magnetotacticum	Bact. Gram-neg inner	4	12	30.0 ± 1.1	0 ± 0	-85.9
1.1.12.02.	Potassium channel Kir 2.2, complex with pyrophosphate lipid	3spc	Gallus gallus	Eukaryo. plasma	4	8	30.6 ± 1.2	0 ± 0	-120.3
1.1.12.02.	G protein-activated inward rectifier potassium channel 2	4kfm	Mus musculus	Eukaryo. plasma	4	8	33.6 ± 1.2	0 ± 0	-120.7
1.1.12.02.	Potassium channel Kir 2.2, complex with inositol lipid	3spg	Gallus gallus	Eukaryo. plasma	4	8	30.8 ± 1.2	0 ± 0	-109.1
1.1.12.02.	Potassium channel Kirbac1.1, closed state	1p7b	Burkholderia pseudomallei	Bact. Gram-neg inner	4	12	33.1 ± 1.3	0 ± 0	-111.9
1.1.12.03.	TrkH/TrkA potassium transport complex	4j7c	Bacillus subtilis	Bact. Gram-pos plas.	2	16	31.8 ± 1.0	0 ± 0	-165.6
1.1.12.03.	TrkH/TrkA potassium transport complex	4j9u	Vibrio parahaemolyticus	Bact. Gram-neg inner	2	20	29.4 ± 0.7	0 ± 0	-151.9
1.1.12.03.	Potassium uptake protein TrkH	3pjz	Vibrio parahaemolyticus	Bact. Gram-neg inner	2	20	29.7 ± 0.6	1 ± 0	-164.0
1.1.13.01.	Acid-sensitive ion channel, conformation at low pH	3hgc	Gallus gallus	Eukaryo. plasma	3	6	24.1 ± 0.7	0 ± 0	-37.9
1.1.13.01.	Acid-sensing ion channel	2qts	Gallus gallus	Eukaryo. plasma	3	6	36.6 ± 0.9	15 ± 0	-67.8
1.1.13.02.	ATP-gated P2X4 ion channel, closed state	3h9v	Danio rerio	Eukaryo. plasma	3	6	27.6 ± 1.3	0 ± 1	-61.3
1.1.13.02.	ATP-gated P2X4 ion channel, open state	4dw1	Danio rerio	Eukaryo. plasma	3	6	26.8 ± 0.6	0 ± 0	-56.0
1.1.14.01.	Aquaporin-4	3gd8	Homo sapiens	Eukaryo. plasma	4	32	29.8 ± 1.1	0 ± 1	-122.9
1.1.14.01.	Aquaporin-0, alternative packing with lipids	3m9i	Ovis aries	Eukaryo. plasma	4	24	27.6 ± 1.4	0 ± 0	-139.0
1.1.14.01.	Aquaporin-0	2b6o	Ovis aries	Eukaryo. plasma	4	32	31.8 ± 1.4	0 ± 0	-143.3
1.1.14.01.	Aquaporin-1	1j4n	Bos taurus	Eukaryo. plasma	4	32	31.8 ± 1.0	0 ± 0	-129.2
1.1.14.01.	Aquaporin-0	1ymg	Bos taurus	Eukaryo. plasma	4	32	31.3 ± 1.2	0 ± 0	-138.4
1.1.14.01.	Aquaporin-1	1h6i	Homo sapiens	Eukaryo. plasma	4	32	30.8 ± 1.1	0 ± 0	-135.6
1.1.14.01.	Aquaporin Sopip2, closed state	1z98	Spinacia oleracea	Eukaryo. plasma	4	32	28.1 ± 2.2	0 ± 0	-117.2
1.1.14.01.	Aquaporin-5	3d9s	Homo sapiens	Eukaryo. plasma	4	32	30.3 ± 0.9	0 ± 0	-133.3
1.1.14.01.	Aquaporin-4, different conformation of loops with lipids	2zz9	Rattus norvegicus	Eukaryo. plasma	4	28	29.5 ± 0.7	0 ± 0	-115.6
1.1.14.01.	Aquaporin-0, open state	2b6p	Bos taurus	Eukaryo. plasma	4	32	31.1 ± 1.5	0 ± 1	-130.0
1.1.14.01.	Aquaporin Sopip2, open state	2b5f	Spinacia oleracea	Eukaryo. plasma	4	32	29.4 ± 1.1	2 ± 2	-113.0
1.1.14.01.	Aquaporin Z	1rc2	Escherichia coli	Bact. Gram-neg inner	4	32	29.7 ± 1.3	0 ± 0	-118.7
1.1.14.01.	Aquaporin AqpM	3ne2	Archaeoglobus fulgidus	Archaebac.	4	24	31.2 ± 1.3	0 ± 0	-143.5
1.1.14.01.	Aquaporin Sopip2, closed state 2	3cll	Spinacia oleracea	Eukaryo. plasma	4	27	29.8 ± 0.7	0 ± 0	-127.8
1.1.14.01.	Glycerol uptake facilitator	1ldf	Escherichia coli	Bact. Gram-neg inner	4	32	30.1 ± 0.9	0 ± 0	-147.9
1.1.14.01.	Aquaporin AQY1	2w2e	Pichia pastoris	Eukaryo. plasma	4	32	30.2 ± 0.8	0 ± 0	-131.7
1.1.14.01.	Aquaporin AqpM	2f2b	Methanobacterium thermoautotrophicum	Archaebac.	4	32	29.0 ± 0.8	0 ± 0	-129.9
1.1.14.01.	Aquaglyceroporin	3c02	Plasmodium falciparum	Eukaryo. plasma	4	32	30.4 ± 1.3	0 ± 0	-137.4
1.1.14.01.	Aquaporin Z2	3llq	Agrobacterium tumefaciens	Bact. Gram-neg inner	4	32	29.8 ± 0.6	0 ± 0	-134.5
1.1.14.01.	Aquaporin-4	2d57	Rattus norvegicus	Eukaryo. plasma	4	32	29.8 ± 1.1	0 ± 0	-126.2
1.1.14.02.	Formate transporter 1, FocA	3kly	Vibrio cholerae	Bact. Gram-neg inner	5	35	31.4 ± 0.5	1 ± 0	-188.2
1.1.14.02.	Formate transporter 1, FocA	3kcu	Escherichia coli	Bact. Gram-neg inner	5	35	29.9 ± 0.7	0 ± 0	-160.9
1.1.14.02.	Nitrite transporter NirC	4fc4	Salmonella typhimurium	Bact. Gram-neg inner	5	35	33.8 ± 0.0	0 ± 0	-112.5
1.1.14.02.	Formate/nitrite transporter	3tdp	Clostridium difficile	Bact. Gram-pos plas.	5	30	28.4 ± 1.9	0 ± 0	-161.3
1.1.14.02.	Formate transporter	3q7k	Salmonella enterica	Bact. Gram-neg inner	5	30	28.6 ± 0.0	0 ± 0	-148.8
1.1.15.01.	Nicotinic acetylcholine receptor, beta2 subunit, in LDAO micelles	2lm2	Homo sapiens	Eukaryo. plasma	1	4	29.2 ± 1.6	14 ± 2	-48.8
1.1.15.01.	Glycine receptor, alpha1 subunit	1vry	Homo sapiens	Eukaryo. plasma	1	2	23.2 ± 3.7	5 ± 9	-25.3
1.1.15.01.	Nicotinic acetylcholine receptor, closed state	2bg9	Torpedo marmorata	Eukaryo. plasma	5	20	30.1 ± 1.1	3 ± 0	-119.6
1.1.15.01.	Glutamate-gated chloride channel GluCl alpha	3rhw	Caenorhabditis elegans	Eukaryo. plasma	5	20	30.2 ± 0.7	0 ± 0	-107.9
1.1.15.01.	Nicotinic acetylcholine receptor, alpha4 subunit, in LDAO micelles	2lly	Homo sapiens	Eukaryo. plasma	1	4	29.2 ± 1.2	8 ± 1	-49.2
1.1.15.01.	Nicotinic acetylcholine receptor, partially open state	4aq9	Torpedo marmorata	Eukaryo. plasma	5	20	30.8 ± 0.8	2 ± 0	-109.5
1.1.15.01.	Nicotinic acetylcholine receptor, beta2 subunit, in hexafluoroisopropanol/water	2ksr	Homo sapiens	Eukaryo. plasma	1	4	29.1 ± 2.2	16 ± 1	-47.0
1.1.15.02.	Proton-gated ion channel, different conformation	4a97	Erwinia chrysanthemi	Bact. Gram-neg inner	5	40	31.8 ± 0.5	0 ± 0	-125.8
1.1.15.02.	Proton-gated ion channel, different inactive conformation	3uq7	Erwinia chrysanthemi	Bact. Gram-neg inner	5	20	32.0 ± 1.6	0 ± 1	-92.6
1.1.15.02.	Proton-gated ion channel, inactive, complex with acetylcholine	3rqw	Erwinia chrysanthemi	Bact. Gram-neg inner	5	20	29.8 ± 0.4	0 ± 0	-118.8
1.1.15.02.	Proton-gated ion channel, open state	3eam	Gloeobacter violaceus	Bact. Gram-neg inner	5	20	32.7 ± 0.9	0 ± 1	-183.4
1.1.15.02.	Proton-gated ion channel, locally closed	3tlw	Gloeobacter violaceus	Bact. Gram-neg inner	5	20	34.0 ± 1.6	0 ± 0	-190.3
1.1.15.02.	Proton-gated ion channel, inactive conformation	2vl0	Erwinia chrysanthemi	Bact. Gram-neg inner	5	20	31.8 ± 1.3	0 ± 0	-107.6
1.1.16.01.	Glutamate receptor 2	3kg2	Rattus norvegicus	Eukaryo. plasma	4	16	31.8 ± 2.0	0 ± 0	-93.0
1.1.17.01.	Rh-like protein	3b9y	Nitrosomonas europaea	Bact. Gram-neg inner	3	33	29.8 ± 1.3	0 ± 0	-150.1
1.1.17.01.	Ammonium transporter Amt-1	2b2f	Archaeoglobus fulgidus	Archaebac.	3	33	28.9 ± 0.7	0 ± 0	-152.5
1.1.17.01.	Ammonia channel, complex with inhibitory GlnK	2ns1	Escherichia coli	Bact. Gram-neg inner	3	33	29.1 ± 0.7	0 ± 0	-148.7
1.1.17.01.	Rhesus Glycoprotein RhCG	3hd6	Homo sapiens	Eukaryo. plasma	3	36	31.8 ± 0.7	0 ± 0	-174.1
1.1.17.01.	Ammonia Channel	1u7g	Escherichia coli	Bact. Gram-neg inner	3	33	29.8 ± 1.3	0 ± 0	-148.7
1.1.17.02.	Urea transporter 1	4ezc	Bos taurus	Eukaryo. plasma	3	30	31.2 ± 0.6	0 ± 0	-138.8
1.1.17.02.	Urea transporter	3k3f	Desulfovibrio vulgaris	Bact. Gram-neg inner	3	30	29.4 ± 0.8	0 ± 0	-124.4
1.1.18.01.	Mechanosensitive channel MscL	2oar	Mycobacterium tuberculosis	Bact. Gram-pos plas.	5	10	36.1 ± 2.2	0 ± 0	-142.7
1.1.18.01.	Mechanosensitive channel MscL	3hzq	Staphylococcus aureus	Bact. Gram-pos plas.	4	8	20.8 ± 1.2	1 ± 0	-56.9
1.1.19.01.	Mechanosensitive channel protein MscS	3t9n	Thermoanaerobacter tengcongensis	Bact. Gram-pos plas.	7	7	28.0 ± 0.7	0 ± 0	-131.5
1.1.19.01.	Mechanosensitive channel protein MscS, expanded state	2oau	Escherichia coli	Bact. Gram-neg inner	7	14	31.8 ± 0.8	1 ± 1	-171.3
1.1.19.01.	Mechanosensitive channel protein MscS, slightly different conf.	3udc	Thermoanaerobacter tengcongensis	Bact. Gram-pos plas.	7	7	32.2 ± 0.7	0 ± 0	-121.8
1.1.19.01.	Mechanosensitive channel protein MscS, closed state	4hw9	Helicobacter pylori	Bact. Gram-neg inner	7	14	31.6 ± 1.8	0 ± 0	-140.9
1.1.19.01.	Mechanosensitive channel protein MscS, open state	2vv5	Escherichia coli	Bact. Gram-neg inner	7	21	27.8 ± 1.9	0 ± 0	-138.7
1.1.20.01.	Connexin 26 gap junction channel (beta-2 protein)	2zw3	Spodoptera frugiperda	Eukaryo. plasma	6	24	32.2 ± 0.5	0 ± 0	-155.9
1.1.21.01.	CorA magnesium transporter, complete loops	4i0u	Thermotoga maritima	Bact. Gram-neg inner	5	10	30.4 ± 1.1	0 ± 0	-83.4
1.1.21.01.	CorA magnesium transporter, conformation 1	2bbj	Thermotoga maritima	Bact. Gram-neg inner	5	10	29.9 ± 1.0	0 ± 0	-80.8
1.1.21.01.	CorA magnesium transporter, conformation 2	4eeb	Thermotoga maritima	Bact. Gram-neg inner	5	10	30.0 ± 1.0	1 ± 1	-81.6
1.1.21.01.	Magnesium transport protein CorA	4ev6	Methanococcus jannaschii	Archaebac.	5	10	28.4 ± 1.5	0 ± 1	-92.4
1.1.21.01.	CorA magnesium transporter, conformation 3	2iub	Thermotoga maritima	Bact. Gram-neg inner	5	10	28.0 ± 1.2	0 ± 0	-65.7
1.1.22.01.	Pore-forming haemolysin E (HlyE)	2wcd	Escherichia coli	Secreted	12	36	30.8 ± 0.7	0 ± 0	-148.3
1.1.25.01.	Glycerol-3-Phosphate Transporter	1pw4	Escherichia coli	Bact. Gram-neg inner	1	12	31.2 ± 1.4	1 ± 7	-92.5
1.1.25.02.	Lactose permease, conformation 4	2y5y	Escherichia coli	Bact. Gram-neg inner	1	12	31.8 ± 1.3	4 ± 1	-89.0
1.1.25.02.	Lactose permease, conformation 2	2v8n	Escherichia coli	Bact. Gram-neg inner	1	12	31.8 ± 0.8	5 ± 0	-86.4
1.1.25.02.	Lactose permease, conformation 1	2cfq	Escherichia coli	Bact. Gram-neg inner	1	12	31.9 ± 1.1	5 ± 1	-87.9
1.1.25.02.	Lactose Permease, structure at acidic pH	2cfp	Escherichia coli	Bact. Gram-neg inner	1	12	31.1 ± 1.4	2 ± 2	-85.4
1.1.25.02.	Lactose permease, conformation 3	1pv6	Escherichia coli	Bact. Gram-neg inner	1	12	31.8 ± 1.2	5 ± 0	-89.1
1.1.25.03.	Multidrug transporter EmrD	2gfp	Escherichia coli	Bact. Gram-neg inner	1	12	31.6 ± 1.5	9 ± 0	-58.0
1.1.25.04.	L-fucose-proton symporter	3o7q	Escherichia coli	Bact. Gram-neg inner	1	12	30.7 ± 1.3	6 ± 0	-85.3
1.1.25.05.	Bacterial oligopeptide-proton symporter	2xut	Shewanella oneidensis	Bact. Gram-neg inner	1	14	30.9 ± 1.4	10 ± 0	-102.5
1.1.25.06.	D-xylose-proton symporter, conformation 2	4ja3	Escherichia coli	Bact. Gram-neg inner	1	12	29.8 ± 1.0	4 ± 1	-87.6
1.1.25.06.	D-xylose-proton symporter, conformation 3	4ja4	Escherichia coli	Bact. Gram-neg inner	1	12	28.2 ± 1.3	0 ± 0	-82.8
1.1.25.06.	Phosphate transporter	4j05	Acanthamoeba culbertsoni	Eukaryo. plasma	1	12	30.0 ± 0.5	14 ± 0	-84.2
1.1.25.06.	D-xylose-proton symporter, conformation 1	4gc0	Escherichia coli	Bact. Gram-neg inner	1	12	30.2 ± 0.9	1 ± 0	-90.2
1.1.25.07.	Nitrite exporter NarU	4iu9	Escherichia coli	Bact. Gram-neg inner	1	12	31.0 ± 1.2	4 ± 0	-88.1
1.1.25.07.	Nitrate/nitrite exchanger NarK	4jr9	Escherichia coli	Bact. Gram-neg inner	1	12	29.6 ± 1.0	8 ± 0	-86.2
1.1.26.01.	Leucine transporter LeuT, outward-facing substrate-bound conformation	2a65	Aquifex aeolicus	Bact. Gram-neg inner	2	28	29.8 ± 0.5	0 ± 0	-157.9
1.1.26.01.	Leucine transporter LeuT, outward-facing substrate-free conformation	3tt1	Aquifex aeolicus	Bact. Gram-neg inner	2	24	28.2 ± 1.2	0 ± 0	-160.8
1.1.26.01.	Leucine transporter LeuT, inward-facing conformation	3tt3	Aquifex aeolicus	Bact. Gram-neg inner	1	12	27.4 ± 1.6	9 ± 0	-89.1
1.1.26.01.	Leucine transporter LeuT, outward-facing conformation, from bicelles	4fxz	Aquifex aeolicus	Bact. Gram-neg inner	2	24	28.0 ± 0.6	0 ± 0	-144.3
1.1.26.02.	Sodium-hydantoin transporter Mhp1, ligand-bound	2jlo	Mycobacterium liquefaciens	Bact. Gram-pos plas.	1	12	31.2 ± 0.8	15 ± 0	-96.5
1.1.26.02.	Sodium-hydantoin transporter Mhp1, outward-facing conformation	2jln	Mycobacterium liquefaciens	Bact. Gram-pos plas.	1	12	29.8 ± 1.5	16 ± 0	-98.9
1.1.26.02.	Sodium-hydantoin transporter Mhp1, inward-facing conformation	2x79	Mycobacterium liquefaciens	Bact. Gram-pos plas.	1	12	30.7 ± 1.1	13 ± 0	-85.0
1.1.26.03.	Sodium/sugar symporter vSGLT, substrate-free	2xq2	Vibrio parahaemolyticus	Bact. Gram-neg inner	2	30	30.4 ± 0.6	0 ± 0	-162.7
1.1.26.03.	Sodium/sugar symporter vSGLT, substrate-bound	3dh4	Vibrio parahaemolyticus	Bact. Gram-neg inner	2	30	30.0 ± 0.7	0 ± 0	-184.0
1.1.26.04.	Glycine betaine transporter BetP, asymmetric trimer, conformation 2	4doj	Corynebacterium glutamicum	Bact. Gram-pos plas.	3	36	30.0 ± 0.6	0 ± 0	-186.4
1.1.26.04.	L-carnitine/gamma-butyrobetaine antiporter CaiT, substrate-bound	3hfx	Escherichia coli	Bact. Gram-neg inner	3	42	29.8 ± 0.8	0 ± 0	-203.5
1.1.26.04.	L-carnitine/gamma-butyrobetaine antiporter CaiT, open inward-facing conformation	2wsx	Escherichia coli	Bact. Gram-neg inner	3	42	28.6 ± 0.7	7 ± 0	-212.7
1.1.26.04.	L-carnitine/gamma-butyrobetaine antiporter CaiT, open inward-facing conformation	2wsw	Proteus mirabilis	Bact. Gram-neg inner	3	42	29.8 ± 0.5	0 ± 0	-218.9
1.1.26.04.	Glycine betaine transporter BetP, asymmetric trimer, conformation 1	4ain	Corynebacterium glutamicum	Bact. Gram-pos plas.	3	36	29.8 ± 0.6	0 ± 0	-198.8
1.1.26.04.	Glycine betaine transporter BetP, substrate-bound	2wit	Corynebacterium glutamicum	Bact. Gram-pos plas.	3	36	30.4 ± 1.2	0 ± 0	-198.6
1.1.26.04.	Glycine betaine transporter BetP, alternative inward-facing open conformation	3p03	Corynebacterium glutamicum	Bact. Gram-pos plas.	3	36	29.8 ± 0.7	1 ± 0	-160.9
1.1.26.05.	Glutamate/gamma-aminobutyrate antiporter	4dji	Escherichia coli	Bact. Gram-neg inner	1	12	30.0 ± 1.1	10 ± 1	-98.9
1.1.26.05.	Arginine/agmatine antiporter (AdiC), outward-facing conformation	3h5m	Escherichia coli	Bact. Gram-neg inner	2	26	29.0 ± 0.8	0 ± 0	-128.9
1.1.26.05.	Arginine/agmatine transporter (AdiC), intermediate conformation	3ob6	Escherichia coli	Bact. Gram-neg inner	2	24	29.8 ± 1.4	3 ± 1	-158.7
1.1.26.05.	Arginine/agmatine antiporter (AdiC), outward-facing conformation	3hqk	Salmonella enterica	Bact. Gram-neg inner	2	26	29.8 ± 1.0	0 ± 0	-124.6
1.1.26.05.	Amino acid transporter ApcT, inward-facing conformation	3gia	Methanococcus jannaschii	Archaebac.	1	12	29.9 ± 1.4	11 ± 2	-92.1
1.1.26.05.	Arginine/agmatine transporter (AdiC), substrate-bound	3l1l	Escherichia coli	Bact. Gram-neg inner	2	24	28.8 ± 1.4	2 ± 2	-132.0
1.1.26.06.	Uracil transporter UraA	3qe7	Escherichia coli	Bact. Gram-neg inner	1	14	27.7 ± 1.2	16 ± 0	-79.3
1.1.27.01.	Ferrous-iron efflux pump fieF, different conformation	2qfi	Escherichia coli	Bact. Gram-neg inner	2	12	25.0 ± 1.3	1 ± 2	-32.4
1.1.27.01.	Ferrous-iron efflux pump fieF	3h90	Escherichia coli	Bact. Gram-neg inner	2	12	29.6 ± 0.8	0 ± 2	-83.9
1.1.27.01.	Zinc transporter YiiP, inward-facing conformation	3j1z	Shewanella oneidensis	Bact. Gram-neg inner	2	12	28.6 ± 1.2	8 ± 1	-54.4
1.1.28.01.	Multidrug efflux transporter AcrB with YajC subunit , symmetric	2rdd	Escherichia coli	Bact. Gram-neg inner	6	39	28.4 ± 0.5	0 ± 0	-156.2
1.1.28.01.	Multidrug efflux transporter AcrB, asymmetric, complex with ankyrin repeat 1	4dx5	Escherichia coli	Bact. Gram-neg inner	3	36	27.4 ± 0.7	1 ± 0	-181.0
1.1.28.01.	Multidrug efflux transporter AcrB, symmetric	3d9b	Escherichia coli	Bact. Gram-neg inner	3	36	28.4 ± 0.6	0 ± 0	-189.9
1.1.28.01.	Multidrug exporter MexB	2v50	Pseudomonas aeruginosa	Bact. Gram-neg inner	3	36	28.6 ± 1.0	0 ± 1	-167.3
1.1.28.01.	Multidrug efflux transporter AcrB, asymmetric, complex with ankyrin repeat 2	3nog	Escherichia coli	Bact. Gram-neg inner	3	36	29.0 ± 0.5	3 ± 0	-202.9
1.1.28.01.	Multidrug efflux transporter AcrB, asymmetric	2gif	Escherichia coli	Bact. Gram-neg inner	3	36	29.0 ± 0.2	1 ± 0	-187.5
1.1.28.02.	Efflux transporter CusA, complex with CusB, pre-extrusion state	3t56	Escherichia coli	Bact. Gram-neg inner	3	36	30.4 ± 0.6	0 ± 0	-153.7
1.1.28.02.	Efflux transporter CusA, complex with CusB	3ne5	Escherichia coli	Bact. Gram-neg inner	3	36	29.0 ± 0.7	0 ± 0	-165.0
1.1.28.02.	Efflux transporter CusA, apo-protein	3k07	Escherichia coli	Bact. Gram-neg inner	3	33	27.4 ± 1.2	0 ± 0	-166.7
1.1.28.02.	Efflux transporter CusA, Cu(i) complex	3kss	Escherichia coli	Bact. Gram-neg inner	3	33	28.8 ± 0.5	0 ± 0	-147.7
1.1.28.03.	SecDF protein-export membrane protein	3aqp	Thermus thermophilus	Bact. Gram-neg inner	1	12	29.8 ± 0.9	5 ± 1	-93.8
1.1.30.01.	Membrane protein insertase YidC, periplasmic domain	3blc	Escherichia coli	Bact. Gram-neg inner	1	0	6.6 ± 0.5	40 ± 11	-7.0
1.1.31.01.	Tellurite resistance protein tehA homolog	3m73	Haemophilus influenzae	Bact. Gram-neg inner	3	30	29.1 ± 1.4	0 ± 0	-157.4
1.1.32.01.	Proton glutamate symport protein, outward-facing state	2nwl	Pyrococcus horikoshii	Archaebac.	3	39	29.8 ± 1.3	0 ± 0	-202.1
1.1.32.01.	Proton glutamate symport protein, outward-facing state 2	2nww	Pyrococcus horikoshii	Archaebac.	3	36	30.6 ± 0.6	0 ± 0	-200.2
1.1.32.01.	Proton glutamate symport protein, mixed inward/outward trimer	3v8g	Pyrococcus horikoshii	Archaebac.	3	30	29.8 ± 1.0	5 ± 0	-169.4
1.1.32.01.	Proton glutamate symport protein, inward-facing state	3kbc	Pyrococcus horikoshii	Archaebac.	3	30	28.1 ± 0.9	0 ± 1	-158.8
1.1.33.02.	Bile acid sodium symporter ASBT	3zuy	Neisseria meningitidis	Bact. Gram-neg inner	1	10	29.8 ± 1.5	15 ± 2	-82.3
1.1.34.01.	Mitochondrial uncoupling protein 2	2lck	Mus musculus	Mitochon. inner	1	6	30.0 ± 1.2	12 ± 1	-30.3
1.1.34.01.	Mitochondrial ADP-ATP carrier, with carboxyatractyloside	2c3e	Bos taurus	Mitochon. inner	1	6	30.0 ± 1.0	4 ± 2	-44.0
1.1.34.01.	Mitochondrial ADP-ATP carrier	1okc	Bos taurus	Mitochon. inner	1	6	29.5 ± 1.7	14 ± 1	-44.6
1.1.35.01.	Sodium/proton antiporter 1 (NhaA), dimer	3fi1	Escherichia coli	Bact. Gram-neg inner	2	24	28.4 ± 1.6	2 ± 1	-126.7
1.1.35.01.	Sodium/proton antiporter 1 (NhaA)	1zcd	Escherichia coli	Bact. Gram-neg inner	1	14	28.4 ± 1.4	2 ± 2	-78.6
1.1.36.01.	ClC chloride transporter	1ots	Escherichia coli	Bact. Gram-neg inner	2	28	29.7 ± 0.8	0 ± 0	-115.3
1.1.36.01.	ClC chloride transporter	1kpl	Salmonella enterica	Bact. Gram-neg inner	2	28	29.3 ± 0.8	2 ± 1	-128.0
1.1.36.01.	ClC chloride transporter	3org	Cyanidoschyzon merolae	Eukaryo. plasma	2	28	28.7 ± 1.3	0 ± 2	-140.4
1.1.36.01.	ClC chloride transporter	3nd0	Synechocystis sp.	Bact. Gram-neg inner	2	28	29.8 ± 0.7	0 ± 1	-120.9
1.1.38.01.	H+-driven MATE exporter, outward-open, straight conformation	3wbn	Pyrococcus furiosus	Archaebac.	1	12	31.8 ± 1.4	8 ± 0	-88.2
1.1.38.01.	H+-driven MATE exporter, outward-open, "bent" conformation	3vvo	Pyrococcus furiosus	Archaebac.	1	12	31.4 ± 1.1	11 ± 0	-93.1
1.1.38.01.	Na+/drug antiporter NorM, outward-open	4hum	Neisseria gonorrhoeae	Bact. Gram-neg inner	1	12	28.6 ± 1.1	5 ± 1	-54.5
1.1.38.01.	H+-driven MATE exporter, outward-open, with nonpeptide inhibitor	3vvp	Pyrococcus furiosus	Archaebac.	1	12	29.8 ± 1.3	8 ± 0	-79.6
1.1.38.01.	Na+/drug antiporter NorM, outward-open	3mkt	Vibrio cholerae	Bact. Gram-neg inner	1	12	29.8 ± 1.1	9 ± 0	-74.0
1.1.39.01.	Riboflavin transporter RibU	3p5n	Staphylococcus aureus	Bact. Gram-pos plas.	1	6	30.6 ± 1.4	6 ± 4	-53.5
1.1.39.02.	Biotin transporter BioY	4dve	Lactococcus lactis	Bact. Gram-pos plas.	1	6	31.8 ± 1.2	13 ± 1	-71.7
1.1.39.02.	Thiamine transporter protein	3rlb	Lactococcus lactis	Bact. Gram-pos plas.	1	6	30.8 ± 1.8	9 ± 1	-60.4
1.1.39.03.	Energy-coupling factor transporter EcfA, conformation 1	4hzu	Lactobacillus brevis	Bact. Gram-pos plas.	2	7	29.7 ± 1.6	13 ± 1	-64.8
1.1.39.03.	Energy-coupling factor transporter EcfA, conformation 2	4huq	Bacillus brevis	Bact. Gram-pos plas.	7	7	29.8 ± 0.7	14 ± 0	-76.0
1.1.41.01.	Magnesium ion transporter-E (MgtE)	2yvx	Thermus thermophilus	Bact. Gram-neg inner	2	10	31.1 ± 0.9	0 ± 0	-69.2
1.1.43.01.	Saccharide transporter component, EIIC (ChbC)	3qnq	Bacillus cereus	Bact. Gram-pos plas.	2	20	29.6 ± 1.0	1 ± 0	-140.6
1.1.44.01.	Disulfide bond formation protein B, conformation 1	2k74	Escherichia coli	Bact. Gram-neg inner	1	4	29.7 ± 2.4	26 ± 1	-50.2
1.1.44.01.	DsbB - DsbA complex, conformation 2	2zup	Escherichia coli	Bact. Gram-neg inner	1	4	24.2 ± 2.9	3 ± 8	-18.3
1.1.44.01.	Disulfide bond formation protein B, conformation 3	2zuq	Escherichia coli	Bact. Gram-neg inner	1	4	27.9 ± 3.1	27 ± 1	-36.6
1.1.44.01.	DsbB-DsbA complex, conformation 3	2leg	Escherichia coli	Bact. Gram-neg inner	1	4	30.6 ± 1.7	34 ± 2	-36.3
1.1.44.01.	DsbB - DsbA complex, conformation 1	2hi7	Escherichia coli	Bact. Gram-neg inner	1	4	24.3 ± 3.0	30 ± 0	-34.9
1.1.44.01.	Disulfide bond formation protein B, conformation 2	2ltq	Escherichia coli	Bact. Gram-neg inner	1	4	28.4 ± 1.5	26 ± 0	-36.5
1.1.44.01.	DsbB - DsbA complex, conformation 4	3e9j	Escherichia coli	Bact. Gram-neg inner	1	4	26.8 ± 1.5	31 ± 1	-27.1
1.1.46.01.	MerF bacterial mercury uptake transporter	2lj2	Morganella morganii	Bact. Gram-neg inner	1	2	28.8 ± 2.4	19 ± 1	-37.9
1.1.47.01.	Sensor protein kdpD	2ksf	Escherichia coli	Bact. Gram-neg inner	1	4	26.2 ± 4.0	45 ± 1	-27.9
1.1.47.01.	Aerobic respiration control sensor protein acrB	2ksd	Escherichia coli	Bact. Gram-neg inner	1	2	27.9 ± 2.8	9 ± 1	-33.6
1.1.47.01.	Sensor protein qseC	2kse	Escherichia coli	Bact. Gram-neg inner	1	2	31.3 ± 2.5	19 ± 0	-35.7
1.1.48.01.	Putative sulfate permease CysZ	3tx3	Idiomarina loihiensis	Bact. Gram-neg inner	1	6	29.8 ± 0.6	17 ± 4	-49.5
1.1.49.01.	ATP-dependent zinc metalloprotease FtsH	1lv7	Escherichia coli	Bact. Gram-neg inner	1	0	2.1 ± 1.0	80 ± 11	-4.3
1.1.49.01.	ATP-dependent zinc metalloprotease FtsH	3kds	Thermotoga maritima	Bact. Gram-neg inner	6	0	2.2 ± 0.4	90 ± 0	-12.8
1.1.50.01.	Particulate methane monooxygenase, different structure	3rgb	Methylococcus capsulatus	Bact. Gram-neg inner	9	39	28.2 ± 0.6	0 ± 0	-204.9
1.1.50.01.	Particulate methane monooxygenase	3rfr	Methylocystis sp.	Bact. Gram-neg inner	10	39	29.8 ± 0.5	0 ± 0	-198.1
1.1.50.01.	Particulate methane monooxygenase	1yew	Methylococcus capsulatus	Bact. Gram-neg inner	9	42	28.2 ± 0.7	0 ± 0	-188.5
1.1.50.01.	Particulate methane monooxygenase	3chx	Methylosinus trichosporium	Bact. Gram-neg inner	10	30	29.8 ± 0.4	0 ± 0	-152.0
1.1.51.01.	Vitamin K epoxide reductase	3kp9	Synechococcus sp.	Bact. Gram-neg inner	1	5	29.8 ± 1.6	0 ± 0	-45.1
1.1.52.01.	Oligosaccharyltransferase PglB	3rce	Campylobacter lari	Bact. Gram-neg inner	1	13	28.8 ± 0.9	8 ± 0	-89.6
1.1.53.01.	Integral Membrane Methyltransferase	4a2n	Methanosarcina acetivorans	Archaebac.	1	5	30.6 ± 1.2	10 ± 2	-58.3
1.1.54.01.	Diacylglycerol kinase (DAGK)	3ze5	Escherichia coli	Bact. Gram-neg inner	3	9	29.8 ± 0.9	2 ± 1	-72.5
1.1.54.01.	Diacylglycerol kinase (DAGK), NMR model	2kdc	Escherichia coli	Bact. Gram-neg inner	3	9	25.5 ± 1.8	0 ± 0	-39.9
1.1.55.01.	Bacterial polysaccharide co-polymerase FepE	3b8n	Escherichia coli	Bact. Gram-neg inner	9	0	1.6 ± 0.1	1 ± 0	-20.3
1.1.56.01.	Glycerol phosphate lipoteichoic acid synthase 2	2w8d	Bacillus subtilis	Bact. Gram-pos plas.	1	0	0.0 ± 6.0	83 ± 58	-1.6
1.1.56.01.	Glycerol phosphate lipoteichoic acid synthase	2w5q	Staphylococcus aureus	Bact. Gram-pos plas.	1	0	0.4 ± 3.6	82 ± 11	-2.5
1.1.56.01.	Steryl-sulfatase	1p49	Homo sapiens	Endoplasm. reticulum	1	2	29.6 ± 1.1	23 ± 0	-34.6
1.1.57.01.	Peptidase A24B, FlaK domain protein	3s0x	Methanococcus maripaludis	Archaebac.	1	6	31.8 ± 1.6	40 ± 2	-67.7
1.1.57.02.	Intramembrane aspartate protease	4hyg	Methanoculleus marisnigri	Archaebac.	3	27	31.8 ± 0.3	0 ± 0	-172.7
1.1.58.01.	Site-2 protease (S2P) metalloprotease	3b4r	Methanococcus jannaschii	Archaebac.	1	6	29.9 ± 1.4	23 ± 0	-65.0
1.1.59.01.	Membrane protease specific for a stomatin homolog, monomer	3bpp	Pyrococcus horikoshii	Archaebac.	1	0	4.0 ± 0.4	82 ± 5	-6.3
1.1.59.01.	Membrane protease specific for a stomatin homolog, dimer	3viv	Pyrococcus horikoshii	Archaebac.	2	0	4.5 ± 0.4	88 ± 9	-9.5
1.1.59.01.	ATP-dependent Clp protease proteolytic subunit 1	2cby	Mycobacterium tuberculosis	Bact. Gram-pos plas.	7	0	3.2 ± 0.0	89 ± 0	-17.0
1.1.60.01.	Protease GlpG, conformation 1	2xtv	Escherichia coli	Bact. Gram-neg inner	1	6	28.8 ± 1.6	14 ± 1	-61.1
1.1.60.01.	Protease GlpG, complex with inhibitor, conformation 3	3ubb	Escherichia coli	Bact. Gram-neg inner	1	6	29.8 ± 1.3	21 ± 1	-65.3
1.1.60.01.	Protease GlpG	2nr9	Haemophilus influenzae	Bact. Gram-neg inner	1	6	28.2 ± 1.6	13 ± 3	-52.0
1.1.60.01.	Protease GlpG, conformation 2	2nrf	Escherichia coli	Bact. Gram-neg inner	1	6	27.6 ± 1.5	13 ± 2	-45.9
1.1.60.01.	Protease GlpG, conformation 3	2irv	Escherichia coli	Bact. Gram-neg inner	1	6	28.2 ± 1.3	23 ± 5	-48.1
1.1.60.01.	Protease GlpG, crystallographic trimer	4h1d	Escherichia coli	Bact. Gram-neg inner	3	18	27.0 ± 0.1	2 ± 0	-108.7
1.1.60.01.	Protease GlpG, complex with inhibitor, conformation 1	2xow	Escherichia coli	Bact. Gram-neg inner	1	6	29.0 ± 1.7	15 ± 2	-59.0
1.1.60.01.	Protease GlpG, complex with inhibitor, conformation 2	3zeb	Escherichia coli	Bact. Gram-neg inner	1	6	28.4 ± 1.3	12 ± 0	-64.0
1.1.61.01.	Microsomal glutathione S-transferase 1	2h8a	Rattus norvegicus	Endoplasm. reticulum	3	12	29.7 ± 0.7	0 ± 1	-47.7
1.1.61.01.	Microsomal prostaglandin E synthase 1	3dww	Homo sapiens	Endoplasm. reticulum	3	12	31.9 ± 1.1	2 ± 1	-97.3
1.1.61.01.	Microsomal prostaglandin E synthase 1, different conformation	4al0	Homo sapiens	Eukaryo. plasma	3	12	28.8 ± 1.0	0 ± 1	-79.7
1.1.61.01.	FLAP protein (5-lipoxygenase activator)	2q7r	Homo sapiens	Endoplasm. reticulum	3	12	30.3 ± 1.3	0 ± 1	-70.8
1.1.61.01.	Leukotriene C4 synthase	2uuh	Homo sapiens	Endoplasm. reticulum	3	12	29.4 ± 1.1	0 ± 0	-55.2
1.1.62.01.	Diguanylate cyclase/phosphodiesterase	3pjv	Pseudomonas fluorescens	Bact. Gram-neg inner	5	0	4.6 ± 1.5	79 ± 4	-6.6
1.1.63.01.	Type 1 signal peptidase, complex with inhibitor	1b12	Escherichia coli	Bact. Gram-neg inner	1	0	5.4 ± 1.8	88 ± 7	-5.1
1.1.63.01.	Type 1 signal peptidase, apo-enzyme	1kn9	Escherichia coli	Bact. Gram-neg inner	1	0	3.4 ± 1.4	80 ± 6	-7.8
1.1.63.01.	Signal peptidase I	3iiq	Escherichia coli	Bact. Gram-neg inner	2	0	4.3 ± 0.5	57 ± 2	-10.2
1.1.63.01.	Type 1 signal peptidase, complex with lipopeptide inhibitor	1t7d	Escherichia coli	Bact. Gram-neg inner	1	0	3.9 ± 1.0	65 ± 11	-7.6
1.1.64.01.	Sodium/calcium exchanger	3v5u	Methanococcus jannaschii	Archaebac.	1	10	29.8 ± 0.9	3 ± 0	-78.4
1.1.64.01.	Vacuolar calcium ion transporter	4k1c	Saccharomyces cerevisiae	Vacuole	1	11	29.8 ± 1.0	3 ± 0	-87.5
1.1.64.01.	Sodium/calcium exchanger, different conformation	3v5s	Methanococcus jannaschii	Archaebac.	1	10	29.6 ± 1.6	1 ± 2	-75.1
1.1.65.01.	Concentrative nucleoside transporter	3tij	Vibrio cholerae	Bact. Gram-neg inner	3	27	27.0 ± 0.5	0 ± 0	-155.2
1.1.66.01.	K(+)-stimulated pyrophosphate-energized sodium pump, state1	4av3	Thermotoga maritima	Bact. Gram-neg inner	2	32	29.8 ± 0.7	0 ± 0	-182.5
1.1.66.01.	Proton-translocating pyrophosphatase	4a01	Vigna radiata (Mung bean)	Vacuole	2	32	32.0 ± 0.8	0 ± 0	-189.3
1.1.66.01.	K(+)-stimulated pyrophosphate-energized sodium pump, state2	4av6	Thermotoga maritima	Bact. Gram-neg inner	2	32	29.8 ± 0.8	0 ± 0	-173.1
1.1.67.01.	Transmembrane proteins 14A	2lop	Homo sapiens	Mitochon. inner	1	3	28.8 ± 2.0	23 ± 1	-35.5
1.1.67.01.	Transmembrane protein 14C	2los	Homo sapiens	Mitochon. inner	1	3	26.8 ± 0.4	0 ± 2	-18.5
1.1.68.01.	Transmembrane protein 141	2lor	Homo sapiens	Undefined	1	2	24.4 ± 4.0	21 ± 0	-22.2
1.1.69.01.	HIG1 domain family member 1A	2lom	Homo sapiens	Eukaryo. plasma	1	2	22.0 ± 5.0	1 ± 1	-27.3
1.1.69.01.	HIG1 domain family member 1B	2lon	Homo sapiens	Eukaryo. plasma	1	2	22.4 ± 1.2	19 ± 0	-13.7
1.1.70.01.	CAAX prenyl protease 1 homolog	4aw6	Homo sapiens	Endoplasm. reticulum	1	7	30.8 ± 1.3	13 ± 1	-75.9
1.1.70.01.	CaaX Protease Ste24p	4il3	Saccharomyces mikatae	Endoplasm. reticulum	1	7	29.8 ± 1.4	8 ± 0	-63.3
1.1.71.01.	SidF, inhibitor of growth family, member 3	4fyg	Legionella pneumophila	Vacuole	1	0	8.1 ± 3.3	81 ± 10	-3.9
1.1.72.01.	Dicarboxylate/sodium symporter NadC	4f35	Vibrio cholerae	Bact. Gram-neg inner	2	28	27.8 ± 0.2	1 ± 0	-82.5
1.1.73.01.	Outer membrane complex of type IV secretion system (VirB7/VirB9/VirB10 complex)	3jqo	Escherichia coli	Bact. Gram-neg outer	14	14	22.6 ± 0.6	0 ± 0	-67.4
1.1.73.01.	TrbI protein	2bhv	Helicobacter pylori	Bact. Gram-neg outer	1	0	3.1 ± 1.3	42 ± 11	-6.4
1.1.74.01.	Calcium release-activated calcium channel protein 1	4hkr	Drosophila melanogaster	Eukaryo. plasma	6	24	30.0 ± 1.6	0 ± 0	-105.2
1.1.75.01.	Sec-independent protein translocase TatC	4b4a	Aquifex aeolicus	Bact. Gram-neg inner	1	6	30.4 ± 1.2	17 ± 0	-51.7
1.1.75.02.	Sec-independent protein translocase TatA	2l16	Bacillus subtilis	Bact. Gram-pos plas.	1	1	27.6 ± 2.9	10 ± 1	-27.9
1.1.75.02.	Sec-independent protein translocase TatA	2lzr	Escherichia coli	Bact. Gram-neg inner	1	1	29.2 ± 1.8	26 ± 2	-29.1
1.1.75.02.	Sec-independent protein translocase TatA, nonamer model	2lzs	Escherichia coli	Bact. Gram-neg inner	9	9	29.2 ± 1.8	26 ± 2	-29.1
1.1.76.01.	Acid-activated urea channel	3ux4	Helicobacter pylori	Bact. Gram-neg inner	6	36	30.0 ± 0.5	0 ± 0	-190.2
1.1.77.01.	Cellulose-conducting channel	4hg6	Rhodobacter sphaeroides	Bact. Gram-neg inner	2	9	30.0 ± 1.3	17 ± 0	-85.0
1.1.78.01.	Reticulon-4	2ko2	Mus musculus	Endoplasm. reticulum	1	0	2.5 ± 0.3	83 ± 1	-6.2
1.2.01.01.	Insulin-like growth factor 1 receptor	1p4o	Homo sapiens	Eukaryo. plasma	1	0	2.4 ± 1.0	37 ± 11	-5.1
1.2.01.01.	Receptor tyrosine kinase EphA2	2k9y	Homo sapiens	Eukaryo. plasma	2	2	31.8 ± 3.2	12 ± 14	-32.1
1.2.01.01.	Macrophage colony-stimulating factor 1 receptor	3bea	Homo sapiens	Eukaryo. plasma	1	0	2.9 ± 1.5	54 ± 19	-4.2
1.2.01.01.	Receptor tyrosine kinase erbB-2, dimer	2jwa	Homo sapiens	Eukaryo. plasma	2	2	31.9 ± 2.9	13 ± 9	-46.6
1.2.01.01.	Receptor tyrosine-protein kinase erbB-3, peptide 640-670	2l9u	Homo sapiens	Eukaryo. plasma	2	2	33.8 ± 2.4	16 ± 5	-44.6
1.2.01.01.	Focal adhesion kinase 1	2j0k	Gallus gallus	Eukaryo. plasma	1	0	5.0 ± 2.1	36 ± 2	-4.1
1.2.01.01.	Receptor tyrosine-protein kinase erbB-3, extracellular domains	1m6b	Homo sapiens	Eukaryo. plasma	1	0	2.0 ± 1.6	45 ± 5	-3.9
1.2.01.01.	Receptor tyrosine kinase EphA1	2k1k	Homo sapiens	Eukaryo. plasma	2	2	30.2 ± 1.5	0 ± 5	-43.3
1.2.01.01.	Receptor tyrosine-protein kinase erbB-2	1n8y	Rattus norvegicus	Eukaryo. plasma	1	0	3.4 ± 3.0	53 ± 5	-4.2
1.2.01.01.	Fibroblast growth factor receptor 2 complex	3oj2	Homo sapiens	Secreted	6	0	2.0 ± 0.4	81 ± 3	-5.4
1.2.01.01.	Receptor tyrosine-protein kinase erbB-4, peptide 642-685	2l2t	Homo sapiens	Eukaryo. plasma	2	2	32.4 ± 1.5	4 ± 2	-50.4
1.2.01.01.	Platelet-derived growth factor receptor beta, 526-563	2l6w	Homo sapiens	Eukaryo. plasma	2	2	34.8 ± 0.8	18 ± 1	-40.9
1.2.01.01.	Epidermal growth factor receptor, erbB-1, homodimer (642-697)	2m20	Homo sapiens	Eukaryo. plasma	2	2	34.0 ± 3.0	0 ± 3	-52.5
1.2.01.01.	Receptor tyrosine kinase erbB-2, complex with EGF receptor	2ks1	Homo sapiens	Eukaryo. plasma	2	2	32.0 ± 2.5	15 ± 5	-50.6
1.2.01.01.	Receptor tyrosine kinase erbB-2	1iij	Rattus norvegicus	Eukaryo. plasma	1	1	31.8 ± 2.8	27 ± 2	-31.8
1.2.02.01.	Zeta-zeta dimer of T cell receptor	2hac	Homo sapiens	Eukaryo. plasma	2	2	31.9 ± 2.3	7 ± 10	-43.2
1.2.03.01.	T-cell surface glycoprotein CD4	2klu	Homo sapiens	Eukaryo. plasma	1	1	31.8 ± 2.6	12 ± 7	-23.7
1.2.03.02.	Hepatitis A virus cellular receptor 2 homolog	3kaa	Mus musculus	Eukaryo. plasma	1	0	2.8 ± 2.0	55 ± 16	-5.5
1.2.03.02.	T-cell immunoglobulin and mucin domain-containing protein 2	2or7	Mus musculus	Eukaryo. plasma	1	0	0.9 ± 0.7	54 ± 6	-3.3
1.2.03.02.	Hepatitis A virus cellular receptor 1 homolog	2or8	Mus musculus	Eukaryo. plasma	1	0	4.2 ± 2.4	51 ± 16	-3.9
1.2.03.02.	Cytotoxic T-lymphocyte protein 4	1dqt	Mus musculus	Eukaryo. plasma	1	0	3.4 ± 1.6	64 ± 4	-5.3
1.2.03.02.	Sialoadhesin	1url	Mus musculus	Eukaryo. plasma	2	0	3.7 ± 1.8	83 ± 12	-4.0
1.2.03.02.	T-cell-specific surface glycoprotein CD28	1yjd	Homo sapiens	Eukaryo. plasma	1	0	4.5 ± 0.6	46 ± 11	-3.6
1.2.03.02.	SLAM family member 6	2if7	Homo sapiens	Eukaryo. plasma	3	0	2.0 ± 3.3	88 ± 11	-7.1
1.2.03.02.	T-cell immunoglobulin and mucin domain-containing protein 4	3bib	Mus musculus	Eukaryo. plasma	1	0	3.2 ± 1.9	41 ± 7	-4.6
1.2.03.03.	Myelin protein P0	3oai	Homo sapiens	Eukaryo. plasma	1	0	2.2 ± 1.2	72 ± 6	-5.8
1.2.03.03.	Myelin protein P0	1neu	Rattus norvegicus	Eukaryo. plasma	1	0	5.4 ± 1.8	70 ± 8	-6.6
1.2.03.04.	Leukocyte immunoglobulin-like receptor subfamily B member 4	3p2t	Homo sapiens	Eukaryo. plasma	1	0	1.7 ± 0.4	84 ± 5	-5.9
1.2.03.05.	Prolactin receptor	3nce	Homo sapiens	Eukaryo. plasma	2	0	3.4 ± 1.5	68 ± 2	-5.7
1.2.03.07.	Netrin receptor UNC5B	3g5b	Rattus norvegicus	Eukaryo. plasma	1	0	1.9 ± 2.5	90 ± 14	-8.5
1.2.03.07.	Cell adhesion molecule complex	3n1f	Homo sapiens	Eukaryo. plasma	2	0	5.2 ± 0.9	59 ± 4	-5.7
1.2.04.01.	Integrin alpha-1	2l8s	Homo sapiens	Eukaryo. plasma	1	1	32.0 ± 3.7	40 ± 1	-34.5
1.2.04.01.	Integrin alpha-IIb, cytoplasmic domain	1s4w	Homo sapiens	Eukaryo. plasma	1	0	2.9 ± 0.3	69 ± 3	-9.1
1.2.04.01.	Integrin alpha-IIb, complex with integrin beta-3	2knc	Homo sapiens	Eukaryo. plasma	2	2	34.8 ± 1.4	13 ± 5	-46.2
1.2.04.01.	Integrin beta-3, cytoplasmic domain	1s4x	Homo sapiens	Eukaryo. plasma	1	0	6.9 ± 1.0	18 ± 10	-5.8
1.2.04.01.	Integrin beta-3/alpha-V complex	3ije	Homo sapiens	Eukaryo. plasma	2	0	6.1 ± 2.1	13 ± 14	-9.0
1.2.04.01.	Integrin beta-3, cytoplasmic domain, monophosphorylated (747pY)	2ljd	Homo sapiens	Eukaryo. plasma	1	0	8.1 ± 0.6	44 ± 4	-7.6
1.2.04.01.	Integrin beta-3, cytoplasmic domain, biphosphorylated (747pY, 759pY)	2lje	Homo sapiens	Eukaryo. plasma	1	0	4.0 ± 0.5	74 ± 2	-7.0
1.2.04.01.	Integrin alpha-IIb, transmembrane helix	2k1a	Homo sapiens	Eukaryo. plasma	1	1	34.4 ± 2.6	17 ± 6	-36.9
1.2.04.01.	Integrin beta-3, cytoplasmic domain, monophosphorylated (747pY)	2ljf	Homo sapiens	Eukaryo. plasma	1	0	0.6 ± 1.6	62 ± 14	-1.8
1.2.04.01.	Integrin alpha-IIb, complex with integrin beta-3	2k9j	Homo sapiens	Eukaryo. plasma	2	2	36.4 ± 3.3	20 ± 1	-56.4
1.2.04.01.	Integrin beta-3, transmembrane helix	2rmz	Homo sapiens	Eukaryo. plasma	1	1	30.0 ± 3.6	49 ± 2	-36.0
1.2.04.01.	Integrin beta-1, complex with talin-2	3g9w	Homo sapiens	Eukaryo. plasma	2	0	8.7 ± 2.5	83 ± 6	-6.6
1.2.05.01.	Toll-like receptor 4 complex	2z64	Mus musculus	Eukaryo. plasma	2	0	1.1 ± 3.1	51 ± 19	-6.3
1.2.05.01.	Internalin C	1xeu	Listeria monocytogenes	Bact. Gram-pos plas.	1	0	2.9 ± 1.3	81 ± 0	-4.1
1.2.06.01.	Spore surface protein Bcla	1wck	Bacillus anthracis	Bact. Gram-pos plas.	3	0	3.3 ± 0.2	8 ± 5	-8.9
1.2.06.01.	Tumor necrosis factor ligand superfamily member 4	2hew	Mus musculus	Eukaryo. plasma	3	0	1.7 ± 0.3	90 ± 0	-7.9
1.2.07.01.	Protein jagged-1	2vj2	Homo sapiens	Eukaryo. plasma	1	0	3.4 ± 1.8	84 ± 8	-5.8
1.2.07.01.	Protein spitz	3ca7	Drosophila melanogaster	Endoplasm. reticulum	1	0	3.3 ± 2.8	87 ± 3	-4.3
1.2.08.01.	TYRO protein tyrosine kinase-binding protein, homodimer	2l34	Homo sapiens	Eukaryo. plasma	2	2	31.8 ± 3.0	14 ± 10	-36.0
1.2.08.01.	TYRO protein tyrosine kinase-binding protein, heterotrimer	2l35	Homo sapiens	Eukaryo. plasma	2	3	31.6 ± 3.2	20 ± 5	-40.3
1.2.09.01.	Stannin	1zza	Homo sapiens	Mitochon. outer	1	1	30.0 ± 2.0	13 ± 2	-25.2
1.2.10.01.	Glycophorin A	1afo	Homo sapiens	Eukaryo. plasma	2	2	31.9 ± 2.8	5 ± 6	-43.5
1.2.11.01.	Capsid protein G8P	1ifi	Bacteriophage fd	Secreted	15	15	36.8 ± 0.2	0 ± 0	-69.8
1.2.11.01.	Capsid protein G8P	1ifl	Bacteriophage IKe	Secreted	10	10	30.8 ± 0.8	0 ± 0	-93.6
1.2.11.01.	Capsid protein G8P	1ifk	Bacteriophage If1	Secreted	15	15	31.8 ± 0.7	0 ± 0	-83.5
1.2.11.02.	Capsid protein G8P	2cps	Bacteriophage M13	Viral	1	1	30.8 ± 3.1	15 ± 3	-19.9
1.2.11.02.	Capsid protein G8P, monomer	2xkm	Bacteriophage Pf1	Secreted	1	1	29.2 ± 4.6	34 ± 1	-23.0
1.2.11.02.	Capsid protein G8P	2ifo	Bacteriophage Xf	Secreted	12	12	32.2 ± 1.9	16 ± 3	-58.4
1.2.11.02.	Capsid protein G8P	1ifp	Bacteriophage Pf3	Secreted	12	12	34.2 ± 0.1	6 ± 6	-57.6
1.2.11.02.	Capsid protein G8P	1ql1	Bacteriophage Pf1	Secreted	12	12	31.1 ± 1.6	10 ± 0	-55.9
1.2.11.02.	Capsid protein G8P	1hgz	Bacteriophage PH75	Secreted	15	15	29.2 ± 2.3	8 ± 7	-46.5
1.2.12.01.	Fimbrial protein, type IV pilin, monomer	2pil	Neisseria gonorrhoeae	Bact. Gram-neg inner	1	1	30.8 ± 5.7	21 ± 5	-24.9
1.2.12.01.	Fimbrial protein	3sok	Dichelobacter nodosus (Bacteroides nodosus)	Bact. Gram-neg inner	1	1	29.8 ± 3.9	18 ± 5	-25.0
1.2.12.01.	Fimbrial protein, type IV pilin, assembly	2hil	Neisseria gonorrhoeae	Bact. Gram-neg inner	18	1	29.6 ± 3.0	13 ± 1	-15.9
1.2.12.01.	Fimbrial protein, monomer	1oqw	Pseudomonas aeruginosa	Bact. Gram-neg inner	1	1	29.8 ± 3.0	31 ± 8	-28.9
1.2.13.01.	Intrinsic membrane protein PufX	2ita	Rhodobacter sphaeroides	Bact. Gram-neg inner	1	1	32.2 ± 5.1	33 ± 1	-22.8
1.2.14.01.	Transforming growth factor beta receptor type 3	3qw9	Rattus norvegicus	Eukaryo. plasma	2	0	3.1 ± 0.3	87 ± 4	-9.9
1.2.15.02.	Signal recognition particle receptor	1nrj	Saccharomyces cerevisiae	Endoplasm. reticulum	2	0	3.9 ± 1.4	82 ± 11	-5.5
1.2.16.01.	Pulmonary surfactant-associated protein C	1spf	Sus scrofa	Secreted	1	1	31.7 ± 3.3	21 ± 0	-32.0
1.2.17.01.	Complexin/SNARE complex	1kil	Rattus norvegicus	Eukaryo. plasma	5	0	4.0 ± 2.0	15 ± 14	-3.4
1.2.17.01.	Vesicle-associated membrane protein 2	2kog	Rattus norvegicus	Eukaryo. plasma	1	1	34.8 ± 1.7	27 ± 1	-33.7
1.2.17.01.	SNARE complex (syntaxin 1A, SNAP-25 and synaptobrevin 2)	3hd7	Rattus norvegicus	Eukaryo. plasma	2	2	28.5 ± 1.9	3 ± 7	-29.3
1.2.17.01.	Vesicle-associated membrane protein complex	2nps	Mus musculus	Golgi	4	0	5.6 ± 2.2	68 ± 4	-5.6
1.2.17.02.	Synaptobrevin homolog 1	1iou	Saccharomyces cerevisiae	Eukaryo. plasma	1	0	3.4 ± 1.1	79 ± 12	-6.0
1.2.17.02.	Synaptobrevin homolog YKT6	3kyq	Rattus norvegicus	Vesicle	1	0	2.5 ± 2.0	53 ± 8	-4.9
1.2.17.03.	Syntaxin-1	2xhe	Monosiga brevicollis (Choanoflagellate)	Undefined	2	0	4.1 ± 2.3	78 ± 3	-5.3
1.2.18.01.	Sortase B	1rz2	Bacillus anthracis	Bact. Gram-pos plas.	1	0	3.0 ± 0.6	82 ± 6	-5.8
1.2.18.01.	Putative sortase	2wts	Streptococcus pneumoniae	Bact. Gram-pos plas.	1	0	5.1 ± 1.0	20 ± 3	-4.6
1.2.19.01.	Mitochondrial import receptor subunit TOM20, 51-145, with presequence peptide	1om2	Rattus norvegicus	Mitochon. outer	2	0	2.9 ± 2.7	76 ± 7	-4.8
1.2.19.01.	Mitochondrial import receptor subunit TOM20, 59-126, with presequence peptide	3awr	Rattus norvegicus	Mitochon. outer	2	0	5.0 ± 2.6	32 ± 7	-4.1
1.2.20.01.	Mycobacterial protein Rv1761c	2k3m	Mycobacterium tuberculosis	Bact. Gram-pos plas.	1	1	23.8 ± 2.1	11 ± 3	-10.2
1.2.21.01.	BNip3 transmembrane domain homodimer	2ka2	Homo sapiens	Mitochon. outer	2	2	30.8 ± 1.8	4 ± 2	-29.2
1.2.21.01.	BNip3 transmembrane domain homodimer, first alternative structure	2ka1	Homo sapiens	Mitochon. outer	2	2	31.8 ± 2.3	24 ± 8	-34.9
1.2.21.01.	BNip3 transmembrane domain homodimer, second alternative structure	2j5d	Homo sapiens	Mitochon. outer	2	2	30.8 ± 2.5	12 ± 0	-35.8
1.2.22.01.	Activator of apoptosis harakiri, transmembrane helix	2l5b	Homo sapiens	Mitochon. outer	1	1	29.8 ± 0.9	14 ± 11	-11.9
1.2.22.01.	Activator of apoptosis harakiri, cytosolic helix	2l58	Homo sapiens	Mitochon. outer	1	0	2.4 ± 4.0	88 ± 0	-8.5
1.2.22.01.	Apoptosis regulator Bcl-2	1g5m	Homo sapiens	Mitochon. outer	1	0	4.2 ± 1.4	33 ± 11	-6.6
1.2.22.01.	Bcl-2-like protein 1, complex with alpha-beta-foldamer	4a1u	Homo sapiens	Mitochon. outer	1	0	5.8 ± 0.3	26 ± 5	-5.7
1.2.22.01.	Fatty acid amide hydrolase	1mt5	Rattus norvegicus	Endoplasm. reticulum	2	0	11.1 ± 0.2	89 ± 0	-21.9
1.2.23.01.	M2 proton channel of Influenza A, closed state	3lbw	Influenza virus	Viral	4	4	31.1 ± 1.7	7 ± 10	-50.5
1.2.23.01.	M2 proton channel of Influenza A, open state, ligand-free	3bkd	Influenza virus	Viral	4	4	27.1 ± 1.8	3 ± 1	-55.0
1.2.23.01.	M2 proton channel of Influenza A, open state, complex with amantadine	3c9j	Influenza virus	Viral	4	4	29.4 ± 1.4	2 ± 3	-65.6
1.2.23.01.	M2 proton channel of Influenza A, closed state, NMR	2rlf	Influenza virus	Viral	4	4	34.3 ± 2.0	3 ± 1	-67.6
1.2.23.01.	M2 proton channel of Influenza A, closed state, V27A mutant	2kwx	Influenza virus	Viral	4	4	33.4 ± 1.9	2 ± 3	-63.4
1.2.23.01.	M2 proton channel, influenza A and B hydrid	2ljb	Influenza virus	Viral	4	4	31.6 ± 1.6	1 ± 1	-51.3
1.2.23.01.	M2 proton channel of Influenza B	2kix	Influenza virus	Viral	4	4	31.8 ± 1.2	2 ± 3	-64.4
1.2.23.01.	M2 proton channel, influenza A and B hydrid, complex with rimantadine	2ljc	Influenza virus	Viral	4	4	30.6 ± 1.8	9 ± 2	-44.9
1.2.23.01.	M2 proton channel of Influenza A, closed state, S31N, with drug	2ly0	Influenza virus	Viral	4	4	34.0 ± 1.6	0 ± 0	-67.5
1.2.23.01.	M2 proton channel of Influenza A, complex with amantadine	2kqt	Influenza virus	Viral	4	4	30.2 ± 1.3	0 ± 4	-59.6
1.2.24.01.	Protein Vpu, cytoplasmic domain, in DPC micelles	2k7y	Human immunodeficiency virus type 1	Eukaryo. plasma	1	0	4.5 ± 1.4	54 ± 17	-5.4
1.2.24.01.	Protein Vpu, transmembrane helix	1pi7	Human immunodeficiency virus type 1	Eukaryo. plasma	1	1	28.2 ± 5.4	38 ± 4	-23.8
1.2.24.01.	Protein Vpu, cytoplasmic domain, structure in aqueous solution	1vpu	Human immunodeficiency virus type 1	Eukaryo. plasma	1	0	7.4 ± 2.1	64 ± 5	-5.6
1.2.25.01.	Phospholamban	1zll	Homo sapiens	Endoplasm. reticulum	5	5	30.5 ± 1.4	0 ± 2	-76.0
1.2.25.01.	Phosholamban	1fjk	Sus scrofa	Endoplasm. reticulum	1	1	30.1 ± 3.2	38 ± 6	-28.3
1.2.25.01.	Phospholamban	1n7l	Oryctolagus cuniculus	Endoplasm. reticulum	1	1	29.8 ± 3.6	34 ± 12	-32.3
1.2.25.01.	Sarcolipin	1jdm	Homo sapiens	Endoplasm. reticulum	1	1	29.6 ± 2.4	3 ± 7	-28.5
1.2.25.01.	Phospholamban, cytoplasmic helix	1plp	Homo sapiens	Endoplasm. reticulum	1	0	4.0 ± 1.3	80 ± 4	-7.2
1.2.25.01.	Phospholamban, monomer	2kb7	Homo sapiens	Endoplasm. reticulum	1	1	32.0 ± 2.2	15 ± 2	-34.6
1.2.25.02.	Na,K-ATPase regulatory protein FXYD1 (phospholemman)	2jp3	Rattus norvegicus	Endoplasm. reticulum	1	1	31.8 ± 3.2	18 ± 7	-20.2
1.2.25.02.	Na,K-ATPase regulatory protein FXYD1 (phospholemman)	2jo1	Homo sapiens	Endoplasm. reticulum	1	1	30.6 ± 2.5	11 ± 4	-27.8
1.2.26.01.	Outer membrane lipoprotein Wza	2j58	Escherichia coli	Bact. Gram-neg outer	8	8	31.1 ± 0.8	0 ± 0	-123.8
1.2.26.01.	Outer membrane lipoprotein Wza, water-soluble part	2w8h	Escherichia coli	Bact. Gram-neg outer	8	0	1.6 ± 0.2	1 ± 0	-22.1
1.2.27.01.	Fst toxin	2kv5	Enterococcus faecalis	Secreted	1	1	26.0 ± 2.9	35 ± 8	-18.9
1.2.30.01.	Potassium voltage-gated channel subfamily E member 1	2k21	Homo sapiens	Eukaryo. plasma	1	1	12.1 ± 0.4	54 ± 2	-24.7
1.2.31.01.	Cytochrome c nitrite reductase complex	2j7a	Desulfovibrio vulgaris	Bact. Gram-neg inner	2	2	31.8 ± 3.1	0 ± 2	-42.9
1.2.32.01.	Cytochrome P450 2A13	2p85	Homo sapiens	Endoplasm. reticulum	1	0	4.9 ± 0.4	47 ± 2	-10.0
1.2.32.01.	Sterol 14-alpha-demethylase (CYP51), conformation 3	3ksw	Trypanosoma cruzi	Endoplasm. reticulum	1	0	8.0 ± 6.7	61 ± 6	-9.1
1.2.32.01.	Cytochrome P450 2C8	1pq2	Homo sapiens	Endoplasm. reticulum	1	0	3.8 ± 1.8	65 ± 9	-8.6
1.2.32.01.	Cholesterol 7-alpha-monooxygenase (P450 7A1), different conformation	3sn5	Homo sapiens	Endoplasm. reticulum	1	0	6.0 ± 1.9	73 ± 4	-6.5
1.2.32.01.	Sterol 14-alpha-demethylase (CYP51)	3g1q	Trypanosoma brucei	Endoplasm. reticulum	1	0	8.1 ± 1.5	62 ± 12	-10.8
1.2.32.01.	Cytochrome P450 2B4, open state 3	3r1b	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	5.7 ± 0.0	43 ± 5	-9.8
1.2.32.01.	Cytochrome P450 2B4, closed state 2	2q6n	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	5.5 ± 0.4	55 ± 2	-13.0
1.2.32.01.	Cholesterol side-chain cleavage enzyme (P450 11A1), complex with adrenodoxin	3n9y	Homo sapiens	Mitochon. inner	1	0	4.1 ± 0.6	49 ± 5	-6.2
1.2.32.01.	Cytochrome P450 2C9	1og5	Homo sapiens	Endoplasm. reticulum	1	0	7.6 ± 1.0	79 ± 6	-13.7
1.2.32.01.	Cytochrome P450 2E1	3e6i	Homo sapiens	Endoplasm. reticulum	1	0	8.3 ± 2.0	49 ± 8	-14.2
1.2.32.01.	Sterol 14-alpha-demethylase (CYP51), conformation 1	2wuz	Trypanosoma cruzi	Endoplasm. reticulum	1	0	4.0 ± 1.1	75 ± 11	-9.9
1.2.32.01.	Steroid 17-alpha-hydroxylase/17,20 lyase (P450 17A1)	3swz	Homo sapiens	Endoplasm. reticulum	1	0	4.2 ± 1.6	56 ± 3	-8.4
1.2.32.01.	Steroid 21-hydroxylase (P450 C21)	3qz1	Bos taurus	Endoplasm. reticulum	1	0	5.9 ± 1.6	72 ± 3	-10.4
1.2.32.01.	Cytochrome P450 2D6, conformation 2	3tda	Homo sapiens	Endoplasm. reticulum	1	0	8.0 ± 0.7	35 ± 7	-12.5
1.2.32.01.	Cytochrome P450 2B4, closed state 3	3g5n	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	5.7 ± 1.8	65 ± 3	-12.1
1.2.32.01.	Cholesterol side-chain cleavage enzyme (P450 11A1)	3mzs	Bos taurus	Mitochon. inner	1	0	3.2 ± 0.3	33 ± 1	-6.7
1.2.32.01.	Cytochrome P450 3A4, conformation 1	1tqn	Homo sapiens	Endoplasm. reticulum	1	0	8.7 ± 1.0	67 ± 11	-18.5
1.2.32.01.	Cytochrome P450 2R1	3czh	Homo sapiens	Endoplasm. reticulum	1	0	8.3 ± 1.5	48 ± 13	-13.2
1.2.32.01.	Sterol 14-alpha-demethylase (CYP51)	3l4d	Leishmania infantum	Endoplasm. reticulum	1	0	8.4 ± 1.8	66 ± 9	-12.6
1.2.32.01.	Plant cytochrome P450 74A (allene oxide synthase)	3dan	Parthenium argentatum	Vacuole	1	0	7.5 ± 0.4	64 ± 2	-24.1
1.2.32.01.	Cytochrome P450 2B6, different conformation	3ua5	Homo sapiens	Endoplasm. reticulum	1	0	4.7 ± 1.1	55 ± 3	-12.9
1.2.32.01.	Cytochrome P450 11B2, mitochondrial	4dvq	Homo sapiens	Mitochon. inner	1	0	4.8 ± 0.6	48 ± 4	-9.1
1.2.32.01.	Cytochrome P450 2A6	1z10	Homo sapiens	Endoplasm. reticulum	1	0	5.0 ± 1.7	44 ± 18	-9.5
1.2.32.01.	Cytochrome P450 2D6, conformation 1	2f9q	Homo sapiens	Endoplasm. reticulum	1	0	7.0 ± 1.8	29 ± 10	-12.0
1.2.32.01.	Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 1	2q9f	Homo sapiens	Endoplasm. reticulum	1	0	2.8 ± 1.0	86 ± 7	-5.8
1.2.32.01.	Cytochrome P450 120a1	2ve4	Synechocystis sp.	Thylakoid	1	0	6.3 ± 0.9	47 ± 8	-8.6
1.2.32.01.	Cytochrome P450 24a1 (1,25-dihydroxyvitamin D(3) 24-hydroxylase)	3k9v	Rattus norvegicus	Mitochon. inner	1	0	6.6 ± 1.0	49 ± 6	-9.6
1.2.32.01.	Cytochrome P450 2B4, open state 2	1po5	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	3.5 ± 1.4	79 ± 9	-7.2
1.2.32.01.	Cytochrome P450 2B4, open state 1	2bdm	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	10.6 ± 1.0	48 ± 15	-16.2
1.2.32.01.	Cytochrome P450 2B6	3ibd	Homo sapiens	Endoplasm. reticulum	1	0	4.7 ± 1.0	57 ± 3	-10.8
1.2.32.01.	Fatty-acid peroxygenase	1izo	Bacillus subtilis	Bact. Gram-pos plas.	1	0	1.2 ± 0.3	76 ± 1	-5.5
1.2.32.01.	Sterol 14-alpha-demethylase (CYP51), conformation 2	2wx2	Trypanosoma cruzi	Endoplasm. reticulum	1	0	5.9 ± 5.9	63 ± 2	-6.2
1.2.32.01.	Cytochrome P450 2C9, different conformation	1r9o	Homo sapiens	Endoplasm. reticulum	1	0	4.0 ± 1.1	59 ± 8	-10.1
1.2.32.01.	Cytochrome P450 19A1 (aromatase, estrogen synthetase)	3eqm	Homo sapiens	Endoplasm. reticulum	1	0	6.1 ± 1.2	58 ± 8	-12.4
1.2.32.01.	Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 2	3mdm	Homo sapiens	Endoplasm. reticulum	1	0	3.8 ± 1.3	51 ± 8	-5.9
1.2.32.01.	Cholesterol 7-alpha-monooxygenase (P450 7A1)	3dax	Homo sapiens	Endoplasm. reticulum	1	0	1.8 ± 1.9	69 ± 8	-3.9
1.2.32.01.	Cytochrome P450 2D6, conformation 3	3qm4	Homo sapiens	Endoplasm. reticulum	1	0	9.0 ± 1.4	35 ± 11	-9.3
1.2.32.01.	Cytochrome P450	1n97	Thermus thermophilus	Bact. Gram-neg inner	1	0	5.2 ± 0.3	43 ± 5	-9.9
1.2.32.01.	Cytochrome P450 2C5	1nr6	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	10.6 ± 1.0	54 ± 18	-9.1
1.2.32.01.	Cytochrome P450 2C5, different conformation	1dt6	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	7.3 ± 1.0	13 ± 7	-8.8
1.2.32.01.	Cytochrome P450 1A2	2hi4	Homo sapiens	Endoplasm. reticulum	1	0	6.9 ± 1.0	66 ± 9	-16.2
1.2.32.01.	Sterol 14-alpha-demethylase (CYP51)	3ld6	Homo sapiens	Endoplasm. reticulum	1	0	8.9 ± 0.6	57 ± 2	-16.8
1.2.32.01.	Cytochrome P450 3A4, conformation 2	3nxu	Homo sapiens	Endoplasm. reticulum	1	0	9.3 ± 1.0	52 ± 12	-17.5
1.2.32.01.	Cytochrome P450 1B1	3pm0	Homo sapiens	Endoplasm. reticulum	1	0	3.8 ± 0.7	79 ± 1	-7.0
1.2.32.01.	Cytochrome P450 1A1	4i8v	Homo sapiens	Endoplasm. reticulum	1	0	7.1 ± 1.0	64 ± 3	-15.1
1.2.32.01.	Cytochrome P450 120a1, different conformation	2ve3	Synechocystis sp.	Thylakoid	1	0	5.2 ± 1.5	52 ± 15	-6.8
1.2.32.01.	Plant cytochrome P450 74A (allene oxide synthase)	3dsk	Arabidopsis thaliana	Thylakoid	1	0	5.7 ± 0.5	67 ± 3	-20.0
1.2.32.01.	Cytochrome P450 2B4, closed state 1	1suo	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	4.6 ± 1.3	57 ± 4	-14.2
1.2.32.01.	Prostacyclin synthase (cytochrome P450 8A1)	3b6h	Homo sapiens	Endoplasm. reticulum	1	0	5.0 ± 1.6	64 ± 18	-6.3
1.2.33.02.	Alpha-glycerophosphate oxidase (GlpO)	2rgh	Streptomyces sp.	Bact. Gram-pos plas.	1	0	3.9 ± 1.4	71 ± 12	-6.2
1.2.33.02.	Protoporphyrinogen oxidase	2ivd	Myxococcus xanthus	Bact. Gram-neg inner	1	0	3.7 ± 0.2	29 ± 2	-8.0
1.2.33.02.	Monoamine oxidase A	2z5x	Homo sapiens	Mitochon. outer	1	1	31.0 ± 2.1	17 ± 1	-21.4
1.2.33.02.	Protoporphyrinogen oxidase	1sez	Nicotiana tabacum	Mitochon. inner	1	0	2.2 ± 1.0	50 ± 3	-7.0
1.2.33.02.	Protoporphyrinogen oxidase	3nks	Homo sapiens	Mitochon. inner	1	0	4.8 ± 1.0	59 ± 3	-9.6
1.2.33.02.	Monoamine oxidase B, monomer	1s3e	Homo sapiens	Mitochon. outer	2	0	7.3 ± 0.6	37 ± 1	-14.2
1.2.33.02.	Monoamine oxidase A	1o5w	Rattus norvegicus	Mitochon. outer	2	2	31.4 ± 3.4	20 ± 3	-23.1
1.2.33.02.	Monoamine oxidase B, dimer	2xfn	Homo sapiens	Mitochon. outer	2	2	30.0 ± 3.2	14 ± 0	-14.5
1.2.34.01.	Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4)	2lat	Homo sapiens	Endoplasm. reticulum	1	1	31.8 ± 3.5	23 ± 16	-21.3
1.2.34.01.	Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4)	1rkl	Saccharomyces cerevisiae	Endoplasm. reticulum	1	1	24.8 ± 3.2	22 ± 8	-18.4
1.2.36.01.	Hemagglutinin-neuraminidase glycoprotein	1v3e	Human parainfluenza virus 3	Eukaryo. plasma	2	0	1.9 ± 0.4	81 ± 34	-6.5
1.2.37.01.	ADP-ribosyl cyclase 1	3f6y	Homo sapiens	Eukaryo. plasma	1	0	2.5 ± 2.4	51 ± 9	-6.3
1.2.38.01.	Penicillin-binding protein 1B	3vma	Escherichia coli	Bact. Gram-neg inner	1	1	29.8 ± 2.0	25 ± 3	-21.6
1.2.38.01.	Penicillin-binding protein 2	2olv	Staphylococcus aureus	Bact. Gram-pos plas.	1	0	3.7 ± 2.0	58 ± 8	-7.3
1.2.38.01.	Glycosyltransferase MtgA	3hzs	Staphylococcus aureus	Bact. Gram-pos plas.	1	0	7.0 ± 1.1	54 ± 9	-14.6
1.2.38.01.	Penicillin-binding protein 1A	2oqo	Aquifex aeolicus	Bact. Gram-neg inner	1	0	3.0 ± 1.0	40 ± 6	-11.0
1.2.38.01.	Monofunctional glycosyltransferase	3vmr	Staphylococcus aureus	Bact. Gram-pos plas.	1	1	30.8 ± 1.2	25 ± 2	-35.4
1.2.38.02.	Lysozyme	3hde	Enterobacteria phage p21	Secreted	1	0	1.8 ± 1.4	55 ± 10	-4.7
1.2.38.03.	Endo-type membrane-bound lytic murein transglycosylase A	2y8p	Escherichia coli	Bact. Gram-neg outer	1	0	0.0 ± 3.6	86 ± 15	-2.2
1.2.39.01.	Endoplasmic reticulum aminopeptidase 2	3se6	Homo sapiens	Endoplasm. reticulum	1	0	2.5 ± 1.8	60 ± 21	-4.5
1.2.39.01.	Endoplasmic reticulum aminopeptidase 1, different conformation	2yd0	Homo sapiens	Endoplasm. reticulum	1	0	4.1 ± 2.2	59 ± 8	-4.6
1.2.39.01.	Endoplasmic reticulum aminopeptidase 1	3mdj	Homo sapiens	Endoplasm. reticulum	1	0	1.9 ± 3.6	63 ± 10	-4.6
1.2.39.02.	Stromelysin-1	1c3i	Homo sapiens	Eukaryo. plasma	1	0	3.6 ± 1.7	85 ± 17	-4.4
1.2.39.03.	Disintegrin and metalloproteinase domain-containing protein 10	2ao7	Bos taurus	Golgi	1	0	3.1 ± 1.4	81 ± 6	-5.7
1.2.40.01.	Mitochondria fission protein Fis1	1nzn	Homo sapiens	Mitochon. outer	1	0	6.1 ± 1.4	72 ± 8	-9.3
1.2.41.01.	Acyl-CoA-binding protein	2cb8	Homo sapiens	Peroxisome	1	0	2.7 ± 2.0	74 ± 29	-5.2
1.2.41.01.	Acyl-CoA-binding domain-containing protein 4	2wh5	Homo sapiens	Peroxisome	1	0	7.2 ± 2.4	77 ± 26	-5.7
1.2.41.01.	Acyl-CoA-binding domain-containing protein 5	3flv	Homo sapiens	Peroxisome	1	0	4.6 ± 2.8	28 ± 3	-4.9
1.2.42.01.	Glideosome-associated protein 50	3tgh	Plasmodium falciparum	Endoplasm. reticulum	1	0	4.2 ± 3.4	69 ± 3	-4.3
1.2.43.01.	E1/E2 envelope glycoprotein complex	2yew	Barmah forest virus	Viral	8	8	30.0 ± 0.8	0 ± 0	-53.5
1.2.43.01.	Envelope glycoprotein	1urz	Tick-borne encephalitis virus	Viral	3	0	5.9 ± 0.9	1 ± 8	-10.3
1.2.43.01.	Envelope protein	3g7t	Dengue virus	Viral	3	0	5.9 ± 0.9	1 ± 3	-12.2
1.2.43.01.	E1/E2 envelope glycoprotein complex	3j2w	Chikungunya virus	Viral	8	8	30.8 ± 0.9	2 ± 0	-134.1
1.2.43.01.	Capsid envelop protein complex	3j2p	Dengue virus	Viral	4	8	22.8 ± 0.4	0 ± 0	-62.7
1.2.43.01.	Major envelope glycoprotein E, ectodomain	1ok8	Dengue virus	Viral	3	0	5.2 ± 0.9	0 ± 6	-9.5
1.2.43.02.	Fusion glycoprotein E1	1rer	Semiliki forest virus	Viral	3	0	2.6 ± 2.0	38 ± 5	-6.5
1.2.43.03.	Envelope glycoprotein B	3nw8	Human herpesvirus	Viral	3	0	4.6 ± 0.0	1 ± 1	-11.7
1.2.43.04.	Glycoprotein G	2cmz	Vesicular stomatitis virus	Viral	3	0	6.6 ± 0.0	3 ± 0	-10.5
1.2.43.05.	Major envelope glycoprotein	3duz	Autographa californica nuclear polyhedrosis virus	Viral	3	0	3.2 ± 0.4	4 ± 6	-9.3
1.2.43.06.	Spike glycoprotein	2ghv	Human SARS coronavirus	Viral	1	0	3.8 ± 1.9	45 ± 9	-6.8
1.2.44.01.	Amyloid beta A4 protein (peptide 671-770)	2lp1	Homo sapiens	Eukaryo. plasma	1	1	23.6 ± 5.6	38 ± 5	-21.2
1.2.44.01.	Amyloid beta A4 protein (peptide 672-711)	1ba4	Homo sapiens	Eukaryo. plasma	1	0	6.0 ± 0.3	85 ± 5	-10.9
1.2.44.01.	Amyloid beta A4 protein, peptide 686-726, dimer	2loh	Homo sapiens	Eukaryo. plasma	2	2	32.8 ± 1.6	1 ± 1	-34.1
1.2.44.01.	Amyloid beta A4 protein, peptide 686-726	2llm	Homo sapiens	Eukaryo. plasma	1	1	32.8 ± 2.2	30 ± 0	-30.8
1.3.01.01.	Outer membrane protein A from Klebsiella	2k0l	Klebsiella pneumoniae	Bact. Gram-neg outer	1	8	24.3 ± 2.3	18 ± 6	-26.8
1.3.01.01.	Transmembrane beta-barrel platform protein	2jmm	Designed proteins	Undefined	1	8	23.9 ± 1.3	4 ± 4	-32.3
1.3.01.01.	Outer membrane protein A (OMPA), disordered loops	1qjp	Escherichia coli	Bact. Gram-neg outer	1	8	25.4 ± 1.5	11 ± 1	-29.5
1.3.01.01.	Outer membrane protein A (OMPA)	1bxw	Escherichia coli	Bact. Gram-neg outer	1	8	25.4 ± 1.9	5 ± 1	-35.6
1.3.01.02.	Attachment invasion locus protein	3qra	Yersinia pestis	Bact. Gram-neg outer	1	8	25.2 ± 1.4	14 ± 7	-32.2
1.3.01.02.	Attachment invasion locus protein, complex with the heparin analogue	3qrc	Yersinia pestis	Bact. Gram-neg outer	1	8	24.6 ± 1.2	7 ± 5	-31.6
1.3.01.02.	Outer membrane protein X (OMPX)	1qj8	Escherichia coli	Bact. Gram-neg outer	1	8	23.6 ± 2.8	12 ± 5	-30.7
1.3.02.01.	Outer membrane protein H (OprH)	2lhf	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	8	20.6 ± 0.6	15 ± 3	-16.4
1.3.02.01.	Outer membrane protein NspA	1p4t	Neisseria meningitidis	Bact. Gram-neg outer	1	8	24.9 ± 2.4	22 ± 3	-42.9
1.3.03.01.	Outer membrane protein W	2f1v	Escherichia coli	Bact. Gram-neg outer	1	8	25.4 ± 1.4	10 ± 3	-38.3
1.3.03.01.	Outer membrane protein OprG	2x27	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	8	23.9 ± 1.7	7 ± 3	-39.6
1.3.04.03.	Lipid A acylase PagP	3gp6	Escherichia coli	Bact. Gram-neg outer	1	8	24.7 ± 1.5	40 ± 1	-32.5
1.3.04.03.	Lipid A acylase PagP, different conformation of loops	1thq	Escherichia coli	Bact. Gram-neg outer	1	8	23.4 ± 2.5	27 ± 3	-31.3
1.3.05.01.	Lipid A deacylase PagL	2erv	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	8	24.7 ± 1.8	20 ± 2	-41.1
1.3.06.01.	Major outer membrane protein from Thermus thermophilus	3dzm	Thermus thermophilus	Bact. Gram-neg outer	1	8	28.5 ± 2.6	6 ± 10	-50.3
1.3.07.01.	Plasminogen activator PLA (coagulase/fibrinolysin)	2x55	Yersinia pestis	Bact. Gram-neg outer	1	10	25.6 ± 1.9	4 ± 5	-43.9
1.3.07.01.	Outer membrane protease OmpT	1i78	Escherichia coli	Bact. Gram-neg outer	1	10	26.5 ± 1.6	5 ± 6	-46.9
1.3.07.01.	Plasminogen activator PLA (coagulase/fibrinolysin), disordered loop	2x4m	Yersinia pestis	Bact. Gram-neg outer	10	10	24.2 ± 1.6	2 ± 2	-46.1
1.3.08.01.	Outer membrane adhesin/invasin OpcA, disordered loops	2vdf	Neisseria meningitidis	Bact. Gram-neg outer	1	10	24.8 ± 1.2	8 ± 0	-47.0
1.3.08.01.	Outer membrane adhesin/invasin OpcA	1k24	Neisseria meningitidis	Bact. Gram-neg outer	1	10	25.4 ± 1.3	10 ± 11	-41.7
1.3.09.01.	Lipid A deacylase LpxR	3fid	Salmonella enterica	Bact. Gram-neg outer	1	12	25.6 ± 2.0	24 ± 0	-58.6
1.3.10.01.	Acidic sugar-specific porin NanC	2wjr	Escherichia coli	Bact. Gram-neg outer	1	12	23.3 ± 1.5	4 ± 4	-47.5
1.3.11.01.	Serine protease EspP, post-cleavage structure	2qom	Escherichia coli	Bact. Gram-neg outer	1	12	25.1 ± 1.6	6 ± 7	-55.9
1.3.11.01.	Esterase EstA	3kvn	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	12	24.4 ± 1.5	4 ± 2	-48.7
1.3.11.01.	Hemoglobin-binding protease Hbp autotransporter	3aeh	Escherichia coli	Bact. Gram-neg outer	1	12	25.2 ± 1.1	4 ± 0	-41.9
1.3.11.01.	Autotransporter BrkA	3qq2	Bordetella pertussis	Bact. Gram-neg outer	1	12	24.6 ± 1.5	4 ± 1	-44.1
1.3.11.01.	Serine protease EspP, pre-cleavage structure	3slj	Escherichia coli	Bact. Gram-neg outer	1	12	25.4 ± 1.2	6 ± 1	-53.1
1.3.11.01.	Autotransporter NalP	1uyn	Neisseria meningitidis	Bact. Gram-neg outer	1	12	25.3 ± 1.3	8 ± 8	-47.6
1.3.11.01.	Autotransporter NalP, different conformation	1uyo	Neisseria meningitidis	Bact. Gram-neg outer	1	12	23.6 ± 1.4	8 ± 0	-42.7
1.3.11.02.	Intimin	4e1s	Escherichia coli	Bact. Gram-neg outer	1	12	24.4 ± 1.6	9 ± 2	-45.2
1.3.11.02.	Invasin	4e1t	Yersinia pseudotuberculosis	Bact. Gram-neg outer	1	12	25.6 ± 1.4	9 ± 1	-51.0
1.3.12.01.	Outer membrane phospholipase A	1qd6	Escherichia coli	Bact. Gram-neg outer	2	12	23.9 ± 1.0	0 ± 0	-77.2
1.3.12.01.	Outer membrane phospholipase A, monomer	1qd5	Escherichia coli	Bact. Gram-neg outer	1	12	24.6 ± 1.2	6 ± 0	-52.6
1.3.13.01.	Bacterial Nucleoside Transporter Ts	1tly	Escherichia coli	Bact. Gram-neg outer	1	12	23.4 ± 1.5	8 ± 0	-48.1
1.3.14.01.	Fatty Acid Transporter FadL, D348R, open channel	3pgr	Escherichia coli	Bact. Gram-neg outer	1	14	25.4 ± 1.4	3 ± 1	-50.8
1.3.14.01.	Fatty Acid Transporter FadL, F3E, open channel	3pgu	Escherichia coli	Bact. Gram-neg outer	1	14	25.2 ± 1.5	1 ± 1	-51.5
1.3.14.01.	Toluene transporter TbuX	3bry	Ralstonia pickettii	Bact. Gram-neg outer	1	14	25.4 ± 1.5	1 ± 2	-57.7
1.3.14.01.	Fatty Acid Transporter FadL, delS3, open channel	2r88	Escherichia coli	Bact. Gram-neg outer	1	14	24.0 ± 1.4	6 ± 2	-53.8
1.3.14.01.	Fatty Acid Transporter FadL	1t16	Escherichia coli	Bact. Gram-neg outer	1	14	25.4 ± 1.3	6 ± 7	-58.0
1.3.14.01.	Toluene transporter TodX	3bs0	Pseudomonas putida	Bact. Gram-neg outer	1	14	23.4 ± 1.4	7 ± 7	-61.3
1.3.14.01.	FadL homologue	3dwo	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	14	24.8 ± 1.6	6 ± 3	-54.7
1.3.15.01.	Outer membrane protein G (OMPG), open state 2	2x9k	Escherichia coli	Bact. Gram-neg outer	1	14	24.7 ± 1.2	5 ± 2	-62.7
1.3.15.01.	Outer membrane protein G (OMPG), open state 1	2iwv	Escherichia coli	Bact. Gram-neg outer	1	14	25.3 ± 1.4	3 ± 5	-61.3
1.3.15.01.	Outer membrane protein G (OMPG), closed state	2iww	Escherichia coli	Bact. Gram-neg outer	1	14	24.7 ± 1.4	6 ± 4	-63.3
1.3.16.01.	Porin OmpF	3nsg	Salmonella enterica	Bact. Gram-neg outer	3	48	23.6 ± 0.8	0 ± 0	-123.4
1.3.16.01.	Porin B (PorB)	3a2s	Neisseria meningitidis	Bact. Gram-neg outer	3	48	24.4 ± 1.0	0 ± 0	-102.1
1.3.16.01.	Porin B (PorB)	4aui	Neisseria gonorrhoeae	Bact. Gram-neg outer	3	48	24.2 ± 0.8	0 ± 0	-89.7
1.3.16.01.	Porin OmpF	3pox	Escherichia coli	Bact. Gram-neg outer	3	48	24.0 ± 0.8	0 ± 0	-136.2
1.3.16.01.	Osmoporin OMPC, isoform 1	2ixx	Escherichia coli	Bact. Gram-neg outer	3	48	26.2 ± 1.3	0 ± 1	-142.5
1.3.16.01.	Porin	1osm	Klebsiella pneumoniae	Bact. Gram-neg outer	3	48	24.0 ± 1.1	0 ± 0	-136.6
1.3.16.01.	Osmoporin OMPC, isoform 2	2ixw	Escherichia coli	Bact. Gram-neg outer	3	48	24.5 ± 1.0	0 ± 0	-121.0
1.3.16.01.	Anion-selective porin	2fgq	Comamonas acidovorans	Bact. Gram-neg outer	3	48	25.0 ± 0.9	0 ± 0	-130.8
1.3.16.01.	Osmoporin OMPC	2j1n	Escherichia coli	Bact. Gram-neg outer	3	48	25.1 ± 1.2	0 ± 2	-126.2
1.3.16.01.	Osmoporin OMPC	3upg	Salmonella typhimurium	Bact. Gram-neg outer	3	48	23.4 ± 0.7	0 ± 0	-118.0
1.3.16.01.	Phosphoporin (PhoE)	1pho	Escherichia coli	Bact. Gram-neg outer	3	48	24.1 ± 1.2	0 ± 0	-134.1
1.3.16.02.	Porin	2por	Rhodobacter capsulatus	Bact. Gram-neg outer	3	48	23.4 ± 0.6	0 ± 0	-114.8
1.3.16.02.	Porin	3prn	Rhodopseudomonas blastica	Bact. Gram-neg outer	3	48	23.2 ± 0.5	0 ± 0	-127.6
1.3.16.03.	Porin OprP	2o4v	Pseudomonas aeruginosa	Bact. Gram-neg outer	3	48	23.9 ± 1.1	0 ± 0	-129.6
1.3.16.04.	Porin B	4gey	Pseudomonas putida	Bact. Gram-neg outer	16	1	24.2 ± 1.6	6 ± 2	-61.3
1.3.16.04.	Porin B, low pH structure	4gf4	Pseudomonas putida	Bact. Gram-neg outer	1	16	22.4 ± 1.1	5 ± 2	-54.3
1.3.17.01.	Filamentous hemagglutinin transporter FhaC	2qdz	Bordetella pertussis	Bact. Gram-neg outer	1	16	24.4 ± 1.1	7 ± 7	-69.1
1.3.17.01.	Filamentous hemagglutinin transporter FhaC, R450A, disordered loops	3njt	Bordetella pertussis	Bact. Gram-neg outer	1	16	23.6 ± 0.9	7 ± 0	-65.8
1.3.18.01.	Maltoporin	1af6	Escherichia coli	Bact. Gram-neg outer	3	54	25.1 ± 0.7	0 ± 0	-117.9
1.3.18.01.	Maltoporin	2mpr	Salmonella enterica	Bact. Gram-neg outer	3	54	24.5 ± 1.0	0 ± 0	-109.7
1.3.18.01.	Sucrose-specific porin	1a0s	Salmonella enterica	Bact. Gram-neg outer	3	54	23.8 ± 1.1	0 ± 0	-103.5
1.3.19.01.	Histidine porin OpdC	3sy9	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.4 ± 0.8	5 ± 0	-63.2
1.3.19.01.	Glycine-glutamate dipeptide porin OpdP	3syb	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.6 ± 0.9	8 ± 0	-62.0
1.3.19.01.	Protein OpdK	2qtk	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.3 ± 1.0	3 ± 0	-62.4
1.3.19.01.	Outer membrane porin OpdL	2y0h	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.0 ± 1.0	3 ± 0	-55.7
1.3.19.01.	Porin OpdF	3szd	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	22.0 ± 1.6	3 ± 0	-60.3
1.3.19.01.	Pyroglutamate porin OpdO	2y0k	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.8 ± 1.2	1 ± 0	-55.8
1.3.19.01.	Porin OpdQ	3t24	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.0 ± 1.3	2 ± 0	-56.5
1.3.19.01.	Cis-aconitate porin OpdH	2y0l	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	21.4 ± 1.5	6 ± 1	-57.2
1.3.19.01.	Outer membrane porin OprD	2odj	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.0 ± 0.8	8 ± 0	-63.1
1.3.19.01.	BenF-like porin	3jty	Pseudomonas fluorescens	Bact. Gram-neg outer	1	18	24.2 ± 1.2	1 ± 0	-59.8
1.3.19.01.	Outer membrane porin OprD, different conformation of loops	3sy7	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.8 ± 1.1	4 ± 2	-63.5
1.3.19.02.	Alginate export protein, AlgE, different conformation of loops	4afk	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	24.8 ± 0.9	3 ± 0	-73.0
1.3.19.02.	Alginate export protein, AlgE	3rbh	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.4 ± 1.2	4 ± 0	-72.0
1.3.20.01.	Outer membrane cobalamin transporter BtuB, complex with colicin E2 R-domain	2ysu	Escherichia coli	Bact. Gram-neg outer	1	22	24.2 ± 1.0	5 ± 0	-75.2
1.3.20.01.	Outer membrane cobalamin transporter BtuB, with cyanocobalamin	3m8d	Escherichia coli	Bact. Gram-neg outer	1	22	23.3 ± 0.8	6 ± 1	-70.5
1.3.20.01.	Fe-regulated protein B	4aip	Neisseria meningitidis	Bact. Gram-neg outer	3	66	23.4 ± 0.3	0 ± 0	-144.6
1.3.20.01.	Outer membrane cobalamin transporter BtuB, meso form	2guf	Escherichia coli	Bact. Gram-neg outer	1	22	23.4 ± 0.9	6 ± 7	-69.3
1.3.20.01.	Outer membrane cobalamin transporter BtuB, complex with colicin E3 R-domain	1ujw	Escherichia coli	Bact. Gram-neg outer	1	22	23.6 ± 1.1	5 ± 0	-71.5
1.3.20.01.	Fe-regulated protein B, different variant	4aiq	Neisseria meningitidis	Bact. Gram-neg outer	1	22	23.6 ± 0.9	6 ± 0	-69.7
1.3.20.01.	Colicin I receptor complex with binding domain of Colicin Ia	2hdi	Escherichia coli	Bact. Gram-neg outer	1	22	23.4 ± 0.9	3 ± 3	-72.7
1.3.20.01.	Hemophore receptor HasR	3csl	Serratia marcescens	Bact. Gram-neg outer	1	22	25.4 ± 1.3	4 ± 5	-72.2
1.3.20.01.	Pesticin receptor FyuA	4epa	Yersinia pestis	Bact. Gram-neg outer	1	22	23.6 ± 0.8	3 ± 0	-73.5
1.3.20.01.	Ferric hydroxamate uptake receptor FhuA, complex with TonB	2grx	Escherichia coli	Bact. Gram-neg outer	1	22	24.6 ± 1.1	3 ± 0	-77.2
1.3.20.01.	Colicin I receptor	2hdf	Escherichia coli	Bact. Gram-neg outer	1	22	23.4 ± 0.9	4 ± 0	-70.9
1.3.20.01.	Enantio-pyochelin receptor FetA	3qlb	Pseudomonas fluorescens	Bact. Gram-neg outer	1	22	23.4 ± 0.8	7 ± 0	-75.3
1.3.20.01.	Ferric hydroxamate uptake receptor FhuA	1qfg	Escherichia coli	Bact. Gram-neg outer	1	22	24.7 ± 1.0	5 ± 1	-81.3
1.3.20.01.	Outer membrane cobalamin transporter BtuB, complex with TonB	2gsk	Escherichia coli	Bact. Gram-neg outer	1	22	23.4 ± 0.7	5 ± 0	-77.5
1.3.20.01.	Outer membrane receptor FauA	3efm	Bordetella pertussis	Bact. Gram-neg outer	1	22	24.7 ± 0.6	11 ± 0	-77.5
1.3.20.01.	Ferric enterobactin receptor FepA	1fep	Escherichia coli	Bact. Gram-neg outer	1	22	24.3 ± 1.1	1 ± 0	-77.2
1.3.20.01.	Outer membrane heme transporter ShuA	3fhh	Shigella dysenteriae	Bact. Gram-neg outer	1	22	24.6 ± 0.9	5 ± 0	-70.7
1.3.20.01.	Outer membrane transporter FecA	1kmo	Escherichia coli	Bact. Gram-neg outer	1	22	24.5 ± 1.2	3 ± 0	-69.6
1.3.20.01.	Transferrin-binding protein A, complex with human serotransferrin	3v89	Neisseria meningitidis	Bact. Gram-neg outer	1	22	22.8 ± 0.8	3 ± 1	-68.9
1.3.20.01.	Outer membrane cobalamin transporter BtuB	1nqe	Escherichia coli	Bact. Gram-neg outer	1	22	23.4 ± 1.0	5 ± 0	-68.8
1.3.20.01.	Fe(III)-pyochelin receptor FptA	1xkw	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	22	24.8 ± 1.0	5 ± 4	-84.3
1.3.20.01.	Outer membrane transporter FecA, different conformation	1kmp	Escherichia coli	Bact. Gram-neg outer	1	22	24.9 ± 0.9	4 ± 0	-74.0
1.3.20.01.	Transferrin-binding protein A, complex with full-length transferrin	3v8x	Neisseria meningitidis	Bact. Gram-neg outer	1	24	23.2 ± 0.6	3 ± 0	-66.6
1.3.20.01.	Pyoverdine Outer Membrane Receptor FpvA	2iah	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	22	24.0 ± 0.5	8 ± 0	-79.7
1.3.21.01.	Outer membrane usher protein FimD, complex with FimC-FimH	3rfz	Escherichia coli	Bact. Gram-neg outer	1	24	23.8 ± 0.8	5 ± 0	-65.1
1.3.21.01.	P pilus usher PapC translocation domain	2vqi	Escherichia coli	Bact. Gram-neg outer	1	24	23.1 ± 1.0	3 ± 0	-61.0
1.3.21.01.	Outer membrane usher protein FimD, complex with FimC-FimF-FimG-FimH	4j3o	Escherichia coli	Bact. Gram-neg outer	1	24	23.8 ± 1.4	1 ± 1	-52.9
1.3.21.01.	Outer membrane usher protein FimD	3ohn	Escherichia coli	Bact. Gram-neg outer	1	24	21.2 ± 1.1	5 ± 0	-45.4
1.3.22.01.	VDAC-1 channel, NMR model	2k4t	Homo sapiens	Mitochon. outer	1	19	22.0 ± 1.5	1 ± 1	-34.8
1.3.22.01.	VDAC-1 channel	2jk4	Homo sapiens	Mitochon. outer	1	19	23.4 ± 2.3	0 ± 1	-40.0
1.3.22.01.	VDAC-1 channel	3emn	Mus musculus	Mitochon. outer	1	19	23.4 ± 1.1	5 ± 1	-52.5
1.3.23.01.	Autotransporter Hia, 992-1098	2gr7	Haemophilus influenzae	Bact. Gram-neg outer	3	12	22.7 ± 2.0	0 ± 1	-43.5
1.3.23.01.	Autotransporter Hia, 937-1098, a different conformation	3emo	Haemophilus influenzae	Bact. Gram-neg outer	3	12	22.8 ± 1.9	4 ± 0	-40.1
1.3.23.01.	Adhesin yadA	2lme	Yersinia enterocolitica	Bact. Gram-neg outer	3	15	23.4 ± 2.2	0 ± 1	-37.7
1.3.24.01.	Outer membrane protein TolC	1ek9	Escherichia coli	Bact. Gram-neg outer	3	12	24.6 ± 1.4	0 ± 2	-56.1
1.3.24.01.	Multidrug Resistance (VceC) protein	1yc9	Vibrio cholerae	Bact. Gram-neg outer	3	12	24.6 ± 1.0	0 ± 0	-62.2
1.3.24.01.	Drug-Discharge Outer Membrane Protein, OprM	1wp1	Pseudomonas aeruginosa	Bact. Gram-neg outer	3	12	24.7 ± 1.2	0 ± 0	-64.0
1.3.24.01.	Cation efflux system protein CusC	3pik	Escherichia coli	Bact. Gram-neg outer	3	12	24.3 ± 1.2	1 ± 0	-33.8
1.3.24.01.	Outer membrane protein TolC, mutant, open conformation 1	2wmz	Escherichia coli	Bact. Gram-neg outer	3	12	24.4 ± 0.8	0 ± 0	-52.8
1.3.24.01.	Outer membrane protein TolC, mutant, open conformation 3	2vdd	Escherichia coli	Bact. Gram-neg outer	3	12	24.4 ± 1.2	0 ± 0	-57.7
1.3.24.01.	Outer membrane protein TolC, mutant, open conformation 4	2xmn	Escherichia coli	Bact. Gram-neg outer	3	12	23.6 ± 1.4	0 ± 0	-50.5
1.3.24.01.	Outer membrane protein TolC, mutant, open conformation 2	2vde	Escherichia coli	Archaebac.	3	12	24.4 ± 1.2	0 ± 0	-57.4
1.3.25.01.	Necrotic enteritis toxin B, NetB	4h56	Clostridium perfringens	Secreted	7	17	25.2 ± 0.8	0 ± 0	-50.7
1.3.25.01.	Gamma-hemolysin, heterodimer of components A and B	2qk7	Staphylococcus aureus	Secreted	2	0	2.9 ± 2.0	83 ± 11	-5.7
1.3.25.01.	Necrotic enteritis toxin B	4i0n	Clostridium perfringens	Secreted	1	0	1.6 ± 2.4	38 ± 7	-4.3
1.3.25.01.	Gamma-hemolysin, component B	3lkf	Staphylococcus aureus	Secreted	1	0	1.7 ± 2.5	51 ± 11	-4.5
1.3.25.01.	Leukocidin F	1pvl	Staphylococcus aureus	Secreted	1	0	4.0 ± 3.2	47 ± 10	-3.7
1.3.25.01.	Alpha-hemolysin	7ahl	Staphylococcus aureus	Secreted	7	14	23.5 ± 0.9	0 ± 1	-49.3
1.3.25.01.	Gamma-hemolysin, complete channel, hetero-octamer	3b07	Staphylococcus aureus	Secreted	8	16	21.4 ± 1.0	0 ± 0	-32.8
1.3.25.02.	Hemolysin	1xez	Vibrio cholerae	Secreted	1	0	8.2 ± 2.3	19 ± 6	-6.0
1.3.25.02.	Cytolysin and hemolysin HlyA Pore-forming toxin	3o44	Vibrio cholerae	Secreted	7	14	24.6 ± 0.0	0 ± 0	-33.1
1.3.26.01.	Porin MspA	1uun	Mycobacterium smegmatis	Bact. Gram-pos cell wall	8	16	40.7 ± 2.1	0 ± 0	-71.0
1.3.27.01.	Capsule assembly protein Wzi	2ynk	Escherichia coli	Bact. Gram-neg outer	1	18	23.8 ± 1.3	6 ± 1	-58.2
2.1.01.01.	Snake phospholipase A2, group II, B	1jia	Agkistrodon halys pallas	Secreted	1	0	3.3 ± 0.5	78 ± 4	-11.2
2.1.01.01.	Phospholipase A2 homolog, taipoxin beta chain	3vbz	Oxyuranus scutellatus scutellatus	Secreted	1	0	2.8 ± 0.7	87 ± 2	-7.7
2.1.01.01.	Snake phospholipase A2, group I, isoform 2	1u4j	Bungarus caeruleus	Secreted	1	0	2.2 ± 0.6	83 ± 4	-8.5
2.1.01.01.	Myotoxin II	1xxs	Bothrops moojeni	Secreted	1	0	4.5 ± 1.2	76 ± 10	-5.3
2.1.01.01.	Phospholipase A2 homolog, ammodytin L	3dih	Vipera ammodytes ammodytes	Secreted	1	0	5.0 ± 0.4	82 ± 5	-14.4
2.1.01.01.	Snake phospholipase A2, acidic, group II	1ijl	Agkistrodon acutus	Secreted	1	0	4.2 ± 1.2	83 ± 12	-7.5
2.1.01.01.	Snake phospholipase A2 natratoxin, group I	2osh	Naja atra	Secreted	1	0	2.6 ± 1.6	83 ± 11	-6.1
2.1.01.01.	Ammodytin L1 isoform	3ux7	Vipera ammodytes meridionalis	Secreted	1	0	2.7 ± 0.3	82 ± 1	-13.2
2.1.01.01.	Snake phospholipase A2, group II, neutral	1bjj	Agkistrodon halys pallas	Secreted	1	0	2.6 ± 0.7	86 ± 5	-8.4
2.1.01.01.	Snake phospholipase A2, group I, KPA2	1g2x	Bungarus caeruleus	Secreted	1	0	3.8 ± 1.5	84 ± 10	-5.4
2.1.01.01.	Snake phospholipase A2, group II, VRV-PL-VIIIa	1zwp	Daboia russelli pulchella	Secreted	1	0	4.9 ± 1.0	76 ± 7	-12.5
2.1.01.01.	Snake phospholipase A2, ammodytoxin A, group II	3g8g	Vipera ammodytes ammodytes	Secreted	1	0	4.1 ± 0.9	80 ± 6	-11.0
2.1.01.01.	Snake phospholipase A2, acidic, group I	2wq5	Naja naja	Secreted	1	0	3.4 ± 0.3	89 ± 6	-6.2
2.1.01.01.	Snake phospholipase A2, group II	1vap	Agkistridon piscivorus	Secreted	1	0	5.1 ± 0.6	88 ± 5	-10.3
2.1.01.01.	Snake phospholipase A2, group I, isoform 1	1tc8	Bungarus caeruleus	Secreted	1	0	3.1 ± 1.4	89 ± 11	-5.0
2.1.01.01.	Phospholipase A2, group IIA	1n28	Homo sapiens	Secreted	1	0	3.6 ± 0.6	88 ± 4	-7.0
2.1.01.01.	Snake phospholipase A2 homolog bothropstoxin-1, group II	3i03	Bothrops jararacussu	Secreted	1	0	2.5 ± 0.5	76 ± 5	-10.6
2.1.01.01.	Snake phospholipase A2, isoform 3	2osn	Bungarus caeruleus	Secreted	1	0	2.4 ± 0.6	84 ± 4	-5.8
2.1.01.01.	Snake phospholipase A2 isoform 5, group I	1y75	Naja sagittifera	Secreted	1	0	4.4 ± 0.7	81 ± 10	-5.7
2.1.01.01.	Snake phospholipase A2, group II (ecarpholin S)	2qhd	Echis carinatus	Secreted	1	0	8.1 ± 0.6	79 ± 5	-12.5
2.1.01.01.	Myotoxin	1s8i	Agkistrodon contortrix laticinctus	Secreted	1	0	4.9 ± 0.7	83 ± 5	-10.6
2.1.01.01.	Myotoxin	1mc2	Agkistrodon acutus	Secreted	1	0	2.4 ± 0.1	80 ± 2	-9.4
2.1.01.01.	Phospholipase A2, group IB	1g4i	Bos taurus	Secreted	1	0	1.9 ± 0.5	87 ± 4	-7.4
2.1.01.01.	Phospholipase A2 BnSP-7	1pa0	Bothrops neuwiedi pauloensis	Secreted	1	0	2.8 ± 1.0	78 ± 10	-6.9
2.1.01.01.	Snake phospholipase A2, group I, isoform 3	3jql	Naja sagittifera	Secreted	1	0	6.2 ± 1.0	85 ± 5	-7.0
2.1.01.01.	Snake phospholipase A2 crotoxin basic chain 2, group II	2qog	Crotalus durissus terrificus	Secreted	1	0	2.1 ± 1.1	84 ± 8	-7.2
2.1.01.01.	Snake phospholipase A2, acidic	2h4c	Daboia russellii siamensis	Secreted	1	0	5.7 ± 1.1	88 ± 10	-9.0
2.1.01.01.	Phospholipase A2	2not	Notechis scutatus scutatus (Mainland tiger snake)	Secreted	1	0	2.6 ± 1.5	73 ± 8	-3.9
2.1.01.01.	Snake phospholipase A2 RV-7, group II	1oqs	Daboia russellii siamensis	Secreted	1	0	2.7 ± 1.1	87 ± 8	-7.9
2.1.01.01.	Snake phospholipase A2, group I	1poa	Naja atra	Secreted	1	0	4.8 ± 1.0	89 ± 7	-10.7
2.1.01.01.	Snake phospholipase A2	2i0u	Vipera nikolskii	Secreted	1	0	5.6 ± 0.9	88 ± 9	-15.2
2.1.01.01.	Snake phospholipase A2, group I	1ae7	Notechis scutatus scutatus	Secreted	1	0	4.7 ± 0.6	84 ± 9	-6.2
2.1.01.01.	Snake phospholipase A2, group II, hypotensive	1umv	Bothrops jararacussu	Secreted	1	0	5.1 ± 0.7	87 ± 4	-8.6
2.1.01.01.	Phospholipase A2, group IB	4p2p	Sus scrofa	Secreted	1	0	3.3 ± 0.8	89 ± 7	-8.6
2.1.01.01.	Phospholipase A2 bothropstoxin-2	2oqd	Bothrops jararacussu	Secreted	1	0	6.0 ± 0.6	85 ± 4	-7.8
2.1.01.01.	Snake phospholipase A2 homolog 1, group II	2ok9	Bothrops pirajai	Secreted	1	0	3.5 ± 1.4	76 ± 7	-7.6
2.1.01.01.	Snake phospholipase A2, ammodytoxin C, group II	3g8h	Vipera ammodytes ammodytes	Secreted	1	0	4.1 ± 1.1	81 ± 8	-9.7
2.1.01.01.	Phospholipase A2, beta bungarotoxin A1 chain, complex with bungarotoxin	1bun	Bungarus multicinctus	Secreted	2	0	1.7 ± 0.9	79 ± 3	-3.8
2.1.01.01.	Snake phospholipase A2, group I	1s6b	Naja sagittifera	Secreted	1	0	3.0 ± 1.1	81 ± 10	-7.5
2.1.01.01.	Snake phospholipase A2, group I, acidic 2	1m8t	Ophiophagus hannah	Secreted	1	0	4.4 ± 0.8	88 ± 6	-6.6
2.1.01.01.	Snake phospholipase A2, group II, RVV-VD	1vip	Vipera russelli	Secreted	1	0	4.4 ± 0.8	85 ± 11	-9.5
2.1.01.01.	Myotoxin	1god	Bothrops godmani	Secreted	1	0	3.0 ± 0.8	80 ± 8	-7.4
2.1.01.01.	Phospholipase A2, group X	1le6	Homo sapiens	Secreted	1	0	7.4 ± 0.9	78 ± 6	-13.2
2.1.01.01.	Phospholipase A2, group IB	3elo	Homo sapiens	Secreted	1	0	0.4 ± 1.5	52 ± 16	-3.5
2.1.01.01.	Myotoxin II	1y4l	Bothrops asper	Secreted	1	0	2.8 ± 0.8	76 ± 7	-10.3
2.1.01.01.	Phospholipase A2 homolog	1ppa	Agkistridon piscivorus	Secreted	1	0	1.2 ± 0.9	85 ± 8	-4.5
2.1.01.01.	Snake phospholipase A2, group I, acidic 1	1gp7	Ophiophagus hannah	Secreted	1	0	4.6 ± 1.0	84 ± 12	-5.8
2.1.01.01.	Snake phospholipase A2, group II	1pp2	Crotalus atrox	Secreted	1	0	3.7 ± 1.3	80 ± 7	-12.9
2.1.01.01.	Snake phospholipase A2, group II	1jlt	Vipera ammodytes meridionalis	Secreted	1	0	2.8 ± 1.0	89 ± 7	-8.7
2.1.01.01.	Snake phospholipase A2-3, group II	1gmz	Bothrops pirajai	Secreted	1	0	3.8 ± 1.5	88 ± 10	-6.7
2.1.01.01.	Snake phospholipase A2 homolog 2, group II	2q2j	Bothrops pirajai	Secreted	1	0	1.9 ± 1.2	89 ± 9	-5.6
2.1.01.01.	Myotoxin II	2aoz	Atropoides nummifer	Secreted	1	0	3.4 ± 0.7	80 ± 3	-11.8
2.1.01.01.	Phospholipase A2 isoform 4	1yxh	Naja sagittifera	Secreted	1	0	1.7 ± 0.5	81 ± 2	-5.2
2.1.01.01.	Snake phospholipase A2, group II, acidic	1bk9	Agkistrodon halys pallas	Secreted	1	0	7.3 ± 0.3	87 ± 3	-11.4
2.1.01.01.	Snake phospholipase A2, group II	1oz6	Echis carinatus	Secreted	1	0	5.6 ± 1.0	84 ± 13	-9.6
2.1.01.01.	Snake phospholipase A2, group I	1ozy	Micropechis ikaheka	Secreted	1	0	2.6 ± 1.0	85 ± 5	-9.0
2.1.01.01.	Snake phospholipase A2, acidic 2, group I	1p7o	Micropechis ikaheka	Secreted	1	0	2.6 ± 0.5	90 ± 2	-9.4
2.1.01.01.	Snake phospholipase A2 homolog zhaoermiatoxin, group II	2ph4	Zhaoermia manqshanensis	Secreted	1	0	4.8 ± 0.8	86 ± 5	-9.2
2.1.01.02.	Phospholipase A2	1poc	Apis mellifera	Secreted	1	0	4.0 ± 1.6	60 ± 6	-9.5
2.1.01.03.	Prokaryotic phospholipase A2	1kp4	Streptomyces violaceoruber	Secreted	1	0	2.4 ± 1.3	42 ± 13	-5.6
2.1.01.04.	Phospholipase A2 homolog	2wg7	Oryza sativa (Rice)	Secreted	1	0	4.0 ± 1.1	77 ± 3	-10.7
2.1.02.01.	Arachidonate 5-lipoxygenase, complex with arachidonic acid	3v99	Homo sapiens	Eukaryo. plasma	1	0	3.0 ± 2.3	88 ± 9	-2.5
2.1.02.01.	Seed lipoxygenase-B	2iuj	Glycine max	Eukaryo. plasma	1	0	1.7 ± 3.0	51 ± 15	-4.8
2.1.02.01.	8R-Lipoxygenase, N-terminal domain	1u5u	Plexaura homomalla	Eukaryo. plasma	1	0	3.1 ± 0.3	72 ± 3	-10.4
2.1.02.01.	Arachidonate 5-lipoxygenase	3o8y	Homo sapiens	Eukaryo. plasma	1	0	2.1 ± 1.0	89 ± 4	-3.8
2.1.02.01.	Arachidonate 15-Lipoxygenase	2p0m	Oryctolagus cuniculus	Eukaryo. plasma	1	0	8.6 ± 0.1	87 ± 5	-14.3
2.1.02.01.	8R-Lipoxygenase, complete structure	3dy5	Plexaura homomalla	Eukaryo. plasma	1	0	2.3 ± 1.5	88 ± 10	-3.2
2.1.02.01.	12S-Lipoxygenase	3d3l	Homo sapiens	Eukaryo. plasma	1	0	5.0 ± 0.6	51 ± 3	-9.0
2.1.02.01.	Seed lipoxygenase-1	1yge	Glycine max	Eukaryo. plasma	1	0	3.0 ± 2.6	68 ± 3	-6.4
2.1.02.01.	8R-Lipoxygenase, central and C-terminal domains	3fg3	Plexaura homomalla	Eukaryo. plasma	1	0	5.0 ± 0.6	86 ± 5	-9.3
2.1.02.01.	Seed lipoxygenase-3	1rrh	Glycine max	Eukaryo. plasma	1	0	3.8 ± 1.3	84 ± 7	-5.6
2.1.02.01.	Seed lipoxygenase-D	2iuk	Glycine max	Eukaryo. plasma	1	0	3.7 ± 1.7	85 ± 8	-6.2
2.1.03.01.	Alpha-toxin	1olp	Clostridium absonum	Secreted	1	0	2.8 ± 1.8	62 ± 11	-6.1
2.1.03.01.	Alpha-toxin (PHLC_CLOP1)	2wxu	Clostridium perfringens	Secreted	1	0	4.0 ± 0.9	85 ± 5	-7.0
2.1.03.01.	Alpha-toxin (PHLC1_CLOPE), open state	1ca1	Clostridium perfringens	Secreted	1	0	2.9 ± 1.0	89 ± 4	-9.3
2.1.03.01.	Alpha-toxin (PHLC_CLOP1) , different conformation	1qmd	Clostridium perfringens	Secreted	1	0	4.8 ± 1.0	80 ± 8	-6.7
2.1.03.01.	Phospholipase C	1p6d	Bacillus cereus	Secreted	1	0	2.8 ± 1.0	52 ± 6	-8.4
2.1.03.01.	Alpha-toxin, different sequence (PHLC2_CLOPE in Uniprot)	1kho	Clostridium perfringens	Secreted	1	0	3.8 ± 1.0	87 ± 4	-8.2
2.1.03.01.	Alpha-toxin (PHLC1_CLOPE), closed state (inactive)	1gyg	Clostridium perfringens	Secreted	1	0	6.1 ± 2.0	75 ± 6	-5.9
2.1.04.01.	Prostaglandin H2 synthase-2 (cyclooxygenase)	1cx2	Mus musculus	Endoplasm. reticulum	2	0	9.7 ± 0.4	89 ± 3	-37.4
2.1.04.01.	Prostaglandin H2 synthase-1	1q4g	Ovis aries	Endoplasm. reticulum	2	0	8.9 ± 0.4	90 ± 1	-43.4
2.1.04.01.	Alpha-dioxygenase 1	4hhr	Arabidopsis thaliana	Endoplasm. reticulum	1	0	10.8 ± 0.1	68 ± 2	-31.4
2.1.05.01.	Squalene-hopene cyclase	2sqc	Alicyclobacillus acidocaldarius	Bact. Gram-pos plas.	2	0	7.4 ± 0.5	90 ± 1	-27.8
2.1.05.01.	Lanosterol synthase	1w6k	Homo sapiens	Endoplasm. reticulum	1	0	7.6 ± 1.0	77 ± 4	-17.8
2.1.05.02.	Farnesyl diphosphate synthase (Geranyltranstransferase)	1rqj	Escherichia coli	Bact. Gram-neg inner	1	0	3.3 ± 0.7	87 ± 3	-7.7
2.1.06.01.	Signal recognition 54 kDa protein	3kl4	Sulfolobus solfataricus	Vacuole	2	0	9.7 ± 0.5	31 ± 5	-16.4
2.1.07.01.	Nonaheme cytochrome c	1duw	Desulfovibrio desulfuricans	Bact. Gram-neg inner	1	0	5.1 ± 0.4	87 ± 10	-4.9
2.1.07.01.	Decaheme cytochrome c MtrF	3pmq	Shewanella oneidensis	Bact. Gram-neg outer	1	0	3.9 ± 0.9	86 ± 2	-6.2
2.1.08.01.	Quinohemoprotein alcohol dehydrogenase ADH IIB	1kv9	Pseudomonas putida	Bact. Gram-neg outer	1	0	1.7 ± 1.1	77 ± 22	-5.9
2.1.08.01.	Cytochrome c peroxidase	1nml	Marinobacter hydrocarbonoclasticus	Bact. Gram-neg inner	1	0	2.2 ± 0.4	83 ± 0	-7.9
2.1.08.01.	Cytochrome c551	451c	Pseudomonas aeruginosa	Bact. Gram-neg inner	1	0	1.4 ± 0.9	85 ± 10	-5.4
2.1.08.01.	Cytochrome c6	1c6s	Thermosynechococcus elongatus	Thylakoid	1	0	0.4 ± 1.7	89 ± 16	-1.3
2.1.08.01.	Cytochrome c6	1f1f	Arthrospira maxima	Thylakoid	1	0	4.8 ± 1.6	80 ± 15	-3.5
2.1.08.01.	Cytochrome c6	1ls9	Cladophora glomerata	Thylakoid	1	0	4.1 ± 1.0	70 ± 14	-2.9
2.1.08.01.	Cytochrome c552	1a8c	Nitrosomonas europaea	Bact. Gram-neg inner	1	0	2.7 ± 1.0	80 ± 11	-4.7
2.1.08.01.	Cytochrome c2	1co6	Rhodopseudomonas viridis	Bact. Gram-neg inner	1	0	1.4 ± 0.7	78 ± 10	-3.3
2.1.08.01.	Mitochondrial cytochrome c	1hrc	Equus caballus	Mitochon. inner	1	0	2.1 ± 1.0	80 ± 16	-2.6
2.1.08.01.	Mono-heme c-type cytochrome ScyA	1kx7	Shewanella putrefaciens	Bact. Gram-neg inner	1	0	1.8 ± 1.1	72 ± 12	-3.2
2.1.08.01.	Cytochrome c2	1cxa	Rhodobacter sphaeroides	Bact. Gram-neg inner	1	0	2.0 ± 1.2	88 ± 13	-4.3
2.1.08.01.	Cytochrome c551	1cor	Pseudomonas stutzeri	Bact. Gram-neg inner	1	0	2.6 ± 1.1	73 ± 12	-6.1
2.1.08.02.	Cytochrome c4	1m70	Pseudomonas stutzeri	Bact. Gram-neg inner	1	0	5.4 ± 0.8	67 ± 14	-5.6
2.1.09.01.	Major allergen I	1puo	Felis catus	Secreted	1	0	3.7 ± 0.8	58 ± 6	-7.8
2.1.10.01.	Glycolipid transfer protein, conformation 2	1swx	Homo sapiens	Eukaryo. plasma	1	0	4.6 ± 1.0	87 ± 8	-7.1
2.1.10.01.	Glycolipid transfer protein, conformation 1	1sx6	Homo sapiens	Eukaryo. plasma	1	0	4.3 ± 1.1	85 ± 5	-10.1
2.1.10.01.	Glycolipid transfer protein, structure 1	1tfj	Bos taurus	Eukaryo. plasma	1	0	3.9 ± 1.0	90 ± 5	-8.3
2.1.10.01.	Glycolipid transfer protein Het-c2	3kv0	Podospora anserina	Eukaryo. plasma	1	0	8.3 ± 1.3	83 ± 5	-13.6
2.1.10.01.	Glycolipid transfer protein, structure 2	1wbe	Bos taurus	Eukaryo. plasma	1	0	1.1 ± 2.4	89 ± 8	-9.4
2.1.11.01.	Spectrin alpha chain	2spc	Drosophila melanogaster	Eukaryo. plasma	2	0	4.3 ± 0.8	87 ± 11	-6.2
2.1.11.01.	Alpha-actinin-2	1hci	Homo sapiens	Eukaryo. plasma	2	0	0.4 ± 0.7	90 ± 12	-5.1
2.1.12.01.	Outer surface protein C	1g5z	Borrelia burgdorferi	Bact. Gram-neg outer	2	0	3.6 ± 0.6	2 ± 8	-7.0
2.1.13.01.	Molt-inhibiting hormone	1j0t	Marsupenaeus japonicus	Secreted	1	0	4.1 ± 0.4	66 ± 6	-7.0
2.1.14.01.	Peroxisomal targeting signal 1 receptor, complex with sterol carrier protein 2	2c0l	Homo sapiens	Peroxisome	2	0	3.1 ± 2.5	85 ± 35	-5.5
2.1.14.01.	Peroxisomal targeting signal 1 receptor	1fch	Homo sapiens	Peroxisome	1	0	6.9 ± 1.2	54 ± 3	-6.7
2.1.14.01.	Peroxisome targeting signal 1 receptor PEX5	1hxi	Trypanosoma brucei	Peroxisome	1	0	3.7 ± 1.0	71 ± 5	-8.1
2.1.14.02.	SusD superfamily protein	3myv	Bacteroides vulgatus	Secreted	1	0	4.0 ± 1.0	64 ± 2	-6.0
2.1.14.03.	Vesicular transport protein sec17	1qqe	Saccharomyces cerevisiae	Vacuole	1	0	5.2 ± 6.1	17 ± 15	-6.2
2.1.15.01.	Epsin-1 (ENTH domain)	1h0a	Rattus norvegicus	Eukaryo. plasma	1	0	3.2 ± 1.1	39 ± 19	-5.3
2.1.15.02.	Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs)	1dvp	Drosophila melanogaster	Endosome	2	0	3.0 ± 0.0	89 ± 0	-6.6
2.1.15.02.	ADP-ribosylation factor-binding protein GGA2	1mhq	Homo sapiens	Golgi	1	0	4.2 ± 1.2	74 ± 5	-4.1
2.1.15.03.	Clathrin assembly lymphoid myeloid leukemia (CALM) protein	1hfa	Rattus norvegicus	Eukaryo. plasma	1	0	14.2 ± 2.0	44 ± 14	-17.9
2.1.16.01.	Myelin basic protein	2lug	Mus musculus	Eukaryo. plasma	1	0	5.6 ± 1.5	79 ± 7	-10.3
2.1.17.01.	Small hydrophilic endoplasmic reticulum-associated protein (Sherp)	2x43	Leishmania major	Endoplasm. reticulum	1	0	4.1 ± 0.3	82 ± 2	-9.0
2.1.18.01.	Annexin XII	1dm5	Hydra vulgaris	Eukaryo. plasma	3	0	2.7 ± 1.0	90 ± 7	-10.2
2.1.18.01.	Annexin IV	2zoc	Homo sapiens	Eukaryo. plasma	1	0	3.4 ± 1.1	82 ± 7	-7.6
2.1.18.01.	Annexin II	1w7b	Homo sapiens	Eukaryo. plasma	1	0	2.4 ± 1.2	87 ± 18	-3.8
2.1.18.01.	Annexin 24	1dk5	Capsicum annuum	Eukaryo. plasma	1	0	3.5 ± 1.3	76 ± 18	-4.4
2.1.18.01.	Annexin VI	1avc	Bos taurus	Eukaryo. plasma	1	0	4.4 ± 1.0	83 ± 1	-8.1
2.1.18.01.	Annexin III	1axn	Homo sapiens	Eukaryo. plasma	1	0	2.7 ± 0.8	77 ± 11	-5.7
2.1.18.01.	Annexin GH1	1n00	Gossypium hirsutum	Eukaryo. plasma	1	0	1.5 ± 2.0	70 ± 17	-3.7
2.1.18.01.	Annexin D1	1ycn	Arabidopsis thaliana	Eukaryo. plasma	1	0	2.3 ± 1.1	78 ± 14	-3.4
2.1.18.01.	Annexin IV	1i4a	Bos taurus	Eukaryo. plasma	3	0	2.5 ± 1.1	89 ± 3	-7.7
2.1.18.01.	Annexin IV	2zhj	Rattus norvegicus	Eukaryo. plasma	1	0	4.1 ± 1.0	80 ± 1	-7.6
2.1.18.01.	Annexin V	1hvf	Homo sapiens	Eukaryo. plasma	1	0	2.3 ± 1.5	79 ± 10	-5.4
2.1.18.01.	Annexin I	1hm6	Sus scrofa	Vesicle	1	0	2.1 ± 0.9	88 ± 7	-5.6
2.1.18.01.	Annexin V	1yii	Gallus gallus	Eukaryo. plasma	1	0	3.1 ± 0.7	79 ± 7	-5.1
2.1.18.01.	Annexin VI	1m9i	Homo sapiens	Eukaryo. plasma	1	0	2.8 ± 0.3	82 ± 0	-8.5
2.1.18.01.	Annexin V	1a8a	Rattus norvegicus	Eukaryo. plasma	3	0	2.1 ± 1.1	89 ± 10	-8.9
2.1.18.01.	Annexin VIII	1w3w	Homo sapiens	Eukaryo. plasma	1	0	4.1 ± 1.0	79 ± 9	-6.2
2.1.18.01.	Annexin IV, monomeric state	1ann	Bos taurus	Eukaryo. plasma	1	0	2.2 ± 1.0	77 ± 3	-6.0
2.1.19.01.	BamCD lipoprotein complex	3tgo	Escherichia coli	Bact. Gram-neg outer	2	0	3.7 ± 2.1	81 ± 20	-3.3
2.1.20.01.	Coagulation factor VIIa	1dan	Homo sapiens	Eukaryo. plasma	4	0	4.2 ± 6.0	25 ± 26	-4.9
2.1.20.01.	Prothrombin	1nl2	Bos taurus	Eukaryo. plasma	1	0	3.9 ± 3.0	18 ± 24	-5.8
2.1.20.01.	Coagulation factor IX	1pfx	Sus scrofa	Eukaryo. plasma	2	0	1.9 ± 6.0	84 ± 10	-3.9
2.1.20.01.	Coagulation factor XIV (protein C) in complex with its receptor	1lqv	Homo sapiens	Eukaryo. plasma	2	0	3.4 ± 3.9	53 ± 14	-5.6
2.1.20.01.	Osteocalcin	1q8h	Sus scrofa	Secreted	1	0	2.3 ± 1.7	81 ± 17	-4.4
2.1.21.01.	Influenza virus matrix protein M1	1aa7	Influenza virus	Viral	2	0	2.6 ± 0.8	89 ± 4	-5.6
2.1.21.02.	Matrix protein p10, myristoylated	2lpy	Mason-Pfizer monkey virus	Viral	1	0	3.2 ± 0.5	8 ± 6	-3.4
2.1.21.02.	Matrix protein p10	2f76	Mason-Pfizer monkey virus	Viral	1	0	3.9 ± 1.2	48 ± 5	-5.8
2.1.21.03.	Matrix protein p15	1mn8	Moloney murine leukemia virus	Endosome	1	0	1.5 ± 1.8	65 ± 24	-3.5
2.1.21.04.	Matrix protein p19	1a6s	Rous sarcoma virus	Viral	1	0	3.1 ± 2.7	89 ± 14	-3.6
2.1.21.05.	Matrix protein p15	1hek	Equine infectious anemia virus	Endosome	1	0	1.0 ± 2.8	76 ± 21	-2.6
2.1.22.01.