PDB ID or protein name

All proteins in OPM (868 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
1.1.01.01. Sensory rhodopsin II, monomer 1h68 Natronomonas pharaonis Archaebac. 1 7 31.6 ± 2.5 12 ± 5 -76.2
1.1.01.01. Sensory Rhodopsin 1xio Anabaena sp. Bact. gram-neg inner 1 7 31.2 ± 2.8 8 ± 6 -71.7
1.1.01.01. Bacteriorhodopsin, monomer 1py6 Halobacterium salinarum Archaebac. 1 7 31.0 ± 2.5 13 ± 6 -75.9
1.1.01.01. Archaerhodopsin-2, trimeric 2ei4 Halobacterium sp. Archaebac. 3 21 30.1 ± 0.9 0 ± 1 -158.4
1.1.01.01. Xanthorhodopsin 3ddl Salinibacter ruber Bact. gram-neg inner 1 7 26.0 ± 1.5 14 ± 3 -68.2
1.1.01.01. Archaerhodopsin-2 1vgo Halobacterium sp. Archaebac. 1 7 30.8 ± 1.5 9 ± 4 -81.8
1.1.01.01. Bacteriorhodopsin, trimer 1m0l Halobacterium salinarum Archaebac. 3 21 30.0 ± 1.1 0 ± 1 -149.5
1.1.01.01. Sensory rhodopsin II 1h2s Natronomonas pharaonis Archaebac. 4 18 29.5 ± 1.1 0 ± 2 -160.0
1.1.01.01. Halorhodopsin 1e12 Halobacterium salinarum Archaebac. 3 21 30.9 ± 1.8 0 ± 1 -151.6
1.1.01.01. Archaerhodopsin-1 1uaz Halobacterium sp. Archaebac. 1 7 31.7 ± 2.2 6 ± 4 -73.9
1.1.01.02. Beta1-adrenergic receptor 2vt4 Meleagris gallopavo Eukaryo. plasma 1 7 32.7 ± 1.5 6 ± 4 -95.7
1.1.01.02. Rhodopsin 1gzm Bos taurus Eukaryo. plasma 1 7 32.4 ± 1.7 8 ± 3 -91.3
1.1.01.02. Opsin, complex with C-terminal peptide of Galpha subunit of transducin 3dqb Bos taurus Eukaryo. plasma 1 7 31.5 ± 1.4 6 ± 3 -86.3
1.1.01.02. Opsin, retinal-free state 3cap Bos taurus Eukaryo. plasma 1 7 31.4 ± 1.3 6 ± 4 -86.0
1.1.01.02. Melanocortin-4 receptor model (active state) with agonist NDP-MSH 2iqr Homo sapiens Eukaryo. plasma 1 7 34.5 ± 1.5 18 ± 3 -80.2
1.1.01.02. Beta2-adrenergic receptor 2rh1 Homo sapiens Eukaryo. plasma 1 7 31.4 ± 1.3 8 ± 3 -84.3
1.1.01.02. Cholecystokinin A receptor fragment 1d6g Homo sapiens Eukaryo. plasma 2 0 8.0 ± 0.8 89 ± 7 -16.1
1.1.01.02. Melanocortin-4 receptor model (inactive state) with antagonist AGRP 2iqv Homo sapiens Eukaryo. plasma 1 7 33.5 ± 1.5 19 ± 3 -75.3
1.1.01.02. Rhodopsin, a photobleached state 2i37 Bos taurus Eukaryo. plasma 1 7 31.9 ± 1.4 5 ± 4 -88.6
1.1.01.02. Mu-opioid receptor model in active state with agonist 2iqo Rattus norvegicus Eukaryo. plasma 1 7 35.3 ± 1.6 1 ± 4 -95.7
1.1.01.02. A2A adenosine receptor bound to antagonist ZM241385 3eml Homo sapiens Eukaryo. plasma 1 7 33.2 ± 2.2 8 ± 4 -85.1
1.1.01.02. TM1-TM2 fragment of fungal STE2 receptor 2k9p Saccharomyces cerevisiae Eukaryo. plasma 1 2 31.5 ± 2.0 5 ± 7 -25.7
1.1.01.02. Rhodopsin, a dimer 2i36 Bos taurus Eukaryo. plasma 2 14 30.5 ± 1.4 0 ± 1 -161.5
1.1.01.02. Mu-opioid receptor model (inactive state) with antagonist 2iql Rattus norvegicus Eukaryo. plasma 1 7 35.0 ± 1.0 9 ± 3 -97.7
1.1.01.02. Squid rhodopsin dimer 2z73 Todarodes pacificus Eukaryo. plasma 2 14 33.5 ± 1.1 0 ± 2 -167.5
1.1.02.01. Photosynthetic reaction center 1eys Thermochromatium tepidum Bact. gram-neg inner 3 11 30.0 ± 1.5 4 ± 1 -133.8
1.1.02.01. Photosynthetic reaction center 1rzh Rhodobacter sphaeroides Bact. gram-neg inner 3 11 30.0 ± 1.2 5 ± 1 -141.0
1.1.02.01. Photosynthetic reaction center 1dxr Rhodopseudomonas viridis Bact. gram-neg inner 3 11 30.5 ± 1.8 6 ± 1 -138.5
1.1.02.02. Photosystem I 1jb0 Thermosynechococcus elongatus Thylakoid 9 32 32.0 ± 0.8 1 ± 1 -345.1
1.1.02.02. Photosystem I 2o01 Pisum sativum Thylakoid 16 43 27.5 ± 0.5 3 ± 1 -791.8
1.1.02.03. Photosystem II 3bz1 Thermosynechococcus elongatus Thylakoid 34 72 31.2 ± 0.6 0 ± 1 -513.1
1.1.03.01. Light-harvesting complex LH3 1ijd Rhodopseudomonas acidophila Bact. gram-neg inner 18 18 26.2 ± 0.8 0 ± 0 -205.4
1.1.03.01. Light-harvesting complex 1lgh Rhodospirillum molischianum Bact. gram-neg inner 16 16 28.7 ± 0.9 0 ± 1 -187.3
1.1.03.01. Light-harvesting complex LH2 1nkz Rhodopseudomonas acidophila Bact. gram-neg inner 18 18 27.8 ± 0.8 0 ± 0 -246.8
1.1.03.02. Light-Harvesting Complex II 2bhw Pisum sativum Thylakoid 3 9 28.0 ± 1.0 0 ± 1 -160.4
1.1.03.02. Light-Harvesting Complex II 1rwt Spinacia oleracea Thylakoid 3 9 28.0 ± 1.3 0 ± 1 -198.2
1.1.04.01. Cytochrome b6f 2e74 Mastigocladus laminosus Thylakoid 16 26 31.5 ± 0.8 0 ± 1 -291.2
1.1.04.01. Cytochrome bc1, mitochondrial 1pp9 Bos taurus Mitochon. inner 10 26 26.1 ± 0.5 0 ± 5 -208.6
1.1.04.01. Cytochrome b6f 2zt9 Nostoc sp. Thylakoid 16 26 31.0 ± 1.0 0 ± 1 269.6
1.1.04.01. Cytochrome bc1, mitochondrial 1bcc Gallus gallus Mitochon. inner 10 24 26.1 ± 1.0 0 ± 1 -203.0
1.1.04.01. Cytochrome bc1, mitochondrial 1l0l Bos taurus Mitochon. inner 12 26 26.8 ± 0.6 0 ± 0 -241.6
1.1.04.01. Cytochrome bc1, mitochondrial 1kb9 Saccharomyces cerevisiae Mitochon. inner 10 24 26.0 ± 0.8 0 ± 0 -219.4
1.1.04.01. Cytochrome b6f 1q90 Chlamydomonas reinhardtii Thylakoid 16 26 32.5 ± 0.9 0 ± 1 -261.7
1.1.04.01. Cytochrome bc1, bacterial 2fyn Rhodobacter sphaeroides Bact. gram-neg inner 6 20 27.7 ± 1.2 1 ± 1 -195.3
1.1.04.02. Formate dehydrogenase 1kqf Escherichia coli Bact. gram-neg inner 6 15 32.7 ± 1.1 0 ± 2 -174.0
1.1.04.03. Respiratory Nitrate Reductase 1q16 Escherichia coli Bact. gram-neg inner 2 10 29.5 ± 1.0 0 ± 2 -150.6
1.1.04.04. Fumarate reductase 2bs3 Wolinella succinogenes Bact. gram-neg inner 2 10 30.0 ± 1.0 0 ± 1 -131.9
1.1.04.04. Fumarate reductase 2bs2 Wolinella succinogenes Bact. gram-neg inner 2 10 29.7 ± 0.8 0 ± 1 -128.8
1.1.04.05. Succinate dehydrogenase (mitochondrial respiratory complex II) 1zoy Sus scrofa Mitochon. inner 2 6 28.0 ± 2.2 12 ± 3 -75.1
1.1.04.05. Fumarate reductase 1kf6 Escherichia coli Bact. gram-neg inner 2 6 30.0 ± 1.8 10 ± 5 -84.5
1.1.04.05. Succinate dehydrogenase (mitochondrial respiratory complex II) 1yq3 Gallus gallus Mitochon. inner 2 6 33.5 ± 1.2 6 ± 2 -72.0
1.1.04.05. Succinate dehydrogenase 1nek Escherichia coli Bact. gram-neg inner 6 18 32.0 ± 1.0 0 ± 1 -203.1
1.1.05.01. Ubiquinol Oxidase 1fft Escherichia coli Bact. gram-neg inner 3 19 29.0 ± 1.2 3 ± 1 -122.9
1.1.05.01. Bacterial cytochrome c oxidase 1ar1 Paracoccus denitrificans Bact. gram-neg inner 2 14 33.5 ± 2.0 9 ± 2 -129.0
1.1.05.01. Mitochondrial cytochrome c oxidase 1v55 Bos taurus Mitochon. inner 20 56 25.4 ± 1.8 0 ± 2 -245.1
1.1.05.01. Bacterial cytochrome c oxidase 1m56 Rhodobacter sphaeroides Bact. gram-neg inner 4 22 30.5 ± 0.7 2 ± 0 -201.7
1.1.05.01. Bacterial cytochrome c oxidase 1qle Paracoccus denitrificans Bact. gram-neg inner 4 22 31.2 ± 1.5 3 ± 1 -208.8
1.1.05.01. Bacterial cytochrome c oxidase 1ehk Thermus thermophilus Bact. gram-neg inner 3 15 30.4 ± 1.3 5 ± 2 -135.6
1.1.06.01. F1F0 ATP synthase subunit c 1a91 Escherichia coli Bact. gram-neg inner 1 2 36.5 ± 3.2 22 ± 8 -41.4
1.1.06.01. F1F0 ATP synthase 1c17 Escherichia coli Bact. gram-neg inner 13 28 35.9 ± 0.8 2 ± 0 -211.2
1.1.06.01. F-type Sodium ATPase 1yce Ilyobacter tartaricus Bact. gram-neg inner 11 22 37.0 ± 0.8 0 ± 1 -138.3
1.1.06.01. F1F0 ATP synthase subunit c 1wu0 Bacillus ps3 Bact. gram-pos plas. 1 2 32.6 ± 2.3 39 ± 6 -35.6
1.1.06.01. V-type Sodium ATPase 2bl2 Enterococcus hirae Bact. gram-neg inner 10 40 36.7 ± 0.8 0 ± 0 -242.5
1.1.06.01. ATP synthase of chloroplast 2w5j Spinacia oleracea Thylakoid 14 28 35.5 ± 1.4 0 ± 1 -148.1
1.1.06.01. F1F0 ATP synthase 2wie Arthrospira platensis Thylakoid 15 30 31.4 ± 0.5 0 ± 1 -157.3
1.1.07.01. Particulate Methane Monooxygenase 3chx Methylosinus trichosporium Bact. gram-neg inner 10 30 28.7 ± 1.0 0 ± 1 -214.0
1.1.07.01. Particulate Methane Monooxygenase 1yew Methylococcus capsulatus Bact. gram-neg inner 9 42 25.0 ± 0.9 0 ± 1 -199.2
1.1.08.01. Calcium ATPase, E1-2Ca state 1su4 Oryctolagus cuniculus Endoplasm. reticulum 1 10 29.0 ± 2.8 23 ± 4 -81.0
1.1.08.01. Calcium ATPase, E2 state (Ca-free) 2agv Oryctolagus cuniculus Endoplasm. reticulum 1 10 30.1 ± 1.8 18 ± 3 -81.8
1.1.08.01. Calcium ATPase, E2-Pi state 1wpg Oryctolagus cuniculus Endoplasm. reticulum 1 10 30.0 ± 1.5 19 ± 2 -89.9
1.1.08.01. Calcium ATPase, E1-ATP state 1t5s Oryctolagus cuniculus Endoplasm. reticulum 1 10 27.0 ± 1.2 24 ± 1 -80.4
1.1.08.01. Calcium ATPase, E2-Pi state, alternative conformation 3b9b Oryctolagus cuniculus Endoplasm. reticulum 1 10 28.0 ± 1.5 15 ± 2 -80.4
1.1.08.01. Sodium-potassium pump, E2-Pi state 2zxe Squalus acanthias Eukaryo. plasma 3 13 30.1 ± 1.8 8 ± 2 -115.7
1.1.08.01. Calcium ATPase, E1P-ADP state 1wpe Oryctolagus cuniculus Endoplasm. reticulum 1 10 30.5 ± 1.0 19 ± 1 -79.1
1.1.08.01. Sodium-potassium pump, E2-Pi state 3b8e Sus scrofa Eukaryo. plasma 3 12 30.0 ± 1.0 12 ± 2 -121.1
1.1.08.01. Plasma membrane proton pump, E1-ATP state 3b8c Arabidopsis thaliana Eukaryo. plasma 1 10 27.5 ± 1.8 11 ± 3 -69.4
1.1.09.01. ABC transporter permease HI1471 2nq2 Haemophilus influenzae Bact. gram-neg inner 2 20 31.5 ± 1.4 1 ± 3 -148.2
1.1.09.01. ABC transporter BtuCD 1l7v Escherichia coli Bact. gram-neg inner 2 22 29.1 ± 1.0 0 ± 2 -142.8
1.1.09.01. ABC-transporter BtuCD in complex with BtuF 2qi9 Escherichia coli Bact. gram-neg inner 2 22 27.3 ± 1.1 4 ± 2 -140.7
1.1.09.02. Multidrug ABC transporter SAV1866, closed state 2hyd Staphylococcus aureus Bact. gram-pos plas. 2 12 34.5 ± 2.0 0 ± 2 -135.0
1.1.09.02. Lipid flippase MsbA 3b60 Salmonella typhimurium Bact. gram-neg inner 2 12 32.5 ± 0.9 0 ± 1 -111.8
1.1.09.03. Molybdate transporter ModBC, open state 3d31 Methanosarcina acetivorans Archaebac. 2 12 29.3 ± 1.0 1 ± 2 -112.6
1.1.09.03. Molybdate transporter ModBC, open state 2onk Archaeoglobus fulgidus Archaebac. 2 12 35.0 ± 1.3 0 ± 2 -119.0
1.1.09.04. Maltose transporter MalFGK 2r6g Escherichia coli Bact. gram-neg inner 2 14 29.5 ± 2.0 2 ± 3 -121.9
1.1.09.05. Methionine importer MetNI 3dhw Escherichia coli Bact. gram-neg inner 2 10 23.5 ± 2.0 6 ± 5 -78.4
1.1.09.06. P-glycoprotein 3g5u Mus musculus Eukaryo. plasma 1 12 30.6 ± 1.2 3 ± 2 -120.9
1.1.12.01. Preprotein Translocase SecY 1rh5 Methanococcus jannaschii Archaebac. 3 12 28.5 ± 1.0 10 ± 1 -115.4
1.1.12.01. Preprotein translocase SecY 2zjs Thermus thermophilus Bact. gram-neg inner 2 11 26.5 ± 1.0 10 ± 1 -108.4
1.1.12.01. Preprotein Translocase SecY 3din Thermotoga maritima Bact. gram-neg inner 3 13 25.5 ± 1.5 12 ± 2 -82.1
1.1.13.01. Mitochondrial ADP/ATP carrier 1okc Bos taurus Mitochon. inner 1 6 28.0 ± 1.8 5 ± 3 -52.4
1.1.13.01. Mitochondrial ADP/ATP carrier 1ym6 Bos taurus Mitochon. inner 2 7 28.4 ± 1.3 5 ± 3 -62.8
1.1.13.03. Multidrug transporter EmrD 2gfp Escherichia coli Bact. gram-neg inner 1 12 31.8 ± 1.0 11 ± 2 -88.5
1.1.14.01. Glycerol-3-Phosphate Transporter 1pw4 Escherichia coli Bact. gram-neg inner 1 12 31.0 ± 1.4 3 ± 3 -107.8
1.1.14.02. Lactose permease, structure at neutral pH 2cfq Escherichia coli Bact. gram-neg inner 1 12 31.9 ± 1.2 5 ± 3 -113.4
1.1.14.02. Lactose Permease, structure at acidic pH 2cfp Escherichia coli Bact. gram-neg inner 1 12 31.4 ± 1.4 5 ± 3 -111.7
1.1.15.01. Multidrug efflux transporter AcrB with an additional TM helix 2rdd Escherichia coli Bact. gram-neg inner 6 39 26.5 ± 0.8 0 ± 1 -239.0
1.1.15.01. Multidrug efflux transporter AcrB 2gif Escherichia coli Bact. gram-neg inner 3 36 27.5 ± 0.8 2 ± 2 -212.8
1.1.15.01. Multidrug exporter MexB 2v50 Pseudomonas aeruginosa Bact. gram-neg inner 3 36 27.5 ± 0.8 0 ± 1 -189.7
1.1.16.01. Proton Glutamate Symport Protein 2nwl Pyrococcus horikoshii Archaebac. 3 39 26.8 ± 0.9 0 ± 1 -251.0
1.1.17.01. Sodium/proton antiporter 1 (NhaA) 1zcd Escherichia coli Bact. gram-neg inner 1 14 27.5 ± 1.0 4 ± 2 -100.1
1.1.18.01. Leucine transporter LeuT 2a65 Aquifex aeolicus Bact. gram-neg inner 2 28 27.0 ± 0.9 0 ± 1 -170.9
1.1.18.02. Nucleobase-cation symporter-1 2jln Mycobacterium liquefaciens Bact. gram-neg inner 1 12 27.9 ± 1.3 20 ± 1 -114.1
1.1.18.03. Sodium/sugar symporter vSGLT 3dh4 Vibrio parahaemolyticus Bact. gram-neg inner 2 30 27.0 ± 1.2 0 ± 1 -204.4
1.1.18.04. Sodium-betaine symporter BetP 2w8a Corinebacterium glutamicum Bact. gram-neg inner 3 39 27.9 ± 0.8 0 ± 1 -246.7
1.1.18.05. Arginine/agmatine antiporter (AdiC) 3h5m Escherichia coli Bact. gram-neg inner 2 26 34.0 ± 1.4 0 ± 1 -157.3
1.1.18.05. ApcT transporter 3gia Methanococcus jannaschii Archaebac. 1 12 30.6 ± 2.0 15 ± 2 -108.8
1.1.18.05. Arginine/agmatine antiporter (AdiC) 3hqk Salmonella enterica Bact. gram-neg inner 2 26 26.9 ± 1.0 1 ± 2 -155.6
1.1.19.01. Rh-like protein 3b9w Nitrosomonas europaea Bact. gram-neg inner 3 24 29.0 ± 1.0 0 ± 1 -184.6
1.1.19.01. Ammonium transporter Amt-1 2b2f Archaeoglobus fulgidus Archaebac. 3 33 27.5 ± 0.6 0 ± 1 -177.8
1.1.19.01. Rh-like protein 3b9y Nitrosomonas europaea Bact. gram-neg inner 3 33 29.0 ± 1.0 0 ± 1 -184.5
1.1.19.01. Ammonia Channel 1u7g Escherichia coli Bact. gram-neg inner 3 33 28.0 ± 1.0 0 ± 1 -164.4
1.1.19.01. Rhesus Glycoprotein RhCG 3hd6 Homo sapiens Eukaryo. plasma 3 36 30.5 ± 1.1 0 ± 1 -189.3
1.1.21.01. Phospholamban 1zll Homo sapiens Endoplasm. reticulum 5 5 31.5 ± 1.2 0 ± 1 -91.1
1.1.21.01. Sarcolipin 1jdm Homo sapiens Endoplasm. reticulum 1 1 28.9 ± 1.8 1 ± 7 -32.1
1.1.21.02. Na,K-ATPase regulatory protein FXYD1 (phospholemman) 2jo1 Homo sapiens Endoplasm. reticulum 1 1 30.7 ± 2.8 8 ± 3 -34.8
1.1.21.02. Na,K-ATPase regulatory protein FXYD1 (phospholemman) 2jp3 Rattus norvegicus Endoplasm. reticulum 1 1 32.5 ± 1.0 11 ± 6 -31.2
1.1.22.01. Potassium channel KvAP, sensor domain 1ors Aeropyrum pernix Archaebac. 1 5 29.1 ± 2.8 24 ± 3 -65.8
1.1.22.01. Potassium channel KcsA 1r3j Streptomyces lividans Bact. gram-pos plas. 4 12 33.1 ± 1.0 0 ± 2 -119.1
1.1.22.01. Potassium channel Kv1.2. 2a79 Rattus norvegicus Eukaryo. plasma 4 28 26.3 ± 0.8 0 ± 1 -200.6
1.1.22.01. Potassium channel KvAP 1orq Aeropyrum pernix Archaebac. 4 12 26.0 ± 1.5 0 ± 2 -94.0
1.1.22.01. Potassium channel KcsA 1s5h Streptomyces coelicolor Bact. gram-pos plas. 4 12 33.5 ± 1.1 0 ± 2 -125.0
1.1.22.01. Bacterial cyclic nucleotide regulated ion channel 3beh Rhizobium loti Bact. gram-neg inner 4 28 30.2 ± 1.0 0 ± 1 -240.7
1.1.22.01. Potassium channel Kv1.2., structure in a membrane-like environment 2r9r Rattus norvegicus Eukaryo. plasma 4 28 28.5 ± 0.7 0 ± 1 -286.8
1.1.22.01. Potassium channel KvAP 2a0l Aeropyrum pernix Archaebac. 4 12 27.5 ± 1.1 0 ± 1 -141.4
1.1.22.01. Potassium channel KcsA, full-length, closed 3eff Streptomyces lividans Bact. gram-pos plas. 12 12 31.8 ± 1.4 0 ± 1 -126.3
1.1.22.01. Potassium channel, closed state 2ahy Bacillus cereus Bact. gram-pos plas. 4 12 29.2 ± 1.1 0 ± 1 -116.4
1.1.22.01. Potassium channel, open state 3e86 Bacillus cereus Bact. gram-pos plas. 4 12 26.0 ± 1.2 0 ± 1 -101.3
1.1.22.02. Kir3.1-prokaryotic Kir channel chimera 2qks Burkholderia xenovorans Bact. gram-neg inner 4 12 34.0 ± 1.8 0 ± 1 -101.2
1.1.22.02. Potassium channel Kirbac3.1 1xl6 Magnetospirillum magnetotacticum Bact. gram-neg inner 4 12 28.3 ± 1.5 0 ± 2 -89.0
1.1.22.02. Potassium channel Kirbac1.1 1p7b Burkholderia pseudomallei Bact. gram-neg inner 4 12 32.0 ± 0.6 0 ± 1 -145.2
1.1.23.01. Mechanosensitive channel MscL 2oar Mycobacterium tuberculosis Bact. gram-pos plas. 5 10 35.0 ± 1.2 0 ± 1 -157.5
1.1.24.01. Mechanosensitive channel protein MscS, expanded state 2oau Escherichia coli Bact. gram-neg inner 7 14 23.7 ± 0.8 2 ± 2 -181.6
1.1.24.01. Mechanosensitive channel protein MscS, open state 2vv5 Escherichia coli Bact. gram-neg inner 7 21 25.0 ± 0.5 0 ± 0 -162.9
1.1.25.01. CorA magnesium transporter 2bbj Thermotoga maritima Bact. gram-neg inner 5 10 29.1 ± 1.2 0 ± 2 -103.9
1.1.26.01. Acetylcholine receptor 2bg9 Torpedo marmorata Eukaryo. plasma 5 20 31.0 ± 1.6 3 ± 2 -158.0
1.1.26.02. Ligand gated ion channel, active conformation 3eam Gloeobacter violaceus Bact. gram-neg inner 5 20 32.5 ± 1.6 0 ± 1 -196.6
1.1.26.02. Ligand gated ion channel, inactive conformation 2vl0 Erwinia chrysanthemi Bact. gram-neg inner 5 20 35.0 ± 0.8 0 ± 1 -156.4
1.1.27.01. Aquaporin-4 3gd8 Homo sapiens Eukaryo. plasma 4 32 27.9 ± 1.1 0 ± 1 -154.3
1.1.27.01. Aquaglyceroporin 3c02 Plasmodium falciparum Eukaryo. plasma 4 32 31.0 ± 1.6 0 ± 1 -155.3
1.1.27.01. Aquaporin-0, open state 2b6p Bos taurus Eukaryo. plasma 4 32 28.3 ± 0.9 0 ± 1 -146.5
1.1.27.01. Aquaporin-4 2d57 Rattus norvegicus Eukaryo. plasma 4 32 29.8 ± 1.1 0 ± 1 -154.5
1.1.27.01. Aquaporin Z 1rc2 Escherichia coli Bact. gram-neg inner 4 32 27.5 ± 1.5 0 ± 2 -149.6
1.1.27.01. Glycerol uptake facilitator 1ldf Escherichia coli Bact. gram-neg inner 4 32 26.6 ± 0.8 0 ± 0 -167.6
1.1.27.01. Aquaporin-5 3d9s Homo sapiens Eukaryo. plasma 4 32 29.5 ± 1.2 0 ± 1 -160.3
1.1.27.01. Aquaporin-0 2b6o Ovis aries Eukaryo. plasma 4 32 30.5 ± 1.2 0 ± 1 -169.9
1.1.27.01. Aquaporin-1 1j4n Bos taurus Eukaryo. plasma 4 32 29.2 ± 1.2 0 ± 1 -150.9
1.1.27.01. Aquaporin-1 1h6i Homo sapiens Eukaryo. plasma 4 32 25.0 ± 1.5 0 ± 1 -148.9
1.1.27.01. Aquaporin-0 1ymg Bos taurus Eukaryo. plasma 4 32 29.2 ± 0.9 0 ± 1 -155.3
1.1.27.01. Aquaporin Sopip2 1z98 Spinacia oleracea Eukaryo. plasma 4 32 27.5 ± 1.2 0 ± 1 -140.7
1.1.27.01. Aquaporin Aqpm 2f2b Methanobacterium thermoautotrophicum Archaebac. 4 32 24.0 ± 1.2 0 ± 1 -132.8
1.1.27.01. Aquaporin AQY1 2w2e Pichia pastoris Eukaryo. plasma 4 32 30.0 ± 0.9 0 ± 1 -148.2
1.1.27.01. Aquaporin-0 1sor Ovis aries Eukaryo. plasma 4 32 29.0 ± 1.0 0 ± 1 -153.8
1.1.27.01. Aquaporin Sopip2, open state 2b5f Spinacia oleracea Eukaryo. plasma 4 32 27.4 ± 1.0 1 ± 1 -144.0
1.1.28.01. Clc chloride channel 1ots Escherichia coli Bact. gram-neg inner 2 28 23.4 ± 1.6 0 ± 4 -135.2
1.1.28.01. Clc chloride channel 1kpl Salmonella typhimurium Bact. gram-neg inner 2 28 22.7 ± 1.8 0 ± 4 -143.0
1.1.29.01. Steryl-sulfatase 1p49 Homo sapiens Endoplasm. reticulum 1 2 32.0 ± 2.8 20 ± 3 -44.1
1.1.30.01. Protease glpG 2nr9 Haemophilus influenzae Bact. gram-neg inner 1 6 22.6 ± 2.0 15 ± 3 -61.8
1.1.30.01. Protease glpG 2ic8 Escherichia coli Bact. gram-neg inner 1 6 28.4 ± 2.0 17 ± 5 -69.3
1.1.31.01. Zeta-zeta dimer of T cell receptor 2hac Homo sapiens Eukaryo. plasma 2 2 32.5 ± 2.0 4 ± 8 -40.3
1.1.32.01. Outer membrane lipoprotein Wza 2j58 Escherichia coli Bact. gram-neg outer 8 8 31.0 ± 1.0 0 ± 1 -127.9
1.1.33.01. Disulfide bond formation protein B 2k74 Escherichia coli Bact. gram-neg inner 1 4 26.0 ± 1.8 26 ± 5 -56.7
1.1.33.01. DsbB - DsbA complex 2zup Escherichia coli Bact. gram-neg inner 1 4 21.5 ± 3.2 23 ± 5 -24.4
1.1.33.01. DsbB - DsbA complex 2hi7 Escherichia coli Bact. gram-neg inner 1 4 23.8 ± 1.5 30 ± 3 -44.1
1.1.33.01. Disulfide bond formation protein B 2zuq Escherichia coli Bact. gram-neg inner 1 4 25.9 ± 2.0 39 ± 5 -48.4
1.1.34.01. Cytochrome c nitrite reductase complex 2j7a Desulfovibrio vulgaris Bact. gram-neg inner 2 2 32.6 ± 1.0 1 ± 3 -66.5
1.1.35.01. Stannin 1zza Homo sapiens Mitochon. outer 1 1 35.4 ± 2.2 23 ± 12 -27.6
1.1.36.01. Domain of glycophorin A 1afo Homo sapiens Eukaryo. plasma 2 2 31.3 ± 2.2 2 ± 10 -51.5
1.1.37.01. Major coat protein 1ifi Bacteriophage fd Secreted 15 15 30.0 ± 1.5 0 ± 1 -40.1
1.1.37.01. Major coat protein 1ifk Bacteriophage f1 Secreted 15 15 29.0 ± 1.2 0 ± 1 -64.1
1.1.37.02. Major coat protein 1ifp Bacteriophage pf3 Secreted 12 12 32.8 ± 0.2 10 ± 0 -107.0
1.1.37.02. Major coat protein 1hgz Bacteriophage ph75 Secreted 15 15 28.3 ± 0.9 11 ± 0 -55.7
1.1.38.01. Type IV pilin 2pil Neisseria gonorrhoeae Secreted 1 1 28.5 ± 3.5 26 ± 13 -33.1
1.1.39.01. Pulmonary surfactant-associated protein C 1spf Sus scrofa Secreted 1 1 32.8 ± 5.8 21 ± 7 -39.8
1.1.40.01. FLAP protein (5-lipoxygenase activator) 2q7r Homo sapiens Endoplasm. reticulum 3 12 22.5 ± 4.7 0 ± 2 -81.4
1.1.40.01. Microsomal prostaglandin E synthase 1 3dww Homo sapiens Endoplasm. reticulum 3 12 33.4 ± 1.8 1 ± 3 -113.3
1.1.40.01. Lekotriene C4 synthase 2uuh Homo sapiens Endoplasm. reticulum 3 12 26.3 ± 1.2 0 ± 1 -58.2
1.1.40.01. Microsomal glutathione S-transferase 1 2h8a Rattus norvegicus Endoplasm. reticulum 3 12 29.5 ± 1.7 0 ± 1 -72.2
1.1.41.01. Magnesium ion transporter-E (MgtE) 2yvx Thermus thermophilus Bact. gram-neg inner 2 10 32.0 ± 1.5 0 ± 2 -95.5
1.1.42.01. Acid-sensing ion channel 2qts Gallus gallus Eukaryo. plasma 3 6 37.5 ± 2.2 13 ± 2 -76.9
1.1.43.01. Ferrous-iron efflux pump fieF 3h90 Escherichia coli Bact. gram-neg inner 2 12 30.0 ± 1.3 0 ± 3 -117.5
1.1.43.01. Ferrous-iron efflux pump fieF 2qfi Escherichia coli Bact. gram-neg inner 2 12 41.2 ± 2.5 0 ± 3 -36.3
1.1.44.01. Site-2 protease (S2P) metalloprotease 3b4r Methanococcus jannaschii Archaebac. 1 6 26.4 ± 2.0 26 ± 4 -84.6
1.1.45.01. M2 transmembrane domain tetramer, open state, ligand-free 3bkd Influenza virus Viral 4 4 24.8 ± 1.4 1 ± 3 -69.3
1.1.45.01. M2 transmembrane domain tetramer, open state, complex with amantadine 3c9j Influenza virus Viral 4 4 25.0 ± 1.0 7 ± 4 -76.5
1.1.45.01. M2 transmembrane domain tetramer, closed state 2rlf Influenza virus Viral 4 4 31.4 ± 1.8 4 ± 7 -79.3
1.1.46.01. Receptor tyrosine kinase EphA1 2k1k Homo sapiens Eukaryo. plasma 2 2 28.4 ± 1.2 0 ± 3 -51.4
1.1.46.01. Receptor tyrosine kinase EphA2 2k9y Homo sapiens Eukaryo. plasma 2 2 36.5 ± 1.5 0 ± 5 -52.8
1.1.46.01. Transmembrane domain of growth factor receptor (EGF) ErbB2 2jwa Homo sapiens Eukaryo. plasma 2 2 33.5 ± 2.2 0 ± 5 -60.5
1.1.47.01. Polysulfide reductase 2vpz Thermus thermophilus Bact. gram-neg inner 2 16 27.3 ± 1.1 0 ± 1 -130.1
1.1.48.01. Anion-specific porin B 2vql Corinebacterium glutamicum Bact. gram-neg outer 1 0 6.2 ± 1.0 85 ± 3 -11.4
1.1.49.01. BNip3 transmembrane domain dimer 2j5d Homo sapiens Mitochon. outer 2 2 28.5 ± 2.0 11 ± 6 -42.4
1.1.49.01. BNip3 transmembrane domain dimer 2ka1 Homo sapiens Mitochon. outer 2 2 34.0 ± 3.0 11 ± 11 -49.7
1.1.50.01. Integrin alphaIIb-beta3 transmembrane complex 2k9j Homo sapiens Eukaryo. plasma 2 2 38.3 ± 2.2 6 ± 11 -71.7
1.1.51.01. Human CD4 2klu Homo sapiens Eukaryo. plasma 1 1 33.9 ± 3.8 12 ± 14 -34.9
1.1.52.01. Connexin 26 gap junction channel (beta-2 protein) 2zw3 Spodoptera frugiperda Eukaryo. plasma 6 24 32.5 ± 1.3 0 ± 1 -170.5
1.1.53.01. Diacylglycerol kinase (DAGK) 2kdc Escherichia coli Bact. gram-neg inner 3 9 33.5 ± 0.0 0 ± 1 -77.1
1.1.54.01. SNARE complex (syntaxin 1A, SNAP-25 and synaptobrevin 2) 3hd7 Rattus norvegicus Eukaryo. plasma 2 2 27.2 ± 2.0 2 ± 7 -41.9
1.1.55.01. Pore-forming haemolysin E (HlyE) 2wcd Escherichia coli Secreted 12 36 31.0 ± 0.5 0 ± 1 -203.1
1.1.56.01. ATP-gated P2X4 ion channel in the closed state 3h9v Danio rerio Eukaryo. plasma 3 6 25.5 ± 1.3 0 ± 2 -67.7
1.2.01.01. Outer membrane protein NspA 1p4t Neisseria meningitidis Bact. gram-neg outer 1 8 24.3 ± 1.9 10 ± 5 -49.3
1.2.01.01. Transmembrane beta-barrel platform protein 2jmm Designed proteins Bact. gram-neg outer 8 8 22.6 ± 1.7 3 ± 5 -34.0
1.2.01.01. Outer membrane protein A from Klebsiella 2k0l Klebsiella pneumoniae Bact. gram-neg outer 1 8 22.2 ± 2.8 14 ± 8 -32.4
1.2.01.01. Outer membrane protein W 2f1v Escherichia coli Bact. gram-neg outer 1 8 25.0 ± 1.5 9 ± 6 -46.0
1.2.01.01. Outer membrane protein A (OMPA) 1qjp Escherichia coli Bact. gram-neg outer 1 8 24.9 ± 2.2 8 ± 6 -36.7
1.2.01.01. Outer membrane protein X (OMPX) 1qj8 Escherichia coli Bact. gram-neg outer 1 8 23.9 ± 1.9 9 ± 9 -36.7
1.2.01.02. Lipid A acylase PagP 1thq Escherichia coli Bact. gram-neg outer 1 8 22.0 ± 2.0 26 ± 3 -38.7
1.2.01.02. Lipid A deacylase PagL 2erv Pseudomonas aeruginosa Bact. gram-neg outer 1 8 23.0 ± 2.0 23 ± 4 -42.3
1.2.01.03. Major outer membrane protein from Thermus thermophilus 3dzm Thermus thermophilus Bact. gram-neg outer 1 8 28.2 ± 1.7 4 ± 5 -59.2
1.2.02.01. Outer membrane protease OmpT 1i78 Escherichia coli Bact. gram-neg outer 1 10 25.8 ± 1.2 3 ± 4 -54.8
1.2.02.02. Outer membrane adhesin/invasin OpcA 1k24 Neisseria meningitidis Bact. gram-neg outer 1 10 25.2 ± 1.6 6 ± 4 -51.9
1.2.03.01. Autotransporter NalP, different conformation 1uyo Neisseria meningitidis Bact. gram-neg outer 1 12 23.2 ± 2.0 7 ± 4 -55.6
1.2.03.01. Serine protease EspP 2qom Escherichia coli Bact. gram-neg outer 1 12 26.1 ± 2.5 8 ± 5 -63.6
1.2.03.01. Autotransporter NalP 1uyn Neisseria meningitidis Bact. gram-neg outer 1 12 25.5 ± 2.2 5 ± 3 -62.2
1.2.04.01. Autotransporter Hia 2gr7 Haemophilus influenzae Bact. gram-neg outer 3 15 21.5 ± 1.5 0 ± 2 -53.8
1.2.04.01. Autotransporter Hia, a different conformation 3emo Haemophilus influenzae Bact. gram-neg outer 3 12 20.9 ± 1.5 1 ± 4 -50.2
1.2.05.01. Outer membrane phospholipase A 1qd6 Escherichia coli Bact. gram-neg outer 1 12 22.2 ± 1.1 0 ± 1 -91.6
1.2.05.01. Outer membrane phospholipase A, monomer 1qd6C Escherichia coli Bact. gram-neg outer 1 12 23.2 ± 1.5 3 ± 3 -52.8
1.2.06.01. Bacterial Nucleoside Transporter Ts 1tly Escherichia coli Bact. gram-neg outer 1 12 23.3 ± 2.2 5 ± 5 -49.1
1.2.07.01. FadL homologue 3dwo Pseudomonas aeruginosa Bact. gram-neg outer 1 14 24.5 ± 1.7 2 ± 3 -63.2
1.2.07.01. Toluene transporter TbuX 3bry Ralstonia pickettii Bact. gram-neg outer 1 14 24.7 ± 1.8 4 ± 4 -65.0
1.2.07.01. Toluene transporter TodX 3bs0 Pseudomonas putida Bact. gram-neg outer 14 14 22.2 ± 1.4 5 ± 3 -65.6
1.2.07.01. Fatty Acid Transporter FadL 1t16 Escherichia coli Bact. gram-neg outer 1 14 24.5 ± 1.5 4 ± 3 -60.0
1.2.08.01. Outer membrane protein G (OMPG), closed state 2iww Escherichia coli Bact. gram-neg outer 1 14 23.4 ± 1.5 1 ± 2 -67.0
1.2.08.01. Outer membrane protein G (OMPG) 2f1c Escherichia coli Bact. gram-neg outer 1 14 23.0 ± 1.3 1 ± 2 -60.3
1.2.08.01. Outer membrane protein G (OMPG), open state 2iwv Escherichia coli Bact. gram-neg outer 1 14 23.7 ± 1.4 2 ± 4 -64.2
1.2.09.01. Porin 1osm Klebsiella pneumoniae Bact. gram-neg outer 3 48 23.5 ± 0.6 0 ± 1 -152.4
1.2.09.01. Anion-selective porin 1e54 Comamonas acidovorans Bact. gram-neg outer 3 48 24.5 ± 1.1 1 ± 1 -161.9
1.2.09.01. Osmoporin OMPC 2j1n Escherichia coli Bact. gram-neg outer 3 48 24.4 ± 0.8 0 ± 1 -144.4
1.2.09.01. Phosphoporin (PhoE) 1pho Escherichia coli Bact. gram-neg outer 3 48 23.3 ± 0.8 0 ± 1 -148.9
1.2.09.01. Osmoporin OMPC, isoform 1 2ixx Escherichia coli Bact. gram-neg outer 3 48 24.9 ± 1.0 0 ± 1 -154.7
1.2.09.01. Porin OmpF 1hxx Escherichia coli Bact. gram-neg outer 3 48 24.2 ± 0.8 0 ± 1 -147.6
1.2.09.01. Osmoporin OMPC, isoform 2 2ixw Escherichia coli Bact. gram-neg outer 3 48 24.5 ± 1.0 0 ± 1 -141.4
1.2.09.02. Porin 2por Rhodobacter capsulatus Bact. gram-neg outer 3 48 22.5 ± 0.9 0 ± 1 -131.3
1.2.09.02. Porin 3prn Rhodopseudomonas blastica Bact. gram-neg outer 3 48 22.2 ± 0.9 0 ± 0 -147.6
1.2.09.03. Porin OprP 2o4v Pseudomonas aeruginosa Bact. gram-neg outer 3 48 23.0 ± 1.4 0 ± 1 -144.4
1.2.10.01. Maltoporin 1af6 Escherichia coli Bact. gram-neg outer 3 54 25.0 ± 0.7 0 ± 0 -151.2
1.2.10.01. Maltoporin 2mpr Salmonella typhimurium Bact. gram-neg outer 3 54 24.0 ± 0.7 0 ± 0 -139.4
1.2.10.01. Sucrose-specific porin 1a0s Salmonella typhimurium Bact. gram-neg outer 3 54 22.5 ± 0.6 0 ± 1 -124.0
1.2.11.01. Outer membrane porin OprD 2odj Pseudomonas aeruginosa Bact. gram-neg outer 1 18 21.3 ± 1.5 6 ± 2 -68.6
1.2.11.01. Protein OpdK 2qtk Pseudomonas aeruginosa Bact. gram-neg outer 1 18 21.8 ± 2.0 5 ± 4 -70.1
1.2.12.01. Filamentous hemagglutinin transporter FhaC 2qdz Bordetella pertussis Bact. gram-neg outer 1 16 22.3 ± 1.1 6 ± 2 -74.5
1.2.13.01. Outer membrane cobalamin transporter BtuB 1nqe Escherichia coli Bact. gram-neg outer 1 22 21.1 ± 1.3 1 ± 1 -79.5
1.2.13.01. Outer membrane cobalamin transporter BtuB, meso form 2guf Escherichia coli Bact. gram-neg outer 22 22 21.5 ± 1.2 2 ± 2 -80.9
1.2.13.01. Outer membrane cobalamin transporter BtuB, complex with TonB 2gsk Escherichia coli Bact. gram-neg outer 1 22 21.7 ± 1.2 2 ± 2 -84.1
1.2.13.01. Outer membrane receptor FauA 3efm Bordetella pertussis Bact. gram-neg outer 1 22 23.0 ± 1.3 4 ± 2 -85.2
1.2.13.02. Ferric enterobactin receptor FepA 1fep Escherichia coli Bact. gram-neg outer 1 22 24.5 ± 1.2 1 ± 2 -93.1
1.2.13.02. Outer membrane transporter FecA 1kmo Escherichia coli Bact. gram-neg outer 1 22 22.9 ± 1.2 4 ± 1 -81.3
1.2.13.02. Fe(III)-pyochelin receptor FptA 1xkw Pseudomonas aeruginosa Bact. gram-neg outer 1 22 23.0 ± 1.3 4 ± 2 -92.7
1.2.13.02. Pyoverdine Outer Membrane Receptor FpvA 2iah Pseudomonas aeruginosa Bact. gram-neg outer 1 22 22.5 ± 1.2 3 ± 2 -85.8
1.2.13.02. Hemophore receptor HasR 3csl Serratia marcescens Bact. gram-neg outer 1 22 23.0 ± 1.3 1 ± 3 -80.6
1.2.13.02. Ferric hydroxamate uptake receptor FhuA, complex with TonB 2grx Escherichia coli Bact. gram-neg outer 1 22 24.5 ± 0.7 2 ± 2 -88.9
1.2.13.02. Colicin I receptor complex with binding domain of Colicin Ia 2hdi Escherichia coli Bact. gram-neg outer 1 22 22.5 ± 1.3 1 ± 2 -81.2
1.2.13.02. Colicin I receptor 2hdf Escherichia coli Bact. gram-neg outer 1 22 22.0 ± 1.4 2 ± 2 -81.1
1.2.13.02. Outer membrane heme transporter ShuA 3fhh Shigella dysenteriae Bact. gram-neg outer 1 22 23.0 ± 1.3 2 ± 2 -75.4
1.2.13.02. Ferric hydroxamate uptake receptor FhuA 1qfg Escherichia coli Bact. gram-neg outer 1 22 23.5 ± 1.0 0 ± 1 -86.9
1.2.13.02. Outer membrane transporter FecA, different conformation 1kmp Escherichia coli Bact. gram-neg outer 1 22 24.6 ± 1.2 3 ± 2 -85.4
1.2.14.01. Outer membrane protein TolC 1ek9 Escherichia coli Bact. gram-neg outer 3 12 25.0 ± 1.5 0 ± 4 -61.7
1.2.14.01. Multidrug Resistance (VceC) protein 1yc9 Vibrio cholerae Bact. gram-neg outer 3 12 23.5 ± 1.2 0 ± 1 -60.8
1.2.14.01. Drug-Discharge Outer Membrane Protein, OprM 1wp1 Pseudomonas aeruginosa Bact. gram-neg outer 3 12 25.0 ± 2.8 0 ± 2 -63.3
1.2.15.01. Alpha-hemolysin 7ahl Staphylococcus aureus Secreted 7 14 24.5 ± 1.3 0 ± 1 -65.1
1.2.15.02. Porin MspA 1uun Mycobacterium smegmatis Bact. gram-pos cell wall 8 16 43.8 ± 0.9 0 ± 2 -137.1
1.2.16.01. P pilus usher PapC translocation domain 2vqi Escherichia coli Bact. gram-neg outer 1 24 18.4 ± 1.3 5 ± 2 -63.8
1.2.17.01. VDAC-1 channel 2k4t Homo sapiens Mitochon. outer 1 19 20.6 ± 1.1 1 ± 2 -40.6
1.2.17.01. VDAC-1 channel 2jk4 Homo sapiens Mitochon. outer 1 19 20.4 ± 2.1 5 ± 5 -51.9
1.2.17.01. VDAC-1 channel 3emn Mus musculus Mitochon. outer 1 19 22.5 ± 1.3 2 ± 2 -62.6
1.2.18.01. Lipid A deacylase LpxR 3fid Salmonella typhimurium Bact. gram-neg outer 1 12 27.4 ± 3.0 13 ± 6 -61.5
1.2.19.01. Acidic sugar-specific porin NanC 2wjr Escherichia coli Bact. gram-neg outer 1 12 19.0 ± 1.5 9 ± 5 -45.6
2.1.01.01. Snake phospholipase A2, group I 1poa Naja naja atra Secreted 1 0 4.5 ± 1.3 86 ± 12 -5.4
2.1.01.01. Snake phospholipase A2, group I 1ae7 Notechis scutatus scutatus Secreted 1 0 4.1 ± 0.9 82 ± 12 -2.3
2.1.01.01. Snake phospholipase A2, group II, hypotensive 1umv Bothrops jararacussu Secreted 1 0 4.1 ± 0.9 86 ± 8 -4.7
2.1.01.01. Phospholipase A2, group IB 4p2p Sus scrofa Secreted 1 0 3.5 ± 0.7 82 ± 8 -8.7
2.1.01.01. Phospholipase A2 bothropstoxin-2 2oqd Bothrops jararacussu Secreted 1 0 3.5 ± 1.0 80 ± 7 -3.1
2.1.01.01. Phospholipase A2, group IB 5p2p Sus scrofa Secreted 1 0 1.4 ± 1.3 89 ± 7 -2.4
2.1.01.01. Snake phospholipase A2, group I, acidic 2 1m8t Ophiophagus hannah Secreted 1 0 4.5 ± 1.4 86 ± 12 -3.3
2.1.01.01. Snake phospholipase A2, group II, RVV-VD 1vip Vipera russelli Secreted 1 0 3.7 ± 0.5 86 ± 8 -7.6
2.1.01.01. Myotoxin 1god Bothrops godmani Secreted 1 0 3.2 ± 1.3 74 ± 9 -6.3
2.1.01.01. Phospholipase A2, group X 1le6 Homo sapiens Secreted 1 0 7.7 ± 0.4 79 ± 4 -21.8
2.1.01.01. Snake phospholipase A2, group I 1s6b Naja sagittifera Secreted 1 0 2.4 ± 0.8 85 ± 13 -2.3
2.1.01.01. Snake phospholipase A2, group II 1pp2 Crotalus atrox Secreted 1 0 4.7 ± 0.9 83 ± 6 -13.4
2.1.01.01. Snake phospholipase A2, group II 1jlt Vipera ammodytes meridionalis Secreted 1 0 2.6 ± 1.1 85 ± 9 -4.4
2.1.01.01. Snake phospholipase A2-3, group II 1gmz Bothrops pirajai Secreted 1 0 3.2 ± 1.5 82 ± 14 -2.4
2.1.01.01. Snake phospholipase A2, group I, acidic 1 1gp7 Ophiophagus hannah Secreted 1 0 3.4 ± 1.4 85 ± 13 -3.2
2.1.01.01. Snake phospholipase A2, group II, acidic 1bk9 Agkistrodon halys pallas Secreted 1 0 5.8 ± 0.9 79 ± 10 -8.7
2.1.01.01. Snake phospholipase A2, group II 1oz6 Echis carinatus Secreted 1 0 6.0 ± 0.8 88 ± 8 -7.2
2.1.01.01. Snake phospholipase A2, group I 1ozy Micropechis ikaheka Secreted 1 0 3.5 ± 1.1 79 ± 7 -6.8
2.1.01.01. Snake phospholipase A2, group II, B 1jia Agkistrodon halys pallas Secreted 1 0 3.1 ± 1.1 71 ± 10 -8.7
2.1.01.01. Snake phospholipase A2, group I, isoform 2 1u4j Bungarus caeruleus Secreted 1 0 2.1 ± 1.0 79 ± 16 -4.4
2.1.01.01. Myotoxin II 1xxs Bothrops moojeni Secreted 1 0 4.7 ± 1.0 75 ± 8 -5.8
2.1.01.01. Phospholipase A2 homolog, ammodytin L 3dih Vipera ammodytes ammodytes Secreted 1 0 4.1 ± 0.8 79 ± 3 -13.2
2.1.01.01. Snake phospholipase A2, group II, neutral 1bjj Agkistrodon halys pallas Secreted 1 0 2.1 ± 1.0 89 ± 7 -4.2
2.1.01.01. Snake phospholipase A2, group I, KPA2 1g2x Bungarus caeruleus Secreted 1 0 5.0 ± 1.1 67 ± 15 -2.7
2.1.01.01. Snake phospholipase A2, group II, VRV-PL-VIIIa 1zwp Daboia russelli pulchella Secreted 1 0 5.4 ± 0.6 76 ± 6 -12.2
2.1.01.01. Snake phospholipase A2, group II 1vap Agkistridon piscivorus Secreted 1 0 4.3 ± 0.6 89 ± 7 -10.2
2.1.01.01. Snake phospholipase A2, group II (ecarpholin S) 2qhd Echis carinatus Secreted 1 0 7.1 ± 0.4 78 ± 3 -9.0
2.1.01.01. Snake phospholipase A2, group I, isoform 1 1tc8 Bungarus caeruleus Secreted 1 0 1.5 ± 1.6 63 ± 16 -1.8
2.1.01.01. Phospholipase A2, group IIA 1n28 Homo sapiens Secreted 1 0 4.8 ± 0.9 87 ± 5 -6.6
2.1.01.01. Myotoxin 1s8i Agkistrodon contortrix laticinctus Secreted 1 0 4.9 ± 0.6 84 ± 6 -4.5
2.1.01.01. Snake phospholipase A2 2i0u Vipera nikolskii Secreted 1 0 8.4 ± 1.0 88 ± 4 -12.5
2.1.01.01. Myotoxin 1mc2 Agkistrodon acutus Secreted 1 0 3.6 ± 0.6 74 ± 5 -8.1
2.1.01.01. Phospholipase A2, group IB 1g4i Bos taurus Secreted 1 0 2.6 ± 0.9 89 ± 10 -1.8
2.1.01.01. Phospholipase A2 BnSP-7 1pa0 Bothrops neuwiedi pauloensis Secreted 1 0 3.7 ± 1.2 70 ± 12 -5.8
2.1.01.02. Phospholipase A2 1poc Apis mellifera Secreted 1 0 5.7 ± 0.8 60 ± 10 -10.3
2.1.01.03. Prokaryotic phospholipase A2 1kp4 Streptomyces violaceoruber Secreted 1 0 2.0 ± 1.2 60 ± 16 -2.9
2.1.02.01. 12S-Lipoxygenase 3d3l Homo sapiens Eukaryo. plasma 1 0 4.5 ± 0.2 51 ± 5 -6.9
2.1.02.01. Arachidonate 15-Lipoxygenase 2p0m Oryctolagus cuniculus Eukaryo. plasma 1 0 8.4 ± 0.1 87 ± 1 -14.7
2.1.02.01. 8R-Lipoxygenase 1zq4 Plexaura homomalla Eukaryo. plasma 1 0 5.9 ± 2.0 87 ± 19 -5.0
2.1.03.01. Phospholipase C 1p6d Bacillus cereus Secreted 1 0 3.4 ± 1.4 51 ± 10 -4.8
2.1.03.01. Alpha-toxin 1olp Clostridium absonum Secreted 1 0 3.3 ± 1.3 63 ± 10 -4.8
2.1.03.01. Alpha-toxin, different strain 1kho Clostridium perfringens Secreted 1 0 1.3 ± 1.0 89 ± 10 -1.4
2.1.03.01. Alpha-toxin, closed state (inactive) 1gyg Clostridium perfringens Secreted 1 0 5.5 ± 1.3 60 ± 18 -4.2
2.1.03.01. Alpha-toxin, open state 1ca1 Clostridium perfringens Secreted 1 0 2.2 ± 1.0 88 ± 5 -4.5
2.1.04. Phospholipase A2 homolog 2wg7 Oryza sativa (Rice) Secreted 1 0 3.9 ± 1.3 78 ± 10 -8.3
2.1.04.01. Prostaglandin H2 synthase-1 1q4g Ovis aries Endoplasm. reticulum 2 0 7.2 ± 0.3 87 ± 5 -37.8
2.1.04.01. Prostaglandin H2 synthase-2 1cx2 Mus musculus Endoplasm. reticulum 2 0 10.4 ± 0.4 87 ± 8 -38.3
2.1.05.01. Lanosterol synthase 1w6k Homo sapiens Endoplasm. reticulum 1 0 6.5 ± 0.8 76 ± 3 -19.9
2.1.05.01. Squalene-hopene cyclase 2sqc Alicyclobacillus acidocaldarius Bact. gram-pos plas. 2 0 7.2 ± 0.3 90 ± 2 -23.8
2.1.06.01. Farnesyl diphosphate synthase (Geranyltranstransferase) 1rqj Escherichia coli Bact. gram-neg inner 1 0 5.0 ± 1.7 83 ± 8 -6.1
2.1.07.01. Mammalian cytochrome P450 2c9 1og5 Homo sapiens Endoplasm. reticulum 1 0 7.5 ± 1.0 74 ± 5 -13.6
2.1.07.01. Mammalian cytochrome P450 2d6 2f9q Homo sapiens Endoplasm. reticulum 1 0 8.7 ± 1.4 34 ± 4 -16.8
2.1.07.01. Cytochrome P450 CYP120A1 2ve3 Synechocystis sp. Thylakoid 1 0 6.3 ± 0.5 61 ± 9 -8.1
2.1.07.01. Mammalian cytochrome P450 3a4 1tqn Homo sapiens Endoplasm. reticulum 1 0 10.2 ± 1.0 61 ± 11 -20.7
2.1.07.01. Mammalian cytochrome P450 2b4, open state 1 2bdm Oryctolagus cuniculus Endoplasm. reticulum 1 0 10.5 ± 1.0 45 ± 10 -18.2
2.1.07.01. Mammalian cytochrome P450 1a2 2hi4 Homo sapiens Endoplasm. reticulum 1 0 6.2 ± 1.0 68 ± 5 -16.9
2.1.07.01. Mammalian cytochrome P450 19a1 (aromatase, estrogen synthetase) 3eqm Homo sapiens Endoplasm. reticulum 1 0 5.9 ± 1.3 57 ± 7 -9.7
2.1.07.01. Mammalian cytochrome P450 2a6 1z10 Homo sapiens Endoplasm. reticulum 1 0 6.3 ± 1.0 38 ± 12 -10.3
2.1.07.01. Mammalian cytochrome P450 2c9, different conformation 1r9o Homo sapiens Endoplasm. reticulum 1 0 7.5 ± 1.0 57 ± 10 -10.7
2.1.07.01. Prostacyclin synthase (cytochrome P450 8a1) 3b6h Homo sapiens Endoplasm. reticulum 1 0 4.5 ± 1.0 68 ± 5 -5.5
2.1.07.01. Lanosterol 14-alpha-demethylase (CYP51) 3i3k Homo sapiens Endoplasm. reticulum 1 0 9.4 ± 0.1 53 ± 1 -15.9
2.1.07.01. Mammalian cytochrome P450 3a4, a different conformation 1w0f Homo sapiens Endoplasm. reticulum 1 0 6.2 ± 0.8 68 ± 7 -15.2
2.1.07.01. Mammalian cytochrome P450 2c5, different conformation 1dt6 Oryctolagus cuniculus Endoplasm. reticulum 1 0 7.5 ± 2.0 17 ± 8 -8.4
2.1.07.01. Plant cytochrome P450 74A (allene oxide synthase) 3dan Parthenium argentatum Secreted 1 0 8.5 ± 1.0 69 ± 4 -25.4
2.1.07.01. Mammalian cytochrome P450 2b4, open state 2 1po5 Oryctolagus cuniculus Endoplasm. reticulum 1 0 9.7 ± 0.7 39 ± 5 -6.9
2.1.07.01. Mammalian cytochrome P450 2e1 3e6i Homo sapiens Endoplasm. reticulum 1 0 8.1 ± 0.3 46 ± 5 -14.7
2.1.07.01. Sterol 14-alpha-demethylase (CYP51) 3g1q Trypanosoma brucei Endoplasm. reticulum 1 0 7.3 ± 1.0 61 ± 6 -13.4
2.1.07.01. Mammalian cytochrome P450 2c5 1nr6 Oryctolagus cuniculus Endoplasm. reticulum 1 0 12.5 ± 1.2 54 ± 10 -11.6
2.1.07.01. Mammalian cytochrome P450 2R1 3czh Homo sapiens Endoplasm. reticulum 1 0 9.5 ± 1.8 50 ± 10 -15.5
2.1.07.01. Lanosterol 14-alpha-demethylase (CYP51) 2wuz Trypanasoma cruzi Endoplasm. reticulum 1 0 9.4 ± 1.0 62 ± 6 -12.5
2.1.07.01. Mammalian cytochrome P450 2b4, closed state 1suo Oryctolagus cuniculus Endoplasm. reticulum 1 0 4.7 ± 1.1 54 ± 8 -13.0
2.1.07.01. Mammalian cytochrome P450 46A1 2q9f Homo sapiens Endoplasm. reticulum 0 0 3.7 ± 1.4 80 ± 9 -4.7
2.1.07.01. Mammalian cytochrome P450 2c8 1pq2 Homo sapiens Endoplasm. reticulum 1 0 7.6 ± 0.9 20 ± 10 -9.4
2.1.08.01. Cytochrome c6 1c6s Thermosynechococcus elongatus Thylakoid 1 0 3.3 ± 1.0 77 ± 17 -1.2
2.1.08.01. Cytochrome c6 1f1f Arthrospira maxima Thylakoid 1 0 4.8 ± 1.3 79 ± 14 -3.4
2.1.08.01. Cytochrome c6 1ls9 Cladophora glomerata Thylakoid 1 0 2.0 ± 1.6 85 ± 18 -1.9
2.1.08.01. Cytochrome c552 1a8c Nitrosomonas europaea Bact. gram-neg inner 1 0 2.2 ± 1.1 60 ± 16 -4.0
2.1.08.01. Cytochrome c2 1co6 Rhodopseudomonas viridis Bact. gram-neg inner 1 0 1.1 ± 1.0 78 ± 10 -2.8
2.1.08.01. Mono-heme c-type cytochrome ScyA 1kx7 Shewanella putrefaciens Bact. gram-neg inner 1 0 2.3 ± 1.7 73 ± 18 -3.0
2.1.08.01. Cytochrome c2 1cxa Rhodobacter sphaeroides Bact. gram-neg inner 1 0 2.1 ± 1.0 89 ± 8 -1.7
2.1.08.01. Mitochondrial cytochrome c 1hrc Equus caballus Mitochon. inner 1 0 1.9 ± 1.2 72 ± 13 -2.0
2.1.08.01. Cytochrome c551 1cor Pseudomonas stutzeri Bact. gram-neg inner 1 0 3.3 ± 1.1 40 ± 11 -7.5
2.1.08.01. Cytochrome c551 451c Pseudomonas aeruginosa Bact. gram-neg inner 1 0 3.5 ± 1.3 85 ± 15 -5.0
2.1.08.02. Cytochrome c4 1m70 Pseudomonas stutzeri Bact. gram-neg inner 1 0 4.6 ± 0.8 69 ± 8 -5.1
2.1.09.01. Major allergen I 1puo Felis catus Secreted 1 0 3.7 ± 1.1 61 ± 11 -7.1
2.1.10.01. Glycolipid transfer protein 1tfj Bos taurus Eukaryo. plasma 1 0 2.8 ± 1.5 85 ± 12 -5.6
2.1.10.01. Glycolipid transfer protein, bound form 1sx6 Homo sapiens Eukaryo. plasma 1 0 3.9 ± 1.0 87 ± 7 -7.9
2.1.10.01. Glycolipid transfer protein, apo-form 1swx Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.3 86 ± 9 -4.9
2.1.11.01. Spectrin alpha chain 2spc Drosophila melanogaster Eukaryo. plasma 2 0 1.6 ± 1.0 87 ± 15 -3.5
2.1.11.01. Alpha-actinin-2 1hci Homo sapiens Eukaryo. plasma 2 0 1.5 ± 1.0 90 ± 5 -3.4
2.1.12.01. Outer surface protein C 1g5z Borrelia burgdorferi Bact. gram-neg outer 2 0 4.0 ± 0.5 0 ± 15 -6.1
2.1.13.01. Molt-inhibiting hormone 1j0t Marsupenaeus japonicus Secreted 1 0 3.2 ± 0.6 62 ± 14 -5.4
2.1.14.01. Mitochondria fission protein Fis1 1nzn Homo sapiens Mitochon. outer 1 0 6.1 ± 1.6 77 ± 14 -5.6
2.1.14.01. Vesicular transport protein sec17 1qqe Saccharomyces cerevisiae Vacuole 1 0 7.9 ± 2.0 73 ± 3 -7.1
2.1.14.01. Nucleoside transporter 2 (water-soluble domain) 1hxi Trypanosoma brucei Eukaryo. plasma 1 0 6.8 ± 1.0 52 ± 5 -4.9
2.1.15.01. Epsin-1 (ENTH domain) 1h0a Rattus norvegicus Eukaryo. plasma 1 0 2.9 ± 1.1 58 ± 13 -5.2
2.1.15.02. Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) 1dvp Drosophila melanogaster Endosome 2 0 2.6 ± 0.3 90 ± 5 -6.5
2.1.15.03. Clathrin assembly lymphoid myeloid leukemia (CALM) protein 1hfa Rattus norvegicus Eukaryo. plasma 1 0 2.0 ± 2.0 52 ± 7 -3.9
2.1.16.01. E2 domain of amyloid beta A4 protein precursor 1rw6 Homo sapiens Eukaryo. plasma 8 0 7.5 ± 6.0 55 ± 5 -9.6
2.1.17.01. Inner nuclear membrane protein emerin 1jei Homo sapiens Nuclear inner 1 0 6.3 ± 1.5 86 ± 14 -3.8
2.1.17.01. Lamina-associated polypeptide 2 isoform alpha 1h9f Homo sapiens Nuclear inner 1 0 2.6 ± 1.5 46 ± 18 -3.7
2.1.18.01. Annexin VI 1m9i Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.2 83 ± 6 -5.6
2.1.18.01. Annexin VIII 1w3w Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.6 76 ± 12 -5.1
2.1.18.01. Annexin V 1a8a Rattus norvegicus Eukaryo. plasma 3 0 2.5 ± 1.1 90 ± 11 -6.3
2.1.18.01. Annexin XII 1dm5 Hydra vulgaris Eukaryo. plasma 3 0 3.1 ± 1.1 85 ± 4 -8.3
2.1.18.01. Annexin II 1w7b Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.7 86 ± 20 -2.9
2.1.18.01. Annexin 24 1dk5 Capsicum annuum Eukaryo. plasma 1 0 1.8 ± 1.7 86 ± 18 -1.2
2.1.18.01. Annexin III 1axn Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.4 73 ± 12 -4.8
2.1.18.01. Annexin GH1 1n00 Gossypium hirsutum Eukaryo. plasma 1 0 2.6 ± 2.0 64 ± 18 -1.9
2.1.18.01. Annexin IV 1i4a Bos taurus Eukaryo. plasma 3 0 2.2 ± 1.3 88 ± 4 -6.0
2.1.18.01. Annexin IV, monomeric state 1ann Bos taurus Eukaryo. plasma 1 0 2.6 ± 1.4 77 ± 9 -5.8
2.1.18.01. Annexin V 1hvf Homo sapiens Eukaryo. plasma 1 0 2.0 ± 1.4 77 ± 18 -3.3
2.1.18.01. Annexin V 1yii Gallus gallus Eukaryo. plasma 1 0 2.7 ± 1.6 79 ± 12 -2.9
2.1.18.01. Annexin I 1hm6 Sus scrofa Vesicle 1 0 1.7 ± 0.9 90 ± 6 -4.1
2.1.19.01. Apoptosis regulator Bcl-2 1g5m Homo sapiens Mitochon. outer 1 0 4.6 ± 1.6 42 ± 12 -3.9
2.1.20.01. Coagulation factor VIIa 1dan Homo sapiens Eukaryo. plasma 4 0 4.8 ± 1.3 24 ± 15 -5.7
2.1.20.01. Prothrombin 1nl2 Bos taurus Eukaryo. plasma 1 0 4.1 ± 1.6 19 ± 19 -6.2
2.1.20.01. Coagulation factor IX 1pfx Sus scrofa Eukaryo. plasma 2 0 3.2 ± 2.0 76 ± 20 -3.8
2.1.20.01. Coagulation factor XIV (protein C) in complex with its receptor 1lqv Homo sapiens Eukaryo. plasma 2 0 4.2 ± 1.5 49 ± 13 -5.0
2.1.21.01. Influenza virus matrix protein M1 1aa7 Influenza virus Viral 2 0 2.5 ± 1.1 76 ± 10 -3.7
2.1.22.01. Retrovius gp41 protease-resistant core 1df4 Human immunodeficiency virus type 1 Viral 3 0 5.1 ± 1.0 0 ± 10 -4.8
2.1.22.01. Paramyxovirus sv5 fusion protein core 1svf Simian virus 5 Viral 6 0 8.1 ± 1.0 0 ± 10 -16.0
2.1.23.01. Ectatomin 1eci Ectatomma tuberculatum Secreted 2 0 4.1 ± 1.3 41 ± 12 -2.9
2.1.24.01. Pulmonary surfactant-associated protein B fragment 2dwf Homo sapiens Secreted 1 0 3.0 ± 0.6 84 ± 5 -7.9
2.1.24.01. Saposin B, complex with phosphatidylethanolamine 1n69 Homo sapiens Lysosome 6 0 1.6 ± 0.3 90 ± 10 -3.1
2.1.24.02. NK-lysin 1nkl Sus scrofa Secreted 1 0 3.7 ± 1.1 29 ± 11 -4.8
2.1.24.02. Saposin C, structure in micelles 1sn6 Homo sapiens Lysosome 1 0 4.4 ± 0.9 82 ± 7 -4.1
2.1.25.01. Bacteriocin AS-48 1o82 Enterococcus faecalis Secreted 1 0 8.1 ± 1.3 47 ± 14 -6.8
2.1.26.01. Colicin A channel-forming domain 1col Escherichia coli Secreted 1 0 1.0 ± 1.1 42 ± 10 -1.5
2.1.27.01. Cry4Ba 1w99 Bacillus thuringiensis Secreted 1 0 5.1 ± 1.5 89 ± 16 -5.0
2.1.27.01. Cry3A 1dlc Bacillus thuringiensis Secreted 1 0 1.6 ± 2.0 15 ± 17 -1.3
2.1.27.01. Cry3Bb1 1ji6 Bacillus thuringiensis Secreted 2 0 4.5 ± 1.0 89 ± 15 -4.9
2.1.27.01. Cry2Aa 1i5p Bacillus thuringiensis Secreted 1 0 11.7 ± 2.0 7 ± 12 -7.2
2.1.28.01. Heat-stable enterotoxin II 1ehs Escherichia coli Secreted 1 0 2.8 ± 1.7 64 ± 10 -4.5
2.1.29.01. Apolipoprotein A-I 2a01 Homo sapiens Secreted 1 0 2.9 ± 1.8 62 ± 3 -5.9
2.1.30.01. Penicillin-binding protein 1A 2oqo Aquifex aeolicus Bact. gram-neg inner 1 0 5.0 ± 1.4 43 ± 2 -8.4
2.1.30.01. Penicillin-binding protein 1B 3fwm Escherichia coli Bact. gram-neg inner 1 0 10.4 ± 6.0 3 ± 8 -20.3
2.1.30.01. Penicillin-binding protein 2 2olv Staphylococcus aureus Bact. gram-pos cell wall 1 0 5.7 ± 2.0 40 ± 10 -2.7
2.1.30.01. Glycosyltransferase MtgA 3hzs Staphylococcus aureus Bact. gram-pos cell wall 1 0 8.1 ± 0.1 47 ± 3 -13.8
2.1.30.02. Lysozyme 3hde Enterobacteria phage p21 Secreted 1 0 8.3 ± 1.1 26 ± 14 -3.6
2.1.31.01. Colicin-M 3da4 Escherichia coli Bact. gram-neg inner 1 0 10.5 ± 1.6 80 ± 9 -6.4
2.2.01.01. Type 1 signal peptidase, complex with lipopeptide inhibitor 1t7d Escherichia coli Bact. gram-neg inner 1 0 3.7 ± 1.0 66 ± 3 -5.9
2.2.01.01. Type 1 signal peptidase, complex with inhibitor 1b12 Escherichia coli Bact. gram-neg inner 1 0 2.4 ± 2.0 88 ± 18 -2.4
2.2.01.01. Type 1 signal peptidase, apo-enzyme 1kn9 Escherichia coli Bact. gram-neg inner 1 0 4.5 ± 1.2 83 ± 6 -4.5
2.2.02.01. Exfoliative toxin B 1qtf Staphylococcus aureus Secreted 1 0 2.4 ± 1.8 80 ± 10 -3.1
2.2.02.01. Mitochondrial serine protease HtrA2 1lcy Homo sapiens Mitochon. inner 1 0 8.0 ± 1.7 79 ± 15 -4.0
2.2.02.02. Chymotrypsinogen B 1kdq Rattus norvegicus Eukaryo. plasma 1 0 2.8 ± 2.0 75 ± 17 -3.6
2.2.02.02. Procarboxypeptidase A-S6 subunit III 1fon Bos taurus Eukaryo. plasma 2 0 1.4 ± 0.7 88 ± 5 -4.8
2.2.02.03. NS3 protease 1dy9 Human hepatitis C virus Secreted 1 0 6.1 ± 1.8 62 ± 12 -10.5
2.2.02.03. NS3 protease, dimer 1n1l Human hepatitis C virus Secreted 2 0 5.8 ± 1.3 70 ± 9 -10.3
2.2.02.03. NS3 protease, complex with Bowman-Birk inhibitor 1df9 Dengue virus Secreted 3 0 2.1 ± 0.5 88 ± 6 -4.7
2.2.02.03. NS3 protease 1bef Dengue virus Secreted 1 0 3.0 ± 1.1 78 ± 10 -4.1
2.2.03.01. Phytepsin 1qdm Hordeum vulgare Vacuole 1 0 11.2 ± 0.7 85 ± 6 -9.3
2.2.03.01. Plasmepsin IV 1qs8 Plasmodium vivax Vacuole 1 0 8.6 ± 0.8 74 ± 10 -6.9
2.2.03.01. Cathepsin D 1lyb Homo sapiens Lysosome 2 0 5.7 ± 1.0 90 ± 7 -10.6
2.2.04.01. Lignostilbene-alpha,beta-dioxygenase (retinal-forming oxygenase) 2biw Synechocystis sp. Bact. gram-neg inner 1 0 5.1 ± 0.5 40 ± 9 -12.7
2.2.04.01. Retinal pigment epitelium-specific 65 kDa protein 3fsn Bos taurus Eukaryo. plasma 1 0 7.6 ± 0.7 78 ± 5 -7.3
2.2.05.01. Plantacyanin 1f56 Spinacia oleracea Thylakoid 1 0 1.8 ± 2.0 5 ± 19 -1.4
2.2.05.01. Amicyanin 1sfd Paracoccus denitrificans Bact. gram-neg inner 1 0 3.5 ± 0.8 55 ± 8 -3.3
2.2.05.01. Amicyanin 1id2 Paracoccus versutus Bact. gram-neg inner 1 0 3.6 ± 0.6 59 ± 5 -5.3
2.2.05.01. Plastocyanin 9pcy Phaseolus vulgaris Thylakoid 1 0 1.1 ± 1.7 25 ± 17 -1.3
2.2.05.01. Pseudoazurin 1pmy Methylobacterium extorquens Bact. gram-neg inner 1 0 2.5 ± 1.5 43 ± 12 -4.6
2.2.05.01. Plastocyanin 2plt Chlamydomonas reinhardtii Thylakoid 1 0 1.6 ± 1.4 37 ± 19 -1.3
2.2.05.01. Azurin I 1rkr Alcaligenes xylosoxidans Bact. gram-neg inner 1 0 1.7 ± 0.9 43 ± 7 -4.5
2.2.05.01. Plastocyanin 1bxv Synechocystis sp. Thylakoid 1 0 1.7 ± 1.9 36 ± 17 -1.4
2.2.05.01. Azurin iso-2 1cuo Methylomonas sp. Bact. gram-neg inner 1 0 3.3 ± 1.8 50 ± 20 -3.8
2.2.05.01. Plastocyanin 1b3i Prochlorothrix hollandica Thylakoid 1 0 2.3 ± 1.7 42 ± 13 -3.0
2.2.06.01. Outer membrane lipoprotein Blc 1qwd Escherichia coli Bact. gram-neg outer 1 0 1.6 ± 1.2 88 ± 19 -3.0
2.2.06.01. Retinol binding protein 1rbp Homo sapiens Secreted 1 0 3.1 ± 1.5 75 ± 10 -5.8
2.2.06.01. Retinol binding protein 1rlb Gallus gallus Secreted 1 0 2.7 ± 1.0 78 ± 9 -4.4
2.2.06.01. Retinol binding protein, plasma isoform 1iiu Gallus gallus Secreted 1 0 2.3 ± 2.0 40 ± 17 -3.4
2.2.06.01. Retinol binding protein 1kt6 Bos taurus Secreted 1 0 3.5 ± 1.3 79 ± 10 -4.5
2.2.06.01. Retinol binding protein 1aqb Sus scrofa Secreted 1 0 3.4 ± 1.1 81 ± 13 -4.6
2.2.06.02. Myelin p2 protein 1yiv Equus caballus Eukaryo. plasma 1 0 2.1 ± 1.0 46 ± 9 -2.5
2.2.06.02. Intestinal fatty acid binding protein 1kzw Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.2 56 ± 13 -3.1
2.2.06.02. Cellular retinoic acid-binding protein 1 1cbr Bos taurus Eukaryo. plasma 1 0 6.7 ± 1.1 40 ± 10 -3.2
2.2.06.02. Retinol-binding protein 4 1lpj Homo sapiens Secreted 1 0 2.3 ± 1.2 44 ± 15 -5.0
2.2.06.02. Brain fatty acid binding protein 1fdq Homo sapiens Eukaryo. plasma 1 0 3.2 ± 1.0 53 ± 18 -2.2
2.2.06.02. Cellular retinol-binding protein II 1crb Rattus norvegicus Eukaryo. plasma 1 0 2.2 ± 1.2 62 ± 17 -3.3
2.2.06.02. Epidermal fatty acid binding protein 1b56 Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.1 53 ± 15 -2.8
2.2.06.02. Cellular retinol-binding protein II 1kqw Danio rerio Eukaryo. plasma 1 0 2.0 ± 1.5 41 ± 16 -3.4
2.2.06.02. Adipocyte lipid-binding protein 1g7n Mus musculus Eukaryo. plasma 1 0 2.1 ± 1.4 41 ± 18 -2.5
2.2.06.02. Cellular retinol-binding protein III 1ggl Homo sapiens Eukaryo. plasma 1 0 3.5 ± 1.6 43 ± 15 -5.5
2.2.06.02. Adipocyte lipid-binding protein 1tow Homo sapiens Eukaryo. plasma 1 0 1.9 ± 1.8 46 ± 18 -2.6
2.2.06.02. P2 myelin protein 1pmp Bos taurus Eukaryo. plasma 1 0 2.4 ± 1.1 58 ± 17 -3.9
2.2.06.02. Muscle fatty acid binding protein 1hmt Homo sapiens Eukaryo. plasma 1 0 4.4 ± 1.2 45 ± 13 -2.3
2.2.06.02. Fatty acid-binding protein homolog 1 1o8v Echinococcus granulosus Eukaryo. plasma 1 0 2.1 ± 1.4 53 ± 13 -3.5
2.2.06.02. Fatty acid-binding protein Sm14 1vyf Schistosoma mansoni Eukaryo. plasma 1 0 4.2 ± 1.4 48 ± 17 -2.8
2.2.06.02. Muscle fatty acid binding protein 1bwy Bos taurus Eukaryo. plasma 1 0 5.1 ± 1.2 67 ± 12 -5.9
2.2.06.02. Fatty acid-binding protein 1ftp Schistocerca gregaria Eukaryo. plasma 1 0 4.0 ± 1.6 51 ± 15 -4.7
2.2.06.02. Intestinal fatty acid binding protein 1icm Rattus norvegicus Eukaryo. plasma 1 0 3.3 ± 1.2 49 ± 15 -3.3
2.2.06.02. Cellular retinoic acid-binding protein 2 1cbs Homo sapiens Eukaryo. plasma 1 0 6.9 ± 1.3 36 ± 11 -4.9
2.2.07.01. Polyisoprenoid-binding protein 1wub Thermus thermophilus Bact. gram-neg inner 1 0 3.7 ± 2.0 40 ± 11 -5.6
2.2.08.01. Osmotin-like protein 1aun Nicotiana tabacum Secreted 1 0 4.6 ± 1.1 89 ± 7 -4.6
2.2.08.01. Osmotin 1pcv Nicotiana tabacum Secreted 1 0 10.3 ± 1.0 73 ± 5 -2.6
2.2.09.01. Ganglioside GM2 activator 1tjj Homo sapiens Lysosome 1 0 4.6 ± 1.4 55 ± 9 -9.3
2.2.09.01. Ganglioside GM2 activator 2agc Mus musculus Lysosome 1 0 4.5 ± 1.6 47 ± 14 -4.7
2.2.09.01. Ganglioside GM2 activator, different conformation 1pub Homo sapiens Lysosome 1 0 5.2 ± 1.0 44 ± 4 -7.8
2.2.09.01. Ganglioside GM2 activator, apo-protein 2ag4 Homo sapiens Lysosome 1 0 4.2 ± 1.7 47 ± 10 -5.1
2.2.10.01. High potential iron protein 1hpi Ectothiorhodospira vacuolata Bact. gram-neg inner 1 0 3.8 ± 1.2 80 ± 11 -4.7
2.2.11.01. C2 domain of cytosolic phospholipase A2, group IVA 1rlw Homo sapiens Nuclear outer 1 0 5.3 ± 1.9 53 ± 18 -7.1
2.2.11.01. C2 domain of protein kinase C eta 2fk9 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.8 55 ± 16 -2.5
2.2.11.01. C2 domain of protein kinase C delta 1yrk Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.5 56 ± 19 -1.4
2.2.11.01. Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN 1d5r Homo sapiens Eukaryo. plasma 1 0 2.1 ± 1.9 81 ± 11 -2.6
2.2.11.01. C2 domain of protein kinase C delta 1bdy Rattus norvegicus Eukaryo. plasma 1 0 1.2 ± 1.2 69 ± 10 -1.3
2.2.11.01. E3 ubiquitin-protein ligase Itchy homolog 2nq3 Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.0 24 ± 6 -5.7
2.2.11.01. C2 domain of protein kinase C epsilon 1gmi Rattus rattus Eukaryo. plasma 1 0 2.0 ± 1.1 41 ± 10 -5.1
2.2.11.02. Synaptotagmin-1 C2A-C2B domains 2r83 Homo sapiens Eukaryo. plasma 1 0 3.1 ± 1.0 88 ± 11 -3.8
2.2.11.02. C2B domain of synaptotagmin I (Calcium bound) 1uov Rattus norvegicus Eukaryo. plasma 1 0 2.4 ± 1.8 32 ± 18 -4.3
2.2.11.02. Synaptotagmin III 1dqv Rattus norvegicus Eukaryo. plasma 1 0 2.4 ± 1.6 21 ± 19 -3.6
2.2.11.02. C2 domain of rabphilin-3A 2chd Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 1.2 61 ± 9 -1.5
2.2.11.02. Synaptotagmin IV 1ugk Homo sapiens Eukaryo. plasma 1 0 2.4 ± 2.0 44 ± 20 -1.7
2.2.11.02. C2A domain of RIM2 2cjs Rattus norvegicus Eukaryo. plasma 1 0 3.9 ± 2.0 48 ± 16 -4.7
2.2.11.02. C2 domain of protein kinase C beta 1a25 Rattus norvegicus Eukaryo. plasma 1 0 2.2 ± 1.4 38 ± 18 -2.2
2.2.11.02. C2a-domain of Rab3 interacting molecule 2 (RIM2) 2bwq Rattus norvegicus Eukaryo. plasma 1 0 1.4 ± 2.0 39 ± 18 -1.5
2.2.11.02. C2 domain of phosphatidylinositide 3-kinase C2 alpha 2b3r Mus musculus Eukaryo. plasma 2 0 1.8 ± 1.2 40 ± 17 -3.8
2.2.11.02. C2 domain of protein kinase C alpha, complex with phosphatidyl serine 1dsy Rattus norvegicus Eukaryo. plasma 1 0 1.5 ± 1.5 18 ± 9 -2.0
2.2.11.02. C2A domain of synaptotagmin I (Calcium free) 3f00 Homo sapiens Eukaryo. plasma 1 0 1.1 ± 1.1 28 ± 8 -1.8
2.2.11.02. C2A domain of synaptotagmin I (Calcium free) 1rsy Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 1.0 26 ± 6 -3.3
2.2.11.02. C2A domain of synaptotagmin I (Calcium bound) 1byn Rattus norvegicus Eukaryo. plasma 1 0 3.7 ± 2.0 36 ± 20 -4.4
2.2.12.01. Exocyst complex component Sec5, complex with protein RalA from Human 1uad Rattus norvegicus Eukaryo. plasma 2 0 2.0 ± 1.3 41 ± 10 -2.2
2.2.12.02. Epididymal secretory protein E1 1nep Bos taurus Secreted 1 0 7.7 ± 1.0 70 ± 9 -5.3
2.2.12.03. Rho GDP-dissociation inhibitor 1, complex with cell division control protein 42 1doa Homo sapiens Eukaryo. plasma 2 0 1.7 ± 1.7 81 ± 12 -1.2
2.2.12.03. Rho GDP-dissociation inhibitor 1, complex with G-protein RAC2 1hh4 Homo sapiens Eukaryo. plasma 2 0 3.6 ± 0.7 88 ± 6 -3.5
2.2.12.03. Rho GDP-dissociation inhibitor 1 1qvy Homo sapiens Eukaryo. plasma 1 0 3.1 ± 1.4 53 ± 15 -5.1
2.2.12.03. ADP-ribosylation factor-like protein 2, complex with human PDEdelta 1ksg Mus musculus Eukaryo. plasma 1 0 9.6 ± 2.0 41 ± 8 -5.3
2.2.12.03. Rho GDP-dissociation inhibitor 2, complex with G-protein RAC2 1ds6 Homo sapiens Eukaryo. plasma 2 0 2.8 ± 1.2 77 ± 9 -5.1
2.2.12.03. ADP-ribosylation factor 1 (ARF1) 2k5u Saccharomyces cerevisiae Golgi 1 0 2.8 ± 1.0 10 ± 10 -3.3
2.2.13.01. ADP-ribosylation factor binding protein Gga3 domain 1p4u Homo sapiens Golgi 1 0 10.7 ± 2.0 34 ± 16 -6.9
2.2.14.01. C2 domain of factor V 1czs Homo sapiens Eukaryo. plasma 1 0 4.2 ± 2.0 19 ± 20 -3.0
2.2.14.01. C2 domains of factor Va 1sdd Bos taurus Eukaryo. plasma 2 0 3.3 ± 2.0 40 ± 4 -5.6
2.2.14.01. C2 domain of factor VIII 1d7p Homo sapiens Eukaryo. plasma 1 0 3.9 ± 1.8 15 ± 11 -8.1
2.2.15.01. Ectodomain of G-protein coupled receptor Mth 1fjr Drosophila melanogaster Eukaryo. plasma 1 0 2.4 ± 1.0 60 ± 4 -3.4
2.2.16.01. Lipoprotein lppX 2byo Mycobacterium tuberculosis Bact. gram-pos plas. 1 0 1.6 ± 1.0 80 ± 7 -2.1
2.2.17.01. Follicle-stimulating hormone, complex of alpha and beta chains 1fl7 Homo sapiens Eukaryo. plasma 4 0 2.1 ± 1.6 75 ± 6 -3.6
2.2.17.01. Follicle-stimulating hormone-receptor complex 1xwd Homo sapiens Eukaryo. plasma 3 0 3.1 ± 1.9 53 ± 10 -5.0
2.2.18.01. Fusion glycoprotein E1 1rer Semiliki forest virus Viral 3 0 10.5 ± 1.0 61 ± 5 -5.1
2.2.18.01. Envelope glycoprotein 1urz Tick-borne encephalitis virus Viral 3 0 7.9 ± 1.0 7 ± 10 -12.2
2.2.18.01. Major envelope glycoprotein E, ectodomain 1ok8 Dengue virus Viral 3 0 4.9 ± 1.5 0 ± 5 -9.9
2.2.19.01. Adsorption protein p2 1n7v Bacteriophage prd1 Viral 1 0 15.7 ± 1.0 82 ± 7 -11.9
2.2.20.01. Spectrin beta chain 1btn Mus musculus Eukaryo. plasma 1 0 0.5 ± 1.4 57 ± 17 -1.2
2.2.20.01. Rac-beta serine/threonine protein kinase 1p6s Homo sapiens Eukaryo. plasma 1 0 4.4 ± 1.1 88 ± 15 -2.3
2.2.20.01. PH domain of tyrosine-protein kinase BTK 1bwn Homo sapiens Eukaryo. plasma 2 0 3.0 ± 0.5 89 ± 10 -2.0
2.2.20.01. PH domain of Src-associated adaptor protein 2 homologue 1u5f Mus musculus Eukaryo. plasma 2 0 2.2 ± 1.1 90 ± 11 -4.7
2.2.20.01. Cytohesin-3 (Grp1) 1fhx Mus musculus Eukaryo. plasma 1 0 3.1 ± 0.8 82 ± 11 -3.2
2.2.20.01. PH domain of phospholipase C delta 1 1mai Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 1.6 65 ± 19 -3.2
2.2.20.01. SET binding factor 1 1v5u Mus musculus Eukaryo. plasma 1 0 4.6 ± 1.6 56 ± 18 -4.1
2.2.20.01. PH domain of Src-associated adaptor protein 2 1u5e Mus musculus Eukaryo. plasma 2 0 4.0 ± 3.0 20 ± 15 -3.3
2.2.20.01. Dynamin 1dyn Homo sapiens Eukaryo. plasma 2 0 4.3 ± 0.9 30 ± 5 -11.2
2.2.20.01. Triple functional domain protein 1nty Homo sapiens Eukaryo. plasma 1 0 3.1 ± 1.8 60 ± 19 -3.7
2.2.20.01. Son of sevenless homolog 1 (SOS-1) 1xd4 Homo sapiens Eukaryo. plasma 1 0 3.2 ± 3.0 68 ± 13 -4.6
2.2.20.01. Pleckstrin 1pls Homo sapiens Eukaryo. plasma 1 0 3.2 ± 2.0 59 ± 20 -2.8
2.2.20.01. Phosphoinositol 3-phosphate binding protein 1 1upq Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.8 57 ± 20 -2.2
2.2.20.01. PH domain containing retinal protein 1 2d9v Mus musculus Eukaryo. plasma 1 0 3.0 ± 1.7 57 ± 11 -2.8
2.2.20.01. T-lymphoma invasion and metastasis-inducing protein 1, with G-protein RAC2 1foe Mus musculus Eukaryo. plasma 2 0 4.8 ± 1.8 46 ± 10 -6.2
2.2.20.01. PH domain of GPCR kinase 2 2bcj Bos taurus Eukaryo. plasma 3 0 3.3 ± 2.0 83 ± 2 -5.5
2.2.20.01. PH domain of docking protein 2 2d9w Homo sapiens Eukaryo. plasma 1 0 1.2 ± 1.2 19 ± 15 -1.3
2.2.20.01. Dual adaptor of phosphotyrosine and 3-phosphoinositides 1fao Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.7 54 ± 18 -3.9
2.2.20.01. Son of sevenless homolog 1 (two domains) 1dbh Homo sapiens Eukaryo. plasma 1 0 3.2 ± 2.0 29 ± 12 -5.0
2.2.20.01. PH domain of 3-phosphoinositide-dependent protein kinase 1 1w1g Homo sapiens Eukaryo. plasma 1 0 3.6 ± 1.9 31 ± 15 -4.2
2.2.20.01. PH domain of oxysterol binding protein-related protein 11 2d9x Homo sapiens Eukaryo. plasma 1 0 1.8 ± 1.8 51 ± 17 -2.3
2.2.20.01. PH domain of TAPP1 1eaz Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.7 77 ± 18 -2.1
2.2.20.01. PH domain of TAPP2 1v5p Mus musculus Eukaryo. plasma 1 0 2.6 ± 1.4 85 ± 15 -2.7
2.2.20.01. PH domain of muscle M-line assembly protein unc-89 1fho Caenorhabditis elegans Eukaryo. plasma 1 0 2.0 ± 1.7 12 ± 19 -2.3
2.2.20.01. Rac-alpha serine/threonine kinase 1unq Homo sapiens Eukaryo. plasma 1 0 1.6 ± 1.5 30 ± 20 -2.0
2.2.20.01. PH domain of Src-associated adaptor 55 protein 1u5d Homo sapiens Eukaryo. plasma 2 0 2.0 ± 1.7 12 ± 19 -2.3
2.2.20.02. Disabled homolog 1 1nu2 Mus musculus Eukaryo. plasma 1 0 0.5 ± 2.0 49 ± 20 -0.6
2.2.20.03. Radixin 1gc6 Mus musculus Eukaryo. plasma 1 0 1.1 ± 1.4 26 ± 11 -1.7
2.2.21.01. Hisactophilin-1 1hce Dictyostelium discoideum Eukaryo. plasma 1 0 1.9 ± 1.9 85 ± 20 -1.2
2.2.22.01. Hydrophobin I 2gvm Hypocrea jecorina Secreted<