PDB ID or protein name

All proteins in OPM (3404 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
1.1.02.03. Photosystem II 4pj0 Thermosynechococcus elongatus Thylakoid 34 72 30.8 ± 0.6 0 ± 0 -471.8
1.1.02.02. Photosystem I of cyanobacteria, complete trimeric complex 3pcq Thermosynechococcus elongatus Thylakoid 27 96 29.8 ± 0.8 0 ± 0 -429.6
1.1.02.03. Photosystem II 4yuu Cyanidium caldarium Thylakoid 34 70 32.2 ± 0.8 0 ± 0 -411.9
1.1.02.03. Photosystem II 3wu2 Thermosynechococcus vulcanus Thylakoid 32 70 32.4 ± 0.5 0 ± 0 -409.1
1.1.02.03. Photosystem II, Br-substituted 3a0b Thermosynechococcus vulcanus Thylakoid 34 72 31.8 ± 0.4 0 ± 0 -397.1
1.1.02.03. PSII-LHCII supercomplex 3jcu Spinacia oleracea Thylakoid 42 100 30.8 ± 0.0 0 ± 0 -385.6
1.1.02.02. Photosystem I of plants 4rku Pisum sativum Thylakoid 13 45 31.8 ± 1.0 1 ± 0 -346.8
1.2.01.01. Vascular endothelial growth factor receptor 2 (759-795), homotrimer 2met Homo sapiens Eukaryo. plasma 3 3 31.8 ± 1.5 1 ± 1 -331.1
1.1.02.02. Photosystem I of plants 4xk8 Arabidopsis thaliana Thylakoid 13 45 29.8 ± 0.5 0 ± 0 -319.6
1.1.13.02. ATP-sensitive K+ channel SUR1/Kir6.2 5twv Rattus norvegicus Eukaryo. plasma 8 76 31.8 ± 0.4 0 ± 0 -311.7
1.1.04.01. Respiratory complex I 2ybb Bos taurus Mitochon. inner 26 115 30.0 ± 0.3 9 ± 0 -310.3
1.1.02.03. Photosystem II, monomeric form 3kzi Thermosynechococcus elongatus Thylakoid 16 36 31.8 ± 0.5 0 ± 0 -310.1
1.1.04.01. Respiratory supercomplex I1III2IV1 5gup Sus scrofa Mitochon. inner 67 0 25.8 ± 1.8 9 ± 0 -304.0
1.1.04.01. Respiratory complex I 4hea Thermus thermophilus Bact. Gram-neg inner 7 67 29.8 ± 0.5 10 ± 0 -299.7
1.1.12.01. High conductance calcium-activated potassium channel, structure 2 5tji Aplysia californica Eukaryo. plasma 4 28 31.4 ± 0.6 0 ± 0 -294.2
1.1.12.10. ATP-sensitive K+ channel SUR1/Kir6.2 5wua Mus musculus Eukaryo. plasma 8 76 31.0 ± 0.6 0 ± 0 -286.4
1.1.02.02. Photosystem I of cyanobacteria 1jb0 Thermosynechococcus elongatus Thylakoid 9 32 31.4 ± 0.4 1 ± 0 -285.7
1.1.12.01. High conductance calcium-activated potassium channel, structure 1 5tj6 Aplysia californica Eukaryo. plasma 4 28 31.8 ± 0.6 0 ± 0 -273.6
1.1.12.01. K+ channel Eag1 (Kcnh1), with calmodulin 5k7l Rattus norvegicus Eukaryo. plasma 4 24 33.8 ± 0.6 0 ± 0 -272.0
1.1.02.02. Photosystem I of cyanobacteria, virus-like, structure 2 4l6v Synechocystis sp. Thylakoid 7 32 31.8 ± 0.2 2 ± 0 -269.6
1.1.12.01. Potassium channel Kv1.2. - Kv2.1. chimera 3lnm Rattus norvegicus Eukaryo. plasma 4 28 31.1 ± 0.9 0 ± 0 -260.7
1.3.32.01. Type II secretion system protein D 5wq7 Escherichia coli Bact. Gram-neg outer 15 60 23.8 ± 0.6 0 ± 0 -257.6
1.1.02.04. LH1-RC complex, C2 form 3wmm Thermochromatium tepidum Bact. Gram-neg inner 35 43 35.8 ± 0.0 1 ± 0 -254.6
1.1.12.01. Potassium channel Kv1.2 - Kv2.1. chimera, in membrane-like environment 2r9r Rattus norvegicus Eukaryo. plasma 4 28 30.8 ± 0.6 0 ± 0 -252.0
1.1.12.01. Na-activated potassium channel Slo2.2, open 5u70 Gallus gallus Eukaryo. plasma 4 24 31.4 ± 0.2 0 ± 0 -248.5
1.1.12.01. Potassium channel Kv1.2. - Kv2.1. chimera, complex with Charybdotoxin 4jtc Rattus norvegicus Eukaryo. plasma 4 24 30.2 ± 0.4 0 ± 0 -247.3
1.1.12.04. TRPV6 channel 5iwk Rattus norvegicus Eukaryo. plasma 4 24 30.4 ± 0.6 0 ± 0 -244.6
1.1.12.01. Nucleotide-gated channel 1, HCN1, structure 1 5u6o Homo sapiens Eukaryo. plasma 4 24 33.0 ± 0.8 0 ± 0 -238.4
1.1.04.01. Respiratory Complex I, class 3 5ldx Bos taurus Mitochon. inner 21 79 30.8 ± 0.0 6 ± 0 -237.1
1.1.12.01. Nucleotide-gated channel 1, HCN1, structure 2 5u6p Homo sapiens Eukaryo. plasma 4 26 31.8 ± 0.8 0 ± 0 -237.0
1.1.04.01. Respiratory complex I 3rko Escherichia coli Bact. Gram-neg inner 6 58 29.6 ± 0.0 9 ± 0 -236.7
1.1.12.01. Voltage-gated sodium channel Nav1.7- NavAb, with antagonist 5ek0 Arcobacter butzleri Bact. Gram-neg inner 4 24 30.2 ± 0.6 0 ± 0 -236.2
1.1.02.02. Photosystem I of cyanobacteria, virus-like, structure 1 4kt0 Synechocystis sp. Thylakoid 6 27 32.0 ± 0.7 0 ± 0 -235.3
1.1.02.04. LH1-RC complex, P21 form 3wmo Thermochromatium tepidum Bact. Gram-neg inner 35 43 31.8 ± 0.1 0 ± 0 -234.8
1.1.20.02. Innexin-6 gap junction channel 5h1r Caenorhabditis elegans Eukaryo. plasma 8 40 30.6 ± 0.4 0 ± 0 -233.4
1.1.12.05. Polycystin-2 channel, structure 1 5k47 Homo sapiens Eukaryo. plasma 4 24 30.8 ± 0.0 0 ± 0 -231.6
1.3.32.01. Type II secretion system protein D 5wq8 Vibrio cholerae Bact. Gram-neg outer 15 60 19.4 ± 0.0 0 ± 0 -231.2
1.1.12.01. Voltage-gated sodium channel NavAb, structure 5 (open) 5vb8 Arcobacter butzleri Bact. Gram-neg inner 4 24 31.4 ± 0.8 0 ± 0 -229.5
1.1.12.01. Voltage-gated sodium channel NavAb, structure 4 (closed) 5vb2 Arcobacter butzleri Bact. Gram-neg inner 4 24 31.0 ± 0.8 0 ± 0 -228.1
1.1.06.01. Cytochrome b6f 1q90 Chlamydomonas reinhardtii Thylakoid 16 26 31.8 ± 1.0 0 ± 1 -226.4
1.1.12.01. Cyclic nucleotide-gated ion Channel 5v4s Leptospira licerasiae Bact. Gram-neg inner 4 24 31.0 ± 0.2 0 ± 0 -223.4
1.1.06.01. Cytochrome b6f, structure 1 2e74 Mastigocladus laminosus Thylakoid 16 26 31.2 ± 0.8 0 ± 0 -222.1
1.1.04.01. Respiratory Complex I, class 1 5ldw Bos taurus Mitochon. inner 21 80 31.2 ± 0.3 5 ± 0 -221.8
1.1.26.04. L-carnitine/gamma-butyrobetaine antiporter 4m8j Proteus mirabilis Bact. Gram-neg inner 3 36 29.8 ± 0.8 0 ± 0 -220.2
1.1.12.04. TRPV2 channel 5an8 Oryctolagus cuniculus Eukaryo. plasma 4 24 31.8 ± 0.4 0 ± 0 -220.1
1.1.06.01. Cytochrome b6f, structure 3 4h13 Mastigocladus laminosus Thylakoid 16 26 31.6 ± 0.6 0 ± 0 -219.6
1.1.26.04. L-carnitine/gamma-butyrobetaine antiporter CaiT, open inward-facing conformation 2wsw Proteus mirabilis Bact. Gram-neg inner 3 42 29.8 ± 0.5 0 ± 0 -218.9
1.1.12.01. Voltage-gated sodium channel NavAb, structure 3 5klb Arcobacter butzleri Bact. Gram-neg inner 4 24 30.8 ± 0.3 1 ± 0 -218.3
1.1.04.01. Respiratory complex I 5lnk Ovis aries Mitochon. inner 21 78 29.4 ± 0.0 6 ± 0 -218.2
1.1.28.01. Multidrug efflux transporter AcrB-AcrZ complex, structure 1 4c48 Escherichia coli Bact. Gram-neg inner 6 39 29.2 ± 0.8 0 ± 0 -217.3
1.1.12.01. Voltage-gated sodium channel Nav1.7- NavAb, structure 1 3rvy Arcobacter butzleri Bact. Gram-neg inner 4 24 29.6 ± 0.4 0 ± 0 -216.9
1.1.04.01. Respiratory Complex I, class 2 5lc5 Bos taurus Mitochon. inner 21 83 30.8 ± 0.5 8 ± 0 -216.6
1.1.12.01. Na-activated potassium channel Slo2.2, closed 5u76 Gallus gallus Eukaryo. plasma 4 24 31.0 ± 0.4 0 ± 0 -216.3
1.1.28.01. Multidrug efflux transporter AcrB-AcrZ complex, structure 2 5nc5 Escherichia coli Bact. Gram-neg inner 6 39 29.8 ± 0.6 1 ± 0 -215.8
1.1.06.01. Cytochrome b6f, structure 4 4pv1 Mastigocladus laminosus Thylakoid 16 26 31.8 ± 0.5 0 ± 0 -215.7
1.1.06.01. Cytochrome b6f 2zt9 Nostoc sp. Thylakoid 16 26 31.2 ± 1.0 0 ± 1 -214.2
1.1.28.01. Drug efflux protein MtrD 4mt1 Neisseria gonorrhoeae Bact. Gram-neg inner 3 36 29.0 ± 0.3 0 ± 0 -214.1
1.1.12.04. TRPV1 ion channel 3j5p Rattus norvegicus Eukaryo. plasma 4 24 28.4 ± 0.7 0 ± 0 -213.2
1.1.26.04. L-carnitine/gamma-butyrobetaine antiporter CaiT, open inward-facing conformation 2wsx Escherichia coli Bact. Gram-neg inner 3 42 28.6 ± 0.7 7 ± 0 -212.7
1.1.12.04. TRPV1, in lipid nanodisc 5irz Rattus norvegicus Eukaryo. plasma 4 24 30.4 ± 0.7 0 ± 0 -208.9
1.1.12.01. Voltage-gated sodium channel NavPaS 5x0m Periplaneta americana Eukaryo. plasma 1 24 29.4 ± 0.8 7 ± 0 -208.5
1.1.12.01. Bacterial cyclic nucleotide regulated ion channel 3beh Rhizobium loti Bact. Gram-neg inner 4 24 30.6 ± 0.8 0 ± 0 -205.7
1.1.50.01. Particulate methane monooxygenase, different structure 3rgb Methylococcus capsulatus Bact. Gram-neg inner 9 39 28.2 ± 0.6 0 ± 0 -204.9
1.1.07.01. Mitochondrial cytochrome c oxidase, with cytochrome c 5iy5 Bos taurus Mitochon. inner 20 56 25.8 ± 1.2 0 ± 0 -204.7
1.1.26.04. L-carnitine/gamma-butyrobetaine antiporter CaiT, substrate-bound 3hfx Escherichia coli Bact. Gram-neg inner 3 42 29.8 ± 0.8 0 ± 0 -203.5
1.1.12.04. TRPV1 ion channel, complex with DkTx and RTX toxins 3j5q Rattus norvegicus Eukaryo. plasma 4 24 30.0 ± 0.5 0 ± 0 -203.0
1.1.12.08. Ryanodine receptor 1, various structures 5gl0 Oryctolagus cuniculus Endoplasm. reticulum 4 24 30.8 ± 0.0 0 ± 0 -202.9
1.1.28.01. Multidrug efflux transporter AcrB, asymmetric, complex with ankyrin repeat 2 3nog Escherichia coli Bact. Gram-neg inner 3 36 29.0 ± 0.5 3 ± 0 -202.9
1.1.32.01. Proton glutamate symport protein, outward-facing state 1 2nwl Pyrococcus horikoshii Archaebac. 3 39 29.8 ± 1.3 0 ± 0 -202.1
1.1.64.01. Ca2+/H+ antiporter YfkE, different conformation 4kjs Bacillus subtilis Bact. Gram-pos plas. 3 33 31.2 ± 0.8 0 ± 0 -201.6
1.1.12.01. Voltage-gated sodium channel 4bgn Caldalkalibacillus thermarum Bact. Gram-pos plas. 4 24 27.0 ± 0.3 0 ± 0 -201.5
1.1.26.08. Band 3 anion transport protein, SLC4A1 4yzf Homo sapiens Eukaryo. plasma 2 28 31.8 ± 1.0 2 ± 0 -201.4
1.1.12.01. Voltage-gated sodium channel NavAb, structure 2 4ekw Arcobacter butzleri Bact. Gram-neg inner 4 24 29.4 ± 0.5 0 ± 0 -201.0
1.1.50.01. Particulate methane monooxygenase 4phz Methylocystis sp. Bact. Gram-neg inner 12 42 30.0 ± 0.9 0 ± 0 -200.6
1.1.32.01. Proton glutamate symport protein, outward-facing state 2 2nww Pyrococcus horikoshii Archaebac. 3 36 30.6 ± 0.6 0 ± 0 -200.2
1.1.26.04. Glycine betaine transporter BetP, asymmetric trimer, conformation 1 4ain Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 29.8 ± 0.6 0 ± 0 -198.8
1.1.26.04. Glycine betaine transporter BetP, substrate-bound 2wit Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 30.4 ± 1.2 0 ± 0 -198.6
1.1.07.01. Mitochondrial cytochrome c oxidase 2dyr Bos taurus Mitochon. inner 20 56 28.0 ± 0.6 0 ± 0 -198.1
1.1.32.01. Proton/glutamate symporter, substrate-bound 5e9s Pyrococcus kodakaraensis Archaebac. 3 24 31.4 ± 0.6 0 ± 0 -197.9
1.1.06.01. Cytochrome bc1, mitochondrial, bovine/chicken, structure 1 1bcc Bos taurus Mitochon. inner 24 10 29.8 ± 0.6 0 ± 0 -197.0
1.1.06.01. Cytochrome bc1, bacterial, structure 2 5kkz Rhodobacter sphaeroides Bact. Gram-neg inner 5 19 32.0 ± 1.0 2 ± 0 -195.4
1.1.12.08. Ryanodine receptor 2, open state 5goa Sus scrofa Eukaryo. plasma 4 24 30.8 ± 0.1 0 ± 0 -194.3
1.1.02.05. Light-harvesting complex LH2 1nkz Rhodopseudomonas acidophila Bact. Gram-neg inner 18 18 31.8 ± 0.6 0 ± 0 -193.5
1.1.12.01. Bacterial cyclic nucleotide regulated ion channel, different conformation 2zd9 Rhizobium loti Bact. Gram-neg inner 4 24 31.6 ± 1.2 0 ± 0 -192.8
1.1.15.01. Glycine receptor, alpha-1, glycine-bound state 3jae Danio rerio Eukaryo. plasma 5 20 31.8 ± 0.4 0 ± 0 -191.1
1.1.12.04. TRPV1 with DkTx and RTX, in lipid nanodisc 5irx Rattus norvegicus Eukaryo. plasma 4 24 29.6 ± 0.5 0 ± 0 -190.8
1.1.15.02. Proton-gated ion channel, conformation 1 3tlw Gloeobacter violaceus Bact. Gram-neg inner 5 20 34.0 ± 1.6 0 ± 0 -190.3
1.1.12.08. Ryanodine receptor 1, closed structure 2 3j8h Oryctolagus cuniculus Endoplasm. reticulum 4 24 30.8 ± 0.0 0 ± 0 -190.3
1.1.76.01. Acid-activated urea channel 3ux4 Helicobacter pylori Bact. Gram-neg inner 6 36 30.0 ± 0.5 0 ± 0 -190.2
1.1.06.01. Cytochrome bc1, mitochondrial, bovine/chicken, structure 2 3bcc Bos taurus Mitochon. inner 24 10 28.6 ± 1.0 0 ± 0 -190.1
1.1.28.01. Multidrug efflux transporter AcrB, symmetric 3d9b Escherichia coli Bact. Gram-neg inner 3 36 28.4 ± 0.6 0 ± 0 -189.9
1.1.08.01. V-type Sodium ATPase 2bl2 Enterococcus hirae Bact. Gram-pos plas. 10 40 35.6 ± 0.7 0 ± 0 -189.6
1.1.66.01. Proton-translocating pyrophosphatase, structure 1 4a01 Vigna radiata (Mung bean) Vacuole 2 32 32.0 ± 0.8 0 ± 0 -189.3
1.1.12.08. Ryanodine receptor 1, closed structure 3 5gkz Oryctolagus cuniculus Endoplasm. reticulum 4 24 30.8 ± 0.0 0 ± 0 -188.8
1.1.06.01. Cytochrome bc1, bacterial 2yiu Paracoccus denitrificans Bact. Gram-neg inner 6 20 29.8 ± 0.5 0 ± 0 -188.8
1.1.06.01. Cytochrome bc1, bacterial, structure 1 2qjy Rhodobacter sphaeroides Bact. Gram-neg inner 6 20 30.2 ± 0.6 0 ± 0 -188.6
1.1.01.01. Proteorhodopsin 4jq6 Gamma-proteobacterium Bact. Gram-neg inner 6 42 28.4 ± 1.3 0 ± 0 -188.5
1.1.50.01. Particulate methane monooxygenase 1yew Methylococcus capsulatus Bact. Gram-neg inner 9 42 28.2 ± 0.7 0 ± 0 -188.5
1.1.14.02. Formate transporter 1, FocA 3kly Vibrio cholerae Bact. Gram-neg inner 5 35 31.4 ± 0.5 1 ± 0 -188.2
1.1.12.08. Ryanodine receptor 2, closed state 5go9 Sus scrofa Eukaryo. plasma 4 24 30.8 ± 0.3 0 ± 0 -188.1
1.1.12.06. Two pore calcium channel TPC1 5dqq Arabidopsis thaliana Vacuole 2 24 29.8 ± 0.5 0 ± 0 -188.0
1.1.12.01. Bacterial cyclic nucleotide regulated ion channel, full structure 4chw Rhizobium loti Bact. Gram-neg inner 4 24 29.8 ± 0.6 0 ± 0 -187.8
1.1.28.01. Multidrug efflux transporter AcrB, asymmetric 2gif Escherichia coli Bact. Gram-neg inner 3 36 29.0 ± 0.2 1 ± 0 -187.5
1.1.12.04. TRPV2 channel 5hi9 Rattus norvegicus Eukaryo. plasma 4 24 30.2 ± 1.0 0 ± 0 -187.5
1.1.15.02. Proton-gated ion channel, conformation 6 5heg Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.0 ± 0.8 0 ± 0 -186.8
1.1.26.04. Glycine betaine transporter BetP, inward-facing conformation 4c7r Corynebacterium glutamicum Bact. Gram-pos plas. 3 39 30.0 ± 0.7 1 ± 0 -186.7
1.1.06.01. Cytochrome bc1, mitochondrial, structure 1 1l0l Bos taurus Mitochon. inner 12 26 30.0 ± 0.6 0 ± 0 -186.6
1.1.26.04. Glycine betaine transporter BetP, asymmetric trimer, conformation 2 4doj Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 30.0 ± 0.6 0 ± 0 -186.4
1.1.32.01. Proton glutamate symport protein, outward-facing state 3 5cfy Pyrococcus horikoshii Archaebac. 3 33 29.8 ± 0.3 0 ± 0 -185.9
1.1.12.09. Voltage-dependent calcium channel, structure 3 5gjw Oryctolagus cuniculus Eukaryo. plasma 2 28 31.6 ± 0.6 2 ± 0 -185.6
1.1.66.01. K(+)-pumping pyrophosphatase, structure 3 5lzq Thermotoga maritima Bact. Gram-neg inner 2 32 31.0 ± 0.6 0 ± 0 -185.6
1.1.15.02. Proton-gated ion channel, resting state 4npq Gloeobacter violaceus Bact. Gram-neg inner 5 20 33.8 ± 2.1 1 ± 0 -185.4
1.1.06.01. Cytochrome bc1, mitochondrial 3h1j Gallus gallus Mitochon. inner 10 24 28.2 ± 0.6 0 ± 0 -184.8
1.1.15.02. Proton-gated ion channel, conformation 7 5hcm Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.0 ± 1.4 0 ± 0 -184.3
1.1.12.09. Voltage-dependent calcium channel, structure 2 5gjv Oryctolagus cuniculus Eukaryo. plasma 2 28 32.0 ± 0.8 5 ± 0 -184.3
1.1.32.01. Proton/glutamate symporter, apo 5dwy Pyrococcus kodakaraensis Archaebac. 3 24 30.8 ± 0.6 0 ± 0 -184.1
1.1.26.03. Sodium/sugar symporter vSGLT, substrate-bound 3dh4 Vibrio parahaemolyticus Bact. Gram-neg inner 2 30 30.0 ± 0.7 0 ± 0 -184.0
1.1.05.05. Succinate dehydrogenase 1nek Escherichia coli Bact. Gram-neg inner 6 18 32.0 ± 0.6 0 ± 0 -183.5
1.1.15.02. Proton-gated ion channel, open state 3eam Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.7 ± 0.9 0 ± 1 -183.4
1.1.15.02. Proton-gated ion channel, conformation 5 5heh Gloeobacter violaceus Bact. Gram-neg inner 5 20 33.4 ± 1.0 0 ± 0 -183.3
1.1.06.01. Cytochrome bc1, mitochondrial, structure 2 2fyu Bos taurus Mitochon. inner 12 26 29.8 ± 0.5 0 ± 0 -182.9
1.1.66.01. K(+)-pumping pyrophosphatase, structure 1 4av3 Thermotoga maritima Bact. Gram-neg inner 2 32 29.8 ± 0.7 0 ± 0 -182.5
1.1.64.01. Ca2+/H+ antiporter YfkE 4kjr Bacillus subtilis Bact. Gram-pos plas. 3 33 29.8 ± 0.4 0 ± 0 -181.6
1.1.28.01. Multidrug efflux transporter AcrB, asymmetric, complex with ankyrin repeat 1 4dx5 Escherichia coli Bact. Gram-neg inner 3 36 27.4 ± 0.7 1 ± 0 -181.0
1.1.08.01. V-type proton ATPase, vacuolar, state 2 3j9u Saccharomyces cerevisiae Vacuole 10 40 40.4 ± 1.1 0 ± 0 -180.4
1.1.15.01. Glycine receptor, alpha-1, glycine/ivermectin-bound state 3jaf Danio rerio Eukaryo. plasma 5 20 33.4 ± 1.4 0 ± 0 -180.2
1.1.06.01. Cytochrome bc1, bacterial, structure 3 5kli Rhodobacter sphaeroides Bact. Gram-neg inner 6 20 29.8 ± 1.6 0 ± 0 -180.0
1.1.06.01. Cytochrome bc1, mitochondrial, structure 3 1pp9 Bos taurus Mitochon. inner 10 24 29.8 ± 0.4 2 ± 0 -179.7
1.1.15.02. Proton-gated ion channel, conformation 3 4lml Gloeobacter violaceus Bact. Gram-neg inner 5 20 31.8 ± 0.7 0 ± 0 -178.8
1.1.06.01. Cytochrome bc1, bacterial 1zrt Rhodobacter capsulatus Bact. Gram-neg inner 6 20 29.9 ± 0.9 0 ± 0 -178.6
1.1.08.01. V-type proton ATPase, vacuolar, state 3 3j9v Saccharomyces cerevisiae Vacuole 10 40 40.0 ± 1.2 0 ± 0 -178.0
1.1.15.02. Proton-gated ion channel, conformation 2 4lmj Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.4 ± 0.7 0 ± 0 -177.4
1.1.26.08. Boron transporter 1 5sv9 Saccharomyces mikatae Eukaryo. plasma 2 28 33.6 ± 0.6 1 ± 0 -177.0
1.1.66.01. Proton-translocating pyrophosphatase, structure 2 5gpj Vigna radiata (Mung bean) Vacuole 2 32 31.0 ± 0.4 0 ± 0 -176.0
1.1.26.04. Glycine betaine transporter BetP, outward-open 4llh Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 29.8 ± 0.4 0 ± 0 -175.4
1.1.15.02. Proton-gated ion channel, conformation 8 5l4h Gloeobacter violaceus Bact. Gram-neg inner 5 20 31.8 ± 1.4 0 ± 1 -175.1
1.1.20.01. Connexin 26 gap junction channel, structure 2 5er7 Homo sapiens Eukaryo. plasma 6 24 31.4 ± 0.7 0 ± 0 -174.7
1.1.02.05. Light-harvesting complex LH3 1ijd Rhodopseudomonas acidophila Bact. Gram-neg inner 18 18 29.8 ± 0.7 0 ± 0 -174.6
1.1.17.01. Rhesus Glycoprotein RhCG 3hd6 Homo sapiens Eukaryo. plasma 3 36 31.8 ± 0.7 0 ± 0 -174.1
1.1.12.08. Ryanodine receptor 1, closed structure 1 5gky Oryctolagus cuniculus Endoplasm. reticulum 4 24 30.8 ± 0.0 1 ± 0 -174.0
1.1.06.01. Cytochrome bc1, mitochondrial, with cytochrome c iso-1 3cx5 Saccharomyces cerevisiae Mitochon. inner 10 24 27.2 ± 0.6 0 ± 0 -173.9
1.1.07.01. Bacterial cytochrome c oxidase 1m56 Rhodobacter sphaeroides Bact. Gram-neg inner 4 22 29.6 ± 1.8 3 ± 0 -173.7
1.1.66.01. K(+)-pumping pyrophosphatase, structure 2 4av6 Thermotoga maritima Bact. Gram-neg inner 2 32 29.8 ± 0.8 0 ± 0 -173.1
1.1.32.01. Proton glutamate symport protein, inward-facing state 2 4p19 Pyrococcus horikoshii Archaebac. 3 30 30.6 ± 1.0 0 ± 0 -172.9
1.1.57.02. Intramembrane aspartate protease 4hyg Methanoculleus marisnigri Archaebac. 3 27 31.8 ± 0.3 0 ± 0 -172.7
1.1.15.02. Proton-gated ion channel, conformation 9 5j0z Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.2 ± 1.4 0 ± 0 -171.9
1.1.19.01. Mechanosensitive channel protein MscS, expanded state 2oau Escherichia coli Bact. Gram-neg inner 7 14 31.8 ± 0.8 1 ± 1 -171.3
1.1.06.01. Cytochrome bc1, mitochondrial 1ezv Saccharomyces cerevisiae Mitochon. inner 24 10 27.5 ± 0.6 1 ± 0 -170.6
1.1.01.01. Sodium pumping rhodopsin, NaR, pentamer 4xto Dokdonia eikasta Bact. Gram-neg inner 5 35 29.8 ± 0.5 0 ± 0 -170.3
1.1.32.01. Proton glutamate symport protein, mixed inward/outward trimer 3v8g Pyrococcus horikoshii Archaebac. 3 30 29.8 ± 1.0 5 ± 0 -169.4
1.1.08.01. V-type proton ATPase, vacuolar, state 1 3j9t Saccharomyces cerevisiae Vacuole 10 40 39.6 ± 1.3 1 ± 0 -169.3
1.1.12.05. Polycystin-2 channel, structure 2 5mke Homo sapiens Eukaryo. plasma 4 24 25.8 ± 0.0 1 ± 0 -168.9
1.1.32.01. Proton glutamate symport protein, outward-facing state 4 4oye Pyrococcus horikoshii Archaebac. 3 30 28.2 ± 0.6 0 ± 0 -168.8
1.1.65.01. Concentrative nucleoside transporter, inward-facing state 5l26 Neisseria wadsworthii Bact. Gram-neg inner 3 24 29.0 ± 0.4 0 ± 0 -168.2
1.1.07.01. Bacterial cytochrome c oxidase 1qle Paracoccus denitrificans Bact. Gram-neg inner 4 22 31.7 ± 1.3 4 ± 0 -167.4
1.1.28.01. Multidrug exporter MexB 2v50 Pseudomonas aeruginosa Bact. Gram-neg inner 3 36 28.6 ± 1.0 0 ± 1 -167.3
1.1.06.01. Cytochrome bc1, mitochondrial, with cytochrome c iso-2 3cxh Saccharomyces cerevisiae Mitochon. inner 24 10 27.6 ± 1.1 0 ± 0 -167.0
1.1.65.01. Concentrative nucleoside transporter, intermediate 1 state 5l27 Neisseria wadsworthii Bact. Gram-neg inner 3 24 27.8 ± 1.2 2 ± 0 -166.9
1.1.28.02. Efflux transporter CusA, apo-protein 3k07 Escherichia coli Bact. Gram-neg inner 3 33 27.4 ± 1.2 0 ± 0 -166.7
1.1.12.03. TrkH/TrkA potassium transport complex, structure 1 4j7c Bacillus subtilis Bact. Gram-pos plas. 2 16 31.8 ± 1.0 0 ± 0 -165.6
1.1.28.02. Efflux transporter CusA, complex with CusB 3ne5 Escherichia coli Bact. Gram-neg inner 3 36 29.0 ± 0.7 0 ± 0 -165.0
1.1.65.01. Concentrative nucleoside transporter, outward-facing state 5l2a Neisseria wadsworthii Bact. Gram-neg inner 3 24 27.8 ± 0.6 0 ± 0 -164.7
1.1.12.03. Potassium uptake protein TrkH 3pjz Vibrio parahaemolyticus Bact. Gram-neg inner 2 20 29.7 ± 0.6 1 ± 0 -164.0
1.1.12.05. Polycystin-2 channel, structure 3 5mkf Homo sapiens Eukaryo. plasma 4 24 29.0 ± 1.2 0 ± 1 -164.0
1.1.65.01. Concentrative nucleoside transporter, intermediate 2 state 5l24 Neisseria wadsworthii Bact. Gram-neg inner 3 24 26.6 ± 1.2 5 ± 0 -163.9
1.1.02.05. Light-harvesting complex 1lgh Rhodospirillum molischianum Bact. Gram-neg inner 16 16 29.7 ± 0.5 0 ± 0 -163.4
1.1.26.03. Sodium/sugar symporter vSGLT, substrate-free 2xq2 Vibrio parahaemolyticus Bact. Gram-neg inner 2 30 30.4 ± 0.6 0 ± 0 -162.7
1.1.15.02. Proton-gated ion channel, Glic/Elic chimera 4yeu Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.6 ± 1.1 0 ± 0 -162.5
1.1.88.01. NAD(P) transhydrogenase, structure 1 4o9p Thermus thermophilus Bact. Gram-neg inner 4 24 29.8 ± 0.9 0 ± 0 -162.0
1.1.43.01. Saccharide transporter, EIIC (ChbC), outward-facing 5iws Bacillus cereus Bact. Gram-pos plas. 2 20 31.2 ± 1.0 0 ± 0 -161.7
1.1.28.01. Heavy metal cation tricomponent efflux pump, ZneA 4k0e Ralstonia metallidurans Bact. Gram-neg inner 3 36 28.0 ± 0.7 0 ± 0 -161.5
1.1.14.02. Formate/nitrite transporter 3tdp Clostridium difficile Bact. Gram-pos plas. 5 30 28.4 ± 1.9 0 ± 0 -161.3
1.1.14.02. Formate transporter 1, FocA 3kcu Escherichia coli Bact. Gram-neg inner 5 35 29.9 ± 0.7 0 ± 0 -160.9
1.1.26.04. Glycine betaine transporter BetP, alternative inward-facing open conformation 3p03 Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 29.8 ± 0.7 1 ± 0 -160.9
1.1.26.01. Leucine transporter LeuT, outward-facing substrate-free conformation 3tt1 Aquifex aeolicus Bact. Gram-neg inner 2 24 28.2 ± 1.2 0 ± 0 -160.8
1.1.12.01. Sodium channel NavMs, full-length 5hvx Magnetococcus marinus Bact. Gram-neg inner 4 24 29.0 ± 0.6 0 ± 0 -159.6
1.1.01.01. Blue-light absorbing proteorhodopsin 4knf Gamma-proteobacterium Bact. Gram-neg inner 5 35 28.4 ± 1.5 1 ± 1 -159.6
1.1.32.01. Proton glutamate symport protein, inward-facing state 1 3kbc Pyrococcus horikoshii Archaebac. 3 30 28.1 ± 0.9 0 ± 1 -158.8
1.1.26.05. Arginine/agmatine transporter (AdiC), intermediate conformation 3ob6 Escherichia coli Bact. Gram-neg inner 2 24 29.8 ± 1.4 3 ± 1 -158.7
1.1.15.01. Gamma-aminobutyric acid receptor, GABA 4cof Homo sapiens Eukaryo. plasma 5 20 31.6 ± 0.6 0 ± 0 -158.5
1.1.26.01. Leucine transporter LeuT, outward-facing substrate-bound conformation 2a65 Aquifex aeolicus Bact. Gram-neg inner 2 28 29.8 ± 0.5 0 ± 0 -157.9
1.1.08.01. V-type proton ATPase, vacuolar 5tj5 Saccharomyces cerevisiae Vacuole 13 54 35.8 ± 0.2 2 ± 0 -157.9
1.1.31.01. Tellurite resistance protein tehA homolog 3m73 Haemophilus influenzae Bact. Gram-neg inner 3 30 29.1 ± 1.4 0 ± 0 -157.4
1.1.17.01. Ammonium transporter MEP2, structure 2 5ah3 Candida albicans Eukaryo. plasma 3 33 31.8 ± 0.7 0 ± 0 -157.0
1.1.06.01. Cytochrome b6f, structure 2 2d2c Mastigocladus laminosus Thylakoid 16 26 28.6 ± 0.6 0 ± 0 -156.9
1.1.28.01. Multidrug efflux transporter AcrB with YajC subunit , symmetric 2rdd Escherichia coli Bact. Gram-neg inner 6 39 28.4 ± 0.5 0 ± 0 -156.2
1.1.20.01. Connexin 26 gap junction channel, structure 1 2zw3 Homo sapiens Eukaryo. plasma 6 24 32.2 ± 0.5 0 ± 0 -155.9
1.1.72.02. YdaH transporter 4r0c Alcanivorax borkumensis Bact. Gram-neg inner 2 22 29.8 ± 0.5 0 ± 0 -155.5
1.1.57.03. Gamma-secretase complex, structure 4 5fn3 Homo sapiens Endoplasm. reticulum 5 19 30.6 ± 0.9 4 ± 0 -155.5
1.1.65.01. Concentrative nucleoside transporter, intermediate 3 state 5u9w Neisseria wadsworthii Bact. Gram-neg inner 3 24 29.0 ± 0.2 2 ± 0 -155.3
1.1.65.01. Concentrative nucleoside transporter 3tij Vibrio cholerae Bact. Gram-neg inner 3 27 27.0 ± 0.5 0 ± 0 -155.2
1.1.26.05. Arginine/agmatine antiporter (AdiC), outward-facing structure 2 5j4i Escherichia coli Bact. Gram-neg inner 2 24 32.8 ± 0.9 0 ± 0 -155.1
1.1.35.02. Na+/H+ antiporter 1, outward-open conformation 4d0a Methanococcus jannaschii Archaebac. 2 26 28.4 ± 1.0 0 ± 0 -155.0
1.1.35.01. Sodium/proton antiporter 1 (NhaA), dimer, different conformation 4atv Escherichia coli Bact. Gram-neg inner 2 24 28.6 ± 1.3 1 ± 0 -154.7
1.1.17.01. Ammonium transporter MEP2, structure 1 5aez Candida albicans Eukaryo. plasma 3 33 32.4 ± 0.8 0 ± 0 -154.4
1.1.14.01. Aquaporin TIP2-1 5i32 Arabidopsis thaliana Vacuole 4 24 30.0 ± 0.8 0 ± 0 -154.0
1.1.02.06. Light-Harvesting Complex II 1rwt Spinacia oleracea Thylakoid 3 9 30.0 ± 0.7 0 ± 0 -154.0
1.1.15.01. 5-hydroxytryptamine receptor 3A 4pir Mus musculus Eukaryo. plasma 5 20 30.8 ± 1.0 0 ± 0 -153.9
1.1.28.02. Efflux transporter CusA, complex with CusB, pre-extrusion state 3t56 Escherichia coli Bact. Gram-neg inner 3 36 30.4 ± 0.6 0 ± 0 -153.7
1.1.12.01. Potassium channel Kv1.2., full-length 3lut Rattus norvegicus Eukaryo. plasma 4 24 25.1 ± 0.5 0 ± 0 -153.1
1.1.17.01. Ammonium transporter Amt-1 2b2f Archaeoglobus fulgidus Archaebac. 3 33 28.9 ± 0.7 0 ± 0 -152.5
1.1.14.01. Aquaporin-1, structure 2 4csk Homo sapiens Eukaryo. plasma 4 24 31.6 ± 0.8 0 ± 0 -152.1
1.1.50.01. Particulate methane monooxygenase 3chx Methylosinus trichosporium Bact. Gram-neg inner 10 30 29.8 ± 0.4 0 ± 0 -152.0
1.1.12.03. TrkH/TrkA potassium transport complex 4j9u Vibrio parahaemolyticus Bact. Gram-neg inner 2 20 29.4 ± 0.7 0 ± 0 -151.9
1.1.88.01. NAD(P) transhydrogenase, structure 2 4o9u Thermus thermophilus Bact. Gram-neg inner 4 24 30.6 ± 1.1 1 ± 0 -150.7
1.1.17.01. Rh-like protein 3b9y Nitrosomonas europaea Bact. Gram-neg inner 3 33 29.8 ± 1.3 0 ± 0 -150.1
1.1.08.01. F1F0 ATP synthase, F0 complex 1c17 Escherichia coli Bact. Gram-neg inner 13 28 34.6 ± 1.2 4 ± 0 -149.9
1.1.12.01. Na(v)Rh voltage-gated sodium channel 4dxw Alpha proteobacterium Bact. Gram-neg inner 4 24 29.2 ± 0.7 4 ± 0 -149.7
1.1.80.01. Phospho-N-acetylmuramoyl-pentapeptide-transferase, structure 2 5ckr Aquifex aeolicus Bact. Gram-neg inner 2 20 30.4 ± 1.1 0 ± 0 -149.3
1.1.14.02. Formate transporter 3q7k Salmonella enterica Bact. Gram-neg inner 5 30 28.6 ± 0.0 0 ± 0 -148.8
1.1.17.01. Ammonia Channel 1u7g Escherichia coli Bact. Gram-neg inner 3 33 29.8 ± 1.3 0 ± 0 -148.7
1.1.17.01. Ammonia channel, complex with inhibitory GlnK 2ns1 Escherichia coli Bact. Gram-neg inner 3 33 29.1 ± 0.7 0 ± 0 -148.7
1.1.22.01. Pore-forming haemolysin E (ClyA) 2wcd Escherichia coli Secreted 12 36 30.8 ± 0.7 0 ± 0 -148.3
1.1.14.01. Glycerol uptake facilitator 1ldf Escherichia coli Bact. Gram-neg inner 4 32 30.1 ± 0.9 0 ± 0 -147.9
1.1.28.02. Efflux transporter CusA, Cu(i) complex 3kss Escherichia coli Bact. Gram-neg inner 3 33 28.8 ± 0.5 0 ± 0 -147.7
1.1.12.01. Potassium channel Kv1.2. 2a79 Rattus norvegicus Eukaryo. plasma 4 28 29.8 ± 1.5 0 ± 0 -147.0
1.1.01.02. Opioid kappa receptor 4djh Homo sapiens Eukaryo. plasma 2 14 32.0 ± 0.8 1 ± 0 -146.6
1.1.07.01. Bacterial cytochrome c oxidase, caa3-type 2yev Thermus thermophilus Bact. Gram-neg inner 3 21 31.2 ± 0.8 6 ± 0 -146.1
1.1.01.02. Adenosine receptor A1 5uen Homo sapiens Eukaryo. plasma 2 14 32.2 ± 1.0 1 ± 0 -145.8
1.3.32.01. Type III secretion injectisome secretin InvG 5tcq Salmonella enterica Bact. Gram-neg outer 15 0 17.0 ± 0.4 90 ± 0 -145.8
1.1.57.03. Gamma-secretase complex, structure 3 5fn2 Homo sapiens Endoplasm. reticulum 4 18 31.4 ± 0.9 6 ± 0 -145.5
1.1.12.02. G protein-activated inward rectifier potassium channel 2 (GIRK2, Kir3.2) 3sya Mus musculus Eukaryo. plasma 4 8 34.8 ± 0.7 0 ± 0 -145.5
1.1.01.02. Beta-1 adrenergic receptor, inactive, dimer 4gpo Meleagris gallopavo Eukaryo. plasma 2 14 30.8 ± 1.2 0 ± 0 -144.8
1.3.20.01. Fe-regulated protein B 4aip Neisseria meningitidis Bact. Gram-neg outer 3 66 23.4 ± 0.3 0 ± 0 -144.6
1.1.26.01. Leucine transporter LeuT, outward-facing conformation, from bicelles 4fxz Aquifex aeolicus Bact. Gram-neg inner 2 24 28.0 ± 0.6 0 ± 0 -144.3
1.1.15.01. Glycine receptor, alpha-3, structure 1 5cfb Homo sapiens Eukaryo. plasma 5 20 33.8 ± 0.5 4 ± 2 -144.1
1.1.01.01. Archaerhodopsin-2, trimeric 2ei4 Halobacterium sp. Archaebac. 3 21 30.5 ± 1.2 0 ± 1 -143.9
1.1.12.03. TrkH/TrkA potassium transport complex, structure 2 5but Bacillus subtilis Bact. Gram-pos plas. 2 16 32.0 ± 0.7 0 ± 0 -143.8
1.1.14.01. Aquaporin AqpM 3ne2 Archaeoglobus fulgidus Archaebac. 4 24 31.2 ± 1.3 0 ± 0 -143.5
1.1.01.02. Squid rhodopsin, complex with 11-cis retinal, dimer 2z73 Todarodes pacificus Eukaryo. plasma 2 14 32.9 ± 1.0 0 ± 1 -143.3
1.1.14.01. Aquaporin-0 2b6o Ovis aries Eukaryo. plasma 4 32 31.8 ± 1.4 0 ± 0 -143.3
1.1.01.02. Beta-2 adrenergic receptor, inactive state, dimer 2rh1 Homo sapiens Eukaryo. plasma 2 14 31.8 ± 0.9 0 ± 1 -143.2
1.1.57.03. Gamma-secretase complex, structure 5 5fn4 Homo sapiens Endoplasm. reticulum 5 18 30.4 ± 0.9 7 ± 0 -143.1
1.1.26.01. Leucine transporter LeuT, outward-facing, return state 5jae Aquifex aeolicus Bact. Gram-neg inner 2 24 29.0 ± 0.8 0 ± 0 -143.0
1.1.18.01. Mechanosensitive channel MscL, closed state 2oar Mycobacterium tuberculosis Bact. Gram-pos plas. 5 10 36.1 ± 2.2 0 ± 0 -142.7
1.3.16.01. Osmoporin OMPC, isoform 1 2ixx Escherichia coli Bact. Gram-neg outer 3 48 26.2 ± 1.3 0 ± 1 -142.5
1.3.20.01. SusD-SusC complex, BT_2263, a dimer 5fq6 Bacteroides thetaiotaomicron Bact. Gram-neg inner 2 44 26.6 ± 2.2 0 ± 0 -142.4
1.1.05.02. Formate dehydrogenase 1kqf Escherichia coli Bact. Gram-neg inner 6 15 33.7 ± 1.1 0 ± 0 -141.9
1.1.80.01. Phospho-N-acetylmuramoyl-pentapeptide-transferase, structure 1 4j72 Aquifex aeolicus Bact. Gram-neg inner 2 20 31.4 ± 1.2 0 ± 0 -141.4
1.1.01.01. Halorhodopsin 3a7k Natronomonas pharaonis Archaebac. 3 21 33.8 ± 1.4 1 ± 0 -141.3
1.1.102.01. STRA6 receptor, with calmodulin 5sy1 Danio rerio Eukaryo. plasma 2 18 30.8 ± 0.0 0 ± 0 -141.2
1.1.94.01. Ascorbate-specific permease IIC component UlaA, structure 2 4rp9 Escherichia coli Bact. Gram-neg inner 2 22 29.8 ± 0.6 2 ± 0 -141.1
1.1.19.01. Mechanosensitive channel protein MscS, closed state 4hw9 Helicobacter pylori Bact. Gram-neg inner 7 14 31.6 ± 1.8 0 ± 0 -140.9
1.1.43.01. Saccharide transporter, EIIC (ChbC), inward-facing 3qnq Bacillus cereus Bact. Gram-pos plas. 2 20 29.6 ± 1.0 1 ± 0 -140.6
1.1.01.01. Halorhodopsin, different conformation 3vvk Natronomonas pharaonis Archaebac. 3 21 33.6 ± 1.1 0 ± 0 -140.5
1.1.36.01. ClC chloride transporter 3org Cyanidoschyzon merolae Eukaryo. plasma 2 28 28.7 ± 1.3 0 ± 2 -140.4
1.1.41.02. Bidirectional sugar transporter SWEET2b 5ctg Oryza sativa (Rice) Eukaryo. plasma 3 21 33.0 ± 1.2 2 ± 0 -139.9
1.1.14.01. Aquaporin-0, alternative packing with lipids 3m9i Ovis aries Eukaryo. plasma 4 24 27.6 ± 1.4 0 ± 0 -139.0
1.1.17.02. Urea transporter 1 4ezc Bos taurus Eukaryo. plasma 3 30 31.2 ± 0.6 0 ± 0 -138.8
1.1.14.01. Aquaporin-0 1ymg Bos taurus Eukaryo. plasma 4 32 31.3 ± 1.2 0 ± 0 -138.4
1.1.12.01. Bacterial cyclic nucleotide regulated ion channel, full structure, with cAMP 4chv Rhizobium loti Bact. Gram-neg inner 4 24 28.4 ± 0.5 0 ± 0 -138.2
1.3.20.01. SusD-SusC complex, a dimer 5t4y Bacteroides thetaiotaomicron Bact. Gram-neg outer 2 44 25.0 ± 0.8 1 ± 0 -137.7
1.1.08.01. F1F0 ATP synthase, F0 complex, conformation 1 2x2v Bacillus pseudofirmus Bact. Gram-pos plas. 13 26 35.3 ± 1.2 0 ± 0 -137.7
1.1.14.01. Aquaglyceroporin 3c02 Plasmodium falciparum Eukaryo. plasma 4 32 30.4 ± 1.3 0 ± 0 -137.4
1.3.16.01. Outer membrane protein C 1osm Klebsiella pneumoniae Bact. Gram-neg outer 3 48 24.0 ± 1.1 0 ± 0 -136.6
1.3.16.01. Porin OmpF 3pox Escherichia coli Bact. Gram-neg outer 3 48 24.0 ± 0.8 0 ± 0 -136.2
1.1.14.01. Aquaporin-1, structure 1 1h6i Homo sapiens Eukaryo. plasma 4 32 30.8 ± 1.1 0 ± 0 -135.6
1.1.02.01. Photosynthetic reaction center, more complete structure 2j8d Rhodobacter sphaeroides Bact. Gram-neg inner 3 11 31.6 ± 1.0 5 ± 0 -135.5
1.1.36.01. CLC-K chloride channel, structure 2 5tr1 Bos taurus Eukaryo. plasma 2 28 31.4 ± 1.0 1 ± 0 -135.2
1.1.57.03. Gamma-secretase complex, structure 6 5fn5 Homo sapiens Endoplasm. reticulum 4 17 30.2 ± 1.2 2 ± 1 -134.8
1.1.01.02. Opioid mu receptor, a dimer 4dkl Mus musculus Eukaryo. plasma 2 14 32.0 ± 1.0 5 ± 0 -134.7
1.1.14.01. Aquaporin Z2 3llq Agrobacterium tumefaciens Bact. Gram-neg inner 4 32 29.8 ± 0.6 0 ± 0 -134.5
1.2.43.02. E1/E2 envelope glycoprotein complex 3j2w Chikungunya virus Viral 8 8 30.8 ± 0.9 2 ± 0 -134.1
1.3.16.01. Phosphoporin (PhoE) 1pho Escherichia coli Bact. Gram-neg outer 3 48 24.1 ± 1.2 0 ± 0 -134.1
1.1.80.01. Phospho-N-acetylmuramoyl-pentapeptide-transferase 5jnq Clostridium bolteae Bact. Gram-pos plas. 2 20 30.6 ± 1.0 3 ± 2 -133.9
1.1.15.01. Glycine receptor, alpha-3, structure 2 5tin Homo sapiens Eukaryo. plasma 5 20 31.0 ± 0.6 0 ± 0 -133.9
1.3.16.01. Porin 1 4d64 Providencia stuartii Bact. Gram-neg outer 3 48 26.0 ± 0.7 0 ± 0 -133.5
1.1.35.03. Citrate-sodium symporter 5a1s Salmonella enterica Bact. Gram-neg inner 2 22 28.6 ± 0.9 5 ± 0 -133.4
1.1.14.01. Aquaporin-5 3d9s Homo sapiens Eukaryo. plasma 4 32 30.3 ± 0.9 0 ± 0 -133.3
1.1.01.02. C-X-C chemokine receptor type 4, inactive, with cyclic peptide antagonist 3oe0 Homo sapiens Eukaryo. plasma 2 14 32.2 ± 2.0 5 ± 6 -133.2
1.1.15.01. Nicotinic acetylcholine receptor, alpha-4/beta-2 5kxi Homo sapiens Eukaryo. plasma 5 20 33.2 ± 0.7 0 ± 0 -133.0
1.1.12.09. Voltage-dependent calcium channel, structure 1 3jbr Oryctolagus cuniculus Eukaryo. plasma 2 28 34.8 ± 0.0 3 ± 0 -132.9
1.1.35.02. Na+/H+ antiporter, inward-open conformation 5bz2 Thermus thermophilus Bact. Gram-neg inner 2 26 29.8 ± 0.5 3 ± 0 -132.9
1.1.01.01. Sensory rhodopsin, trimer 2m3g Nostoc sp. Bact. Gram-neg inner 3 21 31.8 ± 0.8 2 ± 0 -132.8
1.1.26.05. Arginine/agmatine transporter (AdiC), substrate-bound 3l1l Escherichia coli Bact. Gram-neg inner 2 24 28.8 ± 1.4 2 ± 2 -132.0
1.1.01.02. Rhodopsin, constitutively active mutant (metarhodopsin II), dimer 2x72 Bos taurus Eukaryo. plasma 2 14 30.0 ± 0.6 0 ± 0 -132.0
1.1.14.01. Aquaporin AQY1 2w2e Pichia pastoris Eukaryo. plasma 4 32 30.2 ± 0.8 0 ± 0 -131.7
1.1.19.01. Mechanosensitive channel protein MscS 3t9n Thermoanaerobacter tengcongensis Bact. Gram-pos plas. 7 7 28.0 ± 0.7 0 ± 0 -131.5
1.3.16.01. Anion-selective porin 2fgq Comamonas acidovorans Bact. Gram-neg outer 3 48 25.0 ± 0.9 0 ± 0 -130.8
1.1.08.01. F1F0 ATP synthase, F0 complex, conformation 2 3zo6 Bacillus pseudofirmus Bact. Gram-pos plas. 12 24 39.6 ± 1.1 1 ± 0 -130.6
1.1.01.01. Cruxrhodopsin-3 4jr8 Haloarcula vallismortis Archaebac. 3 21 31.8 ± 1.2 0 ± 0 -130.4
1.1.01.02. Opsin, active, retinal-free state, dimer 3cap Bos taurus Eukaryo. plasma 2 14 30.8 ± 1.1 0 ± 0 -130.1
1.1.14.01. Aquaporin-0, open state 2b6p Bos taurus Eukaryo. plasma 4 32 31.1 ± 1.5 0 ± 1 -130.0
1.1.01.01. Bacteriorhodopsin-I 4qi1 Haloquadratum walsbyi Archaebac. 3 21 31.8 ± 1.2 0 ± 0 -129.9
1.1.14.01. Aquaporin AqpM 2f2b Methanobacterium thermoautotrophicum Archaebac. 4 32 29.0 ± 0.8 0 ± 0 -129.9
1.1.14.01. Aquaporin-0, complex with calmodulin 3j41 Ovis aries Eukaryo. plasma 4 24 29.6 ± 0.9 0 ± 0 -129.7
1.1.08.01. F1F0 ATP synthase, F0 complex 2xqu Arthrospira platensis Thylakoid 15 30 31.8 ± 0.8 0 ± 0 -129.7
1.3.16.03. Porin OprP 2o4v Pseudomonas aeruginosa Bact. Gram-neg outer 3 48 23.9 ± 1.1 0 ± 0 -129.6
1.1.02.01. Photosynthetic reaction center 2j8c Rhodobacter sphaeroides Bact. Gram-neg inner 3 11 31.8 ± 0.8 2 ± 0 -129.6
1.1.57.03. Gamma-secretase complex, structure 1 5a63 Homo sapiens Endoplasm. reticulum 4 17 29.8 ± 0.6 5 ± 0 -129.6
1.1.01.02. C-X-C chemokine receptor type 4, inactive, dimer, complex with antagonist 3odu Homo sapiens Eukaryo. plasma 2 14 31.2 ± 1.1 0 ± 0 -129.5
1.1.14.01. Aquaporin-1 1j4n Bos taurus Eukaryo. plasma 4 32 31.8 ± 1.0 0 ± 0 -129.2
1.3.16.01. Porin 2 4d65 Providencia stuartii Bact. Gram-neg outer 3 48 24.4 ± 1.0 0 ± 0 -129.2
1.1.94.01. Ascorbate-specific permease IIC component UlaA, structure 1 4rp8 Escherichia coli Bact. Gram-neg inner 2 22 29.6 ± 0.4 3 ± 0 -129.1
1.3.16.03. Porin OprO 4rjw Pseudomonas aeruginosa Bact. Gram-neg outer 3 48 25.4 ± 0.7 0 ± 0 -129.0
1.1.26.05. Arginine/agmatine antiporter (AdiC), outward-facing structure 1 3h5m Escherichia coli Bact. Gram-neg inner 2 26 29.0 ± 0.8 0 ± 0 -128.9
1.1.35.02. Na+/H+ antiporter 1, inward-open conformation 4czb Methanococcus jannaschii Archaebac. 26 26 27.2 ± 0.5 1 ± 0 -128.3
1.1.36.01. ClC chloride transporter 1kpl Salmonella enterica Bact. Gram-neg inner 2 28 29.3 ± 0.8 2 ± 1 -128.0
1.1.14.01. Aquaporin Sopip2, closed state 2 3cll Spinacia oleracea Eukaryo. plasma 4 27 29.8 ± 0.7 0 ± 0 -127.8
1.1.19.01. Mechanosensitive channel protein MscS, open state 5aji Escherichia coli Bact. Gram-neg inner 7 21 29.8 ± 1.7 0 ± 0 -127.8
1.1.01.01. Bacteriorhodopsin, different loop conformaton 1fbk Halobacterium salinarum Archaebac. 3 21 30.0 ± 1.2 0 ± 0 -127.8
1.1.15.02. Proton-gated ion channel, pore blocker-bound conformation 4twd Erwinia chrysanthemi Bact. Gram-neg inner 5 20 32.0 ± 0.6 0 ± 0 -127.8
1.3.16.02. Porin 3prn Rhodopseudomonas blastica Bact. Gram-neg outer 3 48 23.2 ± 0.5 0 ± 0 -127.6
1.1.02.01. Photosynthetic reaction center, complex with cytochrome c 1l9b Rhodobacter sphaeroides Bact. Gram-neg inner 3 11 31.6 ± 0.8 3 ± 0 -127.3
1.1.02.04. Reaction center-LH1-PufX dimer complex, unit 1 4jcb Rhodobacter sphaeroides Bact. Gram-neg inner 32 40 28.0 ± 0.5 1 ± 0 -127.0
1.1.36.01. CLC-K chloride channel, structure 1 5tqq Bos taurus Eukaryo. plasma 2 28 31.4 ± 0.4 0 ± 0 -126.9
1.1.05.03. Respiratory Nitrate Reductase 1q16 Escherichia coli Bact. Gram-neg inner 2 10 30.1 ± 0.9 0 ± 0 -126.9
1.1.01.01. Halorhodopsin 1e12 Halobacterium salinarum Archaebac. 3 21 31.8 ± 1.4 0 ± 1 -126.7
1.1.35.01. Sodium/proton antiporter 1 (NhaA), dimer 3fi1 Escherichia coli Bact. Gram-neg inner 2 24 28.4 ± 1.6 2 ± 1 -126.7
1.1.02.04. Reaction center-LH1-PufX dimer complex, unit 2 4jc9 Rhodobacter sphaeroides Bact. Gram-neg inner 32 40 28.4 ± 0.7 1 ± 0 -126.6
1.3.16.01. Osmoporin OMPC 2j1n Escherichia coli Bact. Gram-neg outer 3 48 25.1 ± 1.2 0 ± 2 -126.2
1.1.14.01. Aquaporin-4 2d57 Rattus norvegicus Eukaryo. plasma 4 32 29.8 ± 1.1 0 ± 0 -126.2
1.1.07.02. Bd-type quinol oxidase 5doq Geobacillus thermodenitrificans Bact. Gram-pos plas. 3 19 29.2 ± 0.8 9 ± 1 -126.2
1.1.14.01. Aquaporin-2, conformation 2 4oj2 Homo sapiens Eukaryo. plasma 4 24 29.0 ± 0.7 0 ± 0 -125.9
1.1.15.02. Proton-gated ion channel, inactive conformation 4 4a97 Erwinia chrysanthemi Bact. Gram-neg inner 5 40 31.8 ± 0.5 0 ± 0 -125.8
1.1.01.02. Rhodopsin, inactive state, a dimer 2i36 Bos taurus Eukaryo. plasma 2 14 30.0 ± 1.4 4 ± 4 -125.6
1.1.01.02. Rhodopsin, active (metarhodopsin II), without transducin peptide 3pxo Bos taurus Eukaryo. plasma 2 14 31.8 ± 1.2 0 ± 0 -125.4
1.3.19.03. MOMP porin 5ldv Campylobacter jejuni Bact. Gram-neg outer 3 54 25.4 ± 0.6 0 ± 0 -125.2
1.1.15.01. Glutamate-gated chloride channel GluCl, POPC-bound conformation 4tnw Caenorhabditis elegans Eukaryo. plasma 5 20 30.6 ± 0.9 0 ± 0 -125.0
1.1.38.02. Lipid II flippase MurJ, inward-facing conformation 5t77 Thermosipho africanus Bact. Gram-neg inner 1 14 30.6 ± 1.4 3 ± 0 -124.8
1.1.24.01. Bestrophin-1 4rdq Gallus gallus Eukaryo. plasma 4 16 30.8 ± 1.0 0 ± 0 -124.8
1.1.26.05. Arginine/agmatine antiporter (AdiC), outward-facing conformation 3hqk Salmonella enterica Bact. Gram-neg inner 2 26 29.8 ± 1.0 0 ± 0 -124.6
1.1.17.02. Urea transporter 3k3f Desulfovibrio vulgaris Bact. Gram-neg inner 3 30 29.4 ± 0.8 0 ± 0 -124.4
1.1.104.01. Trimeric intracellular cation channel 5h36 Rhodobacter sphaeroides Bact. Gram-neg inner 3 21 31.0 ± 1.0 0 ± 0 -124.3
1.1.10.01. ABC transporter permease HI1471 2nq2 Haemophilus influenzae Bact. Gram-neg inner 2 20 31.9 ± 0.9 1 ± 1 -124.2
1.3.16.01. OmpC porin 5fvn Enterobacter cloacae Bact. Gram-neg outer 3 48 23.2 ± 0.6 0 ± 0 -124.2
1.2.26.01. Outer membrane lipoprotein Wza 2j58 Escherichia coli Bact. Gram-neg outer 8 8 31.1 ± 0.8 0 ± 0 -123.8
1.1.10.01. ABC transporter BtuCD, complex with BtuF, structure 1 2qi9 Escherichia coli Bact. Gram-neg inner 2 22 29.4 ± 0.9 4 ± 4 -123.5
1.3.16.01. Porin OmpF 3nsg Salmonella enterica Bact. Gram-neg outer 3 48 23.6 ± 0.8 0 ± 0 -123.4
1.1.10.01. ABC transporter BtuCD, complex with BtuF, structure 2 4dbl Escherichia coli Bact. Gram-neg inner 2 20 29.4 ± 1.0 4 ± 0 -123.4
1.1.01.01. Sensory rhodopsin II, tetramer, structure 1 1h2s Natronomonas pharaonis Archaebac. 4 18 30.5 ± 1.1 0 ± 0 -123.4
1.1.16.01. Glutamate receptor 2, with TARP channel 5kk2 Rattus norvegicus Eukaryo. plasma 8 32 34.0 ± 0.4 1 ± 0 -123.2
1.1.02.06. Light-Harvesting Complex II 2bhw Pisum sativum Thylakoid 3 9 29.4 ± 1.0 0 ± 0 -123.2
1.1.11.01. Holo-translocon 5mg3 Escherichia coli Bact. Gram-neg inner 6 29 30.6 ± 0.8 5 ± 0 -123.2
1.1.14.01. Aquaporin-4 3gd8 Homo sapiens Eukaryo. plasma 4 32 29.8 ± 1.1 0 ± 1 -122.9
1.1.97.01. Mycobacterial Insig homolog MvINS 4xu4 Mycobacterium vanbaalenii Bact. Gram-pos plas. 3 18 30.0 ± 0.9 0 ± 0 -122.0
1.1.02.01. Photosynthetic reaction center, complex with cytochrome c 1dxr Rhodopseudomonas viridis Bact. Gram-neg inner 3 11 31.8 ± 0.7 5 ± 0 -121.8
1.1.19.01. Mechanosensitive channel protein MscS, slightly different conf. 3udc Thermoanaerobacter tengcongensis Bact. Gram-pos plas. 7 7 32.2 ± 0.7 0 ± 0 -121.8
1.1.15.02. Proton-gated ion channel, conformation 4 5heo Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.0 ± 0.8 0 ± 0 -121.8
1.1.18.01. Mechanosensitive channel MscL, closed state 4y7k Methanosarcina acetivorans Archaebac. 5 10 31.8 ± 0.1 0 ± 0 -121.6
1.1.34.01. Mitochondrial ADP-ATP carrier, dimer, conformation 1 4c9h Saccharomyces cerevisiae Mitochon. inner 2 12 30.4 ± 0.7 0 ± 0 -121.4
1.1.01.01. Bacteriorhodopsin 5azd Thermus thermophilus Bact. Gram-neg inner 4 28 30.0 ± 0.5 3 ± 1 -121.3
1.1.01.01. Bacteriorhodopsin 1m0l Halobacterium salinarum Archaebac. 3 21 31.8 ± 1.1 0 ± 1 -121.1
1.1.12.04. Transient receptor potential cation channel A1, TRPA1 3j9p Homo sapiens Eukaryo. plasma 4 24 26.8 ± 0.3 0 ± 0 -121.0
1.1.10.01. ABC transporter BtuCD, symmetric structure 1l7v Escherichia coli Bact. Gram-neg inner 2 22 30.7 ± 1.1 0 ± 1 -121.0
1.1.17.01. Ammonium transporter MEP2 5aex Saccharomyces cerevisiae Eukaryo. plasma 3 33 29.4 ± 1.4 0 ± 0 -121.0
1.3.16.01. Osmoporin OMPC, isoform 2 2ixw Escherichia coli Bact. Gram-neg outer 3 48 24.5 ± 1.0 0 ± 0 -121.0
1.1.36.01. ClC chloride transporter 3nd0 Synechocystis sp. Bact. Gram-neg inner 2 28 29.8 ± 0.7 0 ± 1 -120.9
1.1.35.02. Na+/H+ antiporter 4bwz Thermus thermophilus Bact. Gram-neg inner 2 26 29.6 ± 0.6 0 ± 0 -120.8
1.1.12.02. G protein-activated inward rectifier potassium channel 2 4kfm Mus musculus Eukaryo. plasma 4 8 33.6 ± 1.2 0 ± 0 -120.7
1.1.10.03. Oligosaccharide flippase PglK, apo-inward state 1 5c78 Campylobacter jejuni Bact. Gram-neg inner 12 2 31.0 ± 1.1 2 ± 1 -120.6
1.1.10.03. Oligosaccharide flippase PglK, apo-inward state 2 5c76 Campylobacter jejuni Bact. Gram-neg inner 2 12 32.0 ± 0.8 1 ± 0 -120.5
1.1.12.02. Potassium channel Kir 2.2, complex with pyrophosphate lipid 3spc Gallus gallus Eukaryo. plasma 4 8 30.6 ± 1.2 0 ± 0 -120.3
1.1.12.02. Potassium channel Kir 2.2, structure 1 3jyc Gallus gallus Eukaryo. plasma 4 8 30.5 ± 1.4 0 ± 1 -119.9
1.1.10.01. ABC transporter BtuCD, a nucleotide-bound outward facing state 4r9u Escherichia coli Bact. Gram-neg inner 2 20 28.6 ± 1.3 1 ± 1 -119.8
1.1.16.01. Glutamate receptor 2, apo state, structure 2 5l1b Rattus norvegicus Eukaryo. plasma 4 12 36.0 ± 0.8 3 ± 1 -119.7
1.1.24.01. Bestrophin ion channel 4wd8 Klebsiella pneumoniae Bact. Gram-neg inner 5 20 27.4 ± 0.6 0 ± 0 -119.7
1.1.15.01. Nicotinic acetylcholine receptor, closed state 2bg9 Torpedo marmorata Eukaryo. plasma 5 20 30.1 ± 1.1 3 ± 0 -119.6
1.1.07.01. Bacterial cytochrome c oxidase, cbb3 type 3mk7 Pseudomonas stutzeri Bact. Gram-neg inner 4 17 32.8 ± 1.2 4 ± 4 -119.2
1.1.26.06. Uric acid-xanthine permease 5i6c Emericella nidulans Eukaryo. plasma 2 28 29.2 ± 1.0 0 ± 0 -119.2
1.1.01.01. Bacteriorhodopsin, trimer, complex with annular lipids 2zzl Halobacterium salinarum Archaebac. 3 21 29.8 ± 0.6 0 ± 0 -119.0
1.1.15.02. Proton-gated ion channel, inactive conformation 3 3rqw Erwinia chrysanthemi Bact. Gram-neg inner 5 20 29.8 ± 0.4 0 ± 0 -118.8
1.1.05.04. Fumarate reductase 2bs2 Wolinella succinogenes Bact. Gram-neg inner 2 10 31.4 ± 1.3 2 ± 0 -118.8
1.1.14.01. Aquaporin Z 1rc2 Escherichia coli Bact. Gram-neg inner 4 32 29.7 ± 1.3 0 ± 0 -118.7
1.1.10.01. ABC transporter BtuCD, nucleotide-bound state 4fi3 Escherichia coli Bact. Gram-neg inner 2 20 29.0 ± 1.0 0 ± 0 -118.3
1.1.35.02. Na+/H+ antiporter, structure 1 4cz8 Pyrococcus abyssi Archaebac. 2 26 29.8 ± 0.9 2 ± 0 -118.2
1.1.72.02. Antibiotic resistance efflux pump MtrF 4r1i Neisseria gonorrhoeae Bact. Gram-neg inner 2 22 28.9 ± 1.4 0 ± 0 -118.2
1.3.16.01. Osmoporin OMPC 3upg Salmonella typhimurium Bact. Gram-neg outer 3 48 23.4 ± 0.7 0 ± 0 -118.0
1.3.18.01. Maltoporin 1af6 Escherichia coli Bact. Gram-neg outer 3 54 25.1 ± 0.7 0 ± 0 -117.9
1.1.14.01. Aquaporin-2, conformation 1 4nef Homo sapiens Eukaryo. plasma 4 24 28.6 ± 1.3 0 ± 0 -117.8
1.1.01.05. Metabotropic glutamate receptor 1 4or2 Homo sapiens Eukaryo. plasma 2 14 31.4 ± 0.9 1 ± 0 -117.3
1.3.16.01. Porin B (PorB), different strain, conformation 2 3wi5 Neisseria meningitidis Bact. Gram-neg outer 3 48 25.4 ± 0.9 0 ± 0 -117.2
1.1.14.01. Aquaporin Sopip2, closed state 1z98 Spinacia oleracea Eukaryo. plasma 4 32 28.1 ± 2.2 0 ± 0 -117.2
1.1.12.06. Potassium channel subfamily K member 10, closed state 4xdk Homo sapiens Eukaryo. plasma 2 8 32.2 ± 0.7 5 ± 2 -117.1
1.1.35.02. Na+/H+ antiporter, structure 2 4cz9 Pyrococcus abyssi Archaebac. 2 26 27.2 ± 0.8 1 ± 0 -116.9
1.1.01.01. Sensory rhodopsin II, tetramer, structure 2 5jje Natronomonas pharaonis Archaebac. 4 18 30.2 ± 0.8 0 ± 0 -116.8
1.1.16.01. GluN1/GluN2A/GluN2B NMDA receptor, structure 1 5uow Xenopus laevis Eukaryo. plasma 4 12 31.0 ± 0.6 3 ± 0 -116.4
1.1.08.01. ATP synthase of chloroplast 2w5j Spinacia oleracea Thylakoid 14 28 32.8 ± 0.7 0 ± 0 -116.3
1.1.01.01. Sensory rhodopsin, dimer 4tl3 Nostoc sp. Bact. Gram-neg inner 2 17 30.6 ± 1.1 0 ± 0 -116.0
1.1.02.01. Photosynthetic reaction center, complex with cytochrome c 1eys Thermochromatium tepidum Bact. Gram-neg inner 3 11 31.6 ± 1.0 2 ± 0 -116.0
1.1.12.01. Potassium channel KcsA, 14.5 A opening conformer 3fb5 Streptomyces lividans Bact. Gram-pos plas. 4 8 33.7 ± 0.9 0 ± 0 -115.9
1.1.12.01. Voltage-gated K+ channel 4h33 Listeria monocytogenes Bact. Gram-pos plas. 4 8 33.2 ± 1.9 0 ± 0 -115.9
1.1.25.05. Proton-dependent oligopeptide transporter, conformation 3 4ikx Geobacillus kaustophilus Bact. Gram-pos plas. 1 14 31.0 ± 1.0 10 ± 0 -115.9
1.1.08.01. F1F0 ATP synthase, F0F1 complex, more complete model 4b2q Saccharomyces cerevisiae Mitochon. inner 10 20 38.4 ± 0.9 0 ± 0 -115.7
1.1.14.01. Aquaporin-4, different conformation of loops with lipids 2zz9 Rattus norvegicus Eukaryo. plasma 4 28 29.5 ± 0.7 0 ± 0 -115.6
1.1.25.05. Proton-dependent oligopeptide transporter, conformation 2 4iky Geobacillus kaustophilus Bact. Gram-pos plas. 1 14 31.8 ± 1.3 4 ± 0 -115.6
1.1.36.01. ClC chloride transporter 1ots Escherichia coli Bact. Gram-neg inner 2 28 29.7 ± 0.8 0 ± 0 -115.3
1.3.16.02. Porin 2por Rhodobacter capsulatus Bact. Gram-neg outer 3 48 23.4 ± 0.6 0 ± 0 -114.8
1.1.25.05. Di-or tripeptide:H+ symporter, inward open, structure 1 4aps Streptococcus thermophilus Bact. Gram-pos plas. 1 14 31.8 ± 0.7 13 ± 0 -114.6
1.1.10.01. Hemin transport system permease, HmuU 4g1u Yersinia pestis Bact. Gram-neg inner 2 20 29.8 ± 0.5 0 ± 0 -114.3
1.1.25.05. Di- or tripeptide transporter 4w6v Yersinia enterocolitica Bact. Gram-neg inner 1 14 29.8 ± 1.2 12 ± 1 -113.6
1.1.14.01. Aquaporin Sopip2, open state 2b5f Spinacia oleracea Eukaryo. plasma 4 32 29.4 ± 1.1 2 ± 2 -113.0
1.1.104.01. Trimeric intracellular cation channel 5h35 Sulfolobus solfataricus Archaebac. 3 21 27.4 ± 0.8 0 ± 0 -112.8
1.3.16.01. Porin B (PorB), different strain 3wi4 Neisseria meningitidis Bact. Gram-neg outer 3 48 23.4 ± 0.6 0 ± 0 -112.6
1.1.25.05. Di-or tripeptide:H+ symporter, inward open, structure 3 5d6k Streptococcus thermophilus Bact. Gram-pos plas. 1 14 32.8 ± 1.0 5 ± 0 -112.6
1.1.01.01. Bacteriorhodopsin, K state, with lipids 1iw6 Halobacterium salinarum Archaebac. 3 21 30.0 ± 0.6 0 ± 0 -112.6
1.1.14.02. Nitrite transporter NirC 4fc4 Salmonella typhimurium Bact. Gram-neg inner 5 35 33.8 ± 0.0 0 ± 0 -112.5
1.1.07.01. Bacterial cytochrome c oxidase 3s8g Thermus thermophilus Bact. Gram-neg inner 3 15 31.2 ± 1.1 7 ± 0 -112.3
1.1.42.01. Nicotinamide riboside transporter PnuC 4qtn Neisseria mucosa Bact. Gram-neg inner 3 24 26.8 ± 0.7 0 ± 0 -112.0
1.1.12.01. Potassium channel KcsA 1s5h Streptomyces coelicolor Bact. Gram-pos plas. 4 8 33.7 ± 1.3 0 ± 1 -111.9
1.1.12.02. Potassium channel Kirbac1.1, closed state 1p7b Burkholderia pseudomallei Bact. Gram-neg inner 4 8 33.1 ± 1.3 0 ± 0 -111.9
1.1.16.01. GluN1/GluN2A/GluN2B NMDA receptor, structure 2 5up2 Xenopus laevis Eukaryo. plasma 4 12 31.0 ± 0.6 1 ± 0 -111.8
1.1.10.03. Type-1 secretion system ABC transporter (HlyB-like) 5l22 Aquifex aeolicus Bact. Gram-neg inner 2 12 33.0 ± 1.4 1 ± 0 -111.8
1.1.92.01. Na(+)-translocating NADH-quinone reductase 4p6v Vibrio cholerae Bact. Gram-neg inner 5 24 28.8 ± 0.3 5 ± 0 -111.8
1.1.08.01. ATP synthase of chloroplast 3v3c Pisum sativum Thylakoid 14 28 32.0 ± 1.0 0 ± 0 -111.5
1.1.11.01. Protein translocase SecY, resting state 5aww Thermus thermophilus Bact. Gram-neg inner 3 13 29.8 ± 1.2 5 ± 0 -111.5
1.1.12.01. Potassium channel KcsA 1r3j Streptomyces lividans Bact. Gram-pos plas. 4 8 34.8 ± 1.2 0 ± 0 -111.0
1.1.25.05. Proton-dependent oligopeptide transporter, conformation 1 4ikv Geobacillus kaustophilus Bact. Gram-pos plas. 1 14 30.8 ± 1.5 5 ± 0 -110.9
1.1.10.08. Multidrug resistance protein 1 (MRP1), structure 1 5uj9 Homo sapiens Eukaryo. plasma 1 17 31.0 ± 0.2 7 ± 0 -110.7
1.1.01.01. Deltarhodopsin 4fbz Haloterrigena thermotolerans Archaebac. 3 21 31.6 ± 0.8 0 ± 0 -110.6
1.1.25.06. Glucose transporter GLUT5, outward-open 4ybq Rattus norvegicus Eukaryo. plasma 1 12 32.4 ± 3.0 5 ± 0 -110.6
1.1.10.03. Multidrug ABC transporter SAV1866, closed state 2hyd Staphylococcus aureus Bact. Gram-pos plas. 2 12 31.8 ± 1.7 3 ± 3 -110.5
1.1.25.05. Di-or tripeptide:H+ symporter, inward open, structure 2 4d2d Streptococcus thermophilus Bact. Gram-pos plas. 1 14 31.0 ± 1.1 7 ± 0 -109.9
1.3.18.01. Maltoporin 2mpr Salmonella enterica Bact. Gram-neg outer 3 54 24.5 ± 1.0 0 ± 0 -109.7
1.1.26.08. Boron transporter 1 5l25 Arabidopsis thaliana Eukaryo. plasma 2 28 30.8 ± 0.5 0 ± 0 -109.6
1.1.09.01. Plasma membrane ATPase 1mhs Neurospora crassa Eukaryo. plasma 2 20 29.5 ± 0.2 7 ± 0 -109.6
1.1.15.01. Nicotinic acetylcholine receptor, partially open state 4aq9 Torpedo marmorata Eukaryo. plasma 5 20 30.8 ± 0.8 2 ± 0 -109.5
1.1.16.01. Glutamate receptor 2, with stargazin, structure 2 5kbu Rattus norvegicus Eukaryo. plasma 4 20 33.6 ± 1.4 0 ± 0 -109.5
1.1.12.03. Multi-ligand gated K(+) channel, TrkA, mutant 4gx0 Geobacter sulfurreducens Bact. Gram-neg inner 4 8 31.8 ± 1.3 0 ± 0 -109.5
1.1.103.01. ExbB/ExbD complex, structure 2 5sv1 Escherichia coli Bact. Gram-neg inner 6 16 30.8 ± 0.5 2 ± 0 -109.5
1.1.10.04. P-glycoprotein, inward-facing conformation 5 4q9j Mus musculus Eukaryo. plasma 1 12 31.8 ± 0.7 7 ± 0 -109.4
1.1.10.03. ABC-type bacteriocin transporter 4ry2 Clostridium thermocellum Bact. Gram-pos plas. 2 12 33.8 ± 0.2 1 ± 0 -109.4
1.1.07.01. Nitric oxide reductase 3ayf Bacillus stearothermophilus Bact. Gram-pos plas. 1 14 31.6 ± 0.8 8 ± 0 -109.3
1.1.12.02. Potassium channel Kirbac1.1, closed state, refined 2wll Burkholderia pseudomallei Bact. Gram-neg inner 4 8 33.4 ± 2.4 0 ± 0 -109.1
1.1.12.02. Potassium channel Kir 2.2, complex with inositol lipid 3spg Gallus gallus Eukaryo. plasma 4 8 30.8 ± 1.2 0 ± 0 -109.1
1.1.15.02. Proton-gated ion channel, inactive conformation 5 5lg3 Erwinia chrysanthemi Bact. Gram-neg inner 20 5 33.8 ± 1.1 0 ± 0 -108.7
1.1.60.01. Protease GlpG, crystallographic trimer 4h1d Escherichia coli Bact. Gram-neg inner 3 18 27.0 ± 0.1 2 ± 0 -108.7
1.1.12.06. Potassium channel subfamily K member 1 3ukm Homo sapiens Eukaryo. plasma 2 8 31.8 ± 1.0 0 ± 0 -108.7
1.1.12.02. Potassium channel Kir 2.2, structure 2 5kuk Gallus gallus Eukaryo. plasma 4 8 30.8 ± 0.2 0 ± 0 -108.3
1.1.35.02. Na+/H+ antiporter, outward-open conformation 5bz3 Thermus thermophilus Bact. Gram-neg inner 2 26 29.2 ± 0.8 0 ± 0 -108.2
1.1.15.01. Glutamate-gated chloride channel GluCl, with partial agonist 3rhw Caenorhabditis elegans Eukaryo. plasma 5 20 30.2 ± 0.7 0 ± 0 -107.9
1.1.12.02. G protein-activated inward rectifier potassium channel 2, diff. conf. 3syq Mus musculus Eukaryo. plasma 4 8 31.6 ± 0.6 0 ± 0 -107.9
1.1.10.02. Maltose transporter MalFGK, complex with protein EIIAglc 4jbw Escherichia coli Bact. Gram-neg inner 2 14 29.8 ± 0.8 4 ± 1 -107.8
1.1.07.01. Nitric oxide reductase 3o0r Pseudomonas aeruginosa Bact. Gram-neg inner 2 13 31.7 ± 1.6 5 ± 0 -107.7
1.1.15.02. Proton-gated ion channel, inactive conformation 1 2vl0 Erwinia chrysanthemi Bact. Gram-neg inner 5 20 31.8 ± 1.3 0 ± 0 -107.6
1.1.12.06. Potassium channel subfamily K member 2 4twk Homo sapiens Eukaryo. plasma 2 8 29.4 ± 0.8 2 ± 0 -107.6
1.1.15.02. Proton-gated ion channel - human GLRA1 channel chimera 4x5t Gloeobacter violaceus Bact. Gram-neg inner 5 20 35.8 ± 0.1 0 ± 0 -107.4
1.1.12.01. Potassium channel KcsA, full-length, closed 3eff Streptomyces lividans Bact. Gram-pos plas. 4 8 31.8 ± 1.3 0 ± 0 -107.3
1.1.10.03. Microcin-J25 export ATP-binding/permease protein McjD 4pl0 Escherichia coli Bact. Gram-neg inner 2 12 32.4 ± 0.8 0 ± 0 -107.2
1.1.10.02. Maltose transporter MalFGK, a pre-translocation state 3puz Escherichia coli Bact. Gram-neg inner 2 14 29.0 ± 0.8 7 ± 0 -107.2
1.1.12.06. Potassium channel subfamily K member 4, structure 4 4ruf Homo sapiens Eukaryo. plasma 2 8 31.8 ± 0.8 3 ± 1 -106.6
1.1.12.06. Potassium channel subfamily K member 4, structure 2 4i9w Homo sapiens Eukaryo. plasma 2 8 30.8 ± 1.4 6 ± 0 -106.2
1.1.15.01. Glutamate-gated chloride channel GluCl, apo (non-conducting state) 4tnv Caenorhabditis elegans Eukaryo. plasma 5 20 30.8 ± 1.5 0 ± 0 -106.1
1.1.25.05. Nitrate transporter NRT1/ PTR, dimer 4oh3 Arabidopsis thaliana Eukaryo. plasma 2 24 29.0 ± 0.9 0 ± 0 -106.0
1.1.12.01. NaK potassium channel 2ahy Bacillus cereus Bact. Gram-pos plas. 4 8 29.5 ± 0.7 0 ± 1 -105.7
1.1.10.04. P-glycoprotein, inward-facing conformation 3 4q9l Mus musculus Eukaryo. plasma 1 12 31.8 ± 1.1 5 ± 1 -105.6
1.1.25.05. Glutathione uptake transporter, structure 2 4uvm Shewanella oneidensis Bact. Gram-neg inner 1 14 29.8 ± 0.7 10 ± 0 -105.3
1.1.32.01. Proton glutamate symport protein, inward-facing state 3 4x2s Pyrococcus horikoshii Archaebac. 3 30 27.0 ± 0.7 10 ± 0 -105.3
1.1.74.01. Calcium release-activated calcium channel protein 1 4hkr Drosophila melanogaster Eukaryo. plasma 6 24 30.0 ± 1.6 0 ± 0 -105.2
1.1.05.01. Polysulfide reductase, inactive state 2vpz Thermus thermophilus Bact. Gram-neg inner 2 16 29.8 ± 1.5 1 ± 0 -105.2
1.1.12.06. Potassium channel subfamily K member 4, structure 3 4rue Homo sapiens Eukaryo. plasma 2 8 33.6 ± 0.9 2 ± 0 -105.1
1.1.12.01. Potassium channel KscA, complex with charibdotoxin 2a9h Streptomyces lividans Bact. Gram-pos plas. 4 8 31.8 ± 1.4 0 ± 1 -105.1
1.1.10.04. Multidrug resistance protein pgp-1 4f4c Caenorhabditis elegans Eukaryo. plasma 1 14 32.0 ± 1.8 6 ± 0 -105.1
1.1.10.03. ABC transporter, inward-facing conformation 3qf4 Thermotoga maritima Bact. Gram-neg inner 2 12 32.0 ± 0.8 2 ± 0 -104.9
1.1.108.01. ABC transporter LptB2FG 5x5y Pseudomonas aeruginosa Bact. Gram-neg inner 2 12 31.0 ± 0.6 5 ± 1 -104.8
1.1.08.01. F-type Sodium ATPase 1yce Ilyobacter tartaricus Bact. Gram-neg inner 11 22 37.0 ± 0.5 0 ± 0 -104.0
1.1.09.01. Sodium-potassium pump, Na+ bound state 4hqj Sus scrofa Eukaryo. plasma 3 12 31.0 ± 1.3 11 ± 2 -104.0
1.1.10.04. P-glycoprotein, inward-facing conformation 8 5kpj Mus musculus Eukaryo. plasma 1 12 31.0 ± 0.4 7 ± 0 -103.9
1.1.10.05. Sterol transporter ABCG5/ABCG8 5do7 Homo sapiens Eukaryo. plasma 2 12 30.8 ± 1.1 5 ± 0 -103.8
1.1.10.08. Multidrug resistance protein 1 (MRP1), structure 2 5uja Homo sapiens Eukaryo. plasma 1 17 31.4 ± 0.8 16 ± 0 -103.8
1.3.18.01. Sucrose-specific porin 1a0s Salmonella enterica Bact. Gram-neg outer 3 54 23.8 ± 1.1 0 ± 0 -103.5
1.1.11.01. Protein translocase SecY, peptide-bound 5ch4 Thermus thermophilus Bact. Gram-neg inner 3 13 29.8 ± 1.5 5 ± 1 -103.5
1.1.05.01. Polysulfide reductase, substrate-bound state 2vpx Thermus thermophilus Bact. Gram-neg inner 2 16 27.1 ± 1.1 0 ± 1 -103.3
1.1.10.04. P-glycoprotein, inward-facing conformation 4 4q9i Mus musculus Eukaryo. plasma 1 12 31.8 ± 0.9 5 ± 1 -103.0
1.1.08.01. F1F0 ATP synthase, F0 complex 4bem Acetobacterium woodii Bact. Gram-pos plas. 10 22 34.8 ± 1.1 0 ± 0 -102.9
1.1.25.05. Glutathione uptake transporter, structure 1 2xut Shewanella oneidensis Bact. Gram-neg inner 1 14 30.9 ± 1.4 10 ± 0 -102.5
1.1.10.04. P-glycoprotein, inward-facing conformation 7 5ko2 Mus musculus Eukaryo. plasma 1 12 33.0 ± 1.0 1 ± 1 -102.4
1.1.103.01. ExbB/ExbD complex, structure 1 5sv0 Escherichia coli Bact. Gram-neg inner 5 15 31.8 ± 0.8 1 ± 1 -102.1
1.3.16.01. Porin B (PorB) 3a2s Neisseria meningitidis Bact. Gram-neg outer 3 48 24.4 ± 1.0 0 ± 0 -102.1
1.1.25.02. Lactose permease LacY, structure 5 4oaa Escherichia coli Bact. Gram-neg inner 1 12 32.6 ± 1.6 2 ± 2 -101.7
1.1.07.01. Nitric oxide reductase 4xyd Roseobacter denitrificans Bact. Gram-neg inner 2 13 31.4 ± 1.1 7 ± 1 -101.6
1.1.25.05. Dipeptide permease D 4q65 Escherichia coli Bact. Gram-neg inner 1 14 30.2 ± 0.8 7 ± 1 -101.4
1.1.26.01. Dopamine transporter, outward-facing conformation 4m48 Drosophila melanogaster Eukaryo. plasma 1 12 30.8 ± 1.6 12 ± 0 -101.0
1.1.25.05. Bacterial proton:oligopeptide symporter, structure 2 4tpg Shewanella oneidensis Bact. Gram-neg inner 14 14 30.8 ± 1.0 9 ± 0 -100.8
1.1.52.01. Transmembrane oligosaccharyl transferase 3wak Archaeoglobus fulgidus Archaebac. 1 13 29.8 ± 0.6 12 ± 0 -100.8
1.1.16.01. Glutamate receptor 2, with stargazin, structure 1 5kbt Rattus norvegicus Eukaryo. plasma 4 16 34.0 ± 0.6 2 ± 1 -100.7
1.1.10.02. Molybdate transporter ModBC, open state 2onk Archaeoglobus fulgidus Archaebac. 2 12 32.0 ± 1.7 0 ± 1 -100.7
1.1.11.01. Protein translocase SecY, pre-open state 2zjs Thermus thermophilus Bact. Gram-neg inner 2 11 30.7 ± 1.2 7 ± 0 -100.7
1.1.10.04. P-glycoprotein, inward-facing conformation 1a 3g5u Mus musculus Eukaryo. plasma 1 12 31.8 ± 1.2 4 ± 0 -100.6
1.1.01.01. Chimaera of channelrhodopsins 1 and 2 3ug9 Chlamydomonas reinhardtii Eukaryo. plasma 2 14 31.0 ± 1.2 0 ± 0 -100.3
1.1.09.01. Sodium-potassium pump, Na+ bound E1P preceeding state 3wgu Sus scrofa Eukaryo. plasma 3 12 30.8 ± 1.1 4 ± 0 -100.2
1.1.12.01. NaK-NavSulP chimera channel 3vou Sulfitobacter sp. Bact. Gram-neg inner 4 8 30.4 ± 0.8 0 ± 0 -100.1
1.1.10.02. Alg transporter 4tqu Sphingomonas sp. Bact. Gram-neg inner 2 12 30.6 ± 0.8 3 ± 0 -100.1
1.1.16.01. Glutamate receptor 2, with noncompetitive inhibitor 5l1h Rattus norvegicus Eukaryo. plasma 4 12 36.4 ± 0.7 0 ± 0 -100.1
1.1.12.08. Ryanodine receptor 1, open structure 5gl1 Oryctolagus cuniculus Endoplasm. reticulum 4 24 33.8 ± 0.0 4 ± 0 -100.0
1.1.12.01. Potassium channel KvAP 2a0l Aeropyrum pernix Archaebac. 4 12 29.5 ± 1.1 0 ± 0 -100.0
1.1.23.01. TMEM16 lipid scramblase 4wis Nectria haematococca Eukaryo. plasma 2 20 29.8 ± 0.9 1 ± 1 -99.7
1.1.11.01. Protein translocase SecY, closed state 2zqp Thermus thermophilus Bact. Gram-neg inner 2 11 29.8 ± 0.4 9 ± 0 -99.4
1.1.26.02. Sodium-hydantoin transporter Mhp1, outward-facing conformation 2 2jln Mycobacterium liquefaciens Bact. Gram-pos plas. 1 12 29.8 ± 1.5 16 ± 0 -98.9
1.1.26.05. Glutamate/gamma-aminobutyrate antiporter 4dji Escherichia coli Bact. Gram-neg inner 1 12 30.0 ± 1.1 10 ± 1 -98.9
1.1.12.06. Potassium channel subfamily K member 10, open state 4bw5 Homo sapiens Eukaryo. plasma 2 8 31.2 ± 0.9 5 ± 0 -98.5
1.1.10.03. Lipid flippase MsbA, open state 3b60 Salmonella enterica Bact. Gram-neg inner 2 12 31.8 ± 0.9 0 ± 0 -98.5
1.1.01.04. Smoothened homolog, dimer, structure 1 4jkv Homo sapiens Eukaryo. plasma 2 14 31.9 ± 1.2 0 ± 0 -98.5
1.1.84.01. Phosphatidylinositolphosphate synthase, structure 1 5d92 Renibacterium salmoninarum Bact. Gram-pos plas. 2 12 31.8 ± 1.4 0 ± 1 -98.3
1.1.10.02. Maltose transporter MalFGK, inward conformation, TMH 1 deleted 3fh6 Escherichia coli Bact. Gram-neg inner 2 13 29.9 ± 0.6 3 ± 1 -97.8
1.1.01.01. Bacteriorhodopsin, from cubic phase 1ap9 Halobacterium salinarum Archaebac. 3 21 30.6 ± 1.2 0 ± 0 -97.8
1.1.06.02. Ascorbate-dependent oxidoreductase 4o6y Arabidopsis thaliana Eukaryo. plasma 2 12 31.0 ± 1.3 1 ± 0 -97.6
1.1.12.01. Sodium channel BacNaV 4lto Alkalilimnicola ehrlichei Bact. Gram-neg inner 4 8 30.6 ± 1.1 2 ± 1 -97.3
1.1.61.01. Microsomal prostaglandin E synthase 1, structure 1 3dww Homo sapiens Endoplasm. reticulum 3 12 31.9 ± 1.1 2 ± 1 -97.3
1.2.43.02. E1/E2 envelope glycoprotein complex 3j0c Venezuelan equine encephalitis virus Viral 8 8 31.2 ± 1.7 3 ± 1 -96.9
1.1.84.01. CDP-alcohol phosphatidyltransferase 4o6m Archaeoglobus fulgidus Archaebac. 2 12 30.0 ± 1.3 3 ± 1 -96.6
1.1.37.01. Divalent metal cation transporter MntH 5m87 Eremococcus coleocola Bact. Gram-pos plas. 1 12 30.2 ± 0.6 10 ± 0 -96.6
1.1.38.01. MATE multidrug transporter DinF-BH 4lz6 Bacillus halodurans Bact. Gram-pos plas. 1 12 31.0 ± 1.1 5 ± 1 -96.5
1.1.26.02. Sodium-hydantoin transporter Mhp1, outward-facing conformation 1 4d1b Mycobacterium liquefaciens Bact. Gram-pos plas. 1 12 29.8 ± 0.9 17 ± 0 -96.4
1.1.09.01. Sodium-potassium pump, E2P state 2zxe Squalus acanthias Eukaryo. plasma 3 12 31.9 ± 1.8 9 ± 0 -96.3
1.1.25.06. Glucose transporter GLUT1 4pyp Homo sapiens Eukaryo. plasma 1 12 31.8 ± 0.7 6 ± 0 -96.2
1.1.12.01. Sodium channel BacNaV, channel neck mutants 5hj8 Alkalilimnicola ehrlichei Bact. Gram-neg inner 4 8 30.6 ± 1.1 0 ± 0 -96.1
1.1.37.01. Divalent metal cation transporter MntH, structure 1 5m94 Staphylococcus capitis Bact. Gram-pos plas. 1 11 28.6 ± 0.8 12 ± 0 -96.0
1.1.09.01. Sodium-potassium pump, E2P state, conformation 2 3n23 Sus scrofa Eukaryo. plasma 3 12 29.9 ± 0.9 6 ± 0 -96.0
1.1.10.04. P-glycoprotein, inward-facing conformation 6 5kpi Mus musculus Eukaryo. plasma 1 12 31.8 ± 1.6 1 ± 1 -95.8
1.1.16.01. Glutamate receptor 2, with conotoxin, structure 2 4u5c Rattus norvegicus Eukaryo. plasma 4 12 31.4 ± 1.1 1 ± 1 -95.7
1.1.11.01. Protein translocase SecY, mutant with full-plug (TM2a) deletion 2yxr Methanococcus jannaschii Archaebac. 3 12 29.7 ± 0.8 4 ± 4 -95.6
1.1.09.01. Proton-potassium pump, antagonist-bound 4ux2 Sus scrofa Eukaryo. plasma 2 11 32.0 ± 0.5 8 ± 1 -95.5
1.1.09.01. Sodium-potassium pump, E2P state, conformation 3 3kdp Sus scrofa Eukaryo. plasma 3 12 31.4 ± 1.4 7 ± 0 -95.3
1.1.12.01. Potassium channel KcsA, 23A opening conformer 3f7v Streptomyces lividans Bact. Gram-pos plas. 4 8 30.1 ± 1.1 0 ± 0 -95.2
1.1.25.06. Glucose transporter GLUT3/SLC2A3, outward-occluded 4zw9 Homo sapiens Eukaryo. plasma 1 12 32.8 ± 1.4 6 ± 1 -95.1
1.1.12.03. Multi-ligand gated K(+) channel, TrkA 4gx5 Geobacter sulfurreducens Bact. Gram-neg inner 4 8 31.6 ± 0.7 0 ± 0 -94.6
1.1.09.01. Sodium-potassium pump, E2 state 4xe5 Bos taurus Eukaryo. plasma 3 12 29.6 ± 0.5 8 ± 0 -94.2
1.1.25.07. Nitrate/nitrite exchanger NarK, inward-open state 4u4t Escherichia coli Bact. Gram-neg inner 1 12 31.2 ± 1.1 5 ± 1 -94.2
1.1.01.04. Smoothened homolog, dimer, structure 2 4qin Homo sapiens Eukaryo. plasma 2 14 31.6 ± 1.3 1 ± 1 -94.0
1.1.10.02. Maltose transporter MalFGK, outward conformation 3puw Escherichia coli Bact. Gram-neg inner 2 14 29.8 ± 1.3 3 ± 1 -94.0
1.1.11.01. Protein translocase SecY, partialy open 3mp7 Pyrococcus furiosus Archaebac. 2 10 30.1 ± 1.0 5 ± 6 -94.0
1.1.52.02. 4-amino-4-deoxy-L-arabinose transferase 5f15 Cupriavidus metallidurans Bact. Gram-neg inner 1 13 29.2 ± 0.7 3 ± 0 -93.8
1.1.28.03. SecDF protein-export membrane protein 3aqp Thermus thermophilus Bact. Gram-neg inner 1 12 29.8 ± 0.9 5 ± 1 -93.8
1.2.11.01. Capsid protein G8P 1ifl Bacteriophage IKe Secreted 10 10 30.8 ± 0.8 0 ± 0 -93.6
1.1.09.01. Sodium-potassium pump, E2P state, conformation 1 3b8e Sus scrofa Eukaryo. plasma 3 12 30.7 ± 0.9 12 ± 0 -93.6
1.1.80.01. UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase 5lev Homo sapiens Endoplasm. reticulum 1 10 31.8 ± 1.0 5 ± 0 -93.5
1.1.11.01. Protein translocase SecY, closed state, mutant 1rh5 Methanococcus jannaschii Archaebac. 3 12 29.0 ± 1.1 10 ± 0 -93.4
1.1.25.06. Glucose transporter GLUT3/SLC2A3, outward-open 4zwc Homo sapiens Eukaryo. plasma 1 12 33.0 ± 1.3 6 ± 1 -93.2
1.1.16.01. Glutamate receptor 2, with partial agonist, structure 2 4u1y Rattus norvegicus Eukaryo. plasma 4 12 30.6 ± 1.3 6 ± 2 -93.2
1.1.12.06. Potassium channel subfamily K member 4, structure 1 3um7 Homo sapiens Eukaryo. plasma 2 8 30.8 ± 1.2 3 ± 0 -93.2
1.1.38.01. H+-driven MATE exporter, outward-open, "bent" conformation 3vvo Pyrococcus furiosus Archaebac. 1 12 31.4 ± 1.1 11 ± 0 -93.1
1.1.38.01. Multidrug transporter MatE 4z3n Escherichia coli Bact. Gram-neg inner 1 12 29.6 ± 1.1 7 ± 1 -93.1
1.1.10.07. Antigen peptide transporter 1 (TAP1) 5u1d Homo sapiens Endoplasm. reticulum 2 12 30.6 ± 0.4 9 ± 1 -93.0
1.1.16.01. Glutamate receptor 2, with antagonist, structure 1 3kg2 Rattus norvegicus Eukaryo. plasma 4 12 31.8 ± 2.0 0 ± 0 -93.0
1.1.16.01. Glutamate receptor 2, with partial agonist, structure 3 4u1w Rattus norvegicus Eukaryo. plasma 4 12 30.8 ± 0.9 1 ± 0 -92.7
1.1.15.02. Proton-gated ion channel, inactive conformation 2 3uq7 Erwinia chrysanthemi Bact. Gram-neg inner 5 20 32.0 ± 1.6 0 ± 1 -92.6
1.1.10.03. ABC transporter related protein 4mrs Novosphingobium aromaticivorans Bact. Gram-neg inner 2 12 32.0 ± 1.0 0 ± 0 -92.5
1.1.25.01. Glycerol-3-phosphate transporter glpT 1pw4 Escherichia coli Bact. Gram-neg inner 1 12 31.2 ± 1.4 1 ± 7 -92.5
1.1.15.01. Glycine receptor, alpha-1, strychnine-bound state 3jad Danio rerio Eukaryo. plasma 5 20 30.8 ± 1.0 0 ± 0 -92.4
1.1.21.01. Magnesium transport protein CorA 4ev6 Methanococcus jannaschii Archaebac. 5 10 28.4 ± 1.5 0 ± 1 -92.4
1.1.64.01. H+/Ca2+ exchanger 4kpp Archaeoglobus fulgidus Archaebac. 1 12 29.8 ± 1.4 5 ± 0 -92.3
1.1.08.01. F1F0 ATP synthase, F0F1 complex 5fl7 Yarrowia lipolytica Mitochon. inner 10 20 38.0 ± 0.6 0 ± 0 -92.3
1.1.26.05. Amino acid transporter ApcT, inward-facing conformation 3gia Methanococcus jannaschii Archaebac. 1 12 29.9 ± 1.4 11 ± 2 -92.1
1.1.15.01. Glycine receptor, alpha-1 2m6i Homo sapiens Eukaryo. plasma 5 20 26.8 ± 0.3 0 ± 0 -92.1
1.1.10.04. P-glycoprotein, inward-facing conformation 2a 4ksb Mus musculus Eukaryo. plasma 1 12 29.8 ± 1.3 5 ± 0 -91.7
1.1.10.02. Molybdate transporter ModBC, open state 3d31 Methanosarcina acetivorans Archaebac. 2 12 29.8 ± 1.5 1 ± 0 -91.6
1.1.16.01. Glutamate receptor 2, with conotoxin, structure 1 4u5b Rattus norvegicus Eukaryo. plasma 4 12 31.6 ± 1.1 0 ± 0 -91.5
1.1.16.01. Glutamate receptor 2, apo state, structure 1 4u2p Rattus norvegicus Eukaryo. plasma 4 12 31.8 ± 0.8 4 ± 3 -91.4
1.1.09.01. Proton-potassium pump 2xzb Sus scrofa Eukaryo. plasma 2 11 29.7 ± 1.2 9 ± 0 -91.4
1.1.25.07. Nitrate/nitrite exchanger NarK, occluded state 4u4w Escherichia coli Bact. Gram-neg inner 1 12 30.0 ± 1.4 10 ± 1 -91.0
1.1.10.04. P-glycoprotein, inward-facing conformation 2c 4ksd Mus musculus Eukaryo. plasma 1 12 29.6 ± 0.8 5 ± 0 -91.0
1.1.12.01. NaK potassium channel, different strain of Bacillus cereus 3ouf Bacillus cereus Bact. Gram-pos plas. 4 8 27.9 ± 1.3 0 ± 0 -91.0
1.1.10.06. Cystic fibrosis transmembrane conductance regulator 5u71 Homo sapiens Endosome 1 12 31.4 ± 0.6 8 ± 0 -90.7
1.1.26.01. Sodium-dependent serotonin transporter, outward-facing state 5i6x Homo sapiens Eukaryo. plasma 1 12 31.6 ± 1.4 10 ± 0 -90.7
1.1.10.04. P-glycoprotein, inward-facing conformation 1c 4m1m Mus musculus Eukaryo. plasma 1 12 31.2 ± 1.3 2 ± 1 -90.6
1.1.11.01. Protein translocase SecY, complex with ribosome 3 1vvk Methanococcus jannaschii Archaebac. 3 12 28.6 ± 0.7 10 ± 0 -90.3
1.1.25.06. D-xylose-proton symporter xylE, conformation 1 4gc0 Escherichia coli Bact. Gram-neg inner 1 12 30.2 ± 0.9 1 ± 0 -90.2
1.1.12.01. Potassium channel KcsA, structure 2 4uuj Streptomyces lividans Bact. Gram-pos plas. 4 8 29.8 ± 0.5 0 ± 0 -90.2
1.1.25.05. Bacterial proton:oligopeptide symporter, structure 3 4tpj Shewanella oneidensis Bact. Gram-neg inner 1 14 30.6 ± 0.9 9 ± 0 -90.0
1.1.09.01. Sodium-potassium pump, E2P state, conformation 4 4res Sus scrofa Endoplasm. reticulum 3 12 30.0 ± 0.9 7 ± 1 -90.0
1.1.12.01. NaK potassium channel, open state 3e86 Bacillus cereus Bact. Gram-pos plas. 4 8 27.6 ± 0.9 0 ± 0 -90.0
1.1.08.01. F1F0 ATP synthase, F0 complex 4f4s Saccharomyces cerevisiae Mitochon. inner 10 20 38.4 ± 1.3 0 ± 0 -89.9
1.1.25.06. Glucose transporter GLUT5, inward-open 4yb9 Bos taurus Eukaryo. plasma 1 12 31.8 ± 1.0 6 ± 0 -89.9
1.1.04.01. Respiratory complex I 4wz7 Yarrowia lipolytica Mitochon. inner 22 84 29.8 ± 0.1 6 ± 0 -89.8
1.1.83.01. Bacterial translocator protein, dimer 4ryi Bacillus cereus Bact. Gram-pos plas. 2 10 30.4 ± 1.2 2 ± 0 -89.7
1.3.16.01. Porin B (PorB) 4aui Neisseria gonorrhoeae Bact. Gram-neg outer 3 48 24.2 ± 0.8 0 ± 0 -89.7
1.1.52.01. Oligosaccharyltransferase PglB 3rce Campylobacter lari Bact. Gram-neg inner 1 13 28.8 ± 0.9 8 ± 0 -89.6
1.1.25.02. Lactose permease LacY, structure 6 5gxb Escherichia coli Bact. Gram-neg inner 1 12 33.8 ± 1.5 1 ± 1 -89.6
1.1.96.01. Fluoride ion transporter CrcB 5a43 Escherichia coli Bact. Gram-neg inner 2 8 31.8 ± 0.9 11 ± 0 -89.3
1.1.11.01. Protein translocase SecY, closed state 1rhz Methanococcus jannaschii Archaebac. 3 12 29.4 ± 1.0 5 ± 0 -89.2
1.1.25.09. Iron-regulated transporter, inward-facing state 5ayo Bdellovibrio bacteriovorus Bact. Gram-neg inner 1 12 31.6 ± 0.7 7 ± 1 -89.2
1.1.12.02. Potassium channel Kirbac3.1, open conformation 2 4lp8 Magnetospirillum magnetotacticum Bact. Gram-neg inner 4 8 29.2 ± 0.8 0 ± 0 -89.2
1.1.10.04. P-glycoprotein, inward-facing conformation 2b 4ksc Mus musculus Eukaryo. plasma 1 12 30.0 ± 1.5 4 ± 1 -89.2
1.1.26.01. Leucine transporter LeuT, inward-facing conformation 3tt3 Aquifex aeolicus Bact. Gram-neg inner 1 12 27.4 ± 1.6 9 ± 0 -89.1
1.1.25.05. Bacterial proton:oligopeptide symporter, structure 1 4lep Shewanella oneidensis Bact. Gram-neg inner 1 14 29.4 ± 0.6 7 ± 0 -89.1
1.1.25.02. Lactose permease LacY, structure 3 1pv6 Escherichia coli Bact. Gram-neg inner 1 12 31.8 ± 1.2 5 ± 0 -89.1
1.1.11.01. Protein translocase SecY, mutant with half-plug (TM2a) deletion 2yxq Methanococcus jannaschii Archaebac. 3 12 29.2 ± 1.1 6 ± 0 -89.1
1.1.25.02. Lactose permease LacY, structure 4 2y5y Escherichia coli Bact. Gram-neg inner 1 12 31.8 ± 1.3 4 ± 1 -89.0
1.1.01.02. C-C chemokine receptor type 5 4mbs Homo sapiens Eukaryo. plasma 1 7 34.4 ± 1.5 0 ± 0 -88.8
1.1.12.02. Kir3.1-prokaryotic Kir channel chimera 2qks Burkholderia xenovorans Bact. Gram-neg inner 4 8 30.5 ± 1.4 0 ± 1 -88.6
1.1.38.01. H+-driven MATE exporter, outward-open, straight conformation 3wbn Pyrococcus furiosus Archaebac. 1 12 31.8 ± 1.4 8 ± 0 -88.2
1.1.25.07. Nitrite exporter NarU 4iu9 Escherichia coli Bact. Gram-neg inner 1 12 31.0 ± 1.2 4 ± 0 -88.1
1.1.38.01. H+-driven MATE exporter, outward-open, different conformation 4mlb Pyrococcus furiosus Archaebac. 1 12 30.2 ± 1.2 5 ± 0 -88.1
1.1.25.02. Lactose permease LacY, structure 1 2cfq Escherichia coli Bact. Gram-neg inner 1 12 31.9 ± 1.1 5 ± 1 -87.9
1.1.25.06. D-xylose-proton symporter xylE, conformation 2 4ja3 Escherichia coli Bact. Gram-neg inner 1 12 29.8 ± 1.0 4 ± 1 -87.6
1.1.61.01. Microsomal prostaglandin E synthase 1, structure 2 4bpm Homo sapiens Endoplasm. reticulum 3 12 31.6 ± 1.4 0 ± 3 -87.5
1.1.64.01. Vacuolar calcium ion transporter 4k1c Saccharomyces cerevisiae Vacuole 1 11 29.8 ± 1.0 3 ± 0 -87.5
1.1.01.01. Sodium pumping rhodopsin, NaR, dimer 3x3b Dokdonia eikasta Bact. Gram-neg inner 2 14 29.8 ± 0.9 0 ± 0 -87.5
1.1.16.01. Glutamate receptor 2, with antagonist, structure 2 4uqj Rattus norvegicus Eukaryo. plasma 4 12 33.6 ± 1.6 0 ± 0 -87.3
1.1.12.01. Potassium channel KcsA, full length, open 3pjs Streptomyces lividans Bact. Gram-pos plas. 4 8 31.6 ± 1.2 1 ± 1 -87.3
1.1.25.06. Bicyclomycin resistance protein TcaB 4lds Staphylococcus epidermidis Bact. Gram-pos plas. 1 12 31.8 ± 1.6 4 ± 0 -87.1
1.1.26.01. MhsT transporter, inward-facing state 4us3 Bacillus halodurans Bact. Gram-pos plas. 1 11 29.8 ± 0.8 11 ± 1 -87.1
1.1.77.01. Cellulose synthase, structure 4 5ejz Rhodobacter sphaeroides Bact. Gram-neg inner 1 8 29.6 ± 1.1 18 ± 0 -86.9
1.1.25.02. Lactose permease LacY, structure 2 2v8n Escherichia coli Bact. Gram-neg inner 1 12 31.8 ± 0.8 5 ± 0 -86.4
1.1.11.01. Ribosome-SecYE complex, structure 1 3j01 Escherichia coli Bact. Gram-neg inner 2 13 28.6 ± 0.0 5 ± 0 -86.4
1.1.84.01. Bifunctional IPC transferase and DIPP synthase 4mnd Archaeoglobus fulgidus Archaebac. 2 12 30.2 ± 1.0 0 ± 0 -86.4
1.1.25.07. Nitrate/nitrite exchanger NarK, partially occluded state 4jr9 Escherichia coli Bact. Gram-neg inner 1 12 29.6 ± 1.0 8 ± 0 -86.2
1.1.12.01. Potassium channel KcsA, 16 A opening conformer 3fb6 Streptomyces lividans Bact. Gram-pos plas. 4 8 30.2 ± 1.0 0 ± 0 -86.1
1.1.40.01. Glutamate-dependent intramembrane protease Rce1 4cad Saccharomyces cerevisiae Endoplasm. reticulum 1 8 30.8 ± 1.3 0 ± 1 -86.1
1.1.12.02. Potassium channel Kirbac3.1, open conformation 3zrs Magnetospirillum magnetotacticum Bact. Gram-neg inner 4 8 30.0 ± 1.1 0 ± 0 -85.9
1.1.09.01. Sodium-potassium pump, E2P state, conformation 5 2yn9 Sus scrofa Eukaryo. plasma 2 11 30.6 ± 0.8 10 ± 0 -85.9
1.2.43.01. Capsid envelop protein complex, Zika, structure 3 5h37 Zika virus Vesicle 6 12 25.8 ± 0.0 2 ± 0 -85.7
1.1.11.01. Protein translocase Sec61, complex with ribosome, active state 2ww9 Saccharomyces cerevisiae Endoplasm. reticulum 3 12 29.7 ± 1.7 5 ± 0 -85.5
1.1.10.01. Heme importer BhuUV 5b57 Burkholderia cepacia Bact. Gram-neg inner 2 20 28.6 ± 0.8 1 ± 1 -85.4
1.1.25.02. Lactose permease lacY, structure at acidic pH 2cfp Escherichia coli Bact. Gram-neg inner 1 12 31.1 ± 1.4 2 ± 2 -85.4
1.1.10.04. P-glycoprotein, inward-facing conformation 1b 4lsg Mus musculus Eukaryo. plasma 1 12 31.0 ± 8.0 2 ± 0 -85.3
1.3.28.01. LPS-assembly protein complex, LptE and LptD 4rhb Escherichia coli Bact. Gram-neg outer 2 26 23.4 ± 1.1 7 ± 0 -85.3
1.1.25.04. L-fucose-proton symporter fucP 3o7q Escherichia coli Bact. Gram-neg inner 1 12 30.7 ± 1.3 6 ± 0 -85.3
1.1.41.01. Magnesium ion transporter-E (MgtE), structure 2 4u9n Thermus thermophilus Bact. Gram-neg inner 2 10 31.8 ± 0.8 0 ± 0 -85.3
1.1.61.01. Microsomal prostaglandin E synthase 1, structure 3 4yl3 Homo sapiens Endoplasm. reticulum 3 12 29.8 ± 0.7 0 ± 0 -85.2
1.1.26.02. Sodium-hydantoin transporter Mhp1, inward-facing conformation 2x79 Mycobacterium liquefaciens Bact. Gram-pos plas. 1 12 30.7 ± 1.1 13 ± 0 -85.0
1.1.77.01. Cellulose synthase, structure 1 4hg6 Rhodobacter sphaeroides Bact. Gram-neg inner 2 9 30.0 ± 1.3 17 ± 0 -85.0
1.1.16.01. Glutamate receptor 2, with conotoxin, structure 3 4u5f Rattus norvegicus Eukaryo. plasma 4 12 31.8 ± 1.1 2 ± 1 -84.9
1.3.29.01. Bacterial amyloid secretion channel CsgG, structure 2 4uv3 Escherichia coli Bact. Gram-neg outer 9 36 26.4 ± 0.9 0 ± 0 -84.6
1.1.10.02. Methionine importer MetNI, conformation 2 3tuj Escherichia coli Bact. Gram-neg inner 2 10 30.4 ± 1.3 7 ± 1 -84.5
1.1.08.01. F1F0 ATP synthase, F0 complex 3zk1 Fusobacterium nucleatum Bact. Gram-neg inner 11 22 36.6 ± 2.3 0 ± 0 -84.3
1.1.25.05. Nitrate transporter NRT1/ PTR, structure 2 5a2n Arabidopsis thaliana Eukaryo. plasma 1 12 31.8 ± 1.3 7 ± 1 -84.3
1.3.20.01. Fe(III)-pyochelin receptor FptA 1xkw Pseudomonas aeruginosa Bact. Gram-neg outer 1 22 24.8 ± 1.0 5 ± 4 -84.3
1.1.25.06. Phosphate transporter 4j05 Acanthamoeba culbertsoni Eukaryo. plasma 1 12 30.0 ± 0.5 14 ± 0 -84.2
1.1.27.01. Ferrous-iron efflux pump fieF 3h90 Escherichia coli Bact. Gram-neg inner 2 12 29.6 ± 0.8 0 ± 2 -83.9
1.1.12.01. Potassium channel KcsA, open inactivated state 3f5w Streptomyces lividans Bact. Gram-pos plas. 4 8 29.2 ± 0.7 0 ± 0 -83.5
1.1.10.03. ATP-binding cassette, sub-family B, member 1 3wme Cyanidoschyzon merolae Eukaryo. plasma 2 12 35.0 ± 1.6 0 ± 0 -83.5
1.2.11.01. Capsid protein G8P 1ifk Bacteriophage If1 Secreted 15 15 31.8 ± 0.7 0 ± 0 -83.5
1.1.21.01. CorA magnesium transporter, complete loops, structure 1 4i0u Thermotoga maritima Bact. Gram-neg inner 5 10 30.4 ± 1.1 0 ± 0 -83.4
1.1.01.02. Opioid mu receptor, active state 5c1m Mus musculus Eukaryo. plasma 1 7 34.4 ± 2.9 9 ± 0 -83.2
1.1.25.09. Iron-regulated transporter, outward-facing state 5ayn Bdellovibrio bacteriovorus Bact. Gram-neg inner 1 12 29.8 ± 1.8 8 ± 4 -82.9
1.1.25.06. D-xylose-proton symporter xylE, conformation 3 4ja4 Escherichia coli Bact. Gram-neg inner 1 12 28.2 ± 1.3 0 ± 0 -82.8
1.3.25.03. Hemolytic lectin CEL-III 3w9t Cucumaria echinata (Sea cucumber) Secreted 7 14 33.8 ± 0.8 0 ± 0 -82.6
1.1.10.02. Methionine importer MetNI, conformation 3 3dhw Escherichia coli Bact. Gram-neg inner 2 10 29.2 ± 1.0 1 ± 0 -82.5
1.1.77.01. Cellulose synthase, structure 3 4p02 Rhodobacter sphaeroides Bact. Gram-neg inner 2 9 29.8 ± 1.2 18 ± 1 -82.5
1.1.72.01. Dicarboxylate/sodium symporter NadC 4f35 Vibrio cholerae Bact. Gram-neg inner 2 28 27.8 ± 0.2 1 ± 0 -82.5
1.3.29.01. Bacterial amyloid secretion channel CsgG, structure 1 4q79 Escherichia coli Bact. Gram-neg outer 9 36 25.6 ± 0.6 0 ± 0 -82.4
1.1.07.01. Ubiquinol Oxidase 1fft Escherichia coli Bact. Gram-neg inner 3 19 29.5 ± 0.6 12 ± 0 -82.3
1.1.33.01. Bile acid sodium symporter ASBT, inward-open conformation 3zuy Neisseria meningitidis Bact. Gram-neg inner 1 10 29.8 ± 1.5 15 ± 2 -82.3
1.1.12.01. Potassium channel KcsA, 17A opening conformer 3f7y Streptomyces lividans Bact. Gram-pos plas. 4 8 31.3 ± 1.3 0 ± 0 -82.3
1.1.98.01. Polyisoprenyl-phosphate glycosyltransferase GtrB 5eke Synechocystis sp. Bact. Gram-neg inner 4 8 31.4 ± 1.2 0 ± 0 -82.3
1.1.02.06. Photoprotective protein PsbS 4ri2 Spinacia oleracea Thylakoid 2 8 29.8 ± 0.9 0 ± 0 -82.2
1.1.77.01. Cellulose synthase, structure 2 4p00 Rhodobacter sphaeroides Bact. Gram-neg inner 2 9 27.6 ± 1.2 19 ± 0 -82.0
1.3.28.01. LPS-assembly protein complex, LptE and LptD 5ixm Yersinia pestis Bact. Gram-neg outer 1 26 22.8 ± 0.9 6 ± 1 -81.9
1.1.16.01. Glutamate receptor ionotropic, kainate 2 5kuf Rattus norvegicus Eukaryo. plasma 4 12 31.4 ± 0.6 0 ± 0 -81.8
1.1.25.03. Transporter YajR 3wdo Escherichia coli Bact. Gram-neg inner 1 12 31.0 ± 1.4 2 ± 0 -81.8
1.1.11.01. Protein translocase Sec61, structure 4 5a6u Canis lupus familiaris Endoplasm. reticulum 3 12 29.8 ± 0.7 4 ± 1 -81.8
1.1.10.06. Cystic fibrosis transmembrane conductance regulator 5tsi Danio rerio Endosome 1 12 30.6 ± 0.8 0 ± 0 -81.7
1.1.11.01. Ribosome-SecYE complex, structure 4 3kcr Escherichia coli Bact. Gram-neg inner 3 12 29.2 ± 0.6 13 ± 0 -81.6
1.1.10.01. Heme importer BhuUV, with BhuT protein 5b58 Burkholderia cepacia Bact. Gram-neg inner 2 20 29.0 ± 1.0 0 ± 0 -81.6
1.1.21.01. CorA magnesium transporter, structure 2 4eeb Thermotoga maritima Bact. Gram-neg inner 5 10 30.0 ± 1.0 1 ± 1 -81.6
1.1.01.02. Endothelin B receptor, with endothelin 5glh Homo sapiens Eukaryo. plasma 1 7 34.8 ± 1.0 6 ± 1 -81.5
1.1.91.01. Delta(14)-sterol reductase 4quv Methylomicrobium alcaliphilum Bact. Gram-neg inner 1 10 28.2 ± 1.4 11 ± 3 -81.4
1.1.13.02. P2X purinoceptor 3, open state 5svk Homo sapiens Eukaryo. plasma 3 6 31.6 ± 0.8 0 ± 0 -81.4
1.3.20.01. Ferric hydroxamate uptake receptor FhuA 1qfg Escherichia coli Bact. Gram-neg outer 1 22 24.7 ± 1.0 5 ± 1 -81.3
1.3.28.01. LPS-assembly protein complex, LptE and LptD 5iv9 Klebsiella pneumoniae Bact. Gram-neg outer 1 26 23.4 ± 1.0 3 ± 0 -81.0
1.1.10.02. Methionine importer MetNI, conformation 1 3tui Escherichia coli Bact. Gram-neg inner 2 10 30.2 ± 1.3 1 ± 1 -81.0
1.1.11.01. Protein translocase SecY, complex with ribosome 1 3dkn Methanococcus jannaschii Archaebac. 3 12 27.8 ± 1.8 2 ± 0 -80.9
1.1.21.01. CorA magnesium transporter, structure 1 2bbj Thermotoga maritima Bact. Gram-neg inner 5 10 29.9 ± 1.0 0 ± 0 -80.8
1.1.26.01. Leucine transporter LeuT, outward-facing, return state, mutant 5jag Aquifex aeolicus Bact. Gram-neg inner 1 12 26.8 ± 1.1 11 ± 0 -80.7
1.3.28.01. LPS-assembly protein complex, LptE and LptD 4n4r Salmonella typhimurium Bact. Gram-neg outer 1 26 23.4 ± 1.5 4 ± 0 -80.4
1.1.21.01. CorA magnesium transporter, complete loops, structure 3 5jrw Thermotoga maritima Bact. Gram-neg inner 5 10 31.0 ± 0.6 0 ± 0 -80.2
1.1.01.02. C-C chemokine receptor type 2 5t1a Homo sapiens Eukaryo. plasma 1 7 32.6 ± 1.4 3 ± 2 -80.2
1.1.01.02. Opsin, complex with arrestin peptide 4pxf Bos taurus Eukaryo. plasma 1 7 31.6 ± 0.9 8 ± 1 -80.1
1.1.70.01. CAAX prenyl protease 1 homolog, structure 1 5syt Homo sapiens Endoplasm. reticulum 1 7 31.4 ± 1.4 15 ± 0 -79.9
1.1.11.01. Protein translocase Sec61, structure 2 4cg6 Canis lupus familiaris Endoplasm. reticulum 4 13 28.8 ± 1.2 7 ± 1 -79.9
1.1.01.02. P2Y purinoceptor 12, structure 1 4ntj Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 9 ± 0 -79.8
1.2.50.01. Fragaceatoxin C, transmembrane octamer 4tsy Actinia fragacea (Strawberry anemone) Secreted 8 8 29.8 ± 1.3 0 ± 0 -79.7
1.1.33.01. Sodium bile acid symporter, outward-open conformation 1 4n7x Yersinia frederiksenii Bact. Gram-neg inner 1 10 28.6 ± 1.0 12 ± 0 -79.7
1.1.01.02. C-X-C chemokine receptor type 4, inactive, complex with antagonist 3oe6 Homo sapiens Eukaryo. plasma 1 7 35.3 ± 2.5 8 ± 7 -79.7
1.1.10.03. Mitochondrial ABC transporter ABCB10, conformation 1 4ayt Homo sapiens Mitochon. inner 2 12 30.4 ± 0.8 0 ± 0 -79.7
1.3.20.01. Pyoverdine Outer Membrane Receptor FpvA 2iah Pseudomonas aeruginosa Bact. Gram-neg outer 1 22 24.0 ± 0.5 8 ± 0 -79.7
1.1.38.01. H+-driven MATE exporter, outward-open, with nonpeptide inhibitor 3vvp Pyrococcus furiosus Archaebac. 1 12 29.8 ± 1.3 8 ± 0 -79.6
1.1.01.02. P2Y purinoceptor 12, structure 2 4pxz Homo sapiens Eukaryo. plasma 1 7 36.0 ± 1.9 4 ± 3 -79.5
1.1.11.01. SecA-SecY complex 5eul Bacillus subtilis Bact. Gram-pos plas. 3 12 27.0 ± 1.2 7 ± 1 -79.5
1.1.16.01. Glutamate receptor 2, with partial agonist, structure 1 4u1x Rattus norvegicus Eukaryo. plasma 4 12 29.8 ± 0.8 0 ± 0 -79.3
1.1.26.06. Uracil transporter UraA 3qe7 Escherichia coli Bact. Gram-neg inner 1 14 27.7 ± 1.2 16 ± 0 -79.3
1.1.01.06. Adiponectin receptor 1, closed 3wxv Homo sapiens Eukaryo. plasma 1 7 32.8 ± 1.2 15 ± 1 -79.3
1.1.83.01. TspO protein, structure 2 4uc2 Rhodobacter sphaeroides Bact. Gram-neg outer 2 10 30.4 ± 0.9 1 ± 0 -79.2
1.1.16.01. Glutamate receptor 2, with partial agonist, structure 6 4u4g Rattus norvegicus Eukaryo. plasma 4 12 33.0 ± 1.6 0 ± 0 -79.1
1.1.01.02. Rhodopsin, partially active, photobleached 2i37 Bos taurus Eukaryo. plasma 1 7 31.9 ± 1.5 5 ± 1 -79.1
1.1.12.01. Potassium channel KcsA, complex with Rb+ 3fb7 Streptomyces lividans Bact. Gram-pos plas. 4 8 28.6 ± 1.2 0 ± 0 -79.0
1.1.10.07. Heterodimeric ABC transporter TmrAB 5mkk Thermus thermophilus Bact. Gram-neg inner 2 12 31.0 ± 0.6 5 ± 0 -78.8
1.1.12.02. Potassium channel Kirbac3.1, closed conformation 2wlk Magnetospirillum magnetotacticum Bact. Gram-neg inner 4 8 29.8 ± 2.4 0 ± 0 -78.7
1.1.01.02. Rhodopsin, complex with arrestin 4zwj Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.1 9 ± 1 -78.7
1.1.35.01. Sodium/proton antiporter 1 (NhaA) 1zcd Escherichia coli Bact. Gram-neg inner 1 14 28.4 ± 1.4 2 ± 2 -78.6
1.1.12.01. Potassium channel KvAP, complex with Fab 1orq Aeropyrum pernix Archaebac. 4 12 29.3 ± 1.6 0 ± 0 -78.6
1.3.20.01. SusD-SusC complex 5t3r Bacteroides thetaiotaomicron Bact. Gram-neg outer 1 22 25.0 ± 0.6 3 ± 0 -78.5
1.1.64.01. Sodium/calcium exchanger, structure 1 3v5u Methanococcus jannaschii Archaebac. 1 10 29.8 ± 0.9 3 ± 0 -78.4
1.1.01.02. Rhodopsin, active (metarhodopsin II), complex with peptide of transducin 3pqr Bos taurus Eukaryo. plasma 1 7 31.8 ± 1.1 9 ± 1 -78.3
1.1.26.07. Fumarate transporter 5da0 Deinococcus radiodurans Bact. Gram-neg inner 1 14 26.8 ± 0.7 13 ± 1 -78.2
1.1.16.01. Glutamate receptor 2, with partial agonist, structure 4 4u2q Rattus norvegicus Eukaryo. plasma 4 12 31.6 ± 1.3 6 ± 4 -78.2
1.1.01.02. Muscarinic acetylcholine receptor M1 5cxv Homo sapiens Eukaryo. plasma 1 7 32.8 ± 0.7 4 ± 0 -78.2
1.1.29.01. YddG transporter 5i20 Starkeya novella Bact. Gram-neg inner 1 10 30.2 ± 1.3 0 ± 0 -78.1
1.1.01.06. Adiponectin receptor 2 5lwy Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.4 16 ± 0 -78.0
1.1.21.01. CorA magnesium transporter, complete loops, structure 2 3jcf Thermotoga maritima Bact. Gram-neg inner 5 10 31.6 ± 0.7 0 ± 0 -78.0
1.1.01.02. Type-2 angiotensin II receptor, structure 2 5ung Homo sapiens Eukaryo. plasma 1 7 32.6 ± 0.8 6 ± 0 -78.0
1.1.01.02. Muscarinic acetylcholine receptor M4 5dsg Homo sapiens Eukaryo. plasma 1 7 34.6 ± 2.1 10 ± 1 -78.0
1.1.11.01. Protein translocase SecY, complex with ribosome 2 3bo0 Methanococcus jannaschii Archaebac. 3 12 29.6 ± 1.2 6 ± 2 -78.0
1.1.01.02. Beta-1 adrenergic receptor, inactive, complex with antagonist 2ycw Meleagris gallopavo Eukaryo. plasma 1 7 32.2 ± 1.3 2 ± 0 -77.8
1.3.20.01. Ferric hydroxamate uptake receptor FhuA, with microcin 4cu4 Escherichia coli Bact. Gram-neg outer 1 22 24.6 ± 1.1 5 ± 0 -77.7
1.1.90.01. Phosphatidate cytidylyltransferase, conformation 1 4q2e Thermotoga maritima Bact. Gram-neg inner 2 18 29.8 ± 0.6 1 ± 0 -77.7
1.1.01.02. Endothelin B receptor 5gli Homo sapiens Eukaryo. plasma 1 7 33.6 ± 1.4 11 ± 0 -77.6
1.3.20.01. Outer membrane receptor FauA 3efm Bordetella pertussis Bact. Gram-neg outer 1 22 24.7 ± 0.6 11 ± 0 -77.5
1.3.20.01. Outer membrane cobalamin transporter BtuB, complex with TonB 2gsk Escherichia coli Bact. Gram-neg outer 1 22 23.4 ± 0.7 5 ± 0 -77.5
1.1.01.02. 5-hydroxytryptamine receptor 1B, conformation 2 4iaq Homo sapiens Eukaryo. plasma 1 7 34.4 ± 1.7 6 ± 1 -77.4
1.1.11.01. Protein translocase Sec61, complex with ribosome 4w25 Sus scrofa Endoplasm. reticulum 3 12 28.6 ± 1.1 4 ± 0 -77.3
1.1.25.03. Multidrug transporter MdfA 4zp0 Escherichia coli Bact. Gram-neg inner 1 12 29.8 ± 1.3 10 ± 0 -77.2
1.3.12.01. Outer membrane phospholipase A, dimer 1qd6 Escherichia coli Bact. Gram-neg outer 2 24 23.9 ± 1.0 0 ± 0 -77.2
1.3.20.01. Ferric enterobactin receptor FepA 1fep Escherichia coli Bact. Gram-neg outer 1 22 24.3 ± 1.1 1 ± 0 -77.2
1.3.20.01. Ferric hydroxamate uptake receptor FhuA, complex with TonB 2grx Escherichia coli Bact. Gram-neg outer 1 22 24.6 ± 1.1 3 ± 0 -77.2
1.1.12.01. Calcium-activated cation channel 5cbg Tsukamurella paurometabola Bact. Gram-pos plas. 4 14 31.6 ± 0.8 0 ± 0 -77.0
1.1.01.02. Beta-1 adrenergic receptor, inactive, complex with agonist 2y02 Meleagris gallopavo Eukaryo. plasma 1 7 31.4 ± 1.3 2 ± 0 -76.9
1.1.01.02. C-X-C chemokine receptor type 4, complex with peptide 4rws Homo sapiens Eukaryo. plasma 1 7 33.8 ± 1.5 9 ± 1 -76.9
1.3.25.04. Protective antigen 3j9c Bacillus anthracis Secreted 7 14 34.6 ± 1.2 0 ± 0 -76.8
1.1.10.03. Mitochondrial ABC transporter ABCB10, conformation 3 4ayx Homo sapiens Mitochon. inner 2 12 30.0 ± 0.6 0 ± 0 -76.8
1.2.58.01. Sigma intracellular receptor 1, structure 2 5hk2 Homo sapiens Endoplasm. reticulum 3 3 32.4 ± 1.4 19 ± 0 -76.6
1.1.25.05. Nitrate transporter NRT1/ PTR, structure 1 4cl4 Arabidopsis thaliana Eukaryo. plasma 1 12 31.6 ± 1.6 7 ± 0 -76.5
1.3.28.01. LPS-assembly protein complex, LptE and LptD 5iva Pseudomonas aeruginosa Bact. Gram-neg outer 1 26 23.2 ± 0.7 4 ± 0 -76.4
1.1.01.02. 5-hydroxytryptamine receptor 1B, conformation 1 4iar Homo sapiens Eukaryo. plasma 1 7 33.6 ± 1.8 7 ± 1 -76.4
1.1.39.03. Energy-coupling factor transporter EcfA, conformation 2 4huq Lactobacillus brevis Bact. Gram-pos plas. 2 7 29.8 ± 0.7 14 ± 0 -76.0
1.2.25.01. Phospholamban, pentamer 1zll Homo sapiens Endoplasm. reticulum 5 5 30.5 ± 1.4 0 ± 2 -76.0
1.1.09.01. Calcium ATPase, E2 state (Ca-free), complex with phospholamban 4kyt Oryctolagus cuniculus Endoplasm. reticulum 3 12 28.0 ± 0.6 27 ± 0 -75.9
1.1.01.02. Type-2 angiotensin II receptor, structure 1 5unh Homo sapiens Eukaryo. plasma 1 7 33.0 ± 1.0 7 ± 1 -75.9
1.1.70.01. CAAX prenyl protease 1 homolog, structure 2 4aw6 Homo sapiens Endoplasm. reticulum 1 7 30.8 ± 1.3 13 ± 1 -75.9
1.1.01.02. Muscarinic acetylcholine receptor M3, structure 1 4daj Rattus norvegicus Eukaryo. plasma 1 7 32.2 ± 1.2 5 ± 0 -75.8
1.1.01.02. C-C chemokine receptor type 9 5lwe Homo sapiens Eukaryo. plasma 1 7 33.0 ± 1.8 7 ± 0 -75.8
1.1.01.02. Rhodopsin, inactive, complex with inverse agonist, 11-cis retinal 1gzm Bos taurus Eukaryo. plasma 1 7 32.2 ± 1.5 11 ± 1 -75.6
1.3.20.01. Enantio-pyochelin receptor FetA 3qlb Pseudomonas fluorescens Bact. Gram-neg outer 1 22 23.4 ± 0.8 7 ± 0 -75.3
1.3.20.01. Outer membrane cobalamin transporter BtuB, complex with colicin E2 R-domain 2ysu Escherichia coli Bact. Gram-neg outer 1 22 24.2 ± 1.0 5 ± 0 -75.2
1.1.01.02. Squid rhodopsin, complex with 11-cis retinal 2ziy Todarodes pacificus Eukaryo. plasma 1 7 32.9 ± 1.7 11 ± 2 -75.1
1.1.64.01. Sodium/calcium exchanger, structure 2 3v5s Methanococcus jannaschii Archaebac. 1 10 29.6 ± 1.6 1 ± 2 -75.1
1.1.01.02. Beta-1 adrenergic receptor, mutant with inverse agonist 5a8e Meleagris gallopavo Eukaryo. plasma 1 7 31.8 ± 1.0 9 ± 0 -75.1
1.1.01.02. Neurotensin receptor type 1, structure 1 4grv Rattus norvegicus Eukaryo. plasma 1 7 31.6 ± 1.1 4 ± 1 -75.1
1.2.12.02. Archaeal flagellin 5kyh Ignicoccus hospitalis Archaebac. 4 4 37.4 ± 2.0 18 ± 2 -75.0
1.2.58.01. Sigma intracellular receptor 1, structure 1 5hk1 Homo sapiens Endoplasm. reticulum 3 3 30.8 ± 0.