PDB ID or protein name

All proteins in OPM (3450 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.4.16.02. Termicin 1mm0 Pseudacanthotermes spiniger Secreted 1 0 4.2 ± 0.5 81 ± 3 -3.3
2.2.58.01. Cone arrestin 1suj Ambystoma tigrinum (Tiger salamander) Eukaryo. plasma 1 0 1.4 ± 0.8 82 ± 12 -4.7
2.3.06.06. Lipase B, circular permutation 3icv Candida antarctica Secreted 2 0 8.3 ± 0.8 83 ± 7 -11.3
3.1.30.01. Lactoferricin peptide (36-59) 5id5 Sus scrofa Secreted 1 0 7.4 ± 1.0 87 ± 9 -6.2
2.2.20.01. Spectrin beta chain 1btn Mus musculus Eukaryo. plasma 1 0 13.7 ± 1.6 57 ± 19 -17.3
2.3.16.04. EH domain-containing protein 2 2qpt Mus musculus Endosome 2 0 4.5 ± 2.1 20 ± 14 -7.8
2.2.33.01. Antimicrobial Peptide AMP-1.1a 2kus Stellaria media Secreted 1 0 1.5 ± 0.9 18 ± 27 -2.7
1.2.42.01. UDP-2,3-diacylglucosamine hydrolase, lpxH 5k8k Haemophilus influenzae Bact. Gram-neg inner 1 0 9.3 ± 1.8 13 ± 7 -8.7
2.2.22.01. Hydrophobin I 2gvm Hypocrea jecorina Secreted 1 0 5.3 ± 1.1 27 ± 18 -8.7
2.4.18.01. Phospholipase B-like protein 3fgr Mus musculus Lysosome 2 0 6.5 ± 2.4 79 ± 8 -5.3
1.1.49.01. ATP-dependent zinc metalloprotease FtsH 1lv7 Escherichia coli Bact. Gram-neg inner 1 0 2.1 ± 1.0 80 ± 11 -4.3
2.2.04.01. Retinoid isomerohydrolase, conformation 1 3fsn Bos taurus Eukaryo. plasma 1 0 7.8 ± 1.0 73 ± 10 -10.3
1.2.32.01. Cytochrome P450 3A4, conformation 1 1tqn Homo sapiens Endoplasm. reticulum 1 0 8.7 ± 1.0 67 ± 11 -18.5
2.1.01.01. Myotoxin II 1xxs Bothrops moojeni Secreted 1 0 4.5 ± 1.2 76 ± 10 -5.3
3.2.04.02. Bowman-Birk type proteinase inhibitor peptide 1gm2 Macrotyloma axillare Secreted 1 0 2.0 ± 1.9 59 ± 14 -3.5
1.2.03.02. T-cell immunoglobulin and mucin domain-containing protein 4 5f7h Homo sapiens Eukaryo. plasma 1 0 4.7 ± 2.6 65 ± 5 -6.0
1.2.32.01. Plant cytochrome P450 74A (allene oxide synthase) 3dan Parthenium argentatum Vacuole 1 0 7.5 ± 0.4 64 ± 2 -24.1
3.1.15.03. Bacteriocin peptide plantaricin E (PlnE) 2jui Lactobacillus plantarum Secreted 1 0 4.3 ± 4.2 79 ± 4 -5.0
2.1.24.01. Pore-forming peptide ameobapore A 1of9 Entamoeba histolytica Undefined 1 0 1.5 ± 1.0 13 ± 18 -2.3
2.2.11.01. Extended synaptotagmin-2, third C2 domain 2dmg Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.0 76 ± 5 -4.8
2.2.35.01. Perfringolysin 1pfo Clostridium perfringens Secreted 1 0 4.4 ± 2.0 38 ± 12 -6.7
2.1.60.03. Pseudechetoxin 2dda Pseudechis australis Secreted 1 0 4.5 ± 2.8 89 ± 7 -4.3
2.1.15.01. Epsin-1 1h0a Rattus norvegicus Eukaryo. plasma 1 0 3.2 ± 1.1 39 ± 19 -5.3
2.2.11.01. C2 domain of otoferlin 3l9b Rattus norvegicus Vesicle 1 0 2.4 ± 5.2 16 ± 33 -3.4
2.2.34.02. Mu-agatoxin-Aa1a 1eit Agelenopsis aperta Secreted 1 0 1.3 ± 1.5 59 ± 10 -3.1
2.3.17.02. Dihydropteroate synthase 1tx2 Bacillus anthracis Bact. Gram-pos plas. 2 0 2.5 ± 0.3 90 ± 2 -7.7
2.3.06.09. Mycobacterial lipase 3aja Mycobacterium smegmatis Secreted 1 0 6.0 ± 1.0 28 ± 10 -6.7
2.4.06.03. S-norcoclaurine synthase 2vq5 Thalictrum flavum (Yellow meadow rue) Undefined 4 0 2.6 ± 0.3 90 ± 0 -7.0
2.3.06.01. Neuroligin-4, X-linked, complex with neurexin 1-beta 2xb6 Homo sapiens Eukaryo. plasma 2 0 1.9 ± 3.0 84 ± 11 -3.3
1.2.39.01. Endoplasmic reticulum aminopeptidase 2 3se6 Homo sapiens Endoplasm. reticulum 1 0 2.5 ± 1.8 60 ± 21 -4.5
2.4.16.03. Toxin I5a 1sis Buthus eupeus Secreted 1 0 3.1 ± 1.4 74 ± 16 -4.4
3.4.08.04. Met-enkephalin 1plw Homo sapiens Secreted 1 0 4.9 ± 0.8 85 ± 17 -3.8
2.1.20.01. Prothrombin 1nl2 Bos taurus Eukaryo. plasma 1 0 3.9 ± 3.0 18 ± 24 -5.8
3.1.07.03. Hemagglutinin, peptide 330-349, F9A 2jrd Influenza virus Viral 1 0 8.1 ± 4.0 71 ± 5 -6.8
3.1.11.01. Neuropeptide Y 1ron Homo sapiens Secreted 1 0 7.9 ± 1.6 74 ± 10 -8.6
2.1.10.01. Ceramide-1-phosphate transfer protein 4k8n Homo sapiens Eukaryo. plasma 1 0 7.0 ± 1.0 81 ± 4 -10.6
3.2.10.01. PawS derived peptide 7 2lwu Designed proteins Undefined 1 0 2.0 ± 1.4 81 ± 10 -3.0
1.2.03.02. Hepatitis A virus cellular receptor 2 homolog 3kaa Mus musculus Eukaryo. plasma 1 0 2.8 ± 2.0 55 ± 16 -5.5
2.3.06.01. Bile-salt activated lipase, conformation 1 1aql Bos taurus Secreted 1 0 5.7 ± 1.1 78 ± 7 -9.6
2.3.06.18. Tle1 effector of type VI lipase 4o5p Pseudomonas aeruginosa Secreted 1 0 3.1 ± 2.5 85 ± 8 -5.8
1.1.63.01. Type 1 signal peptidase, complex with inhibitor 1b12 Escherichia coli Bact. Gram-neg inner 1 0 5.4 ± 1.8 88 ± 7 -5.1
2.2.20.01. PH domain of GPCR kinase 2 2bcj Bos taurus Eukaryo. plasma 3 0 5.7 ± 1.5 85 ± 5 -10.4
3.3.02.01. Collagen 2wuh Homo sapiens Secreted 4 0 3.6 ± 1.6 51 ± 9 -9.5
2.2.11.01. Extended synaptotagmin-2, SMP-C2A-C2B domains 4p42 Homo sapiens Eukaryo. plasma 1 0 5.5 ± 2.8 67 ± 6 -3.3
3.1.28.03. Bombinin-H5 2ap8 Bombina variegata (Yellow-bellied toad) Secreted 1 0 8.6 ± 4.2 77 ± 3 -10.6
2.2.41.01. Chimeric beta-defensin 2/3 2lxo Designed proteins Undefined 1 0 3.6 ± 0.8 56 ± 14 -5.6
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase SMURF1 3pyc Homo sapiens Eukaryo. plasma 1 0 4.5 ± 2.1 23 ± 17 -5.7
3.1.14.01. Eledoisin 1mxq Eledone cirrhosa (Curled octopus) Secreted 1 0 2.9 ± 1.7 59 ± 19 -5.0
2.3.08.01. Patatin-like protein, PlpD 5fqu Pseudomonas aeruginosa Secreted 2 0 2.4 ± 0.6 90 ± 3 -5.6
2.4.06.01. Cholesterol-regulated Start protein 4 (StarD4) 5brl Mus musculus Eukaryo. plasma 1 0 3.7 ± 1.1 67 ± 13 -3.7
1.2.45.02. Small hydrophobic protein, peptide 39-49 2nb8 Human respiratory syncytial virus Viral 1 0 8.5 ± 1.2 57 ± 13 -5.9
2.2.51.01. 25 kDa protein elicitor 3gnz Pythium aphanidermatum Secreted 1 0 5.7 ± 2.5 77 ± 13 -5.1
2.3.16.06. ADP-ribosylation factor-like protein 1 1moz Saccharomyces cerevisiae Golgi 2 0 0.7 ± 1.1 90 ± 6 -4.3
2.2.41.01. Oral alpha defensin 1 2k1i Macaca mulatta Secreted 1 0 0.9 ± 3.2 70 ± 15 -2.2
2.3.04.01. Pteridine reductase 1 1p33 Leishmania tarentolae (Sauroleishmania tarentolae) Eukaryo. plasma 4 0 3.4 ± 1.0 73 ± 13 -7.7
3.4.02.01. Actagardine, structure in acetonitrile solution 1aj1 Actinoplanes liguriae Secreted 1 0 3.0 ± 1.1 90 ± 11 -5.7
1.2.39.02. Matrilysin, structure 1 2mze Homo sapiens Secreted 1 0 3.3 ± 0.9 68 ± 2 -8.0
2.1.15.03. Clathrin assembly lymphoid myeloid leukemia (CALM) protein 1hfa Rattus norvegicus Eukaryo. plasma 1 0 14.2 ± 2.0 44 ± 14 -17.9
2.3.18.01. Carnitine O-acetyltransferase 1ndb Mus musculus Mitochon. inner 1 0 3.0 ± 0.9 85 ± 6 -7.6
1.2.40.01. Mitochondria fission 1 protein 1y8m Saccharomyces cerevisiae Mitochon. outer 1 0 5.2 ± 0.6 88 ± 1 -5.2
2.3.06.07. Lipase 46 kDa form 2hih Staphylococcus hyicus Secreted 1 0 4.6 ± 0.3 83 ± 1 -16.0
2.1.53.01. Peroxisomal biogenesis factor 19 2wl8 Homo sapiens Peroxisome 1 0 8.3 ± 0.8 79 ± 14 -9.9
2.1.01.03. Phospholipase A2 group XIII 4aup Tuber borchii Secreted 1 0 3.7 ± 0.7 63 ± 6 -7.7
1.3.24.01. Cation efflux system protein CusC, monomer 4k7k Escherichia coli Bact. Gram-neg outer 1 0 3.2 ± 0.9 85 ± 1 -7.2
2.2.26.01. Early endosome antigen 1 (EEA1), model of dimer with lipids 1joc Homo sapiens Endosome 2 0 15.0 ± 0.4 2 ± 11 -34.0
3.2.01.05. Tachyplesin-1 2rtv Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 4.2 ± 0.4 88 ± 3 -6.8
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 1 2w61 Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.4 ± 2.3 60 ± 7 -5.4
2.2.41.01. Alpha-defensin 6 1zmq Homo sapiens Secreted 1 0 3.7 ± 1.6 76 ± 18 -3.6
3.1.28.07. Hylin-A1 analogs 5j6v Hypsiboas albopunctatus Secreted 1 0 21.2 ± 2.2 33 ± 16 -10.4
2.1.03.01. Alpha-toxin (PHLC1_CLOPE), open state 1ca1 Clostridium perfringens Secreted 1 0 2.9 ± 1.0 89 ± 4 -9.3
2.4.51.01. Heme acquisition protein HasA 4jet Yersinia pestis Secreted 1 0 4.8 ± 0.9 29 ± 2 -7.0
1.2.03.09. Programmed cell death protein 1 3sbw Mus musculus Eukaryo. plasma 1 0 2.7 ± 0.9 89 ± 4 -5.9
2.4.07.01. PX domain of sorting nexin-10 4on3 Homo sapiens Endosome 1 0 5.2 ± 1.6 69 ± 5 -7.7
3.4.09.01. Granin, cyclic analogue 1n2y Bos taurus Secreted 1 0 1.9 ± 2.1 71 ± 16 -3.4
2.2.41.02. Toxin APETx2 1wxn Anthopleura elegantissima (Sea anemone) Secreted 1 0 4.9 ± 1.7 33 ± 18 -5.5
2.3.12.01. Myotubularin-related protein 8, dimer 4y7i Homo sapiens Nuclear outer 2 0 4.3 ± 0.4 89 ± 5 -10.7
1.1.55.01. Bacterial polysaccharide co-polymerase FepE 3b8n Escherichia coli Bact. Gram-neg inner 9 0 1.6 ± 0.1 1 ± 0 -20.3
1.2.32.01. Cytochrome P450 2B4, open state 2 1po5 Oryctolagus cuniculus Endoplasm. reticulum 1 0 3.5 ± 1.4 79 ± 9 -7.2
3.4.12.01. Actinomycin D 1a7y Streptomyces antibioticus Secreted 1 0 11.5 ± 0.9 89 ± 11 -12.2
2.1.33.01. DrrA protein, PtdIns(4) binding domain, complex with PtdIns(4) 4mxp Legionella pneumophila Vacuole 1 0 2.8 ± 2.6 59 ± 12 -4.5
2.1.29.01. Apolipoprotein E 2l7b Homo sapiens Secreted 1 0 2.5 ± 1.0 73 ± 8 -4.9
2.3.06.09. Lysin B from mycobacteriophage 3hc7 Mycobacterium phage D29 Bact. Gram-pos plas. 1 0 6.6 ± 2.0 50 ± 12 -7.0
2.1.01.01. Snake phospholipase A2 homolog 2, group II 2q2j Bothrops pirajai Secreted 1 0 1.9 ± 1.2 89 ± 9 -5.6
2.1.48.01. Glycerol dehydrogenase 1kq3 Thermotoga maritima Undefined 1 0 2.5 ± 1.8 80 ± 5 -4.3
2.2.34.01. Delta conotoxin TxVIA 1fu3 Conus textile Secreted 1 0 6.5 ± 1.8 25 ± 18 -8.3
3.2.06.01. Growth-blocking peptide 2dj9 Mamestra brassicae Secreted 1 0 2.2 ± 0.7 31 ± 4 -6.2
2.1.21.01. Influenza virus matrix protein M1, structure 1 1aa7 Influenza virus Viral 2 0 2.6 ± 0.8 89 ± 4 -5.6
2.2.34.02. Toxin GsMTx2 1lup Grammostola rosea (Chilean rose tarantula) Secreted 1 0 3.8 ± 1.1 90 ± 8 -4.8
3.1.01.01. Kalata-B3/B6 propeptide 1wn8 Oldenlandia affinis Secreted 1 0 3.6 ± 1.2 81 ± 22 -8.4
2.3.27.01. Dihydrofolate reductase 3nzb Pneumocystis carinii Undefined 1 0 3.9 ± 1.9 72 ± 10 -5.9
1.2.33.02. Protoporphyrinogen oxidase 2ivd Myxococcus xanthus Bact. Gram-neg inner 1 0 3.7 ± 0.2 29 ± 2 -8.0
2.3.05.05. Secretory pathway GDP dissociation inhibitor 2bcg Saccharomyces cerevisiae Endoplasm. reticulum 2 0 3.5 ± 1.0 70 ± 6 -8.5
2.2.39.01. Cardiotoxin VI 1ug4 Naja atra Secreted 1 0 6.4 ± 0.9 62 ± 4 -12.2
2.2.35.01. Suilysin 3hvn Streptococcus suis Secreted 1 0 5.6 ± 1.1 5 ± 4 -6.4
2.2.05.01. Amicyanin 1sfd Paracoccus denitrificans Bact. Gram-neg inner 1 0 3.5 ± 0.8 49 ± 10 -4.0
2.2.14.01. C2 domain of coagulation factor VIII 1d7p Homo sapiens Eukaryo. plasma 1 0 4.8 ± 2.0 28 ± 10 -8.8
3.4.13.01. T-cell-specific surface glycoprotein CD28, intracellular loop 2nae Mus musculus Eukaryo. plasma 1 0 0.9 ± 10.0 81 ± 3 -6.4
2.1.21.04. Matrix protein p19 1a6s Rous sarcoma virus Viral 1 0 3.1 ± 2.7 89 ± 14 -3.6
3.2.06.01. Paralytic peptide 1 1hrl Manduca sexta Secreted 1 0 6.5 ± 0.6 51 ± 6 -6.2
2.2.20.01. PH domain of GPCR kinase 1 1bak Homo sapiens Eukaryo. plasma 1 0 3.6 ± 0.9 88 ± 2 -6.0
2.2.12.01. Mite group 2 allergen Der p 2 1ktj Dermatophagoides pteronyssinussearch Secreted 1 0 1.4 ± 1.3 65 ± 9 -3.2
3.1.05.13. Cullin3-derived peptides 2myl Designed proteins Undefined 1 0 3.4 ± 1.2 82 ± 21 -4.4
1.2.57.01. Reticulon-4 2ko2 Mus musculus Endoplasm. reticulum 1 0 2.5 ± 0.3 83 ± 1 -6.2
2.3.06.06. Lipase 2 1gz7 Candida rugosa Secreted 1 0 4.8 ± 1.3 87 ± 10 -8.5
3.1.35.01. Cn-AMP1 peptide 2n0v Cocos nucifera Secreted 1 0 2.9 ± 1.3 73 ± 18 -2.3
2.4.05.01. Sterol carrier protein 2 2cx7 Thermus thermophilus Bact. Gram-neg inner 1 0 4.7 ± 1.3 73 ± 13 -6.9
2.2.06.02. Cellular retinoic acid-binding protein 1 1cbr Bos taurus Eukaryo. plasma 1 0 6.5 ± 1.1 45 ± 11 -5.4
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 2 3c6e Dengue virus Viral 1 0 2.9 ± 2.7 42 ± 5 -3.6
2.2.21.03. Interleukin-36 receptor antagonist protein 1md6 Mus musculus Secreted 1 0 3.8 ± 0.4 40 ± 3 -6.5
1.3.17.02. BamCD lipoprotein complex 3tgo Escherichia coli Bact. Gram-neg outer 2 0 3.7 ± 2.1 81 ± 20 -3.3
2.4.16.01. Beta-toxin Cn5 2kja Centruroides noxius (Mexican scorpion) Secreted 1 0 4.1 ± 1.1 73 ± 6 -7.0
2.4.15.01. Protein Nef, complex with tyrosine-protein kinase SH3 domain (HIV HV1A2) 3rbb Human immunodeficiency virus type 1 Eukaryo. plasma 2 0 2.4 ± 1.1 84 ± 6 -4.2
3.1.19.01. Zervamicin IIb 1ih9 Emericellopsis salmosynnemata Secreted 1 0 11.5 ± 2.0 74 ± 10 -12.3
2.2.34.06. Peptide jS1 2n5q Jasminum sambac Secreted 1 0 3.8 ± 1.2 71 ± 15 -6.1
2.3.05.02. Sulfide-quinone reductase 3h28 Aquifex aeolicus Bact. Gram-neg inner 3 0 2.4 ± 0.1 90 ± 0 -19.4
2.2.12.02. Rho GDP-dissociation inhibitor 1 1qvy Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.7 53 ± 19 -5.1
2.1.01.01. Ammodytin L1 isoform 3ux7 Vipera ammodytes meridionalis Secreted 1 0 2.7 ± 0.3 82 ± 1 -13.2
2.2.20.01. Collagen type IV alpha-3-binding protein 2rsg Homo sapiens Golgi 1 0 4.7 ± 0.9 60 ± 8 -7.0
2.4.16.04. Defensin 2 (PDF1) 2gl1 Vigna radiata (Mung bean) Secreted 1 0 2.8 ± 0.6 6 ± 4 -5.7
2.4.33.01. 72 kDa type IV collagenase, complex with inhibitor-2 1gxd Homo sapiens Eukaryo. plasma 2 0 2.5 ± 1.1 77 ± 4 -5.4
2.3.06.01. Bile-salt activated lipase, conformation 3 2bce Bos taurus Secreted 1 0 5.3 ± 0.8 74 ± 6 -7.0
2.2.39.02. Mambalgin-2 2mfa Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 2.7 ± 2.5 76 ± 5 -6.4
2.2.20.01. Son of sevenless homolog 1 (SOS-1) 1xd4 Homo sapiens Eukaryo. plasma 1 0 1.9 ± 3.0 79 ± 2 -4.5
2.3.17.02. Folic acid synthesis protein FOL1 2bmb Saccharomyces cerevisiae Mitochon. inner 1 0 2.0 ± 0.6 31 ± 2 -5.8
2.3.18.02. Phthiocerol/phthiodiolone dimycocerosyl transferase 1q9j Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 6.7 ± 2.2 25 ± 6 -5.2
2.3.06.08. Pancreatic lipase, complex with colipase from Pig 1lpa Homo sapiens Secreted 2 0 11.3 ± 0.1 82 ± 1 -24.5
2.1.42.01. Lactococcin-A immunity protein 5lfi Lactococcus lactis Secreted 1 0 2.7 ± 1.4 40 ± 9 -4.8
2.2.27.01. C1 domain of unc-13 homolog A 1y8f Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 1.9 16 ± 17 -2.9
1.2.32.01. Cytochrome P450 11B2, mitochondrial 4dvq Homo sapiens Mitochon. inner 1 0 4.8 ± 0.6 48 ± 4 -9.1
2.2.41.03. Big defensin 2rng Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 6.5 ± 2.3 21 ± 4 -7.5
2.2.39.01. Muscarinic m1-toxin1, chimeric sequence 3fev Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 5.5 ± 1.5 76 ± 8 -6.3
2.2.20.01. Myosin X 3tfm Rattus norvegicus Endosome 1 0 1.5 ± 2.6 81 ± 5 -3.0
2.4.16.02. Nasonin 2koz Nasonia vitripennis (Parasitic wasp) Secreted 1 0 2.9 ± 0.9 68 ± 7 -4.6
2.1.01.01. Snake phospholipase A2, group II (ecarpholin S) 2qhd Echis carinatus Secreted 1 0 8.1 ± 0.6 79 ± 5 -12.5
2.3.06.04. Palmitoyl protein thioesterase 1 1eh5 Bos taurus Lysosome 1 0 5.3 ± 0.9 59 ± 6 -8.1
2.1.04.01. Prostaglandin H2 synthase-2 (cyclooxygenase) 1cx2 Mus musculus Endoplasm. reticulum 2 0 9.7 ± 0.4 89 ± 3 -37.4
2.1.01.01. Snake phospholipase A2, group II 1jlt Vipera ammodytes meridionalis Secreted 1 0 2.8 ± 1.0 89 ± 7 -8.7
3.1.20.01. Conotoxin pc16a 2ler Conus pictus Secreted 1 0 4.0 ± 1.0 64 ± 7 -4.1
1.1.59.01. Membrane protease specific for a stomatin homolog, dimer 3viv Pyrococcus horikoshii Archaebac. 2 0 4.5 ± 0.4 88 ± 9 -9.5
2.4.16.04. Defensin-like protein 1brz Pentadiplandra brazzeana Secreted 1 0 1.2 ± 1.2 83 ± 10 -3.6
2.2.16.01. Lipoprotein lppX 2byo Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 1.9 ± 1.7 80 ± 13 -4.8
1.2.38.02. Lysozyme 3hde Enterobacteria phage p21 Secreted 1 0 1.8 ± 1.4 55 ± 10 -4.7
3.4.07.01. Antimicrobial cationic cyclic hexapeptide 1qvl Designed proteins Undefined 1 0 4.2 ± 1.6 84 ± 15 -6.8
2.1.02.01. Seed lipoxygenase-3 1rrh Glycine max Eukaryo. plasma 1 0 3.8 ± 1.3 84 ± 7 -5.6
1.2.32.01. Cytochrome P450 2C5, different conformation 1dt6 Oryctolagus cuniculus Endoplasm. reticulum 1 0 7.3 ± 1.0 13 ± 7 -8.8
2.2.02.01. Exfoliative toxin B 1qtf Staphylococcus aureus Secreted 1 0 2.8 ± 1.9 81 ± 11 -5.8
3.2.05.02. Lassomycin 2mai Lentzea kentuckyensis Secreted 1 0 3.1 ± 1.0 72 ± 9 -4.7
2.2.18.01. Subunit mu of AP-2 clatrin adaptor complex, open conformation 2xa7 Rattus norvegicus Vesicle 4 0 3.1 ± 2.2 84 ± 14 -5.9
2.2.34.01. Conotoxin mr3e 2efz Conus marmoreus Secreted 1 0 1.0 ± 1.3 83 ± 25 -3.2
2.1.30.01. Membrane-integrating protein mistic, mstX 1ygm Bacillus subtilis Bact. Gram-pos plas. 1 0 2.6 ± 1.8 31 ± 6 -5.2
2.1.01.01. Snake phospholipase A2, acidic, group I 2wq5 Naja naja Secreted 1 0 3.4 ± 0.3 89 ± 6 -6.2
2.3.22.01. Uncharacterized protein 1rtt Pseudomonas aeruginosa Undefined 1 0 3.1 ± 2.5 70 ± 22 -4.1
2.3.18.01. Choline O-acetyltransferase 1q6x Rattus norvegicus Eukaryo. plasma 1 0 3.6 ± 0.6 75 ± 6 -8.5
1.2.32.01. Cytochrome P450 1B1 3pm0 Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 0.7 79 ± 1 -7.0
2.2.34.04. Leginsulin 1ju8 Glycine max Secreted 1 0 11.3 ± 1.6 21 ± 17 -8.6
2.2.35.01. Intermedilysin - CD59 receptor complex, disulfide-locked mutant 4bik Streptococcus intermedius Secreted 1 0 5.9 ± 3.1 28 ± 43 -6.4
2.1.18.01. Annexin VIII 1w3w Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.0 79 ± 9 -6.2
3.1.20.01. Alpha-conotoxin Vc1A 2h8s Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.8 59 ± 6 -2.5
2.1.02.01. Arachidonate 15-lipoxygenase 4nre Homo sapiens Eukaryo. plasma 1 0 4.5 ± 1.5 83 ± 2 -10.6
3.1.29.03. Prophenin-1 analogues 2i1e Sus scrofa Secreted 1 0 5.2 ± 1.0 53 ± 7 -7.5
3.1.05.03. LAK160-P10 2l99 Designed proteins Undefined 1 0 3.9 ± 2.6 84 ± 0 -5.0
2.2.20.01. Pleckstrin homology domain-containing family A member 6 (PLEKHA6) 2d9y Homo sapiens Eukaryo. plasma 1 0 1.0 ± 0.3 67 ± 1 -6.2
2.1.04.01. Alpha-dioxygenase 1 4hhr Arabidopsis thaliana Endoplasm. reticulum 1 0 10.8 ± 0.1 68 ± 2 -31.4
2.2.41.01. Alpha-defensin corticostatin-related peptide RK-1 1ews Oryctolagus cuniculus Secreted 1 0 4.7 ± 1.1 18 ± 17 -4.4
2.2.35.01. Pneumolysin, structure 1 4qqq Streptococcus pneumoniae Secreted 1 0 4.6 ± 3.7 27 ± 7 -6.8
2.2.20.01. Dynamin-1 1dyn Homo sapiens Eukaryo. plasma 2 0 4.1 ± 1.2 88 ± 15 -9.7
2.2.60.01. Matrix protein VP40 1es6 Zaire ebolavirus Viral 1 0 2.1 ± 0.5 80 ± 3 -6.7
2.2.39.01. Muscarinic m1-toxin1, sequence version 3neq Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 4.0 ± 0.8 65 ± 5 -7.0
2.3.02.04. Phosphatidylinositol-specific phospholipase C1 3h4x Streptomyces antibioticus Bact. Gram-pos plas. 1 0 3.7 ± 0.4 63 ± 2 -7.3
1.3.25.01. Gamma-hemolysin, component B 3lkf Staphylococcus aureus Secreted 1 0 1.7 ± 2.5 51 ± 11 -4.5
3.2.01.09. Transthyretin-derived peptide 5hpp Designed proteins Undefined 1 0 2.7 ± 1.6 83 ± 6 -5.2
3.1.04.03. Viral protein R, peptide 13-33, different strain 1fi0 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 2.7 ± 1.2 88 ± 8 -8.6
2.3.06.09. Cutinase 1 1oxm Fusarium solani Secreted 1 0 6.8 ± 1.1 36 ± 15 -9.1
3.1.28.04. Esculentin-1A 2n6m Pelophylax esculentus Secreted 1 0 7.9 ± 0.4 67 ± 5 -7.9
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 405-424 1btq Homo sapiens Eukaryo. plasma 1 0 13.6 ± 2.1 67 ± 11 -22.5
2.4.44.01. Membrane-associated protein VP24, with karyopherin 4u2x Zaire ebolavirus Viral 2 0 4.5 ± 2.1 33 ± 15 -4.3
2.2.34.02. Neurotoxin Hm-3 2mqu Heriaeus melloteei Secreted 1 0 2.4 ± 0.6 75 ± 11 -7.4
2.3.13.01. Microsomal prostaglandin E synthase 2 1z9h Macaca fascicularis Golgi 2 0 4.8 ± 0.5 90 ± 4 -15.7
2.1.42.01. Immunity protein for enterocin A (Entl) 2bl7 Enterococcus faecium Secreted 1 0 3.3 ± 1.0 89 ± 3 -4.5
3.1.04.03. Viral protein R, peptide 34-51 1kzt Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.4 ± 0.6 77 ± 7 -10.3
3.2.01.08. Lactoferricin B, peptide 36-60 1lfc Bos taurus Secreted 1 0 4.6 ± 0.5 90 ± 6 -5.3
2.2.41.01. Gallinacin-7 5lcs Gallus gallus Secreted 1 0 2.5 ± 1.4 85 ± 5 -5.6
2.3.20.01. Hydrophilic domain of respiratory complex I 3i9v Thermus thermophilus Bact. Gram-neg inner 8 0 5.1 ± 1.4 34 ± 10 -11.6
2.2.20.01. PH domain of TAPP2 1v5p Mus musculus Eukaryo. plasma 1 0 1.4 ± 1.3 61 ± 5 -3.7
2.3.18.01. Carnitine O-palmitoyltransferase 1, liver isoform, N-terminal domain 2le3 Homo sapiens Mitochon. outer 1 0 3.9 ± 3.7 80 ± 3 -9.3
2.1.60.01. Potassium channel toxin ShK 1roo Stoichactis helianthus Secreted 1 0 1.2 ± 1.2 46 ± 8 -3.7
3.1.04.10. TAR DNA-binding protein 43, peptide 307-349 2n2c Homo sapiens Nuclear inner 1 0 7.7 ± 0.7 89 ± 6 -13.4
2.4.12.01. Liver-expressed antimicrobial peptide 2 2l1q Homo sapiens Secreted 1 0 5.3 ± 1.4 56 ± 11 -2.7
1.1.26.07. STAS domain of anion permease 3oiz Rhodobacter sphaeroides Bact. Gram-neg inner 1 0 3.9 ± 0.4 18 ± 5 -5.4
1.2.03.02. SLAM family member 6 2if7 Homo sapiens Eukaryo. plasma 3 0 2.0 ± 3.3 88 ± 11 -7.1
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), structure 1 5tz1 Candida albicans Endoplasm. reticulum 1 0 8.7 ± 0.9 67 ± 4 -16.2
2.2.34.06. Antimicrobial peptide 1 1dkc Phytolacca americana (American pokeweed) Secreted 1 0 3.5 ± 1.2 84 ± 10 -4.1
2.1.02.01. 9R-lipoxygenase 5ek8 Synechococcus sp. Bact. Gram-neg inner 1 0 4.0 ± 0.7 78 ± 6 -12.2
1.2.36.01. Hemagglutinin-neuraminidase glycoprotein 1v3e Human parainfluenza virus 3 Eukaryo. plasma 2 0 1.9 ± 0.4 81 ± 34 -6.5
2.1.08.01. Cytochrome c6 1c6s Thermosynechococcus elongatus Thylakoid 1 0 0.4 ± 1.7 89 ± 16 -1.3
2.4.11.01. Alpha-1-purothionin 2plh Triticum aestivum Secreted 1 0 2.4 ± 2.0 53 ± 17 -4.6
3.1.20.01. O2-contryphan-Vc2 5l34 Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.4 85 ± 8 -4.2
2.2.20.01. Cytohesin-3 (Grp1) 1fhx Mus musculus Eukaryo. plasma 1 0 15.0 ± 1.2 18 ± 15 -16.4
2.3.11.01. Ferrochelatase, conformation 2 (with porphyrin bound) 4klr Homo sapiens Mitochon. inner 2 0 1.3 ± 0.0 90 ± 1 -8.4
3.1.19.01. Chrysospermin C 1ee7 Apiocrea chrysosperma Secreted 1 0 9.8 ± 2.3 82 ± 12 -12.2
2.3.34.01. N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D 4qn9 Homo sapiens Eukaryo. plasma 2 0 6.0 ± 1.6 87 ± 11 -11.3
3.1.07.02. Peptide of envelope glycoprotein H (625-644) 2lqy Human herpesvirus Endosome 1 0 3.2 ± 0.8 88 ± 5 -10.2
2.1.44.01. Bacteriocin glycocin F 2kuy Lactobacillus plantarum Secreted 1 0 5.4 ± 1.2 65 ± 6 -6.2
1.1.56.01. Inner membrane protein YejM, strain LT2 5i5f Salmonella typhimurium Bact. Gram-neg inner 1 0 3.7 ± 2.4 62 ± 11 -4.9
2.1.24.01. Saposin A (peptide 60-140), conformation in disc 4ddj Homo sapiens Lysosome 1 0 6.4 ± 0.9 89 ± 3 -8.5
2.3.16.09. GTP-binding protein YjiA 1nij Escherichia coli Bact. Gram-neg inner 1 0 3.4 ± 0.1 41 ± 1 -6.7
1.2.32.01. Cytochrome P450 2A6 1z10 Homo sapiens Endoplasm. reticulum 1 0 5.0 ± 1.7 44 ± 18 -9.5
2.1.01.01. Snake phospholipase A2, group II, VRV-PL-VIIIa 1zwp Daboia russelli pulchella Secreted 1 0 4.9 ± 1.0 76 ± 7 -12.5
3.2.04.03. Peptide leucine arginine 2m3n Lithobates pipiens Secreted 1 0 4.7 ± 0.6 83 ± 5 -5.7
1.2.03.02. Hepatitis A virus cellular receptor 1 5f70 Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.4 61 ± 13 -4.4
2.1.33.01. DrrA protein, PtdIns(4) binding domain 3n6o Legionella pneumophila Vacuole 1 0 5.1 ± 1.4 56 ± 10 -4.9
3.1.15.03. Bacteriocin peptide plantaricin F (PlnF) 2rlw Lactobacillus plantarum Secreted 1 0 8.7 ± 4.4 79 ± 5 -11.7
2.1.34.01. Septium site-determining protein DivIVA 2wuj Bacillus subtilis Bact. Gram-pos plas. 2 0 4.0 ± 1.8 2 ± 18 -5.4
3.1.07.03. Antimicrobial peptide derived from hemagglutinin 2l24 Influenza virus Undefined 1 0 8.7 ± 1.3 75 ± 10 -12.6
2.2.11.01. Multiple C2 and transmembrane domain-containing protein 2 (MCTP2) 2ep6 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.5 7 ± 15 -3.0
1.2.32.01. Cytochrome P450 2E1 3e6i Homo sapiens Endoplasm. reticulum 1 0 8.3 ± 2.0 49 ± 8 -14.2
2.2.34.11. Kalata B2, segment 71-98 (repeat 1) 1pt4 Oldenlandia affinis Secreted 1 0 4.6 ± 1.2 83 ± 14 -9.2
2.1.60.03. Pseudecin, conformation 1 2ddb Pseudechis porphyriacus Secreted 1 0 4.8 ± 0.7 90 ± 3 -5.4
2.2.11.01. Cytosolic phospholipase A2, group IVA 1rlw Homo sapiens Eukaryo. plasma 1 0 6.4 ± 1.9 57 ± 17 -7.8
2.2.11.01. Synaptotagmin-7 3n5a Mus musculus Vesicle 1 0 2.2 ± 2.3 30 ± 12 -4.1
2.2.34.02. Delta-amaurobitoxin-Pl1a 1v90 Pireneitega luctuosa (Tangled nest spider) Secreted 1 0 2.9 ± 0.7 26 ± 14 -4.0
2.3.26.01. Phosphate acyltransferase 1u7n Enterococcus faecalis Bact. Gram-pos plas. 2 0 6.1 ± 1.5 78 ± 13 -6.1
2.3.06.09. Cutinase 1 3gbs Aspergillus oryzae Secreted 1 0 11.2 ± 0.5 55 ± 5 -12.6
2.3.13.04. Glutathione peroxidase-like protein 2vup Trypanosoma brucei Undefined 1 0 3.0 ± 1.7 84 ± 7 -4.1
2.3.06.05. Acyl-protein thioesterase 1 1fj2 Homo sapiens Eukaryo. plasma 1 0 9.6 ± 2.0 64 ± 14 -4.7
1.2.32.01. Steroid 17-alpha-hydroxylase/17,20 lyase (P450 17A1) 3swz Homo sapiens Endoplasm. reticulum 1 0 4.2 ± 1.6 56 ± 3 -8.4
2.4.16.02. Defensin ARD1 1ozz Archaeoprepona demophon Secreted 1 0 4.9 ± 1.7 31 ± 17 -7.1
2.1.20.01. Coagulation factor IX 1pfx Sus scrofa Eukaryo. plasma 2 0 1.9 ± 6.0 84 ± 10 -3.9
1.2.43.01. Envelope glycoprotein, Dengue virus type 1 3g7t Dengue virus Viral 3 0 5.9 ± 0.9 1 ± 3 -12.2
3.1.11.01. Peptide YY 2dez Homo sapiens Secreted 1 0 4.0 ± 0.2 84 ± 2 -5.9
2.1.10.01. Ceramide-1-phosphate transfer protein 4kbr Mus musculus Eukaryo. plasma 1 0 3.5 ± 1.5 77 ± 10 -6.9
2.1.01.01. Phospholipase A2 2not Notechis scutatus scutatus (Mainland tiger snake) Secreted 1 0 2.6 ± 1.5 73 ± 8 -3.9
3.1.05.03. LAK160-P7 2l96 Designed proteins Undefined 1 0 1.4 ± 0.9 88 ± 5 -2.7
1.2.03.02. T-cell immunoglobulin and mucin domain-containing protein 2 2or7 Mus musculus Eukaryo. plasma 1 0 0.9 ± 0.7 54 ± 6 -3.3
2.3.06.01. Bile-salt activated lipase, structure 1 1f6w Homo sapiens Secreted 1 0 1.8 ± 0.5 81 ± 10 -5.1
2.3.06.01. Carboxylic ester hydrolase, open state 4be9 Ophiostoma piceae Secreted 1 0 8.7 ± 0.4 88 ± 2 -30.9
1.1.63.01. Type 1 signal peptidase, apo-enzyme 1kn9 Escherichia coli Bact. Gram-neg inner 1 0 3.4 ± 1.4 80 ± 6 -7.8
2.2.06.02. Muscle fatty acid binding protein 1hmt Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.6 49 ± 12 -5.0
2.1.21.02. Matrix protein p10, myristoylated, structure 2 2mxi Mason-Pfizer monkey virus Viral 1 0 3.8 ± 0.7 58 ± 3 -6.3
3.2.08.01. Peptide 30-35 2y3j Homo sapiens Secreted 4 0 4.0 ± 1.4 86 ± 6 -6.2
2.1.24.01. Saposin D (peptide 405-486) 2rb3 Homo sapiens Secreted 1 0 2.2 ± 1.7 88 ± 10 -3.4
3.2.11.01. Peptide NC_cEE_D1 5kx2 Designed proteins Undefined 1 0 4.9 ± 1.9 70 ± 14 -4.6
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4, complex with GRB10 3m7f Mus musculus Eukaryo. plasma 2 0 2.2 ± 2.0 76 ± 13 -2.7
3.1.14.01. Neurokinin A 1n6t Gallus gallus Secreted 1 0 6.8 ± 1.2 60 ± 17 -4.9
3.1.11.02. Exendin-4-conotoxin chimera 2naw Designed proteins Secreted 1 0 4.3 ± 1.4 69 ± 8 -2.7
2.4.06.01. Phosphatidylcholine transfer protein 1ln1 Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 53 ± 16 -4.8
2.4.09.01. T4 capsid assembly protease, gp21 5jbl Enterobacteria phage T4 Viral 5 0 3.6 ± 0.2 89 ± 0 -12.0
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 1 3mok Pseudomonas aeruginosa Secreted 1 0 4.5 ± 0.7 37 ± 7 -6.7
2.3.16.06. ADP-ribosylation factor-like protein 3 1fzq Mus musculus Golgi 1 0 3.3 ± 1.1 73 ± 9 -5.8
2.2.41.01. Neutrophil defensin 1, dimer 3gny Homo sapiens Secreted 2 0 3.5 ± 0.5 84 ± 6 -5.0
1.2.01.01. Insulin-like growth factor 1 receptor 1p4o Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.0 37 ± 11 -5.1
3.4.02.02. Mersacidin, crystal structure 1qow Bacillus sp. Secreted 3 0 3.2 ± 2.7 72 ± 31 -5.5
1.2.39.02. Matrilysin, structure 2 2mzi Homo sapiens Secreted 1 0 3.5 ± 0.5 71 ± 4 -7.7
2.2.20.01. PH domain of tyrosine-protein kinase BTK 1bwn Homo sapiens Eukaryo. plasma 2 0 15.3 ± 0.5 90 ± 10 -33.3
2.3.18.01. Carnitine O-octanoyltransferase 1nm8 Homo sapiens Mitochon. inner 1 0 1.7 ± 3.0 67 ± 15 -5.3
1.2.40.01. Mitochondria fission 1 protein, NMR 1pc2 Homo sapiens Mitochon. outer 1 0 8.5 ± 2.5 48 ± 23 -8.0
2.2.34.11. Kalata-B8 2b38 Oldenlandia affinis Secreted 1 0 5.5 ± 1.0 88 ± 12 -5.6
2.2.11.01. C2 domain of abscisic acid-related protein CAR1 5a50 Arabidopsis thaliana Eukaryo. plasma 1 0 3.4 ± 1.2 79 ± 4 -6.3
2.2.09.05. Peroxisomal targeting signal 2 receptor, comnplex with Pex21p and thiolase 3w15 Saccharomyces cerevisiae Peroxisome 3 0 5.2 ± 1.6 84 ± 7 -5.8
2.3.06.02. Antigen 85c, conformation 2 4qdu Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 5.3 ± 2.4 87 ± 16 -5.2
3.1.28.03. Maximin-4 2mhw Bombina maxima Secreted 1 0 4.4 ± 1.0 75 ± 3 -6.3
2.2.23.01. Lipoprotein BamB, conformation 3 3q7o Escherichia coli Bact. Gram-neg outer 1 0 4.9 ± 1.5 69 ± 3 -6.9
2.4.07.01. PX domain of serine/threonine-protein kinase Sgk3 1xte Homo sapiens Endosome 1 0 1.2 ± 1.4 77 ± 11 -2.9
3.1.28.04. Phylloseptin-3 2jq1 Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 6.4 ± 0.8 74 ± 9 -9.5
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 2 2w62 Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.7 ± 0.5 90 ± 1 -6.1
2.2.08.01. Osmotin-like protein 1aun Nicotiana tabacum Secreted 1 0 5.8 ± 1.0 85 ± 11 -6.7
3.1.28.09. Pseudin-2 2ncy Pseudis paradoxa Secreted 1 0 4.9 ± 3.0 77 ± 5 -5.8
2.1.01.01. Snake phospholipase A2, group I 1poa Naja atra Secreted 1 0 4.8 ± 1.0 89 ± 7 -10.7
2.4.51.01. Heme acquisition protein HasA, apoprotein 4jes Yersinia pestis Secreted 1 0 5.2 ± 0.3 40 ± 2 -9.6
2.2.11.01. C2 domain of GTPase activating protein 1 4rj9 Oryza sativa (Rice) Eukaryo. plasma 1 0 3.7 ± 1.4 16 ± 6 -5.6
3.1.07.02. Juxtamembrane peptide (659-685) of protein gp160 2fx7 Human immunodeficiency virus type 1 Endosome 1 0 6.2 ± 1.0 73 ± 7 -8.0
3.4.09.01. Granin 1lv4 Homo sapiens Secreted 1 0 1.8 ± 0.4 81 ± 3 -6.8
2.4.20.04. Group XVI phospholipase A1/A2 2kyt Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.5 62 ± 18 -4.9
2.2.34.02. Huwentoxin-4 1mb6 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 4.4 ± 0.8 70 ± 12 -5.8
2.3.13.06. Chloride intracellular channel protein 1 1rk4 Homo sapiens Nuclear outer 1 0 3.0 ± 1.0 40 ± 5 -5.5
1.1.62.01. Diguanylate cyclase/phosphodiesterase 3pjv Pseudomonas fluorescens Bact. Gram-neg inner 5 0 4.6 ± 1.5 79 ± 4 -6.6
2.3.04.01. Corticosteroid 11-beta-dehydrogenase, isozyme 1 1y5m Mus musculus Endoplasm. reticulum 2 0 4.6 ± 0.4 89 ± 2 -19.3
2.1.28.01. Heat-stable enterotoxin II 1ehs Escherichia coli Secreted 1 0 1.4 ± 1.1 64 ± 11 -6.0
3.4.12.01. Actinomycin Z3 1a7z Streptomyces antibioticus Secreted 1 0 10.0 ± 1.3 76 ± 24 -9.6
2.1.63.01. Lipid A biosynthesis lauroyl acyltransferase 5kn7 Acinetobacter baumannii Bact. Gram-neg outer 1 0 7.4 ± 1.4 66 ± 0 -7.5
1.1.71.01. Legionalla phosphoinositide phosphatase, SidP 4jza Legionella pneumophila Vacuole 1 0 2.6 ± 1.7 57 ± 7 -5.6
2.1.29.03. Apolipoprotein C-I, peptide 33-50 1ale Homo sapiens Secreted 1 0 4.9 ± 1.0 72 ± 4 -7.8
2.4.07.01. Sorting nexin-11, conformation 1 4ikb Homo sapiens Eukaryo. plasma 1 0 5.2 ± 2.7 61 ± 8 -6.1
2.1.01.01. Snake phospholipase A2, acidic 2, group I 1p7o Micropechis ikaheka Secreted 1 0 2.6 ± 0.5 90 ± 2 -9.4
2.3.24.02. Phosphoglycolate phosphatase 1l6r Thermoplasma acidophilum Undefined 1 0 3.6 ± 0.5 86 ± 3 -7.5
2.2.34.01. Mu-O conotoxin MrVIB 1rmk Conus marmoreus Secreted 1 0 10.1 ± 1.3 62 ± 19 -10.7
3.2.01.08. Lactoferricin B, peptide 10-19 1y5c Bos taurus Secreted 1 0 2.2 ± 1.2 54 ± 11 -3.4
3.1.07.02. Paramyxovirus sv5 fusion protein core 1svf Simian virus 5 Viral 6 0 8.4 ± 0.9 0 ± 11 -10.7
3.1.20.01. Alpha-conotoxin PIVA 1p1p Conus purpurascens (Purple cone) Secreted 1 0 2.4 ± 1.0 30 ± 11 -3.8
2.2.06.01. Outer membrane lipoprotein Blc 1qwd Escherichia coli Bact. Gram-neg outer 1 0 3.2 ± 2.0 80 ± 15 -4.6
3.1.01.01. Varv peptide A/Kalata-B1 propeptide 1wn4 Viola odorata Secreted 1 0 6.4 ± 1.1 81 ± 14 -7.2
2.2.09.02. Diisopropyl-fluorophosphatase 3o4p Loligo vulgaris (Common European squid) Undefined 1 0 4.6 ± 1.3 82 ± 5 -6.6
1.2.07.01. Protein spitz 3ca7 Drosophila melanogaster Endoplasm. reticulum 1 0 3.3 ± 2.8 87 ± 3 -4.3
2.2.39.01. Cardiotoxin II (cytotoxin II) 1ffj Naja naja oxiana Secreted 1 0 7.9 ± 0.8 56 ± 5 -13.7
2.4.37.01. Monalysin 4mjt Pseudomonas entomophila Secreted 9 0 1.6 ± 0.0 90 ± 0 -13.5
2.2.05.01. Amicyanin 1id2 Paracoccus versutus Bact. Gram-neg inner 1 0 4.2 ± 1.3 52 ± 8 -4.9
2.1.02.01. 8R-Lipoxygenase, central and C-terminal domains 3fg3 Plexaura homomalla Eukaryo. plasma 1 0 5.0 ± 0.6 86 ± 5 -9.3
2.1.21.02. Matrix protein p10, myristoylated, structure 1 2lpy Mason-Pfizer monkey virus Viral 1 0 3.2 ± 0.5 8 ± 6 -3.4
3.2.06.01. Paralytic peptide 2 1v28 Manduca sexta Secreted 1 0 2.9 ± 1.4 90 ± 16 -4.9
2.2.12.01. Mite group 2 allergen Der f 2 1xwv Dermatophagoides farinae (American house dust mite) Secreted 1 0 1.2 ± 1.4 64 ± 10 -3.1
3.1.04.09. Membrane-permeabilizing peptide (654-676) from hemocyanin 2n1c Litopenaeus vannamei (Whiteleg shrimp) Undefined 1 0 6.5 ± 1.3 90 ± 9 -6.3
3.1.02.07. Sodium/hydrogen exchanger 1, TM helices 2kbv Homo sapiens Eukaryo. plasma 1 0 2.7 ± 6.9 74 ± 4 -4.9
1.2.53.01. Squalene synthase, conformation 1 3v66 Homo sapiens Endoplasm. reticulum 1 0 3.1 ± 0.8 83 ± 6 -5.1
2.3.06.06. Type-B carboxylesterase/lipase 1cle Candida cylindracea Secreted 1 0 10.2 ± 0.0 83 ± 0 -24.7
3.1.15.01. Enterocin-HF 2n4k Enterococcus faecium Secreted 1 0 4.8 ± 3.5 82 ± 4 -4.8
2.2.06.02. Cellular retinol-binding protein II 1crb Rattus norvegicus Eukaryo. plasma 1 0 2.4 ± 1.7 52 ± 19 -5.3
1.2.51.01. Alkaline sphingomyelinase 5udy Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.3 84 ± 10 -4.5
1.2.43.01. Envelope glycoprotein, West Nile virus, structure 3 3i50 West Nile virus Viral 1 0 6.3 ± 2.8 27 ± 19 -4.4
2.2.07.03. Streptavidin 1mm9 Streptomyces avidinii Secreted 1 0 4.2 ± 1.6 56 ± 3 -8.4
2.4.16.01. Alpha-toxin CsE5 1nra Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.3 ± 1.2 89 ± 22 -4.3
2.3.10.07. Lipopolysaccharide biosynthesis protein RfaG 2iw1 Escherichia coli Bact. Gram-neg inner 1 0 3.7 ± 3.1 85 ± 8 -6.0
2.2.06.02. Fatty acid-binding protein 9 4a60 Homo sapiens Eukaryo. plasma 1 0 3.2 ± 1.1 38 ± 6 -4.6
3.1.19.01. Trichotoxin a50e 1m24 Trichoderma viride Secreted 1 0 10.4 ± 1.8 75 ± 32 -14.3
2.2.34.02. Beta-theraphotoxin-Tp2a 2n9t Thrixopelma pruriens Secreted 1 0 1.7 ± 0.1 60 ± 1 -7.2
1.1.49.01. ATP-dependent zinc metalloprotease FtsH 3kds Thermotoga maritima Bact. Gram-neg inner 6 0 2.2 ± 0.4 90 ± 0 -12.8
1.2.55.01. Neutral ceramidase 4wgk Homo sapiens Eukaryo. plasma 1 0 4.1 ± 0.5 80 ± 2 -10.0
2.2.41.01. Gallinacin-2 2lg5 Gallus gallus Secreted 1 0 8.0 ± 1.2 62 ± 6 -8.2
2.2.50.01. Lipoprotein TP0453, open conformation 3k8i Treponema pallidum Bact. Gram-neg outer 1 0 8.9 ± 2.4 38 ± 2 -12.0
2.1.41.01. Phosphatidylinositol 4-kinase type 2-alpha, structure 1 4hne Homo sapiens Golgi 1 0 7.2 ± 2.4 35 ± 0 -8.5
3.1.29.01. Cathelin-related peptide SC5 (SMAP-29) 1fry Ovis aries Secreted 1 0 1.1 ± 0.8 18 ± 9 -3.5
2.4.33.01. 72 kDa type IV collagenase, full-length 1ck7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 73 ± 9 -4.0
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1gym Bacillus cereus Secreted 1 0 4.9 ± 1.0 67 ± 11 -7.2
2.2.34.02. Spiderine-1a, 108-165 2n86 Oxyopes takobius (Lynx spider) Secreted 1 0 5.8 ± 3.7 57 ± 6 -5.7
2.2.20.01. PH domain containing retinal protein 1 2d9v Mus musculus Eukaryo. plasma 1 0 1.3 ± 1.3 58 ± 14 -5.1
2.3.05.04. Reticulon-4-interacting protein 1 2vn8 Homo sapiens Mitochon. inner 1 0 4.0 ± 0.0 82 ± 0 -10.2
2.2.06.01. Retinol binding protein, plasma isoform 1iiu Gallus gallus Secreted 1 0 1.9 ± 1.8 35 ± 17 -4.4
2.2.34.12. Poneritoxin, omega-PONTX-Ae1a 2nbc Anochetus emarginatus Secreted 1 0 1.7 ± 1.8 72 ± 12 -2.5
2.2.27.01. C1 domanin of SH3 and cysteine-rich domain-containing protein 3 2db6 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 0.1 75 ± 0 -4.8
2.4.16.01. Toxin CsEv3 2sn3 Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.3 74 ± 17 -5.5
3.1.07.02. Juxtamembrane peptide (665-683) of protein gp41 1jau Human immunodeficiency virus type 1 Endosome 1 0 4.0 ± 4.2 86 ± 2 -8.0
3.1.23.01. Meucin-24 2kfe Mesobuthus eupeus Secreted 1 0 4.3 ± 3.5 82 ± 2 -7.5
2.1.01.01. Snake phospholipase A2 2i0u Vipera nikolskii Secreted 1 0 5.6 ± 0.9 88 ± 9 -15.2
2.3.06.04. Palmitoyl protein thioesterase 2 1pja Homo sapiens Lysosome 1 0 3.7 ± 1.6 60 ± 15 -4.6
1.2.32.01. Cytochrome P450 1n97 Thermus thermophilus Bact. Gram-neg inner 1 0 5.2 ± 0.3 43 ± 5 -9.9
2.1.01.01. Snake phospholipase A2, group II 1oz6 Echis carinatus Secreted 1 0 5.6 ± 1.0 84 ± 13 -9.6
3.1.15.01. Leucocin A, linear analogue 2ljt Leuconostoc gelidum Secreted 1 0 4.2 ± 2.8 81 ± 1 -6.6
2.2.41.05. Crotamine 1z99 Crotalus durissus terrificus Secreted 1 0 3.7 ± 0.8 26 ± 5 -5.6
2.1.16.01. Myelin basic protein 2lug Mus musculus Eukaryo. plasma 1 0 5.6 ± 1.5 79 ± 7 -10.3
2.1.03.01. Alpha-toxin (PHLC_CLOP1) 2wxu Clostridium perfringens Secreted 1 0 4.0 ± 0.9 85 ± 5 -7.0
3.1.05.03. Human platelet factor 4 based peptide, 56-70, modified 1djf Designed proteins Undefined 1 0 1.9 ± 1.4 87 ± 8 -4.9
2.1.02.01. Seed lipoxygenase-D 2iuk Glycine max Eukaryo. plasma 1 0 3.7 ± 1.7 85 ± 8 -6.2
2.3.06.07. Lipase, complex with foldase 2es4 Pseudomonas glumae Secreted 2 0 8.5 ± 0.0 65 ± 2 -7.2
3.2.05.02. Xanthomonin I 4nag Xanthomonas gardneri Secreted 1 0 8.7 ± 2.4 81 ± 11 -5.0
2.4.10.01. Synapsin I 1auv Bos taurus Vesicle 1 0 1.9 ± 1.1 86 ± 11 -5.2
2.2.34.01. Mu-conotoxin GS 1ag7 Conus geographus (Geography cone) Secreted 1 0 1.9 ± 1.0 68 ± 15 -2.6
3.1.03.05. Anchor helix of 1,2-diacylglycerol 3-glucosyltransferase 1z2t Acholeplasma laidlawii Bact. Gram-pos plas. 1 0 9.6 ± 1.6 90 ± 4 -13.7
2.1.01.01. Snake phospholipase A2, isoform 3 2osn Bungarus caeruleus Secreted 1 0 2.4 ± 0.6 84 ± 4 -5.8
2.4.28.01. Phenazine biosynthesis protein PhzF 1s7j Enterococcus faecalis Undefined 1 0 1.8 ± 0.7 77 ± 2 -4.3
2.3.18.01. Choline O-acetyltransferase, different conformation 1t1u Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 1.7 73 ± 15 -6.8
1.2.32.01. Cytochrome P450 2A13 2p85 Homo sapiens Endoplasm. reticulum 1 0 4.9 ± 0.4 47 ± 2 -10.0
2.2.34.04. Albumin 1 subunit B (Pab1) 1p8b Pisum sativum Secreted 1 0 11.1 ± 0.9 40 ± 13 -8.2
2.2.39.01. Weak tryptophan-containing neurotoxin 2mj0 Naja kaouthia Secreted 1 0 3.6 ± 1.7 57 ± 5 -5.9
2.1.18.01. Annexin XII 1dm5 Hydra vulgaris Eukaryo. plasma 3 0 2.7 ± 1.0 90 ± 7 -10.2
3.1.07.02. Envelope glycoprotein gp41 2x7r Human immunodeficiency virus type 1 Viral 3 0 5.5 ± 1.1 0 ± 10 -10.9
3.1.20.01. Alpha-conotoxin ImI 1e75 Conus imperialis (Imperial cone) Secreted 1 0 1.9 ± 0.9 80 ± 15 -3.7
3.1.21.08. Moricin 2jr8 Manduca sexta Secreted 1 0 5.9 ± 1.6 75 ± 3 -11.5
3.1.05.03. LAK160-P12 2l9a Designed proteins Undefined 1 0 4.9 ± 3.1 87 ± 1 -6.7
2.2.20.01. Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 2da0 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 2.5 64 ± 20 -2.5
1.2.32.01. Cytochrome P450 1A1 4i8v Homo sapiens Endoplasm. reticulum 1 0 7.1 ± 1.0 64 ± 3 -15.1
2.2.41.02. Antihypertensive protein BDS-1 1bds Anemonia sulcata Secreted 1 0 5.6 ± 0.8 83 ± 9 -9.6
2.3.06.01. Acetylcholinesterase 4qww Bungarus fasciatus Secreted 1 0 2.0 ± 1.5 36 ± 32 -3.0
2.3.15.01. Electron transfer flavoprotein 1efp Paracoccus denitrificans Bact. Gram-neg inner 2 0 4.3 ± 1.1 90 ± 13 -4.8
2.2.20.01. Pleckstrin 1pls Homo sapiens Eukaryo. plasma 1 0 3.6 ± 2.0 61 ± 19 -3.8
2.1.21.01. Influenza virus matrix protein M1, structure 2 4pus Influenza virus Viral 2 0 2.3 ± 1.6 81 ± 3 -9.4
2.3.01.02. Dhurrinase 1v02 Sorghum bicolor Secreted 2 0 2.4 ± 0.5 89 ± 9 -5.1
1.3.25.01. Leukocidin F 1pvl Staphylococcus aureus Secreted 1 0 4.0 ± 3.2 47 ± 10 -3.7
3.2.05.02. Sphingopyxin I 5jqf Sphingopyxis alaskensis Undefined 1 0 1.7 ± 1.8 40 ± 16 -3.7
3.1.04.03. Viral protein R, peptide 52-96, dimer, different strain 1x9v Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.2 ± 0.7 86 ± 4 -8.6
2.4.04.01. Sphingomyelinase C 1zwx Listeria ivanovii Secreted 1 0 6.2 ± 0.5 55 ± 1 -10.1
2.4.16.01. Tau-theraphotoxin-Hs1a 2n9z Haplopelma schmidti Secreted 1 0 6.1 ± 1.3 68 ± 10 -5.6
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 436-456 1bts Homo sapiens Eukaryo. plasma 1 0 9.2 ± 0.3 84 ± 2 -14.8
2.1.55.01. Secretion factor PAS 2b8i Vibrio vulnificus Secreted 1 0 5.4 ± 1.5 72 ± 7 -5.7
2.2.23.01. Lipoprotein BamB, conformation 2 3p1l Escherichia coli Bact. Gram-neg outer 1 0 3.6 ± 2.8 89 ± 10 -6.4
2.3.14.01. Alpha-tocopherol transfer protein, open state 1oiz Homo sapiens Golgi 1 0 8.1 ± 1.0 64 ± 10 -17.6
2.1.42.01. Bacteriocin 2fu2 Streptococcus pyogenes Secreted 1 0 1.6 ± 1.1 77 ± 16 -3.7
3.1.02.16. Peptide 211-263 of YscU protein 2ml9 Yersinia pseudotuberculosis Bact. Gram-neg inner 1 0 2.9 ± 1.8 82 ± 5 -6.6
3.1.02.02. Voltage sensor of calcium-activated potassium channel 2k44 Homo sapiens Eukaryo. plasma 1 0 7.5 ± 3.0 54 ± 4 -9.8
2.3.13.04. Glutathione peroxidase 8 3kij Homo sapiens Endoplasm. reticulum 1 0 3.4 ± 2.7 56 ± 16 -6.1
3.2.03.01. Hepcidin, structure 2 1m4f Homo sapiens Secreted 1 0 5.9 ± 1.2 76 ± 18 -6.4
1.2.42.01. Sphingomyelin phosphodiesterase 5i85 Homo sapiens Secreted 1 0 7.1 ± 1.4 53 ± 2 -9.2
2.2.20.02. Disabled homolog 1 1nu2 Mus musculus Eukaryo. plasma 1 0 14.8 ± 1.1 46 ± 12 -17.6
2.3.15.01. Electron transfer flavoprotein 1efv Homo sapiens Mitochon. inner 2 0 4.6 ± 1.3 79 ± 12 -4.6
1.2.19.01. Mitochondrial import receptor subunit TOM20, 51-145, with presequence peptide 1om2 Rattus norvegicus Mitochon. outer 2 0 2.9 ± 2.7 76 ± 7 -4.8
2.1.60.01. Aurelin 2lg4 Aurelia aurita Secreted 1 0 2.0 ± 0.9 50 ± 6 -4.4
3.1.03.09. Peptide (2-11) of ADP-ribosylation factor 6, in micelle 2bau Homo sapiens Eukaryo. plasma 1 0 11.2 ± 0.9 22 ± 4 -9.1
2.1.14.01. Peroxisome targeting signal 1 receptor PEX5 1hxi Trypanosoma brucei Peroxisome 1 0 3.7 ± 1.0 71 ± 5 -8.1
2.2.41.04. Antimicrobial peptide LCI 2b9k Bacillus subtilis Secreted 1 0 1.6 ± 2.9 89 ± 19 -4.4
1.1.26.07. STAS domain of sulfate permease 4dgh Vibrio cholerae Bact. Gram-neg inner 1 0 4.6 ± 0.6 33 ± 2 -6.2
2.1.58.01. Serine/threonine-protein kinase pelle 1ik7 Drosophila melanogaster Eukaryo. plasma 1 0 1.5 ± 3.7 86 ± 0 -6.8
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), structure 2 5fsa Candida albicans Endoplasm. reticulum 1 0 9.0 ± 0.8 61 ± 2 -18.0
2.1.15.02. Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) 1dvp Drosophila melanogaster Endosome 2 0 3.0 ± 0.0 89 ± 0 -6.6
2.4.16.02. Phormicin 1ica Protophormia terraenovae (Northern blowfly) Secreted 1 0 3.7 ± 2.3 90 ± 23 -5.0
2.1.56.01. PALS1-associated tight junction protein 1vf6 Homo sapiens Eukaryo. plasma 2 0 5.8 ± 0.4 53 ± 2 -9.4
2.1.08.01. Cytochrome c6 1f1f Arthrospira maxima Thylakoid 1 0 4.8 ± 1.6 80 ± 15 -3.5
2.4.11.01. Viscotoxin A3 1okh Viscum album Secreted 1 0 4.6 ± 1.3 32 ± 19 -4.9
2.2.36.01. Lactococcin 972 2lgn Lactococcus lactis Secreted 1 0 1.7 ± 2.8 56 ± 9 -3.3
1.2.54.01. Dihydroorotate dehydrogenase, structure 2 4cq8 Plasmodium falciparum Mitochon. inner 1 0 4.9 ± 0.4 52 ± 1 -12.0
2.1.23.01. Ectatomin 1eci Ectatomma tuberculatum Secreted 2 0 5.3 ± 1.8 58 ± 15 -5.2
1.2.03.08. HLA class II histocompatibility antigen, DM alpha chain 2bc4 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 0.7 21 ± 3 -4.7
2.1.21.03. Matrix protein p15 1mn8 Moloney murine leukemia virus Endosome 1 0 1.5 ± 1.8 65 ± 24 -3.5
2.1.19.01. Antifungal peptide 2l2r Echinochloa crus-galli Secreted 1 0 3.4 ± 1.5 50 ± 8 -3.8
1.1.56.01. Inner membrane protein YejM, strain K12 5i5h Salmonella typhimurium Bact. Gram-neg inner 1 0 1.1 ± 1.6 65 ± 2 -3.6
2.1.24.01. Pulmonary surfactant-associated protein B fragments 2dwf Homo sapiens Secreted 1 0 5.6 ± 1.3 77 ± 4 -9.5
2.3.31.01. Sorbose-specific phosphotransferase enzyme IIB component 1nrz Klebsiella pneumoniae Bact. Gram-neg inner 1 0 2.1 ± 0.7 83 ± 3 -4.5
2.4.07.01. PX domain of C2alpha-PI3 kinase 2ar5 Homo sapiens Eukaryo. plasma 1 0 5.6 ± 0.9 83 ± 17 -3.7
2.2.06.02. Prostaglandin-H2 D-isomerase, ligand-bound 3o22 Homo sapiens Endoplasm. reticulum 1 0 0.7 ± 1.2 78 ± 13 -2.4
2.1.01.01. Phospholipase A2, group IIA 1n28 Homo sapiens Secreted 1 0 3.6 ± 0.6 88 ± 4 -7.0
3.4.01.01. Contryphan-In 2m6d Conus inscriptus Secreted 1 0 8.2 ± 1.0 57 ± 15 -5.8
1.2.03.02. Hepatitis A virus cellular receptor 2 5f71 Homo sapiens Eukaryo. plasma 1 0 4.0 ± 2.0 63 ± 7 -5.3
3.1.03.02. Serine/threonine-protein kinase TOR1, FATC domain 2kit Saccharomyces cerevisiae Vacuole 1 0 6.3 ± 1.0 87 ± 18 -6.4
3.1.11.02. Pituitary adenylate cyclase activating polypeptide (PACAP)-38 2d2p Homo sapiens Secreted 1 0 3.9 ± 4.0 90 ± 0 -6.8
3.1.26.01. Piscidin 1 2ojm Morone saxatilis Secreted 1 0 10.6 ± 1.0 82 ± 13 -16.3
3.1.29.01. LL-37-derived peptide 2l5m Designed proteins Undefined 1 0 6.1 ± 1.0 89 ± 7 -9.7
2.2.11.01. E3 ubiquitin-protein ligase SMURF2 2jqz Homo sapiens Eukaryo. plasma 1 0 4.2 ± 1.8 23 ± 17 -5.6
1.2.32.01. Cytochrome P450 2R1 3czh Homo sapiens Endoplasm. reticulum 1 0 8.3 ± 1.5 48 ± 13 -13.2
2.2.34.11. Kalata B1, segment 93-120 1nb1 Oldenlandia affinis Secreted 1 0 5.3 ± 1.4 81 ± 18 -5.5
2.1.60.03. Pseudecin, conformation 2 2epf Pseudechis porphyriacus Secreted 1 0 5.4 ± 1.1 86 ± 1 -4.6
2.2.11.01. Protein kinase C alpha, complex with phosphatidyl serine 1dsy Rattus norvegicus Eukaryo. plasma 1 0 0.9 ± 1.5 18 ± 16 -3.0
2.2.12.04. AP-2 complex 2vj0 Rattus norvegicus Vesicle 1 0 2.6 ± 2.0 80 ± 11 -4.8
2.2.34.02. Delta-amaurobitoxin-Pl1b 1v91 Pireneitega luctuosa (Tangled nest spider) Secreted 1 0 2.4 ± 0.9 35 ± 4 -5.7
1.2.06.01. Spore surface protein Bcla 1wck Bacillus anthracis Bact. Gram-pos plas. 3 0 3.3 ± 0.2 8 ± 5 -8.9
2.3.06.09. Cutinase 1 3dcn Colletotrichum gloeosporioides Secreted 1 0 5.7 ± 1.2 44 ± 8 -10.1
2.3.22.02. NrdI protein 2x2o Bacillus cereus Undefined 1 0 3.6 ± 0.5 77 ± 4 -4.6
2.3.06.01. Acetylcholinesterase 4ey4 Homo sapiens Eukaryo. plasma 1 0 3.2 ± 0.5 33 ± 2 -8.4
2.3.06.15. Polyneuridine-aldehyde esterase 2wfm Rauvolfia serpentina (Serpentwood) Endoplasm. reticulum 1 0 2.5 ± 1.7 88 ± 3 -4.6
2.4.16.02. Sapecin 1l4v Sarcophaga peregrina Secreted 1 0 5.4 ± 1.5 84 ± 18 -5.1
3.1.29.01. Fowlicidin-2 2gdl Gallus gallus Secreted 1 0 3.1 ± 0.5 85 ± 4 -8.9
2.1.20.01. Coagulation factor XIV (protein C) in complex with its receptor 1lqv Homo sapiens Eukaryo. plasma 2 0 3.4 ± 3.9 53 ± 14 -5.6
3.2.08.01. Amyloid beta A4 protein, peptide 688-707 5hoy Homo sapiens Eukaryo. plasma 3 0 6.0 ± 1.0 89 ± 0 -5.7
1.2.43.03. Envelope glycoprotein B 3nw8 Human herpesvirus Viral 3 0 4.6 ± 0.0 1 ± 1 -11.7
3.1.11.01. Neuropeptide F 1k8v Moniezia expansa (Sheep tapeworm) Secreted 1 0 2.9 ± 1.1 68 ± 9 -7.0
2.2.27.01. C1 domain of protein kinase C theta 4fkd Mus musculus Eukaryo. plasma 1 0 3.6 ± 0.4 35 ± 2 -8.0
2.1.01.01. Phospholipase A2, beta bungarotoxin A1 chain, complex with bungarotoxin 1bun Bungarus multicinctus Secreted 2 0 1.7 ± 0.9 79 ± 3 -3.8
3.2.05.02. Microcin J25, redesigned, version 1 2mmt Designed proteins Undefined 1 0 3.0 ± 0.9 90 ± 5 -5.2
1.2.03.02. Hepatitis A virus cellular receptor 1 homolog 2or8 Mus musculus Eukaryo. plasma 1 0 4.2 ± 2.4 51 ± 16 -3.9
2.3.06.03. Gastric lipase, closed state 1hlg Homo sapiens Secreted 1 0 3.2 ± 1.4 6 ± 12 -5.6
2.3.06.01. Carboxylic ester hydrolase, closed state 4be4 Ophiostoma piceae Secreted 1 0 6.4 ± 2.3 61 ± 4 -5.7
2.2.06.02. Muscle fatty acid binding protein 1bwy Bos taurus Eukaryo. plasma 1 0 4.8 ± 1.3 71 ± 12 -6.6
1.2.45.02. Small hydrophobic protein, peptide 1-14 2nb7 Human respiratory syncytial virus Viral 1 0 4.1 ± 0.9 84 ± 6 -7.7
3.2.08.01. Peptide 35-42, alternate polymorph I 2y3k Homo sapiens Secreted 2 0 3.4 ± 1.4 89 ± 4 -7.2
2.4.11.01. Beta-hordothionin 1wuw Hordeum vulgare Secreted 1 0 3.6 ± 1.1 55 ± 15 -5.4
3.2.11.01. Anti-inflammatory peptide 5vav Designed proteins Undefined 1 0 7.7 ± 0.8 63 ± 12 -9.0
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4 3b7y Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.5 9 ± 6 -4.1
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 6 4coh Trypanosoma cruzi Endoplasm. reticulum 1 0 6.3 ± 1.3 56 ± 6 -7.3
3.1.17.01. Antimicrobial peptide HP 1p0l Helicobacter pylori Secreted 1 0 5.3 ± 0.6 79 ± 9 -10.5
2.4.16.04. Defensin-like protein 2 2n2r Raphanus sativus Secreted 1 0 2.5 ± 1.7 31 ± 24 -4.2
2.1.32.01. Alpha-synuclein 1xq8 Homo sapiens Eukaryo. plasma 1 0 8.7 ± 1.1 87 ± 4 -15.7
2.2.52.01. Allene oxide cyclase 2 2brj Arabidopsis thaliana Chloroplast inner 3 0 2.6 ± 0.5 88 ± 5 -9.7
2.1.14.02. SusD superfamily protein 3myv Bacteroides vulgatus Secreted 1 0 4.0 ± 1.0 64 ± 2 -6.0
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 2 4axd Arabidopsis thaliana Eukaryo. plasma 1 0 1.5 ± 0.1 88 ± 4 -4.0
3.1.02.10. Transmembrane emp24 domain-containing protein 10, peptide 207-219 1m23 Oryctolagus cuniculus Golgi 1 0 4.9 ± 3.2 66 ± 3 -6.9
2.2.41.01. Neutrophil defensin 1 2pm1 Homo sapiens Secreted 1 0 3.6 ± 1.3 85 ± 6 -3.8
1.2.01.01. Macrophage colony-stimulating factor 1 receptor 3bea Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.5 54 ± 19 -4.2
3.4.02.02. Mersacidin, structure in methanol solution 1mqx Bacillus sp. Secreted 1 0 1.9 ± 1.3 87 ± 15 -2.9
1.2.39.02. Matrilysin, structure 3 2mzh Homo sapiens Secreted 1 0 2.2 ± 1.6 67 ± 22 -6.4
2.2.11.01. Protein unc-13 homolog A, C2A domain 2cjs Rattus norvegicus Eukaryo. plasma 1 0 3.5 ± 2.0 47 ± 12 -5.0
2.3.18.01. Carnitine O-acetyltransferase, complex with substrate 2h3u Mus musculus Mitochon. inner 1 0 3.0 ± 1.0 87 ± 3 -5.9
1.2.22.01. Apoptosis regulator BAX 1f16 Homo sapiens Mitochon. outer 1 0 4.3 ± 0.8 84 ± 5 -4.2
3.1.19.01. Paracelsin X 4by8 Trichoderma reesei Secreted 1 0 14.6 ± 5.1 60 ± 4 -14.6
2.3.06.02. Antigen 85c, conformation 3 1dqy Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 5.1 ± 1.2 17 ± 3 -6.1
3.1.28.06. Magainin 2, Ala-analogue 4mgp Designed proteins Secreted 1 0 10.0 ± 4.1 79 ± 2 -15.1
2.2.26.01. LM-5 FYVE domain 1z2q Leishmania major Endosome 1 0 1.5 ± 1.5 22 ± 19 -3.4
3.1.28.04. Phylloseptin-1 2jq0 Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 9.5 ± 1.4 76 ± 7 -13.5
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 1 2xar Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 1.6 69 ± 7 -6.1
1.2.32.01. Cytochrome P450 120a1, different conformation 2ve3 Synechocystis sp. Thylakoid 1 0 5.2 ± 1.5 52 ± 15 -6.8
2.2.08.01. Osmotin 1pcv Nicotiana tabacum Secreted 1 0 2.4 ± 1.9 82 ± 19 -2.7
2.2.39.01. Ancestral Mamba toxin 1 5mg9 Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 4.2 ± 1.2 49 ± 6 -8.0
2.3.05.02. Type II NADH:ubiquinone oxidoreductase 5jwa Plasmodium falciparum Mitochon. inner 2 0 7.6 ± 0.0 90 ± 0 -11.3
2.1.01.01. Snake phospholipase A2, group I, acidic 2 1m8t Ophiophagus hannah Secreted 1 0 4.4 ± 0.8 88 ± 6 -6.6
1.2.55.01. Neutral ceramidase, structure 2 2zxc Pseudomonas aeruginosa Secreted 1 0 4.6 ± 1.7 71 ± 8 -7.6
3.1.07.02. Juxtamembrane peptide (662-683) of protein gp160 4g6f Human immunodeficiency virus type 1 Endosome 1 0 4.9 ± 1.4 86 ± 0 -5.0
3.4.02.06. Epilancin 15X 1w9n Staphylococcus epidermidis Secreted 1 0 2.9 ± 1.0 72 ± 7 -5.0
3.2.02.02. T-2-conotoxin MrIA 2ew4 Conus marmoreus Secreted 1 0 2.5 ± 1.5 81 ± 19 -3.0
2.2.27.01. C1 domain of protein kinase C delta 2yuu Homo sapiens Nuclear outer 1 0 4.0 ± 0.9 77 ± 20 -6.5
1.2.56.01. Fatty aldehyde dehydrogenase 4qgk Homo sapiens Endoplasm. reticulum 2 0 3.5 ± 1.9 83 ± 7 -6.5
2.2.06.01. Epididymal-specific lipocalin-5 1epb Rattus norvegicus Secreted 1 0 6.4 ± 1.1 74 ± 4 -3.8
3.4.12.01. Actinomycin X2 1qfi Streptomyces antibioticus Secreted 1 0 15.2 ± 2.3 35 ± 34 -14.1
2.2.11.01. C2 domain of abscisic acid-related protein CAR4 5a52 Arabidopsis thaliana Eukaryo. plasma 2 0 3.9 ± 0.7 82 ± 11 -6.6
3.1.33.01. Stage V sporulation protein M 2mvh Bacillus subtilis Vacuole 1 0 6.3 ± 1.0 90 ± 4 -9.9
2.4.17.01. Vitellogenin 1lsh Ichthyomyzon unicuspus (Silver lamprey) Secreted 1 0 3.4 ± 1.3 81 ± 0 -4.6
2.1.02.01. Arachidonate 15-lipoxygenase 5med Synechococcus sp. Bact. Gram-neg inner 1 0 3.3 ± 1.6 75 ± 7 -7.4
2.4.07.01. Sorting nexin-11, conformation 2 4ikd Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.2 58 ± 4 -5.3
2.3.06.05. Copper inducible hydrolase YahD 3og9 Lactococcus lactis Bact. Gram-pos plas. 1 0 1.4 ± 1.1 33 ± 10 -4.0
2.1.01.01. Snake phospholipase A2, acidic, group II 1ijl Agkistrodon acutus Secreted 1 0 4.2 ± 1.2 83 ± 12 -7.5
2.3.24.02. Predicted hydrolase 3mpo Lactobacillus brevis Undefined 1 0 3.6 ± 0.0 83 ± 7 -5.7
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 2 3mdm Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 1.3 51 ± 8 -5.9
2.2.34.02. omega-Agatoxin 1agg Agelenopsis aperta Secreted 1 0 2.5 ± 1.4 57 ± 17 -5.0
3.1.11.01. Neuropeptide Y analogue 1icy Sus scrofa Secreted 1 0 6.4 ± 0.5 69 ± 6 -8.1
2.2.19.01. Adsorption protein p2 1n7v Bacteriophage prd1 Viral 1 0 8.7 ± 0.4 81 ± 1 -8.6
3.1.20.01. Alpha-conotoxin EIVA 1pqr Conus ermineus Secreted 1 0 2.5 ± 1.3 14 ± 14 -3.4
2.2.11.01. Extended synaptotagmin-2, two first C2 domains 4npk Homo sapiens Eukaryo. plasma 1 0 3.8 ± 2.8 56 ± 9 -4.5
2.2.34.11. Vodo peptide N 2aks Viola odorata Secreted 1 0 4.0 ± 1.4 89 ± 22 -6.7
2.1.46.01. Protein yciE 3ogh Escherichia coli Undefined 2 0 4.0 ± 1.0 88 ± 4 -9.7
1.2.32.01. Cytochrome P450 2D6, conformation 3 3qm4 Homo sapiens Endoplasm. reticulum 1 0 9.0 ± 1.4 35 ± 11 -9.3
2.2.39.01. Cardiotoxin III (cytotoxin 3) 1h0j Naja atra Secreted 1 0 7.1 ± 0.9 59 ± 7 -11.3
3.2.01.07. Protegrin-3, dimer 2mz6 Sus scrofa Secreted 2 0 0.4 ± 2.1 89 ± 2 -2.3
2.2.05.01. Pseudoazurin 1pmy Methylobacterium extorquens Bact. Gram-neg inner 1 0 1.6 ± 1.4 45 ± 13 -4.3
2.1.21.02. Matrix protein p10 2f76 Mason-Pfizer monkey virus Viral 1 0 3.9 ± 1.2 48 ± 5 -5.8
3.2.06.01. Growth-blocking peptide 2djc Spodoptera litura Secreted 1 0 2.9 ± 2.0 19 ± 14 -3.1
1.2.38.03. Endo-type membrane-bound lytic murein transglycosylase A 2y8p Escherichia coli Bact. Gram-neg outer 1 0 0.0 ± 3.6 86 ± 15 -2.2
2.2.20.01. Dynamin-2 2ys1 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 0.4 49 ± 3 -5.3
2.2.12.01. Lymphocyte antigen 86 3mtx Gallus gallus Secreted 1 0 2.3 ± 1.6 69 ± 11 -2.4
2.3.06.18. Protein lpg2422 4m0m Legionella pneumophila Undefined 1 0 4.6 ± 2.9 76 ± 6 -6.9
1.2.30.01. Potassium voltage-gated channel subfamily E member 1 2k21 Homo sapiens Eukaryo. plasma 1 0 12.1 ± 0.4 54 ± 2 -24.7
1.2.53.01. Squalene synthase, conformation 2 3wcf Homo sapiens Endoplasm. reticulum 1 0 2.8 ± 0.8 87 ± 3 -7.0
2.3.06.19. Lipase A 1isp Bacillus subtilis Secreted 1 0 1.9 ± 0.8 59 ± 12 -5.2
2.3.01.06. Glycosyl hydrolase PslG 5bxa Pseudomonas aeruginosa Secreted 1 0 6.0 ± 1.2 72 ± 9 -6.9
2.2.06.02. Cellular retinol-binding protein II 1kqw Danio rerio Eukaryo. plasma 1 0 3.1 ± 1.3 45 ± 13 -4.9
1.2.43.01. Envelope glycoprotein, West Nile virus, structure 4 3iyw West Nile virus Viral 1 0 6.6 ± 2.9 30 ± 15 -4.5
2.1.52.01. Pheromone binding protein 1ow4 Rhyparobia maderae (Madeira cockroach) Secreted 1 0 4.4 ± 0.8 30 ± 16 -4.4
2.2.45.01. Outer membrane protein IcsA autotransporter 3ml3 Shigella flexneri Bact. Gram-neg outer 1 0 3.4 ± 0.5 65 ± 2 -6.2
2.4.16.01. Alpha-mammal toxin BmK-M8 1snb Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.4 ± 2.4 79 ± 22 -2.3
2.2.06.02. Fatty acid binding protein 6, ileal (Gastrotropin) 3elz Danio rerio Eukaryo. plasma 1 0 1.1 ± 0.9 85 ± 6 -2.4
3.1.19.01. Cephaibol A 1ob4 Acremonium tubakii Secreted 1 0 14.1 ± 2.5 58 ± 18 -14.7
1.3.25.01. LukGH complex 5k59 Staphylococcus aureus Secreted 2 0 4.7 ± 2.8 41 ± 15 -5.4
2.2.20.01. Son of sevenless homolog 1 (two domains) 1dbh Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.8 28 ± 19 -4.2
1.2.50.01. Fragaceatoxin C, trimer 3zwj Actinia fragacea (Strawberry anemone) Secreted 3 0 2.4 ± 0.2 89 ± 4 -8.4
2.2.06.02. Intestinal fatty acid binding protein, structure 2 3akm Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.1 46 ± 8 -4.4
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 2 1zhy Saccharomyces cerevisiae Golgi 1 0 0.9 ± 0.4 87 ± 4 -4.7
3.2.01.07. Protegrin-1 1pg1 Sus scrofa Secreted 1 0 2.2 ± 0.4 72 ± 4 -4.2
1.2.04.01. Integrin beta-3/alpha-V complex 3ije Homo sapiens Eukaryo. plasma 2 0 6.1 ± 2.1 13 ± 14 -9.0
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1aod Listeria monocytogenes Secreted 1 0 7.4 ± 1.0 79 ± 10 -9.2
2.2.20.01. PH domain of docking protein 2 2d9w Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.2 13 ± 17 -3.5
2.3.15.02. FAD synthase 2wsi Saccharomyces cerevisiae Mitochon. inner 1 0 3.3 ± 1.7 65 ± 17 -4.0
1.2.32.01. Cytochrome P450 3A4, conformation 3 5te8 Homo sapiens Endoplasm. reticulum 1 0 4.4 ± 1.6 62 ± 5 -13.6
2.3.06.06. Lipase 2 1thg Geotrichum candidum Secreted 1 0 6.4 ± 1.7 23 ± 14 -4.7
2.2.34.02. beta-TRTX-Pre1a toxin 5i1x Psalmopoeus cambridgei (Trinidad chevron tarantula) Secreted 1 0 5.0 ± 1.6 52 ± 12 -6.3
2.2.06.02. Myelin P2 protein 1yiv Equus caballus Eukaryo. plasma 1 0 1.3 ± 1.7 53 ± 11 -4.8
2.2.39.01. Cardiotoxin-A5 1kxi Naja atra Secreted 1 0 6.3 ± 1.1 69 ± 15 -10.5
2.4.16.04. Flower-specific defensin, dimer 4cqk Nicotiana alata (Winged tobacco) Secreted 2 0 3.7 ± 1.2 79 ± 9 -6.3
2.4.16.03. Chlorotoxin 1chl Leiurus quinquestriatus quinquestriatus Secreted 1 0 6.5 ± 1.2 87 ± 14 -4.3
2.3.06.07. Thermostable lipase 2dsn Geobacillus zalihae Secreted 1 0 4.9 ± 0.9 32 ± 3 -7.7
2.2.12.01. Ganglioside GM2 activator, different conformation 1pub Homo sapiens Lysosome 1 0 4.9 ± 0.7 50 ± 8 -7.3
2.4.06.04. STAR-related bacterial protein 2d4r Thermus thermophilus Bact. Gram-neg inner 1 0 6.9 ± 2.2 28 ± 6 -7.1
2.1.01.01. Snake phospholipase A2, group I, isoform 2 1u4j Bungarus caeruleus Secreted 1 0 2.2 ± 0.6 83 ± 4 -8.5
2.4.16.02. Lucifensin 2lld Lucilia sericata Secreted 1 0 1.1 ± 1.7 11 ± 12 -3.0
1.2.46.01. Agnoprotein (1-71) 5nhq JC polyomavirus Endosome 1 0 7.0 ± 2.1 84 ± 3 -11.8
3.2.01.01. Arenicin-2, dimer 2l8x Arenicola marina Secreted 2 0 2.7 ± 1.1 87 ± 4 -4.0
2.2.07.01. Lipocalin BcnB 5ixg Burkholderia cepacia Bact. Gram-neg inner 1 0 2.0 ± 1.0 36 ± 5 -3.9
2.1.03.01. Alpha-toxin (PHLC_CLOP1) , different conformation 1qmd Clostridium perfringens Secreted 1 0 4.8 ± 1.0 80 ± 8 -6.7
3.1.03.03. Anticancer peptide designed based on the helix of phosphotransferase IIA 1vm2 Designed proteins Undefined 1 0 7.0 ± 1.8 78 ± 15 -12.0
2.1.02.01. Seed lipoxygenase-B 2iuj Glycine max Eukaryo. plasma 1 0 1.7 ± 3.0 51 ± 15 -4.8
2.3.16.05. ATPase Get3, homodimer 3a36 Saccharomyces cerevisiae Endoplasm. reticulum 2 0 5.6 ± 3.0 66 ± 10 -6.6
2.2.06.01. Retinol binding protein 1kt6 Bos taurus Secreted 1 0 4.3 ± 1.7 74 ± 12 -4.7
2.1.25.03. Enterocin 7A 2m5z Enterococcus faecalis Secreted 0 0 4.4 ± 0.3 57 ± 3 -5.3
2.3.08.02. Cytosolic phospholipase A2, group IVA 1cjy Homo sapiens Vesicle 1 0 5.8 ± 1.0 70 ± 9 -9.9
2.2.34.01. Conotoxin TVIIA 1eyo Conus tulipa (Fish-hunting cone snail) Secreted 1 0 2.2 ± 0.7 74 ± 9 -4.6
1.2.32.01. Fatty-acid peroxygenase 1izo Bacillus subtilis Bact. Gram-pos plas. 1 0 1.2 ± 0.3 76 ± 1 -5.5
2.1.01.01. Snake phospholipase A2, acidic 2h4c Daboia russellii siamensis Secreted 1 0 5.7 ± 1.1 88 ± 10 -9.0
2.2.48.01. Hypothetical molybdopterin biosynthesis MoeA protein 1uz5 Pyrococcus horikoshii Undefined 1 0 4.7 ± 1.7 79 ± 2 -5.0
1.2.32.01. Cytochrome P450 2B4, open state 3 3r1b Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.7 ± 0.0 43 ± 5 -9.8
2.4.16.01. Neurotoxin 2 1jza Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.7 68 ± 15 -5.6
3.2.05.02. Caulonodin 2mlj Caulobacter sp. Secreted 1 0 2.4 ± 1.7 87 ± 15 -5.0
2.1.18.01. Annexin 24 1dk5 Capsicum annuum Eukaryo. plasma 1 0 3.5 ± 1.3 76 ± 18 -4.4
3.1.07.04. Envelope glycoprotein E1, heterodimerization peptide (350-370) 1emz Hepatitis C virus Viral 1 0 6.2 ± 0.2 86 ± 9 -8.5
3.1.20.01. Alpha-conotoxin GIA 1not Conus geographus (Geography cone) Secreted 1 0 1.6 ± 1.5 89 ± 20 -2.3
3.1.12.01. Endothelin-1 3cmh Rattus norvegicus Secreted 1 0 6.3 ± 3.9 72 ± 40 -4.8
3.1.04.07. Peptide (2-25) of antifreeze protein Afp1 2lq0 Glaciozyma antarctica Undefined 1 0 4.0 ± 3.8 85 ± 2 -9.5
2.2.20.01. Pleckstrin homology domain-containing family B member 2 2dhi Mus musculus Eukaryo. plasma 1 0 0.6 ± 1.5 86 ± 14 -2.8
2.3.14.01. Phosphatidylinositol transfer protein PDR16 4fmm Saccharomyces cerevisiae Endoplasm. reticulum 1 0 9.9 ± 2.6 78 ± 19 -13.9
2.2.41.02. Sea anemone neurotoxin-1 1shi Stoichactis helianthus Secreted 1 0 8.0 ± 1.0 87 ± 17 -5.9
2.3.06.09. Cutinase 4oyy Humicola insolens (Soft-rot fungus) Secreted 1 0 4.9 ± 1.4 46 ± 6 -10.0
2.3.16.01. Shikimate kinase 1e6c Erwinia chrysanthemi Bact. Gram-neg inner 2 0 2.6 ± 1.8 90 ± 12 -5.8
2.2.20.01. T-lymphoma invasion and metastasis-inducing protein 1, with G-protein RAC2 1foe Mus musculus Eukaryo. plasma 2 0 4.5 ± 1.1 64 ± 7 -6.7
1.2.43.01. Envelope glycoprotein, West Nile virus, structure 1 2hg0 West Nile virus Viral 1 0 4.8 ± 2.6 44 ± 4 -4.3
2.3.01.02. Beta-glucosidase 6 3gnr Oryza sativa (Rice) Secreted 1 0 4.8 ± 0.2 80 ± 1 -12.4
2.4.05.02. SDS hydrolase SdsA1 2cfu Pseudomonas aeruginosa Secreted 1 0 6.0 ± 2.5 70 ± 4 -7.0
3.4.04.03. Tridecaptin A1 2n5y Designed proteins Undefined 1 0 2.1 ± 1.0 89 ± 7 -3.9
2.1.39.01. Viral protein R, full length 1m8l Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 4.7 ± 2.8 64 ± 36 -4.0
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 4 3zg2 Trypanosoma cruzi Endoplasm. reticulum 1 0 5.8 ± 1.0 62 ± 4 -9.0
2.4.11.01. Crambin 1ejg Crambe abyssinica Secreted 1 0 4.0 ± 1.7 79 ± 15 -7.0
2.3.06.12. Lipase/esterase 3bjr Lactobacillus plantarum Secreted 1 0 2.1 ± 0.2 72 ± 5 -7.0
2.3.06.01. Acetylcholinesterase 1ea5 Torpedo californica Eukaryo. plasma 1 0 1.8 ± 1.1 34 ± 5 -4.7
2.2.21.05. Kunitz-type proteinase inhibitor BbCI 2gzb Bauhinia bauhinioides Secreted 1 0 7.9 ± 0.3 28 ± 3 -9.3
2.1.08.01. Quinohemoprotein alcohol dehydrogenase ADH IIB 1kv9 Pseudomonas putida Bact. Gram-neg outer 1 0 1.7 ± 1.1 77 ± 22 -5.9
2.4.13.01. Oxysterol-binding protein homolog 4 (KES1), N-terminal helix removed 1zi7 Saccharomyces cerevisiae Golgi 1 0 2.5 ± 0.5 75 ± 8 -6.9
2.1.42.01. PapB 2ip6 Pediococcus pentosaceus Secreted 1 0 0.6 ± 2.6 72 ± 23 -2.2
3.1.02.09. Peptide (659-711) of platelet endothelial cell adhesion molecule 2ky5 Homo sapiens Eukaryo. plasma 1 0 1.0 ± 3.8 89 ± 3 -3.7
3.2.04.01. Cyclic trypsin inhibitor STFI-1, permutant 1o8y Helianthus annuus Secreted 1 0 3.4 ± 1.3 83 ± 18 -6.0
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3a 5fc1 Mus musculus Secreted 1 0 2.3 ± 3.0 62 ± 17 -4.8
2.3.16.04. Dynamin-like protein 2j69 Nostoc punctiforme Bact. Gram-neg inner 1 0 4.0 ± 7.0 15 ± 10 -5.5
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1t27 Rattus norvegicus Eukaryo. plasma 1 0 2.3 ± 1.9 12 ± 12 -4.1
2.3.11.01. Ferrochelatase, conformation 1 1hrk Homo sapiens Mitochon. inner 2 0 2.7 ± 0.1 90 ± 0 -9.9
1.2.19.01. Mitochondrial import receptor subunit TOM20, 59-126, with presequence peptide 3awr Rattus norvegicus Mitochon. outer 2 0 5.0 ± 2.6 32 ± 7 -4.1
2.4.16.05. Eurocin 2lt8 Eurotium amstelodami Secreted 1 0 5.3 ± 1.3 84 ± 12 -5.5
3.1.03.09. Peptide (2-11) of ADP-ribosylation factor 6, in aqueous solution 2bao Homo sapiens Eukaryo. plasma 1 0 8.0 ± 1.2 82 ± 8 -5.5
1.2.54.01. Glycolate oxidase 1gox Spinacia oleracea Peroxisome 4 0 4.1 ± 0.0 90 ± 0 -18.5
3.1.15.01. Curvacin-A 2a2b Lactobacillus curvatus Secreted 1 0 2.5 ± 1.3 34 ± 18 -6.7
1.1.26.07. STAS domain of sulfate permease 4dgf Wolinella succinogenes Bact. Gram-neg inner 1 0 2.6 ± 0.5 51 ± 2 -7.0
1.2.03.07. Netrin receptor UNC5B 3g5b Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 2.5 90 ± 14 -8.5
2.4.07.01. PX domain of NADH oxidase (p40phox), ligand-bound 1h6h Homo sapiens Endosome 1 0 3.9 ± 2.0 55 ± 14 -6.0
2.2.28.01. Tachycitin 1dqc Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 4.5 ± 0.8 78 ± 8 -5.6
2.3.16.07. Ras-related protein Rab-9A 1wms Homo sapiens Eukaryo. plasma 1 0 1.9 ± 0.8 48 ± 7 -5.0
2.1.08.01. Cytochrome c6 1ls9 Cladophora glomerata Thylakoid 1 0 4.1 ± 1.0 70 ± 14 -2.9
2.4.11.01. Viscotoxin B 1jmp Viscum album Secreted 1 0 1.2 ± 1.4 52 ± 13 -3.2
2.1.19.01. Nigellin 2nb2 Nigella sativa Secreted 1 0 4.7 ± 2.2 69 ± 12 -4.4
2.1.13.01. Molt-inhibiting hormone 1j0t Marsupenaeus japonicus Secreted 1 0 4.1 ± 0.4 66 ± 6 -7.0
1.1.59.01. Membrane protease specific for a stomatin homolog, monomer 3bpp Pyrococcus horikoshii Archaebac. 1 0 4.0 ± 0.4 82 ± 5 -6.3
1.2.51.01. Bis(5-adenosyl)-triphosphatase ENPP4 4lqy Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 81 ± 12 -5.5
2.1.21.05. Matrix protein p15 1hek Equine infectious anemia virus Endosome 1 0 1.0 ± 2.8 76 ± 21 -2.6
2.2.33.01. Antimicrobial peptide 1b 2lb7 Triticum kiharae (Wheat) Secreted 1 0 2.2 ± 0.7 89 ± 7 -2.5
3.1.15.02. Plantaricin-A 1ytr Lactobacillus plantarum Secreted 1 0 9.0 ± 0.5 78 ± 10 -9.4
2.2.25.01. Superoxide dismutase [Cu-Zn] 1oal Photobacterium leiognathi Bact. Gram-neg inner 1 0 2.4 ± 0.9 77 ± 2 -6.8
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 2 2wx2 Trypanosoma cruzi Endoplasm. reticulum 1 0 5.9 ± 5.9 63 ± 2 -6.2
2.1.01.01. Phospholipase A2, group IB 1g4i Bos taurus Secreted 1 0 1.9 ± 0.5 87 ± 4 -7.4
3.4.01.01. Contryphan-Lo 2m6h Conus loroisii Secreted 1 0 3.3 ± 0.8 89 ± 14 -5.4
3.1.02.01. Fourth intracellular loop of CB1 cannabinoid receptor 2mz2 Designed proteins Eukaryo. plasma 1 0 6.3 ± 1.2 80 ± 6 -7.4
3.1.31.01. Dermcidin 2ksg Homo sapiens Secreted 1 0 4.7 ± 1.4 45 ± 6 -7.0
2.1.29.01. Apolipoprotein E 1ya9 Mus musculus Secreted 1 0 1.6 ± 1.4 85 ± 11 -4.1
3.1.05.01. Antimicrobial peptide RP-1 2rlg Designed proteins Undefined 1 0 5.9 ± 4.2 75 ± 4 -5.0
2.2.11.01. Protein unc-13 homolog A, C2C domain 3kwu Rattus norvegicus Eukaryo. plasma 1 0 3.3 ± 1.9 67 ± 16 -3.6
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 1 2q9f Homo sapiens Endoplasm. reticulum 1 0 2.8 ± 1.0 86 ± 7 -5.8
2.2.34.11. Cycloviolacin O1 1df6 Viola odorata Secreted 1 0 4.1 ± 1.2 63 ± 19 -5.9
2.1.60.03. Natrin-1 1xx5 Naja atra Secreted 1 0 2.6 ± 2.4 60 ± 49 -5.2
2.2.11.01. Synaptotagmin-1 1rsy Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 1.6 24 ± 17 -4.1
1.2.059.01. Serum paraoxonase/arylesterase 1 (PON1) 1v04 Homo sapiens Eukaryo. plasma 1 0 6.7 ± 0.2 61 ± 3 -9.7
1.2.17.02. Synaptobrevin homolog YKT6 3kyq Rattus norvegicus Vesicle 1 0 2.5 ± 2.0 53 ± 8 -4.9
2.2.34.02. U1-theraphotoxin-Hh1a 1i25 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.6 ± 0.2 79 ± 1 -5.1
2.2.47.01. Glycoside hydrolase family 9 protein 1wzx Clostridium thermocellum Bact. Gram-pos plas. 1 0 7.4 ± 2.0 77 ± 6 -4.1
2.3.06.09. Cutinase-like protein 2czq Cryptococcus sp. Secreted 1 0 4.9 ± 1.3 54 ± 16 -9.0
2.3.22.02. NrdI protein 2xod Bacillus anthracis Undefined 1 0 4.1 ± 0.4 72 ± 3 -4.8
2.3.06.13. Protein NDRG2 2qmq Mus musculus Eukaryo. plasma 1 0 8.3 ± 2.2 43 ± 14 -9.6
2.2.02.02. HCV serine protease NS3 3p8n Hepatitis C virus Endoplasm. reticulum 2 0 8.7 ± 1.7 56 ± 8 -9.9
2.4.16.04. Defensin-like protein 1 1ayj Raphanus sativus Secreted 1 0 11.0 ± 1.9 39 ± 19 -7.4
2.4.16.02. Coprisin 2ln4 Copris tripartitus Secreted 1 0 4.5 ± 0.6 42 ± 4 -5.3
2.2.06.02. Retinol-binding protein 2 1opb Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 1.4 25 ± 7 -3.6
1.2.43.04. Glycoprotein G, structure 1 5i2m Vesicular stomatitis virus Viral 3 0 6.3 ± 4.2 14 ± 8 -7.9
3.1.11.01. Peptide YY 1ru5 Sus scrofa Secreted 1 0 5.1 ± 1.2 83 ± 3 -5.3
2.2.11.01. Protein kinase C beta 3pfq Rattus norvegicus Eukaryo. plasma 1 0 2.6 ± 0.9 45 ± 5 -3.4
2.1.01.01. Phospholipase A2 homolog 1ppa Agkistridon piscivorus Secreted 1 0 1.2 ± 0.9 85 ± 8 -4.5
3.2.05.02. Microcin J25, redesigned, version 2 2mmw Designed proteins Undefined 1 0 2.6 ± 3.5 90 ± 4 -3.7
2.2.12.01. Lymphocyte antigen 96 2z64 Mus musculus Eukaryo. plasma 1 0 3.4 ± 1.1 66 ± 4 -7.0
2.3.06.03. Gastric lipase, open (active) state 1k8q Canis lupus familiaris Secreted 1 0 7.2 ± 0.5 78 ± 6 -12.6
2.3.06.17. Phosphatidylcholine-sterol acyltransferase, structure 2 4xwg Homo sapiens Secreted 1 0 3.7 ± 0.7 37 ± 4 -6.1
2.3.05.02. Sulfide-quinone reductase 3sx6 Acidithiobacillus ferrooxidans Bact. Gram-neg inner 1 0 10.6 ± 0.6 70 ± 8 -7.3
2.2.06.02. Intestinal fatty acid binding protein, structure 1 1icm Rattus norvegicus Eukaryo. plasma 1 0 3.5 ± 1.5 51 ± 18 -4.3
3.1.03.11. Toll/interleukin-1 receptor domain-containing adapter protein 5t7q Homo sapiens Eukaryo. plasma 1 0 4.6 ± 1.3 75 ± 6 -9.3
3.2.08.01. Peptide 35-42, alternate polymorph II 2y3l Homo sapiens Secreted 4 0 2.7 ± 1.4 78 ± 8 -6.0
1.2.17.01. SNARE complex with synaptotagmin1 2n1t Rattus norvegicus Eukaryo. plasma 5 0 2.6 ± 2.9 42 ± 16 -4.6
2.4.11.01. Viscotoxin A1 3c8p Viscum album Secreted 1 0 2.3 ± 0.9 45 ± 7 -4.9
2.4.08.01. Eosinophil cationic protein 1h1h Homo sapiens 1 0 3.5 ± 1.0 88 ± 6 -7.3
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4-like 2nsq Homo sapiens Eukaryo. plasma 1 0 1.8 ± 1.1 85 ± 5 -3.3
2.4.04.01. Type II inositol 1,4,5-trisphosphate 5-phosphatase 4cml Homo sapiens Endoplasm. reticulum 1 0 4.6 ± 1.1 48 ± 9 -5.1
3.1.11.01. Neuropeptide Y-pancreatic polypeptide hybrid 1tz4 Sus scrofa Secreted 1 0 5.1 ± 1.0 88 ± 8 -6.1
2.2.34.07. Asteropsin F 2n2g Asteropus sp. Secreted 1 0 4.3 ± 1.7 60 ± 11 -3.4
2.3.003.01. Gamma-ketol reductase 5a3v Arabidopsis thaliana Chloroplast inner 1 0 5.0 ± 0.6 89 ± 4 -8.9
2.2.56.01. Beta-2-glycoprotein 1 3op8 Homo sapiens Secreted 1 0 4.2 ± 1.8 47 ± 10 -6.1
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 3 4axc Arabidopsis thaliana Eukaryo. plasma 1 0 3.2 ± 2.3 68 ± 15 -4.5
2.2.12.04. ADP-ribosylation factor-binding protein GGA1 1om9 Homo sapiens Golgi 2 0 6.1 ± 1.0 76 ± 21 -5.1
2.2.34.05. Tachystatin-A2 1cix Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 3.9 ± 2.9 65 ± 14 -4.7
1.2.01.01. Focal adhesion kinase 1 2j0k Gallus gallus Eukaryo. plasma 1 0 5.0 ± 2.1 36 ± 2 -4.1
1.2.32.01. Cytochrome P450 2B6, conformation 4 4zv8 Homo sapiens Endoplasm. reticulum 1 0 4.5 ± 1.7 57 ± 11 -11.2
3.4.02.02. Mersacidin, structure in DPC micelles 1mqy Bacillus sp. Secreted 1 0 5.3 ± 0.9 90 ± 12 -6.1
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3b 5kar Mus musculus Secreted 1 0 0.8 ± 1.3 51 ± 4 -3.9
2.3.16.03. Transducin 1got Bos taurus Eukaryo. plasma 3 0 4.9 ± 1.2 61 ± 8 -7.0
1.2.32.01. Cholesterol side-chain cleavage enzyme (P450 11A1), complex with adrenodoxin 3n9y Homo sapiens Mitochon. inner 1 0 4.1 ± 0.6 49 ± 5 -6.2
3.1.28.04. Temporin-A 2maa Rana temporaria Secreted 1 0 7.2 ± 0.5 66 ± 7 -8.4
1.2.33.02. Protoporphyrinogen oxidase 3nks Homo sapiens Mitochon. inner 1 0 4.8 ± 1.0 59 ± 3 -9.6
2.1.60.02. Lasiocepsin 2mbd Lasioglossum laticeps Secreted 1 0 0.6 ± 1.3 47 ± 15 -2.5
2.4.07.01. PX domain of sorting nexin-17 (SNX17) 3fog Homo sapiens Endosome 1 0 3.4 ± 1.0 69 ± 12 -4.9
3.1.25.01. Latarcin-2a (M-zodatoxin-Lt2a) 2g9p Lachesana tarabaevi (Spider) Secreted 1 0 8.5 ± 1.4 77 ± 9 -6.4
1.2.37.01. ADP-ribosyl cyclase 1 3f6y Homo sapiens Eukaryo. plasma 1 0 2.5 ± 2.4 51 ± 9 -6.3
2.4.04.01. Sphingomyelinase C 2ddt Bacillus cereus Secreted 1 0 4.1 ± 1.1 59 ± 8 -7.6
3.2.01.07. Protegrin-5 2nc7 Sus scrofa Secreted 1 0 2.3 ± 1.2 87 ± 6 -2.4
1.1.04.01. Respiratory supercomplex I1III2IV1 5gup Sus scrofa Mitochon. inner 67 0 25.8 ± 1.8 9 ± 0 -304.0
2.1.01.01. Snake phospholipase A2, group II 1pp2 Crotalus atrox Secreted 1 0 3.7 ± 1.3 80 ± 7 -12.9
2.4.42.01. Bactericidal permeability-increasing protein 1bp1 Homo sapiens Secreted 1 0 1.5 ± 2.4 51 ± 17 -4.3
3.1.07.02. Juxtamembrane peptide (651-677) of protein gp160 2me2 Human immunodeficiency virus type 1 Endosome 1 0 7.0 ± 1.1 82 ± 7 -13.1
3.1.30.01. Lactoferrin-based peptide, 39-49 2gmc Homo sapiens Secreted 1 0 3.9 ± 1.7 79 ± 13 -4.6
2.2.34.02. Jingzhaotoxin-11 2a2v Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.0 ± 1.8 74 ± 19 -4.6
3.1.29.02. Indolicidin, with P->A substitution 1hr1 Designed proteins Undefined 1 0 5.4 ± 4.0 84 ± 9 -8.3
2.2.07.01. Acidic stress response factor 3hpe Helicobacter pylori Bact. Gram-neg inner 1 0 3.0 ± 0.7 34 ± 8 -6.1
2.3.04.01. Corticosteroid 11-beta-dehydrogenase, isozyme 1 1xu7 Homo sapiens Endoplasm. reticulum 2 0 7.9 ± 0.2 89 ± 1 -20.2
2.2.06.01. Complement component C8 gamma chain 1lf7 Homo sapiens Secreted 1 0 1.9 ± 2.2 43 ± 12 -2.6
3.4.12.02. Thiostrepton 1e9w Streptomyces azureus Secreted 1 0 7.3 ± 1.5 86 ± 15 -4.9
2.4.06.05. Thermoacidophile-specific fatty acid carrier 3w9k Sulfolobus tokodaii Archaebac. 1 0 2.7 ± 1.4 47 ± 4 -7.1
2.3.12.01. Myotubularin-related protein 1 5c16 Homo sapiens Eukaryo. plasma 1 0 4.8 ± 0.7 70 ± 16 -5.3
2.2.34.08. Agouti-signaling protein 1y7j Homo sapiens Secreted 1 0 3.8 ± 1.6 62 ± 7 -6.9
2.3.06.05. Carboxylesterase 2h1i Bacillus cereus Bact. Gram-pos plas. 1 0 2.3 ± 1.8 32 ± 31 -3.6
2.1.01.01. Snake phospholipase A2, ammodytoxin A, group II 3g8g Vipera ammodytes ammodytes Secreted 1 0 4.1 ± 0.9 80 ± 6 -11.0
2.3.24.02. Hydrolase 3n1u Legionella pneumophila Undefined 4 0 5.6 ± 0.6 90 ± 1 -10.8
1.2.32.01. Cytochrome P450 3A4, conformation 2 3nxu Homo sapiens Endoplasm. reticulum 1 0 9.3 ± 1.0 52 ± 12 -17.5
2.2.34.02. ACTX-HI:OB4219 1kqi Hadronyche infensa Secreted 1 0 5.2 ± 1.2 72 ± 15 -8.2
3.1.28.02. Neuromedin-B 1c98 Homo sapiens Secreted 1 0 4.3 ± 1.8 77 ± 11 -3.8
2.2.14.01. Retinoschisin 3jd6 Homo sapiens Eukaryo. plasma 8 0 1.4 ± 0.1 90 ± 0 -19.5
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 1 1ok8 Dengue virus Viral 3 0 5.2 ± 0.9 0 ± 6 -9.5
3.2.02.02. Chi-conotoxin MrIB 1ieo Conus marmoreus Secreted 1 0 2.2 ± 1.1 45 ± 12 -1.9
3.1.18.01. Delta-hemolysin 1dtc Staphylococcus aureus Secreted 1 0 3.2 ± 2.2 87 ± 19 -8.5
2.4.06.04. STAR-related bacterial protein 3ggn Deinococcus radiodurans Undefined 1 0 5.2 ± 1.6 53 ± 8 -4.1
1.2.42.01. Glideosome-associated protein 50 3tgh Plasmodium falciparum Endoplasm. reticulum 1 0 4.2 ± 3.4 69 ± 3 -4.3
2.2.39.01. Toxin B 1txa Ophiophagus hannah Secreted 1 0 2.6 ± 1.5 51 ± 16 -5.6
2.2.32.01. ADP-ribosylating toxin CARDS, full-length 4tlw Mycoplasma pneumoniae Secreted 1 0 1.5 ± 1.4 47 ± 2 -4.8
2.2.05.01. Azurin I 1rkr Alcaligenes xylosoxidans Bact. Gram-neg inner 1 0 1.0 ± 1.0 43 ± 7 -4.3
3.2.06.01. Growth-blocking peptide, long form 2eqt Pseudaletia separata (Oriental armyworm) Secreted 1 0 4.1 ± 1.4 59 ± 8 -5.7
2.2.20.01. Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 4a6f Saccharomyces cerevisiae Eukaryo. plasma 1 0 1.9 ± 1.6 62 ± 4 -6.1
2.2.12.01. Lymphocyte antigen 96, structure 1 2e56 Homo sapiens Secreted 1 0 3.6 ± 0.7 68 ± 4 -6.7
3.2.01.09. Chignolin 5awl Designed proteins Undefined 1 0 2.6 ± 2.1 77 ± 28 -2.8
1.2.32.01. Cytochrome P450 2B6, conformation 3 4i91 Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 2.9 59 ± 11 -11.3
2.3.06.07. Lipase 1qge Pseudomonas glumae Secreted 1 0 3.7 ± 0.9 24 ± 3 -7.7
2.3.19.01. Toxin A 4r04 Clostridium difficile Secreted 1 0 3.2 ± 2.4 74 ± 2 -6.7
2.2.06.02. Cellular retinol-binding protein III 1ggl Homo sapiens Eukaryo. plasma 1 0 3.3 ± 1.9 53 ± 16 -4.9
1.2.43.01. Envelope glycoprotein 3p54 Japanese encephalitis virus Viral 1 0 6.1 ± 2.2 18 ± 6 -6.5
2.2.45.02. Pectate lyase A 1pe9 Erwinia chrysanthemi Secreted 1 0 2.7 ± 0.4 81 ± 3 -6.4
2.2.45.01. Pertactin, complex with phage tail protein 2iou Bordetella bronchiseptica Bact. Gram-neg outer 4 0 3.9 ± 1.2 82 ± 2 -8.2
2.4.16.01. Alpha-like toxin CsEv5 1i6f Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.4 ± 1.3 59 ± 4 -5.8
3.1.04.02. Major prion protein, peptide 110-136 2lbg Homo sapiens Eukaryo. plasma 1 0 5.0 ± 7.0 86 ± 1 -9.3
3.1.19.01. Cephaibol B 1ob6 Acremonium tubakii Secreted 1 0 15.0 ± 5.0 42 ± 17 -15.3
2.1.02.01. Arachidonate 15-lipoxygenase 5ir4 Pseudomonas aeruginosa Secreted 1 0 4.9 ± 1.8 71 ± 2 -11.8
2.2.27.01. Kinase supressor of Ras, Ksr 1kbf Mus musculus Eukaryo. plasma 1 0 1.8 ± 1.0 63 ± 11 -5.4
2.1.08.01. Mitochondrial cytochrome c 1hrc Equus caballus Mitochon. inner 1 0 2.1 ± 1.0 80 ± 16 -2.6
2.2.01.01. F18 fimbrial adhesin AC, FedF 4b4q Escherichia coli Secreted 1 0 1.8 ± 2.6 81 ± 20 -3.4
2.2.06.02. Intestinal fatty acid binding protein, structure 3 2mji Homo sapiens Eukaryo. plasma 1 0 3.3 ± 1.0 57 ± 14 -4.1
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 3 4jch Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.2 88 ± 1 -6.0
3.1.29.01. Cathelicidin-3, peptide 121-151 2hfr Gallus gallus Secreted 1 0 3.1 ± 4.2 86 ± 1 -8.0
2.2.20.01. Ras-specific guanine nucleotide-releasing factor 2dtc Mus musculus Eukaryo. plasma 1 0 2.7 ± 0.4 64 ± 9 -6.3
2.1.01.01. Snake phospholipase A2 isoform 5, group I 1y75 Naja sagittifera Secreted 1 0 4.4 ± 0.7 81 ± 10 -5.7
2.4.34.01. Type-3 ice-structuring protein HPLC 12 4ny6 Zoarces americanus Secreted 1 0 3.3 ± 0.8 58 ± 9 -5.8
2.2.20.01. Oxysterol binding protein-related protein 11 2d9x Homo sapiens Eukaryo. plasma 1 0 1.4 ± 1.7 55 ± 18 -3.1
3.4.04.01. Daptomycin, Ca-free 1xt7 Streptomyces roseosporus Secreted 1 0 9.3 ± 3.9 10 ± 45 -6.4
3.1.21.10. Pilosulin-1 5x3l Myrmecia pilosula Secreted 1 0 7.6 ± 3.2 82 ± 7 -8.5
3.1.03.03. Membrane-bound helix of phosphotransferase IIA component 1o53 Escherichia coli Bact. Gram-neg inner 1 0 3.3 ± 1.3 86 ± 15 -7.8
2.4.06.02. Phosphatidylinositol transfer protein beta isoform 2a1l Rattus norvegicus Eukaryo. plasma 1 0 4.7 ± 1.7 36 ± 17 -4.3
3.1.28.06. Magainin 2 2mag Xenopus laevis Secreted 1 0 10.1 ± 0.9 81 ± 14 -13.7
2.4.16.04. Flower-specific defensin, monomer 4ab0 Nicotiana alata (Winged tobacco) Secreted 1 0 3.5 ± 1.2 55 ± 13 -4.3
3.1.07.04. Juxtamembrane peptide of hepatis C virus E1 glycoprotein (314-342) 2knu Hepatitis C virus Endosome 1 0 5.3 ± 0.9 82 ± 6 -5.9
3.1.10.01. Competence-stimulating peptide type 1 2a1c Streptococcus pneumoniae Secreted 1 0 4.8 ± 0.9 85 ± 20 -7.7
1.2.32.01. Cytochrome P450 120a1 2ve4 Synechocystis sp. Thylakoid 1 0 6.3 ± 0.9 47 ± 8 -8.6
2.3.06.06. Lipase LipA 2qua Serratia marcescens Secreted 1 0 8.9 ± 0.2 59 ± 0 -37.5
2.2.12.01. Ganglioside GM2 activator, apo-protein 2ag4 Homo sapiens Lysosome 1 0 3.1 ± 1.3 58 ± 12 -5.4
2.3.04.01. Sorbitol dehydrogenase 1k2w Rhodobacter sphaeroides Bact. Gram-neg inner 2 0 2.2 ± 0.3 89 ± 1 -4.4
2.3.14.01. Neurofibromin 2d4q Homo sapiens Eukaryo. plasma 1 0 1.6 ± 2.0 34 ± 19 -3.3
2.1.01.01. Snake phospholipase A2, group I, KPA2 1g2x Bungarus caeruleus Secreted 1 0 3.8 ± 1.5 84 ± 10 -5.4
2.2.34.02. Mu-cyrtautoxin-As1a 2m36 Apomastus schlingeri Secreted 1 0 1.7 ± 1.0 49 ± 35 -3.2
2.2.26.01. FYVE domain of Vps27 protein 1vfy Saccharomyces cerevisiae Vacuole 1 0 3.7 ± 1.8 24 ± 19 -4.2
2.2.34.02. Omega-theraphotoxin-Gr1a 1koz Grammostola rosea (Chilean rose tarantula) Secreted 1 0 3.6 ± 0.8 68 ± 6 -6.5
2.2.07.01. Lipocalin BcnA 5ixh Burkholderia cepacia Bact. Gram-neg inner 1 0 1.4 ± 2.6 28 ± 29 -1.7
2.2.04.01. Retinoid isomerohydrolase, conformation 2 4f2z Bos taurus Eukaryo. plasma 1 0 3.7 ± 0.9 56 ± 2 -9.2
1.2.29.01. Septation ring formation regulator EzrA 4uy3 Staphylococcus aureus Bact. Gram-pos plas. 1 0 1.2 ± 2.8 44 ± 4 -3.0
3.1.29.03. Tritrpticin 1d6x Sus scrofa Secreted 1 0 9.4 ± 2.6 81 ± 38 -8.1
3.1.05.04. Distinctin 1xkm Designed proteins Undefined 2 0 3.9 ± 0.4 87 ± 2 -4.6
2.1.18.01. Annexin IV 2zoc Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.1 82 ± 7 -7.6
3.1.07.05. Nonstructural protein 5a, segment 1973-2003 1r7g Human hepatitis C virus Endoplasm. reticulum 1 0 5.3 ± 0.9 90 ± 5 -15.1
2.2.06.01. Retinol binding protein 1aqb Sus scrofa Secreted 1 0 4.1 ± 1.1 75 ± 14 -4.4
2.1.25.03. Enterocin 7B 2m60 Enterococcus faecalis Secreted 1 0 3.2 ± 1.6 53 ± 15 -3.8
2.3.08.02. Cytosolic phospholipase A2 delta, structure 1 5ixc Homo sapiens Vesicle 1 0 5.5 ± 2.0 85 ± 31 -4.4
2.2.34.01. Conotoxin Gm9 1ixt Conus gloriamaris (Glory-of-the-Seas cone) Secreted 1 0 1.7 ± 1.7 85 ± 17 -3.0
2.4.20.02. Arylamine N-acetyltransferase 1w5r Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 2.6 ± 0.5 82 ± 6 -6.2
2.3.07.01. Endoglucanase 1vho Thermotoga maritima Undefined 1 0 5.4 ± 0.2 89 ± 1 -7.0
2.3.09.01. Cytidylyltransferase 3hl4 Rattus norvegicus Eukaryo. plasma 2 0 2.7 ± 4.0 74 ± 8 -3.2
2.4.16.01. Beta-mammal toxin Cn2 2yc1 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.8 ± 1.1 68 ± 9 -3.8
1.2.50.01. Fragaceatoxin C, complex with lipids 4tsq Actinia fragacea (Strawberry anemone) Secreted 1 0 2.2 ± 0.9 38 ± 3 -15.5
2.1.18.01. Annexin GH1 1n00 Gossypium hirsutum Eukaryo. plasma 1 0 1.5 ± 2.0 70 ± 17 -3.7
1.2.60.01. Dysferlin, dysferlin domain 4cah Homo sapiens Eukaryo. plasma 1 0 5.5 ± 1.4 23 ± 5 -6.0
3.1.20.01. Alpha-conotoxin GID 1mtq