PDB ID or protein name

All proteins in OPM (3566 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
1.2.32.01. Cytochrome P450 1A1 4i8v Homo sapiens Endoplasm. reticulum 1 0 7.1 ± 1.0 64 ± 3 -15.1
2.4.16.02. Sapecin 1l4v Sarcophaga peregrina Secreted 1 0 5.4 ± 1.5 84 ± 18 -5.1
3.1.29.01. Fowlicidin-2 2gdl Gallus gallus Secreted 1 0 3.1 ± 0.5 85 ± 4 -8.9
2.3.06.01. Acetylcholinesterase 1n5m Mus musculus Eukaryo. plasma 1 0 3.7 ± 1.3 28 ± 6 -6.1
3.1.11.01. Neuropeptide F 1k8v Moniezia expansa (Sheep tapeworm) Secreted 1 0 2.9 ± 1.1 68 ± 9 -7.0
2.1.01.01. Phospholipase A2, beta bungarotoxin A1 chain, complex with bungarotoxin 1bun Bungarus multicinctus Secreted 2 0 1.7 ± 0.9 79 ± 3 -3.8
2.1.46.01. Protein yciE 3ogh Escherichia coli Undefined 2 0 4.0 ± 1.0 88 ± 4 -9.7
1.2.03.03. Myelin protein P0 3oai Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.2 72 ± 6 -5.8
2.3.06.03. Gastric lipase, closed state 1hlg Homo sapiens Secreted 1 0 3.2 ± 1.4 6 ± 12 -5.6
2.3.06.01. Carboxylic ester hydrolase, closed state 4be4 Ophiostoma piceae Secreted 1 0 6.4 ± 2.3 61 ± 4 -5.7
3.1.03.03. Membrane-bound helix of phosphotransferase IIA component 1o53 Escherichia coli Bact. Gram-neg inner 1 0 3.3 ± 1.3 86 ± 15 -7.8
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1uw5 Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.5 18 ± 16 -5.4
1.2.43.01. Envelope glycoprotein, West Nile virus, structure 2 2i69 West Nile virus Viral 1 0 6.7 ± 2.8 5 ± 12 -5.0
3.2.08.01. Peptide 35-42, alternate polymorph I 2y3k Homo sapiens Secreted 2 0 3.4 ± 1.4 89 ± 4 -7.2
2.4.11.01. Beta-hordothionin 1wuw Hordeum vulgare Secreted 1 0 3.6 ± 1.1 55 ± 15 -5.4
2.3.06.18. Protein lpg2422 4m0m Legionella pneumophila Undefined 1 0 4.6 ± 2.9 76 ± 6 -6.9
2.1.51.01. Protein farnesyltransferase/geranylgeranyltransferase 1jcr Rattus norvegicus Eukaryo. plasma 2 0 3.2 ± 2.3 56 ± 5 -5.6
3.1.17.01. Antimicrobial peptide HP 1p0l Helicobacter pylori Secreted 1 0 5.3 ± 0.6 79 ± 9 -10.5
3.1.11.02. Exendin-4-conotoxin chimera 2naw Designed proteins Secreted 1 0 4.3 ± 1.4 69 ± 8 -2.7
2.3.04.01. Sorbitol dehydrogenase 1k2w Rhodobacter sphaeroides Bact. Gram-neg inner 2 0 2.2 ± 0.3 89 ± 1 -4.4
2.4.06.02. Phosphatidylinositol transfer protein beta isoform 2a1l Rattus norvegicus Eukaryo. plasma 1 0 4.7 ± 1.7 36 ± 17 -4.3
1.2.32.01. Cytochrome P450 24a1 (1,25-dihydroxyvitamin D(3) 24-hydroxylase) 3k9v Rattus norvegicus Mitochon. inner 1 0 6.6 ± 1.0 49 ± 6 -9.6
2.3.30.01. Aspartate carbamoyltransferase 5ilq Plasmodium falciparum Chloroplast outer 3 0 3.0 ± 0.4 88 ± 1 -7.2
2.1.14.02. SusD superfamily protein 3myv Bacteroides vulgatus Secreted 1 0 4.0 ± 1.0 64 ± 2 -6.0
2.1.41.01. Phosphatidylinositol 4-kinase type 2-alpha, structure 2 4pla Homo sapiens Golgi 1 0 1.0 ± 1.7 49 ± 3 -2.8
2.2.41.01. Neutrophil defensin 1 2pm1 Homo sapiens Secreted 1 0 3.6 ± 1.3 85 ± 6 -3.8
1.2.32.01. Cytochrome P450 3A4, conformation 3 5te8 Homo sapiens Endoplasm. reticulum 1 0 4.4 ± 1.6 62 ± 5 -13.6
3.4.02.02. Mersacidin, structure in methanol solution 1mqx Bacillus sp. Secreted 1 0 1.9 ± 1.3 87 ± 15 -2.9
1.2.39.02. Matrilysin, structure 1 2mze Homo sapiens Secreted 1 0 3.3 ± 0.9 68 ± 2 -8.0
2.3.14.01. Neurofibromin 2d4q Homo sapiens Eukaryo. plasma 1 0 1.6 ± 2.0 34 ± 19 -3.3
3.1.19.01. Paracelsin X 4by8 Trichoderma reesei Secreted 1 0 14.6 ± 5.1 60 ± 4 -14.6
2.4.07.01. PX domain of serine/threonine-protein kinase Sgk3 1xte Homo sapiens Endosome 1 0 1.2 ± 1.4 77 ± 11 -2.9
2.4.16.02. Phormicin 1ica Protophormia terraenovae (Northern blowfly) Secreted 1 0 3.7 ± 2.3 90 ± 23 -5.0
2.2.04.01. Retinoid isomerohydrolase, conformation 2 4f2z Bos taurus Eukaryo. plasma 1 0 3.7 ± 0.9 56 ± 2 -9.2
1.2.32.01. Plant cytochrome P450 74A (allene oxide synthase) 3dsk Arabidopsis thaliana Thylakoid 1 0 5.7 ± 0.5 67 ± 3 -20.0
2.4.11.01. Viscotoxin A3 1okh Viscum album Secreted 1 0 4.6 ± 1.3 32 ± 19 -4.9
3.1.20.01. O2-contryphan-Vc2 5l34 Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.4 85 ± 8 -4.2
2.1.18.01. Annexin IV 2zoc Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.1 82 ± 7 -7.6
2.1.23.01. Ectatomin 1eci Ectatomma tuberculatum Secreted 2 0 5.3 ± 1.8 58 ± 15 -5.2
3.1.07.02. Juxtamembrane peptide (659-685) of protein gp160 2fx7 Human immunodeficiency virus type 1 Endosome 1 0 6.2 ± 1.0 73 ± 7 -8.0
2.1.19.01. Antifungal peptide 2l2r Echinochloa crus-galli Secreted 1 0 3.4 ± 1.5 50 ± 8 -3.8
2.4.01.01. Cholesterol oxidase 1coy Brevibacterium sterolicum Bact. Gram-pos plas. 1 0 4.4 ± 1.1 43 ± 10 -6.8
2.1.24.01. Pulmonary surfactant-associated protein B fragments 2dwf Homo sapiens Secreted 1 0 5.6 ± 1.3 77 ± 4 -9.5
2.3.06.19. Thermostable lipase 5h6b Streptomyces sp. Secreted 1 0 4.4 ± 0.8 58 ± 41 -8.2
2.3.09.01. Cytidylyltransferase 3hl4 Rattus norvegicus Eukaryo. plasma 2 0 2.7 ± 4.0 74 ± 8 -3.2
2.1.01.01. Phospholipase A2, group IIA 1n28 Homo sapiens Secreted 1 0 3.6 ± 0.6 88 ± 4 -7.0
3.4.01.01. Contryphan-In 2m6d Conus inscriptus Secreted 1 0 8.2 ± 1.0 57 ± 15 -5.8
2.3.16.01. Shikimate kinase 1via Campylobacter jejuni Bact. Gram-neg inner 2 0 3.9 ± 1.4 89 ± 11 -5.0
2.1.18.01. Annexin GH1 1n00 Gossypium hirsutum Eukaryo. plasma 1 0 1.5 ± 2.0 70 ± 17 -3.7
2.1.33.01. DrrA protein, PtdIns(4) binding domain, complex with PtdIns(4) 4mxp Legionella pneumophila Vacuole 1 0 2.8 ± 2.6 59 ± 12 -4.5
3.1.11.02. Pituitary adenylate cyclase activating polypeptide (PACAP)-38 2d2p Homo sapiens Secreted 1 0 3.9 ± 4.0 90 ± 0 -6.8
2.3.06.12. Esterase LipW 3qh4 Mycobacterium marinum Bact. Gram-pos plas. 1 0 2.4 ± 1.2 76 ± 32 -5.0
3.1.26.01. Piscidin 1 2ojm Morone saxatilis Secreted 1 0 10.6 ± 1.0 82 ± 13 -16.3
2.2.27.01. C1 domain of protein kinase C delta 2yuu Homo sapiens Nuclear outer 1 0 4.0 ± 0.9 77 ± 20 -6.5
2.2.20.01. Pleckstrin homology domain-containing family A member 5 (PLEKHA5) 2dkp Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.9 64 ± 6 -3.9
1.2.32.01. Cytochrome P450 2A13 2p85 Homo sapiens Endoplasm. reticulum 1 0 4.9 ± 0.4 47 ± 2 -10.0
2.2.34.11. Kalata B1, segment 93-120 1nb1 Oldenlandia affinis Secreted 1 0 5.3 ± 1.4 81 ± 18 -5.5
2.1.60.03. Pseudecin, conformation 2 2epf Pseudechis porphyriacus Secreted 1 0 5.4 ± 1.1 86 ± 1 -4.6
2.2.20.01. Dual adaptor of phosphotyrosine and 3-phosphoinositides 1fao Homo sapiens Eukaryo. plasma 1 0 2.4 ± 2.0 59 ± 19 -3.9
2.2.34.02. Delta-amaurobitoxin-Pl1b 1v91 Pireneitega luctuosa (Tangled nest spider) Secreted 1 0 2.4 ± 0.9 35 ± 4 -5.7
2.3.06.09. Cutinase 1 3dcn Colletotrichum gloeosporioides Secreted 1 0 5.7 ± 1.2 44 ± 8 -10.1
2.3.24.02. Predicted hydrolase 3mpo Lactobacillus brevis Undefined 1 0 3.6 ± 0.0 83 ± 7 -5.7
2.2.34.11. Vodo peptide N 2aks Viola odorata Secreted 1 0 4.0 ± 1.4 89 ± 22 -6.7
2.2.48.01. Hypothetical molybdopterin biosynthesis MoeA protein 1uz5 Pyrococcus horikoshii Undefined 1 0 4.7 ± 1.7 79 ± 2 -5.0
2.3.16.06. ADP-ribosylation factor-like protein 1 2x77 Leishmania major Eukaryo. plasma 1 0 1.6 ± 1.4 80 ± 5 -3.6
2.2.39.01. Cardiotoxin III (cytotoxin 3) 1h0j Naja atra Secreted 1 0 7.1 ± 0.9 59 ± 7 -11.3
3.2.01.07. Protegrin-3, dimer 2mz6 Sus scrofa Secreted 2 0 0.4 ± 2.1 89 ± 2 -2.3
2.2.11.01. Phosphatidylinositide 3-kinase C2 alpha 2b3r Mus musculus Eukaryo. plasma 2 0 1.4 ± 1.5 88 ± 16 -4.4
3.2.06.01. Growth-blocking peptide 2djc Spodoptera litura Secreted 1 0 2.9 ± 2.0 19 ± 14 -3.1
3.1.02.01. C-terminal helix of MCP-1 receptor 2mlo Homo sapiens Eukaryo. plasma 1 0 6.0 ± 1.6 86 ± 8 -10.1
2.2.12.01. Lymphocyte antigen 86 3mtx Gallus gallus Secreted 1 0 2.3 ± 1.6 69 ± 11 -2.4
3.1.04.07. Peptide (2-25) of antifreeze protein Afp1 2lq0 Glaciozyma antarctica Undefined 1 0 4.0 ± 3.8 85 ± 2 -9.5
2.2.03.01. Beta-secretase 1 2wf1 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 61 ± 6 -4.9
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 6 4coh Trypanosoma cruzi Endoplasm. reticulum 1 0 6.3 ± 1.3 56 ± 6 -7.3
2.3.06.19. Lipase A 1isp Bacillus subtilis Secreted 1 0 1.9 ± 0.8 59 ± 12 -5.2
2.3.01.06. Glycosyl hydrolase PslG 5bxa Pseudomonas aeruginosa Secreted 1 0 6.0 ± 1.2 72 ± 9 -6.9
1.2.43.06. Outer capsid protein VP4, trimer 2b4i Rotavirus A Viral 3 0 2.9 ± 0.3 2 ± 0 -11.7
2.1.52.01. Pheromone binding protein 1ow4 Rhyparobia maderae (Madeira cockroach) Secreted 1 0 4.4 ± 0.8 30 ± 16 -4.4
2.4.06.01. STAR-related lipid transfer protein 11, apoprotein (open state) 2e3m Homo sapiens Golgi 1 0 3.4 ± 1.1 44 ± 12 -6.1
2.4.16.01. Alpha-mammal toxin BmK-M8 1snb Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.4 ± 2.4 79 ± 22 -2.3
3.4.04.03. Tridecaptin A1 2n5y Designed proteins Undefined 1 0 2.1 ± 1.0 89 ± 7 -3.9
2.3.16.07. GTP-binding protein Rheb 1xtq Homo sapiens Eukaryo. plasma 1 0 2.6 ± 0.6 76 ± 20 -5.1
1.2.32.01. Cytochrome P450 2B6, conformation 4 4zv8 Homo sapiens Endoplasm. reticulum 1 0 4.5 ± 1.7 57 ± 11 -11.2
3.1.19.01. Cephaibol A 1ob4 Acremonium tubakii Secreted 1 0 14.1 ± 2.5 58 ± 18 -14.7
2.2.34.06. Peptide jS1 2n5q Jasminum sambac Secreted 1 0 3.8 ± 1.2 71 ± 15 -6.1
2.3.32.01. UDP-N-acetylmuramate--L-alanine ligase 1p31 Haemophilus influenzae Bact. Gram-neg inner 1 0 4.4 ± 1.8 29 ± 14 -4.6
2.3.11.01. Ferrochelatase, mitochondrial 1lbq Saccharomyces cerevisiae Mitochon. inner 2 0 5.3 ± 0.5 90 ± 3 -6.9
1.2.50.01. Fragaceatoxin C, trimer 3zwj Actinia fragacea (Strawberry anemone) Secreted 3 0 2.4 ± 0.2 89 ± 4 -8.4
1.2.51.01. Bis(5-adenosyl)-triphosphatase ENPP4 4lqy Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 81 ± 12 -5.5
2.1.14.01. Peroxisome targeting signal 1 receptor PEX5 1hxi Trypanosoma brucei Peroxisome 1 0 3.7 ± 1.0 71 ± 5 -8.1
3.2.01.07. Protegrin-1 1pg1 Sus scrofa Secreted 1 0 2.2 ± 0.4 72 ± 4 -4.2
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1aod Listeria monocytogenes Secreted 1 0 7.4 ± 1.0 79 ± 10 -9.2
2.2.39.02. Mambalgin-2 2mfa Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 2.7 ± 2.5 76 ± 5 -6.4
2.3.06.02. Antigen 85c, conformation 3 1dqy Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 5.1 ± 1.2 17 ± 3 -6.1
3.1.28.06. Magainin 2, Ala-analogue 4mgp Designed proteins Secreted 1 0 10.0 ± 4.1 79 ± 2 -15.1
3.1.02.01. Fourth intracellular loop of CB1 cannabinoid receptor 2mz2 Designed proteins Eukaryo. plasma 1 0 6.3 ± 1.2 80 ± 6 -7.4
3.1.07.02. Juxtamembrane peptide (665-683) of protein gp41 1jau Human immunodeficiency virus type 1 Endosome 1 0 4.0 ± 4.2 86 ± 2 -8.0
3.1.28.04. Phylloseptin-1 2jq0 Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 9.5 ± 1.4 76 ± 7 -13.5
2.4.14.01. 1-acyl-sn-glycerol-3-phosphate acyltransferase 5kym Thermotoga maritima Bact. Gram-neg inner 1 0 20.2 ± 1.0 28 ± 2 -32.3
2.2.34.06. Tripatide 2mfs Trichocereus pachanoi Thylakoid 1 0 4.1 ± 0.8 81 ± 6 -7.6
2.2.08.01. Osmotin 1pcv Nicotiana tabacum Secreted 1 0 2.4 ± 1.9 82 ± 19 -2.7
3.1.28.09. Pseudin-2, structure 1 2ncy Pseudis paradoxa Secreted 1 0 4.9 ± 3.0 77 ± 5 -5.8
2.2.11.01. Rabphilin-3A, C2B domain 2cm5 Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 2.0 56 ± 14 -4.1
2.2.06.02. Prostaglandin-H2 D-isomerase, ligand-bound 3o22 Homo sapiens Endoplasm. reticulum 1 0 0.7 ± 1.2 78 ± 13 -2.4
2.1.01.01. Snake phospholipase A2, group I, acidic 2 1m8t Ophiophagus hannah Secreted 1 0 4.4 ± 0.8 88 ± 6 -6.6
1.2.55.01. Neutral ceramidase, structure 2 2zxc Pseudomonas aeruginosa Secreted 1 0 4.6 ± 1.7 71 ± 8 -7.6
2.1.08.01. Cytochrome c552 1a8c Nitrosomonas europaea Bact. Gram-neg inner 1 0 2.7 ± 1.0 80 ± 11 -4.7
2.2.11.01. Synaptotagmin-1, C2A domain (Calcium bound) 1byn Rattus norvegicus Eukaryo. plasma 1 0 3.8 ± 1.6 32 ± 19 -4.7
3.4.02.06. Epilancin 15X 1w9n Staphylococcus epidermidis Secreted 1 0 2.9 ± 1.0 72 ± 7 -5.0
1.2.38.01. Penicillin-binding protein 2 2olv Staphylococcus aureus Bact. Gram-pos plas. 1 0 3.7 ± 2.0 58 ± 8 -7.3
3.2.02.02. T-2-conotoxin MrIA 2ew4 Conus marmoreus Secreted 1 0 2.5 ± 1.5 81 ± 19 -3.0
2.2.12.01. Ganglioside GM2 activator, apo-protein 2ag4 Homo sapiens Lysosome 1 0 3.1 ± 1.3 58 ± 12 -5.4
2.3.06.13. Protein Ndr1 2xmr Homo sapiens Eukaryo. plasma 1 0 8.2 ± 2.6 50 ± 10 -8.8
1.2.32.01. Cytochrome P450 2R1 3czh Homo sapiens Endoplasm. reticulum 1 0 8.3 ± 1.5 48 ± 13 -13.2
2.2.06.01. Epididymal-specific lipocalin-5 1epb Rattus norvegicus Secreted 1 0 6.4 ± 1.1 74 ± 4 -3.8
3.4.12.01. Actinomycin X2 1qfi Streptomyces antibioticus Secreted 1 0 15.2 ± 2.3 35 ± 34 -14.1
3.1.02.11. Methyl-accepting chemotaxis protein II 2l9g Escherichia coli Bact. Gram-neg inner 1 0 8.1 ± 4.2 75 ± 0 -11.7
2.2.12.02. Rho GDP-dissociation inhibitor 2, complex with G-protein RAC2 1ds6 Homo sapiens Eukaryo. plasma 2 0 2.8 ± 1.0 82 ± 6 -5.5
2.2.18.01. Subunit mu of AP-2 clatrin adaptor complex, open conformation 2xa7 Rattus norvegicus Vesicle 4 0 3.1 ± 2.2 84 ± 14 -5.9
2.4.17.01. Vitellogenin 1lsh Ichthyomyzon unicuspus (Silver lamprey) Secreted 1 0 3.4 ± 1.3 81 ± 0 -4.6
2.2.27.01. Ras association domain-containing protein 5, C1 domain 1rfh Mus musculus Eukaryo. plasma 1 0 1.4 ± 0.9 16 ± 6 -3.7
2.1.01.01. Snake phospholipase A2, acidic, group II 1ijl Agkistrodon acutus Secreted 1 0 4.2 ± 1.2 83 ± 12 -7.5
3.1.03.03. Anticancer peptide designed based on the helix of phosphotransferase IIA 1vm2 Designed proteins Undefined 1 0 7.0 ± 1.8 78 ± 15 -12.0
1.2.04.01. Integrin beta-3, 742-788, in micelles 1s4x Homo sapiens Eukaryo. plasma 1 0 6.9 ± 1.0 18 ± 10 -5.8
2.3.06.15. Polyneuridine-aldehyde esterase 2wfm Rauvolfia serpentina (Serpentwood) Endoplasm. reticulum 1 0 2.5 ± 1.7 88 ± 3 -4.6
2.2.34.02. omega-Agatoxin 1agg Agelenopsis aperta Secreted 1 0 2.5 ± 1.4 57 ± 17 -5.0
3.1.11.01. Neuropeptide Y analogue 1icy Sus scrofa Secreted 1 0 6.4 ± 0.5 69 ± 6 -8.1
2.2.06.02. Intestinal fatty acid binding protein, structure 1 1kzw Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.3 61 ± 12 -4.1
3.1.20.01. Alpha-conotoxin EIVA 1pqr Conus ermineus Secreted 1 0 2.5 ± 1.3 14 ± 14 -3.4
2.3.10.02. Beta-1,2-glucuronosyltrnansferase GumK 2q6v Xanthomonas campestris Bact. Gram-neg inner 1 0 5.2 ± 1.0 61 ± 8 -9.5
2.2.06.02. Retinoid-binding protein 7 1lpj Homo sapiens Eukaryo. plasma 1 0 2.6 ± 1.1 44 ± 13 -6.0
1.2.39.01. Leucyl-cystinyl aminopeptidase, structure 2 5mj6 Homo sapiens Eukaryo. plasma 1 0 1.8 ± 1.4 76 ± 4 -3.5
3.1.07.03. Hemagglutinin, peptide 330-349, F9A 2jrd Influenza virus Viral 1 0 8.1 ± 4.0 71 ± 5 -6.8
3.1.20.01. Alpha-conotoxin GIA 1not Conus geographus (Geography cone) Secreted 1 0 1.6 ± 1.5 89 ± 20 -2.3
2.2.07.02. Factor H binding protein 1ys5 Neisseria meningitidis Bact. Gram-neg outer 1 0 3.5 ± 2.6 84 ± 5 -5.6
3.1.12.01. Endothelin-1 3cmh Rattus norvegicus Secreted 1 0 6.3 ± 3.9 72 ± 40 -4.8
2.3.22.02. NrdI protein 2xod Bacillus anthracis Undefined 1 0 4.1 ± 0.4 72 ± 3 -4.8
2.3.10.07. Lipopolysaccharide biosynthesis protein RfaG, 103-131 2n58 Escherichia coli Bact. Gram-neg inner 1 0 4.5 ± 1.1 64 ± 7 -6.3
3.1.04.02. Major prion protein, peptide 173-195 2iv5 Homo sapiens Eukaryo. plasma 1 0 5.3 ± 4.1 83 ± 17 -3.5
1.2.53.01. Squalene synthase, conformation 2 3wcf Homo sapiens Endoplasm. reticulum 1 0 2.8 ± 0.8 87 ± 3 -7.0
2.2.41.02. Sea anemone neurotoxin-1 1shi Stoichactis helianthus Secreted 1 0 8.0 ± 1.0 87 ± 17 -5.9
2.3.06.09. Cutinase 4oyy Humicola insolens (Soft-rot fungus) Secreted 1 0 4.9 ± 1.4 46 ± 6 -10.0
2.2.27.01. RAF-1 proto-oncogene serine/threonine-protein kinase 1faq Homo sapiens Eukaryo. plasma 1 0 4.8 ± 1.1 30 ± 14 -7.3
2.3.01.02. Beta-glucosidase 6 3gnr Oryza sativa (Rice) Secreted 1 0 4.8 ± 0.2 80 ± 1 -12.4
2.2.12.01. Lymphocyte antigen 96, structure 2 4g8a Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.3 67 ± 6 -3.8
2.4.05.02. SDS hydrolase SdsA1 2cfu Pseudomonas aeruginosa Secreted 1 0 6.0 ± 2.5 70 ± 4 -7.0
3.2.05.02. Microcin J25, redesigned, version 2 2mmw Designed proteins Undefined 1 0 2.6 ± 3.5 90 ± 4 -3.7
2.2.20.01. Rho guanine nucleotide exchange factor 9 complex 2dfk Rattus norvegicus Eukaryo. plasma 2 0 2.8 ± 2.7 69 ± 3 -5.0
2.4.11.01. Crambin 1ejg Crambe abyssinica Secreted 1 0 4.0 ± 1.7 79 ± 15 -7.0
2.3.16.06. ADP-ribosylation factor-like protein 2, complex with human PDEdelta 1ksg Mus musculus Eukaryo. plasma 1 0 6.9 ± 1.7 77 ± 15 -5.7
2.3.05.02. Adrenodoxin reductase of mitochondrial p450 systems, complex with adrenodoxin 1e6e Bos taurus Mitochon. inner 2 0 2.3 ± 1.0 11 ± 2 -4.1
1.2.45.02. Small hydrophobic protein, peptide 39-49 2nb8 Human respiratory syncytial virus Viral 1 0 8.5 ± 1.2 57 ± 13 -5.9
2.2.21.05. Kunitz-type proteinase inhibitor BbCI 2gzb Bauhinia bauhinioides Secreted 1 0 7.9 ± 0.3 28 ± 3 -9.3
1.1.59.01. Membrane protease specific for a stomatin homolog, dimer 3viv Pyrococcus horikoshii Archaebac. 2 0 4.5 ± 0.4 88 ± 9 -9.5
2.1.61.01. Muramidase Tse3-Tsi3 complex, conformation 2 4luq Pseudomonas aeruginosa Bact. Gram-neg outer 2 0 2.2 ± 1.4 69 ± 5 -8.2
1.2.17.01. Vesicle-associated membrane protein complex 2nps Mus musculus Golgi 4 0 5.6 ± 2.2 68 ± 4 -5.6
2.1.42.01. PapB 2ip6 Pediococcus pentosaceus Secreted 1 0 0.6 ± 2.6 72 ± 23 -2.2
2.3.25.02. LAE5 5jd3 Uncultured bacterium Undefined 1 0 5.3 ± 5.3 75 ± 3 -7.4
2.2.53.01. Fas apoptotic inhibitory molecule 1 3mx7 Homo sapiens Eukaryo. plasma 1 0 4.2 ± 1.4 16 ± 13 -7.1
3.2.04.01. Cyclic trypsin inhibitor STFI-1, permutant 1o8y Helianthus annuus Secreted 1 0 3.4 ± 1.3 83 ± 18 -6.0
2.2.41.01. Gallinacin-7 5lcs Gallus gallus Secreted 1 0 2.5 ± 1.4 85 ± 5 -5.6
2.2.07.01. Protein yceI 1y0g Escherichia coli Bact. Gram-neg inner 1 0 4.2 ± 1.5 24 ± 16 -2.1
2.3.05.02. Rotenone-insensitive NADH-ubiquinone oxidoreductase, NDI1 4g6h Saccharomyces cerevisiae Mitochon. inner 2 0 4.8 ± 0.0 88 ± 1 -13.9
1.2.22.02. BH3-interacting domain death agonist 2m5i Homo sapiens Mitochon. outer 1 0 6.4 ± 1.5 86 ± 0 -18.8
2.4.16.05. Eurocin 2lt8 Eurotium amstelodami Secreted 1 0 5.3 ± 1.3 84 ± 12 -5.5
2.1.15.02. Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) 1dvp Drosophila melanogaster Endosome 2 0 3.0 ± 0.0 89 ± 0 -6.6
3.1.15.01. Curvacin-A 2a2b Lactobacillus curvatus Secreted 1 0 2.5 ± 1.3 34 ± 18 -6.7
2.3.06.06. Lipase 2 1thg Geotrichum candidum Secreted 1 0 6.4 ± 1.7 23 ± 14 -4.7
2.1.42.01. Lactococcin-A immunity protein 5lfi Lactococcus lactis Secreted 1 0 2.7 ± 1.4 40 ± 9 -4.8
1.1.04.01. Mitochondrial respiratory megacomplex I2III2IV2, lower resolution 5xti Homo sapiens Mitochon. inner 68 0 29.4 ± 0.0 14 ± 0 -212.9
2.2.39.01. Cardiotoxin-A5 1kxi Naja atra Secreted 1 0 6.3 ± 1.1 69 ± 15 -10.5
2.4.16.04. Flower-specific defensin D1, dimer 4cqk Nicotiana alata (Winged tobacco) Secreted 2 0 4.8 ± 2.4 88 ± 6 -7.1
2.3.12.01. Myotubularin-related protein 1 5c16 Homo sapiens Eukaryo. plasma 1 0 4.8 ± 0.7 70 ± 16 -5.3
2.1.21.03. Matrix protein p15 1mn8 Moloney murine leukemia virus Endosome 1 0 1.5 ± 1.8 65 ± 24 -3.5
2.4.16.03. Chlorotoxin 1chl Leiurus quinquestriatus quinquestriatus Secreted 1 0 6.5 ± 1.2 87 ± 14 -4.3
2.3.06.07. Thermostable lipase 2dsn Geobacillus zalihae Secreted 1 0 4.9 ± 0.9 32 ± 3 -7.7
2.2.61.01. Effector protein PevD1 5xmz Verticillium dahliae Secreted 1 0 3.5 ± 0.8 33 ± 2 -5.6
2.3.06.11. Monoglyceride lipase MGLL, open ligand-free conformation 3jw8 Homo sapiens Eukaryo. plasma 1 0 8.1 ± 1.3 11 ± 9 -11.3
1.2.56.01. Fatty aldehyde dehydrogenase 4qgk Homo sapiens Endoplasm. reticulum 2 0 3.5 ± 1.9 83 ± 7 -6.5
2.1.01.01. Snake phospholipase A2, group I, isoform 2 1u4j Bungarus caeruleus Secreted 1 0 2.2 ± 0.6 83 ± 4 -8.5
2.4.16.02. Lucifensin 2lld Lucilia sericata Secreted 1 0 1.1 ± 1.7 11 ± 12 -3.0
2.2.05.01. Azurin iso-2 1cuo Methylomonas sp. Bact. Gram-neg inner 1 0 1.4 ± 1.6 69 ± 15 -4.3
2.1.11.01. Spectrin alpha chain 2spc Drosophila melanogaster Eukaryo. plasma 2 0 4.3 ± 0.8 87 ± 11 -6.2
2.1.33.01. DrrA protein, PtdIns(4) binding domain 3n6o Legionella pneumophila Vacuole 1 0 5.1 ± 1.4 56 ± 10 -4.9
3.2.01.01. Arenicin-2, dimer 2l8x Arenicola marina Secreted 2 0 2.7 ± 1.1 87 ± 4 -4.0
1.2.26.01. Outer membrane lipoprotein Wza, water-soluble part 2w8h Escherichia coli Bact. Gram-neg outer 8 0 1.6 ± 0.2 1 ± 0 -22.1
2.1.03.01. Alpha-toxin (PHLC_CLOP1) , different conformation 1qmd Clostridium perfringens Secreted 1 0 4.8 ± 1.0 80 ± 8 -6.7
1.2.17.02. Vesicle-associated membrane protein 8 (VAMP8)- Syntaxin-17 complex 4wy4 Homo sapiens Lysosome 2 0 6.8 ± 1.3 16 ± 5 -6.0
2.2.06.02. Fatty acid-binding protein 2k62 Gallus gallus Eukaryo. plasma 1 0 0.0 ± 2.9 82 ± 13 -2.0
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 2 3mdm Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 1.3 51 ± 8 -5.9
2.2.06.01. Retinol binding protein 1kt6 Bos taurus Secreted 1 0 4.3 ± 1.7 74 ± 12 -4.7
2.1.25.03. Enterocin 7A 2m5z Enterococcus faecalis Secreted 0 0 4.4 ± 0.3 57 ± 3 -5.3
2.4.35.01. 8R-Lipoxygenase, N-terminal domain 1u5u Plexaura homomalla Eukaryo. plasma 1 0 3.1 ± 0.3 72 ± 3 -10.4
2.2.11.01. Synaptotagmin-7 3n5a Mus musculus Vesicle 1 0 2.2 ± 2.3 30 ± 12 -4.1
2.2.34.01. Conotoxin TVIIA 1eyo Conus tulipa (Fish-hunting cone snail) Secreted 1 0 2.2 ± 0.7 74 ± 9 -4.6
2.1.01.01. Snake phospholipase A2, acidic 2h4c Daboia russellii siamensis Secreted 1 0 5.7 ± 1.1 88 ± 10 -9.0
3.1.05.01. Antimicrobial peptide RP-1 2rlg Designed proteins Undefined 1 0 5.9 ± 4.2 75 ± 4 -5.0
1.2.32.01. Cytochrome P450 2D6, conformation 3 3qm4 Homo sapiens Endoplasm. reticulum 1 0 9.0 ± 1.4 35 ± 11 -9.3
2.4.16.01. Neurotoxin 2 1jza Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.7 68 ± 15 -5.6
3.2.05.02. Caulonodin 2mlj Caulobacter sp. Secreted 1 0 2.4 ± 1.7 87 ± 15 -5.0
2.1.40.01. Protein unc-13 homolog A, MHD domain 3swh Rattus norvegicus Eukaryo. plasma 1 0 6.6 ± 3.0 27 ± 12 -6.8
2.3.14.01. Phosphatidylinositol transfer protein PDR16 4fmm Saccharomyces cerevisiae Endoplasm. reticulum 1 0 9.9 ± 2.6 78 ± 19 -13.9
2.4.16.04. Defensin-like protein 1 1ayj Raphanus sativus Secreted 1 0 11.0 ± 1.9 39 ± 19 -7.4
2.4.16.02. Coprisin 2ln4 Copris tripartitus Secreted 1 0 4.5 ± 0.6 42 ± 4 -5.3
2.3.06.01. Acetylcholinesterase, complex with fasciculin-2 4bdt Homo sapiens Eukaryo. plasma 2 0 10.7 ± 0.8 56 ± 3 -11.6
1.1.01.03. Glucagon-like peptide 1 receptor, extracellular domain 5e94 Homo sapiens Eukaryo. plasma 1 0 3.4 ± 10.0 36 ± 6 -7.5
2.1.21.04. Matrix protein p19 1a6s Rous sarcoma virus Viral 1 0 3.1 ± 2.7 89 ± 14 -3.6
3.1.11.01. Peptide YY 1ru5 Sus scrofa Secreted 1 0 5.1 ± 1.2 83 ± 3 -5.3
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 1 2gek Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 3.4 ± 2.6 85 ± 5 -5.7
2.1.01.01. Phospholipase A2 homolog 1ppa Agkistridon piscivorus Secreted 1 0 1.2 ± 0.9 85 ± 8 -4.5
2.4.06.04. STAR-related bacterial protein 3ggn Deinococcus radiodurans Undefined 1 0 5.2 ± 1.6 53 ± 8 -4.1
1.2.03.03. Myelin protein P0 1neu Rattus norvegicus Eukaryo. plasma 1 0 5.4 ± 1.8 70 ± 8 -6.6
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 4 3zg2 Trypanosoma cruzi Endoplasm. reticulum 1 0 5.8 ± 1.0 62 ± 4 -9.0
2.3.06.03. Gastric lipase, open (active) state 1k8q Canis lupus familiaris Secreted 1 0 7.2 ± 0.5 78 ± 6 -12.6
2.3.06.17. Phosphatidylcholine-sterol acyltransferase, structure 2 4xwg Homo sapiens Secreted 1 0 3.7 ± 0.7 37 ± 4 -6.1
2.3.06.05. Carboxylesterase 2 1auo Pseudomonas fluorescens Bact. Gram-neg inner 1 0 1.7 ± 3.0 33 ± 21 -3.4
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 2 3c6e Dengue virus Viral 1 0 2.9 ± 2.7 42 ± 5 -3.6
3.2.08.01. Peptide 35-42, alternate polymorph II 2y3l Homo sapiens Secreted 4 0 2.7 ± 1.4 78 ± 8 -6.0
1.2.39.01. Leucyl-cystinyl aminopeptidase, structure 1 5c97 Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.0 76 ± 3 -7.6
2.4.11.01. Viscotoxin A1 3c8p Viscum album Secreted 1 0 2.3 ± 0.9 45 ± 7 -4.9
3.2.01.09. Chignolin 5awl Designed proteins Undefined 1 0 2.6 ± 2.1 77 ± 28 -2.8
2.1.51.01. Protein farnesyltransferase/geranylgeranyltransferase 2h6f Homo sapiens Eukaryo. plasma 2 0 4.5 ± 1.5 87 ± 6 -6.5
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 2 4ph7 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.5 ± 0.9 75 ± 2 -6.4
3.1.11.01. Neuropeptide Y-pancreatic polypeptide hybrid 1tz4 Sus scrofa Secreted 1 0 5.1 ± 1.0 88 ± 8 -6.1
2.1.07.01. Nonaheme cytochrome c 1duw Desulfovibrio desulfuricans Bact. Gram-neg inner 1 0 5.1 ± 0.4 87 ± 10 -4.9
2.1.02.01. 12S-Lipoxygenase 3d3l Homo sapiens Eukaryo. plasma 1 0 5.0 ± 0.6 51 ± 3 -9.0
1.2.22.01. Apoptosis regulator Bcl-2 1g5m Homo sapiens Mitochon. outer 1 0 4.2 ± 1.4 33 ± 11 -6.6
2.2.56.01. Beta-2-glycoprotein 1 3op8 Homo sapiens Secreted 1 0 4.2 ± 1.8 47 ± 10 -6.1
2.4.25.01. N-alpha-acetyltransferase 60, structure 1 5hgz Homo sapiens Golgi 1 0 5.7 ± 1.1 41 ± 7 -8.5
2.2.34.05. Tachystatin-A2 1cix Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 3.9 ± 2.9 65 ± 14 -4.7
3.4.02.02. Mersacidin, structure in DPC micelles 1mqy Bacillus sp. Secreted 1 0 5.3 ± 0.9 90 ± 12 -6.1
1.2.39.02. Matrilysin, structure 2 2mzi Homo sapiens Secreted 1 0 3.5 ± 0.5 71 ± 4 -7.7
2.2.42.01. Matrix protein 2vqp Human respiratory syncytial virus Eukaryo. plasma 1 0 2.9 ± 1.1 86 ± 10 -6.1
3.1.28.04. Temporin-A 2maa Rana temporaria Secreted 1 0 7.2 ± 0.5 66 ± 7 -8.4
2.2.26.01. LM-5 FYVE domain 1z2q Leishmania major Endosome 1 0 1.5 ± 1.5 22 ± 19 -3.4
2.2.28.01. Tachycitin 1dqc Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 4.5 ± 0.8 78 ± 8 -5.6
2.2.04.01. Retinoid isomerohydrolase, conformation 3 4f30 Bos taurus Eukaryo. plasma 1 0 3.4 ± 1.4 61 ± 7 -10.9
2.4.11.01. Viscotoxin B 1jmp Viscum album Secreted 1 0 1.2 ± 1.4 52 ± 13 -3.2
2.2.36.01. Lactococcin 972 2lgn Lactococcus lactis Secreted 1 0 1.7 ± 2.8 56 ± 9 -3.3
2.1.18.01. Annexin VI 1avc Bos taurus Eukaryo. plasma 1 0 4.4 ± 1.0 83 ± 1 -8.1
2.1.13.01. Molt-inhibiting hormone 1j0t Marsupenaeus japonicus Secreted 1 0 4.1 ± 0.4 66 ± 6 -7.0
3.1.07.02. Juxtamembrane peptide (662-683) of protein gp160 4g6f Human immunodeficiency virus type 1 Endosome 1 0 4.9 ± 1.4 86 ± 0 -5.0
2.2.33.01. Antimicrobial peptide 1b 2lb7 Triticum kiharae (Wheat) Secreted 1 0 2.2 ± 0.7 89 ± 7 -2.5
1.2.39.01. Glutamyl aminopeptidase 4kxd Homo sapiens Eukaryo. plasma 1 0 3.3 ± 0.8 77 ± 2 -4.2
2.4.02.01. Epoxide Hydrolase 2bng Mycobacterium tuberculosis Bact. Gram-pos plas. 2 0 8.2 ± 0.6 88 ± 4 -24.0
3.1.15.02. Plantaricin-A 1ytr Lactobacillus plantarum Secreted 1 0 9.0 ± 0.5 78 ± 10 -9.4
2.1.01.01. Basic phospholipase A2 myotoxin III 5tfv Bothrops asper Secreted 1 0 6.1 ± 2.0 76 ± 5 -10.4
2.3.09.01. Cytidylyltransferase, first membrane-anchoring helix 1peh Rattus norvegicus Eukaryo. plasma 1 0 3.2 ± 0.6 90 ± 2 -5.0
2.3.16.05. ATPase Get3, homodimer 3a36 Saccharomyces cerevisiae Endoplasm. reticulum 2 0 5.6 ± 3.0 66 ± 10 -6.6
2.1.01.01. Phospholipase A2, group IB 1g4i Bos taurus Secreted 1 0 1.9 ± 0.5 87 ± 4 -7.4
3.4.01.01. Contryphan-Lo 2m6h Conus loroisii Secreted 1 0 3.3 ± 0.8 89 ± 14 -5.4
2.3.10.01. Peptidoglycan biosynthesis glycosyltransferase MurG, conformation 2 1f0k Escherichia coli Bact. Gram-neg inner 1 0 5.3 ± 1.2 55 ± 7 -8.6
2.1.02.01. Arachidonate 15-lipoxygenase 2p0m Oryctolagus cuniculus Eukaryo. plasma 1 0 8.6 ± 0.1 87 ± 5 -14.3
1.1.71.01. Legionalla phosphoinositide phosphatase, SidP 4jza Legionella pneumophila Vacuole 1 0 2.6 ± 1.7 57 ± 7 -5.6
3.1.31.01. Dermcidin, structure 1 2ksg Homo sapiens Secreted 1 0 4.7 ± 1.4 45 ± 6 -7.0
2.1.29.01. Apolipoprotein E 1ya9 Mus musculus Secreted 1 0 1.6 ± 1.4 85 ± 11 -4.1
3.1.29.02. Indolicidin, with P->A substitution 1hr1 Designed proteins Undefined 1 0 5.4 ± 4.0 84 ± 9 -8.3
2.2.20.01. Rho guanine nucleotide exchange factor 4 2dx1 Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.2 80 ± 10 -3.6
1.2.32.01. Cytochrome P450 2B4, open state 3 3r1b Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.7 ± 0.0 43 ± 5 -9.8
2.2.34.11. Cycloviolacin O1 1df6 Viola odorata Secreted 1 0 4.1 ± 1.2 63 ± 19 -5.9
2.1.60.03. Natrin-1 1xx5 Naja atra Secreted 1 0 2.6 ± 2.4 60 ± 49 -5.2
2.2.20.01. PH domain of TAPP1 1eaz Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.6 87 ± 14 -3.0
2.1.21.01. Influenza virus matrix protein M1, structure 1 1aa7 Influenza virus Viral 2 0 2.6 ± 0.8 89 ± 4 -5.6
2.2.34.02. U1-theraphotoxin-Hh1a 1i25 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.6 ± 0.2 79 ± 1 -5.1
3.1.07.09. Membrane fusion protein p15 2mns Baboon orthoreovirus Eukaryo. plasma 1 0 9.3 ± 7.0 86 ± 4 -9.4
2.3.06.09. Cutinase-like protein 2czq Cryptococcus sp. Secreted 1 0 4.9 ± 1.3 54 ± 16 -9.0
2.3.24.02. Hydrolase 3n1u Legionella pneumophila Undefined 4 0 5.6 ± 0.6 90 ± 1 -10.8
3.1.18.01. Delta-hemolysin 1dtc Staphylococcus aureus Secreted 1 0 3.2 ± 2.2 87 ± 19 -8.5
2.3.07.01. Endoglucanase 1vho Thermotoga maritima Undefined 1 0 5.4 ± 0.2 89 ± 1 -7.0
2.3.16.06. ADP-ribosylation factor-like protein 5A 1z6y Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.9 66 ± 15 -4.0
2.2.39.01. Toxin B 1txa Ophiophagus hannah Secreted 1 0 2.6 ± 1.5 51 ± 16 -5.6
2.2.32.01. ADP-ribosylating toxin CARDS, full-length 4tlw Mycoplasma pneumoniae Secreted 1 0 1.5 ± 1.4 47 ± 2 -4.8
2.2.60.01. Matrix protein VP40 1es6 Zaire ebolavirus Viral 1 0 2.1 ± 0.5 80 ± 3 -6.7
3.2.06.01. Growth-blocking peptide, long form 2eqt Pseudaletia separata (Oriental armyworm) Secreted 1 0 4.1 ± 1.4 59 ± 8 -5.7
3.1.04.06. Amyloidogenic peptide (248-286) of prostatic acid phosphatase 2l3h Homo sapiens Eukaryo. plasma 1 0 4.5 ± 2.7 86 ± 0 -4.2
2.2.12.01. Lymphocyte antigen 96, structure 1 2e56 Homo sapiens Secreted 1 0 3.6 ± 0.7 68 ± 4 -6.7
3.1.04.07. Peptide (70-94) of antifreeze protein Afp1 2lq1 Glaciozyma antarctica Undefined 1 0 6.2 ± 4.3 87 ± 1 -8.8
2.3.12.01. Myotubularin-related protein 2, dimer 1m7r Homo sapiens Eukaryo. plasma 2 0 1.4 ± 0.3 89 ± 0 -6.4
2.4.04.01. Type II inositol 1,4,5-trisphosphate 5-phosphatase 4cml Homo sapiens Endoplasm. reticulum 1 0 4.6 ± 1.1 48 ± 9 -5.1
2.3.06.07. Lipase 1qge Pseudomonas glumae Secreted 1 0 3.7 ± 0.9 24 ± 3 -7.7
2.3.19.01. Toxin A 4r04 Clostridium difficile Secreted 1 0 3.2 ± 2.4 74 ± 2 -6.7
1.2.54.01. Dihydroorotate dehydrogenase 1d3h Homo sapiens Mitochon. inner 1 0 3.4 ± 0.8 55 ± 6 -10.1
2.4.44.01. Membrane-associated protein VP24, with karyopherin 4u2x Zaire ebolavirus Viral 2 0 4.5 ± 2.1 33 ± 15 -4.3
2.2.45.02. Pectate lyase A 1pe9 Erwinia chrysanthemi Secreted 1 0 2.7 ± 0.4 81 ± 3 -6.4
2.4.43.01. Cell wall anchor protein of the T6SS system 4b62 Pseudomonas aeruginosa Bact. Gram-neg outer 1 0 2.8 ± 2.5 46 ± 36 -4.6
2.3.16.06. ADP-ribosylation factor 1 (ARF1) 2k5u Saccharomyces cerevisiae Golgi 1 0 2.9 ± 1.6 24 ± 18 -5.5
2.4.16.01. Alpha-like toxin CsEv5 1i6f Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.4 ± 1.3 59 ± 4 -5.8
3.1.05.03. Antimicrobial peptide PaDBS1R1 2n9r Designed proteins Undefined 1 0 5.6 ± 1.0 83 ± 6 -8.3
1.2.42.01. UDP-2,3-diacylglucosamine hydrolase 5b49 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 9.9 ± 1.9 42 ± 16 -4.9
2.3.16.07. Ras-related C3 botulinum toxin substrate 1 2p2l Homo sapiens Eukaryo. plasma 1 0 3.2 ± 0.8 58 ± 2 -5.2
2.1.04.01. Prostaglandin G/H synthase 2 5f19 Homo sapiens Endoplasm. reticulum 2 0 6.2 ± 1.0 90 ± 1 -33.7
3.1.19.01. Cephaibol B 1ob6 Acremonium tubakii Secreted 1 0 15.0 ± 5.0 42 ± 17 -15.3
2.2.34.02. Protoxin-II 5o0u Thrixopelma pruriens Secreted 1 0 4.8 ± 3.8 60 ± 2 -8.5
2.1.50.01. Phosphate transport system protein phoU homolog 2 1sum Thermotoga maritima Bact. Gram-neg inner 1 0 4.9 ± 2.1 68 ± 4 -4.3
2.3.13.04. Phospholipid hydroperoxide glutathione peroxidase 5l71 Mus musculus Mitochon. inner 1 0 7.1 ± 1.8 83 ± 14 -5.1
2.2.01.01. F18 fimbrial adhesin AC, FedF 4b4q Escherichia coli Secreted 1 0 1.8 ± 2.6 81 ± 20 -3.4
1.2.04.01. Integrin alpha-L, cytoplasmic domain (1113-1170) 2k8o Homo sapiens Eukaryo. plasma 1 0 2.2 ± 0.7 65 ± 3 -3.7
1.2.54.01. Glycolate oxidase 1gox Spinacia oleracea Peroxisome 4 0 4.1 ± 0.0 90 ± 0 -18.5
3.1.29.01. Cathelicidin-3, peptide 121-151 2hfr Gallus gallus Secreted 1 0 3.1 ± 4.2 86 ± 1 -8.0
2.1.02.01. Arachidonate 5-lipoxygenase, complex with arachidonic acid 3v99 Homo sapiens Eukaryo. plasma 1 0 3.0 ± 2.3 88 ± 9 -2.5
2.1.01.01. Snake phospholipase A2 isoform 5, group I 1y75 Naja sagittifera Secreted 1 0 4.4 ± 0.7 81 ± 10 -5.7
2.2.34.02. Spiderine-1a, 108-165 2n86 Oxyopes takobius (Lynx spider) Secreted 1 0 5.8 ± 3.7 57 ± 6 -5.7
1.2.61.01. Mitochondrial inner membrane translocase subunit TIM50 4qqf Saccharomyces cerevisiae Mitochon. inner 1 0 5.4 ± 0.8 76 ± 1 -7.0
2.1.60.02. Lasiocepsin 2mbd Lasioglossum laticeps Secreted 1 0 0.6 ± 1.3 47 ± 15 -2.5
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 3 5fih Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.5 ± 0.6 89 ± 1 -5.3
3.1.25.01. Latarcin-2a (M-zodatoxin-Lt2a) 2g9p Lachesana tarabaevi (Spider) Secreted 1 0 8.5 ± 1.4 77 ± 9 -6.4
2.4.04.01. Sphingomyelinase C 2ddt Bacillus cereus Secreted 1 0 4.1 ± 1.1 59 ± 8 -7.6
2.2.39.01. Ancestral Mamba toxin 1 5mg9 Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 4.2 ± 1.2 49 ± 6 -8.0
2.2.26.01. Rabphilin-3A 1zbd Rattus norvegicus Eukaryo. plasma 2 0 3.8 ± 1.8 68 ± 15 -4.0
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 2 2wx2 Trypanosoma cruzi Endoplasm. reticulum 1 0 5.9 ± 5.9 63 ± 2 -6.2
2.1.01.01. Snake phospholipase A2, group II 1pp2 Crotalus atrox Secreted 1 0 3.7 ± 1.3 80 ± 7 -12.9
2.4.42.01. Bactericidal permeability-increasing protein 1bp1 Homo sapiens Secreted 1 0 1.5 ± 2.4 51 ± 17 -4.3
2.1.08.01. Cytochrome c2 1co6 Rhodopseudomonas viridis Bact. Gram-neg inner 1 0 1.4 ± 0.7 78 ± 10 -3.3
2.2.11.01. Synaptotagmin-1, C2B domain (Calcium bound) 1uov Rattus norvegicus Eukaryo. plasma 1 0 1.7 ± 1.8 36 ± 13 -3.7
1.2.46.01. Agnoprotein (1-71) 5nhq JC polyomavirus Endosome 1 0 7.0 ± 2.1 84 ± 3 -11.8
3.1.30.01. Lactoferrin-based peptide, 39-49 2gmc Homo sapiens Secreted 1 0 3.9 ± 1.7 79 ± 13 -4.6
1.2.38.01. Glycosyltransferase MtgA 3hzs Staphylococcus aureus Bact. Gram-pos plas. 1 0 7.0 ± 1.1 54 ± 9 -14.6
2.2.34.02. Jingzhaotoxin-11 2a2v Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.0 ± 1.8 74 ± 19 -4.6
2.1.24.01. Saposin C (peptide 311-391) 1sn6 Homo sapiens Lysosome 1 0 4.8 ± 1.1 82 ± 7 -7.1
2.1.10.01. Glycolipid transfer protein Het-c2 3kv0 Podospora anserina Eukaryo. plasma 1 0 8.3 ± 1.3 83 ± 5 -13.6
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 1 2q9f Homo sapiens Endoplasm. reticulum 1 0 2.8 ± 1.0 86 ± 7 -5.8
2.2.06.01. Complement component C8 gamma chain 1lf7 Homo sapiens Secreted 1 0 1.9 ± 2.2 43 ± 12 -2.6
3.4.12.02. Thiostrepton 1e9w Streptomyces azureus Secreted 1 0 7.3 ± 1.5 86 ± 15 -4.9
2.2.11.01. Protein kinase C epsilon 1gmi Rattus rattus Eukaryo. plasma 1 0 2.9 ± 1.2 46 ± 15 -5.9
2.4.10.01. Synapsin I 1auv Bos taurus Vesicle 1 0 1.9 ± 1.1 86 ± 11 -5.2
2.2.34.08. Agouti-signaling protein 1y7j Homo sapiens Secreted 1 0 3.8 ± 1.6 62 ± 7 -6.9
2.2.27.01. C1 domain of protein kinase C alpha 2eli Homo sapiens Eukaryo. plasma 1 0 2.1 ± 0.4 23 ± 4 -7.4
1.2.18.01. Sortase B 1rz2 Bacillus anthracis Bact. Gram-pos plas. 1 0 3.0 ± 0.6 82 ± 6 -5.8
2.1.01.01. Snake phospholipase A2, ammodytoxin A, group II 3g8g Vipera ammodytes ammodytes Secreted 1 0 4.1 ± 0.9 80 ± 6 -11.0
3.1.05.04. Distinctin 1xkm Designed proteins Undefined 2 0 3.9 ± 0.4 87 ± 2 -4.6
1.2.04.01. Integrin beta-3, 742-788, 747pY, in micelles 2ljd Homo sapiens Eukaryo. plasma 1 0 8.1 ± 0.6 44 ± 4 -7.6
2.2.02.02. HCV serine protease NS3 3p8n Hepatitis C virus Endoplasm. reticulum 2 0 8.7 ± 1.7 56 ± 8 -9.9
2.2.34.02. ACTX-HI:OB4219 1kqi Hadronyche infensa Secreted 1 0 5.2 ± 1.2 72 ± 15 -8.2
3.1.28.02. Neuromedin-B 1c98 Homo sapiens Secreted 1 0 4.3 ± 1.8 77 ± 11 -3.8
2.3.05.03. Glycerol-3-phosphate dehydrogenase (GlpD) 2qcu Escherichia coli Bact. Gram-neg inner 1 0 4.5 ± 1.5 74 ± 11 -8.4
2.2.06.02. Brain fatty acid binding protein 1fdq Homo sapiens Eukaryo. plasma 1 0 3.1 ± 1.4 51 ± 15 -4.9
2.3.06.01. Acetylcholinesterase 5x61 Anopheles gambiae (African malaria mosquito) Eukaryo. plasma 1 0 2.6 ± 1.5 37 ± 4 -4.0
3.2.02.02. Chi-conotoxin MrIB 1ieo Conus marmoreus Secreted 1 0 2.2 ± 1.1 45 ± 12 -1.9
2.3.10.03. Heptosyltransferase WaaC 2h1h Escherichia coli Bact. Gram-neg inner 1 0 5.0 ± 1.1 67 ± 5 -9.1
2.2.06.02. Myelin P2 protein 1pmp Bos taurus Eukaryo. plasma 1 0 2.7 ± 1.3 61 ± 13 -6.1
2.1.64.01. AFMP4P 5j5k Aspergillus fumigatus Eukaryo. plasma 1 0 3.9 ± 1.9 73 ± 13 -6.1
1.2.43.01. Envelope glycoprotein, Dengue virus type 1 3g7t Dengue virus Viral 3 0 5.9 ± 0.9 1 ± 3 -12.2
3.1.20.01. Alpha-conotoxin GID 1mtq Conus geographus (Geography cone) Secreted 1 0 1.3 ± 2.5 78 ± 28 -2.4
3.2.01.02. Thanatin 8tfv Podisus maculiventris Secreted 1 0 3.7 ± 1.0 81 ± 4 -5.3
2.4.25.01. Uncharacterized N-acetyltransferase SSO0209 2x7b Sulfolobus solfataricus Undefined 1 0 3.9 ± 1.5 49 ± 6 -7.6
3.1.03.01. Myc box-dependent-interacting protein 1, membrane anchor helix (peptide 1-33) 2rnd Homo sapiens Eukaryo. plasma 1 0 4.0 ± 0.4 85 ± 2 -8.4
1.2.32.01. Cytochrome P450 2B6, conformation 3 4i91 Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 2.9 59 ± 11 -11.3
2.2.41.02. Sea anemone toxin IA 1atx Anemonia sulcata Secreted 1 0 4.5 ± 1.7 63 ± 12 -6.1
2.3.06.16. Lipase lip1 4opm Acinetobacter baumannii Secreted 1 0 1.8 ± 1.0 41 ± 3 -4.4
2.2.27.01. C1 domain of protein kinase C gamma 1tbn Rattus rattus Eukaryo. plasma 1 0 4.8 ± 1.6 42 ± 19 -3.7
2.1.21.02. Matrix protein p10, myristoylated, structure 2 2mxi Mason-Pfizer monkey virus Viral 1 0 3.8 ± 0.7 58 ± 3 -6.3
2.3.01.03. Alpha-amylase A 1wza Halothermothrix orenii Secreted 1 0 1.6 ± 0.4 80 ± 1 -6.7
1.2.50.01. Fragaceatoxin C, monomer 3lim Actinia fragacea (Strawberry anemone) Secreted 1 0 2.6 ± 0.8 46 ± 15 -5.0
2.2.03.02. Retropepsin 2q63 Human immunodeficiency virus type 1 Eukaryo. plasma 2 0 4.5 ± 0.4 89 ± 4 -10.4
2.4.11.01. beta-Purothionin 1bhp Triticum aestivum Secreted 1 0 2.9 ± 2.0 56 ± 19 -4.8
2.3.06.12. Lipase/esterase 3bjr Lactobacillus plantarum Secreted 1 0 2.1 ± 0.2 72 ± 5 -7.0
1.1.01.03. Ectodomain of G-protein coupled receptor Mth 1fjr Drosophila melanogaster Eukaryo. plasma 1 0 1.8 ± 1.5 56 ± 13 -4.3
1.2.33.02. Protoporphyrinogen oxidase 1sez Nicotiana tabacum Mitochon. inner 1 0 2.2 ± 1.0 50 ± 3 -7.0
2.4.09.01. T4 capsid assembly protease, gp21 5jbl Enterobacteria phage T4 Viral 5 0 3.6 ± 0.2 89 ± 0 -12.0
2.4.21.02. L-alanyl-D-glutamate peptidase 2vo9 Listeria phage A500 Secreted 1 0 3.1 ± 1.0 48 ± 4 -5.2
2.1.61.01. Muramidase Tse3-Tsi3 complex, conformation 3 3wa5 Pseudomonas aeruginosa Bact. Gram-neg outer 2 0 4.5 ± 1.4 84 ± 7 -4.6
1.2.39.03. Disintegrin and metalloproteinase domain-containing protein 10 2ao7 Bos taurus Golgi 1 0 3.1 ± 1.4 81 ± 6 -5.7
2.2.41.01. Defensin-like peptide 2/4 1d6b Ornithorhynchus anatinus Secreted 1 0 9.2 ± 0.7 73 ± 2 -11.0
2.4.08.01. Eosinophil cationic protein 1h1h Homo sapiens 1 0 3.5 ± 1.0 88 ± 6 -7.3
1.2.03.07. Cell adhesion molecule complex 3n1f Homo sapiens Eukaryo. plasma 2 0 5.2 ± 0.9 59 ± 4 -5.7
3.2.05.02. Microcin J25, peptide 38-58, cleaved after 47 1s7p Escherichia coli Secreted 1 0 4.7 ± 1.2 83 ± 18 -5.7
1.2.42.01. Sphingomyelin phosphodiesterase 5i85 Homo sapiens Secreted 1 0 7.1 ± 1.4 53 ± 2 -9.2
2.2.07.01. YceI-like protein 3q34 Pseudomonas syringae Bact. Gram-neg inner 2 0 1.0 ± 1.1 89 ± 2 -3.9
2.3.14.01. SEC14-like protein 2 (supernatant factor protein) 1o6u Homo sapiens Eukaryo. plasma 1 0 3.6 ± 1.4 62 ± 14 -4.9
2.1.01.01. Basic phospholipase A2 homolog 1 3t0r Bothrops moojeni Secreted 1 0 3.7 ± 1.6 86 ± 12 -2.6
2.4.07.01. PX domain of NADH oxidase (p40phox), ligand-bound 1h6h Homo sapiens Endosome 1 0 3.9 ± 2.0 55 ± 14 -6.0
3.1.15.01. Carnobacteriocin B2 1cw5 Carnobacterium maltaromaticum Secreted 1 0 6.5 ± 0.3 89 ± 5 -9.9
3.1.02.08. High affinity copper uptake protein 1, peptide 156-179 2ls4 Homo sapiens Eukaryo. plasma 1 0 4.9 ± 0.7 82 ± 10 -6.5
3.4.04.01. Daptomycin, Ca-free 1xt7 Streptomyces roseosporus Secreted 1 0 9.3 ± 3.9 10 ± 45 -6.4
2.2.34.12. Poneritoxin, omega-PONTX-Ae1a 2nbc Anochetus emarginatus Secreted 1 0 1.7 ± 1.8 72 ± 12 -2.5
1.2.54.01. Dihydroorotate dehydrogenase, 32-65 peptide 5tce Homo sapiens Mitochon. inner 1 0 3.7 ± 1.2 84 ± 7 -7.4
3.1.28.06. Magainin 2 2mag Xenopus laevis Secreted 1 0 10.1 ± 0.9 81 ± 14 -13.7
2.4.16.04. Flower-specific defensin D1, monomer 4ab0 Nicotiana alata (Winged tobacco) Secreted 1 0 3.5 ± 1.2 55 ± 13 -4.3
2.1.21.05. Matrix protein p15 1hek Equine infectious anemia virus Endosome 1 0 1.0 ± 2.8 76 ± 21 -2.6
3.1.10.01. Competence-stimulating peptide type 1 2a1c Streptococcus pneumoniae Secreted 1 0 4.8 ± 0.9 85 ± 20 -7.7
2.1.05.01. Squalene-hopene cyclase 2sqc Alicyclobacillus acidocaldarius Bact. Gram-pos plas. 2 0 7.4 ± 0.5 90 ± 1 -27.8
2.3.06.06. Lipase LipA 2qua Serratia marcescens Secreted 1 0 8.9 ± 0.2 59 ± 0 -37.5
3.2.01.01. Arenicin-3 5y0i Arenicola marina Secreted 1 0 3.0 ± 1.6 83 ± 5 -3.9
2.3.06.11. Monoglyceride lipase MGLL, closed ligand-bound conformation 3pe6 Homo sapiens Eukaryo. plasma 1 0 0.9 ± 3.0 54 ± 28 -2.7
2.3.04.01. Corticosteroid 11-beta-dehydrogenase, isozyme 1 1xu7 Homo sapiens Endoplasm. reticulum 2 0 7.9 ± 0.2 89 ± 1 -20.2
2.1.01.01. Snake phospholipase A2, group I, KPA2 1g2x Bungarus caeruleus Secreted 1 0 3.8 ± 1.5 84 ± 10 -5.4
2.2.34.02. Mu-cyrtautoxin-As1a 2m36 Apomastus schlingeri Secreted 1 0 1.7 ± 1.0 49 ± 35 -3.2
2.1.18.01. Annexin II 1w7b Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.2 87 ± 18 -3.8
3.1.03.02. Serine/threonine-protein kinase TOR1, FATC domain 2kit Saccharomyces cerevisiae Vacuole 1 0 6.3 ± 1.0 87 ± 18 -6.4
2.2.34.02. Omega-theraphotoxin-Gr1a 1koz Grammostola rosea (Chilean rose tarantula) Secreted 1 0 3.6 ± 0.8 68 ± 6 -6.5
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 5 4by0 Trypanosoma cruzi Eukaryo. plasma 1 0 4.8 ± 2.6 88 ± 7 -1.6
3.1.29.03. Tritrpticin 1d6x Sus scrofa Secreted 1 0 9.4 ± 2.6 81 ± 38 -8.1
2.3.06.17. Group XV phospholipase A2 4x90 Homo sapiens Lysosome 1 0 1.9 ± 0.5 56 ± 1 -7.3
2.2.06.02. Fatty acid-binding protein 2 2ftb Ambystoma mexicanum (Axolotl) Eukaryo. plasma 1 0 0.6 ± 2.0 77 ± 20 -1.7
1.2.32.01. Cytochrome P450 3A4, conformation 2 3nxu Homo sapiens Endoplasm. reticulum 1 0 9.3 ± 1.0 52 ± 12 -17.5
2.2.06.01. Retinol binding protein 1aqb Sus scrofa Secreted 1 0 4.1 ± 1.1 75 ± 14 -4.4
2.1.25.03. Enterocin 7B 2m60 Enterococcus faecalis Secreted 1 0 3.2 ± 1.6 53 ± 15 -3.8
2.2.21.01. Hisactophilin-1 1hce Dictyostelium discoideum Eukaryo. plasma 1 0 3.5 ± 1.1 60 ± 15 -1.6
2.2.20.01. PH domain of fermitin family homolog 3 5l81 Mus musculus Eukaryo. plasma 1 0 3.8 ± 2.2 59 ± 7 -4.2
2.2.12.04. AP-2 complex 2vj0 Rattus norvegicus Vesicle 1 0 2.6 ± 2.0 80 ± 11 -4.8
2.2.34.01. Conotoxin Gm9 1ixt Conus gloriamaris (Glory-of-the-Seas cone) Secreted 1 0 1.7 ± 1.7 85 ± 17 -3.0
3.1.06.02. Class A amphipathic helical peptide 2fq5 Designed proteins Undefined 1 0 6.5 ± 1.4 78 ± 6 -8.8
1.2.42.01. Glideosome-associated protein 50 3tgh Plasmodium falciparum Endoplasm. reticulum 1 0 4.2 ± 3.4 69 ± 3 -4.3
2.4.16.01. Beta-mammal toxin Cn2 2yc1 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.8 ± 1.1 68 ± 9 -3.8
1.2.50.01. Fragaceatoxin C, complex with lipids 4tsq Actinia fragacea (Strawberry anemone) Secreted 1 0 2.2 ± 0.9 38 ± 3 -15.5
2.3.24.01. Phosphatase YidA 1rkq Escherichia coli Undefined 1 0 2.5 ± 1.3 79 ± 9 -4.1
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 3ml9 Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.8 83 ± 2 -6.0
2.4.16.04. Defensin 1 1jkz Pisum sativum Secreted 1 0 3.5 ± 1.6 8 ± 19 -5.4
2.4.16.04. Defensin Lc-def 2lj7 Lens culinaris Secreted 1 0 2.2 ± 0.9 22 ± 10 -3.9
2.3.06.01. Butyryl cholinesterase 1p0i Homo sapiens Eukaryo. plasma 1 0 3.1 ± 0.8 43 ± 10 -6.4
2.1.21.02. Matrix protein p10, myristoylated, structure 1 2lpy Mason-Pfizer monkey virus Viral 1 0 3.2 ± 0.5 8 ± 6 -3.4
3.1.11.01. Pancreatic hormone 1ppt Meleagris gallopavo Secreted 1 0 3.5 ± 2.9 90 ± 27 -3.9
2.1.01.01. Phospholipase A2 isoform 4 1yxh Naja sagittifera Secreted 1 0 1.7 ± 0.5 81 ± 2 -5.2
2.4.06.04. STAR-related bacterial protein 1t17 Caulobacter crescentus Undefined 1 0 3.4 ± 0.7 63 ± 2 -8.1
2.1.59.01. AcrH-AopB chaperone-translocator complex 3wxx Aeromonas hydrophila Bact. Gram-neg inner 2 0 3.6 ± 2.2 51 ± 3 -7.4
2.4.07.01. NADPH oxidase organizer 1, PX domain 2l73 Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.9 72 ± 13 -5.1
2.3.06.10. Lipase 1jfr Streptomyces exfoliatus Secreted 1 0 5.0 ± 1.3 60 ± 10 -6.4
3.1.22.01. Antifungal peptide 2mp9 Cenchritis muricatus Secreted 1 0 1.2 ± 1.5 90 ± 26 -3.7
2.3.06.05. Carboxylesterase 3cn9 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 3.5 ± 2.1 11 ± 32 -4.1
2.3.13.02. Phosducin/Transducin beta-gamma complex, conformation 1 1a0r Bos taurus Eukaryo. plasma 3 0 2.3 ± 1.0 50 ± 4 -7.4
1.2.43.01. Envelope glycoprotein, West Nile virus, structure 3 3i50 West Nile virus Viral 1 0 6.3 ± 2.8 27 ± 19 -4.4
3.2.08.01. Peptide KLVFFA from amyloid beta, alternate polymorph II 3ow9 Homo sapiens Secreted 12 0 4.1 ± 1.4 88 ± 7 -12.8
2.3.02.01. Phospholipase C-beta isoform 3, complex with Galpha Q, structure 2 4qj3 Homo sapiens Eukaryo. plasma 2 0 3.2 ± 1.7 63 ± 10 -6.2
2.4.16.01. Neurotoxin BmK-M10 2kbk Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 1.7 ± 1.0 73 ± 14 -2.4
3.1.28.06. Magainin analogue 1 5cgn Designed proteins Undefined 2 0 6.1 ± 2.7 88 ± 6 -14.0
1.1.02.07. Bacteriochlorophyll c-binding protein, complex with chlorophyll 5lcb Chlorobium tepidum Bact. Gram-neg inner 6 0 13.0 ± 0.0 89 ± 0 -54.3
1.2.01.01. Receptor tyrosine-protein kinase erbB-3, extracellular domains 1m6b Homo sapiens Eukaryo. plasma 1 0 2.0 ± 1.6 45 ± 5 -3.9
3.1.11.02. Glucagon 1gcn Sus scrofa Secreted 1 0 5.3 ± 1.0 78 ± 12 -6.6
2.4.16.04. Defensin-like protein 2 2n2r Raphanus sativus Secreted 1 0 2.5 ± 1.7 31 ± 24 -4.2
1.1.63.01. Signal peptidase I 3iiq Escherichia coli Bact. Gram-neg inner 2 0 4.3 ± 0.5 57 ± 2 -10.2
2.3.18.01. Carnitine O-acetyltransferase 1ndb Mus musculus Mitochon. inner 1 0 3.0 ± 0.9 85 ± 6 -7.6
1.2.33.02. Monoamine oxidase B, monomer 1s3e Homo sapiens Mitochon. outer 2 0 7.3 ± 0.6 37 ± 1 -14.2
2.4.36.01. Transforming growth factor beta-1 3rjr Sus scrofa Secreted 2 0 5.8 ± 2.0 82 ± 16 -9.5
2.2.06.02. Intestinal fatty acid binding protein, structure 4 2mo5 Homo sapiens Eukaryo. plasma 1 0 1.9 ± 1.3 59 ± 6 -3.4
2.4.25.01. N-alpha-acetyltransferase 60, structure 2 5hh0 Homo sapiens Golgi 1 0 5.2 ± 0.0 46 ± 1 -10.7
2.2.41.02. Toxin CgNa 2h9x Condylactis gigantea (Giant Caribbean anemone) Secreted 1 0 3.6 ± 1.6 70 ± 15 -2.7
3.2.08.01. Amyloid beta A4 protein, peptide 672-711 2lnq Homo sapiens Eukaryo. plasma 8 0 6.3 ± 2.0 88 ± 0 -15.5
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 5frb Aspergillus fumigatus Endoplasm. reticulum 1 0 11.8 ± 0.5 59 ± 1 -13.2
3.4.02.02. Mersacidin, structure of lipid II bound peptide in DPC micelles 1mqz Bacillus sp. Secreted 1 0 4.2 ± 2.8 83 ± 15 -4.2
1.2.39.02. Matrilysin, structure 3 2mzh Homo sapiens Secreted 1 0 2.2 ± 1.6 67 ± 22 -6.4
2.3.16.10. Tetraacyldisaccharide 4-kinase 4ehx Aquifex aeolicus Bact. Gram-neg inner 1 0 8.0 ± 1.1 69 ± 3 -13.9
3.2.01.09. Cyclic beta-hairpin peptide 2m7i Designed proteins Secreted 1 0 2.0 ± 0.5 84 ± 8 -4.1
2.4.07.01. PX domain of sorting nexin-17 (SNX17) 3fog Homo sapiens Endosome 1 0 3.4 ± 1.0 69 ± 12 -4.9
2.2.28.02. Scarabaecin 1iyc Oryctes rhinoceros (Coconut rhinoceros beetle) Secreted 1 0 3.7 ± 2.3 90 ± 23 -5.0
2.4.11.01. Viscotoxin A2 1jmn Viscum album Secreted 1 0 2.3 ± 0.3 63 ± 8 -3.3
2.1.19.01. Nigellin 2nb2 Nigella sativa Secreted 1 0 4.7 ± 2.2 69 ± 12 -4.4
2.1.18.01. Annexin D1 1ycn Arabidopsis thaliana Eukaryo. plasma 1 0 2.3 ± 1.1 78 ± 14 -3.4
2.1.24.01. Saposin-like protein 5 2jsa Caenorhabditis elegans Secreted 1 0 1.8 ± 2.2 47 ± 0 -3.7
3.2.01.07. Cys-free protegrin analogue 2mq2 Designed proteins Secreted 1 0 1.3 ± 1.1 61 ± 19 -3.5
3.1.07.02. Juxtamembrane peptide (651-677) of protein gp160 2me2 Human immunodeficiency virus type 1 Endosome 1 0 7.0 ± 1.1 82 ± 7 -13.1
2.1.31.01. Colicin M, alternative orientation 2xmx Escherichia coli Secreted 1 0 2.4 ± 2.3 82 ± 4 -4.8
2.3.19.01. Alpha-toxin 2vk9 Clostridium novyi Secreted 1 0 3.2 ± 1.0 80 ± 2 -5.2
3.1.28.04. Esculentin-1A, structure 2 5xdj Pelophylax esculentus Secreted 1 0 7.2 ± 1.2 76 ± 8 -5.4
2.3.09.01. Cytidylyltransferase, second membrane-anchoring helix 1pei Rattus norvegicus Eukaryo. plasma 1 0 4.9 ± 1.0 83 ± 11 -8.2
3.1.07.05. Nonstructural protein 5a, segment 1973-2003 1r7g Human hepatitis C virus Endoplasm. reticulum 1 0 5.3 ± 0.9 90 ± 5 -15.1
2.1.01.01. Phospholipase A2, group IB 4p2p Sus scrofa Secreted 1 0 3.3 ± 0.8 89 ± 7 -8.6
3.2.05.02. Astexin-3 2m8f Asticcacaulis excentricus Secreted 1 0 6.2 ± 1.1 64 ± 28 -5.9
3.1.33.01. Stage V sporulation protein M 2mvh Bacillus subtilis Vacuole 1 0 6.3 ± 1.0 90 ± 4 -9.9
2.1.29.05. Apolipoprotein C-III 2jq3 Homo sapiens Secreted 1 0 2.9 ± 1.4 85 ± 0 -5.6
2.1.18.01. Annexin 4mdv Schistosoma mansoni Eukaryo. plasma 1 0 3.7 ± 0.8 77 ± 9 -5.9
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2 2w8d Bacillus subtilis Bact. Gram-pos plas. 1 0 0.0 ± 6.0 83 ± 58 -1.6
2.3.06.08. Pancreatic lipase-related protein 2 2oxe Homo sapiens Secreted 1 0 10.2 ± 1.1 88 ± 8 -10.1
2.2.34.11. Kalata B1, all-D analogue 2jue Designed proteins Undefined 1 0 3.7 ± 1.0 82 ± 17 -5.5
2.2.20.01. RAC-gamma serine/threonine-protein kinase 2x18 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.1 53 ± 4 -3.8
2.2.34.11. Cycloviolacin O1 1vb8 Viola hederacea Secreted 1 0 6.9 ± 1.0 88 ± 17 -9.7
2.1.60.03. Cysteine-rich secretory protein 2 2a05 Mus musculus Secreted 1 0 1.4 ± 1.8 52 ± 133 -2.8
2.2.20.01. Rac-alpha serine/threonine kinase 1unq Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.0 67 ± 18 -3.9
3.1.07.02. Paramyxovirus sv5 fusion protein core 1svf Simian virus 5 Viral 6 0 8.4 ± 0.9 0 ± 11 -10.7
2.2.34.02. U1-theraphotoxin-Ba1b 2kgh Brachypelma ruhnaui (Mexican golden redrump tarantula) Secreted 1 0 1.9 ± 2.5 83 ± 25 -1.9
1.1.73.01. TrbI protein 2bhv Helicobacter pylori Bact. Gram-neg outer 1 0 3.1 ± 1.3 42 ± 11 -6.4
2.3.19.03. Galactofuranosyl transferase GlfT2 4fix Mycobacterium tuberculosis Bact. Gram-pos plas. 4 0 3.6 ± 0.0 90 ± 0 -24.8
2.2.34.11. Circulin B 2eri Chassalia parviflora Secreted 1 0 5.0 ± 1.0 69 ± 20 -8.4
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase 4fdo Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 4.3 ± 1.1 67 ± 4 -5.3
3.1.29.01. Antimicrobial protein CAP18, segment 135-166 1lyp Oryctolagus cuniculus Secreted 1 0 7.4 ± 1.0 87 ± 9 -15.6
2.4.27.01. Gamma-glutamylaminecyclotransferase 1vkb Mus musculus Undefined 1 0 2.3 ± 0.7 72 ± 4 -4.8
2.4.15.01. Protein Nef, complex with T-cell surface glycoprotein CD3 zeta chain 3ik5 Simian immunodeficiency virus Eukaryo. plasma 2 0 3.1 ± 0.5 78 ± 7 -4.5
2.2.39.02. Dendroaspin (mambin) 1drs Dendroaspis jamesoni kaimosae Secreted 1 0 3.3 ± 1.5 87 ± 12 -6.5
2.2.32.01. ADP-ribosylating toxin CARDS, nicked 4tlv Mycoplasma pneumoniae Secreted 1 0 3.7 ± 1.1 44 ± 10 -4.8
2.1.18.01. Annexin IV, monomeric state 1ann Bos taurus Eukaryo. plasma 1 0 2.2 ± 1.0 77 ± 3 -6.0
2.1.21.01. Influenza virus matrix protein M1, structure 2 4pus Influenza virus Viral 2 0 2.3 ± 1.6 81 ± 3 -9.4
3.1.12.01. Sarafotoxin-I3 2lde Atractaspis microlepidota microlepidota Secreted 1 0 4.2 ± 3.6 86 ± 8 -2.8
3.1.02.02. S4-S5 linker peptide (532-551) of HERG K+ channel 2le7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.4 69 ± 9 -5.0
3.1.14.01. Scyliorhinin-1 2nou Scyliorhinus canicula (Small-spotted catshark) Secreted 1 0 8.6 ± 1.4 81 ± 10 -9.1
3.1.04.07. Peptide (119-148) of antifreeze protein Afp1 2lq2 Glaciozyma antarctica Undefined 1 0 1.7 ± 2.4 84 ± 6 -8.6
2.4.03.01. Tubby protein homolog 1s31 Homo sapiens Eukaryo. plasma 1 0 6.8 ± 1.0 71 ± 2 -7.6
3.1.07.06. NS2 protease, segment 766-789 of polyprotein 2lzq Hepatitis GB virus Endoplasm. reticulum 1 0 3.2 ± 2.1 88 ± 1 -5.9
2.3.06.07. Lipase 5lip Burkholderia cepacia Secreted 1 0 9.0 ± 1.0 46 ± 2 -30.6
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3a 5ebe Homo sapiens Secreted 1 0 2.6 ± 0.6 38 ± 1 -7.0
2.2.21.02. Fibroblast growth factor 19 1pwa Homo sapiens Secreted 1 0 2.9 ± 1.5 48 ± 21 -4.7
2.4.07.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Homo sapiens Golgi 1 0 2.5 ± 1.3 56 ± 16 -4.8
2.4.16.01. Kurtoxin 1t1t Parabuthus transvaalicus Secreted 1 0 3.8 ± 0.8 88 ± 11 -5.9
3.2.10.01. PawS derived peptide 22 2ndl Designed proteins Undefined 1 0 8.6 ± 2.1 64 ± 9 -5.3
2.3.05.05. RabGDI protein 3p1w Plasmodium falciparum Eukaryo. plasma 1 0 6.6 ± 1.4 47 ± 3 -6.8
3.1.19.01. Cephaibol C 1ob7 Acremonium tubakii Secreted 1 0 15.0 ± 2.1 55 ± 21 -15.0
1.3.25.01. LukGH complex 5k59 Staphylococcus aureus Secreted 2 0 4.7 ± 2.8 41 ± 15 -5.4
2.2.12.05. Glucans biosynthesis protein G 1txk Escherichia coli Bact. Gram-neg inner 1 0 2.3 ± 0.7 80 ± 8 -5.1
2.3.17.02. Folic acid synthesis protein FOL1 2bmb Saccharomyces cerevisiae Mitochon. inner 1 0 2.0 ± 0.6 31 ± 2 -5.8
3.1.19.01. Samarosporin I 4g13 Samarospora rostrup Secreted 1 0 16.7 ± 1.5 64 ± 14 -15.3
1.2.04.01. Integrin alpha-M, cytoplasmic helix (1129-1152) 2lke Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.8 73 ± 12 -3.6
2.1.14.01. Peroxisomal targeting signal 1 receptor, complex with sterol carrier protein 2 2c0l Homo sapiens Peroxisome 2 0 3.1 ± 2.5 85 ± 35 -5.5
3.1.29.01. Cathelicidin-1 2amn Gallus gallus Secreted 1 0 5.0 ± 3.3 68 ± 4 -8.7
2.1.08.01. Cytochrome c6 1c6s Thermosynechococcus elongatus Thylakoid 1 0 0.4 ± 1.7 89 ± 16 -1.3
2.1.01.01. Snake phospholipase A2 RV-7, group II 1oqs Daboia russellii siamensis Secreted 1 0 2.7 ± 1.1 87 ± 8 -7.9
3.1.19.01. Alamethicin 1amt Trichoderma viride Secreted 1 0 10.9 ± 2.9 74 ± 13 -17.1
2.1.29.01. Apolipoprotein A-I 2lem Mus musculus Secreted 1 0 2.7 ± 1.7 79 ± 2 -4.3
3.1.07.04. Juxtamembrane peptide of hepatis C virus E1 glycoprotein (314-342) 2knu Hepatitis C virus Endosome 1 0 5.3 ± 0.9 82 ± 6 -5.9
2.2.41.01. Reptilian defensin 2b5b Caretta caretta Secreted 1 0 1.5 ± 0.4 73 ± 1 -4.1
2.3.02.03. Sphingomyelinase D 1 1xx1 Loxosceles laeta Secreted 1 0 8.1 ± 1.0 70 ± 8 -10.6
3.2.01.07. Protegrin-5 2nc7 Sus scrofa Secreted 1 0 2.3 ± 1.2 87 ± 6 -2.4
2.1.01.01. Snake phospholipase A2, group II, acidic 1bk9 Agkistrodon halys pallas Secreted 1 0 7.3 ± 0.3 87 ± 3 -11.4
3.1.11.05. Parathyroid hormone 1et1 Homo sapiens Secreted 1 0 2.1 ± 0.5 85 ± 3 -5.6
2.1.08.01. Mono-heme c-type cytochrome ScyA 1kx7 Shewanella putrefaciens Bact. Gram-neg inner 1 0 1.8 ± 1.1 72 ± 12 -3.2
2.2.20.01. PH domain of phospholipase C delta 1 1mai Rattus norvegicus Eukaryo. plasma 1 0 15.0 ± 1.8 22 ± 14 -17.8
3.1.07.01. Fusion peptide of spike glycoprotein (758-820) 5xjk Human SARS coronavirus Endosome 1 0 4.1 ± 1.4 82 ± 2 -10.9
3.1.30.01. Lactoferrin-based peptide, 21-67 1z6v Homo sapiens Secreted 1 0 1.7 ± 1.4 84 ± 3 -4.9
2.2.34.02. Omega-agatoxin-4A 1oav Agelenopsis aperta Secreted 1 0 4.0 ± 1.1 75 ± 14 -4.0
2.3.01.01. Glucosylceramidase 2vt0 Pan troglodytes Lysosome 1 0 2.3 ± 1.0 86 ± 5 -7.3
2.4.05.01. Uncharacterized protein 3bkr Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.4 ± 6.2 50 ± 73 -1.2
2.3.04.01. Corticosteroid 11-beta-dehydrogenase, isozyme 1 3g49 Cavia porcellus Endoplasm. reticulum 2 0 7.0 ± 0.5 90 ± 1 -15.9
2.2.12.01. Epididymal secretory protein E1 1nep Bos taurus Secreted 1 0 8.0 ± 1.4 73 ± 14 -4.6
3.4.12.02. Thiostrepton, epimer form 2l2y Streptomyces azureus Secreted 1 0 2.7 ± 2.9 29 ± 9 -5.3
2.1.08.01. Cytochrome c2 1cxa Rhodobacter sphaeroides Bact. Gram-neg inner 1 0 2.0 ± 1.2 88 ± 13 -4.3
2.2.11.01. Synaptotagmin-3 3hn8 Rattus norvegicus Eukaryo. plasma 1 0 4.0 ± 3.1 74 ± 19 -4.0
2.3.08.02. Cytosolic phospholipase A2, group IVA 1cjy Homo sapiens Vesicle 1 0 5.8 ± 1.0 70 ± 9 -9.9
3.4.06.01. Conomarphin 2jqc Conus marmoreus Secreted 1 0 4.1 ± 1.1 89 ± 12 -7.4
2.2.27.01. C1 domain of protein kinase C theta 2enn Homo sapiens Eukaryo. plasma 1 0 6.2 ± 1.9 89 ± 3 -7.5
1.2.18.01. Putative sortase 2wts Streptococcus pneumoniae Bact. Gram-pos plas. 1 0 5.1 ± 1.0 20 ± 3 -4.6
2.1.01.01. Snake phospholipase A2 homolog bothropstoxin-1, group II 3i03 Bothrops jararacussu Secreted 1 0 2.5 ± 0.5 76 ± 5 -10.6
3.1.28.05. Aurein 1.2 analogue 2f3a Designed proteins Undefined 1 0 3.0 ± 1.6 88 ± 24 -11.7
1.2.04.01. Integrin beta-3, 742-788, biphosphorylated (747pY, 759pY) 2lje Homo sapiens Eukaryo. plasma 1 0 4.0 ± 0.5 74 ± 2 -7.0
2.2.02.02. Hepatitis C virus NS3 protease 2o8m Hepatitis C virus Endoplasm. reticulum 4 0 5.0 ± 1.3 72 ± 8 -9.0
2.2.34.02. Atracotoxin-hvI 1vtx Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 8.3 ± 1.0 89 ± 10 -9.4
3.1.21.02. Anoplin 2mjq Anoplius samariensis Secreted 1 0 5.6 ± 1.1 85 ± 8 -8.4
2.3.14.02. Uncharacterized protein 2q3l Shewanella loihica Bact. Gram-neg inner 1 0 6.0 ± 0.5 64 ± 4 -12.6
2.2.06.02. Epidermal fatty acid binding protein 4lkt Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.2 39 ± 7 -6.7
2.1.64.01. Envelope glycoprotein, ligand-binding domain 1 5e7x Talaromyces marneffei Eukaryo. plasma 1 0 2.7 ± 2.2 55 ± 13 -4.4
3.1.07.02. Envelope glycoprotein gp41 2x7r Human immunodeficiency virus type 1 Viral 3 0 5.5 ± 1.1 0 ± 10 -10.9
3.1.20.01. Rho-conotoxin TIA 1ien Conus tulipa (Fish-hunting cone snail) Secreted 1 0 3.4 ± 1.6 73 ± 7 -3.5
2.3.10.03. LPS heptosyltransferase II, WaaF 1psw Escherichia coli Bact. Gram-neg inner 1 0 3.1 ± 1.1 58 ± 8 -5.6
2.2.06.02. Fatty acid-binding protein Sm14 1vyf Schistosoma mansoni Eukaryo. plasma 1 0 5.1 ± 1.2 42 ± 18 -5.2
1.2.43.03. Envelope glycoprotein B 3nw8 Human herpesvirus Viral 3 0 4.6 ± 0.0 1 ± 1 -11.7
3.1.20.01. Alpha-conotoxin CnIA 1b45 Conus consors (Singed cone) Secreted 1 0 0.8 ± 0.8 80 ± 20 -2.1
2.3.06.06. Triacylglycerol lipase 3g7n Penicillium expansum Secreted 1 0 3.8 ± 1.1 81 ± 14 -9.0
2.4.35.01. Catalase-related protein 3e4w Mycobacterium paratuberculosis Undefined 2 0 9.6 ± 1.3 49 ± 6 -13.4
3.1.04.01. Protein STE5, peptide 44-67 2kgn Saccharomyces cerevisiae Eukaryo. plasma 1 0 6.4 ± 0.9 84 ± 7 -9.8
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 1 4b2z Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.3 ± 1.3 86 ± 6 -4.6
2.2.41.02. Anthopleurin-A 1ahl Anthopleura xanthogrammica Secreted 1 0 3.7 ± 1.2 86 ± 11 -7.3
2.3.06.16. Putative epoxide hydrolase 5bov Klebsiella pneumoniae Secreted 1 0 5.7 ± 1.4 23 ± 10 -5.1
2.2.27.01. Diacylglycerol kinase delta 1r79 Homo sapiens Eukaryo. plasma 1 0 3.3 ± 1.6 34 ± 19 -4.9
1.2.45.02. Small hydrophobic protein, peptide 1-14 2nb7 Human respiratory syncytial virus Viral 1 0 4.1 ± 0.9 84 ± 6 -7.7
2.3.01.07. Chitinase A 1nh6 Serratia marcescens Secreted 1 0 2.7 ± 1.3 80 ± 5 -6.1
3.1.04.03. Viral protein R, peptide 50-82 1bde Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.8 ± 1.1 89 ± 24 -6.7
1.2.50.01. Sticholysin-1 2ks4 Stoichactis helianthus Secreted 1 0 2.3 ± 2.2 6 ± 24 -5.7
3.1.05.03. Peptide F 1pef Designed proteins Undefined 1 0 6.6 ± 1.3 85 ± 10 -7.8
1.2.32.01. Cytochrome P450 17A1 4r1z Danio rerio Endoplasm. reticulum 1 0 5.0 ± 1.2 83 ± 2 -6.5
2.4.11.01. Hellethionin D 1nbl Helleborus purpurascens Secreted 1 0 2.2 ± 0.9 45 ± 9 -7.4
2.3.06.19. PHB depolymerase PhaZ7, structure 2 4btv Pseudomonas lemoignei Secreted 1 0 1.0 ± 2.3 64 ± 35 -5.2
2.3.13.03. Thiol-disulfide interchange protein DsbA 1u3a Escherichia coli Bact. Gram-neg inner 1 0 2.2 ± 1.4 86 ± 8 -4.2
2.2.12.02. Rho GDP-dissociation inhibitor 1, complex with cell division control protein 42 1doa Homo sapiens Eukaryo. plasma 2 0 1.1 ± 1.3 87 ± 4 -3.1
2.1.21.02. Matrix protein p10 5hyb Mouse mammary tumor virus Viral 1 0 12.9 ± 10.0 73 ± 10 -9.4
2.3.33.01. Endo-beta-N-acetylglucosaminidase 2vtf Arthrobacter protophormiae Secreted 1 0 4.1 ± 0.7 52 ± 2 -6.5
2.3.05.06. Endothelin-converting enzyme 2 2pxx Homo sapiens Golgi 1 0 7.1 ± 1.3 37 ± 8 -8.4
2.2.41.01. Defensin-like peptide 1 1b8w Ornithorhynchus anatinus Secreted 1 0 1.8 ± 0.6 84 ± 2 -4.4
1.2.03.05. Prolactin receptor 3nce Homo sapiens Eukaryo. plasma 2 0 3.4 ± 1.5 68 ± 2 -5.7
3.2.05.02. Microcin J25, peptide 38-58 1q71 Escherichia coli Secreted 1 0 3.3 ± 3.2 75 ± 17 -5.2
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3a 5fc1 Mus musculus Secreted 1 0 2.3 ± 3.0 62 ± 17 -4.8
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1kcm Mus musculus Eukaryo. plasma 1 0 5.3 ± 1.4 59 ± 5 -11.0
1.2.32.01. Cytochrome P450 11B2, mitochondrial 4dvq Homo sapiens Mitochon. inner 1 0 4.8 ± 0.6 48 ± 4 -9.1
2.4.42.01. Latherin 3zpm Equus caballus Secreted 1 0 6.0 ± 0.4 75 ± 1 -8.0
1.3.17.02. BamB-BamA P3-5 complex 4xga Escherichia coli Bact. Gram-neg outer 2 0 6.9 ± 1.2 88 ± 38 -6.3
1.1.26.07. STAS domain of prestin 3llo Rattus norvegicus Eukaryo. plasma 1 0 5.4 ± 0.6 68 ± 4 -5.3
2.2.26.01. Early endosome antigen 1 (EEA1), monomer 1hyi Homo sapiens Endosome 1 0 3.0 ± 2.0 24 ± 17 -3.5
3.1.16.01. Lactococcin-G subunit alpha 2jpj Lactococcus lactis Secreted 1 0 5.8 ± 2.9 77 ± 3 -5.9
2.2.20.01. Fermitin family homolog 2 4f7h Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.4 72 ± 4 -4.2
3.4.04.01. Daptomycin, Ca-bound 1t5n Streptomyces roseosporus Secreted 1 0 8.6 ± 2.0 21 ± 24 -9.0
2.2.34.02. beta-TRTX-Pre1a toxin 5i1x Psalmopoeus cambridgei (Trinidad chevron tarantula) Secreted 1 0 5.0 ± 1.6 52 ± 12 -6.3
2.3.02.01. Phospholipase C-beta isoform 3, complex with Galpha Q, structure 1 3ohm Homo sapiens Eukaryo. plasma 2 0 7.5 ± 2.0 39 ± 5 -6.9
3.1.21.03. Melittin 2mlt Apis mellifera Secreted 1 0 15.0 ± 1.0 65 ± 11 -12.0
2.2.35.01. Listeriolysin O 4cdb Listeria monocytogenes Secreted 1 0 3.2 ± 0.0 30 ± 0 -6.0
3.1.07.01. Fusion peptide of E1 envelope glycoprotein (84-101) 2rsw Chikungunya virus Endosome 1 0 8.3 ± 0.6 57 ± 7 -6.9
3.1.10.01. Competence stimulating peptide 2i2h Streptococcus mutants Secreted 1 0 8.2 ± 0.5 74 ± 7 -12.5
2.3.06.10. Lipase 2fx5 Pseudomonas mendocina Secreted 1 0 5.5 ± 1.0 50 ± 5 -8.4
3.1.28.09. Pseudin-2, structure 2 2ncx Pseudis paradoxa Secreted 1 0 4.4 ± 4.4 85 ± 13 -9.2
2.1.02.01. Arachidonate 5-lipoxygenase 3o8y Homo sapiens Eukaryo. plasma 1 0 2.1 ± 1.0 89 ± 4 -3.8
2.1.01.01. Snake phospholipase A2, group I, isoform 1 1tc8 Bungarus caeruleus Secreted 1 0 3.1 ± 1.4 89 ± 11 -5.0
2.2.34.02. Beta-theraphotoxin-Tp1a 2m9l Thrixopelma pruriens Secreted 1 0 5.4 ± 0.7 73 ± 3 -6.6
2.2.07.01. Polyisoprenoid-binding protein 1wub Thermus thermophilus Bact. Gram-neg inner 1 0 2.9 ± 1.9 42 ± 13 -4.4
2.1.18.01. Annexin III 1axn Homo sapiens Eukaryo. plasma 1 0 2.7 ± 0.8 77 ± 11 -5.7
2.2.34.02. Mu-theraphotoxin-Hhn2b 1nix Haplopelma hainanum (Chinese bird spider) Secreted 1 0 3.6 ± 1.1 64 ± 5 -5.5
3.1.27.01. Pardaxin 2kns Pardachirus marmoratus Secreted 1 0 4.0 ± 0.7 84 ± 7 -11.1
2.2.11.01. Rabphilin-3A 2k3h Mus musculus Eukaryo. plasma 1 0 1.7 ± 2.1 78 ± 16 -4.1
2.1.36.01. Endoplasmic reticulum oxidoreductin 1rp4 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.0 ± 1.8 16 ± 9 -4.7
2.2.06.01. Retinol binding protein 1rbp Homo sapiens Secreted 1 0 3.5 ± 0.8 70 ± 6 -5.8
1.3.25.01. Gamma-hemolysin prepore, hetero-octamer (A+B) 4p1y Staphylococcus aureus Secreted 8 0 1.3 ± 1.0 85 ± 2 -7.8
1.2.17.02. Synaptobrevin homolog YKT6 3kyq Rattus norvegicus Vesicle 1 0 2.5 ± 2.0 53 ± 8 -4.9
2.2.34.02. Mu-theraphotoxin-Hhn2a 2jtb Haplopelma hainanum (Chinese bird spider) Secreted 1 0 3.4 ± 1.5 74 ± 12 -4.7
2.4.03.01. Tubby protein 3c5n Homo sapiens Eukaryo. plasma 1 0 3.4 ± 0.4 75 ± 5 -7.6
3.1.06.01. Apolipoprotein A-I, peptide 190-209 1odq Homo sapiens Undefined 1 0 3.3 ± 0.7 87 ± 4 -7.1
1.2.47.01. Nickel-cobalt-cadmium resistance protein NccX 4clv Alcaligenes xylosoxidans Bact. Gram-neg inner 1 0 3.1 ± 0.9 83 ± 0 -6.7
3.1.02.01. Beta-1 adrenergic receptor, peptide 345-359 1dep Meleagris gallopavo Eukaryo. plasma 1 0 4.4 ± 1.2 76 ± 16 -8.3
2.4.16.01. Alpha-like neurotoxin BmK-I 1djt Buthus martensii Secreted 2 0 3.8 ± 0.9 90 ± 15 -6.9
2.3.24.01. Phosphonoacetaldehyde hydrolase 1rdf Bacillus cereus Undefined 1 0 4.3 ± 0.9 68 ± 4 -5.1
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform 1e7u Sus scrofa Eukaryo. plasma 1 0 2.5 ± 0.9 85 ± 3 -4.7
2.3.06.08. Pancreatic lipase, complex with colipase from Pig 1lpb Homo sapiens Secreted 2 0 9.2 ± 0.4 89 ± 2 -24.2
2.4.16.08. Theromacin 2ln8 Hirudo medicinalis Secreted 1 0 3.7 ± 0.2 72 ± 3 -6.4
2.1.37.01. Erythrocyte membrane protein 1 2xu0 Plasmodium falciparum Eukaryo. plasma 1 0 3.3 ± 6.0 75 ± 45 -3.2
2.1.21.02. Matrix protein p10 2f76 Mason-Pfizer monkey virus Viral 1 0 3.9 ± 1.2 48 ± 5 -5.8
3.1.11.03. Obestatin 2jsi Mus musculus Secreted 1 0 2.0 ± 3.3 85 ± 13 -3.1
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 2 4nc9 Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 4.1 ± 1.1 69 ± 7 -7.9
2.1.24.01. Saposin-like domain of plant aspartic protease 3rfi Solanum tuberosum Secreted 1 0 5.6 ± 3.2 66 ± 3 -9.1
2.3.06.06. Lipase B, open state 1lbs Candida antarctica Secreted 1 0 3.7 ± 1.0 76 ± 6 -12.7
3.2.01.10. RCB-1 peptide 2mtm Ricinus communis Secreted 1 0 10.1 ± 3.0 37 ± 37 -8.4
2.3.06.05. Thermostable Esterase 3doh Thermotoga maritima Bact. Gram-neg inner 1 0 4.0 ± 2.0 84 ± 13 -4.4
2.3.13.02. Phosducin/Transducin beta-gamma complex, conformation 2 2trc Rattus norvegicus Eukaryo. plasma 3 0 2.2 ± 1.0 62 ± 10 -4.9
1.2.43.01. Envelope glycoprotein, West Nile virus, structure 4 3iyw West Nile virus Viral 1 0 6.6 ± 2.9 30 ± 15 -4.5
2.4.33.02. Collagenase 2y3u Clostridium histolyticum Secreted 1 0 3.0 ± 1.0 89 ± 4 -5.4
1.1.59.01. Membrane protease specific for a stomatin homolog, monomer 3bpp Pyrococcus horikoshii Archaebac. 1 0 4.0 ± 0.4 82 ± 5 -6.3
2.3.02.01. Phospholipase C-beta isoform 3, complex with Galpha Q, structure 3 4gnk Homo sapiens Eukaryo. plasma 2 0 5.2 ± 1.4 56 ± 3 -7.8
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 1 1zhx Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.9 90 ± 7 -5.0
2.4.16.01. Beta-insect excitatory toxin BmK IT-AP 1t0z Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 3.9 ± 1.2 79 ± 10 -7.2
3.1.28.06. Magainin analogue 2 5cgo Designed proteins Undefined 2 0 3.8 ± 0.9 89 ± 2 -10.8
1.1.02.07. Bacteriochlorophyll c-binding protein 2k37 Chlorobium tepidum Bact. Gram-neg inner 1 0 5.8 ± 0.2 87 ± 2 -17.8
1.2.01.01. Receptor tyrosine-protein kinase erbB-2 1n8y Rattus norvegicus Eukaryo. plasma 1 0 3.4 ± 3.0 53 ± 5 -4.2
3.1.11.03. Motilin 1lbj Homo sapiens Secreted 1 0 8.6 ± 1.6 51 ± 18 -4.9
2.2.34.07. Asteropsin F 2n2g Asteropus sp. Secreted 1 0 4.3 ± 1.7 60 ± 11 -3.4
2.3.18.01. Carnitine O-octanoyltransferase 1nm8 Homo sapiens Mitochon. inner 1 0 1.7 ± 3.0 67 ± 15 -5.3
2.1.24.01. Saposin-like protein Na-SLP-1 3s63 Necator americanus Secreted 1 0 2.2 ± 1.6 74 ± 10 -3.5
2.4.06.01. START and PH domains of collagen type IV alpha-3-binding protein 5jjd Homo sapiens Golgi 1 0 1.4 ± 2.6 48 ± 16 -4.4
2.4.16.04. Defensin-like protein 1 1gps Triticum aestivum Secreted 1 0 3.4 ± 1.3 22 ± 9 -3.9
1.2.32.01. Cytochrome P450 17A2 4r21 Danio rerio Endoplasm. reticulum 1 0 1.0 ± 10.0 70 ± 10 -2.4
3.4.02.03. Nisin-Lipid II complex in DMSO solution 1wco Lactococcus lactis Secreted 1 0 8.1 ± 1.0 90 ± 5 -8.0
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3b 5kar Mus musculus Secreted 1 0 0.8 ± 1.3 51 ± 4 -3.9
2.3.16.10. Tetraacyldisaccharide 4-kinase, complex with ADP/ATP 4ehy Aquifex aeolicus Bact. Gram-neg inner 1 0 7.9 ± 0.9 71 ± 4 -12.1
2.3.11.01. Ferrochelatase, conformation 2 (with porphyrin bound) 4klr Homo sapiens Mitochon. inner 2 0 1.3 ± 0.0 90 ± 1 -8.4
2.3.06.02. Antigen 85b 1f0n Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 3.7 ± 0.9 33 ± 7 -7.4
3.1.14.01. Neuropeptide gamma 2mce Oryctolagus cuniculus Secreted 1 0 8.4 ± 1.4 60 ± 10 -6.1
3.1.07.05. Nonstructural protein, membrane-bound domain 1fw5 Semiliki forest virus Endosome 1 0 7.9 ± 1.5 73 ± 17 -10.2
2.2.33.01. Antimicrobial peptide 2 1mmc Amaranthus caudatus (Inca-wheat) Secreted 1 0 1.6 ± 1.2 46 ± 9 -3.9
3.1.21.02. Mastoparan 2czp Vespa xanthoptera Secreted 1 0 5.2 ± 1.6 88 ± 16 -9.8
2.3.06.05. Esterase 5dwd Pelagibacterium halotolerans Secreted 1 0 3.1 ± 2.1 66 ± 20 -4.7
2.1.18.01. Annexin IV 2zhj Rattus norvegicus Eukaryo. plasma 1 0 4.1 ± 1.0 80 ± 1 -7.6
2.1.04.01. Prostaglandin H2 synthase-1 1q4g Ovis aries Endoplasm. reticulum 2 0 8.9 ± 0.4 90 ± 1 -43.4
2.1.24.01. NK-lysin 1nkl Sus scrofa Secreted 1 0 2.8 ± 1.5 37 ± 12 -5.4
3.1.04.05. Lactotransferrin peptide (287-303) 2md1 Bos taurus Secreted 1 0 6.0 ± 1.0 71 ± 9 -7.3
3.1.07.02. Juxtamembrane peptide (636-662) of protein gp160 2me3 Human immunodeficiency virus type 1 Endosome 1 0 6.1 ± 0.4 81 ± 7 -12.4
2.4.16.03. Potassium channel toxin gamma-KTx 1.1 1ne5 Centruroides noxius (Mexican scorpion) Secreted 1 0 3.9 ± 1.0 62 ± 2 -5.2
2.3.16.02. Translocation ATPase SecA 1tf5 Bacillus subtilis Bact. Gram-pos plas. 1 0 2.5 ± 1.1 64 ± 5 -7.0
3.1.21.02. Mastoparan-L 1d7n Vespula lewisii Secreted 1 0 6.5 ± 1.7 82 ± 16 -7.5
2.1.24.01. Saposin B (peptide 195-273), structure 1 1n69 Homo sapiens Lysosome 2 0 1.2 ± 1.0 58 ± 6 -2.4
2.2.14.01. Coagulation factor VIII 2r7e Homo sapiens Eukaryo. plasma 2 0 4.5 ± 3.0 39 ± 6 -11.5
3.1.07.05. Nonstructural protein 5a 2ajo Bovine viral diarrhea virus Endoplasm. reticulum 1 0 5.0 ± 1.0 86 ± 15 -11.8
2.1.01.01. Phospholipase A2, group X 1le6 Homo sapiens Secreted 1 0 7.4 ± 0.9 78 ± 6 -13.2
3.4.02.03. Bovicin HJ50 2m8v Streptococcus equinus Secreted 1 0 2.8 ± 1.0 71 ± 8 -4.0
2.3.10.01. Peptidoglycan biosynthesis glycosyltransferase MurG, conformation 1 1nlm Escherichia coli Bact. Gram-neg inner 1 0 4.8 ± 1.1 50 ± 7 -7.5
2.1.10.01. Glycolipid transfer protein, structure 1 1tfj Bos taurus Eukaryo. plasma 1 0 3.9 ± 1.0 90 ± 5 -8.3
2.1.29.02. Apolipoprotein A-II 2ou1 Homo sapiens Secreted 2 0 2.7 ± 1.2 87 ± 2 -17.7
2.1.60.02. Potassium channel blocking domain of matrix metalloproteinase-23 2k72 Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 2.3 77 ± 22 -4.4
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2w5q Staphylococcus aureus Bact. Gram-pos plas. 1 0 0.4 ± 3.6 82 ± 11 -2.5
2.3.06.08. Pancreatic lipase-related protein 1 1rp1 Canis lupus familiaris Secreted 1 0 6.3 ± 1.0 79 ± 4 -7.5
3.4.07.02. Compstatin 1a1p Designed proteins Undefined 1 0 3.4 ± 1.9 72 ± 18 -5.6
2.2.20.01. Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 3nsu Saccharomyces cerevisiae Eukaryo. plasma 1 0 0.8 ± 1.5 57 ± 12 -4.0
2.2.34.11. Palicourein 1r1f Palicourea condensata Secreted 1 0 4.8 ± 1.4 70 ± 19 -5.0
2.1.60.03. Cysteine-rich secretory protein 2 2cq7 Homo sapiens Secreted 1 0 0.7 ± 1.1 68 ± 5 -2.5
2.2.20.01. Rac-beta serine/threonine protein kinase 1p6s Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 83 ± 11 -5.7
2.2.06.02. Retinol-binding protein 1 5h9a Homo sapiens Eukaryo. plasma 1 0 3.3 ± 0.9 59 ± 4 -5.7
2.2.19.01. Adsorption protein p2 1n7v Bacteriophage prd1 Viral 1 0 8.7 ± 0.4 81 ± 1 -8.6
2.2.34.02. Omega-theraphotoxin-Hh1a 1y29 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 0.7 ± 1.3 83 ± 17 -2.7
2.2.34.11. Varv peptide F 3e4h Viola arvensis Secreted 1 0 4.2 ± 3.0 87 ± 43 -5.6
3.1.20.01. Alpha-conotoxin OmIA 2gcz Conus omaria (Omaria cone) Secreted 1 0 3.0 ± 1.5 62 ± 11 -3.7
2.2.23.01. Lipoprotein BamB, conformation 1 3prw Escherichia coli Bact. Gram-neg outer 1 0 5.1 ± 1.2 81 ± 7 -8.5
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase, another loop disordered 4ff6 Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 3.4 ± 1.5 19 ± 6 -6.4
3.1.21.09. Cytotoxic linear peptide IsCT 1t51 Opisthacanthus madagascariensis Secreted 1 0 4.1 ± 0.6 87 ± 11 -10.5
2.2.05.02. Mavicyanin 1ws8 Cucurbita pepo Undefined 1 0 3.7 ± 0.5 31 ± 8 -6.5
2.4.15.01. Protein Nef (HIV HV1LW) 2nef Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 6.3 ± 1.4 73 ± 3 -7.9
2.2.41.01. Beta-defensin 1 1ijv Homo sapiens Secreted 1 0 3.5 ± 1.9 74 ± 17 -5.4
2.4.16.04. Flower-specific gamma-thionin-like protein 4uj0 Solanum lycopersicum Secreted 1 0 2.6 ± 0.9 19 ± 5 -4.8
2.4.06.01. StAR-related lipid transfer protein 13 2pso Homo sapiens Eukaryo. plasma 1 0 3.1 ± 4.0 77 ± 27 -4.6
1.2.43.01. Envelope glycoprotein, West Nile virus, structure 1 2hg0 West Nile virus Viral 1 0 4.8 ± 2.6 44 ± 4 -4.3
3.1.01.02. Leader peptide of patellamide protein 2kya Prochloron didemni Secreted 1 0 5.8 ± 0.5 86 ± 4 -8.8
1.2.44.01. Amyloid beta A4 protein (peptide 672-711), in water 2lfm Homo sapiens Eukaryo. plasma 1 0 5.3 ± 0.5 87 ± 4 -8.6
3.1.25.01. Latarcin-1 (M-zodatoxin-Lt1a) 2pco Lachesana tarabaevi (Spider) Secreted 1 0 10.1 ± 0.8 77 ± 6 -9.4
2.2.34.11. Melanocortin agonist based on kalata-B1 2lur Designed proteins Undefined 1 0 6.5 ± 1.0 74 ± 21 -6.7
3.2.08.02. Major prion protein, peptide 138-143 3nve Mesocricetus auratus (Golden hamster) Eukaryo. plasma 12 0 3.6 ± 0.4 89 ± 3 -9.8
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 7 4bmm Trypanosoma cruzi Endoplasm. reticulum 1 0 8.8 ± 3.3 36 ± 30 -10.9
2.3.06.07. Lipase, open (active) state 1ex9 Pseudomonas aeruginosa Secreted 1 0 11.0 ± 1.0 52 ± 5 -30.0
3.1.20.01. O2-contryphan-Vc1 2n24 Conus victoriae (Queen Victoria cone) Secreted 1 0 1.6 ± 1.0 89 ± 22 -3.6
2.2.20.01. PH domain of muscle M-line assembly protein unc-89 1fho Caenorhabditis elegans Eukaryo. plasma 1 0 2.3 ± 1.2 25 ± 14 -4.3
1.2.01.01. Fibroblast growth factor receptor 2 complex 3oj2 Homo sapiens Secreted 6 0 2.0 ± 0.4 81 ± 3 -5.4
2.3.16.06. ADP-ribosylation factor 1 (ARF1), different conformation 2ksq Saccharomyces cerevisiae Golgi 1 0 4.7 ± 0.1 62 ± 0 -10.4
2.4.16.01. Alpha-toxin Cn12 1pe4 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.1 ± 2.3 17 ± 13 -3.1
3.1.05.03. Lavracin 2n8d Designed proteins Undefined 1 0 5.1 ± 1.2 89 ± 13 -5.7
2.4.31.01. Ficolin-1 2wnp Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.8 65 ± 2 -5.3
3.1.19.01. Antiamoebin I 1joh Emercelliopsis sp. Secreted 1 0 8.1 ± 0.8 82 ± 5 -11.7
2.1.02.01. Arachidonate 15-lipoxygenase 5ir4 Pseudomonas aeruginosa Secreted 1 0 4.9 ± 1.8 71 ± 2 -11.8
2.4.40.01. IpgB2 protein 3lxr Shigella flexneri Bact. Gram-neg inner 2 0 2.7 ± 0.4 75 ± 2 -6.7
2.3.05.04. Reticulon-4-interacting protein 1 2vn8 Homo sapiens Mitochon. inner 1 0 4.0 ± 0.0 82 ± 0 -10.2
3.1.31.01. Dermcidin, crystal structure 2ymk Homo sapiens Secreted 1 0 4.8 ± 1.3 90 ± 0 -31.0
2.4.06.05. Thermoacidophile-specific fatty acid carrier 3w9k Sulfolobus tokodaii Archaebac. 1 0 2.7 ± 1.4 47 ± 4 -7.1
1.2.49.01. Tumor necrosis factor receptor 12A 2kmz Homo sapiens Eukaryo. plasma 1 0 5.9 ± 1.6 66 ± 3 -6.3
2.4.05.01. Sterol carrier protein 2 like domain of multifunctional enzyme type 2 1ikt Homo sapiens Peroxisome 1 0 3.5 ± 1.2 75 ± 17 -4.0
3.1.29.01. Cathelicidin-6 2ket Bos taurus Secreted 1 0 7.1 ± 0.7 82 ± 3 -13.6
3.1.04.04. Peptide of huntigtin, 1-17 2ld2 Homo sapiens Eukaryo. plasma 1 0 4.2 ± 0.6 90 ± 4 -9.3
2.1.08.01. Cytochrome c6 1f1f Arthrospira maxima Thylakoid 1 0 4.8 ± 1.6 80 ± 15 -3.5
2.1.01.01. Snake phospholipase A2, group I 1s6b Naja sagittifera Secreted 1 0 3.0 ± 1.1 81 ± 10 -7.5
2.4.34.01. Type-3 ice-structuring protein HPLC 12 4ny6 Zoarces americanus Secreted 1 0 3.3 ± 0.8 58 ± 9 -5.8
2.1.01.01. Acidic phospholipase A2 5 4rfp Trimeresurus stejnegeri Secreted 1 0 2.8 ± 0.3 81 ± 3 -7.1
3.1.07.01. Fusion peptide (510-532) of protein gp41 2pjv Human immunodeficiency virus type 1 Endosome 1 0 8.7 ± 3.8 64 ± 4 -10.9
3.1.21.06. Spinigerin 1zrv Pseudacanthotermes spiniger Secreted 1 0 2.1 ± 3.4 77 ± 5 -3.9
2.1.03.01. Phospholipase C 1p6d Bacillus cereus Secreted 1 0 2.8 ± 1.0 52 ± 6 -8.4
2.2.49.02. Lytic polysaccharide monooxygenase 5tkg Neurospora crassa Secreted 1 0 7.6 ± 3.6 16 ± 19 -6.5
2.1.01.01. Snake phospholipase A2, group II, B 1jia Agkistrodon halys pallas Secreted 1 0 3.3 ± 0.5 78 ± 4 -11.2
3.2.01.01. Alvinellacin 2llr Alvinella pompejana Secreted 1 0 1.6 ± 1.4 90 ± 5 -2.6
2.1.08.01. Cytochrome c551 1cor Pseudomonas stutzeri Bact. Gram-neg inner 1 0 2.6 ± 1.1 73 ± 12 -6.1
2.2.27.01. C1 domain of protein kinase C delta 1ptr Mus musculus Eukaryo. plasma 1 0 6.6 ± 1.5 19 ± 8 -5.9
2.2.26.01. FYVE domain of Vps27 protein 1vfy Saccharomyces cerevisiae Vacuole 1 0 3.7 ± 1.8 24 ± 19 -4.2
3.1.28.01. Dermaseptin-4 2dd6 Phyllomedusa sauvagei (Sauvage's leaf frog) Secreted 1 0 4.2 ± 1.6 76 ± 6 -7.0
2.3.10.04. Teichoic acid biosynthesis protein TagF 3l7l Staphylococcus epidermidis Bact. Gram-pos plas. 1 0 6.9 ± 2.0 35 ± 15 -10.8
2.1.01.01. Phospholipase A2 BnSP-7 1pa0 Bothrops neuwiedi pauloensis Secreted 1 0 2.8 ± 1.0 78 ± 10 -6.9
2.3.06.04. Palmitoyl-protein thioesterase 1 3gro Homo sapiens Lysosome 1 0 3.6 ± 0.1 55 ± 3 -6.8
2.4.05.01. Sterol carrier protein 2-like 2 2qzt Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 1.0 ± 2.0 45 ± 12 -3.0
2.3.06.08. Pancreatic lipase 1hpl Equus caballus Secreted 1 0 3.8 ± 0.3 80 ± 5 -8.1
3.4.12.03. Bacitracin 4k7t Bacillus subtilis Secreted 1 0 9.0 ± 0.9 69 ± 8 -8.4
2.2.11.01. Synaptotagmin-4 1ugk Homo sapiens Eukaryo. plasma 1 0 2.5 ± 1.7 34 ± 11 -3.5
2.3.08.02. Cytosolic phospholipase A2 delta, structure 1 5ixc Homo sapiens Vesicle 1 0 5.5 ± 2.0 85 ± 31 -4.4
2.2.34.01. Kappa-conotoxin PVIIA 1av3 Conus purpurascens (Purple cone) Secreted 1 0 3.4 ± 1.9 77 ± 7 -3.2
2.2.27.01. RAS guanyl-releasing protein 1 4l9m Homo sapiens Eukaryo. plasma 1 0 5.3 ± 1.3 24 ± 3 -7.8
2.3.23.01. Beta-Ketoacyl synthase/Acyl transferase 1tqy Streptomyces coelicolor Bact. Gram-pos plas. 2 0 1.4 ± 0.2 83 ± 1 -4.9
2.1.01.01. Snake phospholipase A2 crotoxin basic chain 2, group II 2qog Crotalus durissus terrificus Secreted 1 0 2.1 ± 1.1 84 ± 8 -7.2
3.1.05.05. Anticoccidial peptide PW2 2jq2 Designed proteins Undefined 1 0 6.2 ± 2.3 67 ± 36 -4.5
1.2.04.01.