PDB ID or protein name

All proteins in OPM (3890 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.2.34.02. U1-theraphotoxin-Hh1a 1i25 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.6 ± 0.2 79 ± 1 -5.1
2.3.06.09. Cutinase-like protein 2czq Cryptococcus sp. Secreted 1 0 4.9 ± 1.3 54 ± 16 -9.0
2.4.16.04. Defensin-like protein 1 1ayj Raphanus sativus Secreted 1 0 11.0 ± 1.9 39 ± 19 -7.4
2.4.16.04. Defensin Lc-def 2lj7 Lens culinaris Secreted 1 0 2.2 ± 0.9 22 ± 10 -3.9
3.1.02.16. Peptide 211-263 of YscU protein 2ml9 Yersinia pseudotuberculosis Bact. Gram-neg inner 1 0 2.9 ± 1.8 82 ± 5 -6.6
2.3.18.01. Choline O-acetyltransferase 2fy2 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 2.2 87 ± 17 -5.2
2.3.18.01. Carnitine O-octanoyltransferase 1nm8 Homo sapiens Mitochon. inner 1 0 1.7 ± 3.0 67 ± 15 -5.3
3.1.07.05. Nonstructural protein 4b, segment 1716-1755 2lvg Hepatitis C virus Viral 1 0 6.4 ± 0.7 82 ± 8 -11.4
3.1.11.01. Peptide YY 1ru5 Sus scrofa Secreted 1 0 5.1 ± 1.2 83 ± 3 -5.3
2.3.16.04. Dynamin-like protein 2j69 Nostoc punctiforme Bact. Gram-neg inner 1 0 4.0 ± 7.0 15 ± 10 -5.5
2.1.18.01. Annexin VI 1m9i Homo sapiens Eukaryo. plasma 1 0 2.8 ± 0.3 82 ± 0 -8.5
1.2.60.01. Dysferlin, dysferlin domain 4cah Homo sapiens Eukaryo. plasma 1 0 5.5 ± 1.4 23 ± 5 -6.0
2.1.01.01. Phospholipase A2 homolog 1ppa Agkistridon piscivorus Secreted 1 0 1.2 ± 0.9 85 ± 8 -4.5
2.3.06.17. Group XV phospholipase A2 4x90 Homo sapiens Lysosome 1 0 1.9 ± 0.5 56 ± 1 -7.3
2.3.06.03. Gastric lipase, open (active) state 1k8q Canis lupus familiaris Secreted 1 0 7.2 ± 0.5 78 ± 6 -12.6
3.1.22.01. Antifungal peptide 2mp9 Cenchritis muricatus Secreted 1 0 1.2 ± 1.5 90 ± 26 -3.7
1.1.26.07. STAS domain of sulfate permease 4dgh Vibrio cholerae Bact. Gram-neg inner 1 0 4.6 ± 0.6 33 ± 2 -6.2
2.2.20.01. FYVE, RhoGEF and PH domain-containing protein 6 1wgq Mus musculus Eukaryo. plasma 1 0 2.5 ± 1.8 68 ± 17 -3.2
1.2.43.04. Glycoprotein G, structure 2 5i2s Vesicular stomatitis virus Viral 3 0 5.3 ± 0.4 89 ± 1 -10.4
3.2.08.01. Peptide 35-42, alternate polymorph II 2y3l Homo sapiens Secreted 4 0 2.7 ± 1.4 78 ± 8 -6.0
1.2.39.03. Disintegrin and metalloproteinase domain-containing protein 10 2ao7 Bos taurus Golgi 1 0 3.1 ± 1.4 81 ± 6 -5.7
2.4.11.01. Viscotoxin A1 3c8p Viscum album Secreted 1 0 2.3 ± 0.9 45 ± 7 -4.9
3.1.05.04. Distinctin 1xkm Designed proteins Undefined 2 0 3.9 ± 0.4 87 ± 2 -4.6
1.3.17.02. BamCD lipoprotein complex 3tgo Escherichia coli Bact. Gram-neg outer 2 0 3.7 ± 2.1 81 ± 20 -3.3
2.4.06.01. Second StARkin domain of Lam2, dimer 5yqq Saccharomyces cerevisiae Endoplasm. reticulum 2 0 5.8 ± 1.6 88 ± 5 -7.7
3.1.11.01. Neuropeptide Y-pancreatic polypeptide hybrid 1tz4 Sus scrofa Secreted 1 0 5.1 ± 1.0 88 ± 8 -6.1
2.4.16.04. Defensin-like protein 2 2n2r Raphanus sativus Secreted 1 0 2.5 ± 1.7 31 ± 24 -4.2
3.1.04.03. Viral protein R, peptide 59-86 1dsk Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 9.5 ± 0.4 65 ± 6 -11.7
1.2.33.02. Monoamine oxidase B, monomer 1s3e Homo sapiens Mitochon. outer 2 0 7.3 ± 0.6 37 ± 1 -14.2
2.4.36.01. Transforming growth factor beta-1 3rjr Sus scrofa Secreted 2 0 5.8 ± 2.0 82 ± 16 -9.5
2.4.06.04. STAR-related bacterial protein 2d4r Thermus thermophilus Bact. Gram-neg inner 1 0 6.9 ± 2.2 28 ± 6 -7.1
2.3.02.01. Phospholipase C-delta isoform 1 1djx Rattus norvegicus Eukaryo. plasma 1 0 4.1 ± 0.9 68 ± 5 -7.2
1.2.41.01. Acyl-CoA-binding domain-containing protein 4 2wh5 Homo sapiens Peroxisome 1 0 7.2 ± 2.4 77 ± 26 -5.7
2.2.34.05. Tachystatin-A2 1cix Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 3.9 ± 2.9 65 ± 14 -4.7
2.3.07.01. Endoglucanase 1vho Thermotoga maritima Undefined 1 0 5.4 ± 0.2 89 ± 1 -7.0
3.4.02.02. Mersacidin, structure in DPC micelles 1mqy Bacillus sp. Secreted 1 0 5.3 ± 0.9 90 ± 12 -6.1
1.2.39.02. Matrilysin, structure 3 2mzh Homo sapiens Secreted 1 0 2.2 ± 1.6 67 ± 22 -6.4
2.2.07.01. Lipocalin BcnB 5ixg Burkholderia cepacia Bact. Gram-neg inner 1 0 2.0 ± 1.0 36 ± 5 -3.9
3.1.03.04. Anchor helix of protein yopD (peptide 278-300) 1kdl Yersinia pseudotuberculosis Eukaryo. plasma 1 0 5.7 ± 0.8 86 ± 12 -5.0
3.2.01.07. Cyclic beta-hairpin peptide 2m7i Designed proteins Secreted 1 0 2.0 ± 0.5 84 ± 8 -4.1
2.2.20.01. PH domain of 3-phosphoinositide-dependent protein kinase 1 1w1g Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 20 ± 18 -4.8
2.2.29.01. Multivesicular body subunit 12B 3tow Homo sapiens Endosome 1 0 4.5 ± 2.3 33 ± 22 -5.8
2.2.28.01. Tachycitin 1dqc Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 4.5 ± 0.8 78 ± 8 -5.6
3.1.04.07. Peptide (70-94) of antifreeze protein Afp1 2lq1 Glaciozyma antarctica Undefined 1 0 6.2 ± 4.3 87 ± 1 -8.8
1.3.24.01. Cation efflux system protein CusC, monomer 4k7k Escherichia coli Bact. Gram-neg outer 1 0 3.2 ± 0.9 85 ± 1 -7.2
3.1.03.09. Peptide (2-11) of ADP-ribosylation factor 6, in aqueous solution 2bao Homo sapiens Eukaryo. plasma 1 0 8.0 ± 1.2 82 ± 8 -5.5
2.4.11.01. Viscotoxin B 1jmp Viscum album Secreted 1 0 1.2 ± 1.4 52 ± 13 -3.2
2.1.19.01. Nigellin 2nb2 Nigella sativa Secreted 1 0 4.7 ± 2.2 69 ± 12 -4.4
1.2.03.02. SLAM family member 6 2if7 Homo sapiens Eukaryo. plasma 3 0 2.0 ± 3.3 88 ± 11 -7.1
2.1.36.01. Endoplasmic reticulum oxidoreductin 1rp4 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.0 ± 1.8 16 ± 9 -4.7
2.1.13.01. Molt-inhibiting hormone 1j0t Marsupenaeus japonicus Secreted 1 0 4.1 ± 0.4 66 ± 6 -7.0
3.2.01.05. Cys-free protegrin analogue 2mq2 Designed proteins Secreted 1 0 1.3 ± 1.1 61 ± 19 -3.5
2.2.27.01. Beta-chimaerin 1xa6 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 1.7 65 ± 7 -5.1
2.2.33.01. Antimicrobial peptide 1b 2lb7 Triticum kiharae (Wheat) Secreted 1 0 2.2 ± 0.7 89 ± 7 -2.5
3.1.05.03. Antimicrobial peptide PaDBS1R1 2n9r Designed proteins Undefined 1 0 5.6 ± 1.0 83 ± 6 -8.3
2.3.06.09. Lysin B from mycobacteriophage 3hc7 Mycobacterium phage D29 Bact. Gram-pos plas. 1 0 6.6 ± 2.0 50 ± 12 -7.0
3.1.15.02. Plantaricin-A 1ytr Lactobacillus plantarum Secreted 1 0 9.0 ± 0.5 78 ± 10 -9.4
3.1.28.04. Esculentin-1A, structure 2 5xdj Pelophylax esculentus Secreted 1 0 7.2 ± 1.2 76 ± 8 -5.4
1.2.42.01. Glideosome-associated protein 50 3tgh Plasmodium falciparum Endoplasm. reticulum 1 0 4.2 ± 3.4 69 ± 3 -4.3
2.1.01.01. Phospholipase A2, group IB 1g4i Bos taurus Secreted 1 0 1.9 ± 0.5 87 ± 4 -7.4
3.2.05.02. Astexin-3 2m8f Asticcacaulis excentricus Secreted 1 0 6.2 ± 1.1 64 ± 28 -5.9
2.2.18.01. Subunit mu of AP-2 clatrin adaptor complex, open conformation 2xa7 Rattus norvegicus Vesicle 4 0 3.1 ± 2.2 84 ± 14 -5.9
3.1.31.01. Dermcidin, structure 1 2ksg Homo sapiens Secreted 1 0 4.7 ± 1.4 45 ± 6 -7.0
2.3.16.01. Shikimate kinase 1e6c Erwinia chrysanthemi Bact. Gram-neg inner 2 0 2.6 ± 1.8 90 ± 12 -5.8
2.1.29.01. Apolipoprotein E 1ya9 Mus musculus Secreted 1 0 1.6 ± 1.4 85 ± 11 -4.1
2.4.16.03. Potassium channel toxin alpha-KTx 6.9 6avd Opistophthalmus carinatus Secreted 1 0 1.5 ± 1.6 57 ± 7 -2.9
1.2.32.01. Cytochrome P450 2B6, conformation 3 4i91 Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 2.9 59 ± 11 -11.3
2.2.34.11. Cycloviolacin O1 1df6 Viola odorata Secreted 1 0 4.1 ± 1.2 63 ± 19 -5.9
2.1.60.03. Cysteine-rich secretory protein 2 2a05 Mus musculus Secreted 1 0 1.4 ± 1.8 52 ± 133 -2.8
2.1.02.01. Seed lipoxygenase-1 1yge Glycine max Eukaryo. plasma 1 0 3.0 ± 2.6 68 ± 3 -6.4
2.2.34.02. ACTX-HI:OB4219 1kqi Hadronyche infensa Secreted 1 0 5.2 ± 1.2 72 ± 15 -8.2
3.1.21.02. Anoplin 2mjq Anoplius samariensis Secreted 1 0 5.6 ± 1.1 85 ± 8 -8.4
2.2.11.01. Extended synaptotagmin-2, third C2 domain 2dmg Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.0 76 ± 5 -4.8
3.1.07.01. Fusion peptide (524-539) of ebolavirus glycoprotein GP2 2rlj Zaire ebolavirus Viral 1 0 5.8 ± 1.8 84 ± 6 -6.8
3.2.02.02. Chi-conotoxin MrIB 1ieo Conus marmoreus Secreted 1 0 2.2 ± 1.1 45 ± 12 -1.9
2.1.15.01. Epsin-1 1h0a Rattus norvegicus Eukaryo. plasma 1 0 3.2 ± 1.1 39 ± 19 -5.3
2.3.02.04. Phosphatidylinositol-specific phospholipase C1 3h4x Streptomyces antibioticus Bact. Gram-pos plas. 1 0 3.7 ± 0.4 63 ± 2 -7.3
3.1.18.01. Delta-hemolysin 1dtc Staphylococcus aureus Secreted 1 0 3.2 ± 2.2 87 ± 19 -8.5
2.2.39.01. Toxin B 1txa Ophiophagus hannah Secreted 1 0 2.6 ± 1.5 51 ± 16 -5.6
2.2.32.01. ADP-ribosylating toxin CARDS, nicked 4tlv Mycoplasma pneumoniae Secreted 1 0 3.7 ± 1.1 44 ± 10 -4.8
2.3.06.01. Neuroligin-4, X-linked, complex with neurexin 1-beta 2xb6 Homo sapiens Eukaryo. plasma 2 0 1.9 ± 3.0 84 ± 11 -3.3
2.3.05.04. Reticulon-4-interacting protein 1 2vn8 Homo sapiens Mitochon. inner 1 0 4.0 ± 0.0 82 ± 0 -10.2
3.2.06.01. Growth-blocking peptide, long form 2eqt Pseudaletia separata (Oriental armyworm) Secreted 1 0 4.1 ± 1.4 59 ± 8 -5.7
2.1.20.01. Prothrombin 1nl2 Bos taurus Eukaryo. plasma 1 0 3.9 ± 3.0 18 ± 24 -5.8
2.2.12.01. Lymphocyte antigen 96, structure 1 2e56 Homo sapiens Secreted 1 0 3.6 ± 0.7 68 ± 4 -6.7
2.2.11.01. Protein kinase C beta 3pfq Rattus norvegicus Eukaryo. plasma 1 0 2.6 ± 0.9 45 ± 5 -3.4
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 5frb Aspergillus fumigatus Endoplasm. reticulum 1 0 11.8 ± 0.5 59 ± 1 -13.2
2.3.06.07. Lipase 1qge Pseudomonas glumae Secreted 1 0 3.7 ± 0.9 24 ± 3 -7.7
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3a 5ebe Homo sapiens Secreted 1 0 2.6 ± 0.6 38 ± 1 -7.0
1.2.03.02. Hepatitis A virus cellular receptor 2 homolog 3kaa Mus musculus Eukaryo. plasma 1 0 2.8 ± 2.0 55 ± 16 -5.5
1.2.61.01. Mitochondrial inner membrane translocase subunit TIM50 4qqf Saccharomyces cerevisiae Mitochon. inner 1 0 5.4 ± 0.8 76 ± 1 -7.0
1.2.43.01. Envelope glycoprotein, Zika virus, structure 6 5gzn Zika virus Viral 1 0 5.1 ± 2.6 41 ± 11 -4.9
2.2.45.02. Pectate lyase A 1pe9 Erwinia chrysanthemi Secreted 1 0 2.7 ± 0.4 81 ± 3 -6.4
2.2.20.01. PH domain of GPCR kinase 2 2bcj Bos taurus Eukaryo. plasma 3 0 5.7 ± 1.5 85 ± 5 -10.4
2.1.64.01. Envelope glycoprotein, ligand-binding domain 2 5fb7 Talaromyces marneffei Eukaryo. plasma 1 0 3.2 ± 2.5 64 ± 10 -2.9
2.4.25.01. N-alpha-acetyltransferase 60, structure 2 5hh0 Homo sapiens Golgi 1 0 5.2 ± 0.0 46 ± 1 -10.7
2.4.16.01. Alpha-like toxin CsEv5 1i6f Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.4 ± 1.3 59 ± 4 -5.8
3.1.06.02. Class A amphipathic helical peptide 2fq5 Designed proteins Undefined 1 0 6.5 ± 1.4 78 ± 6 -8.8
1.2.17.01. SNARE complex with synaptotagmin1 2n1t Rattus norvegicus Eukaryo. plasma 5 0 2.6 ± 2.9 42 ± 16 -4.6
3.1.19.01. Cephaibol B 1ob6 Acremonium tubakii Secreted 1 0 15.0 ± 5.0 42 ± 17 -15.3
1.3.25.01. LukGH complex 5k59 Staphylococcus aureus Secreted 2 0 4.7 ± 2.8 41 ± 15 -5.4
1.1.56.01. Inner membrane protein YejM, strain K12 5i5h Salmonella typhimurium Bact. Gram-neg inner 1 0 1.1 ± 1.6 65 ± 2 -3.6
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase SMURF1 3pyc Homo sapiens Eukaryo. plasma 1 0 4.5 ± 2.1 23 ± 17 -5.7
2.1.04.01. Prostaglandin H2 synthase-1 1q4g Ovis aries Endoplasm. reticulum 2 0 8.9 ± 0.4 90 ± 1 -43.4
3.1.19.01. Samarosporin I 4g13 Samarospora rostrup Secreted 1 0 16.7 ± 1.5 64 ± 14 -15.3
2.2.25.01. Superoxide dismutase [Cu-Zn] 1oal Photobacterium leiognathi Bact. Gram-neg inner 1 0 2.4 ± 0.9 77 ± 2 -6.8
2.4.06.01. Cholesterol-regulated Start protein 4 (StarD4) 5brl Mus musculus Eukaryo. plasma 1 0 3.7 ± 1.1 67 ± 13 -3.7
2.4.07.01. PX domain of sorting nexin GRD19, ligand-free 1ocs Saccharomyces cerevisiae Endosome 1 0 2.5 ± 1.1 88 ± 11 -5.4
3.1.29.01. Cathelicidin-3, peptide 121-151 2hfr Gallus gallus Secreted 1 0 3.1 ± 4.2 86 ± 1 -8.0
2.4.25.01. Uncharacterized N-acetyltransferase SSO0209 2x7b Sulfolobus solfataricus Undefined 1 0 3.9 ± 1.5 49 ± 6 -7.6
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 3 4axc Arabidopsis thaliana Eukaryo. plasma 1 0 3.2 ± 2.3 68 ± 15 -4.5
2.1.01.01. Snake phospholipase A2 isoform 5, group I 1y75 Naja sagittifera Secreted 1 0 4.4 ± 0.7 81 ± 10 -5.7
2.3.04.01. Pteridine reductase 1 1p33 Leishmania tarentolae (Sauroleishmania tarentolae) Eukaryo. plasma 4 0 3.4 ± 1.0 73 ± 13 -7.7
3.1.07.05. Nonstructural protein 5a 2ajo Bovine viral diarrhea virus Endoplasm. reticulum 1 0 5.0 ± 1.0 86 ± 15 -11.8
2.1.29.01. Apolipoprotein A-I 2lem Mus musculus Secreted 1 0 2.7 ± 1.7 79 ± 2 -4.3
2.1.15.03. Clathrin assembly lymphoid myeloid leukemia (CALM) protein 1hfa Rattus norvegicus Eukaryo. plasma 1 0 14.2 ± 2.0 44 ± 14 -17.9
3.1.25.01. Latarcin-2a (M-zodatoxin-Lt2a) 2g9p Lachesana tarabaevi (Spider) Secreted 1 0 8.5 ± 1.4 77 ± 9 -6.4
2.2.16.01. Lipoprotein lppX 2byo Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 1.9 ± 1.7 80 ± 13 -4.8
2.4.04.01. Sphingomyelinase C 2ddt Bacillus cereus Secreted 1 0 4.1 ± 1.1 59 ± 8 -7.6
3.2.01.05. Protegrin-5 2nc7 Sus scrofa Secreted 1 0 2.3 ± 1.2 87 ± 6 -2.4
1.2.36.01. Hemagglutinin-neuraminidase glycoprotein 1v3e Human parainfluenza virus 3 Eukaryo. plasma 2 0 1.9 ± 0.4 81 ± 34 -6.5
2.1.01.01. Snake phospholipase A2, group II 1pp2 Crotalus atrox Secreted 1 0 3.7 ± 1.3 80 ± 7 -12.9
3.1.11.05. Parathyroid hormone 1et1 Homo sapiens Secreted 1 0 2.1 ± 0.5 85 ± 3 -5.6
2.2.20.01. Spectrin beta chain 1btn Mus musculus Eukaryo. plasma 1 0 13.7 ± 1.6 57 ± 19 -17.3
3.1.03.02. Serine/threonine-protein kinase TOR1, FATC domain 2kit Saccharomyces cerevisiae Vacuole 1 0 6.3 ± 1.0 87 ± 18 -6.4
3.1.30.01. Lactoferrin-based peptide, 39-49 2gmc Homo sapiens Secreted 1 0 3.9 ± 1.7 79 ± 13 -4.6
3.2.10.02. PLP-2 peptide 6axi Designed proteins Undefined 1 0 7.2 ± 7.2 28 ± 12 -7.0
1.2.03.08. HLA class II histocompatibility antigen, DM alpha chain 2bc4 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 0.7 21 ± 3 -4.7
2.1.30.01. Membrane-integrating protein mistic, mstX 1ygm Bacillus subtilis Bact. Gram-pos plas. 1 0 2.6 ± 1.8 31 ± 6 -5.2
2.2.34.02. Jingzhaotoxin-11 2a2v Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.0 ± 1.8 74 ± 19 -4.6
2.2.34.02. Mu-hexatoxin-Mg2a 6ax2 Macrothele gigas (Spider) Secreted 1 0 5.4 ± 1.6 88 ± 30 -7.9
2.2.06.01. Complement component C8 gamma chain 1lf7 Homo sapiens Secreted 1 0 1.9 ± 2.2 43 ± 12 -2.6
3.4.12.02. Thiostrepton, epimer form 2l2y Streptomyces azureus Secreted 1 0 2.7 ± 2.9 29 ± 9 -5.3
2.2.04.01. Retinoid isomerohydrolase, conformation 1 3fsn Bos taurus Eukaryo. plasma 1 0 7.8 ± 1.0 73 ± 10 -10.3
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 4 5o9o Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.9 ± 1.6 88 ± 2 -6.3
2.2.11.01. Synaptotagmin-7 3n5a Mus musculus Vesicle 1 0 2.2 ± 2.3 30 ± 12 -4.1
2.2.34.08. Agouti-signaling protein 1y7j Homo sapiens Secreted 1 0 3.8 ± 1.6 62 ± 7 -6.9
2.3.05.02. Sulfide-quinone reductase 3sx6 Acidithiobacillus ferrooxidans Bact. Gram-neg inner 1 0 10.6 ± 0.6 70 ± 8 -7.3
1.2.03.02. Hepatitis A virus cellular receptor 2 5f71 Homo sapiens Eukaryo. plasma 1 0 4.0 ± 2.0 63 ± 7 -5.3
2.1.01.01. Snake phospholipase A2, ammodytoxin A, group II 3g8g Vipera ammodytes ammodytes Secreted 1 0 4.1 ± 0.9 80 ± 6 -11.0
3.4.12.04. Motuporin 1evd Theonella swinhoei Secreted 1 0 16.5 ± 2.8 23 ± 24 -8.8
2.4.16.14. U3-scytotoxin-Sth1a 5fzv Scytodes thoracica Secreted 1 0 4.3 ± 3.2 76 ± 4 -7.2
3.1.07.06. NS2 protease, segment 766-789 of polyprotein 2lzq Hepatitis GB virus Endoplasm. reticulum 1 0 3.2 ± 2.1 88 ± 1 -5.9
2.4.16.01. Beta-mammal toxin Cn2 2yc1 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.8 ± 1.1 68 ± 9 -3.8
2.3.15.01. Electron transfer flavoprotein 1efv Homo sapiens Mitochon. inner 2 0 4.6 ± 1.3 79 ± 12 -4.6
3.1.20.01. Alpha-conotoxin GID 1mtq Conus geographus (Geography cone) Secreted 1 0 1.3 ± 2.5 78 ± 28 -2.4
3.2.01.03. Thanatin 8tfv Podisus maculiventris Secreted 1 0 3.7 ± 1.0 81 ± 4 -5.3
2.3.01.01. Glucosylceramidase 2vt0 Pan troglodytes Lysosome 1 0 2.3 ± 1.0 86 ± 5 -7.3
2.2.41.02. Sea anemone toxin IA 1atx Anemonia sulcata Secreted 1 0 4.5 ± 1.7 63 ± 12 -6.1
2.3.06.16. Putative epoxide hydrolase 5bov Klebsiella pneumoniae Secreted 1 0 5.7 ± 1.4 23 ± 10 -5.1
1.2.43.01. Envelope glycoprotein, Dengue virus type 3 1uzg Dengue virus Viral 1 0 5.7 ± 2.7 18 ± 7 -5.4
2.3.01.03. Alpha-amylase A 1wza Halothermothrix orenii Secreted 1 0 1.6 ± 0.4 80 ± 1 -6.7
2.2.14.01. C2 domain of coagulation factor VIII 1d7p Homo sapiens Eukaryo. plasma 1 0 4.8 ± 2.0 28 ± 10 -8.8
2.4.07.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Homo sapiens Golgi 1 0 2.5 ± 1.3 56 ± 16 -4.8
1.2.50.01. Fragaceatoxin C, monomer 3lim Actinia fragacea (Strawberry anemone) Secreted 1 0 2.6 ± 0.8 46 ± 15 -5.0
2.2.34.11. Kalata B1, all-D analogue 2jue Designed proteins Undefined 1 0 3.7 ± 1.0 82 ± 17 -5.5
2.2.20.01. Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 4a6f Saccharomyces cerevisiae Eukaryo. plasma 1 0 1.9 ± 1.6 62 ± 4 -6.1
1.2.32.01. Cytochrome P450 17A1 6b82 Danio rerio Endoplasm. reticulum 1 0 6.3 ± 1.6 48 ± 1 -23.3
2.4.11.01. beta-Purothionin 1bhp Triticum aestivum Secreted 1 0 2.9 ± 2.0 56 ± 19 -4.8
2.3.06.19. PHB depolymerase PhaZ7, structure 2 4btv Pseudomonas lemoignei Secreted 1 0 1.0 ± 2.3 64 ± 35 -5.2
1.2.54.01. Dihydroorotate dehydrogenase, 32-65 peptide 5tce Homo sapiens Mitochon. inner 1 0 3.7 ± 1.2 84 ± 7 -7.4
2.3.33.01. Endo-beta-N-acetylglucosaminidase 2vtf Arthrobacter protophormiae Secreted 1 0 4.1 ± 0.7 52 ± 2 -6.5
2.2.06.02. Cellular retinoic acid-binding protein 1 1cbr Bos taurus Eukaryo. plasma 1 0 6.5 ± 1.1 45 ± 11 -5.4
2.2.09.04. Nucleoporin NUP120 3f7f Saccharomyces cerevisiae Nuclear inner 1 0 9.3 ± 2.1 66 ± 5 -11.0
2.2.41.01. Defensin-like peptide 2/4 1d6b Ornithorhynchus anatinus Secreted 1 0 9.2 ± 0.7 73 ± 2 -11.0
2.3.24.01. Phosphatase YidA 1rkq Escherichia coli Undefined 1 0 2.5 ± 1.3 79 ± 9 -4.1
3.2.05.02. Microcin J25, peptide 38-58, cleaved after 47 1s7p Escherichia coli Secreted 1 0 4.7 ± 1.2 83 ± 18 -5.7
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3a 5fc1 Mus musculus Secreted 1 0 2.3 ± 3.0 62 ± 17 -4.8
2.4.15.01. Protein Nef, complex with tyrosine-protein kinase SH3 domain (HIV HV1A2) 3rbb Human immunodeficiency virus type 1 Eukaryo. plasma 2 0 2.4 ± 1.1 84 ± 6 -4.2
2.4.42.01. Latherin 3zpm Equus caballus Secreted 1 0 6.0 ± 0.4 75 ± 1 -8.0
2.2.12.02. Rho GDP-dissociation inhibitor 1 1qvy Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.7 53 ± 19 -5.1
3.1.07.01. Fusion peptide (512-541) of protein gp41 2ari Human immunodeficiency virus type 1 Endosome 1 0 10.0 ± 1.0 88 ± 9 -16.1
3.1.15.01. Carnobacteriocin B2 1cw5 Carnobacterium maltaromaticum Secreted 1 0 6.5 ± 0.3 89 ± 5 -9.9
2.4.06.04. STAR-related bacterial protein 1t17 Caulobacter crescentus Undefined 1 0 3.4 ± 0.7 63 ± 2 -8.1
2.2.06.02. Intestinal fatty acid binding protein, structure 3 2mji Homo sapiens Eukaryo. plasma 1 0 3.3 ± 1.0 57 ± 14 -4.1
3.4.04.01. Daptomycin, Ca-free 1xt7 Streptomyces roseosporus Secreted 1 0 9.3 ± 3.9 10 ± 45 -6.4
2.2.34.02. beta-TRTX-Pre1a toxin 5i1x Psalmopoeus cambridgei (Trinidad chevron tarantula) Secreted 1 0 5.0 ± 1.6 52 ± 12 -6.3
2.4.33.01. 72 kDa type IV collagenase, full-length 1ck7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 73 ± 9 -4.0
3.1.28.06. Magainin 2 2mag Xenopus laevis Secreted 1 0 10.1 ± 0.9 81 ± 14 -13.7
2.2.35.01. Listeriolysin O 4cdb Listeria monocytogenes Secreted 1 0 3.2 ± 0.0 30 ± 0 -6.0
2.2.20.01. Son of sevenless homolog 1 (SOS-1) 1xd4 Homo sapiens Eukaryo. plasma 1 0 1.9 ± 3.0 79 ± 2 -4.5
3.1.10.01. Competence-stimulating peptide type 1 2a1c Streptococcus pneumoniae Secreted 1 0 4.8 ± 0.9 85 ± 20 -7.7
3.1.28.06. Magainin analogue 1 5cgn Designed proteins Undefined 2 0 6.1 ± 2.7 88 ± 6 -14.0
2.1.34.01. Septium site-determining protein DivIVA 2wuj Bacillus subtilis Bact. Gram-pos plas. 2 0 4.0 ± 1.8 2 ± 18 -5.4
2.3.06.06. Lipase LipA 2qua Serratia marcescens Secreted 1 0 8.9 ± 0.2 59 ± 0 -37.5
3.1.28.09. Pseudin-2, structure 2 2ncx Pseudis paradoxa Secreted 1 0 4.4 ± 4.4 85 ± 13 -9.2
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 2 2w62 Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.7 ± 0.5 90 ± 1 -6.1
2.2.02.02. Hepatitis C virus NS3 protease 2o8m Hepatitis C virus Endoplasm. reticulum 4 0 5.0 ± 1.3 72 ± 8 -9.0
2.1.01.01. Snake phospholipase A2, group I, KPA2 1g2x Bungarus caeruleus Secreted 1 0 3.8 ± 1.5 84 ± 10 -5.4
2.2.34.02. Beta-theraphotoxin-Tp1a 2m9l Thrixopelma pruriens Secreted 1 0 5.4 ± 0.7 73 ± 3 -6.6
3.1.33.01. Stage V sporulation protein M 2mvh Bacillus subtilis Vacuole 1 0 6.3 ± 1.0 90 ± 4 -9.9
2.2.34.02. Omega-theraphotoxin-Gr1a 1koz Grammostola rosea (Chilean rose tarantula) Secreted 1 0 3.6 ± 0.8 68 ± 6 -6.5
3.2.04.01. Cyclic trypsin inhibitor STFI-1 (from D-residues) 4ttk Designed proteins Undefined 1 0 6.2 ± 3.4 76 ± 15 -5.2
2.2.05.01. Azurin I 1rkr Alcaligenes xylosoxidans Bact. Gram-neg inner 1 0 1.0 ± 1.0 43 ± 7 -4.3
2.3.26.01. Phosphate acyltransferase 1u7n Enterococcus faecalis Bact. Gram-pos plas. 2 0 6.1 ± 1.5 78 ± 13 -6.1
3.1.29.03. Tritrpticin 1d6x Sus scrofa Secreted 1 0 9.4 ± 2.6 81 ± 38 -8.1
3.1.29.01. Cathelicidin LL-37, crystal structure, monomer 5nmn Homo sapiens Secreted 1 0 4.7 ± 4.7 83 ± 9 -13.6
2.2.06.01. Retinol binding protein 4 1aqb Sus scrofa Secreted 1 0 4.1 ± 1.1 75 ± 14 -4.4
1.3.25.01. Gamma-hemolysin prepore, hetero-octamer (A+B) 4p1y Staphylococcus aureus Secreted 8 0 1.3 ± 1.0 85 ± 2 -7.8
2.2.11.01. Synaptotagmin 1, C2B domain 5vfg Mus musculus Vesicle 1 0 1.6 ± 2.0 38 ± 11 -3.6
2.2.34.01. Conotoxin Gm9 1ixt Conus gloriamaris (Glory-of-the-Seas cone) Secreted 1 0 1.7 ± 1.7 85 ± 17 -3.0
2.2.11.01. C2 domain of abscisic acid-related protein CAR4 5a52 Arabidopsis thaliana Eukaryo. plasma 2 0 3.9 ± 0.7 82 ± 11 -6.6
2.2.34.02. U1-theraphotoxin-Ba1b 2kgh Brachypelma ruhnaui (Mexican golden redrump tarantula) Secreted 1 0 1.9 ± 2.5 83 ± 25 -1.9
2.2.34.11. Circulin B 2eri Chassalia parviflora Secreted 1 0 5.0 ± 1.0 69 ± 20 -8.4
3.1.29.01. EFK17A peptide derived from cathelicidin LL-37 5xng Homo sapiens Secreted 1 0 4.3 ± 1.2 88 ± 3 -10.0
2.2.06.01. Outer membrane lipoprotein Blc 1qwd Escherichia coli Bact. Gram-neg outer 1 0 3.2 ± 2.0 80 ± 15 -4.6
1.2.32.01. Cytochrome P450 17A1 4r1z Danio rerio Endoplasm. reticulum 1 0 5.0 ± 1.2 83 ± 2 -6.5
2.4.16.04. Defensin 1 1jkz Pisum sativum Secreted 1 0 3.5 ± 1.6 8 ± 19 -5.4
2.4.16.08. Theromacin 2ln8 Hirudo medicinalis Secreted 1 0 3.7 ± 0.2 72 ± 3 -6.4
2.3.18.01. Choline O-acetyltransferase 1q6x Rattus norvegicus Eukaryo. plasma 1 0 3.6 ± 0.6 75 ± 6 -8.5
2.3.18.01. Carnitine O-acetyltransferase, complex with substrate 2h3u Mus musculus Mitochon. inner 1 0 3.0 ± 1.0 87 ± 3 -5.9
3.1.07.02. Membrane proximal external helix of HIV-1 gp41 (656-683) 2m8o Human immunodeficiency virus type 1 Viral 1 0 6.0 ± 5.2 90 ± 4 -5.0
3.1.11.01. Pancreatic hormone 1ppt Meleagris gallopavo Secreted 1 0 3.5 ± 2.9 90 ± 27 -3.9
2.1.18.01. Annexin VIII 1w3w Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.0 79 ± 9 -6.2
2.1.01.01. Phospholipase A2 isoform 4 1yxh Naja sagittifera Secreted 1 0 1.7 ± 0.5 81 ± 2 -5.2
2.3.06.10. Lipase 1jfr Streptomyces exfoliatus Secreted 1 0 5.0 ± 1.3 60 ± 10 -6.4
3.2.01.08. RCB-1 peptide 2mtm Ricinus communis Secreted 1 0 10.1 ± 3.0 37 ± 37 -8.4
1.1.26.07. STAS domain of sulfate permease 4dgf Wolinella succinogenes Bact. Gram-neg inner 1 0 2.6 ± 0.5 51 ± 2 -7.0
2.2.20.01. Pleckstrin homology domain-containing family A member 6 (PLEKHA6) 2d9y Homo sapiens Eukaryo. plasma 1 0 1.0 ± 0.3 67 ± 1 -6.2
1.2.43.06. Outer capsid protein VP4, dimer 2b4h Rotavirus A Viral 2 0 2.2 ± 0.2 4 ± 1 -8.3
3.2.08.01. Peptide KLVFFA from amyloid beta, alternate polymorph II 3ow9 Homo sapiens Secreted 12 0 4.1 ± 1.4 88 ± 7 -12.8
3.1.03.03. Membrane-bound helix of phosphotransferase IIA component 1o53 Escherichia coli Bact. Gram-neg inner 1 0 3.3 ± 1.3 86 ± 15 -7.8
2.2.20.01. Dynamin-1 1dyn Homo sapiens Eukaryo. plasma 2 0 4.1 ± 1.2 88 ± 15 -9.7
2.3.05.06. Endothelin-converting enzyme 2 2pxx Homo sapiens Golgi 1 0 7.1 ± 1.3 37 ± 8 -8.4
2.4.16.01. Neurotoxin BmK-M10 2kbk Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 1.7 ± 1.0 73 ± 14 -2.4
3.1.28.05. Aurein 1.2 analogue 2f3a Designed proteins Undefined 1 0 3.0 ± 1.6 88 ± 24 -11.7
1.1.59.01. Membrane protease specific for a stomatin homolog, monomer 3bpp Pyrococcus horikoshii Archaebac. 1 0 4.0 ± 0.4 82 ± 5 -6.3
2.4.06.01. First StARkin domain of Lam4 5yqj Saccharomyces cerevisiae Endoplasm. reticulum 1 0 9.3 ± 1.4 26 ± 8 -5.2
3.1.11.02. Glucagon 1gcn Sus scrofa Secreted 1 0 5.3 ± 1.0 78 ± 12 -6.6
2.2.34.07. Asteropsin F 2n2g Asteropus sp. Secreted 1 0 4.3 ± 1.7 60 ± 11 -3.4
3.1.04.03. Viral protein R, peptide 13-33, different strain 1fi0 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 2.7 ± 1.2 88 ± 8 -8.6
2.1.24.01. Saposin-like protein Na-SLP-1 3s63 Necator americanus Secreted 1 0 2.2 ± 1.6 74 ± 10 -3.5
2.3.04.01. Sorbitol dehydrogenase 1k2w Rhodobacter sphaeroides Bact. Gram-neg inner 2 0 2.2 ± 0.3 89 ± 1 -4.4
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 405-424 1btq Homo sapiens Eukaryo. plasma 1 0 13.6 ± 2.1 67 ± 11 -22.5
1.2.41.01. Acyl-CoA-binding domain-containing protein 5 3flv Homo sapiens Peroxisome 1 0 4.6 ± 2.8 28 ± 3 -4.9
2.2.41.02. Toxin CgNa 2h9x Condylactis gigantea (Giant Caribbean anemone) Secreted 1 0 3.6 ± 1.6 70 ± 15 -2.7
2.4.27.01. Gamma-glutamylaminecyclotransferase 1vkb Mus musculus Undefined 1 0 2.3 ± 0.7 72 ± 4 -4.8
2.2.50.01. Lipoprotein TP0453, open conformation 3k8i Treponema pallidum Bact. Gram-neg outer 1 0 8.9 ± 2.4 38 ± 2 -12.0
3.4.02.02. Mersacidin, structure of lipid II bound peptide in DPC micelles 1mqz Bacillus sp. Secreted 1 0 4.2 ± 2.8 83 ± 15 -4.2
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3b 5kar Mus musculus Secreted 1 0 0.8 ± 1.3 51 ± 4 -3.9
2.2.07.01. Lipocalin BcnA 5ixh Burkholderia cepacia Bact. Gram-neg inner 1 0 1.4 ± 2.6 28 ± 29 -1.7
3.1.04.03. Viral protein R, peptide 34-51 1kzt Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.4 ± 0.6 77 ± 7 -10.3
1.2.32.01. Cholesterol 7-alpha-monooxygenase (P450 7A1), different conformation 3sn5 Homo sapiens Endoplasm. reticulum 1 0 6.0 ± 1.9 73 ± 4 -6.5
2.3.06.02. Antigen 85b 1f0n Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 3.7 ± 0.9 33 ± 7 -7.4
3.1.14.01. Neuropeptide gamma 2mce Oryctolagus cuniculus Secreted 1 0 8.4 ± 1.4 60 ± 10 -6.1
2.2.20.01. PH domain of TAPP2 1v5p Mus musculus Eukaryo. plasma 1 0 1.4 ± 1.3 61 ± 5 -3.7
2.3.16.07. Ras-related protein Rab-7a 1vg8 Rattus norvegicus Endosome 1 0 1.7 ± 0.5 74 ± 3 -5.3
2.2.28.02. Scarabaecin 1iyc Oryctes rhinoceros (Coconut rhinoceros beetle) Secreted 1 0 3.7 ± 2.3 90 ± 23 -5.0
3.1.04.07. Peptide (119-148) of antifreeze protein Afp1 2lq2 Glaciozyma antarctica Undefined 1 0 1.7 ± 2.4 84 ± 6 -8.6
2.2.23.01. Lipoprotein BamB, conformation 3 3q7o Escherichia coli Bact. Gram-neg outer 1 0 4.9 ± 1.5 69 ± 3 -6.9
2.4.11.01. Viscotoxin A2 1jmn Viscum album Secreted 1 0 2.3 ± 0.3 63 ± 8 -3.3
2.3.06.05. Esterase 5dwd Pelagibacterium halotolerans Secreted 1 0 3.1 ± 2.1 66 ± 20 -4.7
2.1.58.01. Serine/threonine-protein kinase pelle 1ik7 Drosophila melanogaster Eukaryo. plasma 1 0 1.5 ± 3.7 86 ± 0 -6.8
2.1.36.01. Endoplasmic reticulum oxidoreductin, a mutant 3m31 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.9 ± 1.2 27 ± 9 -6.2
2.1.24.01. Saposin-like protein 5 2jsa Caenorhabditis elegans Secreted 1 0 1.8 ± 2.2 47 ± 0 -3.7
3.1.04.05. Lactotransferrin peptide (287-303) 2md1 Bos taurus Secreted 1 0 6.0 ± 1.0 71 ± 9 -7.3
2.2.27.01. C1 domain of unc-13 homolog A 1y8f Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 1.9 16 ± 17 -2.9
3.1.07.01. TK9 peptide of spike glycoprotein (55-63) 5xes Human SARS coronavirus Endosome 1 0 6.7 ± 1.2 22 ± 10 -5.7
2.1.31.01. Colicin M, alternative orientation 2xmx Escherichia coli Secreted 1 0 2.4 ± 2.3 82 ± 4 -4.8
3.2.10.01. PawS derived peptide 22 2ndl Designed proteins Undefined 1 0 8.6 ± 2.1 64 ± 9 -5.3
2.3.19.01. Alpha-toxin 2vk9 Clostridium novyi Secreted 1 0 3.2 ± 1.0 80 ± 2 -5.2
3.1.26.01. Piscidin 4 5h2s Oreochromis niloticus Secreted 1 0 4.6 ± 3.2 75 ± 2 -5.8
2.1.01.01. Phospholipase A2, group IB 4p2p Sus scrofa Secreted 1 0 3.3 ± 0.8 89 ± 7 -8.6
3.4.02.03. Bovicin HJ50 2m8v Streptococcus equinus Secreted 1 0 2.8 ± 1.0 71 ± 8 -4.0
2.4.10.01. Synapsin I 1auv Bos taurus Vesicle 1 0 1.9 ± 1.1 86 ± 11 -5.2
2.1.29.05. Apolipoprotein C-III 2jq3 Homo sapiens Secreted 1 0 2.9 ± 1.4 85 ± 0 -5.6
2.3.16.01. Shikimate kinase 1via Campylobacter jejuni Bact. Gram-neg inner 2 0 3.9 ± 1.4 89 ± 11 -5.0
2.1.63.01. Lipid A biosynthesis lauroyl acyltransferase 5kn7 Acinetobacter baumannii Bact. Gram-neg outer 1 0 7.4 ± 1.4 66 ± 0 -7.5
2.3.06.08. Pancreatic lipase-related protein 2 2oxe Homo sapiens Secreted 1 0 10.2 ± 1.1 88 ± 8 -10.1
2.2.06.01. Retinol binding protein 4, structure 2 2wr6 Homo sapiens Secreted 1 0 3.7 ± 0.8 74 ± 4 -4.2
2.2.04.01. Retinoid isomerohydrolase, conformation 2 4f2z Bos taurus Eukaryo. plasma 1 0 3.7 ± 0.9 56 ± 2 -9.2
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 1 4b2z Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.3 ± 1.3 86 ± 6 -4.6
2.2.34.11. Cycloviolacin O1 1vb8 Viola hederacea Secreted 1 0 6.9 ± 1.0 88 ± 17 -9.7
2.1.60.03. Cysteine-rich secretory protein 2 2cq7 Homo sapiens Secreted 1 0 0.7 ± 1.1 68 ± 5 -2.5
2.1.02.01. Seed lipoxygenase-3 1rrh Glycine max Eukaryo. plasma 1 0 3.8 ± 1.3 84 ± 7 -5.6
2.2.34.02. Atracotoxin-hvI 1vtx Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 8.3 ± 1.0 89 ± 10 -9.4
2.3.02.03. Phospholipase D 3rlh Loxosceles intermedia Secreted 1 0 3.0 ± 0.7 81 ± 6 -6.2
2.2.11.01. Multiple C2 and transmembrane domain-containing protein 2 (MCTP2) 2ep6 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.5 7 ± 15 -3.0
3.1.07.03. Hemagglutinin, fusion peptide 346-365, G13A 2l4g Influenza virus Viral 1 0 11.1 ± 0.4 73 ± 4 -10.4
3.1.20.01. Rho-conotoxin TIA 1ien Conus tulipa (Fish-hunting cone snail) Secreted 1 0 3.4 ± 1.6 73 ± 7 -3.5
2.2.11.01. Cytosolic phospholipase A2, group IVA 1rlw Homo sapiens Eukaryo. plasma 1 0 6.4 ± 1.9 57 ± 17 -7.8
3.1.29.01. Antimicrobial protein CAP18, segment 135-166 1lyp Oryctolagus cuniculus Secreted 1 0 7.4 ± 1.0 87 ± 9 -15.6
2.1.24.01. Saposin B (peptide 195-273), structure 1 1n69 Homo sapiens Lysosome 2 0 1.2 ± 1.0 58 ± 6 -2.4
2.2.39.02. Dendroaspin (mambin) 1drs Dendroaspis jamesoni kaimosae Secreted 1 0 3.3 ± 1.5 87 ± 12 -6.5
2.4.16.04. Flower-specific gamma-thionin-like protein 4uj0 Solanum lycopersicum Secreted 1 0 2.6 ± 0.9 19 ± 5 -4.8
2.3.06.05. Acyl-protein thioesterase 1 1fj2 Homo sapiens Eukaryo. plasma 1 0 9.6 ± 2.0 64 ± 14 -4.7
2.3.15.02. FAD synthase 2wsi Saccharomyces cerevisiae Mitochon. inner 1 0 3.3 ± 1.7 65 ± 17 -4.0
3.1.12.01. Sarafotoxin-I3 2lde Atractaspis microlepidota microlepidota Secreted 1 0 4.2 ± 3.6 86 ± 8 -2.8
2.1.20.01. Coagulation factor IX 1pfx Sus scrofa Eukaryo. plasma 2 0 1.9 ± 6.0 84 ± 10 -3.9
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 1 1zhx Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.9 90 ± 7 -5.0
3.1.14.01. Scyliorhinin-1 2nou Scyliorhinus canicula (Small-spotted catshark) Secreted 1 0 8.6 ± 1.4 81 ± 10 -9.1
2.2.27.01. Ras association domain-containing protein 5, C1 domain 1rfh Mus musculus Eukaryo. plasma 1 0 1.4 ± 0.9 16 ± 6 -3.7
1.2.32.01. Cytochrome P450 17A2 4r21 Danio rerio Endoplasm. reticulum 1 0 1.0 ± 10.0 70 ± 10 -2.4
2.3.06.07. Lipase 5lip Burkholderia cepacia Secreted 1 0 9.0 ± 1.0 46 ± 2 -30.6
3.1.20.01. O2-contryphan-Vc1 2n24 Conus victoriae (Queen Victoria cone) Secreted 1 0 1.6 ± 1.0 89 ± 22 -3.6
1.2.03.02. T-cell immunoglobulin and mucin domain-containing protein 2 2or7 Mus musculus Eukaryo. plasma 1 0 0.9 ± 0.7 54 ± 6 -3.3
3.1.07.02. Membrane proximal peptide of gp41 (95-121) 2ncs Human immunodeficiency virus type 1 Viral 1 0 20.8 ± 2.0 28 ± 3 -14.6
2.2.21.02. Fibroblast growth factor 19 1pwa Homo sapiens Secreted 1 0 2.9 ± 1.5 48 ± 21 -4.7
2.2.06.02. Muscle fatty acid binding protein 1hmt Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.6 49 ± 12 -5.0
2.4.06.01. START and PH domains of collagen type IV alpha-3-binding protein 5jjd Homo sapiens Golgi 1 0 1.4 ± 2.6 48 ± 16 -4.4
2.4.16.01. Kurtoxin 1t1t Parabuthus transvaalicus Secreted 1 0 3.8 ± 0.8 88 ± 11 -5.9
3.1.06.01. Apolipoprotein A-I, peptide 190-209 1odq Homo sapiens Undefined 1 0 3.3 ± 0.7 87 ± 4 -7.1
2.2.23.01. Lipoprotein BamB, conformation 2 3p1l Escherichia coli Bact. Gram-neg outer 1 0 3.6 ± 2.8 89 ± 10 -6.4
2.1.08.01. Cytochrome c6 1c6s Thermosynechococcus elongatus Thylakoid 1 0 0.4 ± 1.7 89 ± 16 -1.3
3.1.19.01. Cephaibol C 1ob7 Acremonium tubakii Secreted 1 0 15.0 ± 2.1 55 ± 21 -15.0
2.1.02.01. Arachidonate 15-lipoxygenase 5ir4 Pseudomonas aeruginosa Secreted 1 0 4.9 ± 1.8 71 ± 2 -11.8
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4, complex with GRB10 3m7f Mus musculus Eukaryo. plasma 2 0 2.2 ± 2.0 76 ± 13 -2.7
2.1.05.01. Lanosterol synthase 1w6k Homo sapiens Endoplasm. reticulum 1 0 7.6 ± 1.0 77 ± 4 -17.8
3.1.31.01. Dermcidin, crystal structure 2ymk Homo sapiens Secreted 1 0 4.8 ± 1.3 90 ± 0 -31.0
2.3.32.01. UDP-N-acetylmuramate--L-alanine ligase 1p31 Haemophilus influenzae Bact. Gram-neg inner 1 0 4.4 ± 1.8 29 ± 14 -4.6
2.4.06.01. Phosphatidylcholine transfer protein 1ln1 Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 53 ± 16 -4.8
2.4.06.01. Lipid transport protein Mln64 (StARD3) 1em2 Homo sapiens Endosome 1 0 2.0 ± 1.1 82 ± 12 -5.0
3.1.29.01. Cathelicidin-1 2amn Gallus gallus Secreted 1 0 5.0 ± 3.3 68 ± 4 -8.7
2.4.35.01. Catalase-related protein 3e4w Mycobacterium paratuberculosis Undefined 2 0 9.6 ± 1.3 49 ± 6 -13.4
2.4.06.05. Thermoacidophile-specific fatty acid carrier 3w9k Sulfolobus tokodaii Archaebac. 1 0 2.7 ± 1.4 47 ± 4 -7.1
3.1.02.01. C-terminal helix of MCP-1 receptor 2mlo Homo sapiens Eukaryo. plasma 1 0 6.0 ± 1.6 86 ± 8 -10.1
2.1.01.01. Snake phospholipase A2 RV-7, group II 1oqs Daboia russellii siamensis Secreted 1 0 2.7 ± 1.1 87 ± 8 -7.9
2.4.34.01. Type-3 ice-structuring protein HPLC 12 4ny6 Zoarces americanus Secreted 1 0 3.3 ± 0.8 58 ± 9 -5.8
1.2.01.01. Insulin-like growth factor 1 receptor 1p4o Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.0 37 ± 11 -5.1
1.2.25.01. Phospholamban, cytoplasmic helix 1plp Homo sapiens Endoplasm. reticulum 1 0 4.0 ± 1.3 80 ± 4 -7.2
3.1.19.01. Alamethicin 1amt Trichoderma viride Secreted 1 0 10.9 ± 2.9 74 ± 13 -17.1
2.1.01.01. Acidic phospholipase A2 5 4rfp Trimeresurus stejnegeri Secreted 1 0 2.8 ± 0.3 81 ± 3 -7.1
2.2.20.01. PH domain of tyrosine-protein kinase BTK 1bwn Homo sapiens Eukaryo. plasma 2 0 15.3 ± 0.5 90 ± 10 -33.3
2.2.41.01. Reptilian defensin 2b5b Caretta caretta Secreted 1 0 1.5 ± 0.4 73 ± 1 -4.1
3.1.05.03. Peptide F 1pef Designed proteins Undefined 1 0 6.6 ± 1.3 85 ± 10 -7.8
2.3.02.03. Sphingomyelinase D 1 1xx1 Loxosceles laeta Secreted 1 0 8.1 ± 1.0 70 ± 8 -10.6
2.2.49.02. Lytic polysaccharide monooxygenase 5tkg Neurospora crassa Secreted 1 0 7.6 ± 3.6 16 ± 19 -6.5
2.1.56.01. PALS1-associated tight junction protein 1vf6 Homo sapiens Eukaryo. plasma 2 0 5.8 ± 0.4 53 ± 2 -9.4
2.1.01.01. Snake phospholipase A2, group II, acidic 1bk9 Agkistrodon halys pallas Secreted 1 0 7.3 ± 0.3 87 ± 3 -11.4
3.2.01.01. Alvinellacin 2llr Alvinella pompejana Secreted 1 0 1.6 ± 1.4 90 ± 5 -2.6
2.2.20.01. Cytohesin-3 (Grp1) 1fhx Mus musculus Eukaryo. plasma 1 0 15.0 ± 1.2 18 ± 15 -16.4
3.1.30.01. Lactoferrin-based peptide, 21-67 1z6v Homo sapiens Secreted 1 0 1.7 ± 1.4 84 ± 3 -4.9
3.2.10.02. PLP-4 peptide 6awm Designed proteins Undefined 1 0 3.5 ± 3.5 56 ± 19 -4.6
2.1.08.01. Cytochrome c552 1a8c Nitrosomonas europaea Bact. Gram-neg inner 1 0 2.7 ± 1.0 80 ± 11 -4.7
1.2.51.01. Bis(5-adenosyl)-triphosphatase ENPP4 4lqy Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 81 ± 12 -5.5
3.1.03.05. Anchor helix of 1,2-diacylglycerol 3-glucosyltransferase 1z2t Acholeplasma laidlawii Bact. Gram-pos plas. 1 0 9.6 ± 1.6 90 ± 4 -13.7
2.2.34.02. Omega-agatoxin-4A 1oav Agelenopsis aperta Secreted 1 0 4.0 ± 1.1 75 ± 14 -4.0
3.4.08.05. Bradykinin 6f3w Homo sapiens Secreted 1 0 4.8 ± 0.8 89 ± 11 -6.0
2.2.12.01. Epididymal secretory protein E1 1nep Bos taurus Secreted 1 0 8.0 ± 1.4 73 ± 14 -4.6
3.4.12.03. Bacitracin 4k7t Bacillus subtilis Secreted 1 0 9.0 ± 0.9 69 ± 8 -8.4
2.2.12.04. AP-2 complex 2vj0 Rattus norvegicus Vesicle 1 0 2.6 ± 2.0 80 ± 11 -4.8
3.4.06.01. Conomarphin 2jqc Conus marmoreus Secreted 1 0 4.1 ± 1.1 89 ± 12 -7.4
3.1.02.11. Methyl-accepting chemotaxis protein II 2l9g Escherichia coli Bact. Gram-neg inner 1 0 8.1 ± 4.2 75 ± 0 -11.7
3.1.02.01. Fourth intracellular loop of CB1 cannabinoid receptor 2mz2 Designed proteins Eukaryo. plasma 1 0 6.3 ± 1.2 80 ± 6 -7.4
2.1.01.01. Snake phospholipase A2 homolog bothropstoxin-1, group II 3i03 Bothrops jararacussu Secreted 1 0 2.5 ± 0.5 76 ± 5 -10.6
3.4.04.04. Bacillomycin Lc 2igz Bacillus subtilis Secreted 1 0 9.0 ± 2.8 57 ± 11 -6.9
2.3.12.01. Myotubularin-related protein 1 5c16 Homo sapiens Eukaryo. plasma 1 0 4.8 ± 0.7 70 ± 16 -5.3
2.4.16.14. U3-scytotoxin-Sth1h 5fzw Scytodes thoracica Secreted 1 0 3.6 ± 3.4 83 ± 9 -5.1
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 7 4bmm Trypanosoma cruzi Endoplasm. reticulum 1 0 8.8 ± 3.3 36 ± 30 -10.9
2.4.16.01. Alpha-like neurotoxin BmK-I 1djt Buthus martensii Secreted 2 0 3.8 ± 0.9 90 ± 15 -6.9
3.1.11.02. Glucagon 1kx6 Bos taurus Secreted 1 0 4.4 ± 2.0 70 ± 0 -6.4
2.3.11.01. Ferrochelatase, conformation 1 1hrk Homo sapiens Mitochon. inner 2 0 2.7 ± 0.1 90 ± 0 -9.9
3.1.20.01. Alpha-conotoxin CnIA 1b45 Conus consors (Singed cone) Secreted 1 0 0.8 ± 0.8 80 ± 20 -2.1
2.3.10.02. Beta-1,2-glucuronosyltrnansferase GumK 2q6v Xanthomonas campestris Bact. Gram-neg inner 1 0 5.2 ± 1.0 61 ± 8 -9.5
2.3.06.06. Triacylglycerol lipase 3g7n Penicillium expansum Secreted 1 0 3.8 ± 1.1 81 ± 14 -9.0
2.3.06.04. Palmitoyl-protein thioesterase 1 3gro Homo sapiens Lysosome 1 0 3.6 ± 0.1 55 ± 3 -6.8
2.2.41.02. Anthopleurin-A 1ahl Anthopleura xanthogrammica Secreted 1 0 3.7 ± 1.2 86 ± 11 -7.3
2.3.06.17. Phosphatidylcholine-sterol acyltransferase, structure 1 4x96 Homo sapiens Secreted 1 0 4.3 ± 1.1 67 ± 4 -7.9
1.2.32.01. Cytochrome P450 11B2, mitochondrial 4dvq Homo sapiens Mitochon. inner 1 0 4.8 ± 0.6 48 ± 4 -9.1
1.2.43.01. Envelope glycoprotein, West Nile virus, structure 2 2i69 West Nile virus Viral 1 0 6.7 ± 2.8 5 ± 12 -5.0
2.3.01.07. Chitinase A 1nh6 Serratia marcescens Secreted 1 0 2.7 ± 1.3 80 ± 5 -6.1
2.1.02.01. 8R-Lipoxygenase, central and C-terminal domains 3fg3 Plexaura homomalla Eukaryo. plasma 1 0 5.0 ± 0.6 86 ± 5 -9.3
2.3.16.06. ADP-ribosylation factor 1 (ARF1), different conformation 2ksq Saccharomyces cerevisiae Golgi 1 0 4.7 ± 0.1 62 ± 0 -10.4
1.2.50.01. Sticholysin-1 2ks4 Stoichactis helianthus Secreted 1 0 2.3 ± 2.2 6 ± 24 -5.7
3.4.07.02. Compstatin 1a1p Designed proteins Undefined 1 0 3.4 ± 1.9 72 ± 18 -5.6
1.2.64.01. Selenoprotein S 5kiu Homo sapiens Endoplasm. reticulum 1 0 2.3 ± 4.2 89 ± 0 -5.2
2.4.11.01. Hellethionin D 1nbl Helleborus purpurascens Secreted 1 0 2.2 ± 0.9 45 ± 9 -7.4
2.3.06.17. Phosphatidylcholine-sterol acyltransferase, structure 3 5bv7 Homo sapiens Secreted 1 0 2.8 ± 3.1 76 ± 15 -6.1
3.1.02.07. Sodium/hydrogen exchanger 1, TM helices 2kbv Homo sapiens Eukaryo. plasma 1 0 2.7 ± 6.9 74 ± 4 -4.9
2.2.13.01. Cellulosomal scaffoldin 2xbt Bacteroides cellulosolvens Secreted 1 0 4.4 ± 0.3 84 ± 14 -5.8
2.2.06.02. Cellular retinol-binding protein II 1crb Rattus norvegicus Eukaryo. plasma 1 0 2.4 ± 1.7 52 ± 19 -5.3
1.2.39.01. Leucyl-cystinyl aminopeptidase, structure 2 5mj6 Homo sapiens Eukaryo. plasma 1 0 1.8 ± 1.4 76 ± 4 -3.5
3.1.04.10. TAR DNA-binding protein 43, peptide 307-349 2n2c Homo sapiens Nuclear inner 1 0 7.7 ± 0.7 89 ± 6 -13.4
2.2.41.01. Defensin-like peptide 1 1b8w Ornithorhynchus anatinus Secreted 1 0 1.8 ± 0.6 84 ± 2 -4.4
2.3.24.01. Phosphonoacetaldehyde hydrolase 1rdf Bacillus cereus Undefined 1 0 4.3 ± 0.9 68 ± 4 -5.1
3.2.05.02. Microcin J25, peptide 38-58 1q71 Escherichia coli Secreted 1 0 3.3 ± 3.2 75 ± 17 -5.2
1.2.42.01. Sphingomyelin phosphodiesterase 5fic Mus musculus Secreted 1 0 6.7 ± 1.2 67 ± 0 -9.8
2.2.06.02. Fatty acid-binding protein 9 4a60 Homo sapiens Eukaryo. plasma 1 0 3.2 ± 1.1 38 ± 6 -4.6
2.3.06.07. Organic solvent tolerant lipase 42 4fkb Bacillus sp. Secreted 1 0 5.0 ± 0.7 26 ± 3 -6.9
2.2.07.01. Acidic stress response factor 3hpe Helicobacter pylori Bact. Gram-neg inner 1 0 3.0 ± 0.7 34 ± 8 -6.1
1.2.55.01. Neutral ceramidase 4wgk Homo sapiens Eukaryo. plasma 1 0 4.1 ± 0.5 80 ± 2 -10.0
2.3.16.06. ADP-ribosylation factor-like protein 8A 2h18 Homo sapiens Endosome 1 0 1.2 ± 3.6 58 ± 28 -2.6
3.1.16.01. Lactococcin-G subunit alpha 2jpj Lactococcus lactis Secreted 1 0 5.8 ± 2.9 77 ± 3 -5.9
2.2.12.01. Lymphocyte antigen 96, structure 2 4g8a Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.3 67 ± 6 -3.8
3.4.04.01. Daptomycin, Ca-bound 1t5n Streptomyces roseosporus Secreted 1 0 8.6 ± 2.0 21 ± 24 -9.0
3.1.21.10. Pilosulin-1 5x3l Myrmecia pilosula Secreted 1 0 7.6 ± 3.2 82 ± 7 -8.5
1.2.04.01. Integrin beta-3/alpha-V complex 3ije Homo sapiens Eukaryo. plasma 2 0 6.1 ± 2.1 13 ± 14 -9.0
1.2.32.01. Cytochrome P450 19A1 (estrogen synthetase) 3eqm Homo sapiens Endoplasm. reticulum 1 0 6.1 ± 1.2 58 ± 8 -12.4
3.1.21.03. Melittin 2mlt Apis mellifera Secreted 1 0 15.0 ± 1.0 65 ± 11 -12.0
2.2.20.01. PH domain containing retinal protein 1 2d9v Mus musculus Eukaryo. plasma 1 0 1.3 ± 1.3 58 ± 14 -5.1
3.1.10.01. Competence stimulating peptide 2i2h Streptococcus mutants Secreted 1 0 8.2 ± 0.5 74 ± 7 -12.5
3.1.28.06. Magainin analogue 2 5cgo Designed proteins Undefined 2 0 3.8 ± 0.9 89 ± 2 -10.8
2.3.06.10. Lipase 2fx5 Pseudomonas mendocina Secreted 1 0 5.5 ± 1.0 50 ± 5 -8.4
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 1 2xar Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 1.6 69 ± 7 -6.1
2.2.02.03. Serine protease/helicase NS3 2whx Dengue virus Endoplasm. reticulum 2 0 4.4 ± 2.3 68 ± 9 -5.6
2.1.01.01. Snake phospholipase A2, group I, isoform 1 1tc8 Bungarus caeruleus Secreted 1 0 3.1 ± 1.4 89 ± 11 -5.0
3.1.20.01. Alpha4/6-conotoxin TxIC 2m3i Conus lividus Secreted 1 0 5.3 ± 1.0 77 ± 10 -4.9
2.2.34.02. Mu-theraphotoxin-Hhn2b 1nix Haplopelma hainanum (Chinese bird spider) Secreted 1 0 3.6 ± 1.1 64 ± 5 -5.5
3.2.07.02. Shaker B channel peptide 2lny Designed proteins Undefined 1 0 4.1 ± 3.6 69 ± 18 -4.1
2.2.05.01. Azurin iso-2 1cuo Methylomonas sp. Bact. Gram-neg inner 1 0 1.4 ± 1.6 69 ± 15 -4.3
1.2.06.01. Spore surface protein Bcla 1wck Bacillus anthracis Bact. Gram-pos plas. 3 0 3.3 ± 0.2 8 ± 5 -8.9
3.1.27.01. Pardaxin 2kns Pardachirus marmoratus Secreted 1 0 4.0 ± 0.7 84 ± 7 -11.1
2.4.16.03. Toxin SsTx 5x0s Scolopendra subspinipes Secreted 1 0 3.6 ± 1.2 56 ± 4 -7.4
2.2.06.01. Retinol binding protein 4, structure 1 1rbp Homo sapiens Secreted 1 0 3.5 ± 0.8 70 ± 6 -5.8
1.3.25.01. LukF prepore, hetero-octamer (C+B) 4p1x Staphylococcus aureus Secreted 8 0 4.2 ± 0.2 89 ± 1 -19.4
2.2.34.02. Mu-theraphotoxin-Hhn2a 2jtb Haplopelma hainanum (Chinese bird spider) Secreted 1 0 3.4 ± 1.5 74 ± 12 -4.7
2.2.34.02. Omega-theraphotoxin-Hh1a 1y29 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 0.7 ± 1.3 83 ± 17 -2.7
2.2.34.11. Varv peptide F 3e4h Viola arvensis Secreted 1 0 4.2 ± 3.0 87 ± 43 -5.6
3.1.29.01. EFK17DA peptide derived from cathelicidin LL-37 5xrx Homo sapiens Secreted 1 0 3.6 ± 1.2 73 ± 8 -6.1
1.2.39.01. Glutamyl aminopeptidase 4kxd Homo sapiens Eukaryo. plasma 1 0 3.3 ± 0.8 77 ± 2 -4.2
2.3.06.08. Pancreatic lipase, complex with colipase from Pig 1lpb Homo sapiens Secreted 2 0 9.2 ± 0.4 89 ± 2 -24.2
2.2.41.01. Beta-defensin 106 2lwl Homo sapiens Secreted 1 0 4.0 ± 1.5 70 ± 9 -6.4
2.3.18.01. Choline O-acetyltransferase, different conformation 1t1u Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 1.7 73 ± 15 -6.8
1.2.32.01. Cholesterol side-chain cleavage enzyme (P450 11A1), complex with adrenodoxin 3n9y Homo sapiens Mitochon. inner 1 0 4.1 ± 0.6 49 ± 5 -6.2
3.1.11.03. Obestatin 2jsi Mus musculus Secreted 1 0 2.0 ± 3.3 85 ± 13 -3.1
2.1.18.01. Annexin XII 1dm5 Hydra vulgaris Eukaryo. plasma 3 0 2.7 ± 1.0 90 ± 7 -10.2
2.1.24.01. Saposin-like domain of plant aspartic protease 3rfi Solanum tuberosum Secreted 1 0 5.6 ± 3.2 66 ± 3 -9.1
2.1.24.01. Saposin B (peptide 195-273), structure 2 4v2o Homo sapiens Lysosome 2 0 1.5 ± 1.0 51 ± 4 -3.2
1.2.38.03. Endo-type membrane-bound lytic murein transglycosylase A 2y8p Escherichia coli Bact. Gram-neg outer 1 0 0.0 ± 3.6 86 ± 15 -2.2
2.3.06.06. Lipase B, open state 1lbs Candida antarctica Secreted 1 0 3.7 ± 1.0 76 ± 6 -12.7
2.2.35.01. Pneumolysin, structure 2 5cr6 Streptococcus pneumoniae Secreted 1 0 4.3 ± 1.9 24 ± 3 -6.4
2.2.20.01. Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 2da0 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 2.5 64 ± 20 -2.5
2.3.11.01. Ferrochelatase, conformation 2 (with porphyrin bound) 4klr Homo sapiens Mitochon. inner 2 0 1.3 ± 0.0 90 ± 1 -8.4
1.2.43.06. Outer capsid protein VP4, trimer 2b4i Rotavirus A Viral 3 0 2.9 ± 0.3 2 ± 0 -11.7
2.4.33.02. Collagenase 2y3u Clostridium histolyticum Secreted 1 0 3.0 ± 1.0 89 ± 4 -5.4
2.3.06.05. Carboxylesterase 2 1auo Pseudomonas fluorescens Bact. Gram-neg inner 1 0 1.7 ± 3.0 33 ± 21 -3.4
2.2.20.01. Pleckstrin 1pls Homo sapiens Eukaryo. plasma 1 0 3.6 ± 2.0 61 ± 19 -3.8
2.1.54.01. Programmed cell death protein 10 3ajm Homo sapiens Golgi 2 0 2.7 ± 0.4 86 ± 7 -5.8
2.4.16.01. Beta-insect excitatory toxin BmK IT-AP 1t0z Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 3.9 ± 1.2 79 ± 10 -7.2
3.1.05.05. Anticoccidial peptide PW2 2jq2 Designed proteins Undefined 1 0 6.2 ± 2.3 67 ± 36 -4.5
2.2.45.01. Outer membrane protein IcsA autotransporter 3ml3 Shigella flexneri Bact. Gram-neg outer 1 0 3.4 ± 0.5 65 ± 2 -6.2
3.1.07.09. Membrane fusion protein p15 2mns Baboon orthoreovirus Eukaryo. plasma 1 0 9.3 ± 7.0 86 ± 4 -9.4
2.2.20.01. PH-like domain of Lam6 5yqr Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.6 ± 1.6 83 ± 6 -4.5
3.1.11.03. Motilin 1lbj Homo sapiens Secreted 1 0 8.6 ± 1.6 51 ± 18 -4.9
2.2.34.07. Asteropsin G 2n3p Asteropus sp. Secreted 1 0 8.0 ± 1.4 37 ± 17 -5.3
3.1.04.03. Viral protein R, peptide 52-96, dimer, different strain 1x9v Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.2 ± 0.7 86 ± 4 -8.6
1.2.40.01. Mitochondria fission 1 protein, crystal structure 1nzn Homo sapiens Mitochon. outer 1 0 6.1 ± 1.4 72 ± 8 -9.3
2.1.24.01. Saposin-like protein Ac-SLP-1 3s64 Ancylostoma caninum Secreted 1 0 4.2 ± 2.2 53 ± 16 -4.5
2.1.07.01. Nonaheme cytochrome c 1duw Desulfovibrio desulfuricans Bact. Gram-neg inner 1 0 5.1 ± 0.4 87 ± 10 -4.9
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 436-456 1bts Homo sapiens Eukaryo. plasma 1 0 9.2 ± 0.3 84 ± 2 -14.8
1.1.01.03. Glucagon-like peptide 1 receptor, extracellular domain 5e94 Homo sapiens Eukaryo. plasma 1 0 3.4 ± 10.0 36 ± 6 -7.5
2.1.53.01. Peroxisomal biogenesis factor 19 2wl8 Homo sapiens Peroxisome 1 0 8.3 ± 0.8 79 ± 14 -9.9
2.4.16.04. Defensin-like protein 1 1gps Triticum aestivum Secreted 1 0 3.4 ± 1.3 22 ± 9 -3.9
2.2.05.02. Mavicyanin 1ws8 Cucurbita pepo Undefined 1 0 3.7 ± 0.5 31 ± 8 -6.5
3.4.02.03. Nisin-Lipid II complex in DMSO solution 1wco Lactococcus lactis Secreted 1 0 8.1 ± 1.0 90 ± 5 -8.0
2.2.35.01. Pneumolysin, structure 4 5aod Streptococcus pneumoniae Secreted 1 0 4.1 ± 1.6 26 ± 4 -6.1
3.1.02.02. Voltage sensor of calcium-activated potassium channel 2k44 Homo sapiens Eukaryo. plasma 1 0 7.5 ± 3.0 54 ± 4 -9.8
2.2.06.01. Prostaglandin-H2 D-isomerase 2ktd Mus musculus Endoplasm. reticulum 1 0 0.0 ± 1.4 73 ± 14 -2.2
2.3.06.02. Antigen 85c, conformation 1 1va5 Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 4.2 ± 0.2 34 ± 3 -8.2
2.2.59.01. Zymogen granule membrane protein 16 3vy7 Homo sapiens Secreted 1 0 3.6 ± 2.1 54 ± 15 -4.6
2.2.20.02. Disabled homolog 1 1nu2 Mus musculus Eukaryo. plasma 1 0 14.8 ± 1.1 46 ± 12 -17.6
2.3.16.04. EH domain-containing protein 2 2qpt Mus musculus Endosome 2 0 4.5 ± 2.1 20 ± 14 -7.8
2.2.33.01. Antimicrobial peptide 2 1mmc Amaranthus caudatus (Inca-wheat) Secreted 1 0 1.6 ± 1.2 46 ± 9 -3.9
2.2.34.11. Melanocortin agonist based on kalata-B1 2lur Designed proteins Undefined 1 0 6.5 ± 1.0 74 ± 21 -6.7
1.2.39.01. Leucyl-cystinyl aminopeptidase, structure 1 5c97 Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.0 76 ± 3 -7.6
3.1.21.02. Mastoparan 2czp Vespa xanthoptera Secreted 1 0 5.2 ± 1.6 88 ± 16 -9.8
2.1.19.01. Antimicrobial peptide Tk-Amp-X2 2m6a Hordeum vulgare Secreted 1 0 1.2 ± 1.0 65 ± 7 -3.4
1.2.03.07. Netrin receptor UNC5B 3g5b Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 2.5 90 ± 14 -8.5
2.1.24.01. NK-lysin 1nkl Sus scrofa Secreted 1 0 2.8 ± 1.5 37 ± 12 -5.4
2.4.51.01. Heme acquisition protein HasA, alternative position of heme 3mol Pseudomonas aeruginosa Secreted 1 0 2.9 ± 0.6 40 ± 5 -5.8
2.2.27.01. C1 domanin of SH3 and cysteine-rich domain-containing protein 3 2db6 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 0.1 75 ± 0 -4.8
2.2.26.01. FYVE domain of Vps27 protein 1vfy Saccharomyces cerevisiae Vacuole 1 0 3.7 ± 1.8 24 ± 19 -4.2
2.4.16.03. Potassium channel toxin gamma-KTx 1.1 1ne5 Centruroides noxius (Mexican scorpion) Secreted 1 0 3.9 ± 1.0 62 ± 2 -5.2
3.1.05.03. Lavracin 2n8d Designed proteins Undefined 1 0 5.1 ± 1.2 89 ± 13 -5.7
2.3.06.05. Copper inducible hydrolase YahD 3og9 Lactococcus lactis Bact. Gram-pos plas. 1 0 1.4 ± 1.1 33 ± 10 -4.0
3.1.21.02. Mastoparan-L 1d7n Vespula lewisii Secreted 1 0 6.5 ± 1.7 82 ± 16 -7.5
2.1.25.05. Bacteriocin BacSp222 5lwc Staphylococcus pseudintermedius Secreted 1 0 4.3 ± 3.0 30 ± 7 -5.1
2.1.01.01. Phospholipase A2, group X 1le6 Homo sapiens Secreted 1 0 7.4 ± 0.9 78 ± 6 -13.2
3.4.08.02. Somatostatin 2mi1 Homo sapiens Secreted 1 0 5.6 ± 1.5 43 ± 15 -6.2
2.3.08.02. Cytosolic phospholipase A2, group IVA 1cjy Homo sapiens Vesicle 1 0 5.8 ± 1.0 70 ± 9 -9.9
2.1.29.02. Apolipoprotein A-II 2ou1 Homo sapiens Secreted 2 0 2.7 ± 1.2 87 ± 2 -17.7
2.3.10.01. Peptidoglycan biosynthesis glycosyltransferase MurG, conformation 2 1f0k Escherichia coli Bact. Gram-neg inner 1 0 5.3 ± 1.2 55 ± 7 -8.6
2.3.06.08. Pancreatic lipase-related protein 1 1rp1 Canis lupus familiaris Secreted 1 0 6.3 ± 1.0 79 ± 4 -7.5
2.2.06.01. Retinol binding protein 4, structure 3 4o9s Homo sapiens Secreted 1 0 3.8 ± 3.8 70 ± 4 -5.1
2.2.04.01. Retinoid isomerohydrolase, conformation 3 4f30 Bos taurus Eukaryo. plasma 1 0 3.4 ± 1.4 61 ± 7 -10.9
3.1.07.05. Nonstructural protein 2a, segment 1194-1221 2m0s Dengue virus Endoplasm. reticulum 1 0 7.4 ± 3.6 79 ± 1 -7.1
2.2.34.11. Palicourein 1r1f Palicourea condensata Secreted 1 0 4.8 ± 1.4 70 ± 19 -5.0
2.2.34.02. U1-theraphotoxin-Cj1a 2aap Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.6 ± 0.7 82 ± 5 -4.9
2.1.02.01. Seed lipoxygenase-D 2iuk Glycine max Eukaryo. plasma 1 0 3.7 ± 1.7 85 ± 8 -6.2
2.2.34.02. Robustoxin 1qdp Atrax robustus Secreted 1 0 1.8 ± 1.9 86 ± 18 -5.0
2.3.06.06. Lipase 3zpx Ustilago maydis Secreted 1 0 5.8 ± 0.8 88 ± 1 -14.0
2.2.11.01. E3 ubiquitin-protein ligase SMURF2 2jqz Homo sapiens Eukaryo. plasma 1 0 4.2 ± 1.8 23 ± 17 -5.6
2.1.08.01. Mitochondrial cytochrome c 1hrc Equus caballus Mitochon. inner 1 0 2.1 ± 1.0 80 ± 16 -2.6
3.1.07.03. Hemagglutinin, peptide 330-349, F9A 2jrd Influenza virus Viral 1 0 8.1 ± 4.0 71 ± 5 -6.8
3.1.20.01. Alpha-conotoxin OmIA 2gcz Conus omaria (Omaria cone) Secreted 1 0 3.0 ± 1.5 62 ± 11 -3.7
2.3.05.03. Glycerol-3-phosphate dehydrogenase (GlpD) 2qcu Escherichia coli Bact. Gram-neg inner 1 0 4.5 ± 1.5 74 ± 11 -8.4
2.2.11.01. Protein kinase C alpha, complex with phosphatidyl serine 1dsy Rattus norvegicus Eukaryo. plasma 1 0 0.9 ± 1.5 18 ± 16 -3.0
3.1.21.09. Cytotoxic linear peptide IsCT 1t51 Opisthacanthus madagascariensis Secreted 1 0 4.1 ± 0.6 87 ± 11 -10.5
2.2.03.01. Cathepsin D 1lyb Homo sapiens Lysosome 2 0 7.0 ± 0.6 87 ± 5 -11.2
2.2.41.01. Beta-defensin 1 1ijv Homo sapiens Secreted 1 0 3.5 ± 1.9 74 ± 17 -5.4
2.2.41.01. Paneth cell-specific alpha-defensin 1 2mxq Equus caballus Secreted 1 0 3.1 ± 0.6 75 ± 5 -7.2
2.3.06.01. Acetylcholinesterase 4ey4 Homo sapiens Eukaryo. plasma 1 0 3.2 ± 0.5 33 ± 2 -8.4
1.2.33.02. Protoporphyrinogen oxidase 3nks Homo sapiens Mitochon. inner 1 0 4.8 ± 1.0 59 ± 3 -9.6
3.1.01.02. Leader peptide of patellamide protein 2kya Prochloron didemni Secreted 1 0 5.8 ± 0.5 86 ± 4 -8.8
2.1.20.01. Coagulation factor XIV (protein C) in complex with its receptor 1lqv Homo sapiens Eukaryo. plasma 2 0 3.4 ± 3.9 53 ± 14 -5.6
2.2.12.04. ADP-ribosylation factor binding protein Gga3 domain 1p4u Homo sapiens Golgi 1 0 6.5 ± 1.1 71 ± 11 -6.5
3.1.25.01. Latarcin-1 (M-zodatoxin-Lt1a) 2pco Lachesana tarabaevi (Spider) Secreted 1 0 10.1 ± 0.8 77 ± 6 -9.4
2.2.27.01. C1 domain of protein kinase C alpha 2eli Homo sapiens Eukaryo. plasma 1 0 2.1 ± 0.4 23 ± 4 -7.4
2.3.06.07. Lipase, open (active) state 1ex9 Pseudomonas aeruginosa Secreted 1 0 11.0 ± 1.0 52 ± 5 -30.0
2.2.34.01. Conotoxin muOxi-GVIIJ 2n8h Conus geographus (Geography cone) Secreted 1 0 4.0 ± 1.0 43 ± 5 -4.1
1.2.03.02. Hepatitis A virus cellular receptor 1 homolog 2or8 Mus musculus Eukaryo. plasma 1 0 4.2 ± 2.4 51 ± 16 -3.9
1.2.45.02. Small hydrophobic protein, peptide 39-49 2nb8 Human respiratory syncytial virus Viral 1 0 8.5 ± 1.2 57 ± 13 -5.9
2.1.60.03. Cysteine-rich venom protein 1rc9 Trimeresurus stejnegeri Secreted 1 0 3.9 ± 0.7 73 ± 5 -5.1
2.2.06.02. Muscle fatty acid binding protein 1bwy Bos taurus Eukaryo. plasma 1 0 4.8 ± 1.3 71 ± 12 -6.6
2.3.06.01. Acetylcholinesterase 5x61 Anopheles gambiae (African malaria mosquito) Eukaryo. plasma 1 0 2.6 ± 1.5 37 ± 4 -4.0
2.4.04.01. Sphingomyelin phosphodiesterase 3 5uvg Homo sapiens Golgi 1 0 2.9 ± 1.6 59 ± 13 -5.1
2.4.16.01. Alpha-toxin Cn12 1pe4 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.1 ± 2.3 17 ± 13 -3.1
3.1.06.01. Apolipoprotein E, peptide 281-304 1oef Homo sapiens Undefined 1 0 4.8 ± 0.9 88 ± 19 -5.5
2.1.08.01. Quinohemoprotein alcohol dehydrogenase ADH IIB 1kv9 Pseudomonas putida Bact. Gram-neg outer 1 0 1.7 ± 1.1 77 ± 22 -5.9
2.1.08.01. Cytochrome c6 1f1f Arthrospira maxima Thylakoid 1 0 4.8 ± 1.6 80 ± 15 -3.5
3.1.19.01. Antiamoebin I 1joh Emercelliopsis sp. Secreted 1 0 8.1 ± 0.8 82 ± 5 -11.7
3.2.10.01. PawS derived peptide 20 2ndn Zinnia haageana Secreted 1 0 1.8 ± 0.7 83 ± 11 -4.6
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4 3b7y Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.5 9 ± 6 -4.1
1.2.32.01. Cytochrome P450 2C5 1nr6 Oryctolagus cuniculus Endoplasm. reticulum 1 0 10.6 ± 1.0 54 ± 18 -9.1
2.4.06.01. Steroidogenic acute regulatory protein, mitochondrial 3p0l Homo sapiens Mitochon. outer 1 0 3.0 ± 1.3 76 ± 10 -4.7
2.3.02.02. Phosphatidylinositol-specific phospholipase C 4f2t Staphylococcus aureus Secreted 1 0 4.3 ± 0.5 65 ± 5 -7.8
2.1.32.01. Alpha-synuclein 1xq8 Homo sapiens Eukaryo. plasma 1 0 8.7 ± 1.1 87 ± 4 -15.7
2.1.21.02. Matrix protein p10, myristoylated dimer, different strain 5hyb Mouse mammary tumor virus Eukaryo. plasma 2 0 12.9 ± 10.0 73 ± 10 -9.4
2.2.26.01. Early endosome antigen 1 (EEA1), model of dimer with lipids 1joc Homo sapiens Endosome 2 0 15.0 ± 0.4 2 ± 11 -34.0
3.1.29.01. Cathelicidin-6 2ket Bos taurus Secreted 1 0 7.1 ± 0.7 82 ± 3 -13.6
2.4.23.01. Methyl-accepting chemotaxis protein 3eee Thermoanaerobacter tengcongensis Undefined 1 0 3.2 ± 0.9 81 ± 4 -5.9
3.1.04.06. Amyloidogenic peptide (248-286) of prostatic acid phosphatase 2l3h Homo sapiens Eukaryo. plasma 1 0 4.5 ± 2.7 86 ± 0 -4.2
2.1.01.01. Snake phospholipase A2, group I 1s6b Naja sagittifera Secreted 1 0 3.0 ± 1.1 81 ± 10 -7.5
2.4.34.01. Ice-structuring protein RD3 1c89 Lycodichthys dearborni Secreted 1 0 3.0 ± 1.0 85 ± 9 -8.7
1.2.01.01. Macrophage colony-stimulating factor 1 receptor 3bea Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.5 54 ± 19 -4.2
2.1.20.01. Osteocalcin 4mzz Bos taurus Secreted 1 0 1.8 ± 1.1 43 ± 8 -3.0
2.2.11.01. Protein unc-13 homolog A, C2A domain 2cjs Rattus norvegicus Eukaryo. plasma 1 0 3.5 ± 2.0 47 ± 12 -5.0
2.4.07.01. PX domain of sorting nexin-10 4on3 Homo sapiens Endosome 1 0 5.2 ± 1.6 69 ± 5 -7.7
3.1.21.06. Spinigerin 1zrv Pseudacanthotermes spiniger Secreted 1 0 2.1 ± 3.4 77 ± 5 -3.9
3.1.21.01. Cecropin (1-7)-melittin (2-9) hybrid 2jmy Designed proteins Undefined 1 0 6.5 ± 3.3 77 ± 7 -6.1
2.1.03.01. Phospholipase C 1p6d Bacillus cereus Secreted 1 0 2.8 ± 1.0 52 ± 6 -8.4
3.1.15.05. Enterocin K1 5l82 Enterococcus faecium Secreted 1 0 7.0 ± 3.6 27 ± 6 -6.3
2.4.14.01. 1-acyl-sn-glycerol-3-phosphate acyltransferase 5kym Thermotoga maritima Bact. Gram-neg inner 1 0 20.2 ± 1.0 28 ± 2 -32.3
2.3.16.07. Ras-related protein Rab-9A 1wms Homo sapiens Eukaryo. plasma 1 0 1.9 ± 0.8 48 ± 7 -5.0
3.1.07.06. NS2 protease, segment 836-868 of polyprotein 2kwt Hepatitis C virus Endoplasm. reticulum 1 0 9.5 ± 3.6 81 ± 3 -15.7
2.1.01.01. Snake phospholipase A2, group II, B 1jia Agkistrodon halys pallas Secreted 1 0 3.3 ± 0.5 78 ± 4 -11.2
3.2.01.04. Symmetrical θ-defensin, BTD-2 2lye Macaca mulatta Secreted 1 0 0.4 ± 2.9 80 ± 22 -1.5
2.1.45.01. Kinetoplastid membrane protein 11 5y70 Trypanosoma brucei Eukaryo. plasma 1 0 2.5 ± 0.4 53 ± 4 -4.9
2.2.03.01. Saccharopepsin 1fq5 Saccharomyces cerevisiae Vacuole 1 0 3.8 ± 0.8 84 ± 6 -8.1
3.1.28.01. Dermaseptin-4 2dd6 Phyllomedusa sauvagei (Sauvage's leaf frog) Secreted 1 0 4.2 ± 1.6 76 ± 6 -7.0
3.2.10.02. PLP-12 peptide 6awk Designed proteins Undefined 1 0 1.8 ± 1.8 80 ± 12 -4.4
2.1.08.01. Cytochrome c2 1co6 Rhodopseudomonas viridis Bact. Gram-neg inner 1 0 1.4 ± 0.7 78 ± 10 -3.3
1.2.04.01. Integrin alpha-L, cytoplasmic domain (1113-1170) 2k8o Homo sapiens Eukaryo. plasma 1 0 2.2 ± 0.7 65 ± 3 -3.7
1.2.32.01. Fatty-acid peroxygenase 1izo Bacillus subtilis Bact. Gram-pos plas. 1 0 1.2 ± 0.3 76 ± 1 -5.5
2.1.01.01. Phospholipase A2 BnSP-7 1pa0 Bothrops neuwiedi pauloensis Secreted 1 0 2.8 ± 1.0 78 ± 10 -6.9
2.3.25.01. Acyloxyacyl hydrolase, structure 1 5w7b Oryctolagus cuniculus Secreted 2 0 8.2 ± 0.8 87 ± 1 -8.8
2.3.10.06. Glycosyltransferase PglH (WlaC) 6eji Campylobacter jejuni Bact. Gram-neg inner 1 0 5.6 ± 1.6 49 ± 1 -15.6
2.3.06.08. Pancreatic lipase 1hpl Equus caballus Secreted 1 0 3.8 ± 0.3 80 ± 5 -8.1
3.2.05.03. Bicyclic peptide BI-32169 3njw Streptomyces sp. Secreted 1 0 6.1 ± 0.3 86 ± 3 -9.9
2.4.07.01. PX domain of C2alpha-PI3 kinase 2ar5 Homo sapiens Eukaryo. plasma 1 0 5.6 ± 0.9 83 ± 17 -3.7
1.2.17.02. Synaptobrevin homolog YKT6 3kyq Rattus norvegicus Vesicle 1 0 2.5 ± 2.0 53 ± 8 -4.9
2.2.34.01. Kappa-conotoxin PVIIA 1av3 Conus purpurascens (Purple cone) Secreted 1 0 3.4 ± 1.9 77 ± 7 -3.2
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 3 5fih Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.5 ± 0.6 89 ± 1 -5.3
2.1.01.01. Snake phospholipase A2 crotoxin basic chain 2, group II 2qog Crotalus durissus terrificus Secreted 1 0 2.1 ± 1.1 84 ± 8 -7.2
3.4.12.05. Ramoplanin A2 1dsr Actinoplanes sp. Secreted 1 0 6.9 ± 0.4 55 ± 22 -4.7
2.2.34.02. Delta-theraphotoxin-Hm1a 2n6o Heteroscodra maculata Secreted 1 0 4.0 ± 3.4 76 ± 13 -6.2
1.2.53.01. Squalene synthase, conformation 3 3weh Homo sapiens Endoplasm. reticulum 1 0 1.4 ± 2.5 90 ± 26 -3.8
2.4.16.01. Neurotoxin 1dq7 Buthus tamulus Secreted 1 0 5.9 ± 1.8 88 ± 18 -8.1
2.2.34.06. Ginsentide 2ml7 Panax ginseng Secreted 1 0 7.6 ± 1.1 54 ± 8 -7.7
3.1.01.06. Protein PB1-F2, mitochondrial targeting peptide (50-87) 2hn8 Influenza virus Mitochon. inner 1 0 5.1 ± 3.8 86 ± 1 -10.9
2.1.21.04. Matrix protein p19 1a6s Rous sarcoma virus Viral 1 0 3.1 ± 2.7 89 ± 14 -3.6
3.1.14.01. Uperolein 2gfr Uperoleia rugosa (Wrinkled toadlet) Secreted 1 0 6.4 ± 1.2 88 ± 9 -8.2
2.3.10.03. Heptosyltransferase WaaC 2h1h Escherichia coli Bact. Gram-neg inner 1 0 5.0 ± 1.1 67 ± 5 -9.1
2.3.06.06. Lipase 2 3o0d Yarrowia lipolytica Secreted 1 0 6.8 ± 2.4 79 ± 26 -9.4
2.1.24.01. Saposin A (peptide 60-140) 2dob Homo sapiens Lysosome 1 0 2.0 ± 2.5 70 ± 29 -4.2
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 5 4by0 Trypanosoma cruzi Eukaryo. plasma 1 0 4.8 ± 2.6 88 ± 7 -1.6
2.2.41.02. Anthopleurin-B 1apf Anthopleura xanthogrammica Secreted 1 0 6.4 ± 1.3 78 ± 19 -7.1
2.3.06.06. Lipase 4l3w Rhizopus chinensis Secreted 1 0 3.2 ± 0.7 31 ± 2 -6.5
2.3.10.07. Lipopolysaccharide biosynthesis protein RfaG, 103-131 2n58 Escherichia coli Bact. Gram-neg inner 1 0 4.5 ± 1.1 64 ± 7 -6.3
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 2 3c6e Dengue virus Viral 1 0 2.9 ± 2.7 42 ± 5 -3.6
2.3.01.07. Chitinase B 1h0i Serratia marcescens Secreted 1 0 3.8 ± 1.4 70 ± 12 -5.2
2.2.20.01. PH domain of fermitin family homolog 3 5l81 Mus musculus Eukaryo. plasma 1 0 3.8 ± 2.2 59 ± 7 -4.2
2.2.44.01. DENN domain-containing and Rab6-interacting proteins 3cwz Mus musculus Golgi 2 0 3.7 ± 1.0 77 ± 2 -5.2
3.1.13.01. Proadrenomedullin N-20 terminal peptide 2fly Homo sapiens Secreted 1 0 4.8 ± 4.0 88 ± 2 -7.5
3.1.05.06. Transportan 1smz Designed proteins Undefined 1 0 9.1 ± 0.8 87 ± 7 -8.9
3.1.15.01. Leucocin A 1cw6 Leuconostoc gelidum Secreted 1 0 3.6 ± 1.1 90 ± 16 -6.2
3.1.11.06. Parathyroid hormone-related peptide, structure 1 1bzg Homo sapiens Secreted 1 0 6.4 ± 2.2 54 ± 18 -6.4
1.2.30.01. Potassium voltage-gated channel subfamily E member 1 2k21 Homo sapiens Eukaryo. plasma 1 0 12.1 ± 0.4 54 ± 2 -24.7
1.2.55.01. Neutral ceramidase, structure 1 2zws Pseudomonas aeruginosa Secreted 1 0 3.1 ± 2.4 77 ± 3 -8.1
2.2.06.02. Cellular retinol-binding protein II 1kqw Danio rerio Eukaryo. plasma 1 0 3.1 ± 1.3 45 ± 13 -4.9
2.1.64.01. AFMP4P 5j5k Aspergillus fumigatus Eukaryo. plasma 1 0 3.9 ± 1.9 73 ± 13 -6.1
2.2.06.02. Fatty acid bindin protein, isoform B 5gge Drosophila melanogaster Nuclear inner 1 0 3.5 ± 3.5 52 ± 7 -7.0
2.4.16.02. Defensin MGD-1 1fjn Mytilus galloprovincialis (Mediterranean mussel) Secreted 1 0 1.5 ± 1.4 43 ± 12 -3.0
2.3.17.01. Phospho-2-dehydro-3-deoxyheptonate aldolase 1of8 Saccharomyces cerevisiae Undefined 2 0 7.2 ± 0.4 80 ± 6 -9.3
1.2.32.01. Cytochrome P450 120a1, different conformation 2ve3 Synechocystis sp. Thylakoid 1 0 5.2 ± 1.5 52 ± 15 -6.8
2.1.62.02. Subtilosin A 1pxq Bacillus subtilis Secreted 1 0 7.6 ± 0.8 86 ± 3 -9.3
2.2.22.01. Hydrophobin NC2, structure 1 4aog Neurospora crassa Secreted 1 0 3.9 ± 1.7 85 ± 7 -4.6
2.2.06.02. Fatty acid binding protein 6, ileal (Gastrotropin) 3elz Danio rerio Eukaryo. plasma 1 0 1.1 ± 0.9 85 ± 6 -2.4
2.3.16.05. ATPase Get3, complex with Get1 cytosolic domain 3sja Saccharomyces cerevisiae Endoplasm. reticulum 4 0 6.4 ± 1.6 89 ± 45 -8.1
1.2.22.01. Bcl-2-like protein 2 1o0l Homo sapiens Mitochon. outer 1 0 1.7 ± 2.3 86 ± 14 -3.7
2.2.46.01. Low molecular mass 30 kDa lipoprotein 19G1 4iy8 Bombyx mori Secreted 1 0 4.3 ± 1.2 31 ± 8 -4.2
2.2.07.01. Protein yceI 1y0g Escherichia coli Bact. Gram-neg inner 1 0 4.2 ± 1.5 24 ± 16 -2.1
2.2.20.01. Son of sevenless homolog 1 (two domains) 1dbh Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.8 28 ± 19 -4.2
2.2.20.01. Myosin X 3tfm Rattus norvegicus Endosome 1 0 1.5 ± 2.6 81 ± 5 -3.0
3.1.16.01. Lactococcin-G subunit beta 2jpm Lactococcus lactis Secreted 1 0 6.7 ± 3.3 86 ± 0 -11.2
3.1.05.10. WALP19 - Pro8 peptide 2lco Designed proteins Undefined 1 0 9.0 ± 0.4 85 ± 4 -15.0
2.2.06.01. Beta-lactoglobulin 3nq9 Bos taurus Secreted 1 0 0.5 ± 0.9 89 ± 4 -2.7
2.3.06.01. Butyryl cholinesterase, dimer 5dyy Homo sapiens Secreted 2 0 5.9 ± 0.5 88 ± 2 -11.5
2.2.20.01. Ras-specific guanine nucleotide-releasing factor 2dtc Mus musculus Eukaryo. plasma 1 0 2.7 ± 0.4 64 ± 9 -6.3
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3ld6 Homo sapiens Endoplasm. reticulum 1 0 8.9 ± 0.6 57 ± 2 -16.8
3.1.28.01. Dermatistinctin K 2k9b Phyllomedusa distincta Secreted 1 0 4.6 ± 1.0 90 ± 10 -7.0
2.2.20.01. PH domain of docking protein 2 2d9w Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.2 13 ± 17 -3.5
3.4.02.05. Lichenicidin VK21 A2 2kto Bacillus licheniformis Secreted 1 0 6.6 ± 4.2 75 ± 3 -6.9
3.2.01.07. Peptide PG-990 2n7o Designed proteins Undefined 1 0 7.9 ± 1.6 68 ± 21 -5.6
3.2.05.02. Astexin-4 2n6u Asticcacaulis excentricus Secreted 1 0 2.8 ± 1.1 41 ± 21 -3.8
2.4.16.04. Defensin NsD7, dimer 5vyp Nicotiana suaveolens Secreted 2 0 5.4 ± 0.8 87 ± 7 -7.1
1.2.37.01. ADP-ribosyl cyclase 1 3f6y Homo sapiens Eukaryo. plasma 1 0 2.5 ± 2.4 51 ± 9 -6.3
2.2.02.03. Flavivirin protease NS2B 2wv9 Murray valley encephalitis virus Endoplasm. reticulum 1 0 1.6 ± 2.4 69 ± 8 -4.7
2.1.01.01. Myotoxin 1mc2 Agkistrodon acutus Secreted 1 0 2.4 ± 0.1 80 ± 2 -9.4
3.1.20.01. Conotoxin Ar1446 2m61 Conus araneosus Secreted 1 0 1.8 ± 0.8 82 ± 6 -4.0
2.4.16.11. Tertiapin 1ter Apis mellifera Secreted 1 0 5.1 ± 0.3 80 ± 5 -4.6
3.1.05.15. Guavanin 2 5v1e Designed proteins Undefined 1 0 3.2 ± 1.4 90 ± 10 -6.3
2.2.47.01. Glycoside hydrolase family 9 protein 1wzx Clostridium thermocellum Bact. Gram-pos plas. 1 0 7.4 ± 2.0 77 ± 6 -4.1
3.1.29.01. Cathelicidin LL-37 2k6o Homo sapiens Secreted 1 0 8.1 ± 0.4 86 ± 8 -15.7
3.1.36.01. Clavanin-A 6c41 Styela clava Secreted 1 0 9.1 ± 1.6 84 ± 5 -22.3
3.1.02.08. High affinity copper uptake protein 1, peptide 156-179 2ls4 Homo sapiens Eukaryo. plasma 1 0 4.9 ± 0.7 82 ± 10 -6.5
3.4.05.01. Cyclosporin 1cwa Tolypocladium inflatum Secreted 1 0 10.2 ± 2.5 82 ± 53 -7.2
2.2.12.01. Niemann-Pick type C2 protein 3web Camponotus japonicus Secreted 1 0 5.4 ± 0.3 73 ± 4 -7.6
2.1.21.01. Influenza virus matrix protein M1, structure 1 1aa7 Influenza virus Viral 2 0 2.6 ± 0.8 89 ± 4 -5.6
2.2.34.02. Kappa-theraphotoxin-Scg1a 1la4 Stromatopelma calceatum griseipes Secreted 1 0 4.6 ± 0.4 80 ± 5 -5.9
2.1.02.01. Seed lipoxygenase-B 2iuj Glycine max Eukaryo. plasma 1 0 1.7 ± 3.0 51 ± 15 -4.8
2.2.34.02. Omega-hexatoxin-Hv2a 1g9p Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 3.0 ± 1.4 78 ± 5 -4.0
2.2.34.11. Kalata-B5 2kux Oldenlandia affinis Secreted 1 0 4.1 ± 1.0 61 ± 25 -6.6
2.2.34.02. Beta/kappa-theraphotoxin-Cg2a 6chc Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 2.6 ± 0.4 78 ± 4 -5.0
1.2.32.01. Cytochrome P450 21-hydroxylase, 21A2 4y8w Homo sapiens Endoplasm. reticulum 1 0 7.2 ± 0.7 59 ± 4 -13.4
2.3.06.08. Pancreatic lipase, complex with colipase 1eth Sus scrofa Secreted 2 0 13.6 ± 0.2 90 ± 3 -13.3
2.4.34.01. Type III antifreeze protein nfeAFP11 2lx2 Zoarces elongatus Secreted 1 0 5.3 ± 1.0 53 ± 5 -7.0
1.2.32.01. Cholesterol side-chain cleavage enzyme (P450 11A1) 3mzs Bos taurus Mitochon. inner 1 0 3.2 ± 0.3 33 ± 1 -6.7
2.2.60.01. Matrix protein VP40 1es6 Zaire ebolavirus Viral 1 0 2.1 ± 0.5 80 ± 3 -6.7
3.1.11.02. Extendin-4 1jrj Heloderma suspectum Secreted 1 0 1.7 ± 0.8 79 ± 8 -5.0
2.1.18.01. Annexin 24 1dk5 Capsicum annuum Eukaryo. plasma 1 0 3.5 ± 1.3 76 ± 18 -4.4
2.2.06.02. Der f 13 allergen 2a0a Dermatophagoides farinae (American house dust mite) Secreted 1 0 3.1 ± 1.3 50 ± 6 -3.5
2.1.18.01. Annexin 4mdv Schistosoma mansoni Eukaryo. plasma 1 0 3.7 ± 0.8 77 ± 9 -5.9
2.3.06.06. Triacylglycerol lipase, closed (inactive) state 3tgl Rhizomucor miehei Secreted 1 0 2.7 ± 1.1 39 ± 7 -5.8
2.2.35.01. Pneumolysin, structure 3 5cr8 Streptococcus pneumoniae Secreted 1 0 4.7 ± 1.2 37 ± 6 -9.3
2.2.20.01. Pleckstrin homology domain-containing family B member 2 2dhi Mus musculus Eukaryo. plasma 1 0 0.6 ± 1.5 86 ± 14 -2.8
1.2.54.01. Dihydroorotate dehydrogenase, structure 2 4cq8 Plasmodium falciparum Mitochon. inner 1 0 4.9 ± 0.4 52 ± 1 -12.0
2.4.44.01. Membrane-associated protein VP24, with karyopherin 4u2x Zaire ebolavirus Viral 2 0 4.5 ± 2.1 33 ± 15 -4.3
2.4.16.03. Potassium channel toxin alpha-KTx 3.1 3odv Androctonus mauretanicus mauretanicus (Scorpion) Secreted 1 0 2.6 ± 0.9 84 ± 5 -5.1
2.3.06.05. Carboxylesterase 3cn9 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 3.5 ± 2.1 11 ± 32 -4.1
2.2.20.01. T-lymphoma invasion and metastasis-inducing protein 1, with G-protein RAC2 1foe Mus musculus Eukaryo. plasma 2 0 4.5 ± 1.1 64 ± 7 -6.7
2.3.14.01. Alpha-tocopherol transfer protein, open state 3w68 Mus musculus Golgi 1 0 6.0 ± 0.6 70 ± 2 -13.8
2.4.16.01. Alpha-mammal toxin AaH2 1aho Androctonus australis (Sahara scorpion) Secreted 1 0 1.7 ± 1.0 64 ± 17 -3.4
3.1.28.06. Magainin analogue, MSI-594 2k98 Designed proteins Undefined 1 0 3.2 ± 0.2 86 ± 2 -8.9
2.2.45.01. Pertactin, complex with phage tail protein 2iou Bordetella bronchiseptica Bact. Gram-neg outer 4 0 3.9 ± 1.2 82 ± 2 -8.2
3.1.14.01. Neurokinin B 1p9f Homo sapiens Secreted 1 0 5.8 ± 1.2 89 ± 18 -6.8
2.1.39.01. Viral protein R, full length 1m8l Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 4.7 ± 2.8 64 ± 36 -4.0
2.4.04.01. Beta-hemolysin 3i48 Staphylococcus aureus Secreted 1 0 2.8 ± 0.8 57 ± 5 -5.1
1.1.63.01. Signal peptidase I 3iiq Escherichia coli Bact. Gram-neg inner 2 0 4.3 ± 0.5 57 ± 2 -10.2
2.3.06.01. Acetylcholinesterase 1ea5 Torpedo californica Eukaryo. plasma 1 0 1.8 ± 1.1 34 ± 5 -4.7
2.2.09.05. Peroxisomal targeting signal 2 receptor, comnplex with Pex21p and thiolase 3w15 Saccharomyces cerevisiae Peroxisome 3 0 5.2 ± 1.6 84 ± 7 -5.8
2.4.16.04. Defensin-like protein 1 1gpt Hordeum vulgare Secreted 1 0 3.1 ± 1.6 28 ± 18 -2.0
2.4.24.01. Mandelate racemase/muconate lactonizing enzyme 1wue Enterococcus faecalis Undefined 2 0 4.0 ± 0.3 86 ± 10 -5.5
3.4.03.01. Heat-stable enterotoxin ST-IA/ST-P 1etn Escherichia coli Secreted 1 0 3.0 ± 3.7 33 ± 39 -2.1
2.2.35.01. Pneumolysin, structure 5 5aoe Streptococcus pneumoniae Secreted 1 0 4.5 ± 2.6 36 ± 16 -5.1
3.1.02.09. Peptide (659-711) of platelet endothelial cell adhesion molecule 2ky5 Homo sapiens Eukaryo. plasma 1 0 1.0 ± 3.8 89 ± 3 -3.7
1.2.15.02. Signal recognition particle receptor 1nrj Saccharomyces cerevisiae Endoplasm. reticulum 2 0 3.9 ± 1.4 82 ± 11 -5.5
2.3.06.02. Antigen 85a 1sfr Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 2.8 ± 0.8 27 ± 9 -7.5
2.2.11.01. Perforin 3w57 Psetta maxima Secreted 1 0 3.8 ± 1.2 38 ± 5 -7.8
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1t27 Rattus norvegicus Eukaryo. plasma 1 0 2.3 ± 1.9 12 ± 12 -4.1
3.1.07.02. Peptide of envelope glycoprotein H (625-644) 2lqy Human herpesvirus Endosome 1 0 3.2 ± 0.8 88 ± 5 -10.2
2.2.33.01. Antifungal peptide 2 1p9z Eucommia ulmoides (Hardy rubber tree) Secreted 1 0 3.5 ± 2.0 84 ± 18 -2.9
3.2.10.01. PawS derived peptide 6 2lwv Designed proteins Undefined 1 0 6.8 ± 1.1 69 ± 16 -7.3
2.3.02.01. Phospholipase C-beta isoform 3, complex with Galpha Q, structure 2 4qj3 Homo sapiens Eukaryo. plasma 2 0 3.2 ± 1.7 63 ± 10 -6.2
2.1.29.03. Apolipoprotein C-I, peptide 27-83 1ioj Homo sapiens Secreted 1 0 0.6 ± 1.8 80 ± 16 -2.8
2.1.19.01. Kappa-buthitoxin-Tt2b 2li3 Tityus trivittatus Secreted 1 0 0.8 ± 0.7 40 ± 6 -2.7
2.1.51.01. Protein farnesyltransferase/geranylgeranyltransferase 1jcr