PDB ID or protein name

All proteins in OPM (3809 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
3.1.20.01. Alpha-conotoxin OmIA 2gcz Conus omaria (Omaria cone) Secreted 1 0 3.0 ± 1.5 62 ± 11 -3.7
3.1.21.09. Cytotoxic linear peptide IsCT 1t51 Opisthacanthus madagascariensis Secreted 1 0 4.1 ± 0.6 87 ± 11 -10.5
2.3.01.10. Galactocerebrosidase 3zr5 Mus musculus Lysosome 1 0 5.2 ± 0.6 87 ± 1 -15.3
2.2.04.01. Retinoid isomerohydrolase, conformation 2 4f2z Bos taurus Eukaryo. plasma 1 0 3.7 ± 0.9 56 ± 2 -9.2
1.2.32.01. Cytochrome P450 21-hydroxylase, 21A2 4y8w Homo sapiens Endoplasm. reticulum 1 0 7.2 ± 0.7 59 ± 4 -13.4
2.2.41.01. Beta-defensin 1 1ijv Homo sapiens Secreted 1 0 3.5 ± 1.9 74 ± 17 -5.4
2.2.41.01. Paneth cell-specific alpha-defensin 1 2mxq Equus caballus Secreted 1 0 3.1 ± 0.6 75 ± 5 -7.2
2.1.02.01. Seed lipoxygenase-3 1rrh Glycine max Eukaryo. plasma 1 0 3.8 ± 1.3 84 ± 7 -5.6
2.3.18.01. Carnitine O-acetyltransferase, complex with substrate 2h3u Mus musculus Mitochon. inner 1 0 3.0 ± 1.0 87 ± 3 -5.9
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, mutant 1 2mb1 Zaire ebolavirus Viral 1 0 3.8 ± 1.8 53 ± 34 -4.5
3.1.01.02. Leader peptide of patellamide protein 2kya Prochloron didemni Secreted 1 0 5.8 ± 0.5 86 ± 4 -8.8
1.1.63.01. Type 1 signal peptidase, apo-enzyme 1kn9 Escherichia coli Bact. Gram-neg inner 1 0 3.4 ± 1.4 80 ± 6 -7.8
3.1.25.01. Latarcin-1 (M-zodatoxin-Lt1a) 2pco Lachesana tarabaevi (Spider) Secreted 1 0 10.1 ± 0.8 77 ± 6 -9.4
3.2.09.01. Octreotide 1soc Designed proteins Undefined 1 0 8.9 ± 1.8 77 ± 21 -7.7
2.3.06.07. Lipase, open (active) state 1ex9 Pseudomonas aeruginosa Secreted 1 0 11.0 ± 1.0 52 ± 5 -30.0
2.2.34.01. Conotoxin muOxi-GVIIJ 2n8h Conus geographus (Geography cone) Secreted 1 0 4.0 ± 1.0 43 ± 5 -4.1
2.3.18.01. Choline O-acetyltransferase 1q6x Rattus norvegicus Eukaryo. plasma 1 0 3.6 ± 0.6 75 ± 6 -8.5
1.2.43.01. Envelope glycoprotein, Zika virus, structure 3 5jhm Zika virus Viral 1 0 6.6 ± 2.4 11 ± 8 -4.9
2.1.60.03. Cysteine-rich venom protein 1rc9 Trimeresurus stejnegeri Secreted 1 0 3.9 ± 0.7 73 ± 5 -5.1
2.1.18.01. Annexin VIII 1w3w Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.0 79 ± 9 -6.2
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 3 4jch Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.2 88 ± 1 -6.0
2.4.16.01. Alpha-toxin Cn12 1pe4 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.1 ± 2.3 17 ± 13 -3.1
2.2.43.01. Hypothetical protein SpyM3_0169 1pg6 Streptococcus pyogenes Undefined 1 0 7.6 ± 1.5 57 ± 6 -7.2
3.1.19.01. Antiamoebin I 1joh Emercelliopsis sp. Secreted 1 0 8.1 ± 0.8 82 ± 5 -11.7
3.2.10.01. PawS derived peptide 20 2ndn Zinnia haageana Secreted 1 0 1.8 ± 0.7 83 ± 11 -4.6
2.2.20.01. Pleckstrin homology domain-containing family A member 6 (PLEKHA6) 2d9y Homo sapiens Eukaryo. plasma 1 0 1.0 ± 0.3 67 ± 1 -6.2
2.4.06.01. Steroidogenic acute regulatory protein, mitochondrial 3p0l Homo sapiens Mitochon. outer 1 0 3.0 ± 1.3 76 ± 10 -4.7
2.3.02.02. Phosphatidylinositol-specific phospholipase C 4f2t Staphylococcus aureus Secreted 1 0 4.3 ± 0.5 65 ± 5 -7.8
2.2.20.01. Dynamin-1 1dyn Homo sapiens Eukaryo. plasma 2 0 4.1 ± 1.2 88 ± 15 -9.7
2.3.12.01. Myotubularin-related protein 2, monomer 1zvr Homo sapiens Endosome 1 0 3.1 ± 0.4 89 ± 8 -5.0
3.1.29.01. Cathelicidin-6 2ket Bos taurus Secreted 1 0 7.1 ± 0.7 82 ± 3 -13.6
2.1.07.01. Decaheme cytochrome c MtrF 3pmq Shewanella oneidensis Bact. Gram-neg outer 1 0 3.9 ± 0.9 86 ± 2 -6.2
2.1.01.01. Snake phospholipase A2, group I 1s6b Naja sagittifera Secreted 1 0 3.0 ± 1.1 81 ± 10 -7.5
2.4.34.01. Ice-structuring protein RD3 1c89 Lycodichthys dearborni Secreted 1 0 3.0 ± 1.0 85 ± 9 -8.7
3.1.04.03. Viral protein R, peptide 13-33, different strain 1fi0 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 2.7 ± 1.2 88 ± 8 -8.6
1.2.15.02. Signal recognition particle receptor 1nrj Saccharomyces cerevisiae Endoplasm. reticulum 2 0 3.9 ± 1.4 82 ± 11 -5.5
2.1.20.01. Osteocalcin 4mzz Bos taurus Secreted 1 0 1.8 ± 1.1 43 ± 8 -3.0
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 405-424 1btq Homo sapiens Eukaryo. plasma 1 0 13.6 ± 2.1 67 ± 11 -22.5
3.1.07.02. Juxtamembrane peptide (657-683) of protein gp160 2me1 Human immunodeficiency virus type 1 Endosome 1 0 7.7 ± 3.8 82 ± 1 -15.0
3.1.21.06. Spinigerin 1zrv Pseudacanthotermes spiniger Secreted 1 0 2.1 ± 3.4 77 ± 5 -3.9
3.2.01.07. Peptide PG-989 2n7n Designed proteins Undefined 1 0 6.1 ± 1.4 83 ± 7 -5.5
2.4.01.01. Cholesterol oxidase 1coy Brevibacterium sterolicum Bact. Gram-pos plas. 1 0 4.4 ± 1.1 43 ± 10 -6.8
2.1.03.01. Phospholipase C 1p6d Bacillus cereus Secreted 1 0 2.8 ± 1.0 52 ± 6 -8.4
3.1.15.05. Enterocin K1 5l82 Enterococcus faecium Secreted 1 0 7.0 ± 3.6 27 ± 6 -6.3
1.2.42.01. UDP-2,3-diacylglucosamine hydrolase, lpxH 5k8k Haemophilus influenzae Bact. Gram-neg inner 1 0 9.3 ± 1.8 13 ± 7 -8.7
3.1.04.03. Viral protein R, peptide 34-51 1kzt Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.4 ± 0.6 77 ± 7 -10.3
2.1.01.01. Snake phospholipase A2, group II, B 1jia Agkistrodon halys pallas Secreted 1 0 3.3 ± 0.5 78 ± 4 -11.2
3.2.01.04. Symmetrical θ-defensin, BTD-2 2lye Macaca mulatta Secreted 1 0 0.4 ± 2.9 80 ± 22 -1.5
2.3.16.09. GTP-binding protein YjiA 1nij Escherichia coli Bact. Gram-neg inner 1 0 3.4 ± 0.1 41 ± 1 -6.7
2.2.20.01. PH domain of TAPP2 1v5p Mus musculus Eukaryo. plasma 1 0 1.4 ± 1.3 61 ± 5 -3.7
2.1.33.01. DrrA protein, PtdIns(4) binding domain, from different strain 3l0m Legionella pneumophila Vacuole 1 0 3.7 ± 4.2 44 ± 7 -4.8
3.1.28.01. Dermaseptin-4 2dd6 Phyllomedusa sauvagei (Sauvage's leaf frog) Secreted 1 0 4.2 ± 1.6 76 ± 6 -7.0
2.4.08.01. Eosinophil cationic protein 1h1h Homo sapiens 1 0 3.5 ± 1.0 88 ± 6 -7.3
2.3.06.12. Esterase LipW 3qh4 Mycobacterium marinum Bact. Gram-pos plas. 1 0 2.4 ± 1.2 76 ± 32 -5.0
2.1.01.01. Phospholipase A2 BnSP-7 1pa0 Bothrops neuwiedi pauloensis Secreted 1 0 2.8 ± 1.0 78 ± 10 -6.9
2.3.25.01. Acyloxyacyl hydrolase, structure 1 5w7b Oryctolagus cuniculus Secreted 2 0 8.2 ± 0.8 87 ± 1 -8.8
2.1.58.01. Serine/threonine-protein kinase pelle 1ik7 Drosophila melanogaster Eukaryo. plasma 1 0 1.5 ± 3.7 86 ± 0 -6.8
1.2.32.01. Cytochrome P450 2D6, conformation 2 3tda Homo sapiens Endoplasm. reticulum 1 0 8.0 ± 0.7 35 ± 7 -12.5
2.3.06.08. Pancreatic lipase 1hpl Equus caballus Secreted 1 0 3.8 ± 0.3 80 ± 5 -8.1
3.2.05.03. Bicyclic peptide BI-32169 3njw Streptomyces sp. Secreted 1 0 6.1 ± 0.3 86 ± 3 -9.9
2.2.27.01. C1 domain of unc-13 homolog A 1y8f Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 1.9 16 ± 17 -2.9
2.2.11.01. Synaptotagmin-like protein 4 3fdw Homo sapiens Vesicle 1 0 3.0 ± 2.0 71 ± 17 -3.6
2.2.34.01. Kappa-conotoxin PVIIA 1av3 Conus purpurascens (Purple cone) Secreted 1 0 3.4 ± 1.9 77 ± 7 -3.2
2.1.01.01. Snake phospholipase A2 crotoxin basic chain 2, group II 2qog Crotalus durissus terrificus Secreted 1 0 2.1 ± 1.1 84 ± 8 -7.2
3.4.12.05. Ramoplanin A2 1dsr Actinoplanes sp. Secreted 1 0 6.9 ± 0.4 55 ± 22 -4.7
1.2.32.01. Prostaglandin I2 synthase 3b98 Danio rerio Endoplasm. reticulum 1 0 4.4 ± 1.3 65 ± 6 -4.7
2.2.34.02. Robustoxin 1qdp Atrax robustus Secreted 1 0 1.8 ± 1.9 86 ± 18 -5.0
2.3.06.06. Lipase 3zpx Ustilago maydis Secreted 1 0 5.8 ± 0.8 88 ± 1 -14.0
3.1.07.03. Hemagglutinin, fusion peptide 346-365, G1S 1xop Influenza virus Viral 1 0 6.3 ± 0.5 70 ± 13 -11.0
2.4.16.01. Neurotoxin 1dq7 Buthus tamulus Secreted 1 0 5.9 ± 1.8 88 ± 18 -8.1
2.2.34.06. Ginsentide 2ml7 Panax ginseng Secreted 1 0 7.6 ± 1.1 54 ± 8 -7.7
1.2.33.02. Protoporphyrinogen oxidase 2ivd Myxococcus xanthus Bact. Gram-neg inner 1 0 3.7 ± 0.2 29 ± 2 -8.0
2.4.50.01. Matrix protein, Indiana virus 1lg7 Vesicular stomatitis virus Viral 1 0 2.7 ± 0.4 82 ± 2 -7.3
3.1.14.01. Uperolein 2gfr Uperoleia rugosa (Wrinkled toadlet) Secreted 1 0 6.4 ± 1.2 88 ± 9 -8.2
2.2.05.01. Amicyanin 1id2 Paracoccus versutus Bact. Gram-neg inner 1 0 4.2 ± 1.3 52 ± 8 -4.9
3.1.02.01. Fourth intracellular loop of CB1 cannabinoid receptor 2mz2 Designed proteins Eukaryo. plasma 1 0 6.3 ± 1.2 80 ± 6 -7.4
2.3.06.06. Lipase 2 3o0d Yarrowia lipolytica Secreted 1 0 6.8 ± 2.4 79 ± 26 -9.4
2.2.41.02. Anthopleurin-B 1apf Anthopleura xanthogrammica Secreted 1 0 6.4 ± 1.3 78 ± 19 -7.1
2.3.06.06. Lipase 4l3w Rhizopus chinensis Secreted 1 0 3.2 ± 0.7 31 ± 2 -6.5
2.2.11.01. Multiple C2 and transmembrane domain-containing protein 2 (MCTP2) 2ep6 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.5 7 ± 15 -3.0
2.3.15.02. FAD synthase 2wsi Saccharomyces cerevisiae Mitochon. inner 1 0 3.3 ± 1.7 65 ± 17 -4.0
1.2.43.07. Glycoprotein C, structure 2 5j9h Puumala virus Viral 3 0 4.8 ± 0.3 2 ± 4 -12.9
2.3.01.07. Chitinase B 1h0i Serratia marcescens Secreted 1 0 3.8 ± 1.4 70 ± 12 -5.2
2.2.11.01. Cytosolic phospholipase A2, group IVA 1rlw Homo sapiens Eukaryo. plasma 1 0 6.4 ± 1.9 57 ± 17 -7.8
2.3.14.01. Phosphatidylinositol transfer protein sec14p 1aua Saccharomyces cerevisiae Golgi 1 0 8.8 ± 1.1 75 ± 10 -14.3
3.1.13.01. Proadrenomedullin N-20 terminal peptide 2fly Homo sapiens Secreted 1 0 4.8 ± 4.0 88 ± 2 -7.5
3.1.05.07. Penetratin 1omq Designed proteins Undefined 1 0 3.2 ± 1.0 79 ± 7 -7.4
2.1.12.01. Outer surface protein C 1g5z Borrelia burgdorferi Bact. Gram-neg outer 2 0 3.6 ± 0.6 2 ± 8 -7.0
3.1.15.01. Leucocin A 1cw6 Leuconostoc gelidum Secreted 1 0 3.6 ± 1.1 90 ± 16 -6.2
3.1.11.06. Parathyroid hormone-related peptide, structure 1 1bzg Homo sapiens Secreted 1 0 6.4 ± 2.2 54 ± 18 -6.4
2.3.06.05. Acyl-protein thioesterase 1 1fj2 Homo sapiens Eukaryo. plasma 1 0 9.6 ± 2.0 64 ± 14 -4.7
2.1.21.02. Matrix protein p10, myristoylated, structure 3 5lmy Mason-Pfizer monkey virus Viral 1 0 1.6 ± 1.6 60 ± 5 -4.2
1.2.55.01. Neutral ceramidase, structure 1 2zws Pseudomonas aeruginosa Secreted 1 0 3.1 ± 2.4 77 ± 3 -8.1
1.1.49.01. ATP-dependent zinc metalloprotease FtsH 3kds Thermotoga maritima Bact. Gram-neg inner 6 0 2.2 ± 0.4 90 ± 0 -12.8
2.1.20.01. Coagulation factor IX 1pfx Sus scrofa Eukaryo. plasma 2 0 1.9 ± 6.0 84 ± 10 -3.9
2.4.16.02. Defensin MGD-1 1fjn Mytilus galloprovincialis (Mediterranean mussel) Secreted 1 0 1.5 ± 1.4 43 ± 12 -3.0
2.3.13.05. Putative peroxiredoxin Rv2238c/MT2298 1xvw Mycobacterium tuberculosis Undefined 1 0 4.6 ± 1.0 20 ± 5 -7.0
2.2.27.01. Ras association domain-containing protein 5, C1 domain 1rfh Mus musculus Eukaryo. plasma 1 0 1.4 ± 0.9 16 ± 6 -3.7
2.1.08.01. Cytochrome c6 1ls9 Cladophora glomerata Thylakoid 1 0 4.1 ± 1.0 70 ± 14 -2.9
2.1.62.02. Subtilosin A 1pxq Bacillus subtilis Secreted 1 0 7.6 ± 0.8 86 ± 3 -9.3
2.2.22.01. Hydrophobin NC2, structure 1 4aog Neurospora crassa Secreted 1 0 3.9 ± 1.7 85 ± 7 -4.6
1.2.03.02. T-cell immunoglobulin and mucin domain-containing protein 2 2or7 Mus musculus Eukaryo. plasma 1 0 0.9 ± 0.7 54 ± 6 -3.3
1.2.32.01. Cytochrome P450 2B4, closed state 1 1suo Oryctolagus cuniculus Endoplasm. reticulum 1 0 4.6 ± 1.3 57 ± 4 -14.2
1.2.22.01. Bcl-2-like protein 2 1o0l Homo sapiens Mitochon. outer 1 0 1.7 ± 2.3 86 ± 14 -3.7
2.2.46.01. Low molecular mass 30 kDa lipoprotein 19G1 4iy8 Bombyx mori Secreted 1 0 4.3 ± 1.2 31 ± 8 -4.2
2.2.06.02. Muscle fatty acid binding protein 1hmt Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.6 49 ± 12 -5.0
2.2.26.01. RUN and FYVE domain-containing protein 1 2yw8 Homo sapiens Endosome 1 0 0.7 ± 3.4 48 ± 38 -2.8
3.1.16.01. Lactococcin-G subunit beta 2jpm Lactococcus lactis Secreted 1 0 6.7 ± 3.3 86 ± 0 -11.2
3.2.10.01. PawS derived peptide 11 2lwq Designed proteins Undefined 1 0 10.1 ± 1.4 55 ± 22 -9.5
2.2.06.01. Beta-lactoglobulin 3nq9 Bos taurus Secreted 1 0 0.5 ± 0.9 89 ± 4 -2.7
2.3.06.01. Butyryl cholinesterase, dimer 5dyy Homo sapiens Secreted 2 0 5.9 ± 0.5 88 ± 2 -11.5
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4, complex with GRB10 3m7f Mus musculus Eukaryo. plasma 2 0 2.2 ± 2.0 76 ± 13 -2.7
3.1.28.01. Dermatistinctin K 2k9b Phyllomedusa distincta Secreted 1 0 4.6 ± 1.0 90 ± 10 -7.0
2.4.06.01. Phosphatidylcholine transfer protein 1ln1 Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 53 ± 16 -4.8
3.1.07.02. Juxtamembrane peptide (671-697) of protein gp160 2me4 Human immunodeficiency virus type 1 Endosome 1 0 7.9 ± 2.9 81 ± 4 -14.0
3.4.02.05. Lichenicidin VK21 A2 2kto Bacillus licheniformis Secreted 1 0 6.6 ± 4.2 75 ± 3 -6.9
3.1.05.03. Glycosaminoglycan-binding (KYE) peptide 2ncw Designed proteins Undefined 1 0 5.0 ± 0.4 84 ± 6 -10.1
3.1.02.01. C-terminal helix of MCP-1 receptor 2mlo Homo sapiens Eukaryo. plasma 1 0 6.0 ± 1.6 86 ± 8 -10.1
1.2.38.01. Penicillin-binding protein 2 2olv Staphylococcus aureus Bact. Gram-pos plas. 1 0 3.7 ± 2.0 58 ± 8 -7.3
3.2.05.02. Astexin-4 2n6u Asticcacaulis excentricus Secreted 1 0 2.8 ± 1.1 41 ± 21 -3.8
2.4.16.04. Defensin NsD7, dimer 5vyp Nicotiana suaveolens Secreted 2 0 5.4 ± 0.8 87 ± 7 -7.1
1.2.01.01. Insulin-like growth factor 1 receptor 1p4o Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.0 37 ± 11 -5.1
3.1.07.05. Nonstructural protein 4b, segment 1751-1780 2jxf Hepatitis C virus Endoplasm. reticulum 1 0 5.6 ± 3.6 85 ± 2 -10.6
2.1.01.01. Myotoxin 1mc2 Agkistrodon acutus Secreted 1 0 2.4 ± 0.1 80 ± 2 -9.4
3.1.20.01. Conotoxin Ar1446 2m61 Conus araneosus Secreted 1 0 1.8 ± 0.8 82 ± 6 -4.0
1.1.55.01. Bacterial polysaccharide co-polymerase FepE 3b8n Escherichia coli Bact. Gram-neg inner 9 0 1.6 ± 0.1 1 ± 0 -20.3
2.2.20.01. PH domain of tyrosine-protein kinase BTK 1bwn Homo sapiens Eukaryo. plasma 2 0 15.3 ± 0.5 90 ± 10 -33.3
2.4.16.11. Tertiapin 1ter Apis mellifera Secreted 1 0 5.1 ± 0.3 80 ± 5 -4.6
2.1.61.01. Muramidase Tse3-Tsi3 complex, conformation 1 4m5f Pseudomonas aeruginosa Bact. Gram-neg outer 2 0 3.4 ± 0.2 84 ± 3 -7.8
3.1.29.01. Cathelicidin LL-37 2k6o Homo sapiens Secreted 1 0 8.1 ± 0.4 86 ± 8 -15.7
3.1.36.01. Clavanin-A 6c41 Styela clava Secreted 1 0 9.1 ± 1.6 84 ± 5 -22.3
2.1.56.01. PALS1-associated tight junction protein 1vf6 Homo sapiens Eukaryo. plasma 2 0 5.8 ± 0.4 53 ± 2 -9.4
3.4.05.01. Cyclosporin 1cwa Tolypocladium inflatum Secreted 1 0 10.2 ± 2.5 82 ± 53 -7.2
2.2.12.01. Niemann-Pick type C2 protein 3web Camponotus japonicus Secreted 1 0 5.4 ± 0.3 73 ± 4 -7.6
2.2.20.01. Cytohesin-3 (Grp1) 1fhx Mus musculus Eukaryo. plasma 1 0 15.0 ± 1.2 18 ± 15 -16.4
2.2.11.01. C2A domain of synaptotagmin-5 5h4y Homo sapiens Vesicle 1 0 2.3 ± 2.3 29 ± 11 -4.5
2.2.34.02. Kappa-theraphotoxin-Scg1a 1la4 Stromatopelma calceatum griseipes Secreted 1 0 4.6 ± 0.4 80 ± 5 -5.9
1.2.51.01. Bis(5-adenosyl)-triphosphatase ENPP4 4lqy Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 81 ± 12 -5.5
2.2.34.02. Delta-theraphotoxin-Hm1a 2n6o Heteroscodra maculata Secreted 1 0 4.0 ± 3.4 76 ± 13 -6.2
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 3 4j14 Homo sapiens Endoplasm. reticulum 1 0 3.4 ± 1.4 35 ± 19 -4.0
2.2.34.11. Kalata-B5 2kux Oldenlandia affinis Secreted 1 0 4.1 ± 1.0 61 ± 25 -6.6
2.2.12.01. Ganglioside GM2 activator 2agc Mus musculus Lysosome 1 0 3.2 ± 1.0 54 ± 12 -5.3
1.2.53.01. Squalene synthase, conformation 4 3wek Homo sapiens Endoplasm. reticulum 1 0 0.4 ± 2.5 87 ± 15 -3.2
2.3.06.08. Pancreatic lipase, complex with colipase 1eth Sus scrofa Secreted 2 0 13.6 ± 0.2 90 ± 3 -13.3
2.4.34.01. Type III antifreeze protein nfeAFP11 2lx2 Zoarces elongatus Secreted 1 0 5.3 ± 1.0 53 ± 5 -7.0
2.3.11.01. Ferrochelatase, conformation 1 1hrk Homo sapiens Mitochon. inner 2 0 2.7 ± 0.1 90 ± 0 -9.9
3.1.07.03. Hemagglutinin, fusion peptide 346-365, H1 subtype 2kxa Influenza virus Viral 1 0 10.3 ± 1.9 84 ± 13 -14.5
3.1.11.02. Extendin-4 1jrj Heloderma suspectum Secreted 1 0 1.7 ± 0.8 79 ± 8 -5.0
2.3.15.01. Electron transfer flavoprotein 1efp Paracoccus denitrificans Bact. Gram-neg inner 2 0 4.3 ± 1.1 90 ± 13 -4.8
2.3.12.01. Myotubularin-related protein 1 5c16 Homo sapiens Eukaryo. plasma 1 0 4.8 ± 0.7 70 ± 16 -5.3
2.2.06.02. Der f 13 allergen 2a0a Dermatophagoides farinae (American house dust mite) Secreted 1 0 3.1 ± 1.3 50 ± 6 -3.5
2.2.06.02. Cellular retinoic acid-binding protein 2 1cbs Homo sapiens Nuclear outer 1 0 7.1 ± 1.9 41 ± 13 -5.9
2.3.06.11. Monoglyceride lipase 4zwn Saccharomyces cerevisiae Endoplasm. reticulum 1 0 4.3 ± 1.7 11 ± 17 -7.5
2.3.06.06. Triacylglycerol lipase, closed (inactive) state 3tgl Rhizomucor miehei Secreted 1 0 2.7 ± 1.1 39 ± 7 -5.8
2.2.35.01. Pneumolysin, structure 3 5cr8 Streptococcus pneumoniae Secreted 1 0 4.7 ± 1.2 37 ± 6 -9.3
1.2.32.01. Cytochrome P450 11B2, mitochondrial 4dvq Homo sapiens Mitochon. inner 1 0 4.8 ± 0.6 48 ± 4 -9.1
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 4 4ut9 Dengue virus Viral 1 0 5.5 ± 2.8 31 ± 8 -5.1
2.4.16.03. Potassium channel toxin alpha-KTx 3.1 3odv Androctonus mauretanicus mauretanicus (Scorpion) Secreted 1 0 2.6 ± 0.9 84 ± 5 -5.1
2.1.15.02. ADP-ribosylation factor-binding protein GGA2 1mhq Homo sapiens Golgi 1 0 4.2 ± 1.2 74 ± 5 -4.1
2.4.16.01. Alpha-mammal toxin AaH2 1aho Androctonus australis (Sahara scorpion) Secreted 1 0 1.7 ± 1.0 64 ± 17 -3.4
2.4.20.01. Cysteine protease 3ois Xylella fastidiosa Undefined 1 0 3.2 ± 0.2 80 ± 4 -6.4
2.4.06.01. Second StART domain of Lam4 6bym Saccharomyces cerevisiae Endoplasm. reticulum 2 0 3.0 ± 0.8 85 ± 23 -5.2
3.1.14.01. Neurokinin B 1p9f Homo sapiens Secreted 1 0 5.8 ± 1.2 89 ± 18 -6.8
2.4.04.01. Beta-hemolysin 3i48 Staphylococcus aureus Secreted 1 0 2.8 ± 0.8 57 ± 5 -5.1
2.1.02.01. 8R-Lipoxygenase, central and C-terminal domains 3fg3 Plexaura homomalla Eukaryo. plasma 1 0 5.0 ± 0.6 86 ± 5 -9.3
2.1.14.01. Peroxisomal targeting signal 1 receptor 1fch Homo sapiens Peroxisome 1 0 6.9 ± 1.2 54 ± 3 -6.7
2.4.16.04. Defensin-like protein 1 1gpt Hordeum vulgare Secreted 1 0 3.1 ± 1.6 28 ± 18 -2.0
2.3.13.01. Stringent starvation protein A 3mdk Pseudomonas putida Undefined 2 0 4.8 ± 0.1 89 ± 0 -5.5
3.4.03.01. Heat-stable enterotoxin ST-IA/ST-P 1etn Escherichia coli Secreted 1 0 3.0 ± 3.7 33 ± 39 -2.1
2.2.35.01. Pneumolysin, structure 5 5aoe Streptococcus pneumoniae Secreted 1 0 4.5 ± 2.6 36 ± 16 -5.1
1.1.26.07. STAS domain of anion permease 3oiz Rhodobacter sphaeroides Bact. Gram-neg inner 1 0 3.9 ± 0.4 18 ± 5 -5.4
3.1.02.07. Sodium/hydrogen exchanger 1, TM helices 2kbv Homo sapiens Eukaryo. plasma 1 0 2.7 ± 6.9 74 ± 4 -4.9
1.2.32.01. Cytochrome P450 2D6, conformation 4 4xry Homo sapiens Endoplasm. reticulum 1 0 8.8 ± 3.0 41 ± 2 -15.5
2.3.06.02. Antigen 85a 1sfr Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 2.8 ± 0.8 27 ± 9 -7.5
2.2.11.01. Perforin 3w57 Psetta maxima Secreted 1 0 3.8 ± 1.2 38 ± 5 -7.8
2.2.06.02. Cellular retinol-binding protein II 1crb Rattus norvegicus Eukaryo. plasma 1 0 2.4 ± 1.7 52 ± 19 -5.3
1.2.39.01. Leucyl-cystinyl aminopeptidase, structure 2 5mj6 Homo sapiens Eukaryo. plasma 1 0 1.8 ± 1.4 76 ± 4 -3.5
3.1.07.02. Juxtamembrane peptide (662-683) of protein gp41 2pv6 Human immunodeficiency virus type 1 Endosome 1 0 6.7 ± 0.6 82 ± 2 -13.5
2.2.33.01. Antifungal peptide 2 1p9z Eucommia ulmoides (Hardy rubber tree) Secreted 1 0 3.5 ± 2.0 84 ± 18 -2.9
3.1.05.03. VG16KRKP peptide, structure 1 2mxh Designed proteins Undefined 1 0 2.5 ± 2.4 82 ± 11 -3.2
2.1.29.03. Apolipoprotein C-I, peptide 27-83 1ioj Homo sapiens Secreted 1 0 0.6 ± 1.8 80 ± 16 -2.8
2.1.19.01. Kappa-buthitoxin-Tt2b 2li3 Tityus trivittatus Secreted 1 0 0.8 ± 0.7 40 ± 6 -2.7
2.2.06.02. Fatty acid-binding protein 9 4a60 Homo sapiens Eukaryo. plasma 1 0 3.2 ± 1.1 38 ± 6 -4.6
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3g1q Trypanosoma brucei Endoplasm. reticulum 1 0 8.1 ± 1.5 62 ± 12 -10.8
2.1.25.01. Bacteriocin AS-48 1o82 Enterococcus faecalis Secreted 1 0 4.4 ± 1.1 81 ± 13 -7.0
2.4.51.01. Heme acquisition protein HasA 3ell Pseudomonas aeruginosa Secreted 1 0 3.3 ± 0.4 18 ± 8 -5.5
1.2.32.01. Cytochrome P450 1n97 Thermus thermophilus Bact. Gram-neg inner 1 0 5.2 ± 0.3 43 ± 5 -9.9
1.2.55.01. Neutral ceramidase 4wgk Homo sapiens Eukaryo. plasma 1 0 4.1 ± 0.5 80 ± 2 -10.0
3.1.07.01. Fusion peptide of protein gp41, hybrid sequences 5nvp Human immunodeficiency virus type 1 Endosome 1 0 3.9 ± 2.0 68 ± 6 -8.1
2.4.16.09. S-locus pollen protein 1ugl Brassica campestris (Field mustard) Secreted 1 0 1.3 ± 0.6 51 ± 5 -3.4
2.2.12.01. Lymphocyte antigen 96, structure 2 4g8a Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.3 67 ± 6 -3.8
2.3.19.01. Toxin B 2bvl Clostridium difficile Secreted 1 0 2.0 ± 1.1 24 ± 14 -4.2
3.1.28.04. Antimicrobial peptide AY1C 5ykl Odorrana andersonii Secreted 1 0 8.1 ± 2.8 67 ± 12 -9.5
1.2.04.01. Integrin beta-3/alpha-V complex 3ije Homo sapiens Eukaryo. plasma 2 0 6.1 ± 2.1 13 ± 14 -9.0
2.4.41.01. Hepatitis C virus non-structural protein NS2 (955-1026) 2hd0 Hepatitis C virus Endoplasm. reticulum 2 0 6.7 ± 0.6 85 ± 0 -11.8
2.1.01.02. Phospholipase A2 1poc Apis mellifera Secreted 1 0 4.0 ± 1.6 60 ± 6 -9.5
2.1.44.01. Sublancin-168 2mij Bacillus subtilis Secreted 1 0 4.0 ± 5.0 83 ± 0 -4.2
2.2.20.01. PH domain containing retinal protein 1 2d9v Mus musculus Eukaryo. plasma 1 0 1.3 ± 1.3 58 ± 14 -5.1
2.1.29.02. Apolipoprotein A-II, different conformation 1l6l Homo sapiens Secreted 2 0 3.9 ± 1.2 65 ± 8 -10.6
2.2.35.01. Intermedilysin 1s3r Streptococcus intermedius Secreted 1 0 5.3 ± 2.0 61 ± 16 -5.6
2.2.06.01. Retinol binding protein 4, structure 4 4psq Homo sapiens Secreted 1 0 4.0 ± 4.0 17 ± 17 -5.4
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 1 2xar Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 1.6 69 ± 7 -6.1
2.2.34.06. Gurmarin 1c4e Gymnema sylvestre Secreted 1 0 3.9 ± 2.6 75 ± 16 -4.8
2.2.34.02. S64 4b2v Sicarius dolichocephalus Secreted 1 0 2.5 ± 0.5 71 ± 2 -4.3
2.2.34.02. Omega-hexatoxin-Hv2a 1g9p Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 3.0 ± 1.4 78 ± 5 -4.0
3.1.20.01. Alpha-conotoxin S1 1qmw Conus striatus Secreted 1 0 2.8 ± 2.6 43 ± 17 -2.5
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 1 2gek Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 3.4 ± 2.6 85 ± 5 -5.7
3.1.08.01. Antifreeze protein A 1wfb Pseudopleuronectes americanus Secreted 1 0 2.8 ± 1.0 88 ± 1 -10.1
2.4.20.01. Cathepsin F 1m6d Homo sapiens Lysosome 1 0 4.3 ± 0.8 80 ± 3 -11.7
2.2.04.01. Retinoid isomerohydrolase, conformation 3 4f30 Bos taurus Eukaryo. plasma 1 0 3.4 ± 1.4 61 ± 7 -10.9
2.2.41.01. Beta-defensin 3 1kj6 Homo sapiens Secreted 1 0 2.7 ± 1.3 18 ± 18 -5.1
3.4.10.01. Methanobactin 4oz7 Methylosinus sporium Secreted 1 0 2.5 ± 1.4 86 ± 15 -4.5
2.1.02.01. Seed lipoxygenase-D 2iuk Glycine max Eukaryo. plasma 1 0 3.7 ± 1.7 85 ± 8 -6.2
1.2.32.01. Cholesterol side-chain cleavage enzyme (P450 11A1), complex with adrenodoxin 3n9y Homo sapiens Mitochon. inner 1 0 4.1 ± 0.6 49 ± 5 -6.2
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, mutant 2 2m5f Zaire ebolavirus Viral 1 0 5.7 ± 1.7 29 ± 30 -5.2
2.2.34.02. Kappa-theraphotoxin-Pg1a 2wh9 Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 6.4 ± 1.0 57 ± 6 -9.2
1.2.39.01. Glutamyl aminopeptidase 4kxd Homo sapiens Eukaryo. plasma 1 0 3.3 ± 0.8 77 ± 2 -4.2
2.3.06.07. Lipase 1cvl Chromobacterium viscosum Secreted 1 0 9.9 ± 1.0 53 ± 9 -8.7
2.1.25.05. Aureocin A53 2n8o Staphylococcus aureus Secreted 1 0 0.8 ± 0.4 78 ± 6 -2.6
2.3.18.01. Choline O-acetyltransferase, different conformation 1t1u Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 1.7 73 ± 15 -6.8
2.3.11.01. Ferrochelatase, conformation 2 (with porphyrin bound) 4klr Homo sapiens Mitochon. inner 2 0 1.3 ± 0.0 90 ± 1 -8.4
1.2.43.01. Envelope glycoprotein, Zika virus, structure 4 5lbv Zika virus Viral 1 0 5.7 ± 2.9 31 ± 6 -5.2
2.4.53.01. Resistin 1rfx Mus musculus Secreted 3 0 3.4 ± 1.2 10 ± 6 -8.7
2.1.18.01. Annexin XII 1dm5 Hydra vulgaris Eukaryo. plasma 3 0 2.7 ± 1.0 90 ± 7 -10.2
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 4 3spw Saccharomyces cerevisiae Golgi 1 0 7.3 ± 1.1 60 ± 9 -4.5
2.4.16.01. Beta-insect depressant toxin LqhIT2 2i61 Leiurus quinquestriatus hebraeus Secreted 1 0 4.3 ± 1.6 80 ± 21 -3.7
2.3.10.01. Glycosyltransferase GtfA 1pn3 Amycolatopsis orientalis (Nocardia orientalis) Undefined 1 0 7.2 ± 1.0 80 ± 5 -7.7
1.2.32.01. Cytochrome P450 17A1, structure 2 5uys Homo sapiens Endoplasm. reticulum 1 0 4.5 ± 0.4 41 ± 8 -6.7
3.1.20.01. alpha-conotoxin PNI1 1pen Conus pennaceus Secreted 1 0 5.2 ± 1.7 27 ± 19 -3.8
3.2.10.01. PawS derived peptide 21 2ndm Zinnia haageana Secreted 1 0 1.9 ± 1.2 83 ± 16 -3.7
2.2.20.01. Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 2da0 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 2.5 64 ± 20 -2.5
1.2.22.01. Activator of apoptosis harakiri, cytosolic helix 2l58 Homo sapiens Mitochon. outer 1 0 2.4 ± 4.0 88 ± 0 -8.5
2.2.20.01. Pleckstrin 1pls Homo sapiens Eukaryo. plasma 1 0 3.6 ± 2.0 61 ± 19 -3.8
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-bound 1o7k Homo sapiens Endosome 1 0 15.2 ± 1.7 60 ± 15 -18.4
3.1.28.04. Phylloseptin-2 2jpy Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 5.8 ± 1.3 86 ± 4 -15.2
3.2.01.07. Peptidomimetic TWLKKRRWKKAK-D-Pro-P 2m7j Designed proteins Undefined 1 0 1.0 ± 1.7 75 ± 37 -2.7
3.1.07.09. Membrane fusion protein p15 2mns Baboon orthoreovirus Eukaryo. plasma 1 0 9.3 ± 7.0 86 ± 4 -9.4
1.2.32.01. Cytochrome P450 120a1 2ve4 Synechocystis sp. Thylakoid 1 0 6.3 ± 0.9 47 ± 8 -8.6
2.1.01.01. Snake phospholipase A2, group I, acidic 1 1gp7 Ophiophagus hannah Secreted 1 0 4.6 ± 1.0 84 ± 12 -5.8
2.4.34.01. Ice-structuring protein SP2(HPLC 1) 1ops Zoarces americanus Secreted 1 0 2.4 ± 1.4 60 ± 12 -4.8
2.1.02.01. 9R-lipoxygenase 5ek8 Synechococcus sp. Bact. Gram-neg inner 1 0 4.0 ± 0.7 78 ± 6 -12.2
3.1.04.03. Viral protein R, peptide 52-96, dimer, different strain 1x9v Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.2 ± 0.7 86 ± 4 -8.6
1.2.32.01. Cytochrome P450 2D6, conformation 1 2f9q Homo sapiens Endoplasm. reticulum 1 0 7.0 ± 1.8 29 ± 10 -12.0
2.2.41.01. Neutrophil defensin 3 1dfn Homo sapiens Secreted 2 0 1.4 ± 1.3 87 ± 15 -3.9
2.1.20.01. Coagulation factor X, GLA domain 1iod Bos taurus Secreted 1 0 3.3 ± 0.9 25 ± 15 -5.2
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 436-456 1bts Homo sapiens Eukaryo. plasma 1 0 9.2 ± 0.3 84 ± 2 -14.8
1.1.01.03. Glucagon-like peptide 1 receptor, extracellular domain 5e94 Homo sapiens Eukaryo. plasma 1 0 3.4 ± 10.0 36 ± 6 -7.5
2.2.41.01. Pelovaterin 2jr3 Pelodiscus sinensis (Chinese softshell turtle) Secreted 1 0 3.2 ± 2.3 58 ± 5 -3.5
3.1.05.03. VG16KRKP peptide, structure 2 2n63 Designed proteins Undefined 1 0 2.5 ± 0.3 57 ± 4 -4.0
2.4.02.01. Epoxide Hydrolase 2bng Mycobacterium tuberculosis Bact. Gram-pos plas. 2 0 8.2 ± 0.6 88 ± 4 -24.0
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1t6m Bacillus thuringiensis Secreted 1 0 3.8 ± 1.4 89 ± 13 -4.9
2.3.25.02. GDSL-like lipase 3p94 Parabacteroides distasonis Secreted 1 0 2.0 ± 2.0 68 ± 6 -4.2
1.1.56.01. Inner membrane protein YejM, strain LT2 5i5f Salmonella typhimurium Bact. Gram-neg inner 1 0 3.7 ± 2.4 62 ± 11 -4.9
3.1.02.02. Voltage sensor of calcium-activated potassium channel 2k44 Homo sapiens Eukaryo. plasma 1 0 7.5 ± 3.0 54 ± 4 -9.8
2.4.06.01. Acyl-coenzyme A thioesterase 11 3fo5 Homo sapiens Endoplasm. reticulum 1 0 2.3 ± 1.4 57 ± 7 -3.9
2.1.01.01. Snake phospholipase A2, group II, neutral 1bjj Agkistrodon halys pallas Secreted 1 0 2.6 ± 0.7 86 ± 5 -8.4
2.2.34.11. Kalata-B12 2kvx Oldenlandia affinis Secreted 1 0 4.4 ± 1.2 68 ± 27 -5.6
2.3.31.01. Sorbose-specific phosphotransferase enzyme IIB component 1nrz Klebsiella pneumoniae Bact. Gram-neg inner 1 0 2.1 ± 0.7 83 ± 3 -4.5
2.2.20.02. Disabled homolog 1 1nu2 Mus musculus Eukaryo. plasma 1 0 14.8 ± 1.1 46 ± 12 -17.6
1.2.32.01. Plant cytochrome P450 74A (allene oxide synthase) 3dan Parthenium argentatum Vacuole 1 0 7.5 ± 0.4 64 ± 2 -24.1
3.1.21.01. Cecropin A (1-8) - magainin (1-12) hybrid 1d9j Hyalophora cecropia (Cecropia moth) Secreted 1 0 2.3 ± 0.9 90 ± 10 -6.4
1.2.39.01. Leucyl-cystinyl aminopeptidase, structure 1 5c97 Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.0 76 ± 3 -7.6
2.1.01.01. Phospholipase A2 bothropstoxin-2 2oqd Bothrops jararacussu Secreted 1 0 6.0 ± 0.6 85 ± 4 -7.8
2.3.25.01. Acyloxyacyl hydrolase, structure 2 5w7a Oryctolagus cuniculus Secreted 1 0 4.8 ± 0.8 16 ± 5 -5.1
1.2.03.07. Netrin receptor UNC5B 3g5b Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 2.5 90 ± 14 -8.5
1.2.32.01. Cytochrome P450 2B6, conformation 2 3ua5 Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 1.1 55 ± 3 -12.9
2.1.03.01. Alpha-toxin 1olp Clostridium absonum Secreted 1 0 2.8 ± 1.8 62 ± 11 -6.1
3.2.05.02. Astexin-1, structure 1 2lti Asticcacaulis excentricus Secreted 1 0 2.4 ± 1.0 85 ± 9 -3.6
2.2.27.01. C1 domanin of SH3 and cysteine-rich domain-containing protein 3 2db6 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 0.1 75 ± 0 -4.8
2.2.11.01. Synaptotagmin-7 2d8k Homo sapiens Vesicle 1 0 2.8 ± 1.3 27 ± 16 -6.6
2.2.34.01. Omega-conotoxin MVIIA 1mvi Conus magus Secreted 1 0 4.7 ± 1.9 68 ± 14 -4.0
2.1.01.01. Snake phospholipase A2, ammodytoxin C, group II 3g8h Vipera ammodytes ammodytes Secreted 1 0 4.1 ± 1.1 81 ± 8 -9.7
3.1.11.07. Humanin 1y32 Homo sapiens Secreted 1 0 6.4 ± 3.6 71 ± 8 -9.6
1.2.32.01. Cytochrome P450 2C19 4gqs Homo sapiens Endoplasm. reticulum 1 0 6.4 ± 2.1 71 ± 5 -9.5
2.2.34.02. Huwentoxin-1 1qk6 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.7 ± 1.5 88 ± 11 -5.1
2.3.06.07. Lipase 4gw3 Proteus mirabilis Secreted 1 0 3.7 ± 0.9 43 ± 7 -5.1
2.4.16.01. Toxin VII 1npi Tityus serrulatus Secreted 1 0 4.6 ± 1.5 52 ± 16 -6.7
3.1.13.01. Adrenomedullin 2l7s Homo sapiens Secreted 1 0 2.6 ± 0.7 90 ± 5 -6.7
2.4.07.01. PX domain of C2alpha-PI3 kinase 2ar5 Homo sapiens Eukaryo. plasma 1 0 5.6 ± 0.9 83 ± 17 -3.7
2.1.08.01. Mitochondrial cytochrome c 1hrc Equus caballus Mitochon. inner 1 0 2.1 ± 1.0 80 ± 16 -2.6
2.4.50.01. Matrix protein, New Jersey virus 2w2r Vesicular stomatitis virus Viral 1 0 4.1 ± 0.1 57 ± 1 -10.4
3.1.13.01. Islet amyloid polypeptide, peptide 38-74 2kj7 Rattus norvegicus Secreted 1 0 3.9 ± 4.3 90 ± 4 -4.2
2.2.05.01. Pseudoazurin 1pmy Methylobacterium extorquens Bact. Gram-neg inner 1 0 1.6 ± 1.4 45 ± 13 -4.3
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 3 5fih Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.5 ± 0.6 89 ± 1 -5.3
2.3.06.19. PHB depolymerase PhaZ7, structure 1 2x5x Pseudomonas lemoignei Secreted 1 0 4.1 ± 3.0 54 ± 41 -5.6
2.2.40.01. Neurotoxin III 1ans Anemonia sulcata Secreted 1 0 3.3 ± 1.4 50 ± 15 -4.7
2.3.06.16. Putative hydrolase RPA1511 4psu Rhodopseudomonas palustris Secreted 1 0 7.0 ± 1.2 47 ± 4 -13.0
2.2.11.01. E3 ubiquitin-protein ligase SMURF2 2jqz Homo sapiens Eukaryo. plasma 1 0 4.2 ± 1.8 23 ± 17 -5.6
1.2.33.02. Protoporphyrinogen oxidase 3nks Homo sapiens Mitochon. inner 1 0 4.8 ± 1.0 59 ± 3 -9.6
1.2.43.01. Envelope glycoprotein, Dengue virus type 4 3uaj Dengue virus Viral 1 0 5.6 ± 2.6 17 ± 7 -5.4
2.3.01.04. Hyaluronidase 1fcq Apis mellifera Secreted 1 0 1.9 ± 2.7 36 ± 13 -3.7
2.2.11.01. Protein kinase C alpha, complex with phosphatidyl serine 1dsy Rattus norvegicus Eukaryo. plasma 1 0 0.9 ± 1.5 18 ± 16 -3.0
2.4.06.01. START domain of collagen type IV alpha-3-binding protein 2e3q Homo sapiens Golgi 1 0 4.3 ± 2.0 41 ± 17 -3.7
3.1.13.01. Calcitonin 2jxz Homo sapiens Secreted 1 0 5.5 ± 1.1 72 ± 6 -11.5
3.1.05.08. MSI-594 derived peptide MSI-594-F5A 2l36 Designed proteins Undefined 1 0 6.9 ± 7.0 79 ± 3 -8.3
1.2.26.01. Outer membrane lipoprotein Wza, water-soluble part 2w8h Escherichia coli Bact. Gram-neg outer 8 0 1.6 ± 0.2 1 ± 0 -22.1
3.1.15.01. Sakacin P 1ohm Lactobacillus sake Secreted 1 0 1.8 ± 1.1 90 ± 11 -4.4
3.1.11.06. Parathyroid hormone-related peptide, structure 2 3ffd Homo sapiens Secreted 1 0 2.2 ± 1.5 89 ± 3 -5.1
2.3.10.07. Lipopolysaccharide biosynthesis protein RfaG 2iw1 Escherichia coli Bact. Gram-neg inner 1 0 3.7 ± 3.1 85 ± 8 -6.0
2.3.06.01. Acetylcholinesterase 4ey4 Homo sapiens Eukaryo. plasma 1 0 3.2 ± 0.5 33 ± 2 -8.4
2.1.21.02. Matrix protein p10, myristoylated, structure 4 2mv4 Mason-Pfizer monkey virus Viral 1 0 0.8 ± 0.8 46 ± 6 -3.0
2.4.32.01. Vanadium chloroperoxidase 3bb0 Curvularia inaequalis Secreted 1 0 3.8 ± 0.8 52 ± 6 -5.3
2.1.20.01. Coagulation factor XIV (protein C) in complex with its receptor 1lqv Homo sapiens Eukaryo. plasma 2 0 3.4 ± 3.9 53 ± 14 -5.6
2.4.16.02. Defensin 2nz3 Anopheles gambiae (African malaria mosquito) Secreted 1 0 6.7 ± 1.3 84 ± 10 -7.4
2.3.25.01. Putative platelet activating factor 2hsj Streptococcus pneumoniae Undefined 2 0 7.9 ± 0.7 89 ± 4 -8.5
2.2.27.01. C1 domain of protein kinase C alpha 2eli Homo sapiens Eukaryo. plasma 1 0 2.1 ± 0.4 23 ± 4 -7.4
2.2.05.01. Plastocyanin 9pcy Phaseolus vulgaris Thylakoid 1 0 1.8 ± 1.6 18 ± 19 -1.9
3.2.06.01. Plasmatocyte-spreading peptide PSP1 1b5n Pseudoplusia includens Secreted 1 0 3.1 ± 1.2 87 ± 16 -3.7
2.2.22.01. Hydrophobin NC2, structure 2 4bwh Neurospora crassa Secreted 1 0 2.7 ± 3.1 85 ± 29 -4.5
1.2.03.02. Hepatitis A virus cellular receptor 1 homolog 2or8 Mus musculus Eukaryo. plasma 1 0 4.2 ± 2.4 51 ± 16 -3.9
1.2.32.01. Cytochrome P450 2C8 1pq2 Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 1.8 65 ± 9 -8.6
1.2.40.01. Mitochondria fission 1 protein 1y8m Saccharomyces cerevisiae Mitochon. outer 1 0 5.2 ± 0.6 88 ± 1 -5.2
2.1.01.01. Basic phospholipase A2 PA-11 3v9m Pseudechis australis Secreted 1 0 4.0 ± 0.5 83 ± 2 -10.1
2.2.06.02. Muscle fatty acid binding protein 1bwy Bos taurus Eukaryo. plasma 1 0 4.8 ± 1.3 71 ± 12 -6.6
2.3.06.01. Acetylcholinesterase 5x61 Anopheles gambiae (African malaria mosquito) Eukaryo. plasma 1 0 2.6 ± 1.5 37 ± 4 -4.0
2.4.07.01. Sorting nexin-5 3hpc Rattus norvegicus Endosome 1 0 0.0 ± 2.1 90 ± 8 -2.4
2.2.34.05. Tachystatin-B2 2dcw Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 3.4 ± 0.8 2 ± 6 -10.1
3.2.10.01. PawS derived peptide 4 2lws Designed proteins Undefined 1 0 7.5 ± 1.3 37 ± 13 -5.8
2.2.07.02. Factor H binding protein 1ys5 Neisseria meningitidis Bact. Gram-neg outer 1 0 3.5 ± 2.6 84 ± 5 -5.6
2.2.06.01. Apolipoprotein D 2hzq Homo sapiens Secreted 1 0 4.5 ± 0.9 69 ± 5 -7.8
3.1.29.01. KR-12 from cathelicidin LL-37 2na3 Homo sapiens Secreted 1 0 3.7 ± 0.7 84 ± 8 -8.3
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4 3b7y Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.5 9 ± 6 -4.1
1.2.32.01. Cytochrome P450 1A2 2hi4 Homo sapiens Endoplasm. reticulum 1 0 6.9 ± 1.0 66 ± 9 -16.2
2.1.32.01. Alpha-synuclein 1xq8 Homo sapiens Eukaryo. plasma 1 0 8.7 ± 1.1 87 ± 4 -15.7
2.1.21.02. Matrix protein p10, myristoylated dimer, different strain 5hyb Mouse mammary tumor virus Eukaryo. plasma 2 0 12.9 ± 10.0 73 ± 10 -9.4
3.1.07.01. Fusion peptide of spike glycoprotein (772-787) 2rum Human SARS coronavirus Endosome 1 0 11.1 ± 1.1 57 ± 13 -10.8
3.4.02.05. Lichenicidin VK21 A1 2ktn Bacillus licheniformis Secreted 1 0 7.0 ± 1.5 77 ± 13 -5.9
3.1.05.03. WYHRLSHLHSRLQD 5mxt Designed proteins Undefined 1 0 5.0 ± 0.8 77 ± 10 -6.3
1.1.59.01. Membrane protease specific for a stomatin homolog, dimer 3viv Pyrococcus horikoshii Archaebac. 2 0 4.5 ± 0.4 88 ± 9 -9.5
3.1.04.06. Amyloidogenic peptide (248-286) of prostatic acid phosphatase 2l3h Homo sapiens Eukaryo. plasma 1 0 4.5 ± 2.7 86 ± 0 -4.2
1.2.38.01. Glycosyltransferase MtgA 3hzs Staphylococcus aureus Bact. Gram-pos plas. 1 0 7.0 ± 1.1 54 ± 9 -14.6
2.1.01.01. Phospholipase A2 homolog, taipoxin beta chain 3vbz Oxyuranus scutellatus scutellatus Secreted 1 0 2.8 ± 0.7 87 ± 2 -7.7
3.1.29.01. Cathelicidin-5 2ndc Bos taurus Secreted 1 0 2.1 ± 2.1 82 ± 17 -3.7
1.2.01.01. Macrophage colony-stimulating factor 1 receptor 3bea Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.5 54 ± 19 -4.2
3.1.09.01. ICP47 protein, active domain (1-34) 1qlo Human herpesvirus Endoplasm. reticulum 1 0 8.6 ± 0.8 58 ± 8 -10.2
2.1.01.01. Snake phospholipase A2, group II, hypotensive 1umv Bothrops jararacussu Secreted 1 0 5.1 ± 0.7 87 ± 4 -8.6
3.2.02.02. Chi-conotoxin Ar1248 2m62 Conus araneosus Secreted 1 0 1.9 ± 1.0 78 ± 12 -3.0
1.1.62.01. Diguanylate cyclase/phosphodiesterase 3pjv Pseudomonas fluorescens Bact. Gram-neg inner 5 0 4.6 ± 1.5 79 ± 4 -6.6
2.2.11.01. Protein unc-13 homolog A, C2A domain 2cjs Rattus norvegicus Eukaryo. plasma 1 0 3.5 ± 2.0 47 ± 12 -5.0
2.1.33.01. DrrA protein, PtdIns(4) binding domain, complex with PtdIns(4) 4mxp Legionella pneumophila Vacuole 1 0 2.8 ± 2.6 59 ± 12 -4.5
3.4.04.02. Surfactin 2npv Bacillus subtilis Secreted 1 0 11.3 ± 2.1 55 ± 13 -11.3
2.1.61.01. Muramidase Tse3-Tsi3 complex, conformation 2 4luq Pseudomonas aeruginosa Bact. Gram-neg outer 2 0 2.2 ± 1.4 69 ± 5 -8.2
1.2.18.01. Sortase B 1rz2 Bacillus anthracis Bact. Gram-pos plas. 1 0 3.0 ± 0.6 82 ± 6 -5.8
3.2.01.06. Lactoferricin B, peptide 38-49 1y58 Bos taurus Secreted 1 0 2.9 ± 1.4 86 ± 18 -3.7
2.4.16.03. Potassium channel toxin alpha-KTx 4.2 6atl Tityus serrulatus Secreted 1 0 2.6 ± 1.6 66 ± 16 -3.4
2.1.02.01. Arachidonate 15-lipoxygenase 5med Synechococcus sp. Bact. Gram-neg inner 1 0 3.3 ± 1.6 75 ± 7 -7.4
2.3.16.07. Ras-related protein Rab-9A 1wms Homo sapiens Eukaryo. plasma 1 0 1.9 ± 0.8 48 ± 7 -5.0
2.2.24.01. Vitelline membrane outer protein-I 1vmo Gallus gallus Secreted 1 0 3.0 ± 2.0 51 ± 12 -5.3
2.4.16.12. Actinomycesin 2ru0 Actinomyces sp. Secreted 1 0 3.5 ± 0.7 83 ± 7 -4.1
2.1.45.01. Kinetoplastid membrane protein 11 5y70 Trypanosoma brucei Eukaryo. plasma 1 0 2.5 ± 0.4 53 ± 4 -4.9
2.2.11.01. Synaptotagmin 1, C2A domain 5t0r Mus musculus Vesicle 1 0 2.8 ± 0.8 22 ± 14 -4.2
2.2.34.02. Kappa-sparatoxin-Hv1b 1emx Heteropoda venatoria (Brown huntsman spider) Secreted 1 0 3.4 ± 0.9 57 ± 8 -4.8
1.2.04.01. Integrin alpha-L, cytoplasmic domain (1113-1170) 2k8o Homo sapiens Eukaryo. plasma 1 0 2.2 ± 0.7 65 ± 3 -3.7
2.1.26.01. Colicin-E1 2i88 Escherichia coli Secreted 1 0 1.1 ± 3.3 58 ± 37 -1.7
3.1.11.01. Peptide YY - vitamin B12 conjugate 2na5 Homo sapiens Secreted 1 0 4.5 ± 3.4 87 ± 19 -3.2
2.2.34.11. Violacin 1 2fqa Viola odorata Secreted 1 0 2.4 ± 3.4 70 ± 46 -4.0
2.3.01.01. Glucosylceramidase 1ogs Homo sapiens Lysosome 1 0 4.2 ± 1.1 89 ± 4 -9.0
3.1.02.08. High affinity copper uptake protein 1, peptide 156-179 2ls4 Homo sapiens Eukaryo. plasma 1 0 4.9 ± 0.7 82 ± 10 -6.5
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form 4ors Homo sapiens Endoplasm. reticulum 1 0 2.6 ± 0.8 71 ± 7 -3.7
2.2.30.01. Elafin, complex with elastase from Pig 1fle Homo sapiens Secreted 2 0 4.4 ± 2.0 52 ± 11 -6.3
2.4.16.13 Copsin 2mn5 Coprinopsis cinerea Secreted 1 0 3.0 ± 1.5 59 ± 9 -5.9
3.1.01.06. Protein PB1-F2, mitochondrial targeting peptide (50-87) 2hn8 Influenza virus Mitochon. inner 1 0 5.1 ± 3.8 86 ± 1 -10.9
3.1.11.02. Extendin-4, with extracellular domain of glucagon-like peptide-1 GPCR 3c59 Heloderma suspectum Secreted 2 0 1.9 ± 0.2 64 ± 0 -6.5
2.3.16.01. Shikimate kinase 1e6c Erwinia chrysanthemi Bact. Gram-neg inner 2 0 2.6 ± 1.8 90 ± 12 -5.8
2.2.06.01. Allergen Bos d 2 1bj7 Bos taurus Secreted 1 0 3.1 ± 1.3 50 ± 6 -3.5
2.3.14.01. Yeast Sec14 Homolog Sfh1 (YKL091C) 3b7n Saccharomyces cerevisiae Nuclear outer 1 0 2.9 ± 1.5 65 ± 18 -5.8
2.3.06.06. Triacylglycerol lipase, open (active) state 4tgl Rhizomucor miehei Secreted 1 0 8.8 ± 0.9 64 ± 11 -18.2
3.1.28.02. Neuromedin-C 2n0h Homo sapiens Secreted 1 0 4.1 ± 1.6 82 ± 18 -3.1
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 5 4utc Dengue virus Viral 1 0 6.3 ± 2.4 13 ± 7 -4.2
2.4.29.01. Enterotoxin type A 1dyq Staphylococcus aureus Secreted 1 0 3.9 ± 0.5 82 ± 6 -6.8
2.3.19.02. Histo-blood group ABO system transferase 2rj6 Homo sapiens Golgi 1 0 2.1 ± 1.3 77 ± 3 -7.1
2.4.16.01. Alpha-insect toxin Lqq3 1lqq Leiurus quinquestriatus quinquestriatus Secreted 1 0 0.8 ± 1.0 80 ± 6 -3.3
2.2.55.01. Shewanella peptidase 3nji Shewanella oneidensis Undefined 2 0 4.0 ± 0.9 81 ± 7 -5.6
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 5 4by0 Trypanosoma cruzi Eukaryo. plasma 1 0 4.8 ± 2.6 88 ± 7 -1.6
3.4.08.01. Neurotensin 2oyv Homo sapiens Secreted 1 0 7.3 ± 2.6 67 ± 17 -5.3
2.2.34.07. Asteropsin A 3q8j Asteropus sp. Secreted 1 0 2.8 ± 1.7 75 ± 15 -3.0
3.1.02.16. Peptide 211-263 of YscU protein 2ml9 Yersinia pseudotuberculosis Bact. Gram-neg inner 1 0 2.9 ± 1.8 82 ± 5 -6.6
2.2.14.01. Lactadherin 3bn6 Bos taurus Secreted 1 0 2.8 ± 0.5 11 ± 4 -7.2
2.3.16.04. Dynamin-like protein 2j69 Nostoc punctiforme Bact. Gram-neg inner 1 0 4.0 ± 7.0 15 ± 10 -5.5
2.2.20.01. PH domain of fermitin family homolog 3 5l81 Mus musculus Eukaryo. plasma 1 0 3.8 ± 2.2 59 ± 7 -4.2
2.3.05.03. D-amino-acid oxidase 1ve9 Sus scrofa Peroxisome 2 0 1.9 ± 2.5 88 ± 4 -4.8
2.4.16.04. Defensin NaD1 1mr4 Nicotiana tabacum Secreted 1 0 4.2 ± 1.8 59 ± 11 -3.0
2.2.09.01. Kelch-like protein 7 3ii7 Homo sapiens Undefined 1 0 2.6 ± 1.8 90 ± 16 -6.5
3.4.04.01. Tsushimycin 1w3m Streptomyces pseudogriseolus Secreted 1 0 9.5 ± 2.1 54 ± 24 -8.6
2.2.35.01. Pneumolysin, structure 6 5aof Streptococcus pneumoniae Secreted 1 0 2.9 ± 2.4 33 ± 9 -5.7
1.1.26.07. STAS domain of sulfate permease 4dgh Vibrio cholerae Bact. Gram-neg inner 1 0 4.6 ± 0.6 33 ± 2 -6.2
1.2.30.01. Potassium voltage-gated channel subfamily E member 1 2k21 Homo sapiens Eukaryo. plasma 1 0 12.1 ± 0.4 54 ± 2 -24.7
1.2.39.01. Endoplasmic reticulum aminopeptidase 1, different conformation 2yd0 Homo sapiens Endoplasm. reticulum 1 0 4.1 ± 2.2 59 ± 8 -4.6
2.1.38.01. Anion-specific porin B 2vql Corynebacterium glutamicum Bact. Gram-pos cell wall 1 0 6.2 ± 0.3 83 ± 2 -12.7
2.2.35.01. Streptolysin O 4hsc Streptococcus pyogenes Secreted 1 0 2.8 ± 3.5 15 ± 27 -5.1
2.2.06.02. Cellular retinol-binding protein II 1kqw Danio rerio Eukaryo. plasma 1 0 3.1 ± 1.3 45 ± 13 -4.9
2.1.64.01. AFMP4P 5j5k Aspergillus fumigatus Eukaryo. plasma 1 0 3.9 ± 1.9 73 ± 13 -6.1
3.1.07.02. Juxtamembrane peptide (684-719) of protein gp41 2kzq Hepatitis C virus Endosome 1 0 4.3 ± 3.3 88 ± 0 -9.9
3.2.01.03. Androctonin 1cz6 Androctonus australis (Sahara scorpion) Secreted 1 0 1.5 ± 2.8 89 ± 16 -3.2
3.4.07.01. VG16KRKP peptide 2mwl Designed proteins Undefined 1 0 4.4 ± 1.3 79 ± 12 -3.6
2.1.05.01. Squalene-hopene cyclase 2sqc Alicyclobacillus acidocaldarius Bact. Gram-pos plas. 2 0 7.4 ± 0.5 90 ± 1 -27.8
2.2.41.01. Beta-defensin 2 1fd3 Homo sapiens Secreted 1 0 5.2 ± 1.2 80 ± 12 -9.1
2.1.19.01. Ribosome-inactivating protein luffin P1 2l37 Luffa aegyptiaca Secreted 1 0 1.3 ± 0.9 80 ± 7 -3.3
2.2.06.02. Fatty acid binding protein 6, ileal (Gastrotropin) 3elz Danio rerio Eukaryo. plasma 1 0 1.1 ± 0.9 85 ± 6 -2.4
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 1 2wuz Trypanosoma cruzi Endoplasm. reticulum 1 0 4.0 ± 1.1 75 ± 11 -9.9
2.1.09.01. Major allergen I 1puo Felis catus Secreted 1 0 3.7 ± 0.8 58 ± 6 -7.8
2.4.51.01. Heme acquisition protein HasA, apoprotein 1ybj Serratia marcescens Secreted 1 0 2.8 ± 2.4 33 ± 9 -3.9
2.4.06.04. STAR-related bacterial protein 2d4r Thermus thermophilus Bact. Gram-neg inner 1 0 6.9 ± 2.2 28 ± 6 -7.1
2.2.20.01. Son of sevenless homolog 1 (two domains) 1dbh Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.8 28 ± 19 -4.2
3.1.07.02. Juxtamembrane peptide (659-671) of protein gp160 1lcx Human immunodeficiency virus type 1 Endosome 1 0 4.6 ± 2.6 83 ± 16 -8.0
3.1.29.01. Ovispirin-1 1hu5 Ovis aries Secreted 1 0 5.7 ± 0.5 81 ± 1 -9.2
2.3.19.01. Cytotoxin L 2vkh Clostridium sordellii Secreted 1 0 1.4 ± 2.0 51 ± 17 -4.5
3.4.04.01. Laspartomycin C 5o0z Streptomyces viridochromogenes Secreted 2 0 7.6 ± 7.6 8 ± 7 -6.7
2.2.07.01. Lipocalin BcnB 5ixg Burkholderia cepacia Bact. Gram-neg inner 1 0 2.0 ± 1.0 36 ± 5 -3.9
2.2.20.01. Ras-specific guanine nucleotide-releasing factor 2dtc Mus musculus Eukaryo. plasma 1 0 2.7 ± 0.4 64 ± 9 -6.3
2.2.54.01. Non-structural protein 5A 3fqm Hepatitis C virus Endoplasm. reticulum 1 0 4.9 ± 1.1 77 ± 7 -7.5
2.1.01.03. Prokaryotic phospholipase A2 1kp4 Streptomyces violaceoruber Secreted 1 0 2.4 ± 1.3 42 ± 13 -5.6
3.1.15.05. LsbB 2mlu Lactococcus lactis Secreted 1 0 4.4 ± 4.1 89 ± 2 -6.0
2.2.20.01. PH domain of docking protein 2 2d9w Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.2 13 ± 17 -3.5
2.1.18.01. Annexin I 1hm6 Sus scrofa Vesicle 1 0 2.1 ± 0.9 88 ± 7 -5.6
2.1.29.04. Apolipoprotein C-II 1i5j Homo sapiens Secreted 1 0 4.4 ± 2.3 42 ± 3 -9.9
2.2.35.01. Anthrolysin O 3cqf Bacillus anthracis Secreted 1 0 2.8 ± 1.0 75 ± 1 -5.8
3.1.04.11. HVF18 peptide 5z5x Homo sapiens Secreted 1 0 3.9 ± 3.9 90 ± 5 -5.7
1.2.37.01. ADP-ribosyl cyclase 1 3f6y Homo sapiens Eukaryo. plasma 1 0 2.5 ± 2.4 51 ± 9 -6.3
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 3 3ksw Trypanosoma cruzi Endoplasm. reticulum 1 0 8.0 ± 6.7 61 ± 6 -9.1
2.2.34.08. Agouti-related protein 1mr0 Homo sapiens Secreted 1 0 3.1 ± 2.0 37 ± 18 -5.6
2.2.34.02. U2-agatoxin-Aop1a 2e2s Allagelena opulenta Secreted 1 0 3.5 ± 0.7 45 ± 14 -5.7
2.2.34.02. Beta-hexatoxin-Mg1a 2gx1 Macrothele gigas (Spider) Secreted 1 0 5.6 ± 2.6 51 ± 9 -4.6
3.1.20.01. Alpha-conotoxin EI 1k64 Conus ermineus Secreted 1 0 3.6 ± 1.4 78 ± 19 -3.3
3.2.01.04. Theta-defensin 1 (RTD-1) 1hvz Macaca mulatta Secreted 1 0 0.8 ± 1.0 89 ± 4 -2.9
2.4.18.01. Phospholipase B-like protein 3fgr Mus musculus Lysosome 2 0 6.5 ± 2.4 79 ± 8 -5.3
2.2.41.01. Beta-defensin 7 1e4t Mus musculus Secreted 1 0 3.6 ± 1.4 13 ± 19 -5.2
3.4.10.01. Methanobactin 2xjh Methylosinus trichosporium Secreted 1 0 0.7 ± 0.7 67 ± 7 -2.9
2.1.02.01. Seed lipoxygenase-B 2iuj Glycine max Eukaryo. plasma 1 0 1.7 ± 3.0 51 ± 15 -4.8
1.2.32.01. Cholesterol side-chain cleavage enzyme (P450 11A1) 3mzs Bos taurus Mitochon. inner 1 0 3.2 ± 0.3 33 ± 1 -6.7
2.2.39.01. Beta-cardiotoxin 3plc Ophiophagus hannah Secreted 1 0 4.6 ± 1.1 73 ± 4 -6.7
2.3.05.02. Sulfide-quinone reductase 3sx6 Acidithiobacillus ferrooxidans Bact. Gram-neg inner 1 0 10.6 ± 0.6 70 ± 8 -7.3
3.1.11.02. Gastric inhibitory polypeptide, complex with N-terminal domain of GPCR 2qkh Homo sapiens Secreted 2 0 6.3 ± 3.2 64 ± 23 -5.9
3.1.06.02. Amphipathic alpha-helix of apolipoprotein 2irg Designed proteins Undefined 1 0 6.4 ± 1.7 83 ± 15 -12.1
2.3.06.07. Lipase L1 1ku0 Bacillus stearothermophilus Secreted 1 0 4.0 ± 0.6 23 ± 9 -8.9
2.1.25.05. Lacticin Q 2n8p Lactococcus lactis Secreted 1 0 3.5 ± 0.8 80 ± 6 -4.0
1.2.54.01. Dihydroorotate dehydrogenase, structure 2 4cq8 Plasmodium falciparum Mitochon. inner 1 0 4.9 ± 0.4 52 ± 1 -12.0
1.2.43.01. Envelope glycoprotein, Zika virus, structure 5 5lbs Zika virus Viral 1 0 2.3 ± 2.5 62 ± 5 -4.7
2.4.53.01. Resistin, different conformation 1rgx Mus musculus Secreted 3 0 8.2 ± 1.2 12 ± 6 -12.1
2.1.18.01. Annexin 24 1dk5 Capsicum annuum Eukaryo. plasma 1 0 3.5 ± 1.3 76 ± 18 -4.4
2.1.41.01. Phosphatidylinositol 4-kinase type 2-alpha, structure 2 4pla Homo sapiens Golgi 1 0 1.0 ± 1.7 49 ± 3 -2.8
2.4.16.04. Defensin-like protein 195 1jxc Arabidopsis thaliana Secreted 1 0 4.0 ± 1.5 21 ± 20 -3.9
2.3.28.01. Aldo-keto reductase family 1 member C1 1qwk Caenorhabditis elegans Undefined 1 0 2.8 ± 1.0 66 ± 3 -6.3
2.1.18.01. Annexin 4mdv Schistosoma mansoni Eukaryo. plasma 1 0 3.7 ± 0.8 77 ± 9 -5.9
3.1.20.01. alpha-conotoxin PNIB 1akg Conus pennaceus Secreted 1 0 4.2 ± 1.4 42 ± 19 -5.9
2.2.35.01. Intermedilysin - CD59 receptor complex 5imt Streptococcus intermedius Secreted 4 0 8.3 ± 0.9 10 ± 26 -9.7
2.2.20.01. Pleckstrin homology domain-containing family B member 2 2dhi Mus musculus Eukaryo. plasma 1 0 0.6 ± 1.5 86 ± 14 -2.8
2.3.18.01. Carnitine O-palmitoyltransferase 1, liver isoform, N-terminal domain 2le3 Homo sapiens Mitochon. outer 1 0 3.9 ± 3.7 80 ± 3 -9.3
1.3.25.01. Necrotic enteritis toxin B 4i0n Clostridium perfringens Secreted 1 0 1.6 ± 2.4 38 ± 7 -4.3
2.2.20.01. T-lymphoma invasion and metastasis-inducing protein 1, with G-protein RAC2 1foe Mus musculus Eukaryo. plasma 2 0 4.5 ± 1.1 64 ± 7 -6.7
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens Endosome 1 0 2.4 ± 1.6 88 ± 12 -4.6
3.1.28.04. Gaegurin-4 2g9l Glandirana rugosa (Japanese wrinkled frog) Secreted 1 0 8.9 ± 4.0 71 ± 3 -9.6
3.1.05.11. ALPS-23 peptide 2m0w Designed proteins Undefined 1 0 5.7 ± 0.5 72 ± 6 -9.4
2.3.06.06. Triacylglycerol lipase, closed (inactive) state 1dt5 Humicola lanuginosa Secreted 1 0 5.1 ± 0.9 79 ± 13 -5.9
2.4.34.01. Ice-structuring protein RD1 1ucs Lycodichthys dearborni Secreted 1 0 2.2 ± 1.0 67 ± 9 -5.5
2.1.39.01. Viral protein R, full length 1m8l Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 4.7 ± 2.8 64 ± 36 -4.0
1.2.32.01. Cytochrome P450 2B4, open state 1 2bdm Oryctolagus cuniculus Endoplasm. reticulum 1 0 10.6 ± 1.0 48 ± 15 -16.2
2.2.34.11. Circulin A 1bh4 Chassalia parviflora Secreted 1 0 3.9 ± 1.2 60 ± 18 -6.6
2.1.20.01. Coagulation factor IX, GLA domain 1nl0 Homo sapiens Secreted 1 0 4.1 ± 0.9 38 ± 13 -4.4
2.3.06.01. Acetylcholinesterase 1ea5 Torpedo californica Eukaryo. plasma 1 0 1.8 ± 1.1 34 ± 5 -4.7
2.4.04.01. Inositol polyphosphate 5-phosphatase OCRL-1 4cmn Homo sapiens Endosome 1 0 6.7 ± 1.6 83 ± 2 -9.2
3.1.28.04. Ranatuerin-2csa 2k10 Rana temporaria Secreted 1 0 10.4 ± 1.2 74 ± 5 -14.3
3.2.10.01. PawS derived peptide 10 2nb6 Designed proteins Undefined 1 0 9.9 ± 2.0 48 ± 30 -9.1
3.4.02.04. Cinnamycin 2dde Streptoverticillium griseoverticillatum Secreted 1 0 3.6 ± 1.9 30 ± 24 -5.4
2.3.25.02. Lipolytic protein 3rjt Alicyclobacillus acidocaldarius Secreted 1 0 4.4 ± 4.4 89 ± 1 -6.3
1.1.56.01. Inner membrane protein YejM, strain K12 5i5h Salmonella typhimurium Bact. Gram-neg inner 1 0 1.1 ± 1.6 65 ± 2 -3.6
3.1.02.09. Peptide (659-711) of platelet endothelial cell adhesion molecule 2ky5 Homo sapiens Eukaryo. plasma 1 0 1.0 ± 3.8 89 ± 3 -3.7
1.2.32.01. Cytochrome P450 2B6, conformation 1 3ibd Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 1.0 57 ± 3 -10.8
2.1.01.01. Snake phospholipase A2, group II 1vap Agkistridon piscivorus Secreted 1 0 5.1 ± 0.6 88 ± 5 -10.3
2.1.62.01. Thuricin alpha 2l9x Bacillus cereus Secreted 1 0 7.1 ± 3.2 84 ± 7 -7.8
2.2.25.01. Superoxide dismutase [Cu-Zn] 1oal Photobacterium leiognathi Bact. Gram-neg inner 1 0 2.4 ± 0.9 77 ± 2 -6.8
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1t27 Rattus norvegicus Eukaryo. plasma 1 0 2.3 ± 1.9 12 ± 12 -4.1
2.1.33.01. DrrA protein, PtdIns(4) binding domain 3n6o Legionella pneumophila Vacuole 1 0 5.1 ± 1.4 56 ± 10 -4.9
3.1.21.01. Cecropin B analogue 2igr Hyalophora cecropia (Cecropia moth) Secreted 1 0 5.1 ± 3.6 87 ± 0 -11.3
2.4.43.01. Cell wall anchor protein of the T6SS system 4b62 Pseudomonas aeruginosa Bact. Gram-neg outer 1 0 2.8 ± 2.5 46 ± 36 -4.6
2.3.02.01. Phospholipase C-beta isoform 3, complex with Galpha Q, structure 2 4qj3 Homo sapiens Eukaryo. plasma 2 0 3.2 ± 1.7 63 ± 10 -6.2
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2 2w8d Bacillus subtilis Bact. Gram-pos plas. 1 0 0.0 ± 6.0 83 ± 58 -1.6
2.3.06.08. Pancreatic lipase-related protein 1 2ppl Homo sapiens Secreted 1 0 7.1 ± 0.9 79 ± 6 -10.2
2.3.25.01. Acyloxyacyl hydrolase, structure 1 5w7c Homo sapiens Secreted 2 0 2.6 ± 0.8 83 ± 5 -5.2
2.1.51.01. Protein farnesyltransferase/geranylgeranyltransferase 1jcr Rattus norvegicus Eukaryo. plasma 2 0 3.2 ± 2.3 56 ± 5 -5.6
3.1.07.08. Peptide of outer capsid glycoprotein VP7 (266-326) 2lm7 Rotavirus A Endoplasm. reticulum 1 0 10.2 ± 1.5 76 ± 0 -13.6
1.2.50.01. Equinatoxin II 1iaz Actinia equina Secreted 1 0 3.0 ± 1.2 44 ± 9 -5.1
3.2.05.02. Astexin-1, structure 2 2m37 Asticcacaulis excentricus Secreted 1 0 3.2 ± 1.1 83 ± 13 -5.1
2.2.06.02. Myelin P2 protein 1yiv Equus caballus Eukaryo. plasma 1 0 1.3 ± 1.7 53 ± 11 -4.8
2.2.11.01. C2 domain of otoferlin 3l9b Rattus norvegicus Vesicle 1 0 2.4 ± 5.2 16 ± 33 -3.4
2.2.34.01. Omega-conotoxin GVIA 2cco Conus geographus (Geography cone) Secreted 1 0 4.4 ± 0.9 62 ± 7 -3.1
2.2.06.02. Intestinal fatty acid binding protein, structure 4 2mo5 Homo sapiens Eukaryo. plasma 1 0 1.9 ± 1.3 59 ± 6 -3.4
2.3.19.03. Galactofuranosyl transferase GlfT2 4fix Mycobacterium tuberculosis Bact. Gram-pos plas. 4 0 3.6 ± 0.0 90 ± 0 -24.8
2.1.01.01. Myotoxin II 1y4l Bothrops asper Secreted 1 0 2.8 ± 0.8 76 ± 7 -10.3
2.2.34.02. U1-TRTX-Sp1a toxin 2ll1 Selenotypus plumipes Secreted 1 0 1.9 ± 3.4 50 ± 5 -3.6
2.2.20.01. PH domain of oxysterol-binding protein homolog 3, fused with lysozyme 4iap Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.5 ± 2.3 81 ± 3 -3.6
2.2.34.02. Phrixotoxin 1 1v7f Paraphysa scrofa Secreted 1 0 4.1 ± 1.2 90 ± 16 -6.8
2.3.06.07. Lipase L1, isoform 2 4fmp Bacillus stearothermophilus Secreted 1 0 5.0 ± 1.6 25 ± 12 -8.9
2.4.16.01. Tx10 alpha-like toxin 1kv0 Buthus martensii Secreted 1 0 1.9 ± 1.1 83 ± 11 -4.6
2.1.25.04. Acidocin B 2mwr Lactobacillus acidophilus Secreted 1 0 4.9 ± 1.6 76 ± 0 -8.6
2.1.22.01. Alternative oxidase 3w54 Trypanosoma brucei Mitochon. inner 2 0 9.7 ± 0.3 89 ± 1 -61.2
2.4.50.01. Matrix protein, Indiana virus, complex with mRNA export factor 4owr Vesicular stomatitis virus Viral 1 0 2.1 ± 0.8 65 ± 2 -7.6
3.1.12.01. Sarafotoxin-M 2ldf Atractaspis microlepidota microlepidota Secreted 1 0 2.3 ± 1.5 30 ± 35 -2.1
2.2.05.01. Azurin I 1rkr Alcaligenes xylosoxidans Bact. Gram-neg inner 1 0 1.0 ± 1.0 43 ± 7 -4.3
2.3.06.14. Esterase LipA 3h2g Xanthomonas oryzae Secreted 1 0 5.1 ± 1.7 87 ± 8 -4.9
2.2.31.01. Collagen-binding type II domain of seminal plasma protein PDC-109 1h8p Bos taurus Secreted 2 0 10.5 ± 0.9 87 ± 7 -16.6
2.3.06.12. Sulfolobus shibatae 3wj1 Sulfolobus shibatae Secreted 1 0 3.1 ± 0.7 52 ± 6 -6.3
2.2.11.01. Protein unc-13 homolog A, C2C domain 3kwu Rattus norvegicus Eukaryo. plasma 1 0 3.3 ± 1.9 67 ± 16 -3.6
1.2.43.01. Envelope glycoprotein, chimeric 1k4r Dengue virus Viral 1 0 6.6 ± 2.4 21 ± 12 -4.9
2.3.01.06. Endoglycoceramidase II 2osx Rhodococcus sp. Secreted 1 0 7.9 ± 0.4 68 ± 1 -13.4
2.2.11.01. Synaptotagmin-1 1rsy Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 1.6 24 ± 17 -4.1
2.4.06.01. STAR-related lipid transfer protein 11, apoprotein (open state) 2e3m Homo sapiens Golgi 1 0 3.4 ± 1.1 44 ± 12 -6.1
3.1.13.01. Calcitonin-1 2glg Oncorhynchus keta (Chum salmon) Secreted 1 0 6.1 ± 0.8 84 ± 4 -11.7
3.1.05.09. Histidine-rich peptide LAH4 2kjn Designed proteins Undefined 1 0 10.5 ± 6.3 89 ± 2 -10.2
1.2.32.01. Cytochrome P450 2C9, structure 3 5w0c Homo sapiens Endoplasm. reticulum 1 0 2.5 ± 3.0 43 ± 3 -5.0
3.1.21.08. Moricin 1kv4 Bombyx mori Secreted 1 0 6.1 ± 0.6 77 ± 14 -10.3
2.1.25.02. Enterocin NKR-5-3B 2mp8 Enterococcus faecium Secreted 1 0 4.9 ± 1.9 68 ± 29 -6.4
2.3.06.13. Protein NDRG2 2qmq Mus musculus Eukaryo. plasma 1 0 8.3 ± 2.2 43 ± 14 -9.6
2.3.05.02. Type II NADH:ubiquinone oxidoreductase 5jwa Plasmodium falciparum Mitochon. inner 2 0 7.6 ± 0.0 90 ± 0 -11.3
2.2.52.01. Allene oxide cyclase 2 2brj Arabidopsis thaliana Chloroplast inner 3 0 2.6 ± 0.5 88 ± 5 -9.7
2.4.52.01. Spondin-2 3d34 Homo sapiens Secreted 1 0 6.3 ± 0.7 35 ± 5 -10.4
2.2.06.02. Retinol-binding protein 2 1opb Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 1.4 25 ± 7 -3.6
2.3.06.12. Gibberellin receptor GID1 3ebl Oryza sativa (Rice) Nuclear inner 1 0 5.2 ± 1.5 59 ± 14 -9.1
2.4.16.02. Defensin 2b68 Crassostrea gigas (Pacific oyster) Secreted 1 0 5.8 ± 1.7 28 ± 20 -4.0
1.2.17.03. Syntaxin-1 2xhe Monosiga brevicollis (Choanoflagellate) Undefined 2 0 4.1 ± 2.3 78 ± 3 -5.3
2.2.27.01. C1 domain of protein kinase C theta 2enn Homo sapiens Eukaryo. plasma 1 0 6.2 ± 1.9 89 ± 3 -7.5
2.2.05.01. Plastocyanin 2plt Chlamydomonas reinhardtii Thylakoid 1 0 1.3 ± 1.5 21 ± 18 -2.0
3.2.06.01. Paralytic peptide 1irr Bombyx mori Secreted 1 0 2.2 ± 1.9 74 ± 19 -3.3
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 2 5iqw Pseudomonas aeruginosa Secreted 1 0 1.5 ± 0.2 24 ± 5 -4.8
2.2.12.01. Lymphocyte antigen 96 2z64 Mus musculus Eukaryo. plasma 1 0 3.4 ± 1.1 66 ± 4 -7.0
1.2.32.01. Cytochrome P450 2C9, structure 1 1og5 Homo sapiens Endoplasm. reticulum 1 0 7.6 ± 1.0 79 ± 6 -13.7
1.2.40.01. Mitochondria fission 1 protein, NMR 1pc2 Homo sapiens Mitochon. outer 1 0 8.5 ± 2.5 48 ± 23 -8.0
2.3.06.07. Lipase 3auk Geobacillus sp. Secreted 1 0 5.6 ± 0.8 25 ± 2 -8.5
2.2.06.02. Intestinal fatty acid binding protein, structure 1 1icm Rattus norvegicus Eukaryo. plasma 1 0 3.5 ± 1.5 51 ± 18 -4.3
2.1.64.01. Envelope glycoprotein, ligand-binding domain 1 5e7x Talaromyces marneffei Eukaryo. plasma 1 0 2.7 ± 2.2 55 ± 13 -4.4
2.4.07.01. Sorting nexin-23 (Kinesin-like protein KIF16B) 2v14 Homo sapiens Endosome 1 0 3.3 ± 3.0 72 ± 14 -5.4
2.2.34.05. Tachystatin-B1 2dcv Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 1.8 ± 1.1 5 ± 9 -5.9
3.2.10.01. PawS derived peptide 5 2lwt Designed proteins Undefined 1 0 8.1 ± 2.2 55 ± 21 -5.2
1.1.02.03. PSII-LHCII supercomplex 5xnl Pisum sativum Thylakoid 58 0 29.0 ± 0.4 0 ± 0 -539.7
2.2.39.01. Cardiotoxin-A1 (cytotoxin 1) 2cdx Naja atra Secreted 1 0 2.6 ± 1.4 85 ± 17 -6.9
3.2.05.02. LP2006 5jpl Nocardiopsis alba Secreted 1 0 3.6 ± 1.7 59 ± 12 -4.2
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4-like 2nsq Homo sapiens Eukaryo. plasma 1 0 1.8 ± 1.1 85 ± 5 -3.3
1.2.32.01. Prostacyclin synthase (cytochrome P450 8A1) 3b6h Homo sapiens Endoplasm. reticulum 1 0 5.0 ± 1.6 64 ± 18 -6.3
3.1.07.01. Fusion peptide of spike glycoprotein (1185-1201) 2run Human SARS coronavirus Endosome 1 0 6.8 ± 4.0 74 ± 7 -10.7
3.1.21.04. Oxyopinin-4a 2l3i Oxyopes takobius (Lynx spider) Secreted 1 0 6.2 ± 1.2 71 ± 10 -6.8
3.1.05.03. GLFDIVKKVVGALG 5mxl Designed proteins Undefined 1 0 5.0 ± 0.4 86 ± 6 -7.8
3.1.02.02. S4-S5 linker peptide (532-551) of HERG K+ channel 2le7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.4 69 ± 9 -5.0
2.3.06.10. Platelet-activating factor acetylhydrolase 3d59 Homo sapiens Secreted 1 0 5.5 ± 1.2 87 ± 10 -13.6
2.2.34.02. Beta-theraphotoxin-Ps1a 5we3 Paraphysa scrofa Secreted 1 0 4.4 ± 3.2 86 ± 5 -5.4
1.2.01.01. Focal adhesion kinase 1 2j0k Gallus gallus Eukaryo. plasma 1 0 5.0 ± 2.1 36 ± 2 -4.1
2.1.17.01. Small hydrophilic endoplasmic reticulum-associated protein (Sherp) 2x43 Leishmania major Endoplasm. reticulum 1 0 4.1 ± 0.3 82 ± 2 -9.0
2.1.01.01. Myotoxin 1god Bothrops godmani Secreted 1 0 3.0 ± 0.8 80 ± 8 -7.4
3.2.02.02. Conopeptide CnVA 3zkt Conus consors (Singed cone) Secreted 1 0 7.9 ± 2.9 88 ± 27 -5.2
2.3.16.03. Transducin 1got Bos taurus Eukaryo. plasma 3 0 4.9 ± 1.2 61 ± 8 -7.0
1.1.71.01. Legionalla phosphoinositide phosphatase, SidP 4jza Legionella pneumophila Vacuole 1 0 2.6 ± 1.7 57 ± 7 -5.6
2.2.39.01. Erabutoxin b 3ebx Laticauda semifasciata (Black-banded sea krait) Secreted 1 0 1.9 ± 1.4 47 ± 11 -4.3
2.1.61.01. Muramidase Tse3-Tsi3 complex, conformation 3 3wa5 Pseudomonas aeruginosa Bact. Gram-neg outer 2 0 4.5 ± 1.4 84 ± 7 -4.6
1.2.18.01. Putative sortase 2wts Streptococcus pneumoniae Bact. Gram-pos plas. 1 0 5.1 ± 1.0 20 ± 3 -4.6
3.1.29.02. Indolicidin analogue (cathelicidin-4) 1qx9 Bos taurus Secreted 1 0 6.6 ± 1.9 46 ± 15 -7.7
2.2.30.01. Elafin 6atu Homo sapiens Secreted 1 0 5.6 ± 1.6 77 ± 18 -5.5
2.3.16.07. GTP-binding protein Rheb 1xtq Homo sapiens Eukaryo. plasma 1 0 2.6 ± 0.6 76 ± 20 -5.1
3.2.05.02. Xanthomonin II 2mfv Xanthomonas gardneri Secreted 1 0 4.1 ± 0.9 38 ± 6 -4.4
2.3.14.01. Sec14-like protein 3 4uyb Homo sapiens Vesicle 1 0 1.8 ± 1.8 71 ± 18 -3.3
2.2.34.02. Beta-theraphotoxin-Cj1a 2i1t Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.2 ± 0.7 58 ± 6 -5.8
1.2.04.01. Integrin alpha-M, cytoplasmic helix (1129-1152) 2lke Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.8 73 ± 12 -3.6
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase 4fdo Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 4.3 ± 1.1 67 ± 4 -5.3
2.2.34.11. Cycloviolacin-O14 2gj0 Viola odorata Secreted 1 0 3.6 ± 1.5 85 ± 16 -5.4
3.2.05.02. Acinetodin 5ui6 Acinetobacter gyllenbergii Secreted 1 0 2.4 ± 1.6 70 ± 16 -2.7
2.2.34.11. Leaf cyclotide 2 2kuk Viola hederacea Secreted 1 0 3.4 ± 1.2 83 ± 20 -5.9
2.3.06.04. Palmitoyl protein thioesterase 1 1eh5 Bos taurus Lysosome 1 0 5.3 ± 0.9 59 ± 6 -8.1
2.2.20.01. Fermitin family homolog 2 4f7h Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.4 72 ± 4 -4.2
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form, mutant 4os0 Homo sapiens Endoplasm. reticulum 1 0 2.4 ± 1.0 77 ± 4 -3.1
2.2.30.01. Nawaprin 1udk Naja nigricollis Secreted 1 0 6.3 ± 1.0 81 ± 8 -7.3
2.1.44.01. Bacteriocin ASM1 2mvi Lactobacillus plantarum Secreted 1 0 5.3 ± 1.4 33 ± 5 -4.9
3.1.07.05. Nonstructural protein 4b, segment 1716-1755 2lvg Hepatitis C virus Viral 1 0 6.4 ± 0.7 82 ± 8 -11.4
3.1.11.02. Glucagon-like peptide 1, with extracellular GPCR domain 3iol Homo sapiens Secreted 2 0 2.8 ± 4.0 70 ± 1 -6.7
2.3.16.01. Shikimate kinase 1via Campylobacter jejuni Bact. Gram-neg inner 2 0 3.9 ± 1.4 89 ± 11 -5.0
2.2.06.01. Extracellular fatty acid-binding protein 2kt4 Coturnix coturnix japonica (Japanese quail) Secreted 1 0 3.9 ± 2.9 61 ± 8 -3.4
2.2.14.02. SUN domain-containing protein 2 3unp Homo sapiens Nuclear outer 3 0 2.7 ± 0.1 20 ± 0 -5.3
1.2.32.01. Cytochrome P450 2B4, closed state, mutant 5iut Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.3 ± 0.5 56 ± 2 -13.0
2.3.06.06. Triacylglycerol lipase, open (active) state 1ein Humicola lanuginosa Secreted 1 0 8.1 ± 0.8 63 ± 4 -14.5
3.2.05.02. Chaxapeptin 1 2n5c Streptomyces leeuwenhoekii Secreted 1 0 7.2 ± 1.0 82 ± 9 -8.8
1.2.43.04. Glycoprotein G, structure 2 5i2s Vesicular stomatitis virus Viral 3 0 5.3 ± 0.4 89 ± 1 -10.4
2.3.01.09. Arabinogalactan endo-1,4-beta-galactosidase 1hjq Humicola insolens (Soft-rot fungus) Secreted 1 0 1.8 ± 1.4 86 ± 7 -3.7
1.2.17.01. Vesicle-associated membrane protein complex 2nps Mus musculus Golgi 4 0 5.6 ± 2.2 68 ± 4 -5.6
2.4.16.01. Beta-toxin CsEI 1b3c Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.9 ± 1.2 70 ± 7 -3.9
2.4.29.01. Superantigen-like protein 3r2t Staphylococcus aureus Undefined 1 0 4.2 ± 0.0 79 ± 1 -6.2
3.1.11.04. Orexin-A 1wso Homo sapiens Secreted 1 0 6.4 ± 1.7 72 ± 14 -5.5
2.2.34.06. Inhibitor cystine knot peptide MCh-1 2m2q Momordica charantia Secreted 1 0 6.9 ± 0.7 74 ± 7 -6.3
2.4.06.03. Class 10 plant pathogenesis-related protein 2qim Lupinus luteus Secreted 1 0 3.3 ± 1.4 41 ± 3 -3.1
1.2.41.01. Acyl-CoA-binding protein 2cb8 Homo sapiens Peroxisome 1 0 2.7 ± 2.0 74 ± 29 -5.2
2.4.16.04. Defensin 3psm Pachyrhizus erosus Secreted 1 0 4.1 ± 1.8 32 ± 8 -5.4
2.4.26.01. Putative uncharacterized protein 3nrd Rhizobium meliloti Undefined 2 0 5.8 ± 0.9 86 ± 3 -13.7
1.1.73.01. TrbI protein 2bhv Helicobacter pylori Bact. Gram-neg outer 1 0 3.1 ± 1.3 42 ± 11 -6.4
2.4.03.01. Tubby protein 3c5n Homo sapiens Eukaryo. plasma 1 0 3.4 ± 0.4 75 ± 5 -7.6
3.4.04.01. Daptomycin, Ca-free, different conformation 1t5m Streptomyces roseosporus Secreted 1 0 2.3 ± 1.3 33 ± 6 -7.9
2.4.16.04. Defensin NsD7 5kk4 Nicotiana tabacum Secreted 2 0 3.5 ± 0.7 80 ± 4 -5.6
1.1.26.07. STAS domain of sulfate permease 4dgf Wolinella succinogenes Bact. Gram-neg inner 1 0 2.6 ± 0.5 51 ± 2 -7.0
1.2.39.01. Endoplasmic reticulum aminopeptidase 1 3mdj Homo sapiens Endoplasm. reticulum 1 0 1.9 ± 3.6 63 ± 10 -4.6
2.3.06.02. MPT51/MPB51 antigen 1r88 Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 1.8 ± 1.0 28 ± 26 -3.9
2.1.01.01. Basic phospholipase A2 homolog CTs-R6 4h0s Trimeresurus stejnegeri Secreted 1 0 6.0 ± 1.2 87 ± 4 -9.4
3.1.03.03. Membrane-bound helix of phosphotransferase IIA component 1o53 Escherichia coli Bact. Gram-neg inner 1 0 3.3 ± 1.3 86 ± 15 -7.8
2.2.06.02. Cellular retinol-binding protein III 1ggl Homo sapiens Eukaryo. plasma 1 0 3.3 ± 1.9 53 ± 16 -4.9
2.1.29.06. Perilipin-3 1szi Mus musculus Endosome 1 0 2.4 ± 2.3 61 ± 6 -4.1
3.2.01.03. Gomesin 1kfp Acanthoscurria gomesiana (Tarantula spider) Secreted 1 0 0.5 ± 1.0 75 ± 6 -2.7
3.1.11.02. Glucagon-like peptide-1 receptor agonists 2n08 Designed proteins Undefined 1 0 6.3 ± 1.3 45 ± 10 -5.4
2.2.41.01. Alpha-defensin cryptdin-4 1tv0 Mus musculus Secreted 1 0 2.9 ± 1.4 67 ± 13 -4.5
3.1.28.08. Ocellatin-LB1 5u9v Leptodactylus labyrinthicus Secreted 1 0 4.7 ± 1.4 76 ± 4 -6.6
3.1.04.02. Major prion protein, peptide 110-136 2lbg Homo sapiens Eukaryo. plasma 1 0 5.0 ± 7.0 86 ± 1 -9.3
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3l4d Leishmania infantum Endoplasm. reticulum 1 0 8.4 ± 1.8 66 ± 9 -12.6
3.2.01.01. Arenicin-2 2jni Arenicola marina Secreted 1 0 2.1 ± 1.1 82 ± 15 -5.2
2.4.51.01. Heme acquisition protein HasA 1b2v Serratia marcescens Secreted 1 0 1.9 ± 1.6 18 ± 18 -3.3
2.3.04.01. Sorbitol dehydrogenase 1k2w Rhodobacter sphaeroides Bact. Gram-neg inner 2 0 2.2 ± 0.3 89 ± 1 -4.4
2.2.27.01. Kinase supressor of Ras, Ksr 1kbf Mus musculus Eukaryo. plasma 1 0 1.8 ± 1.0 63 ± 11 -5.4
2.2.34.03. Toxin Ptu1 1i26 Peirates turpis (Assassin bug) Secreted 1 0 2.5 ± 0.9 52 ± 7 -3.6
3.4.07.02. Bradykinin antagonist B-9340 1bdk Designed proteins Undefined 1 0 4.4 ± 0.4 22 ± 8 -5.1
3.1.04.03. Viral protein R, peptide 50-82 1bde Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.8 ± 1.1 89 ± 24 -6.7
2.4.16.01. Beta-insect excitatory toxin BmKIT1 1wwn Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.2 ± 1.1 72 ± 6 -4.4
3.1.16.02. Carnobacteriocin, X component 5ujr Carnobacterium maltaromaticum Secreted 1 0 5.4 ± 3.0 89 ± 13 -11.9
2.2.07.01. Lipocalin BcnA 5ixh Burkholderia cepacia Bact. Gram-neg inner 1 0 1.4 ± 2.6 28 ± 29 -1.7
2.2.20.01. Rho guanine nucleotide exchange factor 9 complex 2dfk Rattus norvegicus Eukaryo. plasma 2 0 2.8 ± 2.7 69 ± 3 -5.0
1.2.32.01. Steroid 21-hydroxylase (P450 C21) 3qz1 Bos taurus Endoplasm. reticulum 1 0 5.9 ± 1.6 72 ± 3 -10.4
2.1.26.01. Colicin A channel-forming domain 1col Escherichia coli Secreted 1 0 1.8 ± 1.0 43 ± 11 -3.2
3.1.28.05. Peptoid analogue of maculatin 2mmj Litoria genimaculata Secreted 1 0 10.0 ± 4.6 73 ± 3 -13.1
2.2.20.01. Oxysterol binding protein-related protein 11 2d9x Homo sapiens Eukaryo. plasma 1 0 1.4 ± 1.7 55 ± 18 -3.1
2.2.18.01. Subunit mu of AP-2 clatrin adaptor complex, open conformation 2xa7 Rattus norvegicus Vesicle 4 0 3.1 ± 2.2 84 ± 14 -5.9
2.1.29.01. Apolipoprotein A-I, alternative structure of C-terminal domain 3r2p Homo sapiens Secreted 2 0 1.7 ± 1.6 87 ± 3 -4.1
2.1.01.01. Snake phospholipase A2, group I, isoform 3 3jql Naja sagittifera Secreted 1 0 6.2 ± 1.0 85 ± 5 -7.0
2.2.34.13. Nemertide alpha-1 toxin 6ena Lineus longissimus Secreted 1 0 4.0 ± 1.6 85 ± 9 -6.8
2.2.53.01. Fas apoptotic inhibitory molecule 1 3mx7 Homo sapiens Eukaryo. plasma 1 0 4.2 ± 1.4 16 ± 13 -7.1
1.2.32.01. Cytochrome P450 2B4, closed state 2 2q6n Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.5 ± 0.4 55 ± 2 -13.0
2.2.34.01. Omega conotoxin SO3 1fyg Conus striatus Secreted 1 0 2.9 ± 1.1 76 ± 18 -3.5
3.2.01.01. Arenicin-1 2jsb Arenicola marina Secreted 1 0 2.4 ± 2.1 80 ± 11 -5.2
2.3.06.11. Monoglyceride lipase MGLL, open conformation 2 6bq0 Homo sapiens Eukaryo. plasma 1 0 8.5 ± 2.0 12 ± 4 -12.6
2.2.34.02. Hybrid atracotoxin 2h1z Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 0.6 ± 2.0 82 ± 20 -1.9
1.1.26.07. STAS domain of prestin 3llo Rattus norvegicus Eukaryo. plasma 1 0 5.4 ± 0.6 68 ± 4 -5.3
3.1.07.01. Fusion peptide (524-539) of ebolavirus glycoprotein GP2 2rlj Zaire ebolavirus Viral 1 0 5.8 ± 1.8 84 ± 6 -6.8
3.1.20.01. Alpha-conotoxin-like EpI 1a0m Conus episcopatus (Bishop's cone) Secreted 1 0 3.3 ± 1.2 58 ± 9 -3.2
2.1.08.01. Cytochrome c552 1a8c Nitrosomonas europaea Bact. Gram-neg inner 1 0 2.7 ± 1.0 80 ± 11 -4.7
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 2 4nc9 Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 4.1 ± 1.1 69 ± 7 -7.9
3.2.01.04. Retrocyclin-2 (HTD-2) 2atg Macaca mulatta Secreted 1 0 2.4 ± 0.6 87 ± 9 -5.6
2.1.24.01. Saposin A (peptide 60-140), conformation in disc 4ddj Homo sapiens Lysosome 1 0 6.4 ± 0.9 89 ± 3 -8.5
2.2.41.01. Beta-defensin 8 1e4r Mus musculus Secreted 1 0 2.8 ± 1.1 74 ± 19 -5.5
3.1.14.01. Tachykinin-4 2moc Homo sapiens Secreted 1 0 4.6 ± 0.6 75 ± 5 -7.7
2.1.18.01. Annexin IV 2zoc Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.1 82 ± 7 -7.6
2.1.20.01. Osteocalcin 1q8h Sus scrofa Secreted 1 0 2.3 ± 1.7 81 ± 17 -4.4
3.1.02.11. Methyl-accepting chemotaxis protein II 2l9g Escherichia coli Bact. Gram-neg inner 1 0 8.1 ± 4.2 75 ± 0 -11.7
3.1.05.02. Self-assembling lipopeptide detergent 3cay Designed proteins Undefined 2 0 14.5 ± 1.3 78 ± 9 -16.4
1.2.32.01. Cytochrome P450 4B1 5t6q Oryctolagus cuniculus Endoplasm. reticulum 1 0 8.8 ± 0.6 38 ± 2 -17.0
2.3.06.07. Lipase L1, isoform 1 1ji3 Bacillus stearothermophilus Secreted 1 0 3.5 ± 1.7 22 ± 10 -8.0
2.4.16.04. Defensin-like protein 32 2mz0 Arabidopsis thaliana Secreted 1 0 2.6 ± 1.4 19 ± 8 -3.4
2.3.09.01. Cytidylyltransferase 3hl4 Rattus norvegicus Eukaryo. plasma 2 0 2.7 ± 4.0 74 ± 8 -3.2
1.2.43.01. Envelope glycoprotein, Zika virus, structure 6 5gzn Zika virus Viral 1 0 5.1 ± 2.6 41 ± 11 -4.9
2.2.37.01. Primary amine oxidase, liver isozyme 1tu5 Bos taurus Secreted 2 0 2.4 ± 1.2 89 ± 0 -6.1
2.1.18.01. Annexin GH1 1n00 Gossypium hirsutum Eukaryo. plasma 1 0 1.5 ± 2.0 70 ± 17 -3.7
2.4.25.01. N-alpha-acetyltransferase 60, structure 1 5hgz Homo sapiens Golgi 1 0 5.7 ± 1.1 41 ± 7 -8.5
2.4.16.01. Toxin BmKaIT1 1omy Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.0 ± 1.3 83 ± 10 -3.8
2.3.28.01. Aldo-keto reductase family 1 member C21 3fjn Mus musculus Undefined 1 0 2.8 ± 1.0 56 ± 3 -5.2
2.1.60.02. Potassium channel blocking domain of matrix metalloproteinase-23 2k72 Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 2.3 77 ± 22 -4.4
3.1.20.01. alpha-conotoxin MII 1mii Conus magus Secreted 1 0 2.7 ± 1.8 45 ± 19 -4.2
2.2.35.01. Intermedilysin - CD59 receptor complex, trapped toxin 5imy Streptococcus intermedius Secreted 2 0 4.1 ± 1.6 63 ± 7 -7.5
2.2.20.01. Pleckstrin homology domain-containing family A member 5 (PLEKHA5) 2dkp Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.9 64 ± 6 -3.9
1.2.35.01. Fatty acid amide hydrolase 1mt5 Rattus norvegicus Endoplasm. reticulum 2 0 11.1 ± 0.2 89 ± 0 -21.9
1.2.19.01. Mitochondrial import receptor subunit TOM20, 51-145, with presequence peptide 1om2 Rattus norvegicus Mitochon. outer 2 0 2.9 ± 2.7 76 ± 7 -4.8
3.1.11.02. Glucagon analog, lipidated 2m5p Homo sapiens Secreted 1 0 5.2 ± 0.6 85 ± 4 -6.0
2.2.20.01. Dual adaptor of phosphotyrosine and 3-phosphoinositides 1fao Homo sapiens Eukaryo. plasma 1 0 2.4 ± 2.0 59 ± 19 -3.9
2.2.06.02. Retinol-binding protein 1 5h9a Homo sapiens Eukaryo. plasma 1 0 3.3 ± 0.9 59 ± 4 -5.7
2.4.07.01. PX domain of sorting nexin GRD19, ligand-bound 1ocu Saccharomyces cerevisiae Endosome 2 0 15.3 ± 0.8 88 ± 6 -34.9
3.1.24.01. Penaeidin-3a 1ueo Litopenaeus vannamei (Whiteleg shrimp) Secreted 1 0 1.3 ± 3.5 89 ± 2 -5.5
2.4.11.01. Crambin, enantiomer 3ue7 Designed proteins Undefined 1 0 3.4 ± 1.7 89 ± 13 -4.6
2.3.06.01. Bile-salt activated lipase, conformation 2 1akn Bos taurus Secreted 1 0 3.8 ± 1.5 77 ± 15 -6.7
2.4.34.01. Ice-structuring protein 4ur4 Zoarces viviparus Secreted 1 0 3.2 ± 4.1 68 ± 2 -5.8
1.2.32.01. Cytochrome P450 2C9, structure 2 1r9o Homo sapiens Endoplasm. reticulum 1 0 4.0 ± 1.1 59 ± 8 -10.1
2.4.16.02. Drosomycin 1myn Drosophila melanogaster Secreted 1 0 4.6 ± 1.2 10 ± 17 -6.0
3.2.09.03. Tyrocidine A 4m6e Bacillus brevis Secreted 1 0 6.8 ± 0.9 56 ± 8 -9.0
2.3.06.01. Acetylcholinesterase 1n5m Mus musculus Eukaryo. plasma 1 0 3.7 ± 1.3 28 ± 6 -6.1
2.4.16.08. Hydramacin-1 2k35 Hydra vulgaris Secreted 1 0 2.0 ± 0.2 87 ± 2 -4.3
3.2.10.01. PawS derived peptide 9 2nb5 Designed proteins Undefined 1 0 5.6 ± 1.3 79 ± 14 -6.5
2.3.16.02. Translocation ATPase SecA 1tf5 Bacillus subtilis Bact. Gram-pos plas. 1 0 2.5 ± 1.1 64 ± 5 -7.0
2.1.29.01. Apolipoprotein A-I 2a01 Homo sapiens Secreted 1 0 4.8 ± 1.2 63 ± 11 -6.5
2.3.25.02. Phospholipase A1 4hyq Streptomyces albidoflavus Secreted 1 0 1.4 ± 1.4 31 ± 7 -3.9
1.2.03.03. Myelin protein P0 3oai Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.2 72 ± 6 -5.8
1.2.32.01. Cholesterol 7-alpha-monooxygenase (P450 7A1) 3dax Homo sapiens Endoplasm. reticulum 1 0 1.8 ± 1.9 69 ± 8 -3.9
2.1.01.01. Myotoxin 1s8i Agkistrodon contortrix laticinctus Secreted 1 0 4.9 ± 0.7 83 ± 5 -10.6
2.1.62.01. Thuricin beta 2la0 Bacillus cereus Secreted 1 0 10.0 ± 2.6 37 ± 7 -8.8
2.3.32.01. UDP-N-acetylmuramate--L-alanine ligase 1p31 Haemophilus influenzae Bact. Gram-neg inner 1 0 4.4 ± 1.8 29 ± 14 -4.6
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1uw5 Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.5 18 ± 16 -5.4
3.1.03.02. Serine/threonine-protein kinase TOR1, FATC domain 2kit