PDB ID or protein name

All proteins in OPM (3809 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
1.1.25.06. Phosphate transporter 4j05 Acanthamoeba culbertsoni Eukaryo. plasma 1 12 30.0 ± 0.5 14 ± 0 -84.2
2.1.43.01. Acanthaporin 2lrd Acanthamoeba culbertsoni Secreted 1 0 4.8 ± 3.0 56 ± 26 -4.9
3.2.01.03. Gomesin 1kfp Acanthoscurria gomesiana (Tarantula spider) Secreted 1 0 0.5 ± 1.0 75 ± 6 -2.7
1.1.01.01. Proton-pumping rhodopsin-2 from algae 3am6 Acetabularia acetabulum Eukaryo. plasma 1 7 31.2 ± 1.6 10 ± 1 -65.4
1.1.01.01. Rhodopsin I 5ax0 Acetabularia acetabulum Eukaryo. plasma 1 7 32.4 ± 2.2 9 ± 1 -66.6
1.1.08.01. F0 ATP synthase 4bem Acetobacterium woodii Bact. Gram-pos plas. 10 22 34.8 ± 1.1 0 ± 0 -102.9
3.1.03.05. Anchor helix of 1,2-diacylglycerol 3-glucosyltransferase 1z2t Acholeplasma laidlawii Bact. Gram-pos plas. 1 0 9.6 ± 1.6 90 ± 4 -13.7
2.3.05.02. Sulfide-quinone reductase 3sx6 Acidithiobacillus ferrooxidans Bact. Gram-neg inner 1 0 10.6 ± 0.6 70 ± 8 -7.3
1.3.06.02. Carbapenem-associated resistance porin CarO3 4fuv Acinetobacter baumannii Bact. Gram-neg outer 1 8 25.0 ± 2.3 3 ± 1 -38.5
1.3.20.01. Outer membrane receptor PiuA 5fp1 Acinetobacter baumannii Bact. Gram-neg outer 1 22 23.6 ± 0.9 4 ± 1 -68.9
1.3.19.01. Porin OccAB1 5dl5 Acinetobacter baumannii Bact. Gram-neg outer 1 18 23.4 ± 1.1 7 ± 0 -62.2
1.3.20.01. Ferric enterobactin receptor PirA 5fr8 Acinetobacter baumannii Bact. Gram-neg outer 1 22 23.4 ± 0.8 1 ± 0 -65.3
2.1.63.01. Lipid A biosynthesis lauroyl acyltransferase 5kn7 Acinetobacter baumannii Bact. Gram-neg outer 1 0 7.4 ± 1.4 66 ± 0 -7.5
1.3.19.01. Porin OccAB2 5dl6 Acinetobacter baumannii Bact. Gram-neg outer 1 18 23.4 ± 1.4 4 ± 1 -59.1
1.3.19.01. Porin OccAB3 5dl7 Acinetobacter baumannii Bact. Gram-neg outer 1 18 23.0 ± 1.2 4 ± 0 -62.1
2.3.06.16. Lipase lip1 4opm Acinetobacter baumannii Secreted 1 0 1.8 ± 1.0 41 ± 3 -4.4
1.3.19.01. Porin OccAB4 5dl8 Acinetobacter baumannii Bact. Gram-neg outer 1 18 21.4 ± 2.3 3 ± 0 -60.7
1.3.06.02. Carbapenem-associated resistance porin CarO1 4rl9 Acinetobacter baumannii Bact. Gram-neg outer 1 8 24.6 ± 1.5 3 ± 1 -38.3
1.1.10.09. Macrolide export permease MacB 5gko Acinetobacter baumannii Bact. Gram-neg inner 2 8 30.2 ± 1.0 0 ± 0 -64.1
1.3.06.02. Carbapenem-associated resistance porin CarO2 4rlb Acinetobacter baumannii Bact. Gram-neg outer 1 8 25.2 ± 1.6 4 ± 2 -33.7
3.2.05.02. Acinetodin 5ui6 Acinetobacter gyllenbergii Secreted 1 0 2.4 ± 1.6 70 ± 16 -2.7
3.1.19.01. Cephaibol A 1ob4 Acremonium tubakii Secreted 1 0 14.1 ± 2.5 58 ± 18 -14.7
3.1.19.01. Cephaibol B 1ob6 Acremonium tubakii Secreted 1 0 15.0 ± 5.0 42 ± 17 -15.3
3.1.19.01. Cephaibol C 1ob7 Acremonium tubakii Secreted 1 0 15.0 ± 2.1 55 ± 21 -15.0
1.2.50.01. Equinatoxin II 1iaz Actinia equina Secreted 1 0 3.0 ± 1.2 44 ± 9 -5.1
1.2.50.01. Fragaceatoxin C, trimer 3zwj Actinia fragacea (Strawberry anemone) Secreted 3 0 2.4 ± 0.2 89 ± 4 -8.4
1.2.50.01. Fragaceatoxin C, complex with lipids 4tsq Actinia fragacea (Strawberry anemone) Secreted 1 0 2.2 ± 0.9 38 ± 3 -15.5
1.2.50.01. Fragaceatoxin C, monomer 3lim Actinia fragacea (Strawberry anemone) Secreted 1 0 2.6 ± 0.8 46 ± 15 -5.0
1.2.50.01. Fragaceatoxin C, transmembrane octamer 4tsy Actinia fragacea (Strawberry anemone) Secreted 8 8 29.8 ± 1.3 0 ± 0 -79.7
2.4.16.12. Actinomycesin 2ru0 Actinomyces sp. Secreted 1 0 3.5 ± 0.7 83 ± 7 -4.1
3.4.02.01. Actagardine, structure in acetonitrile solution 1aj1 Actinoplanes liguriae Secreted 1 0 3.0 ± 1.1 90 ± 11 -5.7
3.4.12.05. Ramoplanin A2 1dsr Actinoplanes sp. Secreted 1 0 6.9 ± 0.4 55 ± 22 -4.7
3.1.21.01. Aedesin 2mmm Aedes aegypti (Yellowfever mosquito) Secreted 1 1 20.8 ± 0.8 11 ± 3 -12.3
2.4.05.01. Uncharacterized protein 3bkr Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.4 ± 6.2 50 ± 73 -1.2
2.4.05.01. Sterol carrier protein 2-like 2 2qzt Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 1.0 ± 2.0 45 ± 12 -3.0
2.4.05.01. Sterol carrier protein 2 1pz4 Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.8 ± 5.0 37 ± 49 -1.3
1.3.25.01. Aerolysin 5jzt Aeromonas hydrophila Secreted 7 14 22.8 ± 3.0 0 ± 0 -59.5
2.1.59.01. AcrH-AopB chaperone-translocator complex 3wxx Aeromonas hydrophila Bact. Gram-neg inner 2 0 3.6 ± 2.2 51 ± 3 -7.4
1.1.12.11. Potassium channel KvAP, sensor domain 1ors Aeropyrum pernix Archaebac. 1 5 31.5 ± 2.2 19 ± 1 -50.3
1.1.12.11. Potassium channel KvAP, sensor domain, NMR model 2kyh Aeropyrum pernix Archaebac. 1 5 28.6 ± 1.4 19 ± 4 -44.6
1.1.12.11. Potassium channel KvAP, complex with Fab 1orq Aeropyrum pernix Archaebac. 4 12 29.3 ± 1.6 0 ± 0 -78.6
1.1.12.11. Potassium channel KvAP 2a0l Aeropyrum pernix Archaebac. 4 12 29.5 ± 1.1 0 ± 0 -100.0
1.1.82.01. 4-hydroxybenzoate octaprenyltransferase 4od5 Aeropyrum pernix Archaebac. 1 9 29.8 ± 0.9 14 ± 1 -63.9
1.1.90.02. CDP-archaeol synthase 5guf Aeropyrum pernix Archaebac. 1 5 28.2 ± 1.4 15 ± 0 -48.6
2.2.34.02. Mu-agatoxin-Aa1a 1eit Agelenopsis aperta Secreted 1 0 1.3 ± 1.5 59 ± 10 -3.1
2.2.34.02. omega-Agatoxin 1agg Agelenopsis aperta Secreted 1 0 2.5 ± 1.4 57 ± 17 -5.0
2.2.34.02. Omega-agatoxin-4A 1oav Agelenopsis aperta Secreted 1 0 4.0 ± 1.1 75 ± 14 -4.0
1.1.10.09. Macrolide export permease MacB 5lil Aggregatibacter actinomycetemcomitans Bact. Gram-neg inner 2 8 31.0 ± 0.6 3 ± 0 -85.7
2.1.01.01. Snake phospholipase A2, group II 1vap Agkistridon piscivorus Secreted 1 0 5.1 ± 0.6 88 ± 5 -10.3
2.1.01.01. Phospholipase A2 homolog 1ppa Agkistridon piscivorus Secreted 1 0 1.2 ± 0.9 85 ± 8 -4.5
2.1.01.01. Myotoxin 1mc2 Agkistrodon acutus Secreted 1 0 2.4 ± 0.1 80 ± 2 -9.4
2.1.01.01. Snake phospholipase A2, acidic, group II 1ijl Agkistrodon acutus Secreted 1 0 4.2 ± 1.2 83 ± 12 -7.5
2.1.01.01. Myotoxin 1s8i Agkistrodon contortrix laticinctus Secreted 1 0 4.9 ± 0.7 83 ± 5 -10.6
2.1.01.01. Snake phospholipase A2, group II, B 1jia Agkistrodon halys pallas Secreted 1 0 3.3 ± 0.5 78 ± 4 -11.2
2.1.01.01. Snake phospholipase A2, group II, neutral 1bjj Agkistrodon halys pallas Secreted 1 0 2.6 ± 0.7 86 ± 5 -8.4
2.1.01.01. Snake phospholipase A2, group II, acidic 1bk9 Agkistrodon halys pallas Secreted 1 0 7.3 ± 0.3 87 ± 3 -11.4
2.2.34.03. Toxin Ado1 1lmr Agriosphodrus dohrni Secreted 1 0 3.1 ± 1.6 60 ± 19 -4.7
1.1.14.01. Aquaporin Z2 3llq Agrobacterium tumefaciens Bact. Gram-neg inner 4 32 29.8 ± 0.6 0 ± 0 -134.5
1.1.13.02. P2X purinoceptor, structure 1 5u1x Ailuropoda melanoleuca Eukaryo. plasma 3 6 30.2 ± 2.2 0 ± 1 -39.0
1.1.13.02. 5u1x » P2X purinoceptor, structure 2 5u2h Ailuropoda melanoleuca Eukaryo. plasma 3 6 25.8 ± 0.2 0 ± 1 -14.8
2.2.05.01. Azurin I 1rkr Alcaligenes xylosoxidans Bact. Gram-neg inner 1 0 1.0 ± 1.0 43 ± 7 -4.3
1.2.47.01. Nickel-cobalt-cadmium resistance protein NccX 4clv Alcaligenes xylosoxidans Bact. Gram-neg inner 1 0 3.1 ± 0.9 83 ± 0 -6.7
1.1.72.02. YdaH transporter 4r0c Alcanivorax borkumensis Bact. Gram-neg inner 2 22 29.8 ± 0.5 0 ± 0 -155.5
2.1.05.01. Squalene-hopene cyclase 2sqc Alicyclobacillus acidocaldarius Bact. Gram-pos plas. 2 0 7.4 ± 0.5 90 ± 1 -27.8
2.3.25.02. Lipolytic protein 3rjt Alicyclobacillus acidocaldarius Secreted 1 0 4.4 ± 4.4 89 ± 1 -6.3
2.3.06.12. Carboxylesterase 2hm7 Alicyclobacillus acidocaldarius Bact. Gram-pos plas. 1 0 5.8 ± 1.7 70 ± 5 -7.7
1.1.12.10. Sodium channel BacNaV 4lto Alkalilimnicola ehrlichei Bact. Gram-neg inner 4 8 30.6 ± 1.1 2 ± 1 -97.3
1.1.12.10. Sodium channel BacNaV, channel neck mutants 5hj8 Alkalilimnicola ehrlichei Bact. Gram-neg inner 4 8 30.6 ± 1.1 0 ± 0 -96.1
2.2.34.02. U2-agatoxin-Aop1a 2e2s Allagelena opulenta Secreted 1 0 3.5 ± 0.7 45 ± 14 -5.7
1.1.12.10. Na(v)Rh voltage-gated sodium channel 4dxw Alpha proteobacterium Bact. Gram-neg inner 4 24 29.2 ± 0.7 4 ± 0 -149.7
3.2.01.01. Alvinellacin 2llr Alvinella pompejana Secreted 1 0 1.6 ± 1.4 90 ± 5 -2.6
3.1.28.02. Alyteserin-1C 2l5r Alytes obstetricans Secreted 1 0 8.7 ± 4.1 81 ± 0 -14.1
2.2.33.01. Antimicrobial peptide 2 1mmc Amaranthus caudatus (Inca-wheat) Secreted 1 0 1.6 ± 1.2 46 ± 9 -3.9
1.1.13.02. Invertebrate P2X receptor 5f1c Amblyomma maculatum Eukaryo. plasma 3 6 31.0 ± 1.4 0 ± 0 -69.4
2.2.06.02. Fatty acid-binding protein 2 2ftb Ambystoma mexicanum (Axolotl) Eukaryo. plasma 1 0 0.6 ± 2.0 77 ± 20 -1.7
2.2.58.01. Cone arrestin 1suj Ambystoma tigrinum (Tiger salamander) Eukaryo. plasma 1 0 1.4 ± 0.8 82 ± 12 -4.7
2.3.10.01. Glycosyltransferase GtfA 1pn3 Amycolatopsis orientalis (Nocardia orientalis) Undefined 1 0 7.2 ± 1.0 80 ± 5 -7.7
2.1.24.01. Saposin-like protein Ac-SLP-1 3s64 Ancylostoma caninum Secreted 1 0 4.2 ± 2.2 53 ± 16 -4.5
2.4.16.01. Alpha-mammal toxin AaH2 1aho Androctonus australis (Sahara scorpion) Secreted 1 0 1.7 ± 1.0 64 ± 17 -3.4
3.2.01.03. Androctonin 1cz6 Androctonus australis (Sahara scorpion) Secreted 1 0 1.5 ± 2.8 89 ± 16 -3.2
2.4.16.03. Potassium channel toxin alpha-KTx 3.1 3odv Androctonus mauretanicus mauretanicus (Scorpion) Secreted 1 0 2.6 ± 0.9 84 ± 5 -5.1
2.2.40.01. Neurotoxin III 1ans Anemonia sulcata Secreted 1 0 3.3 ± 1.4 50 ± 15 -4.7
2.2.41.02. Antihypertensive protein BDS-1 1bds Anemonia sulcata Secreted 1 0 5.6 ± 0.8 83 ± 9 -9.6
2.2.41.02. Sea anemone toxin IA 1atx Anemonia sulcata Secreted 1 0 4.5 ± 1.7 63 ± 12 -6.1
3.1.13.01. Calcitonin 1bku Anguilla japonica (Japanese eel) Secreted 1 0 3.0 ± 0.4 77 ± 3 -8.7
2.2.34.12. Poneritoxin, omega-PONTX-Ae1a 2nbc Anochetus emarginatus Secreted 1 0 1.7 ± 1.8 72 ± 12 -2.5
2.3.13.01. Glutathione transferase GST1-4 3g7j Anopheles dirus Undefined 2 0 3.1 ± 0.3 88 ± 1 -7.6
2.4.16.02. Defensin 2nz3 Anopheles gambiae (African malaria mosquito) Secreted 1 0 6.7 ± 1.3 84 ± 10 -7.4
2.3.06.01. Acetylcholinesterase 5x61 Anopheles gambiae (African malaria mosquito) Eukaryo. plasma 1 0 2.6 ± 1.5 37 ± 4 -4.0
3.1.21.02. Anoplin 2mjq Anoplius samariensis Secreted 1 0 5.6 ± 1.1 85 ± 8 -8.4
2.2.41.02. Toxin APETx1 1wqk Anthopleura elegantissima (Sea anemone) Secreted 1 0 4.0 ± 1.4 32 ± 18 -7.3
2.2.41.02. Toxin APETx2 1wxn Anthopleura elegantissima (Sea anemone) Secreted 1 0 4.9 ± 1.7 33 ± 18 -5.5
2.2.41.02. Anthopleurin-B 1apf Anthopleura xanthogrammica Secreted 1 0 6.4 ± 1.3 78 ± 19 -7.1
2.2.41.02. Anthopleurin-A 1ahl Anthopleura xanthogrammica Secreted 1 0 3.7 ± 1.2 86 ± 11 -7.3
3.1.19.01. Chrysospermin C 1ee7 Apiocrea chrysosperma Secreted 1 0 9.8 ± 2.3 82 ± 12 -12.2
2.4.16.11. Tertiapin 1ter Apis mellifera Secreted 1 0 5.1 ± 0.3 80 ± 5 -4.6
2.1.01.02. Phospholipase A2 1poc Apis mellifera Secreted 1 0 4.0 ± 1.6 60 ± 6 -9.5
2.3.01.04. Hyaluronidase 1fcq Apis mellifera Secreted 1 0 1.9 ± 2.7 36 ± 13 -3.7
3.1.21.03. Melittin, with organometallic fragment 2mw6 Apis mellifera Secreted 1 1 24.2 ± 2.4 6 ± 2 -11.8
3.1.21.03. Melittin 2mlt Apis mellifera Secreted 1 0 15.0 ± 1.0 65 ± 11 -12.0
1.1.12.03. High conductance calcium-activated potassium channel, structure 1 5tj6 Aplysia californica Eukaryo. plasma 4 28 31.8 ± 0.6 0 ± 0 -273.6
1.1.12.03. High conductance calcium-activated potassium channel, structure 2 5tji Aplysia californica Eukaryo. plasma 4 28 31.4 ± 0.6 0 ± 0 -294.2
2.2.34.02. Mu-cyrtautoxin-As1a 2m36 Apomastus schlingeri Secreted 1 0 1.7 ± 1.0 49 ± 35 -3.2
2.2.41.01. Spheniscin-2 (bird defensin) 1ut3 Aptenodytes patagonicus Secreted 1 0 3.6 ± 1.6 44 ± 17 -6.2
1.1.26.01. Leucine transporter LeuT, outward-facing, return state 5jae Aquifex aeolicus Bact. Gram-neg inner 2 24 29.0 ± 0.8 0 ± 0 -143.0
1.1.10.11. O-antigen polysaccharide ABC transporter 6an7 Aquifex aeolicus Bact. Gram-neg inner 2 12 29.8 ± 1.4 4 ± 1 -87.3
1.1.26.01. Leucine transporter LeuT, outward-facing, return state, mutant 5jag Aquifex aeolicus Bact. Gram-neg inner 1 12 26.8 ± 1.1 11 ± 0 -80.7
1.1.116.01. Glycerol-3-phosphate acyltransferase, structure 1 5xj5 Aquifex aeolicus Bact. Gram-neg inner 1 7 28.2 ± 2.0 16 ± 1 -53.7
1.1.116.01. Glycerol-3-phosphate acyltransferase, structure 2 5xj6 Aquifex aeolicus Bact. Gram-neg inner 1 7 26.2 ± 2.0 9 ± 1 -57.4
1.1.26.01. Leucine transporter LeuT, outward-facing conformation, from bicelles 4fxz Aquifex aeolicus Bact. Gram-neg inner 2 24 28.0 ± 0.6 0 ± 0 -144.3
1.1.116.01. Glycerol-3-phosphate acyltransferase, structure 3 5xj7 Aquifex aeolicus Bact. Gram-neg inner 1 7 26.2 ± 1.4 6 ± 3 -56.7
1.1.116.01. Glycerol-3-phosphate acyltransferase, structure 4 5xj8 Aquifex aeolicus Bact. Gram-neg inner 1 7 27.4 ± 1.6 11 ± 2 -56.9
1.1.80.01. Phospho-N-acetylmuramoyl-pentapeptide-transferase, structure 1 4j72 Aquifex aeolicus Bact. Gram-neg inner 2 20 31.4 ± 1.2 0 ± 0 -141.4
2.3.16.10. Tetraacyldisaccharide 4-kinase 4ehx Aquifex aeolicus Bact. Gram-neg inner 1 0 8.0 ± 1.1 69 ± 3 -13.9
1.1.80.01. Phospho-N-acetylmuramoyl-pentapeptide-transferase, structure 2 5ckr Aquifex aeolicus Bact. Gram-neg inner 2 20 30.4 ± 1.1 0 ± 0 -149.3
1.1.116.01. Glycerol-3-phosphate acyltransferase, structure 5 5xj9 Aquifex aeolicus Bact. Gram-neg inner 1 7 0.0 ± 0.0 0 ± 0 0.0
2.3.16.10. Tetraacyldisaccharide 4-kinase, complex with ADP/ATP 4ehy Aquifex aeolicus Bact. Gram-neg inner 1 0 7.9 ± 0.9 71 ± 4 -12.1
1.1.26.01. Leucine transporter LeuT, outward-facing substrate-free conformation 3tt1 Aquifex aeolicus Bact. Gram-neg inner 2 24 28.2 ± 1.2 0 ± 0 -160.8
1.2.38.01. Penicillin-binding protein 1A 2oqo Aquifex aeolicus Bact. Gram-neg inner 1 0 3.0 ± 1.0 40 ± 6 -11.0
1.1.75.01. Sec-independent protein translocase TatC 4b4a Aquifex aeolicus Bact. Gram-neg inner 1 6 30.4 ± 1.2 17 ± 0 -51.7
1.1.26.01. Leucine transporter LeuT, inward-facing conformation 3tt3 Aquifex aeolicus Bact. Gram-neg inner 1 12 27.4 ± 1.6 9 ± 0 -89.1
1.1.26.01. Leucine transporter LeuT, outward-facing substrate-bound conformation 2a65 Aquifex aeolicus Bact. Gram-neg inner 2 28 29.8 ± 0.5 0 ± 0 -157.9
2.3.10.05. 3-Deoxy-D-manno-octulosonic-acid transferase, WaaA 2xci Aquifex aeolicus Bact. Gram-neg outer 1 0 8.3 ± 1.5 72 ± 1 -20.3
2.3.05.02. Sulfide-quinone reductase 3h28 Aquifex aeolicus Bact. Gram-neg inner 3 0 2.4 ± 0.1 90 ± 0 -19.4
1.1.10.03. Type-1 secretion system ABC transporter (HlyB-like) 5l22 Aquifex aeolicus Bact. Gram-neg inner 2 12 33.0 ± 1.4 1 ± 0 -111.8
1.1.25.05. Nitrate transporter NRT1/ PTR, dimer 4oh3 Arabidopsis thaliana Eukaryo. plasma 2 24 29.0 ± 0.9 0 ± 0 -106.0
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 1 2xar Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 1.6 69 ± 7 -6.1
1.1.25.05. Nitrate transporter NRT1/ PTR, structure 1 4cl4 Arabidopsis thaliana Eukaryo. plasma 1 12 31.6 ± 1.6 7 ± 0 -76.5
1.1.02.03. PSII-LHCII supercomplex 5mdx Arabidopsis thaliana Thylakoid 48 122 29.4 ± 0.4 1 ± 0 -609.5
1.1.25.05. Nitrate transporter NRT1/ PTR, structure 2 5a2n Arabidopsis thaliana Eukaryo. plasma 1 12 31.8 ± 1.3 7 ± 1 -84.3
2.4.16.04. Defensin-like protein 195 1jxc Arabidopsis thaliana Secreted 1 0 4.0 ± 1.5 21 ± 20 -3.9
2.2.52.01. Allene oxide cyclase 2 2brj Arabidopsis thaliana Chloroplast inner 3 0 2.6 ± 0.5 88 ± 5 -9.7
2.4.16.04. Defensin-like protein 32 2mz0 Arabidopsis thaliana Secreted 1 0 2.6 ± 1.4 19 ± 8 -3.4
2.3.003.01. Gamma-ketol reductase 5a3v Arabidopsis thaliana Chloroplast inner 1 0 5.0 ± 0.6 89 ± 4 -8.9
2.3.06.12. Gibberellin receptor GID1A 2zsh Arabidopsis thaliana Nuclear inner 1 0 2.6 ± 1.2 89 ± 6 -5.0
1.1.041.02. Bidirectional sugar transporter SWEET13 5xpd Arabidopsis thaliana Eukaryo. plasma 1 7 31.4 ± 1.0 4 ± 1 -73.0
1.1.38.01. MATE protein 14 5y50 Arabidopsis thaliana Eukaryo. plasma 1 12 32.2 ± 1.4 5 ± 2 -74.8
2.1.18.01. Annexin D1 1ycn Arabidopsis thaliana Eukaryo. plasma 1 0 2.3 ± 1.1 78 ± 14 -3.4
2.1.10.01. Accelerated-cell-death 11 apo-protein 4nt1 Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 2.0 85 ± 7 -5.4
2.1.04.01. Alpha-dioxygenase 1 4hhr Arabidopsis thaliana Endoplasm. reticulum 1 0 10.8 ± 0.1 68 ± 2 -31.4
3.1.03.08. Lipid interacting helix (227-245) of digalactosyldiacylglycerol synthase 2l7c Arabidopsis thaliana Chloroplast outer 1 0 3.3 ± 3.6 88 ± 1 -6.0
2.1.10.01. Accelerated-cell-death 11 protein, complex with lipid 4nti Arabidopsis thaliana Eukaryo. plasma 1 0 5.7 ± 0.5 80 ± 2 -10.7
1.1.09.01. Plasma membrane ATPase 2, E1-ATP state 5ksd Arabidopsis thaliana Eukaryo. plasma 1 10 30.8 ± 1.2 4 ± 1 -59.3
1.1.06.02. Ascorbate-dependent oxidoreductase 4o6y Arabidopsis thaliana Eukaryo. plasma 2 12 31.0 ± 1.3 1 ± 0 -97.6
1.2.32.01. Plant cytochrome P450 74A (allene oxide synthase) 3dsk Arabidopsis thaliana Thylakoid 1 0 5.7 ± 0.5 67 ± 3 -20.0
1.1.12.08. Two pore calcium channel TPC1 5dqq Arabidopsis thaliana Vacuole 2 24 29.8 ± 0.5 0 ± 0 -188.0
1.1.02.02. Photosystem I of plants 4xk8 Arabidopsis thaliana Thylakoid 13 45 29.8 ± 0.5 0 ± 0 -319.6
2.2.11.01. C2 domain of abscisic acid-related protein CAR1 5a50 Arabidopsis thaliana Eukaryo. plasma 1 0 3.4 ± 1.2 79 ± 4 -6.3
1.1.26.08. Boron transporter 1 5l25 Arabidopsis thaliana Eukaryo. plasma 2 28 30.8 ± 0.5 0 ± 0 -109.6
1.1.14.01. Aquaporin TIP2-1 5i32 Arabidopsis thaliana Vacuole 4 24 30.0 ± 0.8 0 ± 0 -154.0
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 2 4axd Arabidopsis thaliana Eukaryo. plasma 1 0 1.5 ± 0.1 88 ± 4 -4.0
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 3 4axc Arabidopsis thaliana Eukaryo. plasma 1 0 3.2 ± 2.3 68 ± 15 -4.5
2.2.11.01. C2 domain of abscisic acid-related protein CAR4 5a52 Arabidopsis thaliana Eukaryo. plasma 2 0 3.9 ± 0.7 82 ± 11 -6.6
1.1.14.01. Aquaporin AqpM 3ne2 Archaeoglobus fulgidus Archaebac. 4 24 31.2 ± 1.3 0 ± 0 -143.5
1.1.84.01. Bifunctional IPC transferase and DIPP synthase 4mnd Archaeoglobus fulgidus Archaebac. 2 12 30.2 ± 1.0 0 ± 0 -86.4
1.1.17.01. Ammonium transporter Amt-1 2b2f Archaeoglobus fulgidus Archaebac. 3 33 28.9 ± 0.7 0 ± 0 -152.5
1.1.09.01. Copper efflux ATPase, CopA 3j08 Archaeoglobus fulgidus Archaebac. 2 16 27.6 ± 0.8 0 ± 0 -72.3
1.1.64.01. H+/Ca2+ exchanger 4kpp Archaeoglobus fulgidus Archaebac. 1 12 29.8 ± 1.4 5 ± 0 -92.3
1.1.82.01. Bacteriochlorophyll synthase 4tq4 Archaeoglobus fulgidus Archaebac. 1 9 29.2 ± 1.5 14 ± 1 -73.5
1.1.10.02. Molybdate transporter ModBC, open state 2onk Archaeoglobus fulgidus Archaebac. 2 12 32.0 ± 1.7 0 ± 1 -100.7
2.3.06.07. Tentative lipase 2zyr Archaeoglobus fulgidus Secreted 1 0 3.0 ± 1.0 57 ± 8 -7.5
1.1.52.01. Transmembrane oligosaccharyl transferase 3wak Archaeoglobus fulgidus Archaebac. 1 13 29.8 ± 0.6 12 ± 0 -100.8
2.3.06.12. Carboxylesterase (EstA) 1jji Archaeoglobus fulgidus Archaebac. 1 0 2.8 ± 1.0 56 ± 22 -4.8
1.1.101.01. Cytochrome C-type biogenesis protein (CcdA) 2n4x Archaeoglobus fulgidus Archaebac. 1 8 29.0 ± 2.0 10 ± 10 -38.7
2.4.05.01. Uncharacterized protein 3cnu Archaeoglobus fulgidus Archaebac. 1 0 7.6 ± 1.7 69 ± 20 -7.0
1.1.09.01. Copper efflux ATPase, CopA, alternative conformation 3j09 Archaeoglobus fulgidus Archaebac. 2 16 27.0 ± 0.1 1 ± 0 -23.5
1.1.84.01. CDP-alcohol phosphatidyltransferase 4o6m Archaeoglobus fulgidus Archaebac. 2 12 30.0 ± 1.3 3 ± 1 -96.6
2.4.16.02. Defensin ARD1 1ozz Archaeoprepona demophon Secreted 1 0 4.9 ± 1.7 31 ± 17 -7.1
1.1.12.10. Voltage-gated sodium channel Nav1.7- NavAb, with antagonist 5ek0 Arcobacter butzleri Bact. Gram-neg inner 4 24 30.2 ± 0.6 0 ± 0 -236.2
1.1.12.10. Voltage-gated sodium channel NavAb, structure 4 (closed) 5vb2 Arcobacter butzleri Bact. Gram-neg inner 4 24 31.0 ± 0.8 0 ± 0 -228.1
1.1.12.10. Voltage-gated sodium channel NavAb, structure 5 (open) 5vb8 Arcobacter butzleri Bact. Gram-neg inner 4 24 31.4 ± 0.8 0 ± 0 -229.5
1.1.12.10. Voltage-gated sodium channel Nav1.7- NavAb, structure 1 3rvy Arcobacter butzleri Bact. Gram-neg inner 4 24 29.6 ± 0.4 0 ± 0 -216.9
1.1.12.10. Voltage-gated sodium channel NavAb, structure 6 5yua Arcobacter butzleri Bact. Gram-neg inner 4 26 29.4 ± 0.8 0 ± 0 -229.8
1.1.12.10. Voltage-gated sodium channel NavAb, structure 3 5klb Arcobacter butzleri Bact. Gram-neg inner 4 24 30.8 ± 0.3 1 ± 0 -218.3
1.1.12.10. Voltage-gated sodium channel NavAb, structure 2 4ekw Arcobacter butzleri Bact. Gram-neg inner 4 24 29.4 ± 0.5 0 ± 0 -201.0
3.2.01.01. Arenicin-2 2jni Arenicola marina Secreted 1 0 2.1 ± 1.1 82 ± 15 -5.2
3.2.01.01. Arenicin-1 2jsb Arenicola marina Secreted 1 0 2.4 ± 2.1 80 ± 11 -5.2
3.2.01.01. Arenicin-3 5y0i Arenicola marina Secreted 1 0 3.0 ± 1.6 83 ± 5 -3.9
3.2.01.01. Arenicin-2, dimer 2l8x Arenicola marina Secreted 2 0 2.7 ± 1.1 87 ± 4 -4.0
2.3.33.01. Endo-beta-N-acetylglucosaminidase 2vtf Arthrobacter protophormiae Secreted 1 0 4.1 ± 0.7 52 ± 2 -6.5
2.4.16.05. Micasin 2lr5 Arthroderma otae Secreted 1 0 8.3 ± 0.6 58 ± 6 -7.8
2.1.08.01. Cytochrome c6 1f1f Arthrospira maxima Thylakoid 1 0 4.8 ± 1.6 80 ± 15 -3.5
1.1.08.01. F0 ATP synthase 2xqu Arthrospira platensis Thylakoid 15 30 31.8 ± 0.8 0 ± 0 -129.7
3.1.21.01. Cecropin-P1 2n92 Ascaris suum Secreted 1 0 1.6 ± 3.4 90 ± 0 -4.1
1.1.05.04. Succinate dehydrogenase (mitochondrial respiratory complex II) 3vr8 Ascaris suum Mitochon. inner 2 6 30.4 ± 1.2 10 ± 1 -57.1
2.1.64.01. AFMP4P 5j5k Aspergillus fumigatus Eukaryo. plasma 1 0 3.9 ± 1.9 73 ± 13 -6.1
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 5frb Aspergillus fumigatus Endoplasm. reticulum 1 0 11.8 ± 0.5 59 ± 1 -13.2
2.3.06.09. Cutinase 1 3gbs Aspergillus oryzae Secreted 1 0 11.2 ± 0.5 55 ± 5 -12.6
2.2.34.07. Asteropsin A 3q8j Asteropus sp. Secreted 1 0 2.8 ± 1.7 75 ± 15 -3.0
2.2.34.07. Asteropsin B 2lzx Asteropus sp. Secreted 1 0 2.2 ± 1.7 90 ± 21 -3.3
2.2.34.07. Asteropsin D 2lzy Asteropus sp. Secreted 1 0 4.7 ± 1.5 49 ± 29 -3.0
2.2.34.07. Asteropsin E 2m3j Asteropus sp. Secreted 1 0 4.5 ± 1.1 65 ± 7 -3.6
2.2.34.07. Asteropsin F 2n2g Asteropus sp. Secreted 1 0 4.3 ± 1.7 60 ± 11 -3.4
2.2.34.07. Asteropsin G 2n3p Asteropus sp. Secreted 1 0 8.0 ± 1.4 37 ± 17 -5.3
3.2.05.02. Benenodin-1, state 2 6b5w Asticcacaulis benevestitus Secreted 1 0 3.3 ± 1.6 82 ± 7 -5.8
3.2.05.02. Benenodin-1, state 1 5tj1 Asticcacaulis benevestitus Secreted 1 0 6.0 ± 2.6 78 ± 5 -7.6
3.2.05.02. Astexin-4 2n6u Asticcacaulis excentricus Secreted 1 0 2.8 ± 1.1 41 ± 21 -3.8
3.2.05.02. Astexin-1, structure 1 2lti Asticcacaulis excentricus Secreted 1 0 2.4 ± 1.0 85 ± 9 -3.6
3.2.05.02. Astexin-1, structure 2 2m37 Asticcacaulis excentricus Secreted 1 0 3.2 ± 1.1 83 ± 13 -5.1
3.2.05.02. Astexin-3 2m8f Asticcacaulis excentricus Secreted 1 0 6.2 ± 1.1 64 ± 28 -5.9
3.1.12.01. Sarafotoxin-B 1srb Atractaspis engaddensis (Israeli burrowing asp) Secreted 1 0 4.9 ± 1.9 62 ± 10 -4.1
3.1.12.01. Sarafotoxin-M 2ldf Atractaspis microlepidota microlepidota Secreted 1 0 2.3 ± 1.5 30 ± 35 -2.1
3.1.12.01. Sarafotoxin-I3 2lde Atractaspis microlepidota microlepidota Secreted 1 0 4.2 ± 3.6 86 ± 8 -2.8
2.2.34.02. Robustoxin 1qdp Atrax robustus Secreted 1 0 1.8 ± 1.9 86 ± 18 -5.0
2.1.01.01. Myotoxin II 2aoz Atropoides nummifer Secreted 1 0 3.4 ± 0.7 80 ± 3 -11.8
2.1.60.01. Aurelin 2lg4 Aurelia aurita Secreted 1 0 2.0 ± 0.9 50 ± 6 -4.4
1.2.43.05. Major envelope glycoprotein 3duz Autographa californica nuclear polyhedrosis virus Viral 3 0 3.2 ± 0.4 4 ± 6 -9.3
3.1.07.10. Structural peptide 1 of bursal disease virus 2imu Avian infectious bursal disease virus Eukaryo. plasma 1 0 11.6 ± 4.0 76 ± 5 -17.5
3.1.07.09. Membrane fusion protein p15 2mns Baboon orthoreovirus Eukaryo. plasma 1 0 9.3 ± 7.0 86 ± 4 -9.4
1.2.18.01. Sortase B 1rz2 Bacillus anthracis Bact. Gram-pos plas. 1 0 3.0 ± 0.6 82 ± 6 -5.8
2.2.35.01. Anthrolysin O 3cqf Bacillus anthracis Secreted 1 0 2.8 ± 1.0 75 ± 1 -5.8
1.3.25.04. Protective antigen 3j9c Bacillus anthracis Secreted 7 14 34.6 ± 1.2 0 ± 0 -76.8
2.3.17.02. Dihydropteroate synthase 1tx2 Bacillus anthracis Bact. Gram-pos plas. 2 0 2.5 ± 0.3 90 ± 2 -7.7
2.3.22.02. NrdI protein 2xod Bacillus anthracis Undefined 1 0 4.1 ± 0.4 72 ± 3 -4.8
1.2.06.01. Spore surface protein Bcla 1wck Bacillus anthracis Bact. Gram-pos plas. 3 0 3.3 ± 0.2 8 ± 5 -8.9
3.3.01.01. Gramicidin A, head-to-head dimer, right-handed 1grm Bacillus brevis Secreted 2 2 23.2 ± 4.0 7 ± 9 -28.1
3.3.01.01. Gramicidin C, head-to-head dimer, right-handed 1jo4 Bacillus brevis Secreted 2 2 20.4 ± 1.7 25 ± 3 -25.5
3.3.01.01. Gramicidin A, shortened, cross-linked, head-to-head dimer, right-handed 1tkq Bacillus brevis Secreted 2 2 28.4 ± 3.9 13 ± 7 -30.0
3.3.01.01. Gramicidin A, cross-linked, parallel double helix, left-handed 1kqe Bacillus brevis Secreted 2 2 34.4 ± 4.7 17 ± 17 -32.9
3.2.09.03. Tyrocidine A 4m6e Bacillus brevis Secreted 1 0 6.8 ± 0.9 56 ± 8 -9.0
3.3.01.01. Gramicidin A, anti-parallel double helix, left-handed, 2 (cubic phase) 2xdc Bacillus brevis Secreted 2 2 21.8 ± 1.6 48 ± 4 -28.2
3.2.09.02. Gramicidin S 1tk2 Bacillus brevis Secreted 1 0 8.5 ± 1.7 86 ± 21 -8.6
3.3.01.01. Gramicidin A, anti-parallel double helix, left-handed, 3 (CsCl complex) 1c4d Bacillus brevis Secreted 2 2 19.6 ± 2.3 24 ± 10 -20.9
3.3.01.01. Gramicidin A, anti-parallel double helix, left-handed, 1 3zq8 Bacillus brevis Secreted 2 2 29.8 ± 0.6 12 ± 14 -24.1
3.2.09.03. Tyrocidine A analogue AC3.27 6b34 Bacillus brevis Secreted 1 0 7.6 ± 1.6 74 ± 9 -9.1
3.3.01.01. Gramicidin A, anti-parallel double helix, left-handed, 4 (KSCN complex) 1gmk Bacillus brevis Secreted 2 2 22.4 ± 2.4 10 ± 11 -24.5
3.3.01.01. Gramicidin A, anti-parallel double helix, right-handed, complex with KI 2izq Bacillus brevis Secreted 2 2 18.8 ± 1.2 28 ± 25 -18.7
3.2.09.03. Tyrocidine A analogue AC3.28 6b35 Bacillus brevis Secreted 1 0 6.3 ± 1.6 79 ± 13 -10.1
3.3.01.01. Gramicidin A, anti-parallel double helix, right-handed, complex with CsCl 1av2 Bacillus brevis Secreted 2 2 18.2 ± 0.8 35 ± 4 -19.4
3.3.01.01. Gramicidin A, parallel double helix, left-handed 1mic Bacillus brevis Secreted 2 2 27.5 ± 5.4 19 ± 17 -19.7
3.3.01.01. Gramicidin A, anti-parallel double helix, right-handed, complex with NaI 3l8l Bacillus brevis Secreted 2 2 19.2 ± 1.5 30 ± 10 -18.5
3.3.01.01. Gramicidin B, head-to-head dimer, right-handed 1jo3 Bacillus brevis Secreted 2 2 22.4 ± 2.3 13 ± 3 -25.9
2.1.03.01. Phospholipase C 1p6d Bacillus cereus Secreted 1 0 2.8 ± 1.0 52 ± 6 -8.4
1.1.12.12. NaK potassium channel, different strain of Bacillus cereus 3ouf Bacillus cereus Bact. Gram-pos plas. 4 8 27.9 ± 1.3 0 ± 0 -91.0
2.1.62.01. Thuricin alpha 2l9x Bacillus cereus Secreted 1 0 7.1 ± 3.2 84 ± 7 -7.8
1.1.12.12. NaK potassium channel, open state 3e86 Bacillus cereus Bact. Gram-pos plas. 4 8 27.6 ± 0.9 0 ± 0 -90.0
1.1.43.01. Saccharide transporter, EIIC (ChbC), outward-facing 5iws Bacillus cereus Bact. Gram-pos plas. 2 20 31.2 ± 1.0 0 ± 0 -161.7
2.1.62.01. Thuricin beta 2la0 Bacillus cereus Secreted 1 0 10.0 ± 2.6 37 ± 7 -8.8
2.1.62.01. Thuricin 17 2lbz Bacillus cereus Secreted 1 0 3.4 ± 2.6 88 ± 0 -7.7
1.1.12.12. NaK potassium channel 2ahy Bacillus cereus Bact. Gram-pos plas. 4 8 29.5 ± 0.7 0 ± 1 -105.7
2.3.22.02. NrdI protein 2x2o Bacillus cereus Undefined 1 0 3.6 ± 0.5 77 ± 4 -4.6
1.1.43.01. Saccharide transporter, EIIC (ChbC), inward-facing 3qnq Bacillus cereus Bact. Gram-pos plas. 2 20 29.6 ± 1.0 1 ± 0 -140.6
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1gym Bacillus cereus Secreted 1 0 4.9 ± 1.0 67 ± 11 -7.2
2.3.06.05. Carboxylesterase 2h1i Bacillus cereus Bact. Gram-pos plas. 1 0 2.3 ± 1.8 32 ± 31 -3.6
1.1.83.01. Bacterial translocator protein, dimer 4ryi Bacillus cereus Bact. Gram-pos plas. 2 10 30.4 ± 1.2 2 ± 0 -89.7
2.3.24.01. Phosphonoacetaldehyde hydrolase 1rdf Bacillus cereus Undefined 1 0 4.3 ± 0.9 68 ± 4 -5.1
2.4.04.01. Sphingomyelinase C 2ddt Bacillus cereus Secreted 1 0 4.1 ± 1.1 59 ± 8 -7.6
1.1.83.01. Bacterial translocator protein, monomer 4rym Bacillus cereus Bact. Gram-pos plas. 1 5 31.4 ± 1.4 3 ± 0 -52.8
1.1.12.12. NaK potassium channel, open state, mutant with DMA 4r7c Bacillus cereus Bact. Gram-pos plas. 4 8 27.8 ± 0.9 0 ± 0 -41.0
1.1.26.01. MhsT transporter, inward-facing state 4us3 Bacillus halodurans Bact. Gram-pos plas. 1 11 29.8 ± 0.8 11 ± 1 -87.1
1.1.30.01. Membrane protein insertase YidC 2 3wo7 Bacillus halodurans Bact. Gram-pos plas. 1 5 29.0 ± 1.3 12 ± 0 -58.2
1.1.38.01. MATE multidrug transporter DinF-BH 4lz6 Bacillus halodurans Bact. Gram-pos plas. 1 12 31.0 ± 1.1 5 ± 1 -96.5
3.4.02.05. Lichenicidin VK21 A2 2kto Bacillus licheniformis Secreted 1 0 6.6 ± 4.2 75 ± 3 -6.9
3.4.02.05. Lichenicidin VK21 A1 2ktn Bacillus licheniformis Secreted 1 0 7.0 ± 1.5 77 ± 13 -5.9
1.1.08.01. F0 ATP synthase, subunit c 1wu0 Bacillus ps3 Bact. Gram-pos plas. 1 2 31.9 ± 2.7 44 ± 1 -23.2
1.1.08.01. F0 ATP synthase, structure 1 2x2v Bacillus pseudofirmus Bact. Gram-pos plas. 13 26 35.3 ± 1.2 0 ± 0 -137.7
1.1.08.01. F0 ATP synthase, structure 2 3zo6 Bacillus pseudofirmus Bact. Gram-pos plas. 12 24 39.6 ± 1.1 1 ± 0 -130.6
2.3.06.07. Thermostable lipase 4fdm Bacillus sp. Secreted 1 0 5.2 ± 0.6 28 ± 2 -8.5
3.4.02.02. Mersacidin, crystal structure 1qow Bacillus sp. Secreted 3 0 3.2 ± 2.7 72 ± 31 -5.5
3.4.02.02. Mersacidin, structure in methanol solution 1mqx Bacillus sp. Secreted 1 0 1.9 ± 1.3 87 ± 15 -2.9
3.4.02.02. Mersacidin, structure in DPC micelles 1mqy Bacillus sp. Secreted 1 0 5.3 ± 0.9 90 ± 12 -6.1
3.4.02.02. Mersacidin, structure of lipid II bound peptide in DPC micelles 1mqz Bacillus sp. Secreted 1 0 4.2 ± 2.8 83 ± 15 -4.2
2.3.06.07. Organic solvent tolerant lipase 42 4fkb Bacillus sp. Secreted 1 0 5.0 ± 0.7 26 ± 3 -6.9
1.1.07.01. Nitric oxide reductase 3ayf Bacillus stearothermophilus Bact. Gram-pos plas. 1 14 31.6 ± 0.8 8 ± 0 -109.3
2.3.06.07. Lipase L1 1ku0 Bacillus stearothermophilus Secreted 1 0 4.0 ± 0.6 23 ± 9 -8.9
2.3.06.07. Lipase L1, isoform 2 4fmp Bacillus stearothermophilus Secreted 1 0 5.0 ± 1.6 25 ± 12 -8.9
2.3.06.07. Lipase L1, isoform 1 1ji3 Bacillus stearothermophilus Secreted 1 0 3.5 ± 1.7 22 ± 10 -8.0
1.1.106.01. Phosphatidylglycerol phosphate phosphatase 5jki Bacillus subtilis Bact. Gram-pos plas. 1 6 28.6 ± 1.4 38 ± 0 -56.7
2.1.62.02. Subtilosin A 1pxq Bacillus subtilis Secreted 1 0 7.6 ± 0.8 86 ± 3 -9.3
2.1.44.01. Sublancin-168 2mij Bacillus subtilis Secreted 1 0 4.0 ± 5.0 83 ± 0 -4.2
3.4.04.02. Surfactin 2npv Bacillus subtilis Secreted 1 0 11.3 ± 2.1 55 ± 13 -11.3
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2 2w8d Bacillus subtilis Bact. Gram-pos plas. 1 0 0.0 ± 6.0 83 ± 58 -1.6
2.3.16.02. Translocation ATPase SecA 1tf5 Bacillus subtilis Bact. Gram-pos plas. 1 0 2.5 ± 1.1 64 ± 5 -7.0
1.1.12.19. TrkH/TrkA potassium transport complex, structure 1 4j7c Bacillus subtilis Bact. Gram-pos plas. 2 16 31.8 ± 1.0 0 ± 0 -165.6
3.1.33.01. Stage V sporulation protein M 2mvh Bacillus subtilis Vacuole 1 0 6.3 ± 1.0 90 ± 4 -9.9
1.1.75.02. Sec-independent protein translocase TatA 2l16 Bacillus subtilis Bact. Gram-pos plas. 1 1 27.6 ± 2.9 10 ± 1 -27.9
1.1.86.01. Protein YetJ, closed conformation 4pgr Bacillus subtilis Bact. Gram-pos plas. 1 7 29.8 ± 2.0 15 ± 2 -72.0
2.1.30.01. Membrane-integrating protein mistic, mstX 1ygm Bacillus subtilis Bact. Gram-pos plas. 1 0 2.6 ± 1.8 31 ± 6 -5.2
2.1.34.01. Septium site-determining protein DivIVA 2wuj Bacillus subtilis Bact. Gram-pos plas. 2 0 4.0 ± 1.8 2 ± 18 -5.4
1.1.86.01. Protein YetJ, open conformation 4pgs Bacillus subtilis Bact. Gram-pos plas. 1 7 30.8 ± 1.6 7 ± 3 -67.7
1.1.39.05. Probable thiamine permease YkoE 5edl Bacillus subtilis Bact. Gram-pos plas. 1 6 31.4 ± 1.6 19 ± 3 -66.2
1.1.12.19. TrkH/TrkA potassium transport complex, structure 2 5but Bacillus subtilis Bact. Gram-pos plas. 2 16 32.0 ± 0.7 0 ± 0 -143.8
2.2.41.04. Antimicrobial peptide LCI 2b9k Bacillus subtilis Secreted 1 0 1.6 ± 2.9 89 ± 19 -4.4
1.2.32.01. Fatty-acid peroxygenase 1izo Bacillus subtilis Bact. Gram-pos plas. 1 0 1.2 ± 0.3 76 ± 1 -5.5
1.1.64.01. Ca2+/H+ antiporter YfkE, different conformation 4kjs Bacillus subtilis Bact. Gram-pos plas. 3 33 31.2 ± 0.8 0 ± 0 -201.6
1.1.11.01. SecA-SecY complex 5eul Bacillus subtilis Bact. Gram-pos plas. 3 12 27.0 ± 1.2 7 ± 1 -79.5
2.3.06.19. Lipase A 1isp Bacillus subtilis Secreted 1 0 1.9 ± 0.8 59 ± 12 -5.2
1.1.64.01. Ca2+/H+ antiporter YfkE 4kjr Bacillus subtilis Bact. Gram-pos plas. 3 33 29.8 ± 0.4 0 ± 0 -181.6
3.4.12.03. Bacitracin 4k7t Bacillus subtilis Secreted 1 0 9.0 ± 0.9 69 ± 8 -8.4
3.4.04.04. Bacillomycin Lc 2igz Bacillus subtilis Secreted 1 0 9.0 ± 2.8 57 ± 11 -6.9
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1t6m Bacillus thuringiensis Secreted 1 0 3.8 ± 1.4 89 ± 13 -4.9
2.1.27.01. Cry3Bb1 1ji6 Bacillus thuringiensis Secreted 1 0 3.8 ± 1.6 64 ± 6 -4.2
2.1.27.01. Cry2Aa 1i5p Bacillus thuringiensis Secreted 1 0 3.4 ± 1.2 16 ± 12 -7.0
1.2.11.01. Capsid protein G8P 1ifi Bacteriophage fd Secreted 15 15 36.8 ± 0.2 0 ± 0 -69.8
1.2.11.01. Capsid protein G8P 1ifk Bacteriophage If1 Secreted 15 15 31.8 ± 0.7 0 ± 0 -83.5
1.2.11.01. Capsid protein G8P 1ifl Bacteriophage IKe Secreted 10 10 30.8 ± 0.8 0 ± 0 -93.6
1.2.11.02. Capsid protein G8P 2mjz Bacteriophage M13 Viral 10 10 30.8 ± 0.3 0 ± 0 -20.4
1.2.11.02. Capsid protein G8P, monomer 2cps Bacteriophage M13 Viral 1 1 30.8 ± 3.1 15 ± 3 -19.9
1.2.11.02. Capsid protein G8P 1ql1 Bacteriophage Pf1 Secreted 12 12 31.1 ± 1.6 10 ± 0 -55.9
1.2.11.02. Capsid protein G8P, monomer 2xkm Bacteriophage Pf1 Secreted 1 1 29.2 ± 4.6 34 ± 1 -23.0
1.2.11.02. Capsid protein G8P 1ifp Bacteriophage Pf3 Secreted 12 12 34.2 ± 0.1 6 ± 6 -57.6
1.2.11.02. Capsid protein G8P 1hgz Bacteriophage PH75 Secreted 15 15 29.2 ± 2.3 8 ± 7 -46.5
2.2.19.01. Adsorption protein p2 1n7v Bacteriophage prd1 Viral 1 0 8.7 ± 0.4 81 ± 1 -8.6
1.2.11.02. Capsid protein G8P 2ifo Bacteriophage Xf Secreted 12 12 32.2 ± 1.9 16 ± 3 -58.4
2.2.13.01. Cellulosomal scaffoldin 2xbt Bacteroides cellulosolvens Secreted 1 0 4.4 ± 0.3 84 ± 14 -5.8
1.3.20.01. SusD-SusC complex 5t3r Bacteroides thetaiotaomicron Bact. Gram-neg outer 1 22 25.0 ± 0.6 3 ± 0 -78.5
1.3.20.01. SusD-SusC complex, a dimer 5t4y Bacteroides thetaiotaomicron Bact. Gram-neg outer 2 44 25.0 ± 0.8 1 ± 0 -137.7
1.3.20.01. SusD-SusC complex, BT_2263, a dimer 5fq6 Bacteroides thetaiotaomicron Bact. Gram-neg outer 2 44 26.6 ± 2.2 0 ± 0 -142.4
2.1.14.02. SusD superfamily protein 3myv Bacteroides vulgatus Secreted 1 0 4.0 ± 1.0 64 ± 2 -6.0
1.2.43.02. E1/E2 envelope glycoprotein complex 2yew Barmah forest virus Viral 8 8 30.0 ± 0.8 0 ± 0 -53.5
2.2.21.05. Kunitz-type proteinase inhibitor BbCI 2gzb Bauhinia bauhinioides Secreted 1 0 7.9 ± 0.3 28 ± 3 -9.3
1.1.25.09. Iron-regulated transporter, outward-facing state 5ayn Bdellovibrio bacteriovorus Bact. Gram-neg inner 1 12 29.8 ± 1.8 8 ± 4 -82.9
1.1.25.09. Iron-regulated transporter, inward-facing state 5ayo Bdellovibrio bacteriovorus Bact. Gram-neg inner 1 12 31.6 ± 0.7 7 ± 1 -89.2
3.1.28.03. Maximin-4 2mhw Bombina maxima Secreted 1 0 4.4 ± 1.0 75 ± 3 -6.3
3.1.28.03. Bombinin-H5 2ap8 Bombina variegata (Yellow-bellied toad) Secreted 1 0 8.6 ± 4.2 77 ± 3 -10.6
2.2.46.01. Low molecular mass 30 kDa lipoprotein 19G1 4iy8 Bombyx mori Secreted 1 0 4.3 ± 1.2 31 ± 8 -4.2
3.1.21.08. Moricin 1kv4 Bombyx mori Secreted 1 0 6.1 ± 0.6 77 ± 14 -10.3
3.2.06.01. Paralytic peptide 1irr Bombyx mori Secreted 1 0 2.2 ± 1.9 74 ± 19 -3.3
1.1.114.01. ZIP zinc transporter 5tsa Bordetella bronchiseptica Bact. Gram-neg inner 1 8 30.2 ± 1.6 19 ± 0 -64.6
2.2.45.01. Pertactin, complex with phage tail protein 2iou Bordetella bronchiseptica Bact. Gram-neg outer 4 0 3.9 ± 1.2 82 ± 2 -8.2
1.3.17.01. Filamentous hemagglutinin transporter FhaC, structure 2 4ql0 Bordetella pertussis Bact. Gram-neg outer 1 16 23.2 ± 0.9 10 ± 0 -62.7
1.3.20.01. Outer membrane receptor FauA 3efm Bordetella pertussis Bact. Gram-neg outer 1 22 24.7 ± 0.6 11 ± 0 -77.5
1.1.96.01. Fluoride ion transporter CrcB, structure 2 6bqo Bordetella pertussis Bact. Gram-neg inner 2 8 30.2 ± 1.4 13 ± 3 -66.0
1.3.17.01. Filamentous hemagglutinin transporter FhaC, structure 1 3njt Bordetella pertussis Bact. Gram-neg outer 1 16 23.6 ± 0.9 7 ± 0 -65.8
1.3.11.01. Autotransporter BrkA 3qq2 Bordetella pertussis Bact. Gram-neg outer 1 12 24.6 ± 1.5 4 ± 1 -44.1
2.2.45.01. Pertactin autotransporter 1dab Bordetella pertussis Bact. Gram-neg outer 1 0 2.6 ± 1.1 73 ± 6 -5.9
1.1.96.01. Fluoride ion transporter CrcB, structure 1 5a40 Bordetella pertussis Bact. Gram-neg inner 2 8 30.8 ± 1.7 20 ± 1 -71.9
2.1.12.01. Outer surface protein C 1g5z Borrelia burgdorferi Bact. Gram-neg outer 2 0 3.6 ± 0.6 2 ± 8 -7.0
2.2.04.01. Retinoid isomerohydrolase, conformation 2 4f2z Bos taurus Eukaryo. plasma 1 0 3.7 ± 0.9 56 ± 2 -9.2
3.1.29.01. Cathelicidin-6 2ket Bos taurus Secreted 1 0 7.1 ± 0.7 82 ± 3 -13.6
2.1.20.01. Osteocalcin 4mzz Bos taurus Secreted 1 0 1.8 ± 1.1 43 ± 8 -3.0
1.1.10.08. Multidrug resistance protein 1 (MRP1), structure 3 6bhu Bos taurus Eukaryo. plasma 1 17 31.0 ± 0.8 14 ± 0 -116.5
1.1.01.02. Rhodopsin, with cyclic retinal analog 5te5 Bos taurus Eukaryo. plasma 1 7 31.0 ± 1.2 11 ± 2 -72.3
2.2.06.01. Beta-lactoglobulin 3nq9 Bos taurus Secreted 1 0 0.5 ± 0.9 89 ± 4 -2.7
1.1.36.01. CLC-K chloride channel, structure 2 5tr1 Bos taurus Eukaryo. plasma 2 28 31.4 ± 1.0 1 ± 0 -135.2
2.2.04.01. Retinoid isomerohydrolase, conformation 3 4f30 Bos taurus Eukaryo. plasma 1 0 3.4 ± 1.4 61 ± 7 -10.9
2.1.20.01. Coagulation factor X, GLA domain 1iod Bos taurus Secreted 1 0 3.3 ± 0.9 25 ± 15 -5.2
1.1.07.01. Mitochondrial cytochrome c oxidase, with cytochrome c 5iy5 Bos taurus Mitochon. inner 20 56 25.8 ± 1.2 0 ± 0 -204.7
2.2.06.02. Muscle fatty acid binding protein 1bwy Bos taurus Eukaryo. plasma 1 0 4.8 ± 1.3 71 ± 12 -6.6
3.1.29.01. Cathelicidin-5 2ndc Bos taurus Secreted 1 0 2.1 ± 2.1 82 ± 17 -3.7
3.2.01.06. Lactoferricin B, peptide 38-49 1y58 Bos taurus Secreted 1 0 2.9 ± 1.4 86 ± 18 -3.7
2.2.06.01. Allergen Bos d 2 1bj7 Bos taurus Secreted 1 0 3.1 ± 1.3 50 ± 6 -3.5
1.1.06.01. Cytochrome bc1, mitochondrial, structure 2 2fyu Bos taurus Mitochon. inner 12 26 29.8 ± 0.5 0 ± 0 -182.9
2.2.14.01. Lactadherin 3bn6 Bos taurus Secreted 1 0 2.8 ± 0.5 11 ± 4 -7.2
1.2.32.01. Cholesterol side-chain cleavage enzyme (P450 11A1) 3mzs Bos taurus Mitochon. inner 1 0 3.2 ± 0.3 33 ± 1 -6.7
1.1.14.01. Aquaporin-1 1j4n Bos taurus Eukaryo. plasma 4 32 31.8 ± 1.0 0 ± 0 -129.2
2.2.31.01. Collagen-binding type II domain of seminal plasma protein PDC-109 1h8p Bos taurus Secreted 2 0 10.5 ± 0.9 87 ± 7 -16.6
2.3.16.03. Transducin 1got Bos taurus Eukaryo. plasma 3 0 4.9 ± 1.2 61 ± 8 -7.0
3.1.29.02. Indolicidin analogue (cathelicidin-4) 1qx9 Bos taurus Secreted 1 0 6.6 ± 1.9 46 ± 15 -7.7
2.3.06.04. Palmitoyl protein thioesterase 1 1eh5 Bos taurus Lysosome 1 0 5.3 ± 0.9 59 ± 6 -8.1
1.1.06.01. Cytochrome bc1, mitochondrial, bovine/chicken, structure 1 1bcc Bos taurus Mitochon. inner 24 10 29.8 ± 0.6 0 ± 0 -197.0
1.1.04.01. Respiratory Complex I, deactive state 5o31 Bos taurus Mitochon. inner 21 79 29.0 ± 0.0 7 ± 0 -220.1
1.2.32.01. Steroid 21-hydroxylase (P450 C21) 3qz1 Bos taurus Endoplasm. reticulum 1 0 5.9 ± 1.6 72 ± 3 -10.4
1.1.14.01. Aquaporin-0 1ymg Bos taurus Eukaryo. plasma 4 32 31.3 ± 1.2 0 ± 0 -138.4
2.2.37.01. Primary amine oxidase, liver isozyme 1tu5 Bos taurus Secreted 2 0 2.4 ± 1.2 89 ± 0 -6.1
2.3.06.01. Bile-salt activated lipase, conformation 2 1akn Bos taurus Secreted 1 0 3.8 ± 1.5 77 ± 15 -6.7
1.1.01.02. Rhodopsin, inactive, structure 3 1u19 Bos taurus Eukaryo. plasma 1 7 31.2 ± 1.5 12 ± 1 -71.9
1.1.06.01. Cytochrome bc1, mitochondrial, bovine/chicken, structure 2 3bcc Bos taurus Mitochon. inner 24 10 28.6 ± 1.0 0 ± 0 -190.1
1.2.39.03. Disintegrin and metalloproteinase domain-containing protein 10 2ao7 Bos taurus Golgi 1 0 3.1 ± 1.4 81 ± 6 -5.7
3.2.07.01. N-terminal beta-hairpin of ubiquitin 1e0q Bos taurus Undefined 1 0 3.5 ± 0.4 85 ± 0 -7.8
3.4.08.03. Oxytocin 1xy2 Bos taurus Secreted 1 0 2.1 ± 2.6 86 ± 12 -3.2
2.4.10.01. Synapsin I 1auv Bos taurus Vesicle 1 0 1.9 ± 1.1 86 ± 11 -5.2
1.1.07.01. Mitochondrial cytochrome c oxidase 2dyr Bos taurus Mitochon. inner 20 56 28.0 ± 0.6 0 ± 0 -198.1
2.2.41.01. Beta-defensin 12 1bnb Bos taurus Secreted 1 0 6.0 ± 1.6 88 ± 15 -10.8
2.1.18.01. Annexin VI 1avc Bos taurus Eukaryo. plasma 1 0 4.4 ± 1.0 83 ± 1 -8.1
1.1.04.01. Respiratory complex I 2ybb Bos taurus Mitochon. inner 26 115 30.0 ± 0.3 9 ± 0 -310.3
1.1.10.08. Multidrug resistance protein 1 (MRP1), structure 1 5uj9 Bos taurus Eukaryo. plasma 1 17 31.0 ± 0.2 7 ± 0 -110.7
3.1.11.01. Pancreatic hormone 1v1d Bos taurus Secreted 1 0 1.2 ± 3.0 79 ± 32 -1.9
1.1.06.01. Cytochrome bc1, mitochondrial, structure 4 5nmi Bos taurus Mitochon. inner 12 26 29.4 ± 1.0 0 ± 0 -161.4
1.1.01.02. Rhodopsin, partially active, photobleached 2i37 Bos taurus Eukaryo. plasma 1 7 31.9 ± 1.5 5 ± 1 -79.1
1.1.25.06. Glucose transporter GLUT5, inward-open 4yb9 Bos taurus Eukaryo. plasma 1 12 31.8 ± 1.0 6 ± 0 -89.9
2.2.15.01. Gamma-crystallin F 1m8u Bos taurus Secreted 1 0 0.7 ± 1.2 85 ± 4 -4.9
2.2.06.02. Myelin P2 protein 1pmp Bos taurus Eukaryo. plasma 1 0 2.7 ± 1.3 61 ± 13 -6.1
1.1.06.01. Cytochrome bc1, mitochondrial, structure 1 1l0l Bos taurus Mitochon. inner 12 26 30.0 ± 0.6 0 ± 0 -186.6
1.1.01.02. Rhodopsin, constitutively active mutant (metarhodopsin II), dimer 2x72 Bos taurus Eukaryo. plasma 2 14 30.0 ± 0.6 0 ± 0 -132.0
1.1.10.08. Multidrug resistance protein 1 (MRP1), structure 2 5uja Bos taurus Eukaryo. plasma 1 17 31.4 ± 0.8 16 ± 0 -103.8
2.3.13.02. Phosducin/Transducin beta-gamma complex, conformation 1 1a0r Bos taurus Eukaryo. plasma 3 0 2.3 ± 1.0 50 ± 4 -7.4
2.3.06.01. Bile-salt activated lipase, conformation 1 1aql Bos taurus Secreted 1 0 5.7 ± 1.1 78 ± 7 -9.6
2.1.18.01. Annexin IV, monomeric state 1ann Bos taurus Eukaryo. plasma 1 0 2.2 ± 1.0 77 ± 3 -6.0
1.1.01.02. Rhodopsin, inactive state, a dimer 2i36 Bos taurus Eukaryo. plasma 2 14 30.0 ± 1.4 4 ± 4 -125.6
2.3.06.01. Bile-salt activated lipase, conformation 3 2bce Bos taurus Secreted 1 0 5.3 ± 0.8 74 ± 6 -7.0
3.4.09.01. Granin, cyclic analogue 1n2y Bos taurus Secreted 1 0 1.9 ± 2.1 71 ± 16 -3.4
3.2.01.06. Lactoferricin B, peptide 10-19 1y5c Bos taurus Secreted 1 0 2.2 ± 1.2 54 ± 11 -3.4
1.1.01.02. Rhodopsin, inactive, complex with inverse agonist, 11-cis retinal 1gzm Bos taurus Eukaryo. plasma 1 7 32.2 ± 1.5 11 ± 1 -75.6
2.1.10.01. Glycolipid transfer protein, structure 1 1tfj Bos taurus Eukaryo. plasma 1 0 3.9 ± 1.0 90 ± 5 -8.3
3.2.01.06. Lactoferricin B, peptide 36-60 1lfc Bos taurus Secreted 1 0 4.6 ± 0.5 90 ± 6 -5.3
1.1.01.02. Opsin, complex with arrestin peptide 4pxf Bos taurus Eukaryo. plasma 1 7 31.6 ± 0.9 8 ± 1 -80.1
1.1.14.01. Aquaporin-0, open state 2b6p Bos taurus Eukaryo. plasma 4 32 31.1 ± 1.5 0 ± 1 -130.0
1.1.34.01. Mitochondrial ADP-ATP carrier, with carboxyatractyloside 2c3e Bos taurus Mitochon. inner 1 6 30.0 ± 1.0 4 ± 2 -44.0
2.1.18.01. Annexin IV 1i4a Bos taurus Eukaryo. plasma 3 0 2.5 ± 1.1 89 ± 3 -7.7
1.1.34.01. Mitochondrial ADP-ATP carrier 1okc Bos taurus Mitochon. inner 1 6 29.5 ± 1.7 14 ± 1 -44.6
1.1.04.01. Respiratory Complex I, class 1 5ldw Bos taurus Mitochon. inner 21 80 31.2 ± 0.3 5 ± 0 -221.8
1.1.17.02. Urea transporter 1 4ezc Bos taurus Eukaryo. plasma 3 30 31.2 ± 0.6 0 ± 0 -138.8
2.1.18.01. Annexin A2 4x9p Bos taurus Vesicle 1 0 2.7 ± 2.4 81 ± 12 -3.5
2.3.05.02. Adrenodoxin reductase of mitochondrial p450 systems, complex with adrenodoxin 1e6e Bos taurus Mitochon. inner 2 0 2.3 ± 1.0 11 ± 2 -4.1
1.1.09.01. Sodium-potassium pump, E2 state 4xe5 Bos taurus Eukaryo. plasma 3 12 29.6 ± 0.5 8 ± 0 -94.2
1.1.01.02. Rhodopsin, inactive, structure 2 (with beta-ionone) 3oax Bos taurus Eukaryo. plasma 1 7 30.9 ± 1.4 11 ± 0 -73.6
1.1.04.01. Respiratory Complex I, class 2 5lc5 Bos taurus Mitochon. inner 21 83 30.8 ± 0.5 8 ± 0 -216.6
2.1.10.01. Glycolipid transfer protein, structure 2 1wbe Bos taurus Eukaryo. plasma 1 0 1.1 ± 2.4 89 ± 8 -9.4
2.2.06.01. Retinol binding protein 4 1kt6 Bos taurus Secreted 1 0 4.3 ± 1.7 74 ± 12 -4.7
1.1.36.01. CLC-K chloride channel, structure 1 5tqq Bos taurus Eukaryo. plasma 2 28 31.4 ± 0.4 0 ± 0 -126.9
2.1.01.01. Phospholipase A2, group IB 1g4i Bos taurus Secreted 1 0 1.9 ± 0.5 87 ± 4 -7.4
1.1.09.01. Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 3tlm Bos taurus Endoplasm. reticulum 1 10 26.8 ± 0.0 22 ± 0 -57.4
3.1.01.03. Major prion protein, segment 1-30 1skh Bos taurus Eukaryo. plasma 1 1 20.8 ± 6.3 9 ± 5 -10.7
1.1.01.02. Rhodopsin, open channel structure 6fk6 Bos taurus Eukaryo. plasma 1 7 31.8 ± 1.2 8 ± 2 -82.1
1.1.04.01. Respiratory Complex I, class 3 5ldx Bos taurus Mitochon. inner 21 79 30.8 ± 0.0 6 ± 0 -237.1
1.1.01.02. Rhodopsin, active (metarhodopsin II), complex with peptide of transducin 3pqr Bos taurus Eukaryo. plasma 1 7 31.8 ± 1.1 9 ± 1 -78.3
2.2.14.01. C2 domains of coagulation factor Va 1sdd Bos taurus Eukaryo. plasma 2 0 3.7 ± 2.0 35 ± 8 -8.7
3.1.04.05. Lactotransferrin peptide (287-303) 2md1 Bos taurus Secreted 1 0 6.0 ± 1.0 71 ± 9 -7.3
1.1.01.02. Opsin, active, retinal-free state, dimer 3cap Bos taurus Eukaryo. plasma 2 14 30.8 ± 1.1 0 ± 0 -130.1
2.2.12.01. Epididymal secretory protein E1 1nep Bos taurus Secreted 1 0 8.0 ± 1.4 73 ± 14 -4.6
3.1.11.02. Glucagon 1kx6 Bos taurus Secreted 1 0 4.4 ± 2.0 70 ± 0 -6.4
2.2.04.01. Retinoid isomerohydrolase, conformation 1 3fsn Bos taurus Eukaryo. plasma 1 0 7.8 ± 1.0 73 ± 10 -10.3
1.1.06.01. Cytochrome bc1, mitochondrial, structure 3 1pp9 Bos taurus Mitochon. inner 10 24 29.8 ± 0.4 2 ± 0 -179.7
2.1.20.01. Prothrombin 1nl2 Bos taurus Eukaryo. plasma 1 0 3.9 ± 3.0 18 ± 24 -5.8
2.2.20.01. PH domain of GPCR kinase 2 2bcj Bos taurus Eukaryo. plasma 3 0 5.7 ± 1.5 85 ± 5 -10.4
1.1.01.02. Rhodopsin, active (metarhodopsin II), without transducin peptide 3pxo Bos taurus Eukaryo. plasma 2 14 31.8 ± 1.2 0 ± 0 -125.4
2.2.06.02. Cellular retinoic acid-binding protein 1 1cbr Bos taurus Eukaryo. plasma 1 0 6.5 ± 1.1 45 ± 11 -5.4
2.1.01.01. Myotoxin II 1y4l Bothrops asper Secreted 1 0 2.8 ± 0.8 76 ± 7 -10.3
2.1.01.01. Basic phospholipase A2 myotoxin III 5tfv Bothrops asper Secreted 1 0 6.1 ± 2.0 76 ± 5 -10.4
2.1.01.01. MTX-II chain A 4k06 Bothrops brazili Secreted 1 0 5.0 ± 1.3 60 ± 11 -7.1
2.1.01.01. Myotoxin 1god Bothrops godmani Secreted 1 0 3.0 ± 0.8 80 ± 8 -7.4
2.1.01.01. Phospholipase A2 bothropstoxin-2 2oqd Bothrops jararacussu Secreted 1 0 6.0 ± 0.6 85 ± 4 -7.8
2.1.01.01. Snake phospholipase A2, group II, hypotensive 1umv Bothrops jararacussu Secreted 1 0 5.1 ± 0.7 87 ± 4 -8.6
2.1.01.01. Snake phospholipase A2 homolog bothropstoxin-1, group II 3i03 Bothrops jararacussu Secreted 1 0 2.5 ± 0.5 76 ± 5 -10.6
2.1.01.01. Myotoxin II 1xxs Bothrops moojeni Secreted 1 0 4.5 ± 1.2 76 ± 10 -5.3
2.1.01.01. Basic phospholipase A2 homolog 1 3t0r Bothrops moojeni Secreted 1 0 3.7 ± 1.6 86 ± 12 -2.6
2.1.01.01. Phospholipase A2 BnSP-7 1pa0 Bothrops neuwiedi pauloensis Secreted 1 0 2.8 ± 1.0 78 ± 10 -6.9
2.1.01.01. Snake phospholipase A2-3, group II 1gmz Bothrops pirajai Secreted 1 0 3.8 ± 1.5 88 ± 10 -6.7
2.1.01.01. Snake phospholipase A2 homolog 1, group II 2ok9 Bothrops pirajai Secreted 1 0 3.5 ± 1.4 76 ± 7 -7.6
2.1.01.01. Snake phospholipase A2 homolog 2, group II 2q2j Bothrops pirajai Secreted 1 0 1.9 ± 1.2 89 ± 9 -5.6
3.1.07.05. Nonstructural protein 5a 2ajo Bovine viral diarrhea virus Endoplasm. reticulum 1 0 5.0 ± 1.0 86 ± 15 -11.8
2.2.34.02. U1-theraphotoxin-Ba1b 2kgh Brachypelma ruhnaui (Mexican golden redrump tarantula) Secreted 1 0 1.9 ± 2.5 83 ± 25 -1.9
2.4.16.09. S-locus pollen protein 1ugl Brassica campestris (Field mustard) Secreted 1 0 1.3 ± 0.6 51 ± 5 -3.4
2.4.01.01. Cholesterol oxidase 1coy Brevibacterium sterolicum Bact. Gram-pos plas. 1 0 4.4 ± 1.1 43 ± 10 -6.8
2.1.01.01. Snake phospholipase A2, isoform 3 2osn Bungarus caeruleus Secreted 1 0 2.4 ± 0.6 84 ± 4 -5.8
2.1.01.01. Snake phospholipase A2, group I, isoform 2 1u4j Bungarus caeruleus Secreted 1 0 2.2 ± 0.6 83 ± 4 -8.5
2.1.01.01. Snake phospholipase A2, group I, KPA2 1g2x Bungarus caeruleus Secreted 1 0 3.8 ± 1.5 84 ± 10 -5.4
2.1.01.01. Snake phospholipase A2, group I, isoform 1 1tc8 Bungarus caeruleus Secreted 1 0 3.1 ± 1.4 89 ± 11 -5.0
2.2.39.01. Bucandin 1f94 Bungarus candidus (Malayan krait) Secreted 1 0 5.0 ± 1.3 61 ± 6 -4.9
2.3.06.01. Acetylcholinesterase 4qww Bungarus fasciatus Secreted 1 0 2.0 ± 1.5 36 ± 32 -3.0
2.1.01.01. Phospholipase A2, beta bungarotoxin A1 chain, complex with bungarotoxin 1bun Bungarus multicinctus Secreted 2 0 1.7 ± 0.9 79 ± 3 -3.8
2.1.60.01. Potassium channel toxin Bgk 1bgk Bunodosoma granulifera Secreted 1 0 1.8 ± 1.7 19 ± 27 -2.9
2.2.07.01. Lipocalin BcnB 5ixg Burkholderia cepacia Bact. Gram-neg inner 1 0 2.0 ± 1.0 36 ± 5 -3.9
2.2.07.01. Lipocalin BcnA 5ixh Burkholderia cepacia Bact. Gram-neg inner 1 0 1.4 ± 2.6 28 ± 29 -1.7
1.1.10.01. Heme importer BhuUV 5b57 Burkholderia cepacia Bact. Gram-neg inner 2 20 28.6 ± 0.8 1 ± 1 -85.4
2.3.06.07. Lipase 5lip Burkholderia cepacia Secreted 1 0 9.0 ± 1.0 46 ± 2 -30.6
1.1.10.01. Heme importer BhuUV, with BhuT protein 5b58 Burkholderia cepacia Bact. Gram-neg inner 2 20 29.0 ± 1.0 0 ± 0 -81.6
1.1.28.05. Hopanoid transporter HpnN, structure 2 5khs Burkholderia multivorans Bact. Gram-neg inner 2 24 28.2 ± 0.8 0 ± 0 -100.7
1.1.28.05. Hopanoid transporter HpnN, structure 1 5khn Burkholderia multivorans Bact. Gram-neg inner 2 24 27.8 ± 1.0 0 ± 0 -111.2
1.1.12.14. Potassium channel Kirbac1.1, closed state 1p7b Burkholderia pseudomallei Bact. Gram-neg inner 4 8 33.1 ± 1.3 0 ± 0 -111.9
1.1.12.14. Potassium channel Kirbac1.1, closed state, refined 2wll Burkholderia pseudomallei Bact. Gram-neg inner 4 8 33.4 ± 2.4 0 ± 0 -109.1
1.1.12.14. Kir3.1-prokaryotic Kir channel chimera 2qks Burkholderia xenovorans Bact. Gram-neg inner 4 8 30.5 ± 1.4 0 ± 1 -88.6
2.4.16.03. Toxin I5a 1sis Buthus eupeus Secreted 1 0 3.1 ± 1.4 74 ± 16 -4.4
2.4.16.01. Tx10 alpha-like toxin 1kv0 Buthus martensii Secreted 1 0 1.9 ± 1.1 83 ± 11 -4.6
2.4.16.01. Alpha-like neurotoxin BmK-I 1djt Buthus martensii Secreted 2 0 3.8 ± 0.9 90 ± 15 -6.9
2.4.16.01. Neurotoxin 1dq7 Buthus tamulus Secreted 1 0 5.9 ± 1.8 88 ± 18 -8.1
1.1.15.01. Glutamate-gated chloride channel GluCl, with partial agonist 3rhw Caenorhabditis elegans Eukaryo. plasma 5 20 30.2 ± 0.7 0 ± 0 -107.9
1.1.15.01. Glutamate-gated chloride channel GluCl, POPC-bound conformation 4tnw Caenorhabditis elegans Eukaryo. plasma 5 20 30.6 ± 0.9 0 ± 0 -125.0
2.3.28.01. Aldo-keto reductase family 1 member C1 1qwk Caenorhabditis elegans Undefined 1 0 2.8 ± 1.0 66 ± 3 -6.3
1.1.20.02. Innexin-6 gap junction channel 5h1r Caenorhabditis elegans Eukaryo. plasma 8 40 30.6 ± 0.4 0 ± 0 -233.4
1.1.15.01. Glutamate-gated chloride channel GluCl, apo (non-conducting state) 4tnv Caenorhabditis elegans Eukaryo. plasma 5 20 30.8 ± 1.5 0 ± 0 -106.1
2.2.20.01. PH domain of muscle M-line assembly protein unc-89 1fho Caenorhabditis elegans Eukaryo. plasma 1 0 2.3 ± 1.2 25 ± 14 -4.3
1.1.104.01. Trimeric intracellular cation channel, structure 1 5eik Caenorhabditis elegans Endoplasm. reticulum 3 21 26.8 ± 0.3 0 ± 0 -45.3
2.1.24.01. Saposin-like protein 5 2jsa Caenorhabditis elegans Secreted 1 0 1.8 ± 2.2 47 ± 0 -3.7
1.1.10.04. Multidrug resistance protein pgp-1 4f4c Caenorhabditis elegans Eukaryo. plasma 1 14 32.0 ± 1.8 6 ± 0 -105.1
1.1.104.01. Trimeric intracellular cation channel, structure 2 5egi Caenorhabditis elegans Endoplasm. reticulum 3 21 30.8 ± 0.0 1 ± 0 -54.9
1.1.12.10. Voltage-gated sodium channel 4bgn Caldalkalibacillus thermarum Bact. Gram-pos plas. 4 24 27.0 ± 0.3 0 ± 0 -201.5
2.3.05.02. FAD-dependent pyridine nucleotide-disulfide oxidoreductase 4nwz Caldalkalibacillus thermarum Bact. Gram-pos plas. 2 0 6.2 ± 1.0 90 ± 2 -13.7
1.1.10.02. ABC-type polar amino acid transporter 4ymu Caldanaerobacter subterraneus Bact. Gram-pos plas. 2 10 29.8 ± 0.8 0 ± 0 -71.5
1.1.12.17. TRPML3 (mucolipin 3) channel, closed 5w3s Callithrix jacchus Lysosome 4 24 31.0 ± 0.8 0 ± 0 -213.0
1.1.38.01. Multidrug and toxic compound extrusion transporter 5xjj Camelina sativa Eukaryo. plasma 1 12 31.0 ± 0.6 4 ± 0 -91.4
2.2.12.01. Niemann-Pick type C2 protein 3web Camponotus japonicus Secreted 1 0 5.4 ± 0.3 73 ± 4 -7.6
1.1.28.02. Efflux pump membrane transporter CmeB, structure 2 5t0o Campylobacter jejuni Bact. Gram-neg inner 3 36 27.8 ± 0.6 0 ± 0 -183.8
2.3.16.01. Shikimate kinase 1via Campylobacter jejuni Bact. Gram-neg inner 2 0 3.9 ± 1.4 89 ± 11 -5.0
2.3.10.06. Glycosyltransferase PglH (WlaC) 6eji Campylobacter jejuni Bact. Gram-neg inner 1 0 5.6 ± 1.6 49 ± 1 -15.6
1.1.10.03. Oligosaccharide flippase PglK, inward-open, structure 1 5c78 Campylobacter jejuni Bact. Gram-neg inner 2 12 31.0 ± 1.1 2 ± 1 -120.6
1.1.10.03. Oligosaccharide flippase PglK, inward-open, structure 2 5c76 Campylobacter jejuni Bact. Gram-neg inner 2 12 32.0 ± 0.8 1 ± 0 -120.5
1.1.10.03. Oligosaccharide flippase PglK, inward-open, structure 3 5nbd Campylobacter jejuni Bact. Gram-neg inner 2 12 31.0 ± 0.6 6 ± 0 -97.7
1.1.28.02. Efflux pump membrane transporter CmeB, structure 1 5lq3 Campylobacter jejuni Bact. Gram-neg inner 36 3 28.2 ± 0.6 0 ± 0 -186.7
1.3.19.03. MOMP porin 5ldv Campylobacter jejuni Bact. Gram-neg outer 3 54 25.4 ± 0.6 0 ± 0 -125.2
1.3.24.01. Outer membrane channel CmeC 4mt4 Campylobacter jejuni Bact. Gram-neg outer 3 12 26.8 ± 0.4 0 ± 0 -67.1
1.1.52.01. Oligosaccharyltransferase PglB, structure 1 3rce Campylobacter lari Bact. Gram-neg inner 1 13 28.8 ± 0.9 8 ± 0 -89.6
1.1.52.01. Oligosaccharyltransferase PglB, structure 2 5ogl Campylobacter lari Bact. Gram-neg inner 1 13 29.0 ± 1.2 9 ± 0 -91.6
1.1.17.01. Ammonium transporter MEP2, structure 1 5aez Candida albicans Eukaryo. plasma 3 33 32.4 ± 0.8 0 ± 0 -154.4
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), structure 1 5tz1 Candida albicans Endoplasm. reticulum 1 0 8.7 ± 0.9 67 ± 4 -16.2
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), structure 2 5fsa Candida albicans Endoplasm. reticulum 1 0 9.0 ± 0.8 61 ± 2 -18.0
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), structure 3 5v5z Candida albicans Endoplasm. reticulum 1 1 30.8 ± 0.8 42 ± 4 -27.1
1.1.17.01. Ammonium transporter MEP2, structure 2 5ah3 Candida albicans Eukaryo. plasma 3 33 31.8 ± 0.7 0 ± 0 -157.0
2.3.06.06. Lipase A, closed state 3guu Candida antarctica Secreted 1 0 4.4 ± 1.0 80 ± 2 -10.9
2.3.06.06. Lipase B, circular permutation 3icv Candida antarctica Secreted 2 0 8.3 ± 0.8 83 ± 7 -11.3
2.3.06.06. Lipase B, open state 1lbs Candida antarctica Secreted 1 0 3.7 ± 1.0 76 ± 6 -12.7
2.3.06.06. Type-B carboxylesterase/lipase 1cle Candida cylindracea Secreted 1 0 10.2 ± 0.0 83 ± 0 -24.7
1.2.32.01. Lanosterol 14-alpha demethylase 5jlc Candida glabrata Endoplasm. reticulum 1 1 29.8 ± 0.7 25 ± 1 -31.5
2.3.06.06. Lipase 1, closed (inactive) state 1trh Candida rugosa Secreted 1 0 4.9 ± 1.3 85 ± 7 -7.4
2.3.06.06. Lipase 1, open (active) state 1lpp Candida rugosa Secreted 1 0 10.0 ± 0.4 83 ± 1 -28.0
2.3.06.06. Lipase 2 1gz7 Candida rugosa Secreted 1 0 4.8 ± 1.3 87 ± 10 -8.5
1.1.01.01. Bacteriorhodopsin 5jsi Candidatus Actinomarina minuta Bact. Gram-pos plas. 2 14 25.8 ± 0.6 1 ± 1 -71.9
1.1.01.01. Bacteriorhodopsin 6eyu Candidatus nanosalina Archaebac. 3 21 29.8 ± 1.0 0 ± 0 -101.2
1.1.11.01. Ribosome-translocon-oligosaccharyltransferase complex, structure 1 6ftj Canis lupus familiaris Endoplasm. reticulum 7 3 30.2 ± 2.0 7 ± 0 -155.2
1.1.11.01. Protein translocase Sec61, structure 1 4cg5 Canis lupus familiaris Endoplasm. reticulum 3 12 27.2 ± 0.9 5 ± 1 -72.9
1.1.11.01. Ribosome-translocon-oligosaccharyltransferase complex, structure 2 6ftg Canis lupus familiaris Endoplasm. reticulum 8 32 26.6 ± 0.0 6 ± 0 -170.4
1.1.11.01. Protein translocase Sec61, structure 2 4cg6 Canis lupus familiaris Endoplasm. reticulum 4 13 28.8 ± 1.2 7 ± 1 -79.9
1.1.11.01. Protein translocase Sec61, complex with ribosome 2wwb Canis lupus familiaris Endoplasm. reticulum 3 12 26.3 ± 0.5 13 ± 0 -60.5
1.1.11.01. Protein translocase Sec61, structure 3 4cg7 Canis lupus familiaris Endoplasm. reticulum 3 12 26.8 ± 0.3 10 ± 0 -69.9
1.1.11.01. Protein translocase Sec61, with signal peptide 3jc2 Canis lupus familiaris Endoplasm. reticulum 13 4 28.8 ± 1.3 1 ± 0 -73.0
2.3.06.03. Gastric lipase, open (active) state 1k8q Canis lupus familiaris Secreted 1 0 7.2 ± 0.5 78 ± 6 -12.6
1.1.11.01. Protein translocase Sec61, structure 4 5a6u Canis lupus familiaris Endoplasm. reticulum 3 12 29.8 ± 0.7 4 ± 1 -81.8
2.3.06.08. Pancreatic lipase-related protein 1 1rp1 Canis lupus familiaris Secreted 1 0 6.3 ± 1.0 79 ± 4 -7.5
2.1.18.01. Annexin 24 1dk5 Capsicum annuum Eukaryo. plasma 1 0 3.5 ± 1.3 76 ± 18 -4.4
2.2.41.01. Reptilian defensin 2b5b Caretta caretta Secreted 1 0 1.5 ± 0.4 73 ± 1 -4.1
3.1.16.02. Carnobacteriocin, X component 5ujr Carnobacterium maltaromaticum Secreted 1 0 5.4 ± 3.0 89 ± 13 -11.9
2.1.25.02. Carnocyclin A 2kjf Carnobacterium maltaromaticum Secreted 1 0 2.1 ± 1.1 61 ± 12 -4.6
3.1.16.02. Carnobacteriocin, Y component 5ujq Carnobacterium maltaromaticum Secreted 1 0 8.3 ± 3.0 57 ± 4 -9.3
2.1.42.01. Putative carnobacteriocin-B2 immunity protein 1tdp Carnobacterium maltaromaticum Secreted 1 0 4.4 ± 0.5 90 ± 9 -4.3
3.1.15.01. Carnobacteriocin B2 1cw5 Carnobacterium maltaromaticum Secreted 1 0 6.5 ± 0.3 89 ± 5 -9.9
2.4.06.04. STAR-related bacterial protein 1t17 Caulobacter crescentus Undefined 1 0 3.4 ± 0.7 63 ± 2 -8.1
3.2.05.02. Caulosegnin I 2lx6 Caulobacter segnis Secreted 1 0 2.9 ± 0.8 15 ± 5 -6.0
3.2.05.02. Caulosegnin II 5d9e Caulobacter segnis Secreted 1 0 8.9 ± 3.2 79 ± 8 -7.6
3.2.05.02. Caulonodin 2mlj Caulobacter sp. Secreted 1 0 2.4 ± 1.7 87 ± 15 -5.0
1.1.01.02. Leukotriene B4 receptor LTB4 5x33 Cavia porcellus Eukaryo. plasma 1 7 30.6 ± 1.0 6 ± 1 -68.7
2.3.06.08. Pancreatic lipase 1gpl Cavia porcellus Secreted 1 0 5.8 ± 1.0 86 ± 9 -7.8
2.3.04.01. Corticosteroid 11-beta-dehydrogenase, isozyme 1 3g49 Cavia porcellus Endoplasm. reticulum 2 0 7.0 ± 0.5 90 ± 1 -15.9
3.1.22.01. Antifungal peptide 2mp9 Cenchritis muricatus Secreted 1 0 1.2 ± 1.5 90 ± 26 -3.7
2.4.16.01. Alpha-toxin Cn12 1pe4 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.1 ± 2.3 17 ± 13 -3.1
2.4.16.01. Beta-toxin Cn5 2kja Centruroides noxius (Mexican scorpion) Secreted 1 0 4.1 ± 1.1 73 ± 6 -7.0
2.4.16.01. Beta-mammal toxin Cn2 2yc1 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.8 ± 1.1 68 ± 9 -3.8
2.4.16.03. Potassium channel toxin gamma-KTx 1.1 1ne5 Centruroides noxius (Mexican scorpion) Secreted 1 0 3.9 ± 1.0 62 ± 2 -5.2
2.4.16.01. Beta-toxin CsEI 1b3c Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.9 ± 1.2 70 ± 7 -3.9
2.4.16.01. Toxin CsEv1 1vna Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.9 ± 1.0 65 ± 10 -7.8
2.4.16.01. Alpha-toxin CsE5 1nra Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.3 ± 1.2 89 ± 22 -4.3
2.4.16.01. Toxin CsEv3 2sn3 Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.3 74 ± 17 -5.5
2.4.16.01. Neurotoxin 2 1jza Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.7 68 ± 15 -5.6
2.4.16.01. Alpha-like toxin CsEv5 1i6f Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.4 ± 1.3 59 ± 4 -5.8
2.1.15.01. Epsin-2 5oo7 Chaetomium thermophilum Eukaryo. plasma 2 0 5.7 ± 5.7 70 ± 0 -9.9
1.1.111.01. Prokaryotic otassium channel TMEM175 5vre Chamaesiphon minutus Bact. Gram-neg inner 4 24 30.2 ± 1.4 0 ± 0 -125.4
2.2.34.11. Circulin A 1bh4 Chassalia parviflora Secreted 1 0 3.9 ± 1.2 60 ± 18 -6.6
2.2.34.11. Circulin B 2eri Chassalia parviflora Secreted 1 0 5.0 ± 1.0 69 ± 20 -8.4
1.2.43.02. E1/E2 envelope glycoprotein complex 3j2w Chikungunya virus Viral 8 8 30.8 ± 0.9 2 ± 0 -134.1
1.2.43.02. E1 envelope glycoprotein 3n41 Chikungunya virus Viral 1 0 2.5 ± 2.9 71 ± 7 -5.8
3.1.07.01. Fusion peptide of E1 envelope glycoprotein (84-101) 2rsw Chikungunya virus Endosome 1 0 8.3 ± 0.6 57 ± 7 -6.9
2.2.34.02. Kappa-theraphotoxin-Pg1a 2wh9 Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 6.4 ± 1.0 57 ± 6 -9.2
2.2.34.02. Beta-theraphotoxin-Cj1a 2i1t Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.2 ± 0.7 58 ± 6 -5.8
2.2.34.02. Jingzhaotoxin-11 2a2v Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.0 ± 1.8 74 ± 19 -4.6
2.2.34.02. U1-theraphotoxin-Cj1a 2aap Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.6 ± 0.7 82 ± 5 -4.9
2.2.05.01. Plastocyanin 2plt Chlamydomonas reinhardtii Thylakoid 1 0 1.3 ± 1.5 21 ± 18 -2.0
1.1.01.01. Channelrhodopsin 2, structure 1 6eid Chlamydomonas reinhardtii Eukaryo. plasma 2 14 31.4 ± 0.8 0 ± 0 -106.6
3.1.01.04. Ferredoxin, chloroplastic, transit peptide (1-32) 1fct Chlamydomonas reinhardtii Thylakoid 1 1 21.8 ± 6.7 28 ± 4 -8.4
1.1.01.01. Chimaera of channelrhodopsins 1 and 2 3ug9 Chlamydomonas reinhardtii Eukaryo. plasma 2 14 31.0 ± 1.2 0 ± 0 -100.3
1.1.01.01. Channelrhodopsin 2, structure 2 6eig Chlamydomonas reinhardtii Eukaryo. plasma 2 14 31.4 ± 0.8 0 ± 0 -107.3
1.1.06.01. Cytochrome b6f 1q90 Chlamydomonas reinhardtii Thylakoid 16 26 31.8 ± 1.0 0 ± 1 -226.4
1.1.02.07. Bacteriochlorophyll c-binding protein, complex with chlorophyll 5lcb Chlorobium tepidum Bact. Gram-neg inner 6 0 13.0 ± 0.0 89 ± 0 -54.3
1.1.02.07. Bacteriochlorophyll c-binding protein 2k37 Chlorobium tepidum Bact. Gram-neg inner 1 0 5.8 ± 0.2 87 ± 2 -17.8
2.3.06.07. Lipase 1cvl Chromobacterium viscosum Secreted 1 0 9.9 ± 1.0 53 ± 9 -8.7
1.1.100.01. Voltage-sensor domain of phosphatase, conformation 1 4g80 Ciona intestinalis Eukaryo. plasma 1 4 29.4 ± 1.4 14 ± 1 -44.6
1.1.100.01. Voltage-sensor domain of phosphatase, conformation 2 4g7v Ciona intestinalis Eukaryo. plasma 1 4 30.2 ± 1.8 5 ± 0 -49.2
2.1.08.01. Cytochrome c6 1ls9 Cladophora glomerata Thylakoid 1 0 4.1 ± 1.0 70 ± 14 -2.9
2.1.03.01. Alpha-toxin 1olp Clostridium absonum Secreted 1 0 2.8 ± 1.8 62 ± 11 -6.1
1.1.80.01. Phospho-N-acetylmuramoyl-pentapeptide-transferase 5jnq Clostridium bolteae Bact. Gram-pos plas. 2 20 30.6 ± 1.0 3 ± 2 -133.9
2.3.19.01. Toxin B 2bvl Clostridium difficile Secreted 1 0 2.0 ± 1.1 24 ± 14 -4.2
1.1.14.02. Formate/nitrite transporter 3tdp Clostridium difficile Bact. Gram-pos plas. 5 30 28.4 ± 1.9 0 ± 0 -161.3
2.3.19.01. Toxin A 4r04 Clostridium difficile Secreted 1 0 3.2 ± 2.4 74 ± 2 -6.7
2.4.33.02. Collagenase 2y3u Clostridium histolyticum Secreted 1 0 3.0 ± 1.0 89 ± 4 -5.4
2.3.19.01. Alpha-toxin 2vk9 Clostridium novyi Secreted 1 0 3.2 ± 1.0 80 ± 2 -5.2
1.3.25.01. Necrotic enteritis toxin B, NetB 4h56 Clostridium perfringens Secreted 7 17 25.2 ± 0.8 0 ± 0 -50.7
1.3.25.01. Necrotic enteritis toxin B 4i0n Clostridium perfringens Secreted 1 0 1.6 ± 2.4 38 ± 7 -4.3
2.1.03.01. Alpha-toxin, different sequence (PHLC2_CLOPE in Uniprot) 1kho Clostridium perfringens Secreted 1 0 3.8 ± 1.0 87 ± 4 -8.2
2.1.03.01. Alpha-toxin (PHLC1_CLOPE), closed state (inactive) 1gyg Clostridium perfringens Secreted 1 0 6.1 ± 2.0 75 ± 6 -5.9
2.2.35.01. Perfringolysin 1pfo Clostridium perfringens Secreted 1 0 4.4 ± 2.0 38 ± 12 -6.7
2.1.03.01. Alpha-toxin (PHLC1_CLOPE), open state 1ca1 Clostridium perfringens Secreted 1 0 2.9 ± 1.0 89 ± 4 -9.3
2.1.03.01. Alpha-toxin (PHLC_CLOP1) 2wxu Clostridium perfringens Secreted 1 0 4.0 ± 0.9 85 ± 5 -7.0
2.1.03.01. Alpha-toxin (PHLC_CLOP1) , different conformation 1qmd Clostridium perfringens Secreted 1 0 4.8 ± 1.0 80 ± 8 -6.7
2.3.19.01. Cytotoxin L 2vkh Clostridium sordellii Secreted 1 0 1.4 ± 2.0 51 ± 17 -4.5
1.1.10.03. ABC-type bacteriocin transporter 4ry2 Clostridium thermocellum Bact. Gram-pos plas. 2 12 33.8 ± 0.2 1 ± 0 -109.4
2.2.47.01. Glycoside hydrolase family 9 protein 1wzx Clostridium thermocellum Bact. Gram-pos plas. 1 0 7.4 ± 2.0 77 ± 6 -4.1
2.3.01.08. Endoglucanase H 2vi0 Clostridium thermocellum Bact. Gram-pos plas. 1 0 1.5 ± 1.3 36 ± 9 -3.8
3.1.35.01. Cn-AMP1 peptide 2n0v Cocos nucifera Secreted 1 0 2.9 ± 1.3 73 ± 18 -2.3
2.3.06.09. Cutinase 1 3dcn Colletotrichum gloeosporioides Secreted 1 0 5.7 ± 1.2 44 ± 8 -10.1
1.1.104.01. TRIC cation channel 5wuf Colwellia psychrerythraea Bact. Gram-neg inner 3 21 30.2 ± 0.8 0 ± 0 -112.5
1.3.16.01. Anion-selective porin 2fgq Comamonas acidovorans Bact. Gram-neg outer 3 48 25.0 ± 0.9 0 ± 0 -130.8
2.2.41.02. Toxin CgNa 2h9x Condylactis gigantea (Giant Caribbean anemone) Secreted 1 0 3.6 ± 1.6 70 ± 15 -2.7
3.1.20.01. Conotoxin Ar1446 2m61 Conus araneosus Secreted 1 0 1.8 ± 0.8 82 ± 6 -4.0
3.2.02.02. Chi-conotoxin Ar1248 2m62 Conus araneosus Secreted 1 0 1.9 ± 1.0 78 ± 12 -3.0
3.1.20.01. alpha-conotoxin auIB 1dg2 Conus aulicus Secreted 1 0 5.1 ± 1.7 89 ± 16 -4.9
3.1.20.01. Alpha-conotoxin BuIA 2i28 Conus bullatus (Bubble cone) Secreted 1 0 7.4 ± 2.2 68 ± 9 -4.6
3.2.02.02. Conopeptide CnVA 3zkt Conus consors (Singed cone) Secreted 1 0 7.9 ± 2.9 88 ± 27 -5.2
3.1.20.01. Alpha-conotoxin CnIA 1b45 Conus consors (Singed cone) Secreted 1 0 0.8 ± 0.8 80 ± 20 -2.1
3.1.20.01. Alpha-conotoxin-like EpI 1a0m Conus episcopatus (Bishop's cone) Secreted 1 0 3.3 ± 1.2 58 ± 9 -3.2
3.1.20.01. Alpha-conotoxin EI 1k64 Conus ermineus Secreted 1 0 3.6 ± 1.4 78 ± 19 -3.3
2.2.34.01. Delta conotoxin EVIA 1g1z Conus ermineus Secreted 1 0 6.5 ± 1.9 72 ± 18 -8.7
3.1.20.01. Alpha-conotoxin EIVA 1pqr Conus ermineus Secreted 1 0 2.5 ± 1.3 14 ± 14 -3.4
2.2.34.01. Conotoxin muOxi-GVIIJ 2n8h Conus geographus (Geography cone) Secreted 1 0 4.0 ± 1.0 43 ± 5 -4.1
2.2.34.01. Omega-conotoxin GVIA 2cco Conus geographus (Geography cone) Secreted 1 0 4.4 ± 0.9 62 ± 7 -3.1
2.2.34.01. Mu-conotoxin GS 1ag7 Conus geographus (Geography cone) Secreted 1 0 1.9 ± 1.0 68 ± 15 -2.6
3.1.20.01. Alpha-conotoxin GIA 1not Conus geographus (Geography cone) Secreted 1 0 1.6 ± 1.5 89 ± 20 -2.3
3.1.20.01. Alpha-conotoxin GID 1mtq Conus geographus (Geography cone) Secreted 1 0 1.3 ± 2.5 78 ± 28 -2.4
2.2.34.01. Conotoxin Gm9 1ixt Conus gloriamaris (Glory-of-the-Seas cone) Secreted 1 0 1.7 ± 1.7 85 ± 17 -3.0
3.1.20.01. Alpha-conotoxin ImI 1e75 Conus imperialis (Imperial cone) Secreted 1 0 1.9 ± 0.9 80 ± 15 -3.7
3.4.01.01. Contryphan-In 2m6d Conus inscriptus Secreted 1 0 8.2 ± 1.0 57 ± 15 -5.8
3.1.20.01. Alpha4/6-conotoxin TxIC 2m3i Conus lividus Secreted 1 0 5.3 ± 1.0 77 ± 10 -4.9
3.4.01.01. Contryphan-Lo 2m6h Conus loroisii Secreted 1 0 3.3 ± 0.8 89 ± 14 -5.4
2.2.34.01. Omega-conotoxin MVIIA 1mvi Conus magus Secreted 1 0 4.7 ± 1.9 68 ± 14 -4.0
3.1.20.01. alpha-conotoxin MII 1mii Conus magus Secreted 1 0 2.7 ± 1.8 45 ± 19 -4.2
2.2.34.01. Conotoxin mr3e 2efz Conus marmoreus Secreted 1 0 1.0 ± 1.3 83 ± 25 -3.2
2.2.34.01. Mu-O conotoxin MrVIB 1rmk Conus marmoreus Secreted 1 0 10.1 ± 1.3 62 ± 19 -10.7
3.2.02.02. T-2-conotoxin MrIA 2ew4 Conus marmoreus Secreted 1 0 2.5 ± 1.5 81 ± 19 -3.0
3.2.02.02. Chi-conotoxin MrIB 1ieo Conus marmoreus Secreted 1 0 2.2 ± 1.1 45 ± 12 -1.9
3.4.06.01. Conomarphin 2jqc Conus marmoreus Secreted 1 0 4.1 ± 1.1 89 ± 12 -7.4
3.1.20.01. Alpha-conotoxin OmIA 2gcz Conus omaria (Omaria cone) Secreted 1 0 3.0 ± 1.5 62 ± 11 -3.7
3.1.20.01. alpha-conotoxin PNI1 1pen Conus pennaceus Secreted 1 0 5.2 ± 1.7 27 ± 19 -3.8
3.1.20.01. alpha-conotoxin PNIB 1akg Conus pennaceus Secreted 1 0 4.2 ± 1.4 42 ± 19 -5.9
3.1.20.01. Conotoxin pc16a 2ler Conus pictus Secreted 1 0 4.0 ± 1.0 64 ± 7 -4.1
2.2.34.01. Kappa-conotoxin PVIIA 1av3 Conus purpurascens (Purple cone) Secreted 1 0 3.4 ± 1.9 77 ± 7 -3.2
2.2.34.09. Psi-conotoxin PIIIF 1jlp Conus purpurascens (Purple cone) Secreted 1 0 2.1 ± 1.1 72 ± 30 -3.1
2.2.34.09. Psi-conotoxin PIIIE 1as5 Conus purpurascens (Purple cone) Secreted 1 0 1.9 ± 1.3 87 ± 11 -3.6
3.1.20.01. Alpha-conotoxin PIA 1zlc Conus purpurascens (Purple cone) Secreted 1 0 2.6 ± 1.3 59 ± 16 -4.3
3.1.20.01. Alpha-conotoxin PIVA 1p1p Conus purpurascens (Purple cone) Secreted 1 0 2.4 ± 1.0 30 ± 11 -3.8
3.1.34.01. Conantokin-R1-B 2mzm Conus rolani Secreted 1 0 1.9 ± 0.7 81 ± 8 -2.9
3.1.20.01. Alpha-conotoxin S1 1qmw Conus striatus Secreted 1 0 2.8 ± 2.6 43 ± 17 -2.5
2.2.34.01. Omega conotoxin SO3 1fyg Conus striatus Secreted 1 0 2.9 ± 1.1 76 ± 18 -3.5
2.2.34.01. Omega-conotoxin SVIB 1mvj Conus striatus Secreted 1 0 1.1 ± 2.1 20 ± 24 -2.1
2.2.34.01. Omega conotoxin TxVII 1f3k Conus textile Secreted 1 0 2.8 ± 1.4 57 ± 18 -4.5
2.2.34.01. Delta conotoxin TxVIA 1fu3 Conus textile Secreted 1 0 6.5 ± 1.8 25 ± 18 -8.3
2.2.34.01. Conotoxin TVIIA 1eyo Conus tulipa (Fish-hunting cone snail) Secreted 1 0 2.2 ± 0.7 74 ± 9 -4.6
3.1.20.01. Rho-conotoxin TIA 1ien Conus tulipa (Fish-hunting cone snail) Secreted 1 0 3.4 ± 1.6 73 ± 7 -3.5
3.1.20.01. Alpha-conotoxin Vc1A 2h8s Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.8 59 ± 6 -2.5
3.1.20.01. O2-contryphan-Vc2 5l34 Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.4 85 ± 8 -4.2
3.1.20.01. O2-contryphan-Vc1 2n24 Conus victoriae (Queen Victoria cone) Secreted 1 0 1.6 ± 1.0 89 ± 22 -3.6
2.4.16.13 Copsin 2mn5 Coprinopsis cinerea Secreted 1 0 3.0 ± 1.5 59 ± 9 -5.9
2.4.16.02. Coprisin 2ln4 Copris tripartitus Secreted 1 0 4.5 ± 0.6 42 ± 4 -5.3
2.1.38.01. Anion-specific porin B 2vql Corynebacterium glutamicum Bact. Gram-pos cell wall 1 0 6.2 ± 0.3 83 ± 2 -12.7
1.1.26.04. Glycine betaine transporter BetP, substrate-bound 2wit Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 30.4 ± 1.2 0 ± 0 -198.6
1.1.26.04. Glycine betaine transporter BetP, outward-open 4llh Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 29.8 ± 0.4 0 ± 0 -175.4
1.1.26.04. Glycine betaine transporter BetP, alternative inward-facing open conformation 3p03 Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 29.8 ± 0.7 1 ± 0 -160.9
1.1.26.04. Glycine betaine transporter BetP, asymmetric trimer, conformation 2 4doj Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 30.0 ± 0.6 0 ± 0 -186.4
1.1.26.04. Glycine betaine transporter BetP, inward-facing conformation 4c7r Corynebacterium glutamicum Bact. Gram-pos plas. 3 39 30.0 ± 0.7 1 ± 0 -186.7
1.1.26.04. Glycine betaine transporter BetP, asymmetric trimer, conformation 1 4ain Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 29.8 ± 0.6 0 ± 0 -198.8
2.2.06.01. Extracellular fatty acid-binding protein 2kt4 Coturnix coturnix japonica (Japanese quail) Secreted 1 0 3.9 ± 2.9 61 ± 8 -3.4
2.4.11.01. Crambin 1ejg Crambe abyssinica Secreted 1 0 4.0 ± 1.7 79 ± 15 -7.0
2.4.16.02. Defensin 2b68 Crassostrea gigas (Pacific oyster) Secreted 1 0 5.8 ± 1.7 28 ± 20 -4.0
2.1.01.01. Snake phospholipase A2, group II 1pp2 Crotalus atrox Secreted 1 0 3.7 ± 1.3 80 ± 7 -12.9
2.1.01.01. Snake phospholipase A2 crotoxin basic chain 2, group II 2qog Crotalus durissus terrificus Secreted 1 0 2.1 ± 1.1 84 ± 8 -7.2
3.1.29.01. Crotalicidin 2mwt Crotalus durissus terrificus Secreted 1 0 5.2 ± 2.4 86 ± 1 -8.6
2.2.41.05. Crotamine 1z99 Crotalus durissus terrificus Secreted 1 0 3.7 ± 0.8 26 ± 5 -5.6
2.3.06.09. Cutinase-like protein 2czq Cryptococcus sp. Secreted 1 0 4.9 ± 1.3 54 ± 16 -9.0
1.3.25.03. Hemolytic lectin CEL-III 3w9t Cucumaria echinata (Sea cucumber) Secreted 7 14 33.8 ± 0.8 0 ± 0 -82.6
2.2.05.02. Mavicyanin 1ws8 Cucurbita pepo Undefined 1 0 3.7 ± 0.5 31 ± 8 -6.5
3.1.21.07. Cupiennin-1a (M-ctenitoxin-Cs1a) 2k38 Cupiennius salei (Wandering spider) Secreted 1 0 8.1 ± 4.0 77 ± 9 -5.1
1.1.52.02. 4-amino-4-deoxy-L-arabinose transferase 5f15 Cupriavidus metallidurans Bact. Gram-neg inner 1 13 29.2 ± 0.7 3 ± 0 -93.8
2.4.32.01. Vanadium chloroperoxidase 3bb0 Curvularia inaequalis Secreted 1 0 3.8 ± 0.8 52 ± 6 -5.3
1.1.02.03. Photosystem II 4yuu Cyanidium caldarium Thylakoid 34 70 32.2 ± 0.8 0 ± 0 -411.9
1.1.36.01. ClC chloride transporter 3org Cyanidoschyzon merolae Eukaryo. plasma 2 28 28.7 ± 1.3 0 ± 2 -140.4
1.1.10.03. ATP-binding cassette, sub-family B, member 1, mutant 3wmg Cyanidoschyzon merolae Eukaryo. plasma 1 6 36.8 ± 0.3 10 ± 3 -65.5
1.1.02.02. Photosystem I-light harvesting supercomplex, structure 1 5zgh Cyanidoschyzon merolae Thylakoid 12 44 30.6 ± 0.4 3 ± 0 -291.9
1.1.02.02. Photosystem I-light harvesting supercomplex, structure 2 6fos Cyanidoschyzon merolae Thylakoid 12 44 30.2 ± 0.2 1 ± 0 -301.5
1.1.10.03. ATP-binding cassette, sub-family B, member 1 3wme Cyanidoschyzon merolae Eukaryo. plasma 2 12 35.0 ± 1.6 0 ± 0 -83.5
1.1.109.01. NADPH oxidase 5 (NOX5) 5o0t Cylindrospermum stagnale Bact. Gram-neg inner 1 6 29.4 ± 1.4 10 ± 4 -59.6
2.1.01.01. Snake phospholipase A2, group II, VRV-PL-VIIIa 1zwp Daboia russelli pulchella Secreted 1 0 4.9 ± 1.0 76 ± 7 -12.5
2.1.01.01. Snake phospholipase A2, acidic 2h4c Daboia russellii siamensis Secreted 1 0 5.7 ± 1.1 88 ± 10 -9.0
2.1.01.01. Snake phospholipase A2 RV-7, group II 1oqs Daboia russellii siamensis Secreted 1 0 2.7 ± 1.1 87 ± 8 -7.9
1.1.01.02. Lysophosphatidic acid receptor 6a 5xsz Danio rerio Eukaryo. plasma 1 7 35.0 ± 0.6 11 ± 1 -83.2
1.2.32.01. Prostaglandin I2 synthase 3b98 Danio rerio Endoplasm. reticulum 1 0 4.4 ± 1.3 65 ± 6 -4.7
1.1.10.08. Cystic fibrosis transmembrane conductance regulator, phosphorylated 5w81 Danio rerio Eukaryo. plasma 1 12 31.0 ± 1.0 6 ± 2 -82.2
1.1.15.01. Glycine receptor, alpha-1, glycine-bound state 3jae Danio rerio Eukaryo. plasma 5 20 31.8 ± 0.4 0 ± 0 -191.1
1.1.13.02. ATP-gated P2X4 ion channel, closed state 3h9v Danio rerio Eukaryo. plasma 3 6 27.6 ± 1.3 0 ± 1 -61.3
2.2.06.02. Cellular retinol-binding protein II 1kqw Danio rerio Eukaryo. plasma 1 0 3.1 ± 1.3 45 ± 13 -4.9
2.2.06.02. Fatty acid binding protein 6, ileal (Gastrotropin) 3elz Danio rerio Eukaryo. plasma 1 0 1.1 ± 0.9 85 ± 6 -2.4
1.1.15.01. Glycine receptor, alpha-1, glycine/ivermectin-bound state 3jaf Danio rerio Eukaryo. plasma 5 20 33.4 ± 1.4 0 ± 0 -180.2
1.1.102.01. STRA6 receptor, with calmodulin 5sy1 Danio rerio Eukaryo. plasma 2 18 30.8 ± 0.0 0 ± 0 -141.2
1.1.13.02. ATP-gated P2X4 ion channel, open state 4dw1 Danio rerio Eukaryo. plasma 3 6 26.8 ± 0.6 0 ± 0 -56.0
1.1.10.08. Cystic fibrosis transmembrane conductance regulator, dephosphorylated 5uar Danio rerio Endosome 1 12 30.6 ± 0.8 0 ± 0 -81.7
1.3.22.01. VDAC-2 channel 4bum Danio rerio Mitochon. outer 1 19 23.4 ± 0.9 4 ± 0 -47.7
1.2.32.01. Cytochrome P450 17A1 6b82 Danio rerio Endoplasm. reticulum 1 0 6.3 ± 1.6 48 ± 1 -23.3
1.2.32.01. Cytochrome P450 17A1 4r1z Danio rerio Endoplasm. reticulum 1 0 5.0 ± 1.2 83 ± 2 -6.5
1.2.32.01. Cytochrome P450 17A2 4r21 Danio rerio Endoplasm. reticulum 1 0 1.0 ± 10.0 70 ± 10 -2.4
1.1.117.01. Palmitoyltransferase 6bms Danio rerio Golgi 1 4 29.0 ± 2.6 10 ± 3 -42.1