PDB ID or protein name

All proteins in OPM (3809 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.1.25.03. Enterocin 7A 2m5z Enterococcus faecalis Secreted 0 0 4.4 ± 0.3 57 ± 3 -5.3
2.1.63.01. Phosphatidylinositol mannoside acyltransferase PatA 5f34 Mycobacterium smegmatis Bact. Gram-pos plas. 0 0 3.9 ± 0.5 58 ± 1 -6.9
2.3.01.09. Arabinogalactan endo-1,4-beta-galactosidase 1hjq Humicola insolens (Soft-rot fungus) Secreted 1 0 1.8 ± 1.4 86 ± 7 -3.7
1.1.44.01. Disulfide bond formation protein B, conformation 1 2k74 Escherichia coli Bact. Gram-neg inner 1 4 29.7 ± 2.4 26 ± 1 -50.2
2.4.16.01. Beta-toxin CsEI 1b3c Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.9 ± 1.2 70 ± 7 -3.9
2.4.29.01. Superantigen-like protein 3r2t Staphylococcus aureus Undefined 1 0 4.2 ± 0.0 79 ± 1 -6.2
1.3.15.01. Outer membrane protein G (OMPG), open state 1 2iwv Escherichia coli Bact. Gram-neg outer 1 14 25.3 ± 1.4 3 ± 5 -61.3
1.1.01.02. Neurotensin receptor type 1, structure 2 4buo Rattus norvegicus Eukaryo. plasma 1 7 31.4 ± 1.4 6 ± 2 -62.6
1.1.09.01. Calcium ATPase, E1-2Ca state 5mpm Sus scrofa Endoplasm. reticulum 1 10 31.0 ± 0.6 19 ± 0 -76.0
3.1.11.04. Orexin-A 1wso Homo sapiens Secreted 1 0 6.4 ± 1.7 72 ± 14 -5.5
2.2.34.06. Inhibitor cystine knot peptide MCh-1 2m2q Momordica charantia Secreted 1 0 6.9 ± 0.7 74 ± 7 -6.3
1.1.01.02. Histamine H1 receptor 3rze Homo sapiens Eukaryo. plasma 1 7 32.0 ± 1.4 1 ± 1 -72.4
1.2.09.01. Stannin 1zza Homo sapiens Mitochon. outer 1 1 30.0 ± 2.0 13 ± 2 -25.2
2.4.06.03. Class 10 plant pathogenesis-related protein 2qim Lupinus luteus Secreted 1 0 3.3 ± 1.4 41 ± 3 -3.1
1.2.04.01. Integrin beta-3, transmembrane helix 2rmz Homo sapiens Eukaryo. plasma 1 1 30.0 ± 3.6 49 ± 2 -36.0
1.1.01.02. 5-hydroxytryptamine receptor 2B, structure 2, with LSD 5tvn Homo sapiens Eukaryo. plasma 1 7 33.0 ± 2.0 18 ± 2 -68.3
1.2.41.01. Acyl-CoA-binding protein 2cb8 Homo sapiens Peroxisome 1 0 2.7 ± 2.0 74 ± 29 -5.2
2.4.16.04. Defensin 3psm Pachyrhizus erosus Secreted 1 0 4.1 ± 1.8 32 ± 8 -5.4
1.1.73.01. TrbI protein 2bhv Helicobacter pylori Bact. Gram-neg outer 1 0 3.1 ± 1.3 42 ± 11 -6.4
2.4.03.01. Tubby protein 3c5n Homo sapiens Eukaryo. plasma 1 0 3.4 ± 0.4 75 ± 5 -7.6
3.4.04.01. Daptomycin, Ca-free, different conformation 1t5m Streptomyces roseosporus Secreted 1 0 2.3 ± 1.3 33 ± 6 -7.9
1.1.26.07. STAS domain of sulfate permease 4dgf Wolinella succinogenes Bact. Gram-neg inner 1 0 2.6 ± 0.5 51 ± 2 -7.0
3.1.02.01. Cannabinoid receptor 2, TMH 6 2ki9 Homo sapiens Eukaryo. plasma 1 1 28.4 ± 2.2 21 ± 9 -17.0
1.2.39.01. Endoplasmic reticulum aminopeptidase 1 3mdj Homo sapiens Endoplasm. reticulum 1 0 1.9 ± 3.6 63 ± 10 -4.6
2.3.06.02. MPT51/MPB51 antigen 1r88 Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 1.8 ± 1.0 28 ± 26 -3.9
2.1.01.01. Basic phospholipase A2 homolog CTs-R6 4h0s Trimeresurus stejnegeri Secreted 1 0 6.0 ± 1.2 87 ± 4 -9.4
3.1.03.03. Membrane-bound helix of phosphotransferase IIA component 1o53 Escherichia coli Bact. Gram-neg inner 1 0 3.3 ± 1.3 86 ± 15 -7.8
2.2.06.02. Cellular retinol-binding protein III 1ggl Homo sapiens Eukaryo. plasma 1 0 3.3 ± 1.9 53 ± 16 -4.9
2.1.29.06. Perilipin-3 1szi Mus musculus Endosome 1 0 2.4 ± 2.3 61 ± 6 -4.1
3.2.01.03. Gomesin 1kfp Acanthoscurria gomesiana (Tarantula spider) Secreted 1 0 0.5 ± 1.0 75 ± 6 -2.7
3.1.11.02. Glucagon-like peptide-1 receptor agonists 2n08 Designed proteins Undefined 1 0 6.3 ± 1.3 45 ± 10 -5.4
1.3.19.01. Porin OpdQ 3t24 Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.0 ± 1.3 2 ± 0 -56.5
2.2.41.01. Alpha-defensin cryptdin-4 1tv0 Mus musculus Secreted 1 0 2.9 ± 1.4 67 ± 13 -4.5
3.1.28.08. Ocellatin-LB1 5u9v Leptodactylus labyrinthicus Secreted 1 0 4.7 ± 1.4 76 ± 4 -6.6
1.1.29.01. YddG transporter 5i20 Starkeya novella Bact. Gram-neg inner 1 10 30.2 ± 1.3 0 ± 0 -78.1
3.1.04.02. Major prion protein, peptide 110-136 2lbg Homo sapiens Eukaryo. plasma 1 0 5.0 ± 7.0 86 ± 1 -9.3
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3l4d Leishmania infantum Endoplasm. reticulum 1 0 8.4 ± 1.8 66 ± 9 -12.6
3.2.01.01. Arenicin-2 2jni Arenicola marina Secreted 1 0 2.1 ± 1.1 82 ± 15 -5.2
2.4.51.01. Heme acquisition protein HasA 1b2v Serratia marcescens Secreted 1 0 1.9 ± 1.6 18 ± 18 -3.3
2.2.27.01. Kinase supressor of Ras, Ksr 1kbf Mus musculus Eukaryo. plasma 1 0 1.8 ± 1.0 63 ± 11 -5.4
2.2.34.03. Toxin Ptu1 1i26 Peirates turpis (Assassin bug) Secreted 1 0 2.5 ± 0.9 52 ± 7 -3.6
3.4.07.02. Bradykinin antagonist B-9340 1bdk Designed proteins Undefined 1 0 4.4 ± 0.4 22 ± 8 -5.1
1.3.06.02. Carbapenem-associated resistance porin CarO3 4fuv Acinetobacter baumannii Bact. Gram-neg outer 1 8 25.0 ± 2.3 3 ± 1 -38.5
3.1.04.03. Viral protein R, peptide 50-82 1bde Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.8 ± 1.1 89 ± 24 -6.7
2.4.16.01. Beta-insect excitatory toxin BmKIT1 1wwn Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.2 ± 1.1 72 ± 6 -4.4
3.1.16.02. Carnobacteriocin, X component 5ujr Carnobacterium maltaromaticum Secreted 1 0 5.4 ± 3.0 89 ± 13 -11.9
2.2.07.01. Lipocalin BcnA 5ixh Burkholderia cepacia Bact. Gram-neg inner 1 0 1.4 ± 2.6 28 ± 29 -1.7
1.2.32.01. Steroid 21-hydroxylase (P450 C21) 3qz1 Bos taurus Endoplasm. reticulum 1 0 5.9 ± 1.6 72 ± 3 -10.4
2.1.26.01. Colicin A channel-forming domain 1col Escherichia coli Secreted 1 0 1.8 ± 1.0 43 ± 11 -3.2
3.1.28.05. Peptoid analogue of maculatin 2mmj Litoria genimaculata Secreted 1 0 10.0 ± 4.6 73 ± 3 -13.1
2.2.20.01. Oxysterol binding protein-related protein 11 2d9x Homo sapiens Eukaryo. plasma 1 0 1.4 ± 1.7 55 ± 18 -3.1
1.3.02.01. Opacity protein opA60, structure 1 2maf Neisseria gonorrhoeae Bact. Gram-neg outer 1 8 23.8 ± 1.0 20 ± 1 -34.2
1.2.38.01. Monofunctional glycosyltransferase 3vmr Staphylococcus aureus Bact. Gram-pos plas. 1 1 30.8 ± 1.2 25 ± 2 -35.4
2.1.01.01. Snake phospholipase A2, group I, isoform 3 3jql Naja sagittifera Secreted 1 0 6.2 ± 1.0 85 ± 5 -7.0
2.2.34.13. Nemertide alpha-1 toxin 6ena Lineus longissimus Secreted 1 0 4.0 ± 1.6 85 ± 9 -6.8
2.2.53.01. Fas apoptotic inhibitory molecule 1 3mx7 Homo sapiens Eukaryo. plasma 1 0 4.2 ± 1.4 16 ± 13 -7.1
1.2.32.01. Cytochrome P450 2B4, closed state 2 2q6n Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.5 ± 0.4 55 ± 2 -13.0
2.2.34.01. Omega conotoxin SO3 1fyg Conus striatus Secreted 1 0 2.9 ± 1.1 76 ± 18 -3.5
3.2.01.01. Arenicin-1 2jsb Arenicola marina Secreted 1 0 2.4 ± 2.1 80 ± 11 -5.2
2.3.06.11. Monoglyceride lipase MGLL, open conformation 2 6bq0 Homo sapiens Eukaryo. plasma 1 0 8.5 ± 2.0 12 ± 4 -12.6
2.2.34.02. Hybrid atracotoxin 2h1z Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 0.6 ± 2.0 82 ± 20 -1.9
1.1.01.01. Sensory rhodopsin, monomer 1xio Nostoc sp. Bact. Gram-neg inner 1 7 31.9 ± 1.5 13 ± 4 -63.1
1.3.17.02. BamABCDE complex, structure 1 5ayw Escherichia coli Bact. Gram-neg outer 1 16 22.8 ± 1.2 7 ± 0 -57.5
1.1.26.07. STAS domain of prestin 3llo Rattus norvegicus Eukaryo. plasma 1 0 5.4 ± 0.6 68 ± 4 -5.3
1.1.30.01. Membrane protein insertase YidC 2 3wo7 Bacillus halodurans Bact. Gram-pos plas. 1 5 29.0 ± 1.3 12 ± 0 -58.2
2.2.34.11. Leaf cyclotide 2 2kuk Viola hederacea Secreted 1 0 3.4 ± 1.2 83 ± 20 -5.9
2.3.06.04. Palmitoyl protein thioesterase 1 1eh5 Bos taurus Lysosome 1 0 5.3 ± 0.9 59 ± 6 -8.1
1.1.116.01. Glycerol-3-phosphate acyltransferase, structure 1 5xj5 Aquifex aeolicus Bact. Gram-neg inner 1 7 28.2 ± 2.0 16 ± 1 -53.7
2.2.20.01. Fermitin family homolog 2 4f7h Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.4 72 ± 4 -4.2
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form, mutant 4os0 Homo sapiens Endoplasm. reticulum 1 0 2.4 ± 1.0 77 ± 4 -3.1
2.2.30.01. Nawaprin 1udk Naja nigricollis Secreted 1 0 6.3 ± 1.0 81 ± 8 -7.3
2.1.44.01. Bacteriocin ASM1 2mvi Lactobacillus plantarum Secreted 1 0 5.3 ± 1.4 33 ± 5 -4.9
1.1.01.02. C-X-C chemokine receptor type 4, inactive, complex with antagonist 3oe6 Homo sapiens Eukaryo. plasma 1 7 35.3 ± 2.5 8 ± 7 -79.7
1.1.34.01. Mitochondrial uncoupling protein 2 2lck Mus musculus Mitochon. inner 1 6 30.0 ± 1.2 12 ± 1 -30.3
3.1.07.05. Nonstructural protein 4b, segment 1716-1755 2lvg Hepatitis C virus Viral 1 0 6.4 ± 0.7 82 ± 8 -11.4
1.3.17.02. Outer membrane protein assembly factor BamA 5or1 Salmonella typhimurium Bact. Gram-neg outer 1 16 24.2 ± 0.8 9 ± 2 -53.7
2.2.06.01. Extracellular fatty acid-binding protein 2kt4 Coturnix coturnix japonica (Japanese quail) Secreted 1 0 3.9 ± 2.9 61 ± 8 -3.4
1.2.32.01. Cytochrome P450 2B4, closed state, mutant 5iut Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.3 ± 0.5 56 ± 2 -13.0
2.3.06.06. Triacylglycerol lipase, open (active) state 1ein Humicola lanuginosa Secreted 1 0 8.1 ± 0.8 63 ± 4 -14.5
3.2.05.02. Chaxapeptin 1 2n5c Streptomyces leeuwenhoekii Secreted 1 0 7.2 ± 1.0 82 ± 9 -8.8
1.2.32.01. Cytochrome P450 4B1 5t6q Oryctolagus cuniculus Endoplasm. reticulum 1 0 8.8 ± 0.6 38 ± 2 -17.0
2.3.06.07. Lipase L1, isoform 1 1ji3 Bacillus stearothermophilus Secreted 1 0 3.5 ± 1.7 22 ± 10 -8.0
2.4.16.04. Defensin-like protein 32 2mz0 Arabidopsis thaliana Secreted 1 0 2.6 ± 1.4 19 ± 8 -3.4
1.1.25.05. Bacterial proton:oligopeptide symporter, structure 3 4tpj Shewanella oneidensis Bact. Gram-neg inner 1 14 30.6 ± 0.9 9 ± 0 -90.0
1.2.43.01. Envelope glycoprotein, Zika virus, structure 6 5gzn Zika virus Viral 1 0 5.1 ± 2.6 41 ± 11 -4.9
1.1.44.01. Disulfide bond formation protein B, conformation 3 2zuq Escherichia coli Bact. Gram-neg inner 1 4 27.9 ± 3.1 27 ± 1 -36.6
2.1.18.01. Annexin GH1 1n00 Gossypium hirsutum Eukaryo. plasma 1 0 1.5 ± 2.0 70 ± 17 -3.7
2.4.25.01. N-alpha-acetyltransferase 60, structure 1 5hgz Homo sapiens Golgi 1 0 5.7 ± 1.1 41 ± 7 -8.5
2.4.16.01. Toxin BmKaIT1 1omy Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.0 ± 1.3 83 ± 10 -3.8
2.3.28.01. Aldo-keto reductase family 1 member C21 3fjn Mus musculus Undefined 1 0 2.8 ± 1.0 56 ± 3 -5.2
1.3.20.01. Outer membrane cobalamin transporter BtuB, meso form 2guf Escherichia coli Bact. Gram-neg outer 1 22 23.4 ± 0.9 6 ± 7 -69.3
2.1.60.02. Potassium channel blocking domain of matrix metalloproteinase-23 2k72 Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 2.3 77 ± 22 -4.4
3.1.20.01. alpha-conotoxin MII 1mii Conus magus Secreted 1 0 2.7 ± 1.8 45 ± 19 -4.2
2.2.20.01. Pleckstrin homology domain-containing family A member 5 (PLEKHA5) 2dkp Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.9 64 ± 6 -3.9
3.1.11.02. Glucagon analog, lipidated 2m5p Homo sapiens Secreted 1 0 5.2 ± 0.6 85 ± 4 -6.0
2.2.20.01. Dual adaptor of phosphotyrosine and 3-phosphoinositides 1fao Homo sapiens Eukaryo. plasma 1 0 2.4 ± 2.0 59 ± 19 -3.9
2.2.06.02. Retinol-binding protein 1 5h9a Homo sapiens Eukaryo. plasma 1 0 3.3 ± 0.9 59 ± 4 -5.7
3.1.24.01. Penaeidin-3a 1ueo Litopenaeus vannamei (Whiteleg shrimp) Secreted 1 0 1.3 ± 3.5 89 ± 2 -5.5
2.4.11.01. Crambin, enantiomer 3ue7 Designed proteins Undefined 1 0 3.4 ± 1.7 89 ± 13 -4.6
1.2.30.01. Potassium voltage-gated channel subfamily E member 2 2m0q Homo sapiens Eukaryo. plasma 1 1 31.8 ± 3.9 34 ± 5 -31.8
2.3.06.01. Bile-salt activated lipase, conformation 2 1akn Bos taurus Secreted 1 0 3.8 ± 1.5 77 ± 15 -6.7
2.4.34.01. Ice-structuring protein 4ur4 Zoarces viviparus Secreted 1 0 3.2 ± 4.1 68 ± 2 -5.8
1.2.32.01. Cytochrome P450 2C9, structure 2 1r9o Homo sapiens Endoplasm. reticulum 1 0 4.0 ± 1.1 59 ± 8 -10.1
2.4.16.02. Drosomycin 1myn Drosophila melanogaster Secreted 1 0 4.6 ± 1.2 10 ± 17 -6.0
3.2.09.03. Tyrocidine A 4m6e Bacillus brevis Secreted 1 0 6.8 ± 0.9 56 ± 8 -9.0
2.3.06.01. Acetylcholinesterase 1n5m Mus musculus Eukaryo. plasma 1 0 3.7 ± 1.3 28 ± 6 -6.1
1.1.01.04. Smoothened homolog, monomer, structure 5 5v56 Homo sapiens Eukaryo. plasma 1 7 30.2 ± 1.8 12 ± 3 -60.3
1.2.46.01. Agnoprotein (17-52) 2mj2 JC polyomavirus Endosome 1 1 22.0 ± 2.0 25 ± 3 -15.0
2.4.16.08. Hydramacin-1 2k35 Hydra vulgaris Secreted 1 0 2.0 ± 0.2 87 ± 2 -4.3
3.2.10.01. PawS derived peptide 9 2nb5 Designed proteins Undefined 1 0 5.6 ± 1.3 79 ± 14 -6.5
2.3.16.02. Translocation ATPase SecA 1tf5 Bacillus subtilis Bact. Gram-pos plas. 1 0 2.5 ± 1.1 64 ± 5 -7.0
2.1.29.01. Apolipoprotein A-I 2a01 Homo sapiens Secreted 1 0 4.8 ± 1.2 63 ± 11 -6.5
2.3.25.02. Phospholipase A1 4hyq Streptomyces albidoflavus Secreted 1 0 1.4 ± 1.4 31 ± 7 -3.9
1.2.03.03. Myelin protein P0 3oai Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.2 72 ± 6 -5.8
1.2.32.01. Cholesterol 7-alpha-monooxygenase (P450 7A1) 3dax Homo sapiens Endoplasm. reticulum 1 0 1.8 ± 1.9 69 ± 8 -3.9
2.1.01.01. Myotoxin 1s8i Agkistrodon contortrix laticinctus Secreted 1 0 4.9 ± 0.7 83 ± 5 -10.6
2.1.62.01. Thuricin beta 2la0 Bacillus cereus Secreted 1 0 10.0 ± 2.6 37 ± 7 -8.8
2.3.32.01. UDP-N-acetylmuramate--L-alanine ligase 1p31 Haemophilus influenzae Bact. Gram-neg inner 1 0 4.4 ± 1.8 29 ± 14 -4.6
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1uw5 Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.5 18 ± 16 -5.4
1.1.12.15. TRPV6 channel, monomer, structure 1 5wo9 Rattus norvegicus Eukaryo. plasma 1 6 30.2 ± 1.0 20 ± 0 -86.5
3.1.03.02. Serine/threonine-protein kinase TOR1, FATC domain 2kit Saccharomyces cerevisiae Vacuole 1 0 6.3 ± 1.0 87 ± 18 -6.4
3.1.15.04. Bacteriocin plantaricin J (PlnJ) 2khg Lactobacillus plantarum Secreted 1 0 5.4 ± 4.0 72 ± 2 -9.0
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2w5q Staphylococcus aureus Bact. Gram-pos plas. 1 0 0.4 ± 3.6 82 ± 11 -2.5
2.3.06.07. Triacylglycerol lipase 2w22 Geobacillus thermocatenulatus Secreted 1 0 5.6 ± 0.0 86 ± 0 -22.4
1.2.50.01. Sticholysin II 1gwy Stoichactis helianthus Secreted 1 0 3.4 ± 1.9 35 ± 15 -5.0
3.2.05.01. Sviceucin 2ls1 Streptomyces sviceus Secreted 1 0 2.6 ± 1.3 78 ± 5 -7.0
2.4.06.02. Phosphatidylinositol transfer protein beta isoform 2a1l Rattus norvegicus Eukaryo. plasma 1 0 4.7 ± 1.7 36 ± 17 -4.3
1.1.01.03. Glucagon receptor, full-length, structure 2 5yqz Homo sapiens Eukaryo. plasma 1 7 28.6 ± 1.6 13 ± 1 -51.9
2.2.11.01. Synaptotagmin-7 3n5a Mus musculus Vesicle 1 0 2.2 ± 2.3 30 ± 12 -4.1
2.2.34.09. Psi-conotoxin PIIIF 1jlp Conus purpurascens (Purple cone) Secreted 1 0 2.1 ± 1.1 72 ± 30 -3.1
1.3.15.02. CymA protein, conformation 2 4d5b Klebsiella oxytoca Bact. Gram-neg outer 1 14 23.4 ± 1.0 3 ± 1 -48.7
1.1.01.02. Type-1 angiotensin II receptor 4yay Homo sapiens Eukaryo. plasma 1 7 35.8 ± 0.4 13 ± 1 -71.0
2.1.01.01. Myotoxin II 2aoz Atropoides nummifer Secreted 1 0 3.4 ± 0.7 80 ± 3 -11.8
3.1.11.02. Thp5 peptide 2lma Mus musculus Secreted 1 0 5.8 ± 3.4 83 ± 5 -7.2
1.1.01.02. Adenosine receptor A2a, complex with antibody 3vga Homo sapiens Eukaryo. plasma 1 7 30.4 ± 1.4 7 ± 2 -62.8
2.4.13.01. Oxysterol-binding protein homolog 3 4ic4 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 4.3 ± 0.9 86 ± 29 -5.9
2.2.34.02. Hanatoxin 1 1d1h Grammostola rosea (Chilean rose tarantula) Secreted 1 0 3.4 ± 1.7 68 ± 15 -4.2
2.3.06.07. Lipase I.3, open state 3a70 Pseudomonas sp. Secreted 1 0 9.1 ± 1.0 58 ± 1 -32.9
2.3.14.01. Neurofibromin 2d4q Homo sapiens Eukaryo. plasma 1 0 1.6 ± 2.0 34 ± 19 -3.3
3.1.07.01. Fusion peptide (524-539) of ebolavirus glycoprotein GP2 2rlj Zaire ebolavirus Viral 1 0 5.8 ± 1.8 84 ± 6 -6.8
3.1.20.01. Alpha-conotoxin-like EpI 1a0m Conus episcopatus (Bishop's cone) Secreted 1 0 3.3 ± 1.2 58 ± 9 -3.2
2.1.08.01. Cytochrome c552 1a8c Nitrosomonas europaea Bact. Gram-neg inner 1 0 2.7 ± 1.0 80 ± 11 -4.7
1.3.20.01. Ferredoxin receptor FusA 4zgv Pectobacterium atrosepticum Bact. Gram-neg outer 1 22 23.6 ± 0.7 7 ± 0 -65.8
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 2 4nc9 Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 4.1 ± 1.1 69 ± 7 -7.9
3.2.01.04. Retrocyclin-2 (HTD-2) 2atg Macaca mulatta Secreted 1 0 2.4 ± 0.6 87 ± 9 -5.6
2.1.24.01. Saposin A (peptide 60-140), conformation in disc 4ddj Homo sapiens Lysosome 1 0 6.4 ± 0.9 89 ± 3 -8.5
1.1.01.02. C-X-C chemokine receptor type 1 2lnl Homo sapiens Eukaryo. plasma 1 7 30.2 ± 0.9 19 ± 6 -54.4
2.2.41.01. Beta-defensin 8 1e4r Mus musculus Secreted 1 0 2.8 ± 1.1 74 ± 19 -5.5
3.1.14.01. Tachykinin-4 2moc Homo sapiens Secreted 1 0 4.6 ± 0.6 75 ± 5 -7.7
2.1.18.01. Annexin IV 2zoc Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.1 82 ± 7 -7.6
2.1.20.01. Osteocalcin 1q8h Sus scrofa Secreted 1 0 2.3 ± 1.7 81 ± 17 -4.4
3.1.02.11. Methyl-accepting chemotaxis protein II 2l9g Escherichia coli Bact. Gram-neg inner 1 0 8.1 ± 4.2 75 ± 0 -11.7
1.2.03.05. Cytokine receptor common subunit beta (432-473) 2na8 Homo sapiens Eukaryo. plasma 1 1 34.0 ± 2.8 22 ± 2 -32.9
1.1.01.02. C-C chemokine receptor type 5 4mbs Homo sapiens Eukaryo. plasma 1 7 34.4 ± 1.5 0 ± 0 -88.8
2.3.16.06. ADP-ribosylation factor 1 (ARF1) 2k5u Saccharomyces cerevisiae Golgi 1 0 2.9 ± 1.6 24 ± 18 -5.5
3.1.13.01. Calcitonin 1bku Anguilla japonica (Japanese eel) Secreted 1 0 3.0 ± 0.4 77 ± 3 -8.7
2.1.24.01. Pore-forming peptide ameobapore A 1of9 Entamoeba histolytica Undefined 1 0 1.5 ± 1.0 13 ± 18 -2.3
1.3.19.02. Alginate export protein, AlgE, conformation 1 3rbh Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.4 ± 1.2 4 ± 0 -72.0
1.2.17.01. Syntaxin 1A, pre-fusion structure in micelles 2m8r Rattus norvegicus Eukaryo. plasma 1 2 20.8 ± 0.5 8 ± 5 -20.5
1.1.113.01. ERAD-associated E3 ubiquitin-protein ligase component HRD3 5v7v Saccharomyces cerevisiae Endoplasm. reticulum 1 0 8.3 ± 2.6 75 ± 3 -18.6
3.1.21.08. Moricin 1x22 Spodoptera litura Secreted 1 0 4.4 ± 1.1 70 ± 5 -9.2
2.3.06.09. Cutinase 5ajh Fusarium oxysporum Secreted 1 0 6.2 ± 0.3 25 ± 9 -7.6
2.3.06.13. Protein Ndr1 2xmr Homo sapiens Eukaryo. plasma 1 0 8.2 ± 2.6 50 ± 10 -8.8
2.3.003.01. Gamma-ketol reductase 5a3v Arabidopsis thaliana Chloroplast inner 1 0 5.0 ± 0.6 89 ± 4 -8.9
2.1.57.01. Adhesin FadA 3etw Fusobacterium nucleatum Secreted 1 0 5.0 ± 3.8 47 ± 5 -6.7
2.3.10.02. Beta-1,2-glucuronosyltrnansferase GumK 2q6v Xanthomonas campestris Bact. Gram-neg inner 1 0 5.2 ± 1.0 61 ± 8 -9.5
1.1.01.02. C-C chemokine receptor type 2 5t1a Homo sapiens Eukaryo. plasma 1 7 32.6 ± 1.4 3 ± 2 -80.2
2.3.06.12. Gibberellin receptor GID1A 2zsh Arabidopsis thaliana Nuclear inner 1 0 2.6 ± 1.2 89 ± 6 -5.0
2.4.16.05. Plectasin 3e7r Pseudoplectania nigrella (Ebony cup) Secreted 1 0 2.7 ± 2.3 53 ± 17 -4.0
1.3.20.01. Outer membrane receptor FauA 3efm Bordetella pertussis Bact. Gram-neg outer 1 22 24.7 ± 0.6 11 ± 0 -77.5
2.2.27.01. RAS guanyl-releasing protein 1 4l9m Homo sapiens Eukaryo. plasma 1 0 5.3 ± 1.3 24 ± 3 -7.8
2.2.05.01. Plastocyanin 1bxv Synechocystis sp. Thylakoid 1 0 2.0 ± 1.6 36 ± 19 -2.6
3.2.05.01. Siamycin II (tricyclic peptide RP71935) 1rpb Streptomyces sp. Secreted 1 0 4.2 ± 1.3 85 ± 15 -8.3
2.4.51.01. Heme acquisition protein HasA 4xzd Yersinia pseudotuberculosis Secreted 1 0 3.5 ± 0.4 25 ± 2 -5.9
1.2.04.01. Integrin beta-3, 742-788, in micelles 1s4x Homo sapiens Eukaryo. plasma 1 0 6.9 ± 1.0 18 ± 10 -5.8
1.2.32.01. Cytochrome P450 3A4, conformation 1 1tqn Homo sapiens Endoplasm. reticulum 1 0 8.7 ± 1.0 67 ± 11 -18.5
1.2.22.01. Apoptosis regulator BAX 1f16 Homo sapiens Mitochon. outer 1 0 4.3 ± 0.8 84 ± 5 -4.2
2.3.06.07. Thermostable lipase 4fdm Bacillus sp. Secreted 1 0 5.2 ± 0.6 28 ± 2 -8.5
1.1.60.01. Protease GlpG, complex with inhibitor, conformation 1 2xow Escherichia coli Bact. Gram-neg inner 1 6 29.0 ± 1.7 15 ± 2 -59.0
2.2.06.02. Intestinal fatty acid binding protein, structure 1 1kzw Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.3 61 ± 12 -4.1
1.1.01.06. Adiponectin receptor 1, open 5lxg Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.0 21 ± 0 -68.3
2.4.07.01. Nischarin 3p0c Homo sapiens Endosome 1 0 4.1 ± 0.5 82 ± 13 -7.0
3.1.21.06. Stomoxyn 1zrx Stomoxys calcitrans (Stable fly) Secreted 1 0 5.7 ± 0.0 80 ± 0 -12.3
3.2.10.01. PawS derived peptide 7 2lwu Designed proteins Undefined 1 0 2.0 ± 1.4 81 ± 10 -3.0
1.3.19.01. Outer membrane porin OpdL 2y0h Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.0 ± 1.0 3 ± 0 -55.7
2.2.39.01. Cytotoxin-1 1rl5 Naja naja oxiana Secreted 1 0 5.2 ± 2.0 51 ± 16 -5.7
3.1.19.01. Bergofungin A 5mas Emericellopsis donezkii Secreted 1 1 30.8 ± 1.5 35 ± 20 -13.2
2.3.16.06. ADP-ribosylation factor-like protein 1 2x77 Leishmania major Eukaryo. plasma 1 0 1.6 ± 1.4 80 ± 5 -3.6
1.1.09.01. Calcium ATPase, E2-Pi state, conformation 3 3b9b Oryctolagus cuniculus Endoplasm. reticulum 1 10 29.9 ± 1.6 16 ± 2 -58.1
1.1.01.01. Green-light absorbing proteorhodopsin 2l6x Gamma-proteobacterium Bact. Gram-neg inner 1 7 27.8 ± 1.3 18 ± 1 -55.2
1.1.01.02. C-C chemokine receptor type 5, with chemokine 5uiw Homo sapiens Eukaryo. plasma 1 7 31.8 ± 2.4 8 ± 1 -84.8
3.1.07.01. Fusion peptide of spike glycoprotein (983-887) 2ruo Human SARS coronavirus Endosome 1 0 9.9 ± 4.0 72 ± 6 -9.0
3.1.21.01. Papiliocin 2la2 Papilio xuthus Secreted 1 0 7.8 ± 2.0 62 ± 4 -7.4
2.2.41.01. Chimeric beta-defensin 2/3 2lxo Designed proteins Undefined 1 0 3.6 ± 0.8 56 ± 14 -5.6
1.2.44.01. Amyloid beta A4 protein (peptide 672-711), in water 2lfm Homo sapiens Eukaryo. plasma 1 0 5.3 ± 0.5 87 ± 4 -8.6
2.3.10.04. Teichoic acid biosynthesis protein TagF 3l7l Staphylococcus epidermidis Bact. Gram-pos plas. 1 0 6.9 ± 2.0 35 ± 15 -10.8
2.3.06.06. Lipase 2ory Photbacterium lipolyticum Secreted 1 0 6.3 ± 1.1 62 ± 10 -12.0
3.1.21.11. HYL-20 peptide 5mmk Hylaeus signatus Secreted 1 0 4.9 ± 2.8 81 ± 8 -8.8
1.2.39.01. Endoplasmic reticulum aminopeptidase 2 3se6 Homo sapiens Endoplasm. reticulum 1 0 2.5 ± 1.8 60 ± 21 -4.5
2.1.01.01. Snake phospholipase A2-3, group II 1gmz Bothrops pirajai Secreted 1 0 3.8 ± 1.5 88 ± 10 -6.7
3.2.04.01. Cyclic trypsin inhibitor STFI-1 1jbl Helianthus annuus Secreted 1 0 7.2 ± 0.8 72 ± 8 -6.1
2.2.07.01. Acidic stress response factor 3hpe Helicobacter pylori Bact. Gram-neg inner 1 0 3.0 ± 0.7 34 ± 8 -6.1
3.1.33.01. Stage V sporulation protein M 2mvh Bacillus subtilis Vacuole 1 0 6.3 ± 1.0 90 ± 4 -9.9
3.1.14.01. Neuropeptide K 2b19 Homo sapiens Secreted 1 0 5.1 ± 4.3 46 ± 8 -5.7
1.1.30.01. YidC-like protein 5c8j Methanococcus jannaschii Archaebac. 1 4 29.8 ± 1.4 42 ± 2 -42.1
1.3.11.01. Diffuse adherence adhesin 4mee Escherichia coli Bact. Gram-neg outer 1 12 26.4 ± 2.4 5 ± 1 -46.6
2.1.25.02. Carnocyclin A 2kjf Carnobacterium maltaromaticum Secreted 1 0 2.1 ± 1.1 61 ± 12 -4.6
2.4.16.03. Potassium channel toxin gamma-KTx 2.2 6au7 Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.2 ± 1.6 78 ± 11 -3.4
2.3.16.07. Ras-related C3 botulinum toxin substrate 1 2p2l Homo sapiens Eukaryo. plasma 1 0 3.2 ± 0.8 58 ± 2 -5.2
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 6 2zbe Oryctolagus cuniculus Endoplasm. reticulum 1 10 28.0 ± 0.7 16 ± 0 -55.4
2.3.06.08. Phospholipase A1 4qnn Vespa basalis Secreted 1 0 3.5 ± 0.5 64 ± 2 -11.1
2.2.39.01. Cytotoxin 4 4om5 Naja atra Secreted 1 0 3.8 ± 0.6 75 ± 3 -11.1
1.1.38.01. Na+/drug antiporter NorM, outward-open, structure 1 4hum Neisseria gonorrhoeae Bact. Gram-neg inner 1 12 28.6 ± 1.1 5 ± 1 -54.5
1.1.01.02. 5-hydroxytryptamine receptor 1B, structure 3 5v54 Homo sapiens Eukaryo. plasma 1 7 33.0 ± 1.4 13 ± 0 -67.8
2.2.11.01. Synaptotagmin 1, C2B domain 5vfg Mus musculus Vesicle 1 0 1.6 ± 2.0 38 ± 11 -3.6
2.2.34.02. U5-theraphotoxin-Hh1a 1qk7 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 6.3 ± 0.5 47 ± 2 -5.2
1.2.49.01. Tumor necrosis factor receptor 12A 2kmz Homo sapiens Eukaryo. plasma 1 0 5.9 ± 1.6 66 ± 3 -6.3
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase, another loop disordered 4ff6 Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 3.4 ± 1.5 19 ± 6 -6.4
2.2.34.11. Cycloviolacin-O2 2kcg Viola odorata Secreted 1 0 5.1 ± 2.9 58 ± 36 -6.8
3.2.05.02. Klebsidin 5ui7 Klebsiella pneumoniae Secreted 1 0 2.5 ± 1.4 62 ± 11 -3.7
2.1.02.01. Arachidonate 5-lipoxygenase, complex with arachidonic acid 3v99 Homo sapiens Eukaryo. plasma 1 0 3.0 ± 2.3 88 ± 9 -2.5
2.4.16.01. LQH III alpha-like toxin 1fh3 Leiurus quinquestriatus hebraeus Secreted 1 0 3.6 ± 1.5 83 ± 16 -5.2
1.1.25.06. D-xylose-proton symporter xylE, conformation 3 4ja4 Escherichia coli Bact. Gram-neg inner 1 12 28.2 ± 1.3 0 ± 0 -82.8
2.2.02.01. Mitochondrial serine protease HtrA2 1lcy Homo sapiens Mitochon. inner 1 0 7.4 ± 1.8 67 ± 14 -5.1
3.1.12.01. Sarafotoxin-B 1srb Atractaspis engaddensis (Israeli burrowing asp) Secreted 1 0 4.9 ± 1.9 62 ± 10 -4.1
2.2.05.01. Azurin iso-2 1cuo Methylomonas sp. Bact. Gram-neg inner 1 0 1.4 ± 1.6 69 ± 15 -4.3
1.1.01.02. Muscarinic acetylcholine receptor M1 5cxv Homo sapiens Eukaryo. plasma 1 7 32.8 ± 0.7 4 ± 0 -78.2
2.3.06.06. Lipase A, closed state 3guu Candida antarctica Secreted 1 0 4.4 ± 1.0 80 ± 2 -10.9
1.3.02.01. Outer membrane protein NspA 1p4t Neisseria meningitidis Bact. Gram-neg outer 1 8 24.9 ± 2.4 22 ± 3 -42.9
1.1.01.02. Rhodopsin, inactive, structure 3 1u19 Bos taurus Eukaryo. plasma 1 7 31.2 ± 1.5 12 ± 1 -71.9
2.2.06.01. Neutrophil gelatinase-associated lipocalin 3fw5 Homo sapiens Secreted 1 0 2.0 ± 1.2 45 ± 9 -3.1
2.3.06.12. Carboxylesterase 3wj2 Thermoplasma acidophilum Secreted 1 0 2.9 ± 1.9 81 ± 9 -5.1
2.2.11.01. Rabphilin-3A, C2B domain 2cm5 Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 2.0 56 ± 14 -4.1
1.1.69.01. HIG1 domain family member 1A 2lom Homo sapiens Mitochon. inner 1 2 22.0 ± 5.0 1 ± 1 -27.3
1.2.43.01. Envelope glycoprotein, Dengue virus type 3 1uzg Dengue virus Viral 1 0 5.7 ± 2.7 18 ± 7 -5.4
2.2.11.01. Synaptotagmin-1, C2A domain (Calcium bound) 1byn Rattus norvegicus Eukaryo. plasma 1 0 3.8 ± 1.6 32 ± 19 -4.7
1.1.01.02. Endothelin B receptor, with endothelin 5glh Homo sapiens Eukaryo. plasma 1 7 34.8 ± 1.0 6 ± 1 -81.5
2.2.12.03. Immunogenic protein MPT63 1lmi Mycobacterium tuberculosis Secreted 1 0 2.2 ± 1.9 86 ± 7 -4.3
1.2.39.03. Disintegrin and metalloproteinase domain-containing protein 10 2ao7 Bos taurus Golgi 1 0 3.1 ± 1.4 81 ± 6 -5.7
2.4.16.01. Toxin CsEv1 1vna Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.9 ± 1.0 65 ± 10 -7.8
2.1.48.01. Glycerol dehydrogenase 1kq3 Thermotoga maritima Undefined 1 0 2.5 ± 1.8 80 ± 5 -4.3
1.3.15.01. Outer membrane protein G (OMPG), closed state 2iww Escherichia coli Bact. Gram-neg outer 1 14 24.7 ± 1.4 6 ± 4 -63.3
1.2.04.01. Integrin alpha-L, transmembrane helix (1082-1128) 2m3e Homo sapiens Eukaryo. plasma 1 1 29.8 ± 5.6 30 ± 17 -25.9
1.1.53.01. RAS methyltransferase ICMT 5v7p Tribolium castaneum Endoplasm. reticulum 1 8 29.8 ± 1.2 14 ± 0 -72.4
3.1.21.05. Poneratoxin 1g92 Paraponera clavata Secreted 1 0 22.8 ± 8.5 29 ± 7 -12.9
2.2.34.07. Asteropsin B 2lzx Asteropus sp. Secreted 1 0 2.2 ± 1.7 90 ± 21 -3.3
2.2.06.02. Fatty acid-binding protein 2k62 Gallus gallus Eukaryo. plasma 1 0 0.0 ± 2.9 82 ± 13 -2.0
1.2.22.01. Activator of apoptosis harakiri, transmembrane helix 2l5b Homo sapiens Mitochon. outer 1 1 29.8 ± 0.9 14 ± 11 -11.9
2.4.42.01. Cholesteryl ester transfer protein 2obd Homo sapiens Secreted 1 0 7.4 ± 2.9 26 ± 6 -7.0
2.4.35.01. 8R-Lipoxygenase, N-terminal domain 1u5u Plexaura homomalla Eukaryo. plasma 1 0 3.1 ± 0.3 72 ± 3 -10.4
1.1.01.02. Adenosine receptor A2a, with triazole-carboximidamide antagonist 5uig Homo sapiens Eukaryo. plasma 1 7 30.6 ± 1.4 13 ± 4 -62.6
1.2.41.01. Acyl-CoA-binding domain-containing protein 4 2wh5 Homo sapiens Peroxisome 1 0 7.2 ± 2.4 77 ± 26 -5.7
2.4.16.04. Defensin 1ti5 Vigna radiata (Mung bean) Secreted 1 0 1.9 ± 2.4 62 ± 16 -3.0
2.3.27.01. Dihydrofolate reductase 3nzb Pneumocystis carinii Undefined 1 0 3.9 ± 1.9 72 ± 10 -5.9
1.3.12.01. Outer membrane phospholipase A, monomer 1qd5 Escherichia coli Bact. Gram-neg outer 1 12 24.6 ± 1.2 6 ± 0 -52.6
2.1.03.01. Alpha-toxin, different sequence (PHLC2_CLOPE in Uniprot) 1kho Clostridium perfringens Secreted 1 0 3.8 ± 1.0 87 ± 4 -8.2
3.1.21.04. Spiderine-1a 2n85 Oxyopes takobius (Lynx spider) Secreted 1 0 3.2 ± 4.2 88 ± 0 -7.8
1.2.01.01. Receptor tyrosine kinase erbB-2 1iij Rattus norvegicus Eukaryo. plasma 1 1 31.8 ± 2.8 27 ± 2 -31.8
1.2.32.01. Cytochrome P450 2B4, open state 2 1po5 Oryctolagus cuniculus Endoplasm. reticulum 1 0 3.5 ± 1.4 79 ± 9 -7.2
3.1.05.03. Peptide YW12 2o0s Designed proteins Bact. Gram-pos cell wall 1 0 3.4 ± 1.3 82 ± 5 -5.5
2.1.01.01. MTX-II chain A 4k06 Bothrops brazili Secreted 1 0 5.0 ± 1.3 60 ± 11 -7.1
2.3.06.05. Carboxylesterase 2 1auo Pseudomonas fluorescens Bact. Gram-neg inner 1 0 1.7 ± 3.0 33 ± 21 -3.4
2.2.06.02. Retinoid-binding protein 7 1lpj Homo sapiens Eukaryo. plasma 1 0 2.6 ± 1.1 44 ± 13 -6.0
2.2.29.01. Multivesicular body subunit 12B 3tow Homo sapiens Endosome 1 0 4.5 ± 2.3 33 ± 22 -5.8
3.2.01.03. Polyphemusin-1 1rkk Limulus polyphemus (Atlantic horseshoe crab) Secreted 1 0 3.5 ± 3.7 63 ± 11 -4.0
3.1.05.13. Cullin3-derived peptides 2myl Designed proteins Undefined 1 0 3.4 ± 1.2 82 ± 21 -4.4
1.1.59.01. Membrane protease specific for a stomatin homolog, monomer 3bpp Pyrococcus horikoshii Archaebac. 1 0 4.0 ± 0.4 82 ± 5 -6.3
1.3.20.01. Transferrin-binding protein A, complex with human serotransferrin 3v89 Neisseria meningitidis Bact. Gram-neg outer 1 22 22.8 ± 0.8 3 ± 1 -68.9
2.2.20.01. Rho guanine nucleotide exchange factor 9, conformation 1 4mt7 Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 2.6 52 ± 14 -3.9
1.1.08.01. F0 ATP synthase, subunit c 1wu0 Bacillus ps3 Bact. Gram-pos plas. 1 2 31.9 ± 2.7 44 ± 1 -23.2
2.2.41.01. Alpha-defensin 4 1zmm Homo sapiens Secreted 1 0 2.2 ± 1.0 76 ± 10 -5.5
3.1.28.08. Ocellatin-LB2 5ua7 Leptodactylus labyrinthicus Secreted 1 0 7.0 ± 4.4 78 ± 2 -11.1
1.1.39.01. Riboflavin transporter RibU 5kbw Thermotoga maritima Bact. Gram-neg inner 1 6 32.4 ± 1.6 8 ± 1 -52.7
3.1.04.02. Major prion protein, peptide 173-195 2iv5 Homo sapiens Eukaryo. plasma 1 0 5.3 ± 4.1 83 ± 17 -3.5
3.1.19.01. Zervamicin IIb, transmembrane orientation 1r9u Emericellopsis salmosynnemata Secreted 1 1 23.2 ± 5.4 38 ± 7 -15.0
2.4.51.01. Heme acquisition protein HasA, different strain 3wah Pseudomonas aeruginosa Secreted 1 0 3.4 ± 0.6 14 ± 3 -5.1
2.1.07.01. Nonaheme cytochrome c 1duw Desulfovibrio desulfuricans Bact. Gram-neg inner 1 0 5.1 ± 0.4 87 ± 10 -4.9
2.2.27.01. RAF-1 proto-oncogene serine/threonine-protein kinase 1faq Homo sapiens Eukaryo. plasma 1 0 4.8 ± 1.1 30 ± 14 -7.3
2.4.16.10. Toxin MIT1 (Black mamba intestinal toxin 1) 1imt Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 4.8 ± 0.7 70 ± 3 -9.1
3.2.07.01. N-terminal beta-hairpin of ubiquitin 1e0q Bos taurus Undefined 1 0 3.5 ± 0.4 85 ± 0 -7.8
1.1.38.01. H+-driven MATE exporter, outward-open, different conformation 4mlb Pyrococcus furiosus Archaebac. 1 12 30.2 ± 1.2 5 ± 0 -88.1
1.3.19.02. Alginate export protein, AlgE, conformation 3 4b61 Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 24.0 ± 1.1 5 ± 1 -73.2
3.1.07.10. Structural peptide 1 of bursal disease virus 2imu Avian infectious bursal disease virus Eukaryo. plasma 1 0 11.6 ± 4.0 76 ± 5 -17.5
2.2.34.02. Psalmotoxin-1 1lmm Psalmopoeus cambridgei (Trinidad chevron tarantula) Secreted 1 0 2.4 ± 1.6 71 ± 15 -4.4
3.1.16.02. Carnobacteriocin, Y component 5ujq Carnobacterium maltaromaticum Secreted 1 0 8.3 ± 3.0 57 ± 4 -9.3
2.3.16.08. Interferon-inducible GTPase 1 1tpz Mus musculus Endoplasm. reticulum 1 0 2.5 ± 2.0 37 ± 7 -5.0
2.1.27.01. Cry3Bb1 1ji6 Bacillus thuringiensis Secreted 1 0 3.8 ± 1.6 64 ± 6 -4.2
3.4.08.03. Oxytocin 1xy2 Bos taurus Secreted 1 0 2.1 ± 2.6 86 ± 12 -3.2
2.3.16.06. ADP-ribosylation factor-like protein 2, complex with human PDEdelta 1ksg Mus musculus Eukaryo. plasma 1 0 6.9 ± 1.7 77 ± 15 -5.7
2.4.10.01. Synapsin I 1auv Bos taurus Vesicle 1 0 1.9 ± 1.1 86 ± 11 -5.2
2.1.29.03. Cholesteryl ester transfer inhibitor protein 1eze Papio hamadryas (Hamadryas baboon) Secreted 1 0 4.6 ± 0.2 89 ± 3 -9.9
3.1.02.01. Peptide 171-197 of parathyroid hormone receptor 1bl1 Homo sapiens Eukaryo. plasma 1 1 20.8 ± 1.2 19 ± 4 -11.5
2.1.01.01. Snake phospholipase A2 homolog 1, group II 2ok9 Bothrops pirajai Secreted 1 0 3.5 ± 1.4 76 ± 7 -7.6
3.2.04.04. Barrettide A 6cfb Geodia barretti Secreted 1 0 3.3 ± 0.8 90 ± 9 -4.7
1.2.32.01. Cytochrome P450 2B4, closed state 3 3g5n Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.7 ± 1.8 65 ± 3 -12.1
2.2.34.01. Delta conotoxin EVIA 1g1z Conus ermineus Secreted 1 0 6.5 ± 1.9 72 ± 18 -8.7
3.2.03.01. Hepcidin, structure 1 3h0t Homo sapiens Secreted 1 0 4.7 ± 0.6 82 ± 9 -7.0
3.1.02.02. S4-3 voltage sensor peptide of calcium channel subunit alpha-1B (1242-1269) 2lcm Homo sapiens Eukaryo. plasma 1 0 2.7 ± 3.2 68 ± 6 -3.9
2.2.34.02. Kappa-hexatoxin-Hv1c 1dl0 Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 1.7 ± 1.3 53 ± 17 -3.1
1.3.20.01. Outer membrane receptor PiuA 5fok Pseudomonas aeruginosa Bact. Gram-neg outer 1 22 23.4 ± 1.1 3 ± 1 -65.9
2.2.34.11. Leaf cyclotide 1 1za8 Viola hederacea Secreted 1 0 4.9 ± 1.3 48 ± 24 -8.5
2.3.06.04. Palmitoyl protein thioesterase 2 1pja Homo sapiens Lysosome 1 0 3.7 ± 1.6 60 ± 15 -4.6
1.1.116.01. Glycerol-3-phosphate acyltransferase, structure 2 5xj6 Aquifex aeolicus Bact. Gram-neg inner 1 7 26.2 ± 2.0 9 ± 1 -57.4
1.2.44.01. Amyloid beta A4 protein, peptide 686-726 2llm Homo sapiens Eukaryo. plasma 1 1 32.8 ± 2.2 30 ± 0 -30.8
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 8 4c0c Trypanosoma cruzi Endoplasm. reticulum 1 0 9.4 ± 1.9 64 ± 7 -10.9
2.2.39.01. Cytotoxin 1 ( Cardiotoxin gamma) 1tgx Naja mossambica pallida Secreted 1 0 6.7 ± 1.0 59 ± 12 -10.0
2.1.42.01. Mundticin KS immunity protein 2zrr Enterococcus mundtii Secreted 1 0 1.6 ± 1.5 72 ± 9 -3.2
2.3.18.01. Carnitine O-palmitoyltransferase 2 2h4t Rattus norvegicus Mitochon. inner 1 0 4.0 ± 1.2 67 ± 10 -9.4
3.1.07.02. Membrane proximal external helix of HIV-1 gp41 (656-683) 2m8o Human immunodeficiency virus type 1 Viral 1 0 6.0 ± 5.2 90 ± 4 -5.0
3.1.11.02. Glucagon-like peptide 2 2l64 Homo sapiens Secreted 1 0 3.9 ± 0.3 90 ± 5 -10.8
2.3.10.01. Peptidoglycan biosynthesis glycosyltransferase MurG, conformation 2 1f0k Escherichia coli Bact. Gram-neg inner 1 0 5.3 ± 1.2 55 ± 7 -8.6
1.3.20.01. Siderophore receptor PiuD 5nec Pseudomonas aeruginosa Bact. Gram-neg outer 1 22 24.2 ± 0.8 7 ± 0 -72.9
1.1.26.01. Sodium-dependent serotonin transporter, outward-facing state 5i6x Homo sapiens Eukaryo. plasma 1 12 31.6 ± 1.4 10 ± 0 -90.7
3.1.13.01. Islet amyloid polypeptide, fragment 34-70, alternative structure 2l86 Homo sapiens Secreted 1 0 6.2 ± 0.8 88 ± 7 -9.6
1.1.01.03. Corticotropin-releasing factor receptor 1, structure 1 4k5y Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.1 16 ± 3 -71.4
2.3.06.06. Triacylglycerol lipase 1lgy Rhizopus niveus Secreted 1 0 1.9 ± 1.8 33 ± 16 -4.8
3.1.29.01. Crotalicidin 2mwt Crotalus durissus terrificus Secreted 1 0 5.2 ± 2.4 86 ± 1 -8.6
2.3.06.11. Monoglyceride lipase MGLL, open conformation 1 3jw8 Homo sapiens Eukaryo. plasma 1 0 8.1 ± 1.3 11 ± 9 -11.3
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), structure 1 5tz1 Candida albicans Endoplasm. reticulum 1 0 8.7 ± 0.9 67 ± 4 -16.2
2.3.06.08. Pancreatic lipase 1gpl Cavia porcellus Secreted 1 0 5.8 ± 1.0 86 ± 9 -7.8
2.3.09.01. Cytidylyltransferase, first membrane-anchoring helix 1peh Rattus norvegicus Eukaryo. plasma 1 0 3.2 ± 0.6 90 ± 2 -5.0
3.1.07.02. Membrane proximal peptide of gp41 (95-121) 2ncs Human immunodeficiency virus type 1 Viral 1 0 20.8 ± 2.0 28 ± 3 -14.6
2.2.57.01. Levansucrase 1w18 Gluconacetobacter diazotrophicus (Acetobacter diazotrophicus) Secreted 1 0 3.4 ± 1.6 57 ± 3 -7.2
2.3.05.03. Glycerol-3-phosphate dehydrogenase (GlpD) 2qcu Escherichia coli Bact. Gram-neg inner 1 0 4.5 ± 1.5 74 ± 11 -8.4
2.1.02.01. Arachidonate 15-lipoxygenase 2p0m Oryctolagus cuniculus Eukaryo. plasma 1 0 8.6 ± 0.1 87 ± 5 -14.3
1.1.105.01. CD81 antigen 5tcx Homo sapiens Eukaryo. plasma 1 4 34.2 ± 2.4 1 ± 1 -55.9
2.4.25.01. N-alpha-acetyltransferase 60, structure 2 5hh0 Homo sapiens Golgi 1 0 5.2 ± 0.0 46 ± 1 -10.7
2.4.16.01. Toxin Bmka2 2kbj Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.1 ± 1.5 64 ± 15 -3.6
2.3.22.01. Uncharacterized protein 1rtt Pseudomonas aeruginosa Undefined 1 0 3.1 ± 2.5 70 ± 22 -4.1
1.3.14.01. Toluene transporter TbuX 3bry Ralstonia pickettii Bact. Gram-neg outer 1 14 25.4 ± 1.5 1 ± 2 -57.7
2.2.14.01. C2 domain of coagulation factor VIII 4mo3 Sus scrofa Eukaryo. plasma 1 0 3.7 ± 0.6 19 ± 4 -9.7
1.1.79.01. P7 protein (781-809) 2k8j Hepatitis C virus Endoplasm. reticulum 1 1 23.6 ± 5.4 41 ± 4 -16.2
3.1.20.01. alpha-conotoxin auIB 1dg2 Conus aulicus Secreted 1 0 5.1 ± 1.7 89 ± 16 -4.9
3.1.18.02. Phenol-soluble modulin alpha 3 peptide 5kgy Staphylococcus aureus Secreted 1 0 9.4 ± 1.0 73 ± 7 -17.3
2.2.20.01. Rho guanine nucleotide exchange factor 4 2dx1 Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.2 80 ± 10 -3.6
2.1.60.01. Potassium channel toxin Bgk 1bgk Bunodosoma granulifera Secreted 1 0 1.8 ± 1.7 19 ± 27 -2.9
2.2.20.01. PH domain of TAPP1 1eaz Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.6 87 ± 14 -3.0
1.1.10.08. Multidrug resistance protein 1 (MRP1), structure 1 5uj9 Bos taurus Eukaryo. plasma 1 17 31.0 ± 0.2 7 ± 0 -110.7
2.4.07.01. PX domain of sorting nexin GRD19, ligand-free 1ocs Saccharomyces cerevisiae Endosome 1 0 2.5 ± 1.1 88 ± 11 -5.4
3.1.24.01. Penaeidin-4d 1xv3 Litopenaeus setiferus (Atlantic white shrimp) Secreted 1 0 3.4 ± 2.7 76 ± 17 -7.8
3.1.05.03. LAK160-P10 2l99 Designed proteins Undefined 1 0 3.9 ± 2.6 84 ± 0 -5.0
2.2.23.01. Lipoprotein BamB, conformation 1 3prw Escherichia coli Bact. Gram-neg outer 1 0 5.1 ± 1.2 81 ± 7 -8.5
1.1.10.03. ATP-binding cassette, sub-family B, member 1, mutant 3wmg Cyanidoschyzon merolae Eukaryo. plasma 1 6 36.8 ± 0.3 10 ± 3 -65.5
2.3.06.06. Lipase 1, closed (inactive) state 1trh Candida rugosa Secreted 1 0 4.9 ± 1.3 85 ± 7 -7.4
2.2.17.01. 6.5 kDa glycine-rich antifreeze protein 2pne Hypogastrura harveyi Secreted 1 0 1.7 ± 0.2 89 ± 5 -7.7
1.1.38.01. Multidrug transporter MatE 4z3n Escherichia coli Bact. Gram-neg inner 1 12 29.6 ± 1.1 7 ± 1 -93.1
2.1.40.01. Protein unc-13 homolog A, MHD domain 3swh Rattus norvegicus Eukaryo. plasma 1 0 6.6 ± 3.0 27 ± 12 -6.8
1.2.32.01. Cytochrome P450 2C5, different conformation 1dt6 Oryctolagus cuniculus Endoplasm. reticulum 1 0 7.3 ± 1.0 13 ± 7 -8.8
2.1.29.03. Apolipoprotein C-I, peptide 1-38 1opp Homo sapiens Secreted 1 0 3.6 ± 0.2 87 ± 2 -10.9
1.1.01.04. Smoothened homolog, monomer, structure 6 5v57 Homo sapiens Eukaryo. plasma 1 7 29.8 ± 1.0 20 ± 1 -60.7
3.1.21.07. Cupiennin-1a (M-ctenitoxin-Cs1a) 2k38 Cupiennius salei (Wandering spider) Secreted 1 0 8.1 ± 4.0 77 ± 9 -5.1
3.2.01.07. Transthyretin-derived peptide 5hpp Designed proteins Undefined 1 0 2.7 ± 1.6 83 ± 6 -5.2
1.3.20.01. Fe-regulated protein B, different variant 4aiq Neisseria meningitidis Bact. Gram-neg outer 1 22 23.6 ± 0.9 6 ± 0 -69.7
2.4.01.01. Cholesterol oxidase 1b4v Streptomyces sp. Bact. Gram-pos plas. 1 0 5.4 ± 0.6 39 ± 4 -8.4
2.4.16.05. Micasin 2lr5 Arthroderma otae Secreted 1 0 8.3 ± 0.6 58 ± 6 -7.8
2.3.25.02. Lipolytic protein 4rw0 Veillonella parvula Secreted 1 0 0.7 ± 0.7 60 ± 5 -4.0
1.2.03.03. Myelin protein P0 1neu Rattus norvegicus Eukaryo. plasma 1 0 5.4 ± 1.8 70 ± 8 -6.6
1.2.32.01. Cytochrome P450 1B1 3pm0 Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 0.7 79 ± 1 -7.0
2.1.01.01. Snake phospholipase A2, group I 1ae7 Notechis scutatus scutatus (Mainland tiger snake) Secreted 1 0 4.7 ± 0.6 84 ± 9 -6.2
2.1.62.01. Thuricin 17 2lbz Bacillus cereus Secreted 1 0 3.4 ± 2.6 88 ± 0 -7.7
1.1.01.02. Adenosine receptor A2a, inactive state, engineered, complex with inverse agonist 3pwh Homo sapiens Eukaryo. plasma 1 7 31.0 ± 1.3 9 ± 0 -67.3
1.1.041.02. Bidirectional sugar transporter SWEET13 5xpd Arabidopsis thaliana Eukaryo. plasma 1 7 31.4 ± 1.0 4 ± 1 -73.0
3.1.02.04. V-type proton ATPase subunit a, vacuolar isoform, TMH 7 2jtw Saccharomyces cerevisiae Vacuole 1 1 20.8 ± 6.5 8 ± 7 -7.7
3.1.01.02. Leader peptide of bacteriocin microcin B17 2mlp Escherichia coli Secreted 1 0 3.2 ± 3.6 84 ± 4 -6.6
2.4.06.05. Thermoacidophile-specific fatty acid carrier 3w9k Sulfolobus tokodaii Archaebac. 1 0 2.7 ± 1.4 47 ± 4 -7.1
2.3.16.07. Ras-related protein Rab-5C 4kyi Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.4 73 ± 1 -6.0
1.1.75.02. Sec-independent protein translocase TatA 2l16 Bacillus subtilis Bact. Gram-pos plas. 1 1 27.6 ± 2.9 10 ± 1 -27.9
2.1.01.04. Phospholipase A2 homolog 2wg7 Oryza sativa (Rice) Secreted 1 0 4.0 ± 1.1 77 ± 3 -10.7
2.3.25.01. Acyloxyacyl hydrolase, structure 1 5w7e Mus musculus Secreted 1 0 7.6 ± 0.8 82 ± 3 -4.9
1.2.01.01. Receptor tyrosine-protein kinase erbB-3, extracellular domains 1m6b Homo sapiens Eukaryo. plasma 1 0 2.0 ± 1.6 45 ± 5 -3.9
1.1.70.01. CaaX Protease Ste24p 4il3 Saccharomyces mikatae Endoplasm. reticulum 1 7 29.8 ± 1.4 8 ± 0 -63.3
2.2.22.01. Hydrophobin II 1r2m Hypocrea jecorina Secreted 1 0 4.1 ± 1.0 16 ± 15 -6.6
3.2.05.02. Caulosegnin I 2lx6 Caulobacter segnis Secreted 1 0 2.9 ± 0.8 15 ± 5 -6.0
2.1.02.01. 12S-Lipoxygenase 3d3l Homo sapiens Eukaryo. plasma 1 0 5.0 ± 0.6 51 ± 3 -9.0
1.1.01.02. Opioid kappa receptor, monomer 6b73 Homo sapiens Eukaryo. plasma 1 7 33.0 ± 2.0 10 ± 1 -77.6
2.2.12.04. AP-2 complex 2vj0 Rattus norvegicus Vesicle 1 0 2.6 ± 2.0 80 ± 11 -4.8
2.2.34.09. Psi-conotoxin PIIIE 1as5 Conus purpurascens (Purple cone) Secreted 1 0 1.9 ± 1.3 87 ± 11 -3.6
1.3.15.02. CymA protein, conformation 3 4v3g Klebsiella oxytoca Bact. Gram-neg outer 1 14 23.4 ± 1.5 3 ± 3 -45.0
2.1.01.01. Snake phospholipase A2 homolog zhaoermiatoxin, group II 2ph4 Zhaoermia manqshanensis Secreted 1 0 4.8 ± 0.8 86 ± 5 -9.2
3.2.01.03. Toxin AbTx 2m6j Sparassidae Secreted 1 0 0.8 ± 3.6 89 ± 6 -3.0
2.4.14.01. 1-acyl-sn-glycerol-3-phosphate acyltransferase 5kym Thermotoga maritima Bact. Gram-neg inner 1 0 20.2 ± 1.0 28 ± 2 -32.3
2.1.04.01. Fatty acid alpha-oxidase 4kvl Oryza sativa (Rice) Endoplasm. reticulum 1 0 5.5 ± 0.7 90 ± 1 -19.0
2.2.34.02. Voltage sensor toxin VSTx1 1s6x Grammostola rosea (Chilean rose tarantula) Secreted 1 0 4.4 ± 1.4 79 ± 13 -6.3
3.2.01.05. Protegrin-2 2muh Sus scrofa Secreted 1 0 2.1 ± 3.3 88 ± 2 -3.2
1.1.60.01. Protease GlpG, complex with inhibitor, conformation 3 3ubb Escherichia coli Bact. Gram-neg inner 1 6 29.8 ± 1.3 21 ± 1 -65.3
2.2.42.01. Matrix protein 2vqp Human respiratory syncytial virus Eukaryo. plasma 1 0 2.9 ± 1.1 86 ± 10 -6.1
3.1.07.03. Hemagglutinin, fusion peptide 346-365, G13A 2l4g Influenza virus Viral 1 0 11.1 ± 0.4 73 ± 4 -10.4
3.1.20.01. Alpha-conotoxin BuIA 2i28 Conus bullatus (Bubble cone) Secreted 1 0 7.4 ± 2.2 68 ± 9 -4.6
2.1.08.01. Cytochrome c2 1co6 Rhodopseudomonas viridis Bact. Gram-neg inner 1 0 1.4 ± 0.7 78 ± 10 -3.3
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 3 4n9w Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 5.6 ± 1.2 84 ± 3 -4.6
3.1.28.05. Aurein 1.2 1vm5 Litoria aurea Secreted 1 0 9.5 ± 1.8 63 ± 14 -9.7
2.3.10.06. Glycosyltransferase PglH (WlaC) 6eji Campylobacter jejuni Bact. Gram-neg inner 1 0 5.6 ± 1.6 49 ± 1 -15.6
2.2.41.01. Beta-defensin 12 1bnb Bos taurus Secreted 1 0 6.0 ± 1.6 88 ± 15 -10.8
3.1.34.01. Conantokin-R1-B 2mzm Conus rolani Secreted 1 0 1.9 ± 0.7 81 ± 8 -2.9
1.2.28.01. Transmembrane regulatory peptide MgtR 2mc7 Salmonella enterica Bact. Gram-neg inner 1 1 31.8 ± 2.2 13 ± 4 -26.8
2.1.18.01. Annexin VI 1avc Bos taurus Eukaryo. plasma 1 0 4.4 ± 1.0 83 ± 1 -8.1
2.2.39.01. Bucandin 1f94 Bungarus candidus (Malayan krait) Secreted 1 0 5.0 ± 1.3 61 ± 6 -4.9
1.1.25.03. Multidrug transporter EmrD 2gfp Escherichia coli Bact. Gram-neg inner 1 12 31.6 ± 1.5 9 ± 0 -58.0
1.3.25.02. Hemolysin 1xez Vibrio cholerae Secreted 1 0 8.2 ± 2.3 19 ± 6 -6.0
3.4.07.01. Antimicrobial cationic cyclic hexapeptide 1qvl Designed proteins Undefined 1 0 4.2 ± 1.6 84 ± 15 -6.8
1.1.01.02. Endothelin B receptor, structure 1 5gli Homo sapiens Eukaryo. plasma 1 7 33.6 ± 1.4 11 ± 0 -77.6
2.4.07.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Homo sapiens Golgi 1 0 2.5 ± 1.3 56 ± 16 -4.8
3.1.28.02. Alyteserin-1C 2l5r Alytes obstetricans Secreted 1 0 8.7 ± 4.1 81 ± 0 -14.1
3.1.07.03. Antimicrobial peptide derived from hemagglutinin 2l24 Influenza virus Undefined 1 0 8.7 ± 1.3 75 ± 10 -12.6
1.2.54.01. Dihydroorotate dehydrogenase 1f76 Escherichia coli Bact. Gram-neg outer 1 0 3.7 ± 0.8 24 ± 8 -8.7
1.1.01.02. Muscarinic acetylcholine receptor M2, active 4mqs Homo sapiens Eukaryo. plasma 1 7 32.2 ± 2.1 8 ± 3 -70.0
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 5tl8 Naegleria fowleri Endoplasm. reticulum 1 0 6.2 ± 1.2 64 ± 3 -9.7
3.1.14.01. Kassinin 1myu Kassina senegalensis Secreted 1 0 3.4 ± 1.5 59 ± 16 -4.5
2.3.06.06. Mono- and diacylglycerol lipase 5ch8 Penicillium cyclopium Secreted 1 0 2.7 ± 0.3 9 ± 7 -4.2
1.1.60.01. Protease GlpG, complex with peptide-based inhibitor 4qo2 Escherichia coli Bact. Gram-neg inner 1 6 28.6 ± 1.2 18 ± 0 -58.3
2.1.10.01. Glycolipid transfer protein Het-c2 3kv0 Podospora anserina Eukaryo. plasma 1 0 8.3 ± 1.3 83 ± 5 -13.6
2.2.51.01. 25 kDa protein elicitor 3gnz Pythium aphanidermatum Secreted 1 0 5.7 ± 2.5 77 ± 13 -5.1
2.3.10.03. Heptosyltransferase WaaC 2h1h Escherichia coli Bact. Gram-neg inner 1 0 5.0 ± 1.1 67 ± 5 -9.1
2.2.11.01. Protein kinase C epsilon 1gmi Rattus rattus Eukaryo. plasma 1 0 2.9 ± 1.2 46 ± 15 -5.9
2.2.09.04. Nucleoporin NUP120 3f7f Saccharomyces cerevisiae Nuclear inner 1 0 9.3 ± 2.1 66 ± 5 -11.0
2.4.16.02. Defensin heliomicin 1i2u Heliothis virescens (Tobacco budworm moth) Secreted 1 0 3.4 ± 0.4 59 ± 1 -7.6
2.3.13.04. Glutathione peroxidase-like protein 2vup Trypanosoma brucei Undefined 1 0 3.0 ± 1.7 84 ± 7 -4.1
1.3.20.01. Outer membrane heme transporter ShuA 3fhh Shigella dysenteriae Bact. Gram-neg outer 1 22 24.6 ± 0.9 5 ± 0 -70.7
2.2.27.01. Rac GTPase-activating protein 1 4b6d Homo sapiens Eukaryo. plasma 1 0 3.5 ± 0.9 55 ± 4 -5.9
2.2.05.01. Plastocyanin 1b3i Prochlorothrix hollandica Thylakoid 1 0 2.8 ± 1.4 43 ± 18 -4.4
3.2.09.02. Gramicidin S 1tk2 Bacillus brevis Secreted 1 0 8.5 ± 1.7 86 ± 21 -8.6
2.4.51.01. Heme acquisition protein HasA, dimer 4y4s Yersinia pseudotuberculosis Secreted 1 0 1.8 ± 1.1 83 ± 9 -4.2
2.3.10.07. Lipopolysaccharide biosynthesis protein RfaG, 103-131 2n58 Escherichia coli Bact. Gram-neg inner 1 0 4.5 ± 1.1 64 ± 7 -6.3
1.2.04.01. Integrin beta-3, 742-788, 747pY, in micelles 2ljd Homo sapiens Eukaryo. plasma 1 0 8.1 ± 0.6 44 ± 4 -7.6
1.2.32.01. Cytochrome P450 2A6 1z10 Homo sapiens Endoplasm. reticulum 1 0 5.0 ± 1.7 44 ± 18 -9.5
1.3.22.01. VDAC-1 channel, structure 3 (NMR) 5jdp Homo sapiens Mitochon. outer 1 19 22.4 ± 1.0 8 ± 1 -43.5
2.3.06.07. Lipase 46 kDa form 2hih Staphylococcus hyicus Secreted 1 0 4.6 ± 0.3 83 ± 1 -16.0
1.1.38.01. Na+/drug antiporter NorM, outward-open 3mkt Vibrio cholerae Bact. Gram-neg inner 1 12 29.8 ± 1.1 9 ± 0 -74.0
2.2.06.02. Brain fatty acid binding protein 1fdq Homo sapiens Eukaryo. plasma 1 0 3.1 ± 1.4 51 ± 15 -4.9
1.1.01.06. Adiponectin receptor 2 5lwy Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.4 16 ± 0 -78.0
3.1.07.01. Fusion peptide (512-541) of protein gp41 2ari Human immunodeficiency virus type 1 Endosome 1 0 10.0 ± 1.0 88 ± 9 -16.1
2.4.16.07. Diapause-specific peptide 2e2f Gastrophysa atrocyanea (Leaf beetle) Secreted 1 0 1.3 ± 1.0 30 ± 10 -4.2
3.1.05.03. LAK160-P7 2l96 Designed proteins Undefined 1 0 1.4 ± 0.9 88 ± 5 -2.7
1.3.19.01. Pyroglutamate porin OpdO 2y0k Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.8 ± 1.2 1 ± 0 -55.8
1.1.01.05. Metabotropic glutamate receptor 5 4oo9 Homo sapiens Eukaryo. plasma 1 7 32.4 ± 1.2 2 ± 1 -66.3
2.2.39.01. alpha-Cobratoxin 1ctx Naja kaouthia Secreted 1 0 2.8 ± 1.7 29 ± 18 -4.6
3.1.28.08. Ocellatin-K1 5u9x Leptodactylus knudseni Secreted 1 0 7.4 ± 0.2 77 ± 4 -11.8
2.3.16.06. ADP-ribosylation factor-like protein 5A 1z6y Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.9 66 ± 15 -4.0
1.2.32.01. Cytochrome P450 2E1 3e6i Homo sapiens Endoplasm. reticulum 1 0 8.3 ± 2.0 49 ± 8 -14.2
1.1.48.01. Putative sulfate permease CysZ 3tx3 Idiomarina loihiensis Bact. Gram-neg inner 1 6 29.8 ± 0.6 17 ± 4 -49.5
1.1.25.06. Phosphate transporter 4j05 Acanthamoeba culbertsoni Eukaryo. plasma 1 12 30.0 ± 0.5 14 ± 0 -84.2
3.1.07.01. Fusion peptide (683-704) of protein gp41 2mg1 Human immunodeficiency virus type 1 Endosome 1 1 30.8 ± 0.5 19 ± 3 -19.4
2.1.43.01. Acanthaporin 2lrd Acanthamoeba culbertsoni Secreted 1 0 4.8 ± 3.0 56 ± 26 -4.9
3.2.11.01. Peptide NC_cEE_D1 5kx2 Designed proteins Undefined 1 0 4.9 ± 1.9 70 ± 14 -4.6
1.2.44.01. Amyloid beta A4 protein (peptide 672-699) 1amb Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 87 ± 0 -3.2
1.1.26.02. Sodium-hydantoin transporter Mhp1, inward-facing conformation 2x79 Mycobacterium liquefaciens Bact. Gram-pos plas. 1 12 30.7 ± 1.1 13 ± 0 -85.0
2.3.06.07. Lipase I.3, closed state 2z8x Pseudomonas sp. Secreted 1 0 6.8 ± 1.7 74 ± 6 -8.2
2.2.34.02. Mu-theraphotoxin-Pn3a 5t4r Theraphosidae Secreted 1 0 2.9 ± 0.8 87 ± 5 -4.5
2.4.03.01. Tubby protein homolog 1s31 Homo sapiens Eukaryo. plasma 1 0 6.8 ± 1.0 71 ± 2 -7.6
1.2.32.01. Cytochrome P450 17A1, structure 1 3swz Homo sapiens Endoplasm. reticulum 1 0 4.2 ± 1.6 56 ± 3 -8.4
2.1.01.01. Snake phospholipase A2, group I 1ozy Micropechis ikaheka Secreted 1 0 2.6 ± 1.0 85 ± 5 -9.0
3.2.04.02. Bowman-Birk type proteinase inhibitor peptide 1gm2 Macrotyloma axillare Secreted 1 0 2.0 ± 1.9 59 ± 14 -3.5
2.2.07.01. Protein yceI 1y0g Escherichia coli Bact. Gram-neg inner 1 0 4.2 ± 1.5 24 ± 16 -2.1
1.1.01.02. Rhodopsin, partially active, photobleached 2i37 Bos taurus Eukaryo. plasma 1 7 31.9 ± 1.5 5 ± 1 -79.1
1.1.38.01. MATE protein 14 5y50 Arabidopsis thaliana Eukaryo. plasma 1 12 32.2 ± 1.4 5 ± 2 -74.8
3.1.11.02. Vasoactive intestinal peptide 2rrh Homo sapiens Secreted 1 0 4.1 ± 0.3 79 ± 9 -5.7
1.1.01.01. Bacteriorhodopsin-I 4wav Haloquadratum walsbyi Archaebac. 1 7 30.0 ± 2.1 9 ± 3 -63.0
1.3.02.01. Opacity protein opA60, structure 2 2mlh Neisseria gonorrhoeae Bact. Gram-neg outer 1 8 23.2 ± 2.7 13 ± 2 -30.2
3.1.11.02. Extendin-4, variant 5niq Heloderma suspectum Secreted 1 0 1.8 ± 0.8 82 ± 18 -4.4
2.3.05.05. RabGDI protein 3p1w Plasmodium falciparum Eukaryo. plasma 1 0 6.6 ± 1.4 47 ± 3 -6.8
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 8 2zbg Oryctolagus cuniculus Endoplasm. reticulum 1 10 30.0 ± 1.7 21 ± 0 -66.5
3.1.28.07. Hylin-A1 2n0o Hypsiboas albopunctatus Secreted 1 0 11.4 ± 0.8 62 ± 4 -15.4
2.1.60.03. Pseudechetoxin 2dda Pseudechis australis Secreted 1 0 4.5 ± 2.8 89 ± 7 -4.3
1.1.10.04. P-glycoprotein, human-mouse chimeric, structure 1 6fn1 Homo sapiens Eukaryo. plasma 1 12 31.0 ± 0.8 9 ± 0 -89.8
2.2.34.02. Mu-theraphotoxin-Hhn1b 1niy Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.2 ± 0.7 71 ± 6 -4.6
1.3.17.02. BamA domains 3efc Escherichia coli Bact. Gram-neg outer 1 0 4.2 ± 2.2 85 ± 9 -5.5
1.1.25.06. Glucose transporter GLUT3/SLC2A3, outward-occluded 4zw9 Homo sapiens Eukaryo. plasma 1 12 32.8 ± 1.4 6 ± 1 -95.1
2.2.34.11. Kalata-B7 2jwm Oldenlandia affinis Secreted 1 0 2.7 ± 2.2 86 ± 28 -4.8
3.2.05.02. Sphaericin 5gvo Planomonospora sphaerica Secreted 1 0 7.9 ± 3.6 31 ± 13 -11.0
1.1.01.02. Opioid delta receptor 4ej4 Mus musculus Eukaryo. plasma 1 7 34.4 ± 0.8 11 ± 6 -73.2
2.4.16.03. Charybdotoxin 2crd Leiurus quinquestriatus hebraeus Secreted 1 0 1.1 ± 1.5 86 ± 15 -3.2
3.4.08.04. Met-enkephalin 1plw Homo sapiens Secreted 1 0 4.9 ± 0.8 85 ± 17 -3.8
3.1.01.03. Viral core-E1 signal peptide 2lif Hepatitis C virus Viral 1 1 29.6 ± 5.0 19 ± 10 -16.6
3.1.11.01. Pancreatic hormone 1v1d Bos taurus Secreted 1 0 1.2 ± 3.0 79 ± 32 -1.9
1.1.09.01. Copper efflux ATPase 3rfu Legionella pneumophila Bact. Gram-neg inner 1 8 30.0 ± 0.4 16 ± 1 -72.1
1.1.01.02. Orexin receptor type 1 4zjc Homo sapiens Eukaryo. plasma 1 7 31.6 ± 1.5 4 ± 1 -67.5
2.3.06.07. Tentative lipase 2zyr Archaeoglobus fulgidus Secreted 1 0 3.0 ± 1.0 57 ± 8 -7.5
1.3.07.01. Plasminogen activator PLA (coagulase/fibrinolysin) 2x55 Yersinia pestis Bact. Gram-neg outer 1 10 25.6 ± 1.9 4 ± 5 -43.9
1.1.09.01. Calcium ATPase, E1 state, with macrolide BLS 4ycm Oryctolagus cuniculus Endoplasm. reticulum 1 10 3.2 ± 1.8 21 ± 1 -66.3
2.3.08.01. Patatin 1oxw Solanum cardiophyllum Secreted 1 0 3.9 ± 2.0 28 ± 11 -6.5
2.3.06.18. Tle1 effector of type VI lipase 4o5p Pseudomonas aeruginosa Secreted 1 0 3.1 ± 2.5 85 ± 8 -5.8
1.1.69.01. HIG1 domain family member 1B 2lon Homo sapiens Mitochon. inner 1 2 22.4 ± 1.2 19 ± 0 -13.7
1.2.43.01. Envelope glycoprotein, West Nile virus, structure 2 2i69 West Nile virus Viral 1 0 6.7 ± 2.8 5 ± 12 -5.0
2.2.11.01. Synaptotagmin-1, C2B domain (Calcium bound) 1uov Rattus norvegicus Eukaryo. plasma 1 0 1.7 ± 1.8 36 ± 13 -3.7
2.2.15.01. Gamma-crystallin F 1m8u Bos taurus Secreted 1 0 0.7 ± 1.2 85 ± 4 -4.9
1.1.01.01. Xanthorhodopsin 3ddl Salinibacter ruber Bact. Gram-neg inner 1 7 28.2 ± 1.8 11 ± 0 -60.7
2.1.18.01. Annexin II 1w7b Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.2 87 ± 18 -3.8
2.3.05.06. Endothelin-converting enzyme 2 2pxx Homo sapiens Golgi 1 0 7.1 ± 1.3 37 ± 8 -8.4
2.4.16.01. Alpha-insect toxin LqhaIT 2yeo Leiurus quinquestriatus hebraeus Secreted 1 0 3.5 ± 0.8 43 ± 13 -5.9
2.3.24.02. Phosphoglycolate phosphatase 1l6r Thermoplasma acidophilum Undefined 1 0 3.6 ± 0.5 86 ± 3 -7.5
1.1.100.01. Voltage-sensor domain of phosphatase, conformation 1 4g80 Ciona intestinalis Eukaryo. plasma 1 4 29.4 ± 1.4 14 ± 1 -44.6
3.1.12.01. Endothelin-1 1edn Homo sapiens Secreted 1 0 4.3 ± 1.2 71 ± 25 -5.4
2.2.34.07. Asteropsin D 2lzy Asteropus sp. Secreted 1 0 4.7 ± 1.5 49 ± 29 -3.0
1.1.30.01. Membrane protein insertase YidC, structure 1 3wvf Escherichia coli Bact. Gram-neg inner 1 5 26.8 ± 1.3 10 ± 2 -46.7
2.2.06.02. Fatty acid-binding protein 2 2ftb Ambystoma mexicanum (Axolotl) Eukaryo. plasma 1 0 0.6 ± 2.0 77 ± 20 -1.7
1.2.33.02. Monoamine oxidase A 2z5x Homo sapiens Mitochon. outer 1 1 31.0 ± 2.1 17 ± 1 -21.4
2.1.01.01. Ammodytin L1 isoform 3ux7 Vipera ammodytes meridionalis Secreted 1 0 2.7 ± 0.3 82 ± 1 -13.2
2.2.21.01. Hisactophilin-1 1hce Dictyostelium discoideum Eukaryo. plasma 1 0 3.5 ± 1.1 60 ± 15 -1.6
1.2.41.01. Acyl-CoA-binding domain-containing protein 5 3flv Homo sapiens Peroxisome 1 0 4.6 ± 2.8 28 ± 3 -4.9
2.4.16.04. Floral defensin-like protein 1 1n4n Petunia hybrida Secreted 1 0 1.8 ± 0.8 6 ± 9 -3.8
2.2.09.02. Diisopropyl-fluorophosphatase 3o4p Loligo vulgaris (Common European squid) Undefined 1 0 4.6 ± 1.3 82 ± 5 -6.6
1.3.20.01. Outer membrane cobalamin transporter BtuB, with cyanocobalamin 3m8d Escherichia coli Bact. Gram-neg outer 1 22 23.3 ± 0.8 6 ± 1 -70.5
2.2.04.01. 9-cis-epoxycarotenoid dioxygenase 1, chloroplastic 3npe Zea mays Thylakoid 1 0 6.0 ± 0.1 30 ± 5 -11.1
2.1.03.01. Alpha-toxin (PHLC1_CLOPE), closed state (inactive) 1gyg Clostridium perfringens Secreted 1 0 6.1 ± 2.0 75 ± 6 -5.9
2.2.35.01. Pneumolysin, structure 7 4zgh Streptococcus pneumoniae Secreted 1 0 5.0 ± 2.5 24 ± 25 -4.9
1.1.38.01. Na+/drug antiporter NorM, outward-open, structure 2 5c6p Neisseria gonorrhoeae Bact. Gram-neg inner 1 12 28.6 ± 1.1 13 ± 0 -45.3
3.1.02.05. Acetylcholine receptor, subunit alpha, TMH II 1dxz Torpedo californica Eukaryo. plasma 1 1 29.8 ± 3.6 25 ± 4 -23.1
2.3.18.02. Phthiocerol/phthiodiolone dimycocerosyl transferase 1q9j Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 6.7 ± 2.2 25 ± 6 -5.2
2.1.01.03. Phospholipase A2 group XIII 4aup Tuber borchii Secreted 1 0 3.7 ± 0.7 63 ± 6 -7.7
2.3.06.05. Carboxylesterase 3cn9 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 3.5 ± 2.1 11 ± 32 -4.1
2.2.06.02. Myelin P2 protein 1pmp Bos taurus Eukaryo. plasma 1 0 2.7 ± 1.3 61 ± 13 -6.1
2.3.16.07. Ras-related protein Rab-7a 1vg8 Rattus norvegicus Endosome 1 0 1.7 ± 0.5 74 ± 3 -5.3
3.2.03.01. Maurocalcine 1s6w Scorpio maurus Secreted 1 0 1.8 ± 1.6 89 ± 21 -2.3
3.1.04.09. Membrane-permeabilizing peptide (654-676) from hemocyanin 2n1c Litopenaeus vannamei (Whiteleg shrimp) Undefined 1 0 6.5 ± 1.3 90 ± 9 -6.3
1.3.20.01. Transferrin-binding protein A, complex with full-length transferrin 3v8x Neisseria meningitidis Bact. Gram-neg outer 1 22 23.2 ± 0.6 3 ± 0 -66.6
2.2.20.01. Rho guanine nucleotide exchange factor 9, conformation 2 4mt6 Rattus norvegicus Eukaryo. plasma 1 0 3.0 ± 1.9 68 ± 4 -5.1
2.2.41.01. Alpha-defensin 5 1zmp Homo sapiens Secreted 1 0 4.2 ± 1.6 84 ± 14 -2.8
3.1.28.08. Ocellatin-F1 5ua8 Leptodactylus labyrinthicus Secreted 1 0 6.1 ± 0.8 71 ± 7 -10.0
1.1.01.01. Chloride pumping rhodopsin 5b2n Nonlabens marinus Bact. Gram-neg inner 1 7 32.0 ± 1.0 12 ± 0 -63.1
3.1.03.01. Myc box-dependent-interacting protein 1, membrane anchor helix (peptide 1-33) 2rnd Homo sapiens Eukaryo. plasma 1 0 4.0 ± 0.4 85 ± 2 -8.4
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 7 3ar9 Oryctolagus cuniculus Endoplasm. reticulum 1 10 29.0 ± 0.9 20 ± 0 -73.8
2.3.06.01. Bile-salt activated lipase, structure 2 1jmy Homo sapiens Secreted 1 0 5.0 ± 1.4 85 ± 9 -5.3
2.4.51.01. Heme acquisition protein HasA 4jet Yersinia pestis Secreted 1 0 4.8 ± 0.9 29 ± 2 -7.0
2.2.27.01. C1 domain of protein kinase C gamma 1tbn Rattus rattus Eukaryo. plasma 1 0 4.8 ± 1.6 42 ± 19 -3.7
2.2.26.01. FYVE domain of Vps27 protein 1vfy Saccharomyces cerevisiae Vacuole 1 0 3.7 ± 1.8 24 ± 19 -4.2
2.2.34.02. M-theraphotoxin-Gr1a 1lu8 Grammostola rosea (Chilean rose tarantula) Secreted 1 0 2.8 ± 0.9 69 ± 7 -7.2
3.3.03.01. Dodecamer of norleucine 1r9v Designed proteins Undefined 1 0 31.2 ± 6.2 5 ± 16 -16.3
1.3.19.01. Porin OprdG 4ft6 Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.4 ± 1.4 4 ± 0 -62.4
3.1.02.15. Glutamate receptor ionotropic, NMDA 1, TMH 2 2nr1 Homo sapiens Eukaryo. plasma 1 0 7.0 ± 3.7 84 ± 0 -12.5
2.3.06.09. Lysin B from mycobacteriophage 3hc7 Mycobacterium phage D29 Bact. Gram-pos plas. 1 0 6.6 ± 2.0 50 ± 12 -7.0
2.2.41.02. Toxin APETx1 1wqk Anthopleura elegantissima (Sea anemone) Secreted 1 0 4.0 ± 1.4 32 ± 18 -7.3
3.2.09.03. Tyrocidine A analogue AC3.27 6b34 Bacillus brevis Secreted 1 0 7.6 ± 1.6 74 ± 9 -9.1
1.1.15.01. Nicotinic acetylcholine receptor, beta-2, in LDAO micelles 2lm2 Homo sapiens Eukaryo. plasma 1 4 29.2 ± 1.6 14 ± 2 -48.8
2.1.27.01. Cry2Aa 1i5p Bacillus thuringiensis Secreted 1 0 3.4 ± 1.2 16 ± 12 -7.0
3.4.12.01. Actinomycin D 1a7y Streptomyces antibioticus Secreted 1 0 11.5 ± 0.9 89 ± 11 -12.2
1.1.01.03. Ectodomain of G-protein coupled receptor Mth 1fjr Drosophila melanogaster Eukaryo. plasma 1 0 1.8 ± 1.5 56 ± 13 -4.3
2.3.08.02. Cytosolic phospholipase A2, group IVA 1cjy Homo sapiens Vesicle 1 0 5.8 ± 1.0 70 ± 9 -9.9
2.1.29.03. Apolipoprotein C-I, peptide 61-79 1alf Homo sapiens Secreted 1 0 4.1 ± 0.5 86 ± 3 -9.4
3.1.02.01. Third extracellular loop of cholecystokinin A receptor 1hzn Homo sapiens Eukaryo. plasma 1 0 3.4 ± 0.9 81 ± 2 -10.3
1.1.39.02. Biotin transporter BioY 4dve Lactococcus lactis Bact. Gram-pos plas. 1 6 31.8 ± 1.2 13 ± 1 -71.7
2.1.01.01. Phospholipase A2, group IB 3elo Homo sapiens Secreted 1 0 0.4 ± 1.5 52 ± 16 -3.5
3.2.05.02. Benenodin-1, state 2 6b5w Asticcacaulis benevestitus Secreted 1 0 3.3 ± 1.6 82 ± 7 -5.8
1.2.57.01. Reticulon-4 2ko2 Mus musculus Endoplasm. reticulum 1 0 2.5 ± 0.3 83 ± 1 -6.2
2.2.34.01. Omega conotoxin TxVII 1f3k Conus textile Secreted 1 0 2.8 ± 1.4 57 ± 18 -4.5
3.2.06.01. Growth-blocking peptide 2dj9 Mamestra brassicae Secreted 1 0 2.2 ± 0.7 31 ± 4 -6.2
1.1.25.02. Lactose permease LacY, structure 3 1pv6 Escherichia coli Bact. Gram-neg inner 1 12 31.8 ± 1.2 5 ± 0 -89.1
2.3.14.01. SEC14-like protein 2 (supernatant factor protein) 1o6u Homo sapiens Eukaryo. plasma 1 0 3.6 ± 1.4 62 ± 14 -4.9
2.2.34.10. Imperatoxin-A 1ie6 Pandinus imperator (Emperor scorpion) Secreted 1 0 2.6 ± 0.8 55 ± 13 -3.1
1.1.08.01. F0 ATP synthase, subunit c 1a91 Escherichia coli Bact. Gram-neg inner 1 2 28.4 ± 8.0 44 ± 4 -24.2
1.3.20.01. Outer membrane receptor PiuA 5fp1 Acinetobacter baumannii Bact. Gram-neg outer 1 22 23.6 ± 0.9 4 ± 1 -68.9
1.1.25.06. Glucose transporter GLUT5, inward-open 4yb9 Bos taurus Eukaryo. plasma 1 12 31.8 ± 1.0 6 ± 0 -89.9
1.1.86.01. Protein YetJ, closed conformation 4pgr Bacillus subtilis Bact. Gram-pos plas. 1 7 29.8 ± 2.0 15 ± 2 -72.0
2.2.34.11. Tricyclon-A 1yp8 Viola arvensis Secreted 1 0 4.4 ± 1.7 71 ± 19 -4.7
2.2.12.01. Ganglioside GM2 activator, different conformation 1pub Homo sapiens Lysosome 1 0 4.9 ± 0.7 50 ± 8 -7.3
1.1.116.01. Glycerol-3-phosphate acyltransferase, structure 3 5xj7 Aquifex aeolicus Bact. Gram-neg inner 1 7 26.2 ± 1.4 6 ± 3 -56.7
1.2.32.01. Lanosterol 14-alpha demethylase (CYP51), with lanosterol 5eqb Saccharomyces cerevisiae Endoplasm. reticulum 1 1 29.8 ± 0.9 39 ± 2 -34.5
2.2.35.01. Suilysin 3hvn Streptococcus suis Secreted 1 0 5.6 ± 1.1 5 ± 4 -6.4
1.1.25.03. Transporter YajR 3wdo Escherichia coli Bact. Gram-neg inner 1 12 31.0 ± 1.4 2 ± 0 -81.8
1.2.54.01. Dihydroorotate dehydrogenase 3i65 Plasmodium falciparum Mitochon. inner 1 0 5.1 ± 1.0 47 ± 6 -13.6
1.2.45.01. Envelope small membrane protein 2mm4 Human SARS coronavirus Viral 1 1 29.6 ± 4.1 53 ± 1 -32.2
3.1.11.02. Glucagon analog 1bh0 Homo sapiens Secreted 1 0 4.9 ± 4.2 78 ± 2 -6.1
1.1.08.01. ATP synthase subunit b, peptide 1-33 1b9u Escherichia coli Bact. Gram-neg inner 1 1 29.8 ± 4.0 41 ± 2 -23.1
2.1.02.01. Arachidonate 15-lipoxygenase 3rde Sus scrofa Eukaryo. plasma 1 0 6.9 ± 0.4 83 ± 1 -8.7
1.1.25.05. Di-or tripeptide:H+ symporter, inward open, structure 3 5d6k Streptococcus thermophilus Bact. Gram-pos plas. 1 14 32.8 ± 1.0 5 ± 0 -112.6
3.1.13.01. Islet amyloid polypeptide, fragment 34-70 2kb8 Homo sapiens Secreted 1 0 3.9 ± 4.2 90 ± 1 -10.2
2.3.13.06. Chloride intracellular channel protein 1 1rk4 Homo sapiens Nuclear outer 1 0 3.0 ± 1.0 40 ± 5 -5.5
1.1.01.03. Glucagon receptor, structure 1 4l6r Homo sapiens Eukaryo. plasma 1 7 28.8 ± 1.8 20 ± 0 -46.7
2.3.06.06. Lipase 1, open (active) state 1lpp Candida rugosa Secreted 1 0 10.0 ± 0.4 83 ± 1 -28.0
3.1.35.01. Cn-AMP1 peptide 2n0v Cocos nucifera Secreted 1 0 2.9 ± 1.3 73 ± 18 -2.3
2.3.06.11. Monoglyceride lipase MGLL, closed conformation 3pe6 Homo sapiens Eukaryo. plasma 1 0 0.9 ± 3.0 54 ± 28 -2.7
2.2.14.01. Coagulation factor VIII, light chain 3j2s Homo sapiens Eukaryo. plasma 1 0 4.8 ± 1.0 34 ± 15 -6.1
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), structure 2 5fsa Candida albicans Endoplasm. reticulum 1 0 9.0 ± 0.8 61 ± 2 -18.0
2.3.06.08. Pancreatic lipase 1bu8 Rattus norvegicus Secreted 1 0 3.5 ± 1.3 87 ± 10 -6.1
3.1.28.04. Esculentin-1A, structure 1 2n6m Pelophylax esculentus Secreted 1 0 7.9 ± 0.4 67 ± 5 -7.9
2.3.09.01. Cytidylyltransferase, second membrane-anchoring helix 1pei Rattus norvegicus Eukaryo. plasma 1 0 4.9 ± 1.0 83 ± 11 -8.2
1.2.45.02. Small hydrophobic protein, peptide 39-49 2nb8 Human respiratory syncytial virus Viral 1 0 8.5 ± 1.2 57 ± 13 -5.9
2.2.34.02. Neurotoxin Hm-3 2mqu Heriaeus melloteei Secreted 1 0 2.4 ± 0.6 75 ± 11 -7.4
2.3.14.02. Uncharacterized protein 2q3l Shewanella loihica Bact. Gram-neg inner 1 0 6.0 ± 0.5 64 ± 4 -12.6
1.1.01.02. Cannabinoid receptor 1, structure 2 5u09 Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 9 ± 0 -71.8
2.4.06.01. START and PH domains of collagen type IV alpha-3-binding protein 5jjd Homo sapiens Golgi 1 0 1.4 ± 2.6 48 ± 16 -4.4
2.1.42.01. Putative carnobacteriocin-B2 immunity protein 1tdp Carnobacterium maltaromaticum Secreted 1 0 4.4 ± 0.5 90 ± 9 -4.3
2.4.28.01. Phenazine biosynthesis protein PhzF 1s7j Enterococcus faecalis Undefined 1 0 1.8 ± 0.7 77 ± 2 -4.3
1.3.14.01. Toluene transporter TodX 3bs0 Pseudomonas putida Bact. Gram-neg outer 1 14 23.4 ± 1.4 7 ± 7 -61.3
2.1.10.01. Accelerated-cell-death 11 apo-protein 4nt1 Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 2.0 85 ± 7 -5.4
1.1.02.06. Light-harvesting complex CP29 3pl9 Spinacia oleracea Thylakoid 1 3 29.8 ± 1.6 2 ± 2 -66.6
3.1.26.01. Pleurocidin 1z64 Pseudopleuronectes americanus Secreted 1 0 5.4 ± 1.3 87 ± 18 -12.8
3.1.18.02. Phenol-soluble modulin beta-2 5kgz Staphylococcus aureus Secreted 1 0 6.2 ± 2.5 55 ± 7 -6.2
2.2.20.01. RAC-gamma serine/threonine-protein kinase 2x18 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.1 53 ± 4 -3.8
1.2.22.01. Bcl-2-like protein 1, complex with alpha-beta-foldamer 4a1u Homo sapiens Mitochon. outer 1 0 5.8 ± 0.3 26 ± 5 -5.7
2.1.60.01. Potassium channel toxin ShK 1roo Stoichactis helianthus Secreted 1 0 1.2 ± 1.2 46 ± 8 -3.7
2.2.20.01. Rac-alpha serine/threonine kinase 1unq Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.0 67 ± 18 -3.9
1.1.10.08. Multidrug resistance protein 1 (MRP1), structure 2 5uja Bos taurus Eukaryo. plasma 1 17 31.4 ± 0.8 16 ± 0 -103.8
2.4.06.01. Lipid transport protein Mln64 (StARD3) 1em2 Homo sapiens Endosome 1 0 2.0 ± 1.1 82 ± 12 -5.0
2.4.16.06. Mytilin-B 2eem Mytilus edulis (Blue mussel) Secreted 1 0 3.6 ± 1.4 76 ± 8 -3.2
3.1.05.03. LAK160-P12 2l9a Designed proteins Undefined 1 0 4.9 ± 3.1 87 ± 1 -6.7
1.1.01.02. P2Y purinoceptor 12, structure 2 4pxz Homo sapiens Eukaryo. plasma 1 7 36.0 ± 1.9 4 ± 3 -79.5
3.1.21.01. Cecropin-P1 2n92 Ascaris suum Secreted 1 0 1.6 ± 3.4 90 ± 0 -4.1
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 3ml9 Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.8 83 ± 2 -6.0
2.2.41.03. Big defensin, segment 43-72 2rq2 Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 1 25.6 ± 4.4 18 ± 2 -13.5
2.2.39.01. Muscarinic m1-toxin1, chimeric sequence 3fev Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 5.5 ± 1.5 76 ± 8 -6.3
1.1.25.02. Lactose permease LacY, structure 2 2v8n Escherichia coli Bact. Gram-neg inner 1 12 31.8 ± 0.8 5 ± 0 -86.4
2.3.06.01. Butyryl cholinesterase 1p0i Homo sapiens Eukaryo. plasma 1 0 3.1 ± 0.8 43 ± 10 -6.4
1.1.01.03. Glucagon-like peptide 1 receptor with Gs-protein 5vai Oryctolagus cuniculus Eukaryo. plasma 1 7 30.6 ± 1.6 12 ± 4 -48.2
3.1.15.04. Bacteriocin plantaricin K (PlnK) 2keg Lactobacillus plantarum Secreted 1 0 3.3 ± 1.1 83 ± 11 -8.4
3.2.05.02. Sphingopyxin I 5jqf Sphingopyxis alaskensis Undefined 1 0 1.7 ± 1.8 40 ± 16 -3.7
1.3.19.02. Alginate export protein, AlgE, conformation 2 4afk Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 24.8 ± 0.9 3 ± 0 -73.0
2.4.07.01. PX domain of sorting nexin-14 4bgj Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 72 ± 22 -4.3
2.2.16.01. Lipoprotein lppX 2byo Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 1.9 ± 1.7 80 ± 13 -4.8
2.3.06.08. Pancreatic lipase-related protein 2 1w52 Equus caballus Secreted 1 0 4.8 ± 0.2 83 ± 0 -12.7
2.3.25.02. Lipase 5mal Streptomyces rimosus Secreted 1 0 3.9 ± 0.8 64 ± 20 -6.3
1.2.42.01. UDP-2,3-diacylglucosamine hydrolase 5b49 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 9.9 ± 1.9 42 ± 16 -4.9
2.4.07.01. NADPH oxidase organizer 1, PX domain 2l73 Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.9 72 ± 13 -5.1
1.2.32.01. Cytochrome P450 2A13 2p85 Homo sapiens Endoplasm. reticulum 1 0 4.9 ± 0.4 47 ± 2 -10.0
2.1.01.01. Snake phospholipase A2, group II, RVV-VD 1vip Vipera russelli Secreted 1 0 4.4 ± 0.8 85 ± 11 -9.5
3.1.20.01. Conotoxin pc16a 2ler Conus pictus Secreted 1 0 4.0 ± 1.0 64 ± 7 -4.1
2.1.50.01. Phosphate transport system protein phoU homolog 2 1sum Thermotoga maritima Bact. Gram-neg inner 1 0 4.9 ± 2.1 68 ± 4 -4.3
1.1.38.01. Multidrug and toxic compound extrusion transporter 5xjj Camelina sativa Eukaryo. plasma 1 12 31.0 ± 0.6 4 ± 0 -91.4
2.2.03.01. Saccharopepsin 1fq5 Saccharomyces cerevisiae Vacuole 1 0 3.8 ± 0.8 84 ± 6 -8.1
2.2.33.01. Hevein 1q9b Hevea brasiliensis (Para rubber tree) Secreted 1 0 1.0 ± 1.0 90 ± 11 -1.8
1.3.24.01. Cation efflux system protein CusC, monomer 4k7k Escherichia coli Bact. Gram-neg outer 1 0 3.2 ± 0.9 85 ± 1 -7.2
1.2.03.05. Erythropoietin receptor (236-284) 2mv6 Homo sapiens Eukaryo. plasma 1 1 31.4 ± 3.3 34 ± 6 -36.3
2.1.30.01. Membrane-integrating protein mistic, mstX 1ygm Bacillus subtilis Bact. Gram-pos plas. 1 0 2.6 ± 1.8 31 ± 6 -5.2
2.1.01.01. Phospholipase A2 homolog, ammodytin L 3dih Vipera ammodytes ammodytes Secreted 1 0 5.0 ± 0.4 82 ± 5 -14.4
2.3.25.01. Acyloxyacyl hydrolase, structure 2 5w7d Mus musculus Secreted 1 0 1.6 ± 0.8 82 ± 12 -3.6
1.2.01.01. Receptor tyrosine-protein kinase erbB-2 1n8y Rattus norvegicus Eukaryo. plasma 1 0 3.4 ± 3.0 53 ± 5 -4.2
2.1.04.01. Alpha-dioxygenase 1 4hhr Arabidopsis thaliana Endoplasm. reticulum 1 0 10.8 ± 0.1 68 ± 2 -31.4
1.2.11.02. Capsid protein G8P, monomer 2xkm Bacteriophage Pf1 Secreted 1 1 29.2 ± 4.6 34 ± 1 -23.0
3.2.05.02. Lassomycin 2mai Lentzea kentuckyensis Secreted 1 0 3.1 ± 1.0 72 ± 9 -4.7
1.1.01.02. Melanocortin-4 receptor model (active state) with agonist NDP-MSH 2iqr Homo sapiens Eukaryo. plasma 1 7 33.5 ± 2.0 24 ± 0 -60.6
1.2.17.02. Synaptobrevin homolog YKT6 3kyq Rattus norvegicus Vesicle 1 0 2.5 ± 2.0 53 ± 8 -4.9
2.2.34.01. Omega-conotoxin SVIB 1mvj Conus striatus Secreted 1 0 1.1 ± 2.1 20 ± 24 -2.1
1.3.30.01. Phenol degradation pathway involved protein 4rl8 Pseudomonas putida Bact. Gram-neg outer 1 12 23.4 ± 1.1 6 ± 1 -47.9
3.1.04.08. Truncated superoxide dismutase 1 2mp3 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 83 ± 0 -6.3
2.1.01.01. Snake phospholipase A2 natratoxin, group I 2osh Naja atra Secreted 1 0 2.6 ± 1.6 83 ± 11 -6.1
2.4.16.02. Navitoxin 2rty Nasonia vitripennis (Parasitic wasp) Secreted 1 0 1.2 ± 3.4 90 ± 17 -3.9
2.2.34.03. Toxin Ado1 1lmr Agriosphodrus dohrni Secreted 1 0 3.1 ± 1.6 60 ± 19 -4.7
2.2.35.01. Intermedilysin - CD59 receptor complex, disulfide-locked mutant 4bik Streptococcus intermedius Secreted 1 0 5.9 ± 3.1 28 ± 43 -6.4
1.1.60.01. Protease GlpG, conformation 2 2nrf Escherichia coli Bact. Gram-neg inner 1 6 27.6 ± 1.5 13 ± 2 -45.9
1.2.25.02. Na,K-ATPase regulatory protein FXYD4 2jp3 Rattus norvegicus Eukaryo. plasma 1 1 31.8 ± 3.2 18 ± 7 -20.2
3.1.07.03. Hemagglutinin, peptide 330-349, F9A 2jrd Influenza virus Viral 1 0 8.1 ± 4.0 71 ± 5 -6.8
3.1.20.01. Alpha-conotoxin PIA 1zlc Conus purpurascens (Purple cone) Secreted 1 0 2.6 ± 1.3 59 ± 16 -4.3
2.1.08.01. Mono-heme c-type cytochrome ScyA 1kx7 Shewanella putrefaciens Bact. Gram-neg inner 1 0 1.8 ± 1.1 72 ± 12 -3.2
1.3.17.02. BamABCDE complex, structure 2 5ljo Escherichia coli Bact. Gram-neg outer 1 16 23.2 ± 0.4 13 ± 0 -55.7
2.3.02.04. Phosphatidylinositol-specific phospholipase C1 3h4x Streptomyces antibioticus Bact. Gram-pos plas. 1 0 3.7 ± 0.4 63 ± 2 -7.3
3.1.29.03. Prophenin-1 2i1d Sus scrofa Secreted 1 0 4.8 ± 1.9 70 ± 35 -5.9
1.2.48.01. Lysosome-associated membrane glycoprotein 2, monomer 2mof Homo sapiens Lysosome 1 1 30.6 ± 3.5 42 ± 5 -28.0
2.3.13.04. Glutathione peroxidase 8 3kij Homo sapiens Endoplasm. reticulum 1 0 3.4 ± 2.7 56 ± 16 -6.1
2.2.41.01. Spheniscin-2 (bird defensin) 1ut3 Aptenodytes patagonicus Secreted 1 0 3.6 ± 1.6 44 ± 17 -6.2
2.2.35.01. Pneumolysin, structure 1 4qqq Streptococcus pneumoniae Secreted 1 0 4.6 ± 3.7 27 ± 7 -6.8
2.1.18.01. Annexin D1 1ycn Arabidopsis thaliana Eukaryo. plasma 1 0 2.3 ± 1.1 78 ± 14 -3.4
2.3.21.01. Protein-tyrosine phosphatase, mitochondrial 1 3rgq Mus musculus Mitochon. inner 1 0 1.7 ± 0.7 54 ± 7 -4.9
1.2.23.01. M2 proton channel of Influenza A, monomer 4rwb Influenza virus Viral 1 1 31.6 ± 4.5 46 ± 6 -25.4
2.2.39.01. Muscarinic m1-toxin1 2vlw Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 3.4 ± 0.9 82 ± 9 -4.9
2.1.08.01. Cytochrome c2 1cxa Rhodobacter sphaeroides Bact. Gram-neg inner 1 0 2.0 ± 1.2 88 ± 13 -4.3
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 1 1zhx Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.9 90 ± 7 -5.0
3.1.05.03. Human platelet factor 4 based peptide, 56-70, modified 1djf Designed proteins Undefined 1 0 1.9 ± 1.4 87 ± 8 -4.9
1.3.21.01. P pilus usher PapC translocation domain 2vqi Escherichia coli Bact. Gram-neg outer 1 24 23.1 ± 1.0 3 ± 0 -61.0
1.2.50.02. Nakanori protein 5h0q Grifola frondosa Eukaryo. plasma 1 0 0.9 ± 1.8 37 ± 15 -3.1
2.3.16.06. ADP-ribosylation factor 1 (ARF1), different conformation 2ksq Saccharomyces cerevisiae Golgi 1 0 4.7 ± 0.1 62 ± 0 -10.4
3.1.28.03. Bombinin-H5 2ap8 Bombina variegata (Yellow-bellied toad) Secreted 1 0 8.6 ± 4.2 77 ± 3 -10.6
3.1.29.01. LL-37-derived peptide 2l5m Designed proteins Undefined 1 0 6.1 ± 1.0 89 ± 7 -9.7
1.3.21.01. Outer membrane usher protein FimD, complex with FimC-FimF-FimG-FimH 4j3o Escherichia coli Bact. Gram-neg outer 1 24 23.8 ± 1.4 1 ± 1 -52.9
1.1.15.01. Neuronal acetylcholine receptor, alpha-7 2maw Homo sapiens Eukaryo. plasma 1 4 30.0 ± 1.4 14 ± 1 -41.4
1.2.32.01. Cytochrome P450 2C9, structure 4 5x23 Homo sapiens Endoplasm. reticulum 1 0 6.9 ± 0.8 53 ± 8 -12.1
3.1.14.01. Eledoisin 1mxq Eledone cirrhosa (Curled octopus) Secreted 1 0 2.9 ± 1.7 59 ± 19 -5.0
2.4.05.01. Uncharacterized protein 3bkr Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.4 ± 6.2 50 ± 73 -1.2
3.1.03.08. Lipid interacting helix (227-245) of digalactosyldiacylglycerol synthase 2l7c Arabidopsis thaliana Chloroplast outer 1 0 3.3 ± 3.6 88 ± 1 -6.0
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 1 3mok Pseudomonas aeruginosa Secreted 1 0 4.5 ± 0.7 37 ± 7 -6.7
2.3.10.03. LPS heptosyltransferase II, WaaF 1psw Escherichia coli Bact. Gram-neg inner 1 0 3.1 ± 1.1 58 ± 8 -5.6
2.2.11.01. Synaptotagmin-3 3hn8 Rattus norvegicus Eukaryo. plasma 1 0 4.0 ± 3.1 74 ± 19 -4.0
1.1.01.02. Neurotensin receptor type 1, structure 4 5t04 Rattus norvegicus Eukaryo. plasma 1 7 31.4 ± 0.8 7 ± 1 -69.8
3.1.04.10. TAR DNA-binding protein 43, peptide 307-349 2n2c Homo sapiens Nuclear inner 1 0 7.7 ± 0.7 89 ± 6 -13.4
2.2.41.01. Oral alpha defensin 1 2k1i Macaca mulatta Secreted 1 0 0.9 ± 3.2 70 ± 15 -2.2
2.3.22.02. NrdI protein 2x2o Bacillus cereus Undefined 1 0 3.6 ± 0.5 77 ± 4 -4.6
1.3.10.01. Acidic sugar-specific porin NanC 2wjr Escherichia coli Bact. Gram-neg outer 1 12 23.3 ± 1.5 4 ± 4 -47.5
2.2.27.01. C1 domain of protein kinase C gamma 2e73 Homo sapiens Eukaryo. plasma 1 0 3.5 ± 1.3 53 ± 9 -4.7
2.2.05.01. Plantacyanin 1f56 Spinacia oleracea Thylakoid 1 0 1.4 ± 1.5 11 ± 15 -2.0