PDB ID or protein name

All proteins in OPM (3890 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.1.25.03. Enterocin 7A 2m5z Enterococcus faecalis Secreted 0 0 4.4 ± 0.3 57 ± 3 -5.3
2.1.63.01. Phosphatidylinositol mannoside acyltransferase PatA 5f34 Mycobacterium smegmatis Bact. Gram-pos plas. 0 0 3.9 ± 0.5 58 ± 1 -6.9
2.2.34.02. Mu-theraphotoxin-Hhn1b 1niy Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.2 ± 0.7 71 ± 6 -4.6
2.2.34.11. Kalata-B7 2jwm Oldenlandia affinis Secreted 1 0 2.7 ± 2.2 86 ± 28 -4.8
3.2.05.02. Sphaericin 5gvo Planomonospora sphaerica Secreted 1 0 7.9 ± 3.6 31 ± 13 -11.0
1.3.20.01. Pyoverdine Outer Membrane Receptor FpvA 2iah Pseudomonas aeruginosa Bact. Gram-neg outer 1 22 24.0 ± 0.5 8 ± 0 -79.7
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 8 4c0c Trypanosoma cruzi Endoplasm. reticulum 1 0 9.4 ± 1.9 64 ± 7 -10.9
2.4.16.03. Charybdotoxin 2crd Leiurus quinquestriatus hebraeus Secreted 1 0 1.1 ± 1.5 86 ± 15 -3.2
3.4.08.04. Met-enkephalin 1plw Homo sapiens Secreted 1 0 4.9 ± 0.8 85 ± 17 -3.8
1.1.91.01. Delta(14)-sterol reductase 4quv Methylomicrobium alcaliphilum Bact. Gram-neg inner 1 10 28.2 ± 1.4 11 ± 3 -81.4
2.1.02.01. Arachidonate 5-lipoxygenase 3o8y Homo sapiens Eukaryo. plasma 1 0 2.1 ± 1.0 89 ± 4 -3.8
2.3.05.01. Flavoprotein-ubiquinone oxydoreductase 2gmh Sus scrofa Mitochon. inner 1 0 7.2 ± 0.8 38 ± 4 -18.5
3.1.11.01. Pancreatic hormone 1v1d Bos taurus Secreted 1 0 1.2 ± 3.0 79 ± 32 -1.9
2.1.18.01. Annexin III 1axn Homo sapiens Eukaryo. plasma 1 0 2.7 ± 0.8 77 ± 11 -5.7
2.3.06.07. Tentative lipase 2zyr Archaeoglobus fulgidus Secreted 1 0 3.0 ± 1.0 57 ± 8 -7.5
2.1.24.01. Saposin A (peptide 60-140), conformation in disc 4ddj Homo sapiens Lysosome 1 0 6.4 ± 0.9 89 ± 3 -8.5
1.3.19.01. Outer membrane porin OprD 2odj Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.0 ± 0.8 8 ± 0 -63.1
1.1.100.01. Voltage-sensor domain of phosphatase, conformation 2 4g7v Ciona intestinalis Eukaryo. plasma 1 4 30.2 ± 1.8 5 ± 0 -49.2
2.3.08.01. Patatin 1oxw Solanum cardiophyllum Secreted 1 0 3.9 ± 2.0 28 ± 11 -6.5
2.3.06.18. Tle1 effector of type VI lipase 4o5p Pseudomonas aeruginosa Secreted 1 0 3.1 ± 2.5 85 ± 8 -5.8
2.2.11.01. Rabphilin-3A 2k3h Mus musculus Eukaryo. plasma 1 0 1.7 ± 2.1 78 ± 16 -4.1
1.1.25.05. Glutathione uptake transporter, structure 1 2xut Shewanella oneidensis Bact. Gram-neg inner 1 14 30.9 ± 1.4 10 ± 0 -102.5
3.1.28.02. Alyteserin-1C 2l5r Alytes obstetricans Secreted 1 0 8.7 ± 4.1 81 ± 0 -14.1
1.1.38.01. H+-driven MATE exporter, outward-open, "bent" conformation 3vvo Pyrococcus furiosus Archaebac. 1 12 31.4 ± 1.1 11 ± 0 -93.1
1.3.21.01. Outer membrane usher protein FimD 3ohn Escherichia coli Bact. Gram-neg outer 1 24 21.2 ± 1.1 5 ± 0 -45.4
1.1.53.01. RAS methyltransferase ICMT 5v7p Tribolium castaneum Endoplasm. reticulum 1 8 29.8 ± 1.2 14 ± 0 -72.4
3.1.14.01. Kassinin 1myu Kassina senegalensis Secreted 1 0 3.4 ± 1.5 59 ± 16 -4.5
2.3.06.06. Mono- and diacylglycerol lipase 5ch8 Penicillium cyclopium Secreted 1 0 2.7 ± 0.3 9 ± 7 -4.2
3.1.02.01. Beta-1 adrenergic receptor, peptide 345-359 1dep Meleagris gallopavo Eukaryo. plasma 1 0 4.4 ± 1.2 76 ± 16 -8.3
2.2.51.01. 25 kDa protein elicitor 3gnz Pythium aphanidermatum Secreted 1 0 5.7 ± 2.5 77 ± 13 -5.1
3.1.02.03. Juxtamembrane helix of ATP synthase subunit b 2khk Escherichia coli Bact. Gram-neg inner 1 0 1.9 ± 0.1 85 ± 3 -3.9
2.2.06.02. Fatty acid-binding protein Sm14 1vyf Schistosoma mansoni Eukaryo. plasma 1 0 5.1 ± 1.2 42 ± 18 -5.2
2.4.05.01. Sterol carrier protein 2 like domain of multifunctional enzyme type 2 1ikt Homo sapiens Peroxisome 1 0 3.5 ± 1.2 75 ± 17 -4.0
2.4.16.02. Defensin heliomicin 1i2u Heliothis virescens (Tobacco budworm moth) Secreted 1 0 3.4 ± 0.4 59 ± 1 -7.6
2.3.28.01. Aldo-keto reductase family 1 member C21 3fjn Mus musculus Undefined 1 0 2.8 ± 1.0 56 ± 3 -5.2
1.1.64.01. Sodium/calcium exchanger, structure 2 3v5s Methanococcus jannaschii Archaebac. 1 10 29.6 ± 1.6 1 ± 2 -75.1
3.2.09.02. Gramicidin S 1tk2 Bacillus brevis Secreted 1 0 8.5 ± 1.7 86 ± 21 -8.6
2.4.51.01. Heme acquisition protein HasA, dimer 4y4s Yersinia pseudotuberculosis Secreted 1 0 1.8 ± 1.1 83 ± 9 -4.2
3.1.04.01. Protein STE5, peptide 44-67 2kgn Saccharomyces cerevisiae Eukaryo. plasma 1 0 6.4 ± 0.9 84 ± 7 -9.8
1.2.32.01. Cytochrome P450 2B4, open state 2 1po5 Oryctolagus cuniculus Endoplasm. reticulum 1 0 3.5 ± 1.4 79 ± 9 -7.2
1.3.22.01. VDAC-1 channel, structure 3 (NMR) 5jdp Homo sapiens Mitochon. outer 1 19 22.4 ± 1.0 8 ± 1 -43.5
2.3.06.07. Lipase 46 kDa form 2hih Staphylococcus hyicus Secreted 1 0 4.6 ± 0.3 83 ± 1 -16.0
2.2.27.01. Diacylglycerol kinase delta 1r79 Homo sapiens Eukaryo. plasma 1 0 3.3 ± 1.6 34 ± 19 -4.9
1.1.01.02. Rhodopsin, complex with arrestin, structure 2 5w0p Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.0 8 ± 0 -83.4
3.1.07.01. Fusion peptide (510-532) of protein gp41 2pjv Human immunodeficiency virus type 1 Endosome 1 0 8.7 ± 3.8 64 ± 4 -10.9
2.4.16.07. Diapause-specific peptide 2e2f Gastrophysa atrocyanea (Leaf beetle) Secreted 1 0 1.3 ± 1.0 30 ± 10 -4.2
2.4.11.01. Crambin, enantiomer 3ue7 Designed proteins Undefined 1 0 3.4 ± 1.7 89 ± 13 -4.6
1.3.17.02. Translocation and assembly module TamA 4c00 Escherichia coli Bact. Gram-neg outer 1 16 23.4 ± 1.3 7 ± 1 -52.2
3.1.02.02. Sodium channel protein type 3 subunit alpha, TMH 2 1qg9 Rattus norvegicus Eukaryo. plasma 1 0 6.8 ± 0.4 86 ± 3 -9.0
2.2.39.01. alpha-Cobratoxin 1ctx Naja kaouthia Secreted 1 0 2.8 ± 1.7 29 ± 18 -4.6
3.1.28.08. Ocellatin-K1 5u9x Leptodactylus knudseni Secreted 1 0 7.4 ± 0.2 77 ± 4 -11.8
3.1.07.02. Cytoplasmic tail (750-854) of protein gp41 5vwl Human immunodeficiency virus type 1 Endosome 1 1 20.8 ± 0.2 24 ± 0 -14.4
2.1.43.01. Acanthaporin 2lrd Acanthamoeba culbertsoni Secreted 1 0 4.8 ± 3.0 56 ± 26 -4.9
3.2.10.01. PawS derived peptide 9 2nb5 Designed proteins Undefined 1 0 5.6 ± 1.3 79 ± 14 -6.5
1.3.19.02. Alginate export protein, AlgE, conformation 5 4xnl Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 25.2 ± 1.1 3 ± 0 -73.6
1.2.04.01. Integrin alpha-X, cytoplasmic helix (peptide 1129-1163) 2luv Homo sapiens Eukaryo. plasma 1 0 4.0 ± 0.5 80 ± 7 -5.8
1.1.39.01. Riboflavin transporter RibU 3p5n Staphylococcus aureus Bact. Gram-pos plas. 1 6 30.6 ± 1.4 6 ± 4 -53.5
2.3.06.07. Lipase I.3, closed state 2z8x Pseudomonas sp. Secreted 1 0 6.8 ± 1.7 74 ± 6 -8.2
2.2.34.02. Mu-theraphotoxin-Pn3a 5t4r Theraphosidae Secreted 1 0 2.9 ± 0.8 87 ± 5 -4.5
1.2.03.04. Leukocyte immunoglobulin-like receptor subfamily B member 4 3p2t Homo sapiens Eukaryo. plasma 1 0 1.7 ± 0.4 84 ± 5 -5.9
2.3.16.08. Interferon-inducible GTPase 1 1tpz Mus musculus Endoplasm. reticulum 1 0 2.5 ± 2.0 37 ± 7 -5.0
2.1.01.01. Snake phospholipase A2, group I 1ozy Micropechis ikaheka Secreted 1 0 2.6 ± 1.0 85 ± 5 -9.0
3.2.04.02. Bowman-Birk type proteinase inhibitor peptide 1gm2 Macrotyloma axillare Secreted 1 0 2.0 ± 1.9 59 ± 14 -3.5
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1kcm Mus musculus Eukaryo. plasma 1 0 5.3 ± 1.4 59 ± 5 -11.0
2.1.20.01. Prothrombin, structure 1 4o03 Homo sapiens Eukaryo. plasma 1 0 8.2 ± 8.2 84 ± 4 -8.8
3.1.11.02. Vasoactive intestinal peptide 2rrh Homo sapiens Secreted 1 0 4.1 ± 0.3 79 ± 9 -5.7
2.2.10.01. High potential iron protein 1hpi Ectothiorhodospira vacuolata Bact. Gram-neg inner 1 0 2.7 ± 1.0 89 ± 12 -4.4
1.3.20.01. Hemophore receptor HasR, structure 2 5c58 Serratia marcescens Bact. Gram-neg outer 1 22 24.8 ± 1.2 2 ± 0 -68.0
1.1.25.06. Glucose transporter GLUT5, outward-open 4ybq Rattus norvegicus Eukaryo. plasma 1 12 32.4 ± 3.0 5 ± 0 -110.6
3.1.11.02. Extendin-4, variant 5niq Heloderma suspectum Secreted 1 0 1.8 ± 0.8 82 ± 18 -4.4
1.1.01.02. Adenosine receptor A2a, inactive state, with annular lipids 4eiy Homo sapiens Eukaryo. plasma 1 7 32.2 ± 1.2 18 ± 0 -70.4
1.2.32.01. Cytochrome P450 2B4, closed state 3 3g5n Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.7 ± 1.8 65 ± 3 -12.1
3.1.28.07. Hylin-A1 2n0o Hypsiboas albopunctatus Secreted 1 0 11.4 ± 0.8 62 ± 4 -15.4
2.1.60.03. Pseudechetoxin 2dda Pseudechis australis Secreted 1 0 4.5 ± 2.8 89 ± 7 -4.3
2.1.02.01. Linoleate 9/13-lipoxygenase, with N-terminal helix 4g33 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 4.3 ± 0.0 16 ± 0 -9.1
1.3.01.01. Outer membrane protein A (OMPA), disordered loops 1qjp Escherichia coli Bact. Gram-neg outer 1 8 25.4 ± 1.5 11 ± 1 -29.5
1.1.01.02. Thrombin (proteinase-activated) receptor 1, PAR1 3vw7 Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.9 1 ± 0 -72.2
2.1.04.01. Fatty acid alpha-oxidase 4kvl Oryza sativa (Rice) Endoplasm. reticulum 1 0 5.5 ± 0.7 90 ± 1 -19.0
2.2.34.01. Omega conotoxin TxVII 1f3k Conus textile Secreted 1 0 2.8 ± 1.4 57 ± 18 -4.5
3.2.06.01. Growth-blocking peptide 2dj9 Mamestra brassicae Secreted 1 0 2.2 ± 0.7 31 ± 4 -6.2
2.1.18.01. Annexin IV 2zhj Rattus norvegicus Eukaryo. plasma 1 0 4.1 ± 1.0 80 ± 1 -7.6
3.1.07.03. Hemagglutinin, fusion peptide 346-365, wild type 1ibn Influenza virus Viral 1 0 9.1 ± 1.2 67 ± 7 -8.0
2.2.34.10. Imperatoxin-A 1ie6 Pandinus imperator (Emperor scorpion) Secreted 1 0 2.6 ± 0.8 55 ± 13 -3.1
1.1.01.02. Rhodopsin, inactive, complex with inverse agonist, 11-cis retinal 1gzm Bos taurus Eukaryo. plasma 1 7 32.2 ± 1.5 11 ± 1 -75.6
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 1 2gek Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 3.4 ± 2.6 85 ± 5 -5.7
2.2.34.11. Tricyclon-A 1yp8 Viola arvensis Secreted 1 0 4.4 ± 1.7 71 ± 19 -4.7
1.1.26.01. Dopamine transporter, outward-facing conformation 4m48 Drosophila melanogaster Eukaryo. plasma 1 12 30.8 ± 1.6 12 ± 0 -101.0
2.2.35.01. Suilysin 3hvn Streptococcus suis Secreted 1 0 5.6 ± 1.1 5 ± 4 -6.4
1.1.25.05. Glutathione uptake transporter, structure 2 4uvm Shewanella oneidensis Bact. Gram-neg inner 1 14 29.8 ± 0.7 10 ± 0 -105.3
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, wild type 2lcy Zaire ebolavirus Viral 1 0 3.5 ± 2.2 59 ± 9 -4.5
3.1.11.02. Glucagon analog 1bh0 Homo sapiens Secreted 1 0 4.9 ± 4.2 78 ± 2 -6.1
1.1.51.01. Vitamin K epoxide reductase, conformation 1 4nv6 Synechococcus sp. Bact. Gram-neg inner 1 5 29.8 ± 1.8 1 ± 1 -54.2
2.1.10.01. Glycolipid transfer protein, structure 1 1tfj Bos taurus Eukaryo. plasma 1 0 3.9 ± 1.0 90 ± 5 -8.3
1.1.01.03. Glucagon receptor, structure 2 5ee7 Homo sapiens Eukaryo. plasma 1 7 31.4 ± 1.4 19 ± 3 -66.2
3.1.13.01. Islet amyloid polypeptide, fragment 34-70 2kb8 Homo sapiens Secreted 1 0 3.9 ± 4.2 90 ± 1 -10.2
1.3.20.01. Hemophore receptor HasR, structure 1 3csl Serratia marcescens Bact. Gram-neg outer 1 22 25.4 ± 1.3 4 ± 5 -72.2
2.1.10.01. Accelerated-cell-death 11 protein, complex with lipid 4nti Arabidopsis thaliana Eukaryo. plasma 1 0 5.7 ± 0.5 80 ± 2 -10.7
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), structure 1 5tz1 Candida albicans Endoplasm. reticulum 1 0 8.7 ± 0.9 67 ± 4 -16.2
2.3.06.06. Lipase 1, open (active) state 1lpp Candida rugosa Secreted 1 0 10.0 ± 0.4 83 ± 1 -28.0
3.1.35.01. Cn-AMP1 peptide 2n0v Cocos nucifera Secreted 1 0 2.9 ± 1.3 73 ± 18 -2.3
1.1.25.09. Iron-regulated transporter, inward-facing state 5ayo Bdellovibrio bacteriovorus Bact. Gram-neg inner 1 12 31.6 ± 0.7 7 ± 1 -89.2
2.2.20.01. Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 3nsu Saccharomyces cerevisiae Eukaryo. plasma 1 0 0.8 ± 1.5 57 ± 12 -4.0
1.2.43.01. Envelope glycoprotein, Zika virus, structure 2 5jhl Zika virus Viral 1 0 5.9 ± 2.8 31 ± 8 -5.5
2.2.15.01. Gamma-crystallin F 1m8u Bos taurus Secreted 1 0 0.7 ± 1.2 85 ± 4 -4.9
1.2.12.01. Fimbrial protein, monomer 1oqw Pseudomonas aeruginosa Bact. Gram-neg inner 1 1 29.8 ± 3.0 31 ± 8 -28.9
2.2.20.01. Rac-beta serine/threonine protein kinase 1p6s Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 83 ± 11 -5.7
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 3 4jch Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.2 88 ± 1 -6.0
2.4.16.01. Alpha-insect toxin LqhaIT 2yeo Leiurus quinquestriatus hebraeus Secreted 1 0 3.5 ± 0.8 43 ± 13 -5.9
2.1.24.01. Pore-forming peptide ameobapore A 1of9 Entamoeba histolytica Undefined 1 0 1.5 ± 1.0 13 ± 18 -2.3
2.2.07.02. Factor H binding protein 1ys5 Neisseria meningitidis Bact. Gram-neg outer 1 0 3.5 ± 2.6 84 ± 5 -5.6
1.2.25.02. Na,K-ATPase regulatory protein FXYD2 2mkv Homo sapiens Eukaryo. plasma 1 1 30.6 ± 3.0 23 ± 2 -25.9
1.1.79.01. P7 protein (781-809) 2k8j Hepatitis C virus Endoplasm. reticulum 1 1 23.6 ± 5.4 41 ± 4 -16.2
3.1.12.01. Endothelin-1 1edn Homo sapiens Secreted 1 0 4.3 ± 1.2 71 ± 25 -5.4
2.2.34.07. Asteropsin D 2lzy Asteropus sp. Secreted 1 0 4.7 ± 1.5 49 ± 29 -3.0
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform 1e7u Sus scrofa Eukaryo. plasma 1 0 2.5 ± 0.9 85 ± 3 -4.7
1.2.33.02. Monoamine oxidase A 2z5x Homo sapiens Mitochon. outer 1 1 31.0 ± 2.1 17 ± 1 -21.4
2.1.01.01. Ammodytin L1 isoform 3ux7 Vipera ammodytes meridionalis Secreted 1 0 2.7 ± 0.3 82 ± 1 -13.2
2.1.08.01. Cytochrome c peroxidase 1nml Marinobacter hydrocarbonoclasticus Bact. Gram-neg inner 1 0 2.2 ± 0.4 83 ± 0 -7.9
2.1.37.01. Erythrocyte membrane protein 1 2xu0 Plasmodium falciparum Eukaryo. plasma 1 0 3.3 ± 6.0 75 ± 45 -3.2
1.1.01.03. Glucagon receptor, full-length, structure 1 5xez Homo sapiens Eukaryo. plasma 1 7 30.6 ± 1.0 12 ± 1 -55.2
2.3.12.01. Myotubularin-related protein 2, monomer 1zvr Homo sapiens Endosome 1 0 3.1 ± 0.4 89 ± 8 -5.0
2.4.16.04. Floral defensin-like protein 1 1n4n Petunia hybrida Secreted 1 0 1.8 ± 0.8 6 ± 9 -3.8
1.3.14.01. Fatty Acid Transporter FadL, F3E, open channel 3pgu Escherichia coli Bact. Gram-neg outer 1 14 25.2 ± 1.5 1 ± 1 -51.5
1.1.01.02. Opsin, complex with arrestin peptide 4pxf Bos taurus Eukaryo. plasma 1 7 31.6 ± 0.9 8 ± 1 -80.1
2.1.03.01. Alpha-toxin (PHLC1_CLOPE), closed state (inactive) 1gyg Clostridium perfringens Secreted 1 0 6.1 ± 2.0 75 ± 6 -5.9
2.2.35.01. Pneumolysin, structure 7 4zgh Streptococcus pneumoniae Secreted 1 0 5.0 ± 2.5 24 ± 25 -4.9
1.2.32.01. Cytochrome P450 2C5, different conformation 1dt6 Oryctolagus cuniculus Endoplasm. reticulum 1 0 7.3 ± 1.0 13 ± 7 -8.8
2.3.18.02. Phthiocerol/phthiodiolone dimycocerosyl transferase 1q9j Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 6.7 ± 2.2 25 ± 6 -5.2
2.1.01.03. Phospholipase A2 group XIII 4aup Tuber borchii Secreted 1 0 3.7 ± 0.7 63 ± 6 -7.7
2.3.10.01. Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 3s2u Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 6.8 ± 0.9 60 ± 2 -8.3
2.2.11.01. Synaptotagmin-7, C2A- and C2B-domains 6ank Rattus norvegicus Eukaryo. plasma 1 0 2.3 ± 0.6 66 ± 6 -5.2
3.1.07.02. Juxtamembrane peptide (657-683) of protein gp160 2me1 Human immunodeficiency virus type 1 Endosome 1 0 7.7 ± 3.8 82 ± 1 -15.0
3.2.03.01. Maurocalcine 1s6w Scorpio maurus Secreted 1 0 1.8 ± 1.6 89 ± 21 -2.3
3.2.10.01. PawS derived peptide 7 2lwu Designed proteins Undefined 1 0 2.0 ± 1.4 81 ± 10 -3.0
2.2.41.01. Alpha-defensin 5 1zmp Homo sapiens Secreted 1 0 4.2 ± 1.6 84 ± 14 -2.8
3.1.28.08. Ocellatin-F1 5ua8 Leptodactylus labyrinthicus Secreted 1 0 6.1 ± 0.8 71 ± 7 -10.0
1.1.110.01. Apolipoprotein N-acyl transferase, structure 2 5n6m Escherichia coli Bact. Gram-neg inner 1 8 28.2 ± 1.6 6 ± 1 -63.5
1.2.32.01. Cytochrome P450 1B1 3pm0 Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 0.7 79 ± 1 -7.0
2.3.06.01. Bile-salt activated lipase, structure 2 1jmy Homo sapiens Secreted 1 0 5.0 ± 1.4 85 ± 9 -5.3
2.4.51.01. Heme acquisition protein HasA 4jet Yersinia pestis Secreted 1 0 4.8 ± 0.9 29 ± 2 -7.0
1.1.01.02. Melanocortin-4 receptor model (inactive state) with antagonist AGRP 2iqv Homo sapiens Eukaryo. plasma 1 7 31.9 ± 1.1 19 ± 0 -49.1
2.4.07.01. PX domain of vacuolar morphogenesis protein VAM7 1kmd Saccharomyces cerevisiae Vacuole 1 0 3.4 ± 1.2 76 ± 8 -7.8
2.2.34.02. M-theraphotoxin-Gr1a 1lu8 Grammostola rosea (Chilean rose tarantula) Secreted 1 0 2.8 ± 0.9 69 ± 7 -7.2
2.2.41.01. Chimeric beta-defensin 2/3 2lxo Designed proteins Undefined 1 0 3.6 ± 0.8 56 ± 14 -5.6
1.1.35.01. Sodium/proton antiporter 1 (NhaA) 1zcd Escherichia coli Bact. Gram-neg inner 1 14 28.4 ± 1.4 2 ± 2 -78.6
1.3.19.02. Alginate export protein, AlgE, conformation 6 5d5d Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.4 ± 1.2 4 ± 1 -67.1
2.2.41.02. Toxin APETx1 1wqk Anthopleura elegantissima (Sea anemone) Secreted 1 0 4.0 ± 1.4 32 ± 18 -7.3
3.2.09.03. Tyrocidine A analogue AC3.27 6b34 Bacillus brevis Secreted 1 0 7.6 ± 1.6 74 ± 9 -9.1
1.1.70.01. CaaX Protease Ste24p 4il3 Saccharomyces mikatae Endoplasm. reticulum 1 7 29.8 ± 1.4 8 ± 0 -63.3
2.1.27.01. Cry2Aa 1i5p Bacillus thuringiensis Secreted 1 0 3.4 ± 1.2 16 ± 12 -7.0
3.4.12.01. Actinomycin D 1a7y Streptomyces antibioticus Secreted 1 0 11.5 ± 0.9 89 ± 11 -12.2
2.2.11.01. Perforin-1 3nsj Mus musculus Vesicle 1 0 3.1 ± 1.0 34 ± 11 -3.3
2.1.29.03. Apolipoprotein C-I, peptide 61-79 1alf Homo sapiens Secreted 1 0 4.1 ± 0.5 86 ± 3 -9.4
1.1.63.01. Type 1 signal peptidase, complex with lipopeptide inhibitor 1t7d Escherichia coli Bact. Gram-neg inner 1 0 3.9 ± 1.0 65 ± 11 -7.6
2.1.01.01. Phospholipase A2, group IB 3elo Homo sapiens Secreted 1 0 0.4 ± 1.5 52 ± 16 -3.5
3.2.05.02. Benenodin-1, state 2 6b5w Asticcacaulis benevestitus Secreted 1 0 3.3 ± 1.6 82 ± 7 -5.8
1.3.20.01. Ferric enterobactin receptor PfeA, structure 1 5mzs Pseudomonas aeruginosa Bact. Gram-neg outer 1 22 24.2 ± 1.0 4 ± 3 -67.1
1.1.01.01. Proteorhodopsin 4hyj Exiguobacterium sibiricum Bact. Gram-pos plas. 1 7 30.0 ± 1.6 15 ± 7 -56.8
2.1.01.01. Snake phospholipase A2 natratoxin, group I 2osh Naja atra Secreted 1 0 2.6 ± 1.6 83 ± 11 -6.1
2.4.16.02. Navitoxin 2rty Nasonia vitripennis (Parasitic wasp) Secreted 1 0 1.2 ± 3.4 90 ± 17 -3.9
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, more complete 4ezk Homo sapiens Eukaryo. plasma 1 0 3.6 ± 0.6 81 ± 2 -5.1
2.2.34.03. Toxin Ado1 1lmr Agriosphodrus dohrni Secreted 1 0 3.1 ± 1.6 60 ± 19 -4.7
2.2.35.01. Intermedilysin - CD59 receptor complex, disulfide-locked mutant 4bik Streptococcus intermedius Secreted 1 0 5.9 ± 3.1 28 ± 43 -6.4
1.1.25.05. Dipeptide permease D 4q65 Escherichia coli Bact. Gram-neg inner 1 14 30.2 ± 0.8 7 ± 1 -101.4
1.1.01.02. Beta-1 adrenergic receptor, inactive, complex with agonist 2y02 Meleagris gallopavo Eukaryo. plasma 1 7 31.4 ± 1.3 2 ± 0 -76.9
3.1.20.01. Alpha-conotoxin PIA 1zlc Conus purpurascens (Purple cone) Secreted 1 0 2.6 ± 1.3 59 ± 16 -4.3
2.2.27.01. C1 domain of protein kinase C delta 1ptr Mus musculus Eukaryo. plasma 1 0 6.6 ± 1.5 19 ± 8 -5.9
3.1.29.03. Prophenin-1 2i1d Sus scrofa Secreted 1 0 4.8 ± 1.9 70 ± 35 -5.9
2.3.06.04. Palmitoyl protein thioesterase 2 1pja Homo sapiens Lysosome 1 0 3.7 ± 1.6 60 ± 15 -4.6
1.3.20.01. Outer membrane cobalamin transporter BtuB, complex with TonB 2gsk Escherichia coli Bact. Gram-neg outer 1 22 23.4 ± 0.7 5 ± 0 -77.5
1.1.10.04. P-glycoprotein, inward-facing conformation 1c 4m1m Mus musculus Eukaryo. plasma 1 12 31.2 ± 1.3 2 ± 1 -90.6
1.1.09.01. Calcium ATPase, E1 state, with macrolide BLS 4ycm Oryctolagus cuniculus Endoplasm. reticulum 1 10 3.2 ± 1.8 21 ± 1 -66.3
2.2.41.01. Spheniscin-2 (bird defensin) 1ut3 Aptenodytes patagonicus Secreted 1 0 3.6 ± 1.6 44 ± 17 -6.2
2.2.35.01. Pneumolysin, structure 1 4qqq Streptococcus pneumoniae Secreted 1 0 4.6 ± 3.7 27 ± 7 -6.8
1.1.08.01. F0 ATP synthase, subunit c, double mutant 1l6t Escherichia coli Bact. Gram-neg inner 1 2 30.0 ± 4.4 36 ± 3 -28.2
2.4.05.01. Sterol carrier protein 2-like 2 2qzt Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 1.0 ± 2.0 45 ± 12 -3.0
2.2.39.01. Muscarinic m1-toxin1 2vlw Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 3.4 ± 0.9 82 ± 9 -4.9
2.2.11.01. Synaptotagmin-4 1ugk Homo sapiens Eukaryo. plasma 1 0 2.5 ± 1.7 34 ± 11 -3.5
3.4.13.01. T-cell-specific surface glycoprotein CD28, intracellular loop 2nae Mus musculus Eukaryo. plasma 1 0 0.9 ± 10.0 81 ± 3 -6.4
2.3.14.01. Phosphatidylinositol transfer protein sec14p 1aua Saccharomyces cerevisiae Golgi 1 0 8.8 ± 1.1 75 ± 10 -14.3
1.1.01.01. Sensory rhodopsin II, monomer 1h68 Natronomonas pharaonis Archaebac. 1 7 30.3 ± 1.5 15 ± 2 -60.0
2.2.11.01. Protein kinase C eta, C2 domain 2fk9 Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.1 57 ± 6 -5.0
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 5tl8 Naegleria fowleri Endoplasm. reticulum 1 0 6.2 ± 1.2 64 ± 3 -9.7
2.3.06.08. Pancreatic lipase 1bu8 Rattus norvegicus Secreted 1 0 3.5 ± 1.3 87 ± 10 -6.1
3.1.28.04. Esculentin-1A, structure 1 2n6m Pelophylax esculentus Secreted 1 0 7.9 ± 0.4 67 ± 5 -7.9
1.1.52.02. 4-amino-4-deoxy-L-arabinose transferase 5f15 Cupriavidus metallidurans Bact. Gram-neg inner 1 13 29.2 ± 0.7 3 ± 0 -93.8
1.2.04.01. Integrin beta-3, 742-788, 747pY, in water 2ljf Homo sapiens Eukaryo. plasma 1 0 0.6 ± 1.6 62 ± 14 -1.8
3.1.07.02. Transmembrane domain of HIV-1 gp41 (677-716) 6b3u Human immunodeficiency virus type 1 Viral 1 1 31.2 ± 2.2 44 ± 4 -28.2
2.2.34.02. Neurotoxin Hm-3 2mqu Heriaeus melloteei Secreted 1 0 2.4 ± 0.6 75 ± 11 -7.4
1.2.13.01. Intrinsic membrane protein PufX 2ita Rhodobacter sphaeroides Bact. Gram-neg inner 1 1 32.2 ± 5.1 33 ± 1 -22.8
2.2.06.02. Adipocyte lipid-binding protein 1a18 Mus musculus Eukaryo. plasma 1 0 3.7 ± 0.8 47 ± 7 -7.4
1.1.117.01. DHHC20 palmitoyltransferase, structure 1 6bml Homo sapiens Golgi 1 4 29.0 ± 2.6 29 ± 1 -52.1
2.1.42.01. Putative carnobacteriocin-B2 immunity protein 1tdp Carnobacterium maltaromaticum Secreted 1 0 4.4 ± 0.5 90 ± 9 -4.3
2.1.48.01. Glycerol dehydrogenase 1kq3 Thermotoga maritima Undefined 1 0 2.5 ± 1.8 80 ± 5 -4.3
2.2.09.03. Surface layer protein 1l0q Methanosarcina mazei (Methanosarcina frisia) Archaebac. 1 0 3.1 ± 0.9 81 ± 7 -5.1
1.3.19.01. Porin OpdF 3szd Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 22.0 ± 1.6 3 ± 0 -60.3
1.1.01.02. Free fatty acid receptor 1, structure 1 4phu Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 10 ± 1 -59.2
2.2.05.01. Plastocyanin 1b3i Prochlorothrix hollandica Thylakoid 1 0 2.8 ± 1.4 43 ± 18 -4.4
3.1.26.01. Pleurocidin 1z64 Pseudopleuronectes americanus Secreted 1 0 5.4 ± 1.3 87 ± 18 -12.8
3.1.18.02. Phenol-soluble modulin beta-2 5kgz Staphylococcus aureus Secreted 1 0 6.2 ± 2.5 55 ± 7 -6.2
2.4.15.01. Protein Nef (HIV HV1LW) 2nef Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 6.3 ± 1.4 73 ± 3 -7.9
1.2.32.01. Cytochrome P450 2A6 1z10 Homo sapiens Endoplasm. reticulum 1 0 5.0 ± 1.7 44 ± 18 -9.5
1.2.22.01. Bcl-2-like protein 1, complex with alpha-beta-foldamer 4a1u Homo sapiens Mitochon. outer 1 0 5.8 ± 0.3 26 ± 5 -5.7
2.1.60.01. Potassium channel toxin ShK 1roo Stoichactis helianthus Secreted 1 0 1.2 ± 1.2 46 ± 8 -3.7
1.1.25.02. Lactose permease LacY, structure 6 5gxb Escherichia coli Bact. Gram-neg inner 1 12 33.8 ± 1.5 1 ± 1 -89.6
2.4.06.01. StAR-related lipid transfer protein 13 2pso Homo sapiens Eukaryo. plasma 1 0 3.1 ± 4.0 77 ± 27 -4.6
2.2.26.01. RUN and FYVE domain-containing protein 1 2yw8 Homo sapiens Endosome 1 0 0.7 ± 3.4 48 ± 38 -2.8
2.4.16.06. Mytilin-B 2eem Mytilus edulis (Blue mussel) Secreted 1 0 3.6 ± 1.4 76 ± 8 -3.2
2.3.27.01. Dihydrofolate reductase 3nzb Pneumocystis carinii Undefined 1 0 3.9 ± 1.9 72 ± 10 -5.9
1.3.10.01. Oligogalacturonate-specific porin KdgM 4fqe Dickeya dadantii Bact. Gram-neg outer 1 12 22.2 ± 1.5 2 ± 1 -42.1
2.2.06.02. Fatty acid-binding protein, epidermal 4azp Mus musculus Eukaryo. plasma 1 0 4.2 ± 2.4 57 ± 11 -5.5
3.1.21.01. Cecropin-P1 2n92 Ascaris suum Secreted 1 0 1.6 ± 3.4 90 ± 0 -4.1
1.1.28.03. SecDF secretion protein, structure 1 5xam Deinococcus radiodurans Bact. Gram-neg inner 1 12 30.2 ± 1.0 4 ± 1 -83.1
1.2.32.01. Cytochrome P450 2E1 3e6i Homo sapiens Endoplasm. reticulum 1 0 8.3 ± 2.0 49 ± 8 -14.2
2.2.41.03. Big defensin, segment 43-72 2rq2 Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 1 25.6 ± 4.4 18 ± 2 -13.5
2.2.39.01. Muscarinic m1-toxin1, chimeric sequence 3fev Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 5.5 ± 1.5 76 ± 8 -6.3
2.2.20.01. PH domain of muscle M-line assembly protein unc-89 1fho Caenorhabditis elegans Eukaryo. plasma 1 0 2.3 ± 1.2 25 ± 14 -4.3
3.1.07.02. Juxtamembrane peptide (671-697) of protein gp160 2me4 Human immunodeficiency virus type 1 Endosome 1 0 7.9 ± 2.9 81 ± 4 -14.0
3.1.15.04. Bacteriocin plantaricin K (PlnK) 2keg Lactobacillus plantarum Secreted 1 0 3.3 ± 1.1 83 ± 11 -8.4
3.1.05.13. Cullin3-derived peptides 2myl Designed proteins Undefined 1 0 3.4 ± 1.2 82 ± 21 -4.4
1.3.17.01. Filamentous hemagglutinin transporter FhaC, structure 2 4ql0 Bordetella pertussis Bact. Gram-neg outer 1 16 23.2 ± 0.9 10 ± 0 -62.7
2.2.11.01. Synaptotagmin-1, C2B domain (Calcium-bound) 4v11 Homo sapiens Eukaryo. plasma 1 0 1.6 ± 2.3 40 ± 7 -3.2
1.2.38.01. Glycosyltransferase MtgA 3hzs Staphylococcus aureus Bact. Gram-pos plas. 1 0 7.0 ± 1.1 54 ± 9 -14.6
2.3.06.08. Pancreatic lipase-related protein 2 1w52 Equus caballus Secreted 1 0 4.8 ± 0.2 83 ± 0 -12.7
2.3.25.02. Lipase 5mal Streptomyces rimosus Secreted 1 0 3.9 ± 0.8 64 ± 20 -6.3
1.2.44.01. Amyloid beta A4 protein (peptide 688-704), in water 2mj1 Homo sapiens Eukaryo. plasma 1 0 9.4 ± 3.4 38 ± 11 -7.4
1.2.32.01. Cytochrome P450 17A1, structure 1 3swz Homo sapiens Endoplasm. reticulum 1 0 4.2 ± 1.6 56 ± 3 -8.4
2.1.01.01. Snake phospholipase A2, group II, RVV-VD 1vip Vipera russelli Secreted 1 0 4.4 ± 0.8 85 ± 11 -9.5
3.1.20.01. Conotoxin pc16a 2ler Conus pictus Secreted 1 0 4.0 ± 1.0 64 ± 7 -4.1
1.1.09.01. Plasma membrane ATPase 2, E1-ATP state 5ksd Arabidopsis thaliana Eukaryo. plasma 1 10 30.8 ± 1.2 4 ± 1 -59.3
1.1.01.03. Glucagon-like peptide 1 receptor with Gs-protein 6b3j Homo sapiens Eukaryo. plasma 1 7 31.0 ± 1.4 15 ± 3 -58.7
2.2.33.01. Hevein 1q9b Hevea brasiliensis (Para rubber tree) Secreted 1 0 1.0 ± 1.0 90 ± 11 -1.8
3.2.07.01. N-terminal beta-hairpin of ubiquitin 1e0q Bos taurus Undefined 1 0 3.5 ± 0.4 85 ± 0 -7.8
2.1.05.02. Farnesyl diphosphate synthase (Geranyltranstransferase) 1rqj Escherichia coli Bact. Gram-neg inner 1 0 3.3 ± 0.7 87 ± 3 -7.7
1.3.17.02. BamACDE subcomplex, structure 2 5d0q Escherichia coli Bact. Gram-neg outer 1 16 22.8 ± 1.1 10 ± 0 -44.9
1.1.01.02. Neurotensin receptor type 1, structure 3 4xes Rattus norvegicus Eukaryo. plasma 1 7 31.8 ± 1.4 5 ± 1 -68.3
1.2.18.01. Sortase B 1rz2 Bacillus anthracis Bact. Gram-pos plas. 1 0 3.0 ± 0.6 82 ± 6 -5.8
2.1.01.01. Phospholipase A2 homolog, ammodytin L 3dih Vipera ammodytes ammodytes Secreted 1 0 5.0 ± 0.4 82 ± 5 -14.4
2.3.25.01. Acyloxyacyl hydrolase, structure 2 5w7d Mus musculus Secreted 1 0 1.6 ± 0.8 82 ± 12 -3.6
1.1.26.03. Sialic acid symporter 5nv9 Proteus mirabilis Bact. Gram-neg inner 1 13 29.8 ± 0.8 18 ± 0 -93.0
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 8 2zbg Oryctolagus cuniculus Endoplasm. reticulum 1 10 30.0 ± 1.7 21 ± 0 -66.5
1.2.11.02. Capsid protein G8P, monomer 2xkm Bacteriophage Pf1 Secreted 1 1 29.2 ± 4.6 34 ± 1 -23.0
3.2.05.02. Lassomycin 2mai Lentzea kentuckyensis Secreted 1 0 3.1 ± 1.0 72 ± 9 -4.7
2.2.34.01. Omega-conotoxin SVIB 1mvj Conus striatus Secreted 1 0 1.1 ± 2.1 20 ± 24 -2.1
2.3.02.01. Phospholipase C-beta isoform 2 2zkm Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.9 38 ± 12 -3.6
2.2.34.02. Mu-agatoxin-Aa1a 1eit Agelenopsis aperta Secreted 1 0 1.3 ± 1.5 59 ± 10 -3.1
1.2.03.05. Prolactin receptor (230-264) 2n7i Homo sapiens Eukaryo. plasma 1 1 31.8 ± 4.1 12 ± 8 -21.2
1.1.39.04. Nickel/cobalt transporter CbiM 4m58 Thermoanaerobacter tengcongensis Bact. Gram-pos plas. 1 7 29.8 ± 0.9 18 ± 2 -59.8
2.3.06.09. Mycobacterial lipase 3aja Mycobacterium smegmatis Secreted 1 0 6.0 ± 1.0 28 ± 10 -6.7
3.2.05.02. Rubrivinodin 5oqz Rubrivivax gelatinosus Secreted 1 0 4.0 ± 1.4 84 ± 11 -6.0
1.2.32.01. Lanosterol 14-alpha demethylase (CYP51), with lanosterol 5eqb Saccharomyces cerevisiae Endoplasm. reticulum 1 1 29.8 ± 0.9 39 ± 2 -34.5
2.4.16.03. Toxin I5a 1sis Buthus eupeus Secreted 1 0 3.1 ± 1.4 74 ± 16 -4.4
3.1.21.01. Aedesin 2mmm Aedes aegypti (Yellowfever mosquito) Secreted 1 1 20.8 ± 0.8 11 ± 3 -12.3
1.2.32.01. Cytochrome P450 24a1 (1,25-dihydroxyvitamin D(3) 24-hydroxylase) 3k9v Rattus norvegicus Mitochon. inner 1 0 6.6 ± 1.0 49 ± 6 -9.6
3.1.11.01. Neuropeptide Y 1ron Homo sapiens Secreted 1 0 7.9 ± 1.6 74 ± 10 -8.6
1.1.20.03. Claudin-4 5b2g Homo sapiens Eukaryo. plasma 1 4 35.6 ± 2.1 7 ± 2 -45.8
1.3.11.01. Serine protease EspP, post-cleavage structure 2qom Escherichia coli Bact. Gram-neg outer 1 12 25.1 ± 1.6 6 ± 7 -55.9
2.3.06.01. Bile-salt activated lipase, conformation 1 1aql Bos taurus Secreted 1 0 5.7 ± 1.1 78 ± 7 -9.6
2.3.06.01. Carboxylic ester hydrolase, open state 4be9 Ophiostoma piceae Secreted 1 0 8.7 ± 0.4 88 ± 2 -30.9
2.4.07.01. Bud emergence protein 1 2v6v Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.1 ± 1.2 75 ± 6 -5.1
1.1.34.01. Mitochondrial ADP-ATP carrier, with carboxyatractyloside 2c3e Bos taurus Mitochon. inner 1 6 30.0 ± 1.0 4 ± 2 -44.0
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 3 4ut6 Dengue virus Viral 1 0 6.2 ± 3.0 19 ± 15 -5.4
1.1.01.01. Proton-pumping rhodopsin-2 from algae 3am6 Acetabularia acetabulum Eukaryo. plasma 1 7 31.2 ± 1.6 10 ± 1 -65.4
2.1.15.02. ADP-ribosylation factor-binding protein GGA2 1mhq Homo sapiens Golgi 1 0 4.2 ± 1.2 74 ± 5 -4.1
3.1.28.03. Bombinin-H5 2ap8 Bombina variegata (Yellow-bellied toad) Secreted 1 0 8.6 ± 4.2 77 ± 3 -10.6
3.4.07.01. Antimicrobial cationic cyclic hexapeptide 1qvl Designed proteins Undefined 1 0 4.2 ± 1.6 84 ± 15 -6.8
1.1.38.01. H+-driven MATE exporter, outward-open, with nonpeptide inhibitor 3vvp Pyrococcus furiosus Archaebac. 1 12 29.8 ± 1.3 8 ± 0 -79.6
1.3.21.01. Outer membrane usher protein FimD, complex with FimC-FimH 3rfz Escherichia coli Bact. Gram-neg outer 1 24 23.8 ± 0.8 5 ± 0 -65.1
1.1.01.02. P2Y purinoceptor 12, structure 1 4ntj Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 9 ± 0 -79.8
3.1.14.01. Eledoisin 1mxq Eledone cirrhosa (Curled octopus) Secreted 1 0 2.9 ± 1.7 59 ± 19 -5.0
3.1.02.02. Potassium voltage-gated channel protein Shaker, peptide 378-397 1ho2 Drosophila melanogaster Eukaryo. plasma 1 0 3.9 ± 1.2 88 ± 16 -7.5
3.1.03.08. Lipid interacting helix (227-245) of digalactosyldiacylglycerol synthase 2l7c Arabidopsis thaliana Chloroplast outer 1 0 3.3 ± 3.6 88 ± 1 -6.0
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 1 3mok Pseudomonas aeruginosa Secreted 1 0 4.5 ± 0.7 37 ± 7 -6.7
1.1.26.01. Leucine transporter LeuT, inward-facing conformation 3tt3 Aquifex aeolicus Bact. Gram-neg inner 1 12 27.4 ± 1.6 9 ± 0 -89.1
1.1.01.03. Calcitonin receptor-Gs protein complex 5uz7 Homo sapiens Eukaryo. plasma 1 7 30.2 ± 1.0 13 ± 0 -50.9
2.1.14.01. Peroxisomal targeting signal 1 receptor 1fch Homo sapiens Peroxisome 1 0 6.9 ± 1.2 54 ± 3 -6.7
2.2.41.01. Oral alpha defensin 1 2k1i Macaca mulatta Secreted 1 0 0.9 ± 3.2 70 ± 15 -2.2
2.3.22.01. Uncharacterized protein 1rtt Pseudomonas aeruginosa Undefined 1 0 3.1 ± 2.5 70 ± 22 -4.1
2.2.04.01. 9-cis-epoxycarotenoid dioxygenase 1, chloroplastic 3npe Zea mays Thylakoid 1 0 6.0 ± 0.1 30 ± 5 -11.1
3.4.02.01. Actagardine, structure in acetonitrile solution 1aj1 Actinoplanes liguriae Secreted 1 0 3.0 ± 1.1 90 ± 11 -5.7
2.3.06.06. Triacylglycerol lipase, closed state 2 5ap9 Humicola lanuginosa Secreted 1 0 5.7 ± 0.4 79 ± 5 -6.1
3.1.02.01. Second intracellular loop (118-149) of alpha-2A adrenergic receptor 1hod Homo sapiens Eukaryo. plasma 1 0 3.9 ± 4.1 75 ± 3 -7.2
1.3.22.01. VDAC-1 channel, structure 4 5xdn Homo sapiens Mitochon. outer 1 19 24.2 ± 0.8 4 ± 0 -49.5
2.2.34.11. Kalata-B8 2b38 Oldenlandia affinis Secreted 1 0 5.5 ± 1.0 88 ± 12 -5.6
3.1.07.02. Juxtamembrane peptide (662-683) of protein gp41 2pv6 Human immunodeficiency virus type 1 Endosome 1 0 6.7 ± 0.6 82 ± 2 -13.5
2.4.16.02. Termicin 1mm0 Pseudacanthotermes spiniger Secreted 1 0 4.2 ± 0.5 81 ± 3 -3.3
3.1.05.03. LAK160-P10 2l99 Designed proteins Undefined 1 0 3.9 ± 2.6 84 ± 0 -5.0
2.4.43.01. Cell wall anchor protein of the T6SS system 4b62 Pseudomonas aeruginosa Bact. Gram-neg outer 1 0 2.8 ± 2.5 46 ± 36 -4.6
3.1.02.02. S5P linker peptide (570-611) of HERG K+ channel 1ujl Homo sapiens Eukaryo. plasma 1 0 4.6 ± 0.3 89 ± 7 -7.6
3.1.30.01. Lactoferricin peptide (36-59) 5id5 Sus scrofa Secreted 1 0 7.4 ± 1.0 87 ± 9 -6.2
1.1.109.01. NADPH oxidase 5 (NOX5) 5o0t Cylindrospermum stagnale Bact. Gram-neg inner 1 6 29.4 ± 1.4 10 ± 4 -59.6
1.2.03.02. Cytotoxic T-lymphocyte protein 4 1dqt Mus musculus Eukaryo. plasma 1 0 3.4 ± 1.6 64 ± 4 -5.3
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 7 3ar9 Oryctolagus cuniculus Endoplasm. reticulum 1 10 29.0 ± 0.9 20 ± 0 -73.8
1.2.16.01. Pulmonary surfactant-associated protein C 1spf Sus scrofa Secreted 1 1 31.7 ± 3.3 21 ± 0 -32.0
2.2.11.01. Rabphilin-3A, C2A domain 2chd Rattus norvegicus Eukaryo. plasma 1 0 2.9 ± 1.6 57 ± 19 -2.7
3.1.07.01. Fusion peptide of protein gp41, hybrid sequences 5nvp Human immunodeficiency virus type 1 Endosome 1 0 3.9 ± 2.0 68 ± 6 -8.1
2.2.33.01. Antimicrobial Peptide AMP-1.1a 2kus Stellaria media Secreted 1 0 1.5 ± 0.9 18 ± 27 -2.7
3.2.01.07. Transthyretin-derived peptide 5hpp Designed proteins Undefined 1 0 2.7 ± 1.6 83 ± 6 -5.2
1.3.15.02. CymA protein, conformation 1 4d51 Klebsiella oxytoca Bact. Gram-neg outer 1 14 25.0 ± 1.7 2 ± 1 -44.8
1.1.01.02. P2Y purinoceptor 1, conformation 1 4xnv Homo sapiens Eukaryo. plasma 1 7 32.6 ± 1.7 6 ± 1 -70.3
1.2.27.01. Fst toxin 2kv5 Enterococcus faecalis Bact. Gram-pos plas. 1 1 26.0 ± 2.9 35 ± 8 -18.9
2.2.22.01. Hydrophobin I 2gvm Hypocrea jecorina Secreted 1 0 5.3 ± 1.1 27 ± 18 -8.7
2.2.39.01. Cytotoxin-1, minor form 5lue Naja naja oxiana Secreted 1 0 5.7 ± 0.8 87 ± 13 -7.6
2.1.01.01. Myotoxin II 1xxs Bothrops moojeni Secreted 1 0 4.5 ± 1.2 76 ± 10 -5.3
3.2.04.03. Peptide leucine arginine 2m3n Lithobates pipiens Secreted 1 0 4.7 ± 0.6 83 ± 5 -5.7
2.1.20.01. Prothrombin, structure 2 5edm Homo sapiens Eukaryo. plasma 1 0 4.2 ± 4.2 31 ± 6 -10.1
2.4.13.01. Protein Osh1 5h2d Kluyveromyces lactis Vacuole 1 0 0.4 ± 2.4 71 ± 26 -2.7
3.1.15.03. Bacteriocin peptide plantaricin E (PlnE) 2jui Lactobacillus plantarum Secreted 1 0 4.3 ± 4.2 79 ± 4 -5.0
1.1.07.01. Nitric oxide reductase 3ayf Bacillus stearothermophilus Bact. Gram-pos plas. 1 14 31.6 ± 0.8 8 ± 0 -109.3
3.1.19.01. Harzianin 6, structure 1 5m9y Trichoderma pseudokoningii Secreted 1 0 9.4 ± 1.2 89 ± 10 -9.4
1.2.57.01. Reticulon-4 2ko2 Mus musculus Endoplasm. reticulum 1 0 2.5 ± 0.3 83 ± 1 -6.2
2.2.35.01. Perfringolysin 1pfo Clostridium perfringens Secreted 1 0 4.4 ± 2.0 38 ± 12 -6.7
2.1.60.03. Pseudecin, conformation 1 2ddb Pseudechis porphyriacus Secreted 1 0 4.8 ± 0.7 90 ± 3 -5.4
1.3.01.02. Outer membrane protein X (OMPX) 1qj8 Escherichia coli Bact. Gram-neg outer 1 8 23.6 ± 2.8 12 ± 5 -30.7
3.1.02.01. Apelin receptor, peptide 1-55 2low Homo sapiens Eukaryo. plasma 1 1 26.4 ± 5.1 35 ± 2 -16.7
2.2.34.01. Delta conotoxin TxVIA 1fu3 Conus textile Secreted 1 0 6.5 ± 1.8 25 ± 18 -8.3
3.2.01.06. Lactoferricin B, peptide 10-19 1y5c Bos taurus Secreted 1 0 2.2 ± 1.2 54 ± 11 -3.4
1.1.01.02. Dopamine D3 receptor 3pbl Homo sapiens Eukaryo. plasma 1 7 33.0 ± 1.8 8 ± 1 -56.6
1.1.34.01. Mitochondrial ADP-ATP carrier 1okc Bos taurus Mitochon. inner 1 6 29.5 ± 1.7 14 ± 1 -44.6
3.1.07.03. Hemagglutinin, fusion peptide 346-365, G1S 1xop Influenza virus Viral 1 0 6.3 ± 0.5 70 ± 13 -11.0
2.2.34.02. Toxin GsMTx2 1lup Grammostola rosea (Chilean rose tarantula) Secreted 1 0 3.8 ± 1.1 90 ± 8 -4.8
3.1.01.03. N-terminal helix of prion-like protein doppel 1z65 Mus musculus Eukaryo. plasma 1 1 21.0 ± 6.2 8 ± 4 -13.2
1.1.26.01. MhsT transporter, inward-facing state 4us3 Bacillus halodurans Bact. Gram-pos plas. 1 11 29.8 ± 0.8 11 ± 1 -87.1
3.1.01.01. Kalata-B3/B6 propeptide 1wn8 Oldenlandia affinis Secreted 1 0 3.6 ± 1.2 81 ± 22 -8.4
1.1.22.02. YaxA toxin 6ek7 Yersinia enterocolitica Secreted 1 0 8.6 ± 6.4 45 ± 36 -7.2
1.3.04.03. Lipid A acylase PagP 3gp6 Escherichia coli Bact. Gram-neg outer 1 8 24.7 ± 1.5 40 ± 1 -32.5
2.3.13.04. Glutathione peroxidase 8 3kij Homo sapiens Endoplasm. reticulum 1 0 3.4 ± 2.7 56 ± 16 -6.1
2.2.39.01. Cardiotoxin VI 1ug4 Naja atra Secreted 1 0 6.4 ± 0.9 62 ± 4 -12.2
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, mutant 1 2mb1 Zaire ebolavirus Viral 1 0 3.8 ± 1.8 53 ± 34 -4.5
3.2.06.01. Paralytic peptide 1 1hrl Manduca sexta Secreted 1 0 6.5 ± 0.6 51 ± 6 -6.2
2.2.12.01. Mite group 2 allergen Der p 2 1ktj Dermatophagoides pteronyssinussearch Secreted 1 0 1.4 ± 1.3 65 ± 9 -3.2
1.3.09.01. Lipid A deacylase LpxR 3fid Salmonella enterica Bact. Gram-neg outer 1 12 25.6 ± 2.0 24 ± 0 -58.6
2.1.10.01. Ceramide-1-phosphate transfer protein 4k8n Homo sapiens Eukaryo. plasma 1 0 7.0 ± 1.0 81 ± 4 -10.6
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), structure 2 5fsa Candida albicans Endoplasm. reticulum 1 0 9.0 ± 0.8 61 ± 2 -18.0
2.3.06.06. Lipase 2 1gz7 Candida rugosa Secreted 1 0 4.8 ± 1.3 87 ± 10 -8.5
3.1.15.01. Enterocin-HF 2n4k Enterococcus faecium Secreted 1 0 4.8 ± 3.5 82 ± 4 -4.8
2.2.20.01. Rho GTPase-activating protein 27 3pp2 Homo sapiens Eukaryo. plasma 1 0 2.5 ± 2.2 72 ± 14 -3.4
1.2.43.01. Envelope glycoprotein, Zika virus, structure 3 5jhm Zika virus Viral 1 0 6.6 ± 2.4 11 ± 8 -4.9
2.2.21.03. Interleukin-36 receptor antagonist protein 1md6 Mus musculus Secreted 1 0 3.8 ± 0.4 40 ± 3 -6.5
2.2.20.01. SET binding factor 1 1v5u Mus musculus Eukaryo. plasma 1 0 4.2 ± 1.5 59 ± 10 -5.3
1.1.107.01. Scavenger receptor B-1 5ktf Mus musculus Eukaryo. plasma 1 1 30.0 ± 2.8 41 ± 1 -25.1
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 4 3spw Saccharomyces cerevisiae Golgi 1 0 7.3 ± 1.1 60 ± 9 -4.5
2.4.16.01. Beta-toxin Cn5 2kja Centruroides noxius (Mexican scorpion) Secreted 1 0 4.1 ± 1.1 73 ± 6 -7.0
3.1.07.03. Antimicrobial peptide derived from hemagglutinin 2l24 Influenza virus Undefined 1 0 8.7 ± 1.3 75 ± 10 -12.6
1.3.20.01. Enantio-pyochelin receptor FetA 3qlb Pseudomonas fluorescens Bact. Gram-neg outer 1 22 23.4 ± 0.8 7 ± 0 -75.3
2.2.11.01. Extended synaptotagmin-2, SMP-C2A-C2B domains 4p42 Homo sapiens Eukaryo. plasma 1 0 5.5 ± 2.8 67 ± 6 -3.3
1.1.02.06. Light-harvesting complex CP29 3pl9 Spinacia oleracea Thylakoid 1 3 29.8 ± 1.6 2 ± 2 -66.6
3.1.19.01. Zervamicin IIb 1ih9 Emericellopsis salmosynnemata Secreted 1 0 11.5 ± 2.0 74 ± 10 -12.3
2.2.34.07. Asteropsin E 2m3j Asteropus sp. Secreted 1 0 4.5 ± 1.1 65 ± 7 -3.6
1.3.22.01. VDAC-1 channel, structure 2 (NMR) 2k4t Homo sapiens Mitochon. outer 1 19 22.0 ± 1.5 1 ± 1 -34.8
2.2.41.01. Gallinacin-2 2lg5 Gallus gallus Secreted 1 0 8.0 ± 1.2 62 ± 6 -8.2
1.1.49.01. ATP-dependent zinc metalloprotease FtsH 1lv7 Escherichia coli Bact. Gram-neg inner 1 0 2.1 ± 1.0 80 ± 11 -4.3
2.1.37.01. Erythrocyte membrane protein 1 variant 3c64 Plasmodium falciparum Eukaryo. plasma 1 0 5.3 ± 2.5 52 ± 3 -9.6
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-bound 1o7k Homo sapiens Endosome 1 0 15.2 ± 1.7 60 ± 15 -18.4
2.4.16.04. Defensin 2 (PDF1) 2gl1 Vigna radiata (Mung bean) Secreted 1 0 2.8 ± 0.6 6 ± 4 -5.7
2.3.13.04. Glutathione peroxidase-like protein 2vup Trypanosoma brucei Undefined 1 0 3.0 ± 1.7 84 ± 7 -4.1
1.3.14.01. Fatty Acid Transporter FadL, delS3, open channel 2r88 Escherichia coli Bact. Gram-neg outer 1 14 24.0 ± 1.4 6 ± 2 -53.8
2.3.06.01. Bile-salt activated lipase, conformation 3 2bce Bos taurus Secreted 1 0 5.3 ± 0.8 74 ± 6 -7.0
2.2.39.02. Mambalgin-1 5dz5 Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 6.2 ± 0.1 69 ± 1 -5.6
2.3.06.02. Antigen 85c, conformation 2 4qdu Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 5.3 ± 2.4 87 ± 16 -5.2
3.1.28.03. Maximin-4 2mhw Bombina maxima Secreted 1 0 4.4 ± 1.0 75 ± 3 -6.3
1.1.12.15. TRPV6 channel, monomer, structure 2 5woa Rattus norvegicus Eukaryo. plasma 1 6 30.2 ± 1.6 12 ± 6 -85.2
3.1.07.01. Probable fusion peptide (93-126, 138-160) of protein gp41 2mk3 Human immunodeficiency virus type 1 Endosome 1 2 20.8 ± 0.5 18 ± 1 -13.2
3.2.01.03. Tachyplesin-1 2rtv Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 4.2 ± 0.4 88 ± 3 -6.8
3.1.05.03. LAK160-P7 2l96 Designed proteins Undefined 1 0 1.4 ± 0.9 88 ± 5 -2.7
2.2.41.01. Alpha-defensin 6 1zmq Homo sapiens Secreted 1 0 3.7 ± 1.6 76 ± 18 -3.6
3.1.28.07. Hylin-A1 analogs 5j6v Hypsiboas albopunctatus Secreted 1 0 21.2 ± 2.2 33 ± 16 -10.4
1.1.110.01. Apolipoprotein N-acyl transferase, structure 3 5vrg Escherichia coli Bact. Gram-neg inner 1 8 30.2 ± 1.2 2 ± 1 -70.7
2.1.49.01. cGMP-specific 3',5'-cyclic phosphodiesterase 1rkp Homo sapiens Eukaryo. plasma 1 0 5.0 ± 1.6 61 ± 11 -5.2
1.2.32.01. Cytochrome P450 2A13 2p85 Homo sapiens Endoplasm. reticulum 1 0 4.9 ± 0.4 47 ± 2 -10.0
2.1.03.01. Alpha-toxin (PHLC1_CLOPE), open state 1ca1 Clostridium perfringens Secreted 1 0 2.9 ± 1.0 89 ± 4 -9.3
2.4.51.01. Heme acquisition protein HasA, apoprotein 4jes Yersinia pestis Secreted 1 0 5.2 ± 0.3 40 ± 2 -9.6
1.1.10.08. Multidrug resistance protein 1 6c0v Homo sapiens Eukaryo. plasma 1 12 32.6 ± 1.2 5 ± 0 -105.0
2.1.33.01. DrrA protein, PtdIns(4) binding domain, from different strain 3l0m Legionella pneumophila Vacuole 1 0 3.7 ± 4.2 44 ± 7 -4.8
3.4.09.01. Granin, cyclic analogue 1n2y Bos taurus Secreted 1 0 1.9 ± 2.1 71 ± 16 -3.4
3.2.11.01. Peptide NC_cEE_D1 5kx2 Designed proteins Undefined 1 0 4.9 ± 1.9 70 ± 14 -4.6
1.3.17.02. BamACDE subcomplex, structure 1 5ekq Escherichia coli Bact. Gram-neg outer 1 16 23.4 ± 0.7 18 ± 0 -61.9
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2 2w8d Bacillus subtilis Bact. Gram-pos plas. 1 0 0.0 ± 6.0 83 ± 58 -1.6
2.2.41.02. Toxin APETx2 1wxn Anthopleura elegantissima (Sea anemone) Secreted 1 0 4.9 ± 1.7 33 ± 18 -5.5
3.2.09.03. Tyrocidine A analogue AC3.28 6b35 Bacillus brevis Secreted 1 0 6.3 ± 1.6 79 ± 13 -10.1
1.1.01.02. Sphingosine 1-phosphate receptor 1 3v2y Homo sapiens Eukaryo. plasma 1 7 32.2 ± 1.4 10 ± 0 -65.9
2.1.04.01. Alpha-dioxygenase 1 4hhr Arabidopsis thaliana Endoplasm. reticulum 1 0 10.8 ± 0.1 68 ± 2 -31.4
3.1.27.01. Pardaxin, different conformation 1xc0 Pardachirus marmoratus Secreted 1 1 20.8 ± 5.4 42 ± 2 -9.6
3.4.12.01. Actinomycin Z3 1a7z Streptomyces antibioticus Secreted 1 0 10.0 ± 1.3 76 ± 24 -9.6
2.2.11.01. Synaptotagmin-1, C2A domain (Calcium free) 3f00 Homo sapiens Eukaryo. plasma 1 0 1.4 ± 1.5 29 ± 18 -3.3
2.2.11.01. Synaptotagmin-like protein 4 3fdw Homo sapiens Vesicle 1 0 3.0 ± 2.0 71 ± 17 -3.6
2.1.29.01. Apolipoprotein E 2l7b Homo sapiens Secreted 1 0 2.5 ± 1.0 73 ± 8 -4.9
1.1.63.01. Type 1 signal peptidase, complex with inhibitor 1b12 Escherichia coli Bact. Gram-neg inner 1 0 5.4 ± 1.8 88 ± 7 -5.1
2.1.02.01. Manganese lipoxygenase 5fno Magnaporthe oryzae Eukaryo. plasma 1 0 4.7 ± 0.7 61 ± 2 -9.7
2.1.01.01. Snake phospholipase A2 homolog 2, group II 2q2j Bothrops pirajai Secreted 1 0 1.9 ± 1.2 89 ± 9 -5.6
3.2.05.02. Subterisin 5xm4 Novosphingobium subterraneum Secreted 1 0 4.1 ± 1.6 80 ± 31 -4.5
2.4.05.01. Sterol carrier protein 2 2cx7 Thermus thermophilus Bact. Gram-neg inner 1 0 4.7 ± 1.3 73 ± 13 -6.9
1.3.17.02. Outer membrane protein assembly factor BamA 5or1 Salmonella typhimurium Bact. Gram-neg outer 1 16 24.2 ± 0.8 9 ± 2 -53.7
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase 4fdo Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 4.3 ± 1.1 67 ± 4 -5.3
2.1.01.01. Snake phospholipase A2, acidic, group I 2wq5 Naja naja Secreted 1 0 3.4 ± 0.3 89 ± 6 -6.2
3.2.05.02. Streptomonomicin 2mw3 Streptomonospora alba Secreted 1 0 8.8 ± 3.2 74 ± 1 -10.6
2.2.34.04. Leginsulin 1ju8 Glycine max Secreted 1 0 11.3 ± 1.6 21 ± 17 -8.6
2.2.39.01. Weak tryptophan-containing neurotoxin 2mj0 Naja kaouthia Secreted 1 0 3.6 ± 1.7 57 ± 5 -5.9
1.1.09.01. Zinc-transporting ATPase, ZntA, E2P state 4umv Shigella sonnei Bact. Gram-neg inner 1 8 30.6 ± 1.5 11 ± 2 -56.7
1.1.01.02. Rhodopsin, inactive, structure 2 (with beta-ionone) 3oax Bos taurus Eukaryo. plasma 1 7 30.9 ± 1.4 11 ± 0 -73.6
2.4.50.01. Matrix protein, Indiana virus 1lg7 Vesicular stomatitis virus Viral 1 0 2.7 ± 0.4 82 ± 2 -7.3
3.1.20.01. Alpha-conotoxin Vc1A 2h8s Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.8 59 ± 6 -2.5
1.1.39.03. Folate ECF transporter 4z7f Enterococcus faecalis Bact. Gram-pos plas. 1 6 30.6 ± 1.6 0 ± 1 -53.1
3.1.29.03. Prophenin-1 analogues 2i1e Sus scrofa Secreted 1 0 5.2 ± 1.0 53 ± 7 -7.5
2.2.12.01. Ganglioside GM2 activator, different conformation 1pub Homo sapiens Lysosome 1 0 4.9 ± 0.7 50 ± 8 -7.3
1.3.15.01. Outer membrane protein G (OMPG), open state 1 2iwv Escherichia coli Bact. Gram-neg outer 1 14 25.3 ± 1.4 3 ± 5 -61.3
2.2.41.01. Alpha-defensin corticostatin-related peptide RK-1 1ews Oryctolagus cuniculus Secreted 1 0 4.7 ± 1.1 18 ± 17 -4.4
2.3.06.01. Acetylcholinesterase 4qww Bungarus fasciatus Secreted 1 0 2.0 ± 1.5 36 ± 32 -3.0
1.2.52.01. Cytochrome c-type biogenesis protein CcmE 1sr3 Escherichia coli Bact. Gram-neg inner 1 0 2.8 ± 2.7 59 ± 6 -2.2
2.4.05.01. Sterol carrier protein 2 1pz4 Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.8 ± 5.0 37 ± 49 -1.3
2.2.39.01. Muscarinic m1-toxin1, sequence version 3neq Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 4.0 ± 0.8 65 ± 5 -7.0
2.2.11.01. Protein kinase C beta, C2 domain 1a25 Rattus norvegicus Eukaryo. plasma 1 0 3.1 ± 1.0 44 ± 18 -2.8
2.4.06.01. START domain of collagen type IV alpha-3-binding protein 2e3q Homo sapiens Golgi 1 0 4.3 ± 2.0 41 ± 17 -3.7
1.3.25.01. Gamma-hemolysin, component B 3lkf Staphylococcus aureus Secreted 1 0 1.7 ± 2.5 51 ± 11 -4.5
2.3.13.06. Chloride intracellular channel protein 1 1rk4 Homo sapiens Nuclear outer 1 0 3.0 ± 1.0 40 ± 5 -5.5
1.1.01.01. Bacteriorhodopsin, monomer 1py6 Halobacterium salinarum Archaebac. 1 7 29.6 ± 2.2 24 ± 8 -59.7
1.1.73.01. TrbI protein 2bhv Helicobacter pylori Bact. Gram-neg outer 1 0 3.1 ± 1.3 42 ± 11 -6.4
2.2.20.01. PH domain of GPCR kinase 1 1bak Homo sapiens Eukaryo. plasma 1 0 3.6 ± 0.9 88 ± 2 -6.0
1.2.32.01. Cytochrome P450 2C9, structure 4 5x23 Homo sapiens Endoplasm. reticulum 1 0 6.9 ± 0.8 53 ± 8 -12.1
2.3.06.09. Cutinase 1 1oxm Fusarium solani Secreted 1 0 6.8 ± 1.1 36 ± 15 -9.1
2.4.16.01. Tau-theraphotoxin-Hs1a 2n9z Haplopelma schmidti Secreted 1 0 6.1 ± 1.3 68 ± 10 -5.6
2.1.21.02. Matrix protein p10, myristoylated, structure 3 5lmy Mason-Pfizer monkey virus Viral 1 0 1.6 ± 1.6 60 ± 5 -4.2
2.1.55.01. Secretion factor PAS 2b8i Vibrio vulnificus Secreted 1 0 5.4 ± 1.5 72 ± 7 -5.7
1.1.02.05. Light-harvesting protein B-870, beta chain 1wrg Rhodospirillum rubrum Bact. Gram-neg inner 1 1 27.0 ± 4.7 44 ± 1 -23.9
2.2.06.02. Adipocyte lipid-binding protein 1tow Homo sapiens Eukaryo. plasma 1 0 2.5 ± 1.7 51 ± 18 -4.5
1.2.51.01. Alkaline sphingomyelinase 5udy Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.3 84 ± 10 -4.5
1.1.117.01. DHHC20 palmitoyltransferase, structure 2 6bmm Homo sapiens Golgi 1 4 30.2 ± 4.4 20 ± 2 -50.0
2.1.42.01. Immunity protein for enterocin A (Entl) 2bl7 Enterococcus faecium Secreted 1 0 3.3 ± 1.0 89 ± 3 -4.5
2.3.24.02. Phosphoglycolate phosphatase 1l6r Thermoplasma acidophilum Undefined 1 0 3.6 ± 0.5 86 ± 3 -7.5
1.1.64.01. Sodium/calcium exchanger, structure 1 3v5u Methanococcus jannaschii Archaebac. 1 10 29.8 ± 0.9 3 ± 0 -78.4
1.3.19.01. Porin OpdQ 3t24 Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.0 ± 1.3 2 ± 0 -56.5
2.2.05.01. Plantacyanin 1f56 Spinacia oleracea Thylakoid 1 0 1.4 ± 1.5 11 ± 15 -2.0
3.2.01.06. Lactoferricin B, peptide 36-60 1lfc Bos taurus Secreted 1 0 4.6 ± 0.5 90 ± 6 -5.3
3.1.18.02. Phenol-soluble modulin alpha-1 5khb Staphylococcus aureus Secreted 1 0 9.4 ± 0.8 71 ± 4 -12.7
2.4.15.01. Protein Nef, N-terminal helix (HIV HV1B1) 1zec Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.6 ± 4.1 89 ± 2 -6.8
2.2.06.02. Prostaglandin-H2 D-isomerase, ligand-bound 3o22 Homo sapiens Endoplasm. reticulum 1 0 0.7 ± 1.2 78 ± 13 -2.4
3.1.02.13. Regulatory domain of brain carnitine palmitoyltransferase 2m76 Homo sapiens Mitochon. outer 1 0 6.7 ± 1.0 88 ± 16 -6.9
2.1.60.01. Aurelin 2lg4 Aurelia aurita Secreted 1 0 2.0 ± 0.9 50 ± 6 -4.4
2.1.10.01. Glycolipid transfer protein, conformation 2 1swx Homo sapiens Eukaryo. plasma 1 0 4.6 ± 1.0 87 ± 8 -7.1
2.4.07.01. Sorting nexin-5 3hpc Rattus norvegicus Endosome 1 0 0.0 ± 2.1 90 ± 8 -2.4
2.4.12.01. Liver-expressed antimicrobial peptide 2 2l1q Homo sapiens Secreted 1 0 5.3 ± 1.4 56 ± 11 -2.7
2.2.09.02. Diisopropyl-fluorophosphatase 3o4p Loligo vulgaris (Common European squid) Undefined 1 0 4.6 ± 1.3 82 ± 5 -6.6
1.3.06.02. Carbapenem-associated resistance porin CarO3 4fuv Acinetobacter baumannii Bact. Gram-neg outer 1 8 25.0 ± 2.3 3 ± 1 -38.5
3.1.21.02. Decoralin 2n9a Oreumenes decoratus Secreted 1 0 6.7 ± 1.7 86 ± 11 -8.9
1.1.28.03. SecDF secretion protein, structure 2 5xan Deinococcus radiodurans Bact. Gram-neg inner 1 12 29.0 ± 1.6 5 ± 0 -99.8
1.2.39.02. Stromelysin-1 1c3i Homo sapiens Eukaryo. plasma 1 0 3.6 ± 1.7 85 ± 17 -4.4
1.2.32.01. Cytochrome P450 2R1 3czh Homo sapiens Endoplasm. reticulum 1 0 8.3 ± 1.5 48 ± 13 -13.2
2.2.41.03. Big defensin 2rng Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 6.5 ± 2.3 21 ± 4 -7.5
3.1.07.01. Fusion peptide of spike glycoprotein (772-787) 2rum Human SARS coronavirus Endosome 1 0 11.1 ± 1.1 57 ± 13 -10.8
2.4.16.02. Nasonin 2koz Nasonia vitripennis (Parasitic wasp) Secreted 1 0 2.9 ± 0.9 68 ± 7 -4.6
3.1.04.09. Membrane-permeabilizing peptide (654-676) from hemocyanin 2n1c Litopenaeus vannamei (Whiteleg shrimp) Undefined 1 0 6.5 ± 1.3 90 ± 9 -6.3
1.3.02.01. Opacity protein opA60, structure 1 2maf Neisseria gonorrhoeae Bact. Gram-neg outer 1 8 23.8 ± 1.0 20 ± 1 -34.2
2.1.01.01. Snake phospholipase A2, group II (ecarpholin S) 2qhd Echis carinatus Secreted 1 0 8.1 ± 0.6 79 ± 5 -12.5
3.1.31.01. Dermcidin, structure 2 2ndk Homo sapiens Secreted 1 0 3.0 ± 2.0 86 ± 4 -9.6
2.3.06.15. Polyneuridine-aldehyde esterase 2wfm Rauvolfia serpentina (Serpentwood) Endoplasm. reticulum 1 0 2.5 ± 1.7 88 ± 3 -4.6
2.1.01.01. Snake phospholipase A2, group II 1jlt Vipera ammodytes meridionalis Secreted 1 0 2.8 ± 1.0 89 ± 7 -8.7
3.1.15.01. Leucocin A, linear analogue 2ljt Leuconostoc gelidum Secreted 1 0 4.2 ± 2.8 81 ± 1 -6.6
1.1.64.01. Vacuolar calcium ion transporter 4k1c Saccharomyces cerevisiae Vacuole 1 11 29.8 ± 1.0 3 ± 0 -87.5
2.4.16.04. Defensin-like protein 1brz Pentadiplandra brazzeana Secreted 1 0 1.2 ± 1.2 83 ± 10 -3.6
3.3.03.01. Dodecamer of norleucine 1r9v Designed proteins Undefined 1 0 31.2 ± 6.2 5 ± 16 -16.3
2.2.05.01. Amicyanin 1sfd Paracoccus denitrificans Bact. Gram-neg inner 1 0 3.5 ± 0.8 49 ± 10 -4.0
1.3.17.02. BamABCDE complex, structure 1 5ayw Escherichia coli Bact. Gram-neg outer 1 16 22.8 ± 1.2 7 ± 0 -57.5
1.1.01.02. Opioid mu receptor, active state 5c1m Mus musculus Eukaryo. plasma 1 7 34.4 ± 2.9 9 ± 0 -83.2
1.2.18.01. Putative sortase 2wts Streptococcus pneumoniae Bact. Gram-pos plas. 1 0 5.1 ± 1.0 20 ± 3 -4.6
1.2.38.02. Lysozyme 3hde Enterobacteria phage p21 Secreted 1 0 1.8 ± 1.4 55 ± 10 -4.7
2.2.34.06. Peptide jS3 5wxe Jasminum sambac Secreted 1 0 4.4 ± 1.2 48 ± 12 -6.0
1.1.09.01. Calcium ATPase, E2-Pi state, conformation 4 3b9r Oryctolagus cuniculus Endoplasm. reticulum 1 10 26.8 ± 0.0 25 ± 0 -44.1
2.2.02.01. Exfoliative toxin B 1qtf Staphylococcus aureus Secreted 1 0 2.8 ± 1.9 81 ± 11 -5.8
3.2.05.02. Xanthomonin I 4nag Xanthomonas gardneri Secreted 1 0 8.7 ± 2.4 81 ± 11 -5.0
1.1.33.01. Sodium bile acid symporter, outward-open conformation 1 4n7x Yersinia frederiksenii Bact. Gram-neg inner 1 10 28.6 ± 1.0 12 ± 0 -79.7
2.4.06.01. StAR-related lipid transfer protein 5 2r55 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 47 ± 19 -4.8
2.2.11.01. C2A domain of synaptotagmin-5 5h4y Homo sapiens Vesicle 1 0 2.3 ± 2.3 29 ± 11 -4.5
2.2.34.01. Conotoxin mr3e 2efz Conus marmoreus Secreted 1 0 1.0 ± 1.3 83 ± 25 -3.2
2.3.06.01. Acetylcholinesterase 1qon Drosophila melanogaster Eukaryo. plasma 1 0 5.5 ± 1.6 4 ± 13 -5.0
1.1.01.04. Smoothened 6d32 Xenopus laevis Eukaryo. plasma 1 7 31.8 ± 1.4 12 ± 1 -63.0
2.2.34.02. Delta-amaurobitoxin-Pl1a 1v90 Pireneitega luctuosa (Tangled nest spider) Secreted 1 0 2.9 ± 0.7 26 ± 14 -4.0
1.1.30.01. Membrane protein insertase YidC 2 3wo7 Bacillus halodurans Bact. Gram-pos plas. 1 5 29.0 ± 1.3 12 ± 0 -58.2
2.3.06.09. Cutinase 1 3gbs Aspergillus oryzae Secreted 1 0 11.2 ± 0.5 55 ± 5 -12.6
3.2.05.02. Benenodin-1, state 1 5tj1 Asticcacaulis benevestitus Secreted 1 0 6.0 ± 2.6 78 ± 5 -7.6
1.1.10.04. P-glycoprotein, inward-facing conformation 1b 4lsg Mus musculus Eukaryo. plasma 1 12 31.0 ± 8.0 2 ± 0 -85.3
1.1.79.01. P7 protein (747-809), structure 2 2mts Hepatitis C virus Endoplasm. reticulum 1 2 28.6 ± 2.1 8 ± 2 -26.1
2.4.16.02. Defensin ARD1 1ozz Archaeoprepona demophon Secreted 1 0 4.9 ± 1.7 31 ± 17 -7.1
3.1.29.01. Fowlicidin-2 2gdl Gallus gallus Secreted 1 0 3.1 ± 0.5 85 ± 4 -8.9
2.3.14.01. Retinaldehyde-binding protein 1, closed state 3hx3 Homo sapiens Eukaryo. plasma 1 0 1.2 ± 2.9 77 ± 32 -4.8
3.1.07.03. Hemagglutinin, fusion peptide 346-365, H1 subtype 2kxa Influenza virus Viral 1 0 10.3 ± 1.9 84 ± 13 -14.5
3.1.11.01. Peptide YY 2dez Homo sapiens Secreted 1 0 4.0 ± 0.2 84 ± 2 -5.9
2.1.18.01. Annexin V 1hvf Homo sapiens Eukaryo. plasma 1 0 2.3 ± 1.5 79 ± 10 -5.4
2.1.01.01. Phospholipase A2 2not Notechis scutatus scutatus (Mainland tiger snake) Secreted 1 0 2.6 ± 1.5 73 ± 8 -3.9
1.2.48.01. Lysosome-associated membrane glycoprotein 2, monomer 2mof Homo sapiens Lysosome 1 1 30.6 ± 3.5 42 ± 5 -28.0
1.3.20.01. Outer membrane cobalamin transporter BtuB, meso form 2guf Escherichia coli Bact. Gram-neg outer 1 22 23.4 ± 0.9 6 ± 7 -69.3
2.1.02.01. Arachidonate 15-lipoxygenase 4nre Homo sapiens Eukaryo. plasma 1 0 4.5 ± 1.5 83 ± 2 -10.6
2.3.06.01. Bile-salt activated lipase, structure 1 1f6w Homo sapiens Secreted 1 0 1.8 ± 0.5 81 ± 10 -5.1
2.3.06.01. Carboxylic ester hydrolase, closed state 4be4 Ophiostoma piceae Secreted 1 0 6.4 ± 2.3 61 ± 4 -5.7
1.1.26.07. Fumarate transporter 5da0 Deinococcus radiodurans Bact. Gram-neg inner 1 14 26.8 ± 0.7 13 ± 1 -78.2
2.2.20.01. Cytohesin-2 1u27 Mus musculus Eukaryo. plasma 1 0 0.5 ± 2.4 53 ± 9 -2.4
1.1.34.01. Mitochondrial ADP-ATP carrier, conformation 1 4c9g Saccharomyces cerevisiae Mitochon. inner 1 6 31.4 ± 1.5 1 ± 1 -54.6
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 4 4ut9 Dengue virus Viral 1 0 5.5 ± 2.8 31 ± 8 -5.1
2.2.06.02. Fatty acid-binding protein 2flj Locusta migratoria (Migratory locust) Eukaryo. plasma 1 0 1.2 ± 1.5 62 ± 10 -3.6
2.3.19.02. Histo-blood group ABO system transferase 2rj6 Homo sapiens Golgi 1 0 2.1 ± 1.3 77 ± 3 -7.1
2.1.24.01. Saposin D (peptide 405-486) 2rb3 Homo sapiens Secreted 1 0 2.2 ± 1.7 88 ± 10 -3.4
3.1.05.03. Human platelet factor 4 based peptide, 56-70, modified 1djf Designed proteins Undefined 1 0 1.9 ± 1.4 87 ± 8 -4.9
1.2.01.01. Insulin receptor, peptide 938-988 2mfr Homo sapiens Eukaryo. plasma 1 1 29.8 ± 4.8 41 ± 1 -29.2
2.4.06.01. First StARkin domain of Lam2 5yqi Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.9 ± 1.6 30 ± 8 -4.1
3.1.14.01. Neurokinin A 1n6t Gallus gallus Secreted 1 0 6.8 ± 1.2 60 ± 17 -4.9
3.1.11.02. Exendin-4-conotoxin chimera 2naw Designed proteins Secreted 1 0 4.3 ± 1.4 69 ± 8 -2.7
1.2.24.01. Protein Vpu, cytoplasmic domain, in DPC micelles 2k7y Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 4.5 ± 1.4 54 ± 17 -5.4
2.1.14.02. SusD superfamily protein 3myv Bacteroides vulgatus Secreted 1 0 4.0 ± 1.0 64 ± 2 -6.0
1.1.01.02. Beta-2 adrenergic receptor, active state, complex with G-protein 3sn6 Homo sapiens Eukaryo. plasma 1 7 31.0 ± 1.6 8 ± 1 -68.2
1.1.01.02. Proteinase-activated receptor 2 5ndd Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.4 11 ± 2 -71.1
2.4.28.01. Phenazine biosynthesis protein PhzF 1s7j Enterococcus faecalis Undefined 1 0 1.8 ± 0.7 77 ± 2 -4.3
3.1.01.04. Ferredoxin, chloroplastic, transit peptide (1-32) 1fct Chlamydomonas reinhardtii Thylakoid 1 1 21.8 ± 6.7 28 ± 4 -8.4
1.2.39.02. Matrilysin, structure 1 2mze Homo sapiens Secreted 1 0 3.3 ± 0.9 68 ± 2 -8.0
1.2.44.01. Amyloid beta A4 protein (peptide 672-711) 1ba4 Homo sapiens Eukaryo. plasma 1 0 6.0 ± 0.3 85 ± 5 -10.9
3.1.19.01. Paracelsin X 4by8 Trichoderma reesei Secreted 1 0 14.6 ± 5.1 60 ± 4 -14.6
3.1.07.02. Juxtamembrane peptide (684-719) of protein gp41 2kzq Hepatitis C virus Endosome 1 0 4.3 ± 3.3 88 ± 0 -9.9
2.2.34.06. Antimicrobial peptide 1 1dkc Phytolacca americana (American pokeweed) Secreted 1 0 3.5 ± 1.2 84 ± 10 -4.1
3.1.05.03. LAK160-P12 2l9a Designed proteins Undefined 1 0 4.9 ± 3.1 87 ± 1 -6.7
2.4.11.01. Alpha-1-purothionin 2plh Triticum aestivum Secreted 1 0 2.4 ± 2.0 53 ± 17 -4.6
3.1.20.01. O2-contryphan-Vc2 5l34 Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.4 85 ± 8 -4.2
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 2 3mdm Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 1.3 51 ± 8 -5.9
3.1.19.01. Chrysospermin C 1ee7 Apiocrea chrysosperma Secreted 1 0 9.8 ± 2.3 82 ± 12 -12.2
2.2.11.01. Protein kinase C delta 1yrk Homo sapiens Eukaryo. plasma 1 0 2.0 ± 1.6 52 ± 19 -1.8
3.1.07.02. Juxtamembrane peptide (659-671) of protein gp160 1lcx Human immunodeficiency virus type 1 Endosome 1 0 4.6 ± 2.6 83 ± 16 -8.0
2.1.44.01. Bacteriocin glycocin F 2kuy Lactobacillus plantarum Secreted 1 0 5.4 ± 1.2 65 ± 6 -6.2
3.2.05.02. Sphingopyxin I 5jqf Sphingopyxis alaskensis Undefined 1 0 1.7 ± 1.8 40 ± 16 -3.7
1.3.15.02. CymA protein, conformation 2 4d5b Klebsiella oxytoca Bact. Gram-neg outer 1 14 23.4 ± 1.0 3 ± 1 -48.7
1.1.01.02. P2Y purinoceptor 1, conformation 2 4xnw Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.3 5 ± 1 -72.0
2.3.06.19. Thermostable lipase 5h6b Streptomyces sp. Secreted 1 0 4.4 ± 0.8 58 ± 41 -8.2
1.2.07.01. Protein spitz 3ca7 Drosophila melanogaster Endoplasm. reticulum 1 0 3.3 ± 2.8 87 ± 3 -4.3
2.1.01.01. Snake phospholipase A2, group II, VRV-PL-VIIIa 1zwp Daboia russelli pulchella Secreted 1 0 4.9 ± 1.0 76 ± 7 -12.5
3.4.01.01. Contryphan-In 2m6d Conus inscriptus Secreted 1 0 8.2 ± 1.0 57 ± 15 -5.8
1.1.01.02. TM1-TM2 fragment of fungal STE2 receptor 2k9p Saccharomyces cerevisiae Eukaryo. plasma 1 2 29.8 ± 3.1 21 ± 4 -10.5
3.1.15.03. Bacteriocin peptide plantaricin F (PlnF) 2rlw Lactobacillus plantarum Secreted 1 0 8.7 ± 4.4 79 ± 5 -11.7
1.3.20.01. Ferredoxin receptor FusA 4zgv Pectobacterium atrosepticum Bact. Gram-neg outer 1 22 23.6 ± 0.7 7 ± 0 -65.8
1.2.38.01. Monofunctional glycosyltransferase 3vmr Staphylococcus aureus Bact. Gram-pos plas. 1 1 30.8 ± 1.2 25 ± 2 -35.4
2.2.34.02. U5-theraphotoxin-Hs1b 6av8 Haplopelma schmidti Secreted 1 0 4.8 ± 1.8 49 ± 15 -6.2
3.1.07.07. Fusion protein p14, FAST 2lx0 Reptilian orthoreovirus Eukaryo. plasma 1 1 27.4 ± 2.3 17 ± 9 -20.2
1.2.53.01. Squalene synthase, conformation 1 3v66 Homo sapiens Endoplasm. reticulum 1 0 3.1 ± 0.8 83 ± 6 -5.1
2.2.34.11. Kalata B2, segment 71-98 (repeat 1) 1pt4 Oldenlandia affinis Secreted 1 0 4.6 ± 1.2 83 ± 14 -9.2
2.1.60.03. Pseudecin, conformation 2 2epf Pseudechis porphyriacus Secreted 1 0 5.4 ± 1.1 86 ± 1 -4.6
1.3.02.01. Outer membrane protein NspA 1p4t Neisseria meningitidis Bact. Gram-neg outer 1 8 24.9 ± 2.4 22 ± 3 -42.9
1.1.79.01. P7 protein (747-809), structure 1 3zd0 Hepatitis C virus Endoplasm. reticulum 1 2 29.2 ± 4.2 12 ± 5 -15.3
2.2.34.01. Mu-O conotoxin MrVIB 1rmk Conus marmoreus Secreted 1 0 10.1 ± 1.3 62 ± 19 -10.7
3.1.11.01. Neuropeptide Y analogue 1icy Sus scrofa Secreted 1 0 6.4 ± 0.5 69 ± 6 -8.1
2.2.11.01. Synaptotagmin-13 1wfm Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.9 88 ± 15 -4.5
1.2.54.01. Dihydroorotate dehydrogenase 1d3h Homo sapiens Mitochon. inner 1 0 3.4 ± 0.8 55 ± 6 -10.1
3.1.20.01. Alpha-conotoxin PIVA 1p1p Conus purpurascens (Purple cone) Secreted 1 0 2.4 ± 1.0 30 ± 11 -3.8
1.1.01.02. Adenosine receptor A2a, with Galpha-S protein 5g53 Homo sapiens Eukaryo. plasma 1 7 33.6 ± 2.2 16 ± 0 -69.1
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 2 4nc9 Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 4.1 ± 1.1 69 ± 7 -7.9
3.1.01.01. Varv peptide A/Kalata-B1 propeptide 1wn4 Viola odorata Secreted 1 0 6.4 ± 1.1 81 ± 14 -7.2
3.1.21.12. LyeTxI-b toxin 6cl3 Lycosa erythrognatha Secreted 1 0 11.0 ± 2.4 78 ± 6 -11.2
1.3.19.02. Alginate export protein, AlgE, conformation 1 3rbh Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.4 ± 1.2 4 ± 0 -72.0
1.1.95.02. Ceramide fatty acid hydroxylase SCS7 4zr1 Saccharomyces cerevisiae Endoplasm. reticulum 1 4 28.2 ± 1.6 34 ± 0 -50.6
2.2.39.01. Cardiotoxin II (cytotoxin II) 1ffj Naja naja oxiana Secreted 1 0 7.9 ± 0.8 56 ± 5 -13.7
2.3.06.01. Neuroligin-2 3bl8 Mus musculus Eukaryo. plasma 1 0 1.7 ± 1.6 32 ± 5 -4.1
2.3.13.04. Phospholipid hydroperoxide glutathione peroxidase 5l71 Mus musculus Mitochon. inner 1 0 7.1 ± 1.8 83 ± 14 -5.1
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, mutant 2 2m5f Zaire ebolavirus Viral 1 0 5.7 ± 1.7 29 ± 30 -5.2
3.2.06.01. Paralytic peptide 2 1v28 Manduca sexta Secreted 1 0 2.9 ± 1.4 90 ± 16 -4.9
1.1.47.01. Sensor protein kdpD 2ksf Escherichia coli Bact. Gram-neg inner 1 4 26.2 ± 4.0 45 ± 1 -27.9
2.1.10.01. Glycolipid transfer protein, structure 2 1wbe Bos taurus Eukaryo. plasma 1 0 1.1 ± 2.4 89 ± 8 -9.4
2.2.12.01. Mite group 2 allergen Der f 2 1xwv Dermatophagoides farinae (American house dust mite) Secreted 1 0 1.2 ± 1.4 64 ± 10 -3.1
1.3.20.01. Outer membrane receptor FauA 3efm Bordetella pertussis Bact. Gram-neg outer 1 22 24.7 ± 0.6 11 ± 0 -77.5
2.1.10.01. Ceramide-1-phosphate transfer protein 4kbr Mus musculus Eukaryo. plasma 1 0 3.5 ± 1.5 77 ± 10 -6.9
1.2.32.01. Cytochrome P450 3A4, conformation 3 5te8 Homo sapiens Endoplasm. reticulum 1 0 4.4 ± 1.6 62 ± 5 -13.6
2.3.06.06. Type-B carboxylesterase/lipase 1cle Candida cylindracea Secreted 1 0 10.2 ± 0.0 83 ± 0 -24.7
2.3.01.06. Glycosyl hydrolase PslG 5bxa Pseudomonas aeruginosa Secreted 1 0 6.0 ± 1.2 72 ± 9 -6.9
1.2.43.01. Envelope glycoprotein, Zika virus, structure 4 5lbv Zika virus Viral 1 0 5.7 ± 2.9 31 ± 6 -5.2
2.2.07.03. Streptavidin 1mm9 Streptomyces avidinii Secreted 1 0 4.2 ± 1.6 56 ± 3 -8.4
2.2.20.01. Triple functional domain protein 1nty Homo sapiens Eukaryo. plasma 1 0 3.2 ± 2.0 59 ± 16 -3.9
1.1.12.10. Voltage-gated sodium channel NavPaS 5x0m Periplaneta americana Eukaryo. plasma 1 24 29.4 ± 0.8 7 ± 0 -208.5
2.1.41.01. Phosphatidylinositol 4-kinase type 2-alpha, structure 2 4pla Homo sapiens Golgi 1 0 1.0 ± 1.7 49 ± 3 -2.8
2.4.16.01. Alpha-toxin CsE5 1nra Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.3 ± 1.2 89 ± 22 -4.3
3.1.29.01. LL-37-derived peptide 2l5m Designed proteins Undefined 1 0 6.1 ± 1.0 89 ± 7 -9.7
1.3.19.01. Outer membrane porin OpdL 2y0h Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.0 ± 1.0 3 ± 0 -55.7
3.1.07.06. NS2 protease, segment 845-869 of polyprotein 2mkb Hepatitis GB virus Eukaryo. plasma 1 1 23.2 ± 3.5 30 ± 9 -15.7
3.1.19.01. Trichotoxin a50e 1m24 Trichoderma viride Secreted 1 0 10.4 ± 1.8 75 ± 32 -14.3
2.2.34.06. Peptide jS1 2n5q Jasminum sambac Secreted 1 0 3.8 ± 1.2 71 ± 15 -6.1
1.2.42.01. UDP-2,3-diacylglucosamine hydrolase, lpxH 5k8k Haemophilus influenzae Bact. Gram-neg inner 1 0 9.3 ± 1.8 13 ± 7 -8.7
2.1.41.01. Phosphatidylinositol 3-kinase catalytic subunit type 3 3ls8 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 75 ± 9 -4.7
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 1 2agv Oryctolagus cuniculus Endoplasm. reticulum 1 10 29.7 ± 2.2 20 ± 2 -61.5
1.3.22.01. VDAC-1 channel, structure 1 2jk4 Homo sapiens Mitochon. outer 1 19 23.4 ± 2.3 0 ± 1 -40.0
2.3.16.09. GTP-binding protein YjiA 1nij Escherichia coli Bact. Gram-neg inner 1 0 3.4 ± 0.1 41 ± 1 -6.7
2.4.05.01. Sterol carrier protein 2 1c44 Oryctolagus cuniculus Eukaryo. plasma 1 0 3.7 ± 1.2 74 ± 17 -4.8
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens Endosome 1 0 2.4 ± 1.6 88 ± 12 -4.6
3.1.29.01. Cathelin-related peptide SC5 (SMAP-29) 1fry Ovis aries Secreted 1 0 1.1 ± 0.8 18 ± 9 -3.5
2.3.22.02. NrdI protein 2x2o Bacillus cereus Undefined 1 0 3.6 ± 0.5 77 ± 4 -4.6
3.1.03.06. 12 kDa heat shock protein 4axp Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.5 ± 0.1 74 ± 0 -5.5
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1gym Bacillus cereus Secreted 1 0 4.9 ± 1.0 67 ± 11 -7.2
2.2.39.02. Mambalgin-2 2mfa Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 2.7 ± 2.5 76 ± 5 -6.4
1.2.17.01. Vesicle-associated membrane protein 2 2kog Rattus norvegicus Eukaryo. plasma 1 1 34.8 ± 1.7 27 ± 1 -33.7
2.3.06.02. Antigen 85c, conformation 3 1dqy Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 5.1 ± 1.2 17 ± 3 -6.1
3.1.28.06. Magainin 2, Ala-analogue 4mgp Designed proteins Secreted 1 0 10.0 ± 4.1 79 ± 2 -15.1
2.4.03.01. Tubby protein, ligand-bound 1i7e Mus musculus Eukaryo. plasma 1 0 3.8 ± 1.9 75 ± 13 -4.7
2.4.04.01. Inositol polyphosphate 5-phosphatase OCRL-1 4cmn Homo sapiens Endosome 1 0 6.7 ± 1.6 83 ± 2 -9.2
3.1.28.04. Phylloseptin-3 2jq1 Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 6.4 ± 0.8 74 ± 9 -9.5
3.2.05.02. Microcin J25, redesigned, version 1 2mmt Designed proteins Undefined 1 0 3.0 ± 0.9 90 ± 5 -5.2
1.3.11.01. Diffuse adherence adhesin 4mee Escherichia coli Bact. Gram-neg outer 1 12 26.4 ± 2.4 5 ± 1 -46.6
2.2.11.01. C2 domain of abscisic acid-related protein CAR1 5a50 Arabidopsis thaliana Eukaryo. plasma 1 0 3.4 ± 1.2 79 ± 4 -6.3
2.3.16.02. Translocation ATPase SecA 1tf5 Bacillus subtilis Bact. Gram-pos plas. 1 0 2.5 ± 1.1 64 ± 5 -7.0
2.2.08.01. Osmotin-like protein 1aun Nicotiana tabacum Secreted 1 0 5.8 ± 1.0 85 ± 11 -6.7
3.1.28.09. Pseudin-2, structure 1 2ncy Pseudis paradoxa Secreted 1 0 4.9 ± 3.0 77 ± 5 -5.8
1.1.110.01. Apolipoprotein N-acyl transferase, structure 4 5xhq Escherichia coli Bact. Gram-neg inner 1 8 29.4 ± 1.2 13 ± 2 -70.1
2.4.04.01. Type II inositol-1,4,5-trisphosphate 5-phosphatase 3n9v Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.4 63 ± 6 -6.0
1.2.32.01. Cytochrome P450 2B4, open state 3 3r1b Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.7 ± 0.0 43 ± 5 -9.8
2.1.01.01. Snake phospholipase A2, group I 1poa Naja atra Secreted 1 0 4.8 ± 1.0 89 ± 7 -10.7
1.2.55.01. Neutral ceramidase, structure 2 2zxc Pseudomonas aeruginosa Secreted 1 0 4.6 ± 1.7 71 ± 8 -7.6
1.1.01.02. D2 dopamine receptor 6cm4 Homo sapiens Eukaryo. plasma 1 7 33.0 ± 2.0 8 ± 2 -69.0
1.2.32.01. Plant cytochrome P450 74A (allene oxide synthase) 3dan Parthenium argentatum Vacuole 1 0 7.5 ± 0.4 64 ± 2 -24.1
3.4.09.01. Granin 1lv4 Homo sapiens Secreted 1 0 1.8 ± 0.4 81 ± 3 -6.8
3.2.11.01. Anti-inflammatory peptide 5vav Designed proteins Undefined 1 0 7.7 ± 0.8 63 ± 12 -9.0
1.1.01.02. Lysophosphatidic acid receptor 1 4z34 Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.3 13 ± 1 -74.7
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2w5q Staphylococcus aureus Bact. Gram-pos plas. 1 0 0.4 ± 3.6 82 ± 11 -2.5
2.2.34.02. Huwentoxin-4 1mb6 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 4.4 ± 0.8 70 ± 12 -5.8
2.2.39.01. Cytotoxin-1, in micelles 5nq4 Naja naja oxiana Secreted 1 0 7.9 ± 7.9 55 ± 7 -12.9
1.1.101.01. Oxidoreductase CcdA, outward-facing structure 5vkv Thermus thermophilus Bact. Gram-neg inner 1 6 31.4 ± 1.0 21 ± 0 -85.2
1.1.01.02. Muscarinic acetylcholine receptor M3, structure 1 4daj Rattus norvegicus Eukaryo. plasma 1 7 32.2 ± 1.2 5 ± 0 -75.8
1.2.32.01. Cytochrome P450 1A1 4i8v Homo sapiens Endoplasm. reticulum 1 0 7.1 ± 1.0 64 ± 3 -15.1
2.1.28.01. Heat-stable enterotoxin II 1ehs Escherichia coli Secreted 1 0 1.4 ± 1.1 64 ± 11 -6.0
3.4.12.01. Actinomycin X2 1qfi Streptomyces antibioticus Secreted 1 0 15.2 ± 2.3 35 ± 34 -14.1
2.2.11.01. E3 ubiquitin-protein ligase Itchy homolog 2nq3 Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.9 25 ± 17 -6.7
1.1.01.02. Neuropeptide Y receptor type 1, structure 2 5zbh Homo sapiens Eukaryo. plasma 1 7 31.4 ± 1.6 18 ± 4 -66.7
2.2.11.01. Synaptotagmin-7 2d8k Homo sapiens Vesicle 1 0 2.8 ± 1.3 27 ± 16 -6.6
2.1.29.03. Apolipoprotein C-I, peptide 33-50 1ale Homo sapiens Secreted 1 0 4.9 ± 1.0 72 ± 4 -7.8
1.1.63.01. Type 1 signal peptidase, apo-enzyme 1kn9 Escherichia coli Bact. Gram-neg inner 1 0 3.4 ± 1.4 80 ± 6 -7.8
1.2.03.02. T-cell immunoglobulin and mucin domain-containing protein 4 5f7h Homo sapiens Eukaryo. plasma 1 0 4.7 ± 2.6 65 ± 5 -6.0
2.1.01.01. Snake phospholipase A2, acidic 2, group I 1p7o Micropechis ikaheka Secreted 1 0 2.6 ± 0.5 90 ± 2 -9.4
3.4.12.04. Microcystin-LR 1lcm Microcystis aeruginosa Secreted 1 0 5.5 ± 2.8 76 ± 9 -7.2
1.1.44.01. DsbB - DsbA complex, conformation 1 2hi7 Escherichia coli Bact. Gram-neg inner 1 4 24.3 ± 3.0 30 ± 0 -34.9
1.3.20.01. Siderophore receptor PiuD 5nec Pseudomonas aeruginosa Bact. Gram-neg outer 1 22 24.2 ± 0.8 7 ± 0 -72.9
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase, another loop disordered 4ff6 Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 3.4 ± 1.5 19 ± 6 -6.4
2.1.01.01. Snake phospholipase A2, isoform 3 2osn Bungarus caeruleus Secreted 1 0 2.4 ± 0.6 84 ± 4 -5.8
3.4.08.04. Dynorphin A (1-13) 2n2f Homo sapiens Secreted 1 0 2.5 ± 3.6 78 ± 6 -4.6
2.4.07.01. Sorting nexin-11, conformation 1 4ikb Homo sapiens Eukaryo. plasma 1 0 5.2 ± 2.7 61 ± 8 -6.1
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 6 4coh Trypanosoma cruzi Endoplasm. reticulum 1 0 6.3 ± 1.3 56 ± 6 -7.3
2.2.34.04. Albumin 1 subunit B (Pab1) 1p8b Pisum sativum Secreted 1 0 11.1 ± 0.9 40 ± 13 -8.2
3.2.05.02. Caulonodin 2mlj Caulobacter sp. Secreted 1 0 2.4 ± 1.7 87 ± 15 -5.0
1.1.09.01. Zinc-transporting ATPase, ZntA, E2.PI state 4umw Shigella sonnei Bact. Gram-neg inner 1 8 31.0 ± 1.2 19 ± 2 -65.9
1.1.01.02. Beta-2 adrenergic receptor, active state, complex with antibody 3p0g Homo sapiens Eukaryo. plasma 1 7 30.1 ± 1.4 9 ± 1 -62.9
1.2.33.02. Protoporphyrinogen oxidase 1sez Nicotiana tabacum Mitochon. inner 1 0 2.2 ± 1.0 50 ± 3 -7.0
2.4.50.01. Matrix protein, New Jersey virus 2w2r Vesicular stomatitis virus Viral 1 0 4.1 ± 0.1 57 ± 1 -10.4
3.1.20.01. Alpha-conotoxin ImI 1e75 Conus imperialis (Imperial cone) Secreted 1 0 1.9 ± 0.9 80 ± 15 -3.7
3.1.21.08. Moricin 2jr8 Manduca sexta Secreted 1 0 5.9 ± 1.6 75 ± 3 -11.5
2.2.12.01. Ganglioside GM2 activator, apo-protein 2ag4 Homo sapiens Lysosome 1 0 3.1 ± 1.3 58 ± 12 -5.4
1.3.15.01. Outer membrane protein G (OMPG), closed state 2iww Escherichia coli Bact. Gram-neg outer 1 14 24.7 ± 1.4 6 ± 4 -63.3
1.2.32.01. Cytochrome P450 2B6, conformation 4 4zv8 Homo sapiens Endoplasm. reticulum 1 0 4.5 ± 1.7 57 ± 11 -11.2
2.2.41.02. Antihypertensive protein BDS-1 1bds Anemonia sulcata Secreted 1 0 5.6 ± 0.8 83 ± 9 -9.6
2.3.06.09. Cutinase 4oyy Humicola insolens (Soft-rot fungus) Secreted 1 0 4.9 ± 1.4 46 ± 6 -10.0
1.1.25.07. Nitrate/nitrite exchanger NarK, occluded state 4u4w Escherichia coli Bact. Gram-neg inner 1 12 30.0 ± 1.4 10 ± 1 -91.0
2.2.20.01. PH domain of pleckstrin homology domain-containing family A member 3 2mdx Homo sapiens Eukaryo. plasma 1 0 5.1 ± 1.1 11 ± 19 -4.1
1.2.43.01. Envelope glycoprotein, Dengue virus type 4 3uaj Dengue virus Viral 1 0 5.6 ± 2.6 17 ± 7 -5.4
1.1.25.04. L-fucose-proton symporter fucP 3o7q Escherichia coli Bact. Gram-neg inner 1 12 30.7 ± 1.3 6 ± 0 -85.3
2.2.11.01. Rab3 interacting molecule 2 (RIM2), C2A domain 2bwq Rattus norvegicus Eukaryo. plasma 1 0 1.5 ± 1.6 41 ± 19 -1.8
2.4.06.01. STAR-related lipid transfer protein 11, apoprotein (open state) 2e3m Homo sapiens Golgi 1 0 3.4 ± 1.1 44 ± 12 -6.1
1.3.25.01. Leukocidin F 1pvl Staphylococcus aureus Secreted 1 0 4.0 ± 3.2 47 ± 10 -3.7
2.2.27.01. C1 domain of protein kinase C delta 2yuu Homo sapiens Nuclear outer 1 0 4.0 ± 0.9 77 ± 20 -6.5
1.3.12.01. Outer membrane phospholipase A, monomer 1qd5 Escherichia coli Bact. Gram-neg outer 1 12 24.6 ± 1.2 6 ± 0 -52.6
1.1.12.18. Voltage-gated sensor domain of proton channel Hv1 3wkv Mus musculus Eukaryo. plasma 1 4 32.4 ± 2.1 9 ± 3 -50.4
1.2.32.01. Cytochrome P450 3A4 5veu Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 1.2 63 ± 3 -16.2
2.4.04.01. Sphingomyelinase C 1zwx Listeria ivanovii Secreted 1 0 6.2 ± 0.5 55 ± 1 -10.1
1.2.04.01. Integrin alpha-IIb, cytoplasmic domain 1s4w Homo sapiens Eukaryo. plasma 1 0 2.9 ± 0.3 69 ± 3 -9.1
2.1.21.02. Matrix protein p10, myristoylated, structure 4