PDB ID or protein name

All proteins in OPM (3338 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.1.63.01. Phosphatidylinositol mannoside acyltransferase PatA 5f34 Mycobacterium smegmatis Bact. Gram-pos plas. 0 0 3.9 ± 0.5 58 ± 1 -6.9
2.1.25.03. Enterocin 7A 2m5z Enterococcus faecalis Secreted 0 0 4.4 ± 0.3 57 ± 3 -5.3
2.2.15.01. Gamma-crystallin F 1m8u Bos taurus Secreted 1 0 0.7 ± 1.2 85 ± 4 -4.9
1.2.04.01. Integrin alpha-L, transmembrane helix (1082-1128) 2m3e Homo sapiens Eukaryo. plasma 1 1 29.8 ± 5.6 30 ± 17 -25.9
2.4.16.01. Alpha-insect toxin LqhaIT 2yeo Leiurus quinquestriatus hebraeus Secreted 1 0 3.5 ± 0.8 43 ± 13 -5.9
2.4.07.01. Bud emergence protein 1 2v6v Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.1 ± 1.2 75 ± 6 -5.1
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 3 4j14 Homo sapiens Endoplasm. reticulum 1 0 3.4 ± 1.4 35 ± 19 -4.0
3.1.21.05. Poneratoxin 1g92 Paraponera clavata Secreted 1 0 22.8 ± 8.5 29 ± 7 -12.9
2.2.34.07. Asteropsin E 2m3j Asteropus sp. Secreted 1 0 4.5 ± 1.1 65 ± 7 -3.6
1.1.01.01. Proton-pumping rhodopsin-2 from algae 3am6 Acetabularia acetabulum Eukaryo. plasma 1 7 31.2 ± 1.6 10 ± 1 -65.4
1.1.01.02. 5-hydroxytryptamine receptor 2B, structure 2, with LSD 5tvn Homo sapiens Eukaryo. plasma 1 7 33.0 ± 2.0 18 ± 2 -68.3
1.2.40.01. Mitochondria fission 1 protein, crystal structure 1nzn Homo sapiens Mitochon. outer 1 0 6.1 ± 1.4 72 ± 8 -9.3
2.4.42.01. Cholesteryl ester transfer protein 2obd Homo sapiens Secreted 1 0 7.4 ± 2.9 26 ± 6 -7.0
1.3.20.01. Hemophore receptor HasR, structure 1 3csl Serratia marcescens Bact. Gram-neg outer 1 22 25.4 ± 1.3 4 ± 5 -72.2
2.3.19.02. Histo-blood group ABO system transferase 2rj6 Homo sapiens Golgi 1 0 2.1 ± 1.3 77 ± 3 -7.1
2.4.16.04. Floral defensin-like protein 1 1n4n Petunia hybrida Secreted 1 0 1.8 ± 0.8 6 ± 9 -3.8
3.1.02.02. Potassium voltage-gated channel protein Shaker, peptide 378-397 1ho2 Drosophila melanogaster Eukaryo. plasma 1 0 3.9 ± 1.2 88 ± 16 -7.5
2.1.03.01. Alpha-toxin, different sequence (PHLC2_CLOPE in Uniprot) 1kho Clostridium perfringens Secreted 1 0 3.8 ± 1.0 87 ± 4 -8.2
2.2.39.02. Mambalgin-1 5dz5 Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 6.2 ± 0.1 69 ± 1 -5.6
2.2.10.01. High potential iron protein 1hpi Ectothiorhodospira vacuolata Bact. Gram-neg inner 1 0 2.7 ± 1.0 89 ± 12 -4.4
1.1.34.01. Mitochondrial uncoupling protein 2 2lck Mus musculus Mitochon. inner 1 6 30.0 ± 1.2 12 ± 1 -30.3
2.3.06.02. MPT51/MPB51 antigen 1r88 Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 1.8 ± 1.0 28 ± 26 -3.9
2.1.01.01. MTX-II chain A 4k06 Bothrops brazili Secreted 1 0 5.0 ± 1.3 60 ± 11 -7.1
2.2.07.02. Factor H binding protein 1ys5 Neisseria meningitidis Bact. Gram-neg outer 1 0 3.5 ± 2.6 84 ± 5 -5.6
2.2.20.01. Rho guanine nucleotide exchange factor 9, conformation 1 4mt7 Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 2.6 52 ± 14 -3.9
2.3.12.01. Myotubularin-related protein 2, monomer 1zvr Homo sapiens Endosome 1 0 3.1 ± 0.4 89 ± 8 -5.0
3.2.03.01. Maurocalcine 1s6w Scorpio maurus Secreted 1 0 1.8 ± 1.6 89 ± 21 -2.3
3.1.02.01. Second intracellular loop (118-149) of alpha-2A adrenergic receptor 1hod Homo sapiens Eukaryo. plasma 1 0 3.9 ± 4.1 75 ± 3 -7.2
2.1.08.01. Cytochrome c6 1ls9 Cladophora glomerata Thylakoid 1 0 4.1 ± 1.0 70 ± 14 -2.9
2.2.41.01. Alpha-defensin 4 1zmm Homo sapiens Secreted 1 0 2.2 ± 1.0 76 ± 10 -5.5
2.3.01.10. Galactocerebrosidase 3zr5 Mus musculus Lysosome 1 0 5.2 ± 0.6 87 ± 1 -15.3
3.1.19.01. Zervamicin IIb, transmembrane orientation 1r9u Emericellopsis salmosynnemata Secreted 1 1 23.2 ± 5.4 38 ± 7 -15.0
2.4.51.01. Heme acquisition protein HasA, different strain 3wah Pseudomonas aeruginosa Secreted 1 0 3.4 ± 0.6 14 ± 3 -5.1
1.3.14.01. Fatty Acid Transporter FadL, F3E, open channel 3pgu Escherichia coli Bact. Gram-neg outer 1 14 25.2 ± 1.5 1 ± 1 -51.5
3.1.07.10. Structural peptide 1 of bursal disease virus 2imu Avian infectious bursal disease virus Eukaryo. plasma 1 0 11.6 ± 4.0 76 ± 5 -17.5
3.1.07.01. Fusion peptide (84-101) from E1 envelope glycoprotein 2rsw Chikungunya virus Endosome 1 0 8.3 ± 0.6 57 ± 7 -6.9
2.2.34.02. M-theraphotoxin-Gr1a 1lu8 Grammostola rosea (Chilean rose tarantula) Secreted 1 0 2.8 ± 0.9 69 ± 7 -7.2
2.2.41.02. Toxin APETx1 1wqk Anthopleura elegantissima (Sea anemone) Secreted 1 0 4.0 ± 1.4 32 ± 18 -7.3
3.1.05.08. MSI-594 derived peptide MSI-594-F5A 2l36 Designed proteins Undefined 1 0 6.9 ± 7.0 79 ± 3 -8.3
2.2.11.01. Rabphilin-3A, C2A domain 2chd Rattus norvegicus Eukaryo. plasma 1 0 2.9 ± 1.6 57 ± 19 -2.7
1.2.32.01. Cytochrome P450 2C5 1nr6 Oryctolagus cuniculus Endoplasm. reticulum 1 0 10.6 ± 1.0 54 ± 18 -9.1
2.1.27.01. Cry3Bb1 1ji6 Bacillus thuringiensis Secreted 1 0 3.8 ± 1.6 64 ± 6 -4.2
3.4.08.03. Oxytocin 1xy2 Bos taurus Secreted 1 0 2.1 ± 2.6 86 ± 12 -3.2
3.1.02.01. Third extracellular loop of cholecystokinin A receptor 1hzn Homo sapiens Eukaryo. plasma 1 0 3.4 ± 0.9 81 ± 2 -10.3
2.2.03.01. Plasmepsin-2 1lf2 Plasmodium falciparum Vacuole 1 0 6.2 ± 0.4 76 ± 3 -11.0
2.1.29.03. Apolipoprotein C-I, peptide 61-79 1alf Homo sapiens Secreted 1 0 4.1 ± 0.5 86 ± 3 -9.4
1.1.26.07. Fumarate transporter 5da0 Deinococcus radiodurans Bact. Gram-neg inner 1 14 26.8 ± 0.7 13 ± 1 -78.2
1.2.03.04. Leukocyte immunoglobulin-like receptor subfamily B member 4 3p2t Homo sapiens Eukaryo. plasma 1 0 1.7 ± 0.4 84 ± 5 -5.9
2.1.01.01. Phospholipase A2, group IB 3elo Homo sapiens Secreted 1 0 0.4 ± 1.5 52 ± 16 -3.5
1.1.25.05. Glutathione uptake transporter, structure 1 2xut Shewanella oneidensis Bact. Gram-neg inner 1 14 30.9 ± 1.4 10 ± 0 -102.5
2.2.34.01. Delta conotoxin EVIA 1g1z Conus ermineus Secreted 1 0 6.5 ± 1.9 72 ± 18 -8.7
3.2.03.01. Hepcidin, structure 1 3h0t Homo sapiens Secreted 1 0 4.7 ± 0.6 82 ± 9 -7.0
1.1.01.01. Sensory rhodopsin II, monomer 1h68 Natronomonas pharaonis Archaebac. 1 7 30.3 ± 1.5 15 ± 2 -60.0
1.3.19.02. Alginate export protein, AlgE, conformation 6 5d5d Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.4 ± 1.2 4 ± 1 -67.1
1.1.25.06. Glucose transporter GLUT5, inward-open 4yb9 Bos taurus Eukaryo. plasma 1 12 31.8 ± 1.0 6 ± 0 -89.9
3.1.03.10. Lipid droplet anchoring peptide of CGI-58 5a4h Mus musculus Vesicle 1 0 3.9 ± 1.2 37 ± 7 -7.5
2.2.34.10. Imperatoxin-A 1ie6 Pandinus imperator (Emperor scorpion) Secreted 1 0 2.6 ± 0.8 55 ± 13 -3.1
1.2.44.01. Amyloid beta A4 protein, peptide 686-726 2llm Homo sapiens Eukaryo. plasma 1 1 32.8 ± 2.2 30 ± 0 -30.8
2.2.47.01. Glycoside hydrolase family 9 protein 1wzx Clostridium thermocellum Bact. Gram-pos plas. 1 0 7.4 ± 2.0 77 ± 6 -4.1
2.2.34.11. Tricyclon-A 1yp8 Viola arvensis Secreted 1 0 4.4 ± 1.7 71 ± 19 -4.7
3.2.10.01. PawS derived peptide 4 2lws Designed proteins Undefined 1 0 7.5 ± 1.3 37 ± 13 -5.8
3.1.02.03. Juxtamembrane helix of ATP synthase subunit b 2khk Escherichia coli Bact. Gram-neg inner 1 0 1.9 ± 0.1 85 ± 3 -3.9
2.3.02.01. Phospholipase C-beta isoform 2 2zkm Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.9 38 ± 12 -3.6
3.1.07.06. NS2 protease, segment 836-868 of polyprotein 2kwt Hepatitis C virus Endoplasm. reticulum 1 0 9.5 ± 3.6 81 ± 3 -15.7
2.2.39.01. Cytotoxin 1 ( Cardiotoxin gamma) 1tgx Naja mossambica pallida Secreted 1 0 6.7 ± 1.0 59 ± 12 -10.0
2.1.42.01. Mundticin KS immunity protein 2zrr Enterococcus mundtii Secreted 1 0 1.6 ± 1.5 72 ± 9 -3.2
2.2.09.03. Surface layer protein 1l0q Methanosarcina mazei (Methanosarcina frisia) Archaebac. 1 0 3.1 ± 0.9 81 ± 7 -5.1
2.4.50.01. Matrix protein, Indiana virus 1lg7 Vesicular stomatitis virus Viral 1 0 2.7 ± 0.4 82 ± 2 -7.3
3.1.11.02. Glucagon analog 1bh0 Homo sapiens Secreted 1 0 4.9 ± 4.2 78 ± 2 -6.1
1.3.01.01. Outer membrane protein A (OMPA), disordered loops 1qjp Escherichia coli Bact. Gram-neg outer 1 8 25.4 ± 1.5 11 ± 1 -29.5
1.1.01.03. Corticotropin-releasing factor receptor 1, structure 1 4k5y Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.1 16 ± 3 -71.4
3.1.13.01. Islet amyloid polypeptide, fragment 34-70 2kb8 Homo sapiens Secreted 1 0 3.9 ± 4.2 90 ± 1 -10.2
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 3 2ear Oryctolagus cuniculus Endoplasm. reticulum 1 10 30.0 ± 1.2 19 ± 1 -58.4
2.3.06.06. Triacylglycerol lipase 1lgy Rhizopus niveus Secreted 1 0 1.9 ± 1.8 33 ± 16 -4.8
3.1.29.01. Crotalicidin 2mwt Crotalus durissus terrificus Secreted 1 0 5.2 ± 2.4 86 ± 1 -8.6
1.1.09.01. Calcium ATPase, E1-2Ca state, conformation 4 2c9m Oryctolagus cuniculus Endoplasm. reticulum 1 10 29.8 ± 1.2 27 ± 1 -54.3
2.3.06.08. Pancreatic lipase 1gpl Cavia porcellus Secreted 1 0 5.8 ± 1.0 86 ± 9 -7.8
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 4 4ut9 Dengue virus Viral 1 0 5.5 ± 2.8 31 ± 8 -5.1
2.2.57.01. Levansucrase 1w18 Gluconacetobacter diazotrophicus (Acetobacter diazotrophicus) Secreted 1 0 3.4 ± 1.6 57 ± 3 -7.2
1.3.20.01. Outer membrane cobalamin transporter BtuB, complex with TonB 2gsk Escherichia coli Bact. Gram-neg outer 1 22 23.4 ± 0.7 5 ± 0 -77.5
2.2.14.01. C2 domain of coagulation factor VIII 4mo3 Sus scrofa Eukaryo. plasma 1 0 3.7 ± 0.6 19 ± 4 -9.7
1.1.37.01. Divalent metal cation transporter MntH, structure 2 5m95 Staphylococcus capitis Bact. Gram-pos plas. 1 11 29.8 ± 0.2 9 ± 0 -71.5
2.1.42.01. Putative carnobacteriocin-B2 immunity protein 1tdp Carnobacterium maltaromaticum Secreted 1 0 4.4 ± 0.5 90 ± 9 -4.3
2.2.20.01. Rho GTPase-activating protein 27 3pp2 Homo sapiens Eukaryo. plasma 1 0 2.5 ± 2.2 72 ± 14 -3.4
1.2.53.01. Squalene synthase, conformation 4 3wek Homo sapiens Endoplasm. reticulum 1 0 0.4 ± 2.5 87 ± 15 -3.2
3.1.20.01. alpha-conotoxin auIB 1dg2 Conus aulicus Secreted 1 0 5.1 ± 1.7 89 ± 16 -4.9
3.1.18.02. Phenol-soluble modulin alpha-1 5khb Staphylococcus aureus Secreted 1 0 9.4 ± 0.8 71 ± 4 -12.7
1.1.35.01. Sodium/proton antiporter 1 (NhaA) 1zcd Escherichia coli Bact. Gram-neg inner 1 14 28.4 ± 1.4 2 ± 2 -78.6
2.2.20.01. SET binding factor 1 1v5u Mus musculus Eukaryo. plasma 1 0 4.2 ± 1.5 59 ± 10 -5.3
2.2.06.02. Retinol-binding protein 1 5h9a Homo sapiens Eukaryo. plasma 1 0 3.3 ± 0.9 59 ± 4 -5.7
2.4.06.01. Steroidogenic acute regulatory protein, mitochondrial 3p0l Homo sapiens Mitochon. outer 1 0 3.0 ± 1.3 76 ± 10 -4.7
2.1.60.01. Potassium channel toxin Bgk 1bgk Bunodosoma granulifera Secreted 1 0 1.8 ± 1.7 19 ± 27 -2.9
1.1.10.03. ATP-binding cassette, sub-family B, member 1, mutant 3wmg Cyanidoschyzon merolae Eukaryo. plasma 1 6 36.8 ± 0.3 10 ± 3 -65.5
2.1.41.01. Phosphatidylinositol 4-kinase type 2-alpha, structure 2 4pla Homo sapiens Golgi 1 0 1.0 ± 1.7 49 ± 3 -2.8
2.4.16.06. Mytilin-B 2eem Mytilus edulis (Blue mussel) Secreted 1 0 3.6 ± 1.4 76 ± 8 -3.2
2.3.06.06. Lipase 1, closed (inactive) state 1trh Candida rugosa Secreted 1 0 4.9 ± 1.3 85 ± 7 -7.4
3.1.21.02. Decoralin 2n9a Oreumenes decoratus Secreted 1 0 6.7 ± 1.7 86 ± 11 -8.9
1.1.63.01. Type 1 signal peptidase, complex with lipopeptide inhibitor 1t7d Escherichia coli Bact. Gram-neg inner 1 0 3.9 ± 1.0 65 ± 11 -7.6
2.1.37.01. Erythrocyte membrane protein 1 variant 3c64 Plasmodium falciparum Eukaryo. plasma 1 0 5.3 ± 2.5 52 ± 3 -9.6
2.1.29.03. Apolipoprotein C-I, peptide 1-38 1opp Homo sapiens Secreted 1 0 3.6 ± 0.2 87 ± 2 -10.9
1.3.19.01. Porin OpdF 3szd Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 22.0 ± 1.6 3 ± 0 -60.3
3.1.07.05. Nonstructural protein, membrane-bound domain 1fw5 Semiliki forest virus Endosome 1 0 7.9 ± 1.5 73 ± 17 -10.2
3.1.15.04. Bacteriocin plantaricin K (PlnK) 2keg Lactobacillus plantarum Secreted 1 0 3.3 ± 1.1 83 ± 11 -8.4
2.4.16.05. Micasin 2lr5 Arthroderma otae Secreted 1 0 8.3 ± 0.6 58 ± 6 -7.8
2.3.14.01. Yeast Sec14 Homolog Sfh1 (YKL091C) 3b7n Saccharomyces cerevisiae Nuclear outer 1 0 2.9 ± 1.5 65 ± 18 -5.8
2.1.01.01. Snake phospholipase A2, group I 1ae7 Notechis scutatus scutatus (Mainland tiger snake) Secreted 1 0 4.7 ± 0.6 84 ± 9 -6.2
2.1.62.01. Thuricin 17 2lbz Bacillus cereus Secreted 1 0 3.4 ± 2.6 88 ± 0 -7.7
1.3.10.01. Oligogalacturonate-specific porin KdgM 4fqe Dickeya dadantii Bact. Gram-neg outer 1 12 22.2 ± 1.5 2 ± 1 -42.1
2.3.16.07. Ras-related protein Rab-5C 4kyi Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.4 73 ± 1 -6.0
3.1.07.02. Juxtamembrane peptide (636-662) of protein gp160 2me3 Human immunodeficiency virus type 1 Endosome 1 0 6.1 ± 0.4 81 ± 7 -12.4
2.2.33.01. Hevein 1q9b Hevea brasiliensis (Para rubber tree) Secreted 1 0 1.0 ± 1.0 90 ± 11 -1.8
2.1.01.01. Phospholipase A2 homolog, ammodytin L 3dih Vipera ammodytes ammodytes Secreted 1 0 5.0 ± 0.4 82 ± 5 -14.4
1.1.51.01. Vitamin K epoxide reductase, conformation 1 4nv6 Synechococcus sp. Bact. Gram-neg inner 1 5 29.8 ± 1.8 1 ± 1 -54.2
2.2.22.01. Hydrophobin II 1r2m Hypocrea jecorina Secreted 1 0 4.1 ± 1.0 16 ± 15 -6.6
3.2.05.02. Caulosegnin I 2lx6 Caulobacter segnis Secreted 1 0 2.9 ± 0.8 15 ± 5 -6.0
1.3.17.01. Filamentous hemagglutinin transporter FhaC, structure 2 4ql0 Bordetella pertussis Bact. Gram-neg outer 1 16 23.2 ± 0.9 10 ± 0 -62.7
3.1.04.08. Truncated superoxide dismutase 1 2mp3 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 83 ± 0 -6.3
2.2.34.01. Omega-conotoxin SVIB 1mvj Conus striatus Secreted 1 0 1.1 ± 2.1 20 ± 24 -2.1
2.3.06.05. Carboxylesterase 2h1i Bacillus cereus Bact. Gram-pos plas. 1 0 2.3 ± 1.8 32 ± 31 -3.6
2.1.01.01. Snake phospholipase A2 natratoxin, group I 2osh Naja atra Secreted 1 0 2.6 ± 1.6 83 ± 11 -6.1
2.2.09.01. Kelch-like protein 7 3ii7 Homo sapiens Undefined 1 0 2.6 ± 1.8 90 ± 16 -6.5
1.2.12.01. Fimbrial protein, monomer 1oqw Pseudomonas aeruginosa Bact. Gram-neg inner 1 1 29.8 ± 3.0 31 ± 8 -28.9
2.2.11.01. Synaptotagmin-1, C2A domain (Calcium free) 3f00 Homo sapiens Eukaryo. plasma 1 0 1.4 ± 1.5 29 ± 18 -3.3
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3ld6 Homo sapiens Endoplasm. reticulum 1 0 8.9 ± 0.6 57 ± 2 -16.8
2.2.34.02. Voltage sensor toxin VSTx1 1s6x Grammostola rosea (Chilean rose tarantula) Secreted 1 0 4.4 ± 1.4 79 ± 13 -6.3
3.2.01.07. Protegrin-2 2muh Sus scrofa Secreted 1 0 2.1 ± 3.3 88 ± 2 -3.2
1.1.38.01. H+-driven MATE exporter, outward-open, with nonpeptide inhibitor 3vvp Pyrococcus furiosus Archaebac. 1 12 29.8 ± 1.3 8 ± 0 -79.6
1.3.17.02. BamACDE subcomplex, structure 2 5d0q Escherichia coli Bact. Gram-neg outer 1 16 22.8 ± 1.1 10 ± 0 -44.9
3.1.20.01. Alpha-conotoxin PIA 1zlc Conus purpurascens (Purple cone) Secreted 1 0 2.6 ± 1.3 59 ± 16 -4.3
1.1.56.01. Inner membrane protein YejM, strain LT2 5i5f Salmonella typhimurium Bact. Gram-neg inner 1 0 3.7 ± 2.4 62 ± 11 -4.9
1.2.20.01. Mycobacterial protein Rv1761c 2k3m Mycobacterium tuberculosis Bact. Gram-pos plas. 1 1 23.8 ± 2.1 11 ± 3 -10.2
3.1.29.03. Prophenin-1 2i1d Sus scrofa Secreted 1 0 4.8 ± 1.9 70 ± 35 -5.9
3.4.07.01. VG16KRKP peptide 2mwl Designed proteins Undefined 1 0 4.4 ± 1.3 79 ± 12 -3.6
2.1.08.01. Cytochrome c peroxidase 1nml Marinobacter hydrocarbonoclasticus Bact. Gram-neg inner 1 0 2.2 ± 0.4 83 ± 0 -7.9
1.1.01.02. Dopamine D3 receptor 3pbl Homo sapiens Eukaryo. plasma 1 7 33.0 ± 1.8 8 ± 1 -56.6
2.2.41.01. Beta-defensin 12 1bnb Bos taurus Secreted 1 0 6.0 ± 1.6 88 ± 15 -10.8
3.1.34.01. Conantokin-R1-B 2mzm Conus rolani Secreted 1 0 1.9 ± 0.7 81 ± 8 -2.9
3.1.01.03. N-terminal helix of prion-like protein doppel 1z65 Mus musculus Eukaryo. plasma 1 1 21.0 ± 6.2 8 ± 4 -13.2
1.2.03.05. Cytokine receptor common subunit beta (432-473) 2na8 Homo sapiens Eukaryo. plasma 1 1 34.0 ± 2.8 22 ± 2 -32.9
3.1.07.03. Hemagglutinin, fusion peptide 346-365, H1 subtype 2kxa Influenza virus Viral 1 0 10.3 ± 1.9 84 ± 13 -14.5
2.2.39.01. Muscarinic m1-toxin1 2vlw Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 3.4 ± 0.9 82 ± 9 -4.9
1.1.25.05. Di-or tripeptide:H+ symporter, inward open, structure 1 4aps Streptococcus thermophilus Bact. Gram-pos plas. 1 14 31.8 ± 0.7 13 ± 0 -114.6
1.1.01.02. Muscarinic acetylcholine receptor M2, active 4mqs Homo sapiens Eukaryo. plasma 1 7 32.2 ± 2.1 8 ± 3 -70.0
3.1.28.03. Bombinin-H5 2ap8 Bombina variegata (Yellow-bellied toad) Secreted 1 0 8.6 ± 4.2 77 ± 3 -10.6
2.4.05.01. Sterol carrier protein 2 1pz4 Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.8 ± 5.0 37 ± 49 -1.3
1.2.32.01. Cytochrome P450 2C19 4gqs Homo sapiens Endoplasm. reticulum 1 0 6.4 ± 2.1 71 ± 5 -9.5
3.1.14.01. Kassinin 1myu Kassina senegalensis Secreted 1 0 3.4 ± 1.5 59 ± 16 -4.5
2.2.11.01. Protein kinase C beta, C2 domain 1a25 Rattus norvegicus Eukaryo. plasma 1 0 3.1 ± 1.0 44 ± 18 -2.8
1.1.01.02. C-C chemokine receptor type 2 5t1a Homo sapiens Eukaryo. plasma 1 7 32.6 ± 1.4 3 ± 2 -80.2
1.2.43.01. Envelope glycoprotein, Zika virus, structure 4 5lbv Zika virus Viral 1 0 5.7 ± 2.9 31 ± 6 -5.2
2.2.51.01. 25 kDa protein elicitor 3gnz Pythium aphanidermatum Secreted 1 0 5.7 ± 2.5 77 ± 13 -5.1
1.3.11.01. Serine protease EspP, post-cleavage structure 2qom Escherichia coli Bact. Gram-neg outer 1 12 25.1 ± 1.6 6 ± 7 -55.9
2.2.27.01. Rac GTPase-activating protein 1 4b6d Homo sapiens Eukaryo. plasma 1 0 3.5 ± 0.9 55 ± 4 -5.9
2.4.06.01. STAR-related lipid transfer protein 11, apoprotein (open state) 2e3m Homo sapiens Golgi 1 0 3.4 ± 1.1 44 ± 12 -6.1
2.2.41.01. Oral alpha defensin 1 2k1i Macaca mulatta Secreted 1 0 0.9 ± 3.2 70 ± 15 -2.2
1.2.33.02. Protoporphyrinogen oxidase 2ivd Myxococcus xanthus Bact. Gram-neg inner 1 0 3.7 ± 0.2 29 ± 2 -8.0
1.2.32.01. Cytochrome P450 21-hydroxylase, 21A2 4y8w Homo sapiens Endoplasm. reticulum 1 0 7.2 ± 0.7 59 ± 4 -13.4
3.2.09.02. Gramicidin S 1tk2 Bacillus brevis Secreted 1 0 8.5 ± 1.7 86 ± 21 -8.6
1.2.39.02. Matrilysin, structure 1 2mze Homo sapiens Secreted 1 0 3.3 ± 0.9 68 ± 2 -8.0
2.1.05.02. Farnesyl diphosphate synthase (Geranyltranstransferase) 1rqj Escherichia coli Bact. Gram-neg inner 1 0 3.3 ± 0.7 87 ± 3 -7.7
2.2.06.02. Adipocyte lipid-binding protein 1tow Homo sapiens Eukaryo. plasma 1 0 2.5 ± 1.7 51 ± 18 -4.5
2.2.02.01. Mitochondrial serine protease HtrA2 1lcy Homo sapiens Mitochon. inner 1 0 7.4 ± 1.8 67 ± 14 -5.1
1.2.22.01. Bcl-2-like protein 2 1o0l Homo sapiens Mitochon. outer 1 0 1.7 ± 2.3 86 ± 14 -3.7
2.3.06.07. Lipase 46 kDa form 2hih Staphylococcus hyicus Secreted 1 0 4.6 ± 0.3 83 ± 1 -16.0
1.3.21.01. Outer membrane usher protein FimD, complex with FimC-FimH 3rfz Escherichia coli Bact. Gram-neg outer 1 24 23.8 ± 0.8 5 ± 0 -65.1
1.1.01.05. Metabotropic glutamate receptor 5 4oo9 Homo sapiens Eukaryo. plasma 1 7 32.4 ± 1.2 2 ± 1 -66.3
2.1.14.01. Peroxisomal targeting signal 1 receptor 1fch Homo sapiens Peroxisome 1 0 6.9 ± 1.2 54 ± 3 -6.7
2.4.16.02. Termicin 1mm0 Pseudacanthotermes spiniger Secreted 1 0 4.2 ± 0.5 81 ± 3 -3.3
2.4.15.01. Protein Nef, N-terminal helix (HIV HV1B1) 1zec Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.6 ± 4.1 89 ± 2 -6.8
1.1.70.01. CAAX prenyl protease 1 homolog, structure 1 5syt Homo sapiens Endoplasm. reticulum 1 7 31.4 ± 1.4 15 ± 0 -79.9
2.2.39.01. alpha-Cobratoxin 1ctx Naja kaouthia Secreted 1 0 2.8 ± 1.7 29 ± 18 -4.6
2.2.12.01. Ganglioside GM2 activator 2agc Mus musculus Lysosome 1 0 3.2 ± 1.0 54 ± 12 -5.3
2.1.10.01. Glycolipid transfer protein, conformation 2 1swx Homo sapiens Eukaryo. plasma 1 0 4.6 ± 1.0 87 ± 8 -7.1
1.1.67.01. Transmembrane protein 14C 2los Homo sapiens Mitochon. inner 1 3 26.8 ± 0.4 0 ± 2 -18.5
1.2.44.01. Amyloid beta A4 protein (peptide 672-699) 1amb Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 87 ± 0 -3.2
3.1.07.01. Fusion peptide (510-532) of protein gp41 2pjv Human immunodeficiency virus type 1 Endosome 1 0 8.7 ± 3.8 64 ± 4 -10.9
2.2.33.01. Antimicrobial Peptide AMP-1.1a 2kus Stellaria media Secreted 1 0 1.5 ± 0.9 18 ± 27 -2.7
1.1.09.01. Zinc-transporting ATPase, ZntA, E2.PI state 4umw Shigella sonnei Bact. Gram-neg inner 1 8 31.0 ± 1.2 19 ± 2 -65.9
1.2.32.01. Cytochrome P450 120a1 2ve4 Synechocystis sp. Thylakoid 1 0 6.3 ± 0.9 47 ± 8 -8.6
2.2.22.01. Hydrophobin I 2gvm Hypocrea jecorina Secreted 1 0 5.3 ± 1.1 27 ± 18 -8.7
3.1.06.02. Amphipathic alpha-helix of apolipoprotein 2irg Designed proteins Undefined 1 0 6.4 ± 1.7 83 ± 15 -12.1
1.1.09.01. Calcium ATPase, E1P-ADP state 2zbd Oryctolagus cuniculus Endoplasm. reticulum 1 10 31.8 ± 1.4 22 ± 2 -70.6
2.1.01.01. Snake phospholipase A2, group I 1ozy Micropechis ikaheka Secreted 1 0 2.6 ± 1.0 85 ± 5 -9.0
3.2.04.02. Bowman-Birk type proteinase inhibitor peptide 1gm2 Macrotyloma axillare Secreted 1 0 2.0 ± 1.9 59 ± 14 -3.5
2.4.43.01. Cell wall anchor protein of the T6SS system 4b62 Pseudomonas aeruginosa Bact. Gram-neg outer 1 0 2.8 ± 2.5 46 ± 36 -4.6
1.1.01.02. C-X-C chemokine receptor type 4, complex with peptide 4rws Homo sapiens Eukaryo. plasma 1 7 33.8 ± 1.5 9 ± 1 -76.9
2.2.03.01. Phytepsin 1qdm Hordeum vulgare Vacuole 1 0 9.9 ± 1.1 88 ± 10 -10.4
3.1.15.03. Bacteriocin peptide plantaricin E (PlnE) 2jui Lactobacillus plantarum Secreted 1 0 4.3 ± 4.2 79 ± 4 -5.0
1.1.25.07. Nitrate/nitrite exchanger NarK, occluded state 4u4w Escherichia coli Bact. Gram-neg inner 1 12 30.0 ± 1.4 10 ± 1 -91.0
1.2.44.01. Amyloid beta A4 protein (peptide 688-704), in water 2mj1 Homo sapiens Eukaryo. plasma 1 0 9.4 ± 3.4 38 ± 11 -7.4
1.2.29.01. Septation ring formation regulator EzrA 4uy3 Staphylococcus aureus Bact. Gram-pos plas. 1 0 1.2 ± 2.8 44 ± 4 -3.0
2.3.28.01. Aldo-keto reductase family 1 member C1 1qwk Caenorhabditis elegans Undefined 1 0 2.8 ± 1.0 66 ± 3 -6.3
3.1.28.07. Hylin-A1 2n0o Hypsiboas albopunctatus Secreted 1 0 11.4 ± 0.8 62 ± 4 -15.4
2.1.60.03. Pseudechetoxin 2dda Pseudechis australis Secreted 1 0 4.5 ± 2.8 89 ± 7 -4.3
1.3.15.02. CymA protein, conformation 1 4d51 Klebsiella oxytoca Bact. Gram-neg outer 1 14 25.0 ± 1.7 2 ± 1 -44.8
1.1.01.02. Rhodopsin, complex with arrestin 4zwj Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.1 9 ± 1 -78.7
2.2.34.02. Mu-agatoxin-Aa1a 1eit Agelenopsis aperta Secreted 1 0 1.3 ± 1.5 59 ± 10 -3.1
1.1.77.01. Cellulose synthase, structure 4 5ejz Rhodobacter sphaeroides Bact. Gram-neg inner 1 8 29.6 ± 1.1 18 ± 0 -86.9
2.4.20.02. Arylamine N-acetyltransferase 1w5r Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 2.6 ± 0.5 82 ± 6 -6.2
2.3.06.09. Mycobacterial lipase 3aja Mycobacterium smegmatis Secreted 1 0 6.0 ± 1.0 28 ± 10 -6.7
3.1.05.11. ALPS-23 peptide 2m0w Designed proteins Undefined 1 0 5.7 ± 0.5 72 ± 6 -9.4
1.2.13.01. Intrinsic membrane protein PufX 2ita Rhodobacter sphaeroides Bact. Gram-neg inner 1 1 32.2 ± 5.1 33 ± 1 -22.8
2.4.06.01. StAR-related lipid transfer protein 5 2r55 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 47 ± 19 -4.8
1.2.25.01. Phospholamban, monomer 1n7l Oryctolagus cuniculus Endoplasm. reticulum 1 1 29.8 ± 3.6 34 ± 12 -32.3
2.4.16.03. Charybdotoxin 2crd Leiurus quinquestriatus hebraeus Secreted 1 0 1.1 ± 1.5 86 ± 15 -3.2
3.4.08.04. Met-enkephalin 1plw Homo sapiens Secreted 1 0 4.9 ± 0.8 85 ± 17 -3.8
3.1.11.01. Neuropeptide Y 1ron Homo sapiens Secreted 1 0 7.9 ± 1.6 74 ± 10 -8.6
3.2.10.01. PawS derived peptide 10 2nb6 Designed proteins Undefined 1 0 9.9 ± 2.0 48 ± 30 -9.1
1.1.01.02. Rhodopsin, inactive, conformation 2 3oax Bos taurus Eukaryo. plasma 1 7 30.9 ± 1.4 11 ± 0 -73.6
1.2.32.01. Cytochrome P450 2B6, conformation 2 3ua5 Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 1.1 55 ± 3 -12.9
2.3.08.01. Patatin 1oxw Solanum cardiophyllum Secreted 1 0 3.9 ± 2.0 28 ± 11 -6.5
2.3.06.18. Tle1 effector of type VI lipase 4o5p Pseudomonas aeruginosa Secreted 1 0 3.1 ± 2.5 85 ± 8 -5.8
1.1.01.02. Endothelin B receptor, with endothelin 5glh Homo sapiens Eukaryo. plasma 1 7 34.8 ± 1.0 6 ± 1 -81.5
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, mutant 2 2m5f Zaire ebolavirus Viral 1 0 5.7 ± 1.7 29 ± 30 -5.2
1.2.43.01. Envelope glycoprotein, Dengue virus type 4 3uaj Dengue virus Viral 1 0 5.6 ± 2.6 17 ± 7 -5.4
2.2.21.03. Interleukin-36 receptor antagonist protein 1md6 Mus musculus Secreted 1 0 3.8 ± 0.4 40 ± 3 -6.5
1.3.04.03. Lipid A acylase PagP 3gp6 Escherichia coli Bact. Gram-neg outer 1 8 24.7 ± 1.5 40 ± 1 -32.5
1.1.100.01. Voltage-sensor domain of phosphatase, conformation 1 4g80 Ciona intestinalis Eukaryo. plasma 1 4 29.4 ± 1.4 14 ± 1 -44.6
2.4.16.01. Beta-toxin Cn5 2kja Centruroides noxius (Mexican scorpion) Secreted 1 0 4.1 ± 1.1 73 ± 6 -7.0
2.2.20.01. Cytohesin-2 1u27 Mus musculus Eukaryo. plasma 1 0 0.5 ± 2.4 53 ± 9 -2.4
1.2.32.01. Lanosterol 14-alpha demethylase (CYP51), with drug 4wmz Saccharomyces cerevisiae Endoplasm. reticulum 1 1 29.8 ± 0.7 39 ± 0 -36.1
3.1.12.01. Endothelin-1 1edn Homo sapiens Secreted 1 0 4.3 ± 1.2 71 ± 25 -5.4
2.2.34.06. Peptide jS1 2n5q Jasminum sambac Secreted 1 0 3.8 ± 1.2 71 ± 15 -6.1
2.2.06.02. Fatty acid-binding protein 2flj Locusta migratoria (Migratory locust) Eukaryo. plasma 1 0 1.2 ± 1.5 62 ± 10 -3.6
1.1.01.02. Adenosine receptor A2a, with triazole-carboximidamide antagonist 5uig Homo sapiens Eukaryo. plasma 1 7 30.6 ± 1.4 13 ± 4 -62.6
2.1.01.01. Ammodytin L1 isoform 3ux7 Vipera ammodytes meridionalis Secreted 1 0 2.7 ± 0.3 82 ± 1 -13.2
1.3.09.01. Lipid A deacylase LpxR 3fid Salmonella enterica Bact. Gram-neg outer 1 12 25.6 ± 2.0 24 ± 0 -58.6
2.4.16.04. Defensin 2 (PDF1) 2gl1 Vigna radiata (Mung bean) Secreted 1 0 2.8 ± 0.6 6 ± 4 -5.7
1.1.46.01. MerF bacterial mercury uptake transporter, structure 2 2m67 Morganella morganii Bact. Gram-neg inner 1 2 24.2 ± 4.7 30 ± 1 -29.7
1.2.24.01. Protein Vpu, cytoplasmic domain, in DPC micelles 2k7y Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 4.5 ± 1.4 54 ± 17 -5.4
2.1.03.01. Alpha-toxin (PHLC1_CLOPE), closed state (inactive) 1gyg Clostridium perfringens Secreted 1 0 6.1 ± 2.0 75 ± 6 -5.9
2.2.39.02. Mambalgin-2 2mfa Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 2.7 ± 2.5 76 ± 5 -6.4
1.1.01.02. Beta-2 adrenergic receptor, active state, complex with G-protein 3sn6 Homo sapiens Eukaryo. plasma 1 7 31.0 ± 1.6 8 ± 1 -68.2
2.3.18.01. Carnitine O-palmitoyltransferase 2 2h4t Rattus norvegicus Mitochon. inner 1 0 4.0 ± 1.2 67 ± 10 -9.4
3.1.05.03. Peptide YW12 2o0s Designed proteins Bact. Gram-pos cell wall 1 0 3.4 ± 1.3 82 ± 5 -5.5
2.1.01.03. Phospholipase A2 group XIII 4aup Tuber borchii Secreted 1 0 3.7 ± 0.7 63 ± 6 -7.7
1.3.20.01. Enantio-pyochelin receptor FetA 3qlb Pseudomonas fluorescens Bact. Gram-neg outer 1 22 23.4 ± 0.8 7 ± 0 -75.3
2.2.20.01. Rho guanine nucleotide exchange factor 9, conformation 2 4mt6 Rattus norvegicus Eukaryo. plasma 1 0 3.0 ± 1.9 68 ± 4 -5.1
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-bound 1o7k Homo sapiens Endosome 1 0 15.2 ± 1.7 60 ± 15 -18.4
3.2.01.05. Tachyplesin-1 2rtv Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 4.2 ± 0.4 88 ± 3 -6.8
1.2.44.01. Amyloid beta A4 protein (peptide 672-711) 1ba4 Homo sapiens Eukaryo. plasma 1 0 6.0 ± 0.3 85 ± 5 -10.9
2.2.05.01. Plastocyanin 9pcy Phaseolus vulgaris Thylakoid 1 0 1.8 ± 1.6 18 ± 19 -1.9
2.2.41.01. Alpha-defensin 5 1zmp Homo sapiens Secreted 1 0 4.2 ± 1.6 84 ± 14 -2.8
2.4.20.01. Cathepsin F 1m6d Homo sapiens Lysosome 1 0 4.3 ± 0.8 80 ± 3 -11.7
2.3.06.01. Bile-salt activated lipase, structure 2 1jmy Homo sapiens Secreted 1 0 5.0 ± 1.4 85 ± 9 -5.3
2.4.51.01. Heme acquisition protein HasA 4jet Yersinia pestis Secreted 1 0 4.8 ± 0.9 29 ± 2 -7.0
1.3.14.01. Fatty Acid Transporter FadL, delS3, open channel 2r88 Escherichia coli Bact. Gram-neg outer 1 14 24.0 ± 1.4 6 ± 2 -53.8
3.1.02.15. Glutamate receptor ionotropic, NMDA 1, TMH 2 2nr1 Homo sapiens Eukaryo. plasma 1 0 7.0 ± 3.7 84 ± 0 -12.5
3.1.07.02. Juxtamembrane peptide (657-683) of protein gp160 2me1 Human immunodeficiency virus type 1 Endosome 1 0 7.7 ± 3.8 82 ± 1 -15.0
3.4.09.01. Granin, cyclic analogue 1n2y Bos taurus Secreted 1 0 1.9 ± 2.1 71 ± 16 -3.4
1.2.03.02. Cytotoxic T-lymphocyte protein 4 1dqt Mus musculus Eukaryo. plasma 1 0 3.4 ± 1.6 64 ± 4 -5.3
2.2.41.02. Toxin APETx2 1wxn Anthopleura elegantissima (Sea anemone) Secreted 1 0 4.9 ± 1.7 33 ± 18 -5.5
3.1.05.09. Histidine-rich peptide LAH4 2kjn Designed proteins Undefined 1 0 10.5 ± 6.3 89 ± 2 -10.2
2.2.11.01. Protein kinase C delta 1yrk Homo sapiens Eukaryo. plasma 1 0 2.0 ± 1.6 52 ± 19 -1.8
1.2.32.01. Cytochrome P450 2B4, closed state 1 1suo Oryctolagus cuniculus Endoplasm. reticulum 1 0 4.6 ± 1.3 57 ± 4 -14.2
2.1.27.01. Cry2Aa 1i5p Bacillus thuringiensis Secreted 1 0 3.4 ± 1.2 16 ± 12 -7.0
3.4.12.01. Actinomycin D 1a7y Streptomyces antibioticus Secreted 1 0 11.5 ± 0.9 89 ± 11 -12.2
1.2.04.01. Integrin alpha-X, cytoplasmic helix (peptide 1129-1163) 2luv Homo sapiens Eukaryo. plasma 1 0 4.0 ± 0.5 80 ± 7 -5.8
2.1.29.01. Apolipoprotein E 2l7b Homo sapiens Secreted 1 0 2.5 ± 1.0 73 ± 8 -4.9
1.1.26.07. STAS domain of anion permease 3oiz Rhodobacter sphaeroides Bact. Gram-neg inner 1 0 3.9 ± 0.4 18 ± 5 -5.4
2.1.01.01. Snake phospholipase A2 homolog 2, group II 2q2j Bothrops pirajai Secreted 1 0 1.9 ± 1.2 89 ± 9 -5.6
1.1.01.02. TM1-TM2 fragment of fungal STE2 receptor 2k9p Saccharomyces cerevisiae Eukaryo. plasma 1 2 29.8 ± 3.1 21 ± 4 -10.5
2.2.34.01. Omega conotoxin TxVII 1f3k Conus textile Secreted 1 0 2.8 ± 1.4 57 ± 18 -4.5
3.2.06.01. Growth-blocking peptide 2dj9 Mamestra brassicae Secreted 1 0 2.2 ± 0.7 31 ± 4 -6.2
1.1.01.01. Bacteriorhodopsin, monomer 1py6 Halobacterium salinarum Archaebac. 1 7 29.6 ± 2.2 24 ± 8 -59.7
1.3.17.02. BamACDE subcomplex, structure 1 5ekq Escherichia coli Bact. Gram-neg outer 1 16 23.4 ± 0.7 18 ± 0 -61.9
1.1.25.06. Glucose transporter GLUT5, outward-open 4ybq Rattus norvegicus Eukaryo. plasma 1 12 32.4 ± 3.0 5 ± 0 -110.6
2.3.08.02. Cytosolic phospholipase A2 delta, structure 2 5iz5 Homo sapiens Vesicle 1 0 1.0 ± 0.0 77 ± 0 -4.1
2.2.34.02. Toxin GsMTx2 1lup Grammostola rosea (Chilean rose tarantula) Secreted 1 0 3.8 ± 1.1 90 ± 8 -4.8
1.1.26.01. Leucine transporter LeuT, outward-facing, return state, mutant 5jag Aquifex aeolicus Bact. Gram-neg inner 1 12 26.8 ± 1.1 11 ± 0 -80.7
1.2.05.02. Internalin C 1xeu Listeria monocytogenes Bact. Gram-pos plas. 1 0 2.9 ± 1.3 81 ± 0 -4.1
3.1.01.01. Kalata-B3/B6 propeptide 1wn8 Oldenlandia affinis Secreted 1 0 3.6 ± 1.2 81 ± 22 -8.4
3.2.10.01. PawS derived peptide 5 2lwt Designed proteins Undefined 1 0 8.1 ± 2.2 55 ± 21 -5.2
1.1.26.01. Leucine transporter LeuT, inward-facing conformation 3tt3 Aquifex aeolicus Bact. Gram-neg inner 1 12 27.4 ± 1.6 9 ± 0 -89.1
2.3.06.01. Acetylcholinesterase 1qon Drosophila melanogaster Eukaryo. plasma 1 0 5.5 ± 1.6 4 ± 13 -5.0
3.1.07.05. Nonstructural protein 4b, segment 1751-1780 2jxf Hepatitis C virus Endoplasm. reticulum 1 0 5.6 ± 3.6 85 ± 2 -10.6
2.2.35.01. Suilysin 3hvn Streptococcus suis Secreted 1 0 5.6 ± 1.1 5 ± 4 -6.4
1.1.64.01. Sodium/calcium exchanger, structure 1 3v5u Methanococcus jannaschii Archaebac. 1 10 29.8 ± 0.9 3 ± 0 -78.4
2.1.02.01. Arachidonate 15-lipoxygenase 3rde Sus scrofa Eukaryo. plasma 1 0 6.9 ± 0.4 83 ± 1 -8.7
2.4.50.01. Matrix protein, New Jersey virus 2w2r Vesicular stomatitis virus Viral 1 0 4.1 ± 0.1 57 ± 1 -10.4
3.2.06.01. Paralytic peptide 1 1hrl Manduca sexta Secreted 1 0 6.5 ± 0.6 51 ± 6 -6.2
1.3.01.02. Outer membrane protein X (OMPX) 1qj8 Escherichia coli Bact. Gram-neg outer 1 8 23.6 ± 2.8 12 ± 5 -30.7
1.1.01.03. Glucagon receptor, structure 1 4l6r Homo sapiens Eukaryo. plasma 1 7 28.8 ± 1.8 20 ± 0 -46.7
2.2.12.01. Mite group 2 allergen Der p 2 1ktj Dermatophagoides pteronyssinussearch Secreted 1 0 1.4 ± 1.3 65 ± 9 -3.2
2.3.14.01. Retinaldehyde-binding protein 1, closed state 3hx3 Homo sapiens Eukaryo. plasma 1 0 1.2 ± 2.9 77 ± 32 -4.8
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 4 3fps Oryctolagus cuniculus Endoplasm. reticulum 1 10 30.0 ± 0.9 16 ± 0 -53.5
2.3.06.06. Lipase 1, open (active) state 1lpp Candida rugosa Secreted 1 0 10.0 ± 0.4 83 ± 1 -28.0
3.1.35.01. Cn-AMP1 peptide 2n0v Cocos nucifera Secreted 1 0 2.9 ± 1.3 73 ± 18 -2.3
2.1.18.01. Annexin V 1hvf Homo sapiens Eukaryo. plasma 1 0 2.3 ± 1.5 79 ± 10 -5.4
2.3.06.01. Neuroligin-2 3bl8 Mus musculus Eukaryo. plasma 1 0 1.7 ± 1.6 32 ± 5 -4.1
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 3 3ksw Trypanosoma cruzi Endoplasm. reticulum 1 0 8.0 ± 6.7 61 ± 6 -9.1
2.3.06.08. Pancreatic lipase 1bu8 Rattus norvegicus Secreted 1 0 3.5 ± 1.3 87 ± 10 -6.1
3.1.28.04. Esculentin-1A 2n6m Pelophylax esculentus Secreted 1 0 7.9 ± 0.4 67 ± 5 -7.9
2.1.10.01. Glycolipid transfer protein, structure 2 1wbe Bos taurus Eukaryo. plasma 1 0 1.1 ± 2.4 89 ± 8 -9.4
1.1.105.01. CD81 antigen 5tcx Homo sapiens Eukaryo. plasma 1 4 34.2 ± 2.4 1 ± 1 -55.9
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 5 4utc Dengue virus Viral 1 0 6.3 ± 2.4 13 ± 7 -4.2
2.2.34.02. Neurotoxin Hm-3 2mqu Heriaeus melloteei Secreted 1 0 2.4 ± 0.6 75 ± 11 -7.4
1.3.15.01. Outer membrane protein G (OMPG), open state 1 2iwv Escherichia coli Bact. Gram-neg outer 1 14 25.3 ± 1.4 3 ± 5 -61.3
2.1.10.01. Accelerated-cell-death 11 apo-protein 4nt1 Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 2.0 85 ± 7 -5.4
2.1.42.01. Immunity protein for enterocin A (Entl) 2bl7 Enterococcus faecium Secreted 1 0 3.3 ± 1.0 89 ± 3 -4.5
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form 4ors Homo sapiens Endoplasm. reticulum 1 0 2.6 ± 0.8 71 ± 7 -3.7
3.1.26.01. Pleurocidin 1z64 Pseudopleuronectes americanus Secreted 1 0 5.4 ± 1.3 87 ± 18 -12.8
2.2.41.01. Gallinacin-7 5lcs Gallus gallus Secreted 1 0 2.5 ± 1.4 85 ± 5 -5.6
2.2.20.01. Triple functional domain protein 1nty Homo sapiens Eukaryo. plasma 1 0 3.2 ± 2.0 59 ± 16 -3.9
1.2.22.01. Activator of apoptosis harakiri, cytosolic helix 2l58 Homo sapiens Mitochon. outer 1 0 2.4 ± 4.0 88 ± 0 -8.5
2.1.60.01. Potassium channel toxin ShK 1roo Stoichactis helianthus Secreted 1 0 1.2 ± 1.2 46 ± 8 -3.7
1.1.73.01. TrbI protein 2bhv Helicobacter pylori Bact. Gram-neg outer 1 0 3.1 ± 1.3 42 ± 11 -6.4
1.1.01.02. P2Y purinoceptor 12 4pxz Homo sapiens Eukaryo. plasma 1 7 36.0 ± 1.9 4 ± 3 -79.5
2.4.25.01. N-alpha-acetyltransferase 60, structure 1 5hgz Homo sapiens Golgi 1 0 5.7 ± 1.1 41 ± 7 -8.5
2.4.12.01. Liver-expressed antimicrobial peptide 2 2l1q Homo sapiens Secreted 1 0 5.3 ± 1.4 56 ± 11 -2.7
2.1.41.01. Phosphatidylinositol 3-kinase catalytic subunit type 3 3ls8 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 75 ± 9 -4.7
2.3.06.11. Monoglyceride lipase 4zwn Saccharomyces cerevisiae Endoplasm. reticulum 1 0 4.3 ± 1.7 11 ± 17 -7.5
2.1.42.01. Lactococcin-A immunity protein 5lfi Lactococcus lactis Secreted 1 0 2.7 ± 1.4 40 ± 9 -4.8
1.1.63.01. Type 1 signal peptidase, complex with inhibitor 1b12 Escherichia coli Bact. Gram-neg inner 1 0 5.4 ± 1.8 88 ± 7 -5.1
2.4.05.01. Sterol carrier protein 2 1c44 Oryctolagus cuniculus Eukaryo. plasma 1 0 3.7 ± 1.2 74 ± 17 -4.8
2.2.41.03. Big defensin, segment 43-72 2rq2 Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 1 25.6 ± 4.4 18 ± 2 -13.5
2.2.39.01. Muscarinic m1-toxin1, chimeric sequence 3fev Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 5.5 ± 1.5 76 ± 8 -6.3
1.3.19.01. Porin OpdQ 3t24 Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.0 ± 1.3 2 ± 0 -56.5
2.4.07.01. PX domain of sorting nexin-14 4bgj Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 72 ± 22 -4.3
2.2.26.01. RUN and FYVE domain-containing protein 1 2yw8 Homo sapiens Endosome 1 0 0.7 ± 3.4 48 ± 38 -2.8
2.4.16.02. Nasonin 2koz Nasonia vitripennis (Parasitic wasp) Secreted 1 0 2.9 ± 0.9 68 ± 7 -4.6
1.2.17.01. Vesicle-associated membrane protein 2 2kog Rattus norvegicus Eukaryo. plasma 1 1 34.8 ± 1.7 27 ± 1 -33.7
2.3.06.08. Pancreatic lipase-related protein 2 1w52 Equus caballus Secreted 1 0 4.8 ± 0.2 83 ± 0 -12.7
2.4.03.01. Tubby protein, ligand-bound 1i7e Mus musculus Eukaryo. plasma 1 0 3.8 ± 1.9 75 ± 13 -4.7
2.1.01.01. Snake phospholipase A2, group II, RVV-VD 1vip Vipera russelli Secreted 1 0 4.4 ± 0.8 85 ± 11 -9.5
3.1.20.01. Conotoxin pc16a 2ler Conus pictus Secreted 1 0 4.0 ± 1.0 64 ± 7 -4.1
1.3.06.02. Carbapenem-associated resistance porin CarO3 4fuv Acinetobacter baumannii Bact. Gram-neg outer 1 8 25.0 ± 2.3 3 ± 1 -38.5
1.2.03.05. Erythropoietin receptor (236-284) 2mv6 Homo sapiens Eukaryo. plasma 1 1 31.4 ± 3.3 34 ± 6 -36.3
3.1.07.02. Juxtamembrane peptide (671-697) of protein gp160 2me4 Human immunodeficiency virus type 1 Endosome 1 0 7.9 ± 2.9 81 ± 4 -14.0
2.4.16.04. Defensin-like protein 1brz Pentadiplandra brazzeana Secreted 1 0 1.2 ± 1.2 83 ± 10 -3.6
2.1.49.01. cGMP-specific 3',5'-cyclic phosphodiesterase 1rkp Homo sapiens Eukaryo. plasma 1 0 5.0 ± 1.6 61 ± 11 -5.2
1.2.38.02. Lysozyme 3hde Enterobacteria phage p21 Secreted 1 0 1.8 ± 1.4 55 ± 10 -4.7
2.4.29.01. Superantigen-like protein 3r2t Staphylococcus aureus Undefined 1 0 4.2 ± 0.0 79 ± 1 -6.2
1.2.32.01. Cytochrome P450 2D6, conformation 4 4xry Homo sapiens Endoplasm. reticulum 1 0 8.8 ± 3.0 41 ± 2 -15.5
1.2.11.02. Capsid protein G8P, monomer 2xkm Bacteriophage Pf1 Secreted 1 1 29.2 ± 4.6 34 ± 1 -23.0
3.2.05.02. Lassomycin 2mai Lentzea kentuckyensis Secreted 1 0 3.1 ± 1.0 72 ± 9 -4.7
1.3.02.01. Opacity protein opA60, structure 1 2maf Neisseria gonorrhoeae Bact. Gram-neg outer 1 8 23.8 ± 1.0 20 ± 1 -34.2
2.2.34.01. Conotoxin mr3e 2efz Conus marmoreus Secreted 1 0 1.0 ± 1.3 83 ± 25 -3.2
2.1.02.01. 9R-lipoxygenase 5ek8 Synechococcus sp. Bact. Gram-neg inner 1 0 4.0 ± 0.7 78 ± 6 -12.2
1.1.01.02. Sphingosine 1-phosphate receptor 1 3v2y Homo sapiens Eukaryo. plasma 1 7 32.2 ± 1.4 10 ± 0 -65.9
2.3.06.12. Heroin esterase 1lzk Rhodococcus sp. Bact. Gram-pos plas. 1 0 1.5 ± 1.5 69 ± 9 -4.0
2.1.01.01. Snake phospholipase A2, acidic, group I 2wq5 Naja naja Secreted 1 0 3.4 ± 0.3 89 ± 6 -6.2
2.2.11.01. E3 ubiquitin-protein ligase Itchy homolog 2nq3 Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.9 25 ± 17 -6.7
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3g1q Trypanosoma brucei Endoplasm. reticulum 1 0 8.1 ± 1.5 62 ± 12 -10.8
2.2.34.03. Toxin Ado1 1lmr Agriosphodrus dohrni Secreted 1 0 3.1 ± 1.6 60 ± 19 -4.7
2.2.35.01. Intermedilysin - CD59 receptor complex, disulfide-locked mutant 4bik Streptococcus intermedius Secreted 1 0 5.9 ± 3.1 28 ± 43 -6.4
1.3.17.02. BamABCDE complex, structure 1 5ayw Escherichia coli Bact. Gram-neg outer 1 16 22.8 ± 1.2 7 ± 0 -57.5
3.1.20.01. Alpha-conotoxin Vc1A 2h8s Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.8 59 ± 6 -2.5
1.1.56.01. Inner membrane protein YejM, strain K12 5i5h Salmonella typhimurium Bact. Gram-neg inner 1 0 1.1 ± 1.6 65 ± 2 -3.6
3.1.29.03. Prophenin-1 analogues 2i1e Sus scrofa Secreted 1 0 5.2 ± 1.0 53 ± 7 -7.5
3.1.11.02. Glucagon-like peptide-1 receptor agonists 2n08 Designed proteins Undefined 1 0 6.3 ± 1.3 45 ± 10 -5.4
1.1.49.01. ATP-dependent zinc metalloprotease FtsH 1lv7 Escherichia coli Bact. Gram-neg inner 1 0 2.1 ± 1.0 80 ± 11 -4.3
2.2.11.01. Synaptotagmin-13 1wfm Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.9 88 ± 15 -4.5
2.2.54.01. Non-structural protein 5A 3fqm Hepatitis C virus Endoplasm. reticulum 1 0 4.9 ± 1.1 77 ± 7 -7.5
2.2.41.01. Spheniscin-2 (bird defensin) 1ut3 Aptenodytes patagonicus Secreted 1 0 3.6 ± 1.6 44 ± 17 -6.2
2.2.35.01. Pneumolysin, structure 1 4qqq Streptococcus pneumoniae Secreted 1 0 4.6 ± 3.7 27 ± 7 -6.8
2.2.39.01. Muscarinic m1-toxin1, sequence version 3neq Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 4.0 ± 0.8 65 ± 5 -7.0
2.2.14.01. Coagulation factor VIII, light chain 3j2s Homo sapiens Eukaryo. plasma 1 0 4.8 ± 1.0 34 ± 15 -6.1
1.1.25.05. Di-or tripeptide:H+ symporter, inward open, structure 2 4d2d Streptococcus thermophilus Bact. Gram-pos plas. 1 14 31.0 ± 1.1 7 ± 0 -109.9
1.3.25.01. Gamma-hemolysin, component B 3lkf Staphylococcus aureus Secreted 1 0 1.7 ± 2.5 51 ± 11 -4.5
1.1.15.01. Neuronal acetylcholine receptor, alpha-7 2maw Homo sapiens Eukaryo. plasma 1 4 30.0 ± 1.4 14 ± 1 -41.4
1.1.83.01. Bacterial translocator protein, monomer 4rym Bacillus cereus Bact. Gram-pos plas. 1 5 31.4 ± 1.4 3 ± 0 -52.8
2.1.24.01. Saposin D (peptide 405-486) 2rb3 Homo sapiens Secreted 1 0 2.2 ± 1.7 88 ± 10 -3.4
2.2.20.01. PH domain of pleckstrin homology domain-containing family A member 3 2mdx Homo sapiens Eukaryo. plasma 1 0 5.1 ± 1.1 11 ± 19 -4.1
2.2.20.01. PH domain of oxysterol-binding protein homolog 3, fused with lysozyme 4iap Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.5 ± 2.3 81 ± 3 -3.6
3.1.14.01. Eledoisin 1mxq Eledone cirrhosa (Curled octopus) Secreted 1 0 2.9 ± 1.7 59 ± 19 -5.0
3.1.11.02. Exendin-4-conotoxin chimera 2naw Designed proteins Secreted 1 0 4.3 ± 1.4 69 ± 8 -2.7
2.2.11.01. Rab3 interacting molecule 2 (RIM2), C2A domain 2bwq Rattus norvegicus Eukaryo. plasma 1 0 1.5 ± 1.6 41 ± 19 -1.8
1.2.43.01. Envelope glycoprotein, Zika virus, structure 5 5lbs Zika virus Viral 1 0 2.3 ± 2.5 62 ± 5 -4.7
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 1 3mok Pseudomonas aeruginosa Secreted 1 0 4.5 ± 0.7 37 ± 7 -6.7
1.3.20.01. Outer membrane cobalamin transporter BtuB, meso form 2guf Escherichia coli Bact. Gram-neg outer 1 22 23.4 ± 0.9 6 ± 7 -69.3
2.2.27.01. C1 domain of protein kinase C gamma 2e73 Homo sapiens Eukaryo. plasma 1 0 3.5 ± 1.3 53 ± 9 -4.7
2.3.16.06. ADP-ribosylation factor 1 (ARF1) 2k5u Saccharomyces cerevisiae Golgi 1 0 2.9 ± 1.6 24 ± 18 -5.5
1.1.25.07. Nitrite exporter NarU 4iu9 Escherichia coli Bact. Gram-neg inner 1 12 31.0 ± 1.2 4 ± 0 -88.1
1.2.04.01. Integrin alpha-IIb, cytoplasmic domain 1s4w Homo sapiens Eukaryo. plasma 1 0 2.9 ± 0.3 69 ± 3 -9.1
3.4.02.01. Actagardine, structure in acetonitrile solution 1aj1 Actinoplanes liguriae Secreted 1 0 3.0 ± 1.1 90 ± 11 -5.7
1.2.39.02. Matrilysin, structure 2 2mzi Homo sapiens Secreted 1 0 3.5 ± 0.5 71 ± 4 -7.7
2.2.05.01. Amicyanin 1sfd Paracoccus denitrificans Bact. Gram-neg inner 1 0 3.5 ± 0.8 49 ± 10 -4.0
2.2.06.02. Fatty acid-binding protein homolog 1 1o8v Echinococcus granulosus Eukaryo. plasma 1 0 2.9 ± 1.0 48 ± 15 -5.8
1.2.40.01. Mitochondria fission 1 protein 1y8m Saccharomyces cerevisiae Mitochon. outer 1 0 5.2 ± 0.6 88 ± 1 -5.2
2.2.34.11. Kalata-B8 2b38 Oldenlandia affinis Secreted 1 0 5.5 ± 1.0 88 ± 12 -5.6
3.1.02.14. Tumor-associated calcium signal transducer 2, peptide 304-322 2mae Homo sapiens Eukaryo. plasma 1 0 3.7 ± 3.0 82 ± 0 -3.7
2.2.34.06. Antimicrobial peptide 1 1dkc Phytolacca americana (American pokeweed) Secreted 1 0 3.5 ± 1.2 84 ± 10 -4.1
1.1.09.01. Copper efflux ATPase, E2P state 4bbj Legionella pneumophila Bact. Gram-neg inner 1 8 30.2 ± 0.9 16 ± 1 -69.4
2.4.15.01. Protein Nef 1avv Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.0 ± 1.5 75 ± 13 -3.4
1.1.80.01. UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase 5lev Homo sapiens Endoplasm. reticulum 1 10 31.8 ± 1.0 5 ± 0 -93.5
2.3.01.01. Glucosylceramidase 1ogs Homo sapiens Lysosome 1 0 4.2 ± 1.1 89 ± 4 -9.0
2.4.05.01. Sterol carrier protein 2 2cx7 Thermus thermophilus Bact. Gram-neg inner 1 0 4.7 ± 1.3 73 ± 13 -6.9
2.1.10.01. Glycolipid transfer protein, conformation 1 1sx6 Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.1 85 ± 5 -10.1
1.2.16.01. Pulmonary surfactant-associated protein C 1spf Sus scrofa Secreted 1 1 31.7 ± 3.3 21 ± 0 -32.0
1.2.44.01. Amyloid beta A4 protein (peptide 696-706) 1qcm Homo sapiens Eukaryo. plasma 1 0 2.6 ± 1.5 78 ± 17 -2.9
3.1.07.02. Juxtamembrane peptide (662-683) of protein gp41 2pv6 Human immunodeficiency virus type 1 Endosome 1 0 6.7 ± 0.6 82 ± 2 -13.5
2.1.44.01. Bacteriocin glycocin F 2kuy Lactobacillus plantarum Secreted 1 0 5.4 ± 1.2 65 ± 6 -6.2
2.3.10.07. Lipopolysaccharide biosynthesis protein RfaG 2iw1 Escherichia coli Bact. Gram-neg inner 1 0 3.7 ± 3.1 85 ± 8 -6.0
1.2.39.02. Stromelysin-1 1c3i Homo sapiens Eukaryo. plasma 1 0 3.6 ± 1.7 85 ± 17 -4.4
1.1.56.01. Steryl-sulfatase 1p49 Homo sapiens Endoplasm. reticulum 1 2 29.6 ± 1.1 23 ± 0 -34.6
2.1.01.01. Myotoxin II 1xxs Bothrops moojeni Secreted 1 0 4.5 ± 1.2 76 ± 10 -5.3
3.2.04.03. Peptide leucine arginine 2m3n Lithobates pipiens Secreted 1 0 4.7 ± 0.6 83 ± 5 -5.7
2.2.11.01. Synaptotagmin-1, C2B domain (Calcium-bound) 4v11 Homo sapiens Eukaryo. plasma 1 0 1.6 ± 2.3 40 ± 7 -3.2
2.2.03.01. Plasmepsin IV 1qs8 Plasmodium vivax Vacuole 1 0 9.1 ± 1.5 75 ± 5 -8.9
3.1.15.03. Bacteriocin peptide plantaricin F (PlnF) 2rlw Lactobacillus plantarum Secreted 1 0 8.7 ± 4.4 79 ± 5 -11.7
1.1.25.07. Nitrate/nitrite exchanger NarK, inward-open state 4u4t Escherichia coli Bact. Gram-neg inner 1 12 31.2 ± 1.1 5 ± 1 -94.2
2.3.28.01. Aldo-keto reductase family 1 member C21 3fjn Mus musculus Undefined 1 0 2.8 ± 1.0 56 ± 3 -5.2
1.2.32.01. Cytochrome P450 2D6, conformation 1 2f9q Homo sapiens Endoplasm. reticulum 1 0 7.0 ± 1.8 29 ± 10 -12.0
2.2.35.01. Perfringolysin 1pfo Clostridium perfringens Secreted 1 0 4.4 ± 2.0 38 ± 12 -6.7
2.1.60.03. Pseudecin, conformation 1 2ddb Pseudechis porphyriacus Secreted 1 0 4.8 ± 0.7 90 ± 3 -5.4
1.3.15.02. CymA protein, conformation 2 4d5b Klebsiella oxytoca Bact. Gram-neg outer 1 14 23.4 ± 1.0 3 ± 1 -48.7
1.1.01.02. Neurotensin receptor type 1, structure 3 4xes Rattus norvegicus Eukaryo. plasma 1 7 31.8 ± 1.4 5 ± 1 -68.3
2.2.11.01. Perforin-1 3nsj Mus musculus Vesicle 1 0 3.1 ± 1.0 34 ± 11 -3.3
2.2.34.02. Delta-amaurobitoxin-Pl1a 1v90 Pireneitega luctuosa (Tangled nest spider) Secreted 1 0 2.9 ± 0.7 26 ± 14 -4.0
1.1.69.01. HIG1 domain family member 1A 2lom Homo sapiens Eukaryo. plasma 1 2 22.0 ± 5.0 1 ± 1 -27.3
2.3.06.09. Cutinase 1 3gbs Aspergillus oryzae Secreted 1 0 11.2 ± 0.5 55 ± 5 -12.6
2.4.11.01. Crambin, enantiomer 3ue7 Designed proteins Undefined 1 0 3.4 ± 1.7 89 ± 13 -4.6
1.1.02.05. Light-harvesting protein B-870, beta chain 1wrg Rhodospirillum rubrum Bact. Gram-neg inner 1 1 27.0 ± 4.7 44 ± 1 -23.9
2.4.06.01. Acyl-coenzyme A thioesterase 11 3fo5 Homo sapiens Endoplasm. reticulum 1 0 2.3 ± 1.4 57 ± 7 -3.9
2.4.16.03. Toxin I5a 1sis Buthus eupeus Secreted 1 0 3.1 ± 1.4 74 ± 16 -4.4
3.1.21.01. CECD 2mmm Aedes aegypti (Yellowfever mosquito) Secreted 1 1 20.8 ± 0.8 11 ± 3 -12.3
1.3.20.01. Ferredoxin receptor FusA 4zgv Pectobacterium atrosepticum Bact. Gram-neg outer 1 22 23.6 ± 0.7 7 ± 0 -65.8
3.1.11.01. Peptide YY 2dez Homo sapiens Secreted 1 0 4.0 ± 0.2 84 ± 2 -5.9
1.1.30.01. Membrane protein insertase YidC, structure 2 5m5h Escherichia coli Bact. Gram-neg inner 1 5 30.2 ± 2.2 18 ± 1 -41.3
1.1.25.05. Proton-dependent oligopeptide transporter, conformation 1 4ikv Geobacillus kaustophilus Bact. Gram-pos plas. 1 14 30.8 ± 1.5 5 ± 0 -110.9
2.1.01.01. Phospholipase A2 2not Notechis scutatus scutatus (Mainland tiger snake) Secreted 1 0 2.6 ± 1.5 73 ± 8 -3.9
3.2.10.01. PawS derived peptide 9 2nb5 Designed proteins Undefined 1 0 5.6 ± 1.3 79 ± 14 -6.5
1.1.01.02. Beta-2 adrenergic receptor, active state, complex with antibody 3p0g Homo sapiens Eukaryo. plasma 1 7 30.1 ± 1.4 9 ± 1 -62.9
3.1.07.08. Peptide of outer capsid glycoprotein VP7 (266-326) 2lm7 Rotavirus A Endoplasm. reticulum 1 0 10.2 ± 1.5 76 ± 0 -13.6
2.3.06.01. Bile-salt activated lipase, conformation 1 1aql Bos taurus Secreted 1 0 5.7 ± 1.1 78 ± 7 -9.6
2.3.06.01. Carboxylic ester hydrolase, open state 4be9 Ophiostoma piceae Secreted 1 0 8.7 ± 0.4 88 ± 2 -30.9
1.1.01.02. Endothelin B receptor 5gli Homo sapiens Eukaryo. plasma 1 7 33.6 ± 1.4 11 ± 0 -77.6
2.1.18.01. Annexin V 1yii Gallus gallus Eukaryo. plasma 1 0 3.1 ± 0.7 79 ± 7 -5.1
1.2.43.01. Envelope glycoprotein, chimeric 1k4r Dengue virus Viral 1 0 6.6 ± 2.4 21 ± 12 -4.9
2.2.07.03. Streptavidin 1mm9 Streptomyces avidinii Secreted 1 0 4.2 ± 1.6 56 ± 3 -8.4
1.3.19.02. Alginate export protein, AlgE, conformation 1 3rbh Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.4 ± 1.2 4 ± 0 -72.0
1.1.100.01. Voltage-sensor domain of phosphatase, conformation 2 4g7v Ciona intestinalis Eukaryo. plasma 1 4 30.2 ± 1.8 5 ± 0 -49.2
1.1.39.03. ECF transporter, S-component 5d0y Lactobacillus delbrueckii Bact. Gram-pos plas. 1 6 29.8 ± 1.8 2 ± 2 -55.7
2.4.16.01. Alpha-toxin CsE5 1nra Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.3 ± 1.2 89 ± 22 -4.3
2.2.20.01. Oxysterol-binding protein-related protein 8 1v88 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 78 ± 4 -4.6
3.1.19.01. Zervamicin IIb 1ih9 Emericellopsis salmosynnemata Secreted 1 0 11.5 ± 2.0 74 ± 10 -12.3
2.2.34.02. Beta-theraphotoxin-Tp2a 2n9t Thrixopelma pruriens Secreted 1 0 1.7 ± 0.1 60 ± 1 -7.2
2.2.06.02. Retinol-binding protein 2 2rcq Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 55 ± 6 -5.5
2.2.41.01. Gallinacin-2 2lg5 Gallus gallus Secreted 1 0 8.0 ± 1.2 62 ± 6 -8.2
1.3.20.01. Outer membrane receptor FauA 3efm Bordetella pertussis Bact. Gram-neg outer 1 22 24.7 ± 0.6 11 ± 0 -77.5
1.2.39.03. Disintegrin and metalloproteinase domain-containing protein 10 2ao7 Bos taurus Golgi 1 0 3.1 ± 1.4 81 ± 6 -5.7
3.1.29.01. Cathelin-related peptide SC5 (SMAP-29) 1fry Ovis aries Secreted 1 0 1.1 ± 0.8 18 ± 9 -3.5
1.1.25.05. Bacterial proton:oligopeptide symporter, structure 1 4lep Shewanella oneidensis Bact. Gram-neg inner 1 14 29.4 ± 0.6 7 ± 0 -89.1
1.2.24.01. Protein Vpu, cytoplasmic domain, structure in aqueous solution 1vpu Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.4 ± 2.1 64 ± 5 -5.6
2.3.06.01. Bile-salt activated lipase, conformation 3 2bce Bos taurus Secreted 1 0 5.3 ± 0.8 74 ± 6 -7.0
2.2.34.02. Spiderine-1a, 108-165 2n86 Oxyopes takobius (Lynx spider) Secreted 1 0 5.8 ± 3.7 57 ± 6 -5.7
1.1.25.06. Glucose transporter GLUT3/SLC2A3, outward-open 4zwc Homo sapiens Eukaryo. plasma 1 12 33.0 ± 1.3 6 ± 1 -93.2
1.2.54.01. Dihydroorotate dehydrogenase 3i65 Plasmodium falciparum Mitochon. inner 1 0 5.1 ± 1.0 47 ± 6 -13.6
2.3.18.02. Phthiocerol/phthiodiolone dimycocerosyl transferase 1q9j Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 6.7 ± 2.2 25 ± 6 -5.2
3.1.28.03. Maximin-4 2mhw Bombina maxima Secreted 1 0 4.4 ± 1.0 75 ± 3 -6.3
1.3.19.01. Outer membrane porin OpdL 2y0h Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.0 ± 1.0 3 ± 0 -55.7
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens Endosome 1 0 2.4 ± 1.6 88 ± 12 -4.6
3.1.28.04. Phylloseptin-3 2jq1 Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 6.4 ± 0.8 74 ± 9 -9.5
3.1.02.12. Juxtamembrane peptide of epidermal growth factor receptor 1z9i Homo sapiens Eukaryo. plasma 1 0 4.7 ± 1.6 78 ± 5 -7.1
2.2.05.01. Plastocyanin 2plt Chlamydomonas reinhardtii Thylakoid 1 0 1.3 ± 1.5 21 ± 18 -2.0
2.2.41.01. Alpha-defensin 6 1zmq Homo sapiens Secreted 1 0 3.7 ± 1.6 76 ± 18 -3.6
2.2.06.02. Myelin P2 protein 2wut Homo sapiens Eukaryo. plasma 1 0 4.1 ± 0.5 47 ± 7 -3.4
1.1.34.01. Mitochondrial ADP-ATP carrier, with carboxyatractyloside 2c3e Bos taurus Mitochon. inner 1 6 30.0 ± 1.0 4 ± 2 -44.0
2.1.03.01. Alpha-toxin (PHLC1_CLOPE), open state 1ca1 Clostridium perfringens Secreted 1 0 2.9 ± 1.0 89 ± 4 -9.3
2.4.51.01. Heme acquisition protein HasA, apoprotein 4jes Yersinia pestis Secreted 1 0 5.2 ± 0.3 40 ± 2 -9.6
3.1.02.02. Sodium channel protein type 3 subunit alpha, TMH 2 1qg9 Rattus norvegicus Eukaryo. plasma 1 0 6.8 ± 0.4 86 ± 3 -9.0
3.1.07.01. Probable fusion peptide (93-126, 138-160) of protein gp41 2mk3 Human immunodeficiency virus type 1 Endosome 1 2 20.8 ± 0.5 18 ± 1 -13.2
3.4.09.01. Granin 1lv4 Homo sapiens Secreted 1 0 1.8 ± 0.4 81 ± 3 -6.8
3.1.02.16. Peptide 211-263 of YscU protein 2ml9 Yersinia pseudotuberculosis Bact. Gram-neg inner 1 0 2.9 ± 1.8 82 ± 5 -6.6
2.2.34.02. Huwentoxin-4 1mb6 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 4.4 ± 0.8 70 ± 12 -5.8
2.1.24.01. Pore-forming peptide ameobapore A 1of9 Entamoeba histolytica Undefined 1 0 1.5 ± 1.0 13 ± 18 -2.3
3.1.01.03. Major prion protein, segment 1-30 1skh Bos taurus Eukaryo. plasma 1 1 20.8 ± 6.3 9 ± 5 -10.7
1.2.32.01. Cytochrome P450 2C8 1pq2 Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 1.8 65 ± 9 -8.6
3.1.27.01. Pardaxin, different conformation 1xc0 Pardachirus marmoratus Secreted 1 1 20.8 ± 5.4 42 ± 2 -9.6
3.4.12.01. Actinomycin Z3 1a7z Streptomyces antibioticus Secreted 1 0 10.0 ± 1.3 76 ± 24 -9.6
1.3.11.01. Diffuse adherence adhesin 4mee Escherichia coli Bact. Gram-neg outer 1 12 26.4 ± 2.4 5 ± 1 -46.6
1.1.01.02. P2Y purinoceptor 1, conformation 1 4xnv Homo sapiens Eukaryo. plasma 1 7 32.6 ± 1.7 6 ± 1 -70.3
2.1.29.03. Apolipoprotein C-I, peptide 33-50 1ale Homo sapiens Secreted 1 0 4.9 ± 1.0 72 ± 4 -7.8
1.1.26.07. STAS domain of sulfate permease 4dgh Vibrio cholerae Bact. Gram-neg inner 1 0 4.6 ± 0.6 33 ± 2 -6.2
2.1.01.01. Snake phospholipase A2, acidic 2, group I 1p7o Micropechis ikaheka Secreted 1 0 2.6 ± 0.5 90 ± 2 -9.4
1.2.32.01. Cytochrome P450 1A2 2hi4 Homo sapiens Endoplasm. reticulum 1 0 6.9 ± 1.0 66 ± 9 -16.2
2.2.34.01. Delta conotoxin TxVIA 1fu3 Conus textile Secreted 1 0 6.5 ± 1.8 25 ± 18 -8.3
3.2.01.08. Lactoferricin B, peptide 10-19 1y5c Bos taurus Secreted 1 0 2.2 ± 1.2 54 ± 11 -3.4
3.1.20.01. Alpha-conotoxin PIVA 1p1p Conus purpurascens (Purple cone) Secreted 1 0 2.4 ± 1.0 30 ± 11 -3.8
1.1.29.01. YddG transporter 5i20 Starkeya novella Bact. Gram-neg inner 1 10 30.2 ± 1.3 0 ± 0 -78.1
1.1.01.02. Adenosine receptor A2a, inactive state, with annular lipids 4eiy Homo sapiens Eukaryo. plasma 1 7 32.2 ± 1.2 18 ± 0 -70.4
2.3.01.08. Endoglucanase H 2vi0 Clostridium thermocellum Bact. Gram-pos plas. 1 0 1.5 ± 1.3 36 ± 9 -3.8
3.1.01.01. Varv peptide A/Kalata-B1 propeptide 1wn4 Viola odorata Secreted 1 0 6.4 ± 1.1 81 ± 14 -7.2
3.2.10.01. PawS derived peptide 7 2lwu Designed proteins Undefined 1 0 2.0 ± 1.4 81 ± 10 -3.0
2.1.02.01. 8R-Lipoxygenase, complete structure 3dy5 Plexaura homomalla Eukaryo. plasma 1 0 2.3 ± 1.5 88 ± 10 -3.2
3.1.09.01. ICP47 protein, active domain (1-34) 1qlo Human herpesvirus Endoplasm. reticulum 1 0 8.6 ± 0.8 58 ± 8 -10.2
2.2.39.01. Cardiotoxin VI 1ug4 Naja atra Secreted 1 0 6.4 ± 0.9 62 ± 4 -12.2
2.4.50.01. Matrix protein, Indiana virus, complex with mRNA export factor 4owr Vesicular stomatitis virus Viral 1 0 2.1 ± 0.8 65 ± 2 -7.6
3.2.06.01. Paralytic peptide 2 1v28 Manduca sexta Secreted 1 0 2.9 ± 1.4 90 ± 16 -4.9
1.3.02.01. Outer membrane protein NspA 1p4t Neisseria meningitidis Bact. Gram-neg outer 1 8 24.9 ± 2.4 22 ± 3 -42.9
2.2.16.01. Lipoprotein LprG 3mh9 Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 2.5 ± 2.7 47 ± 10 -3.0
2.2.12.01. Mite group 2 allergen Der f 2 1xwv Dermatophagoides farinae (American house dust mite) Secreted 1 0 1.2 ± 1.4 64 ± 10 -3.1
2.3.14.01. Retinaldehyde-binding protein 1, closed state, more complete structure 3hy5 Homo sapiens Eukaryo. plasma 1 0 2.0 ± 3.9 55 ± 17 -4.5
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 5 1kju Oryctolagus cuniculus Endoplasm. reticulum 1 10 33.8 ± 0.2 26 ± 1 -68.6
2.3.06.06. Lipase 2 1gz7 Candida rugosa Secreted 1 0 4.8 ± 1.3 87 ± 10 -8.5
3.1.15.01. Enterocin-HF 2n4k Enterococcus faecium Secreted 1 0 4.8 ± 3.5 82 ± 4 -4.8
1.2.32.01. Cytochrome P450 2B4, closed state 2 2q6n Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.5 ± 0.4 55 ± 2 -13.0
2.3.06.09. Cutinase 1 1oxm Fusarium solani Secreted 1 0 6.8 ± 1.1 36 ± 15 -9.1
2.4.16.01. Tau-theraphotoxin-Hs1a 2n9z Haplopelma schmidti Secreted 1 0 6.1 ± 1.3 68 ± 10 -5.6
1.1.01.02. Cannabinoid receptor 1, structure 2 5u09 Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 9 ± 0 -71.8
2.1.55.01. Secretion factor PAS 2b8i Vibrio vulnificus Secreted 1 0 5.4 ± 1.5 72 ± 7 -5.7
1.3.15.01. Outer membrane protein G (OMPG), closed state 2iww Escherichia coli Bact. Gram-neg outer 1 14 24.7 ± 1.4 6 ± 4 -63.3
2.1.10.01. Accelerated-cell-death 11 protein, complex with lipid 4nti Arabidopsis thaliana Eukaryo. plasma 1 0 5.7 ± 0.5 80 ± 2 -10.7
1.1.37.01. Divalent metal cation transporter MntH 5m87 Eremococcus coleocola Bact. Gram-pos plas. 1 12 30.2 ± 0.6 10 ± 0 -96.6
2.1.42.01. Bacteriocin 2fu2 Streptococcus pyogenes Secreted 1 0 1.6 ± 1.1 77 ± 16 -3.7
1.1.44.01. DsbB - DsbA complex, conformation 4 3e9j Escherichia coli Bact. Gram-neg inner 1 4 26.8 ± 1.5 31 ± 1 -27.1
1.2.03.02. T-cell immunoglobulin and mucin domain-containing protein 4 3bib Mus musculus Eukaryo. plasma 1 0 3.2 ± 1.9 41 ± 7 -4.6
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form, mutant 4os0 Homo sapiens Endoplasm. reticulum 1 0 2.4 ± 1.0 77 ± 4 -3.1
3.2.01.08. Lactoferricin B, peptide 36-60 1lfc Bos taurus Secreted 1 0 4.6 ± 0.5 90 ± 6 -5.3
1.2.42.01. Sphingomyelin phosphodiesterase 5i85 Homo sapiens Secreted 1 0 7.1 ± 1.4 53 ± 2 -9.2
2.2.20.01. Phosphoinositol 3-phosphate binding protein 1 1upr Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.4 62 ± 19 -3.6
2.3.18.01. Carnitine O-palmitoyltransferase 1, liver isoform, N-terminal domain 2le3 Homo sapiens Mitochon. outer 1 0 3.9 ± 3.7 80 ± 3 -9.3
2.1.60.01. Aurelin 2lg4 Aurelia aurita Secreted 1 0 2.0 ± 0.9 50 ± 6 -4.4
1.3.12.01. Outer membrane phospholipase A, monomer 1qd5 Escherichia coli Bact. Gram-neg outer 1 12 24.6 ± 1.2 6 ± 0 -52.6
1.2.25.02. Na,K-ATPase regulatory protein FXYD2 2mkv Homo sapiens Eukaryo. plasma 1 1 30.6 ± 3.0 23 ± 2 -25.9
2.4.25.01. N-alpha-acetyltransferase 60, structure 2 5hh0 Homo sapiens Golgi 1 0 5.2 ± 0.0 46 ± 1 -10.7
2.2.41.04. Antimicrobial peptide LCI 2b9k Bacillus subtilis Secreted 1 0 1.6 ± 2.9 89 ± 19 -4.4
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, delta isoform 2wxf Mus musculus Eukaryo. plasma 1 0 2.3 ± 1.8 89 ± 3 -5.3
1.2.32.01. Lanosterol 14-alpha demethylase 5jlc Candida glabrata Endoplasm. reticulum 1 1 29.8 ± 0.7 25 ± 1 -31.5
2.2.34.12. Poneritoxin, omega-PONTX-Ae1a 2nbc Anochetus emarginatus Secreted 1 0 1.7 ± 1.8 72 ± 12 -2.5
1.1.63.01. Type 1 signal peptidase, apo-enzyme 1kn9 Escherichia coli Bact. Gram-neg inner 1 0 3.4 ± 1.4 80 ± 6 -7.8
1.2.17.02. Synaptobrevin homolog 1 1iou Saccharomyces cerevisiae Eukaryo. plasma 1 0 3.4 ± 1.1 79 ± 12 -6.0
2.3.21.01. Protein-tyrosine phosphatase, mitochondrial 1 3rgq Mus musculus Mitochon. inner 1 0 1.7 ± 0.7 54 ± 7 -4.9
2.2.41.03. Big defensin 2rng Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 6.5 ± 2.3 21 ± 4 -7.5
1.3.20.01. Transferrin-binding protein A, complex with human serotransferrin 3v89 Neisseria meningitidis Bact. Gram-neg outer 1 22 22.8 ± 0.8 3 ± 1 -68.9
1.1.01.02. Opsin, complex with arrestin peptide 4pxf Bos taurus Eukaryo. plasma 1 7 31.6 ± 0.9 8 ± 1 -80.1
2.4.07.01. Sorting nexin-5 3hpc Rattus norvegicus Endosome 1 0 0.0 ± 2.1 90 ± 8 -2.4
3.1.23.01. Meucin-24 2kfe Mesobuthus eupeus Secreted 1 0 4.3 ± 3.5 82 ± 2 -7.5
2.1.01.01. Snake phospholipase A2, group II (ecarpholin S) 2qhd Echis carinatus Secreted 1 0 8.1 ± 0.6 79 ± 5 -12.5
2.4.03.01. Tubby protein, ligand-free 1c8z Mus musculus Eukaryo. plasma 1 0 2.8 ± 0.9 89 ± 13 -5.8
2.1.01.01. Snake phospholipase A2, group II 1jlt Vipera ammodytes meridionalis Secreted 1 0 2.8 ± 1.0 89 ± 7 -8.7
3.1.15.01. Leucocin A, linear analogue 2ljt Leuconostoc gelidum Secreted 1 0 4.2 ± 2.8 81 ± 1 -6.6
1.3.19.02. Alginate export protein, AlgE, conformation 3 4b61 Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 24.0 ± 1.1 5 ± 1 -73.2
3.1.07.01. Fusion peptide (772-787) of spike glycoprotein 2rum Human SARS coronavirus Endosome 1 0 11.1 ± 1.1 57 ± 13 -10.8
2.2.41.05. Crotamine 1z99 Crotalus durissus terrificus Secreted 1 0 3.7 ± 0.8 26 ± 5 -5.6
1.1.01.01. Sodium pumping rhodopsin, NaR, monomer 4xtl Dokdonia eikasta Bact. Gram-neg inner 1 7 29.8 ± 1.9 20 ± 2 -57.4
2.4.04.01. Type II inositol-1,4,5-trisphosphate 5-phosphatase 3n9v Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.4 63 ± 6 -6.0
2.1.03.01. Alpha-toxin (PHLC_CLOP1) 2wxu Clostridium perfringens Secreted 1 0 4.0 ± 0.9 85 ± 5 -7.0
2.1.48.01. Glycerol dehydrogenase 1kq3 Thermotoga maritima Undefined 1 0 2.5 ± 1.8 80 ± 5 -4.3
1.1.47.01. Sensor protein kdpD 2ksf Escherichia coli Bact. Gram-neg inner 1 4 26.2 ± 4.0 45 ± 1 -27.9
2.2.20.03. Radixin 1gc6 Mus musculus Eukaryo. plasma 1 0 15.4 ± 1.8 17 ± 12 -17.9
1.2.39.01. Endoplasmic reticulum aminopeptidase 1, different conformation 2yd0 Homo sapiens Endoplasm. reticulum 1 0 4.1 ± 2.2 59 ± 8 -4.6
2.2.02.01. Exfoliative toxin B 1qtf Staphylococcus aureus Secreted 1 0 2.8 ± 1.9 81 ± 11 -5.8
3.2.05.02. Xanthomonin I 4nag Xanthomonas gardneri Secreted 1 0 8.7 ± 2.4 81 ± 11 -5.0
2.2.34.01. Mu-conotoxin GS 1ag7 Conus geographus (Geography cone) Secreted 1 0 1.9 ± 1.0 68 ± 15 -2.6
1.1.01.02. Muscarinic acetylcholine receptor M3, structure 1 4daj Rattus norvegicus Eukaryo. plasma 1 7 32.2 ± 1.2 5 ± 0 -75.8
2.3.06.12. Carboxylesterase 2hm7 Alicyclobacillus acidocaldarius Bact. Gram-pos plas. 1 0 5.8 ± 1.7 70 ± 5 -7.7
2.1.01.01. Snake phospholipase A2, isoform 3 2osn Bungarus caeruleus Secreted 1 0 2.4 ± 0.6 84 ± 4 -5.8
2.3.27.01. Dihydrofolate reductase 3nzb Pneumocystis carinii Undefined 1 0 3.9 ± 1.9 72 ± 10 -5.9
2.2.11.01. Synaptotagmin-1 C2A-C2B domains 2r83 Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.9 89 ± 10 -3.8
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 1 2wuz Trypanosoma cruzi Endoplasm. reticulum 1 0 4.0 ± 1.1 75 ± 11 -9.9
2.2.34.04. Leginsulin 1ju8 Glycine max Secreted 1 0 11.3 ± 1.6 21 ± 17 -8.6
2.2.39.01. Weak tryptophan-containing neurotoxin 2mj0 Naja kaouthia Secreted 1 0 3.6 ± 1.7 57 ± 5 -5.9
1.3.20.01. Outer membrane receptor PiuA 5fok Pseudomonas aeruginosa Bact. Gram-neg outer 1 22 23.4 ± 1.1 3 ± 1 -65.9
2.1.02.01. Manganese lipoxygenase 5fno Magnaporthe oryzae Eukaryo. plasma 1 0 4.7 ± 0.7 61 ± 2 -9.7
3.1.20.01. Alpha-conotoxin ImI 1e75 Conus imperialis (Imperial cone) Secreted 1 0 1.9 ± 0.9 80 ± 15 -3.7
1.1.01.02. Thrombin (proteinase-activated) receptor 1, PAR1 3vw7 Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.9 1 ± 0 -72.2
3.1.21.08. Moricin 2jr8 Manduca sexta Secreted 1 0 5.9 ± 1.6 75 ± 3 -11.5
3.1.05.13. Cullin3-derived peptides 2myl Designed proteins Undefined 1 0 3.4 ± 1.2 82 ± 21 -4.4
2.3.16.09. GTP-binding protein YjiA 1nij Escherichia coli Bact. Gram-neg inner 1 0 3.4 ± 0.1 41 ± 1 -6.7
2.2.11.01. Synaptotagmin-17 2enp Homo sapiens Eukaryo. plasma 1 0 4.6 ± 1.5 6 ± 14 -4.9
1.2.32.01. Steroid 21-hydroxylase (P450 C21) 3qz1 Bos taurus Endoplasm. reticulum 1 0 5.9 ± 1.6 72 ± 3 -10.4
2.2.41.01. Alpha-defensin corticostatin-related peptide RK-1 1ews Oryctolagus cuniculus Secreted 1 0 4.7 ± 1.1 18 ± 17 -4.4
2.3.06.01. Acetylcholinesterase 4qww Bungarus fasciatus Secreted 1 0 2.0 ± 1.5 36 ± 32 -3.0
1.1.64.01. H+/Ca2+ exchanger 4kpp Archaeoglobus fulgidus Archaebac. 1 12 29.8 ± 1.4 5 ± 0 -92.3
2.2.14.01. C2 domain of coagulation factor V 1czs Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.6 13 ± 15 -6.2
3.1.07.05. Nonstructural protein 4b, segment 1716-1755 2lvg Hepatitis C virus Viral 1 0 6.4 ± 0.7 82 ± 8 -11.4
1.1.26.01. Dopamine transporter, outward-facing conformation 4m48 Drosophila melanogaster Eukaryo. plasma 1 12 30.8 ± 1.6 12 ± 0 -101.0
1.1.26.02. Sodium-hydantoin transporter Mhp1, outward-facing conformation 1 4d1b Mycobacterium liquefaciens Bact. Gram-pos plas. 1 12 29.8 ± 0.9 17 ± 0 -96.4
1.3.25.01. Leukocidin F 1pvl Staphylococcus aureus Secreted 1 0 4.0 ± 3.2 47 ± 10 -3.7
1.1.25.06. D-xylose-proton symporter xylE, conformation 1 4gc0 Escherichia coli Bact. Gram-neg inner 1 12 30.2 ± 0.9 1 ± 0 -90.2
1.1.10.04. P-glycoprotein, inward-facing conformation 1c 4m1m Mus musculus Eukaryo. plasma 1 12 31.2 ± 1.3 2 ± 1 -90.6
2.4.11.01. Beta-hordothionin 1wuw Hordeum vulgare Secreted 1 0 3.6 ± 1.1 55 ± 15 -5.4
2.4.13.01. Oxysterol-binding protein homolog 3 4ic4 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 4.3 ± 0.9 86 ± 29 -5.9
3.1.14.01. Neurokinin A 1n6t Gallus gallus Secreted 1 0 6.8 ± 1.2 60 ± 17 -4.9
2.4.16.04. Defensin-like protein 2 2n2r Raphanus sativus Secreted 1 0 2.5 ± 1.7 31 ± 24 -4.2
1.1.01.02. Neurotensin receptor type 1, structure 4 5t04 Rattus norvegicus Eukaryo. plasma 1 7 31.4 ± 0.8 7 ± 1 -69.8
1.2.43.01. Envelope glycoprotein, Zika virus, structure 6 5gzn Zika virus Viral 1 0 5.1 ± 2.6 41 ± 11 -4.9
2.1.14.02. SusD superfamily protein 3myv Bacteroides vulgatus Secreted 1 0 4.0 ± 1.0 64 ± 2 -6.0
1.3.14.01. Toluene transporter TbuX 3bry Ralstonia pickettii Bact. Gram-neg outer 1 14 25.4 ± 1.5 1 ± 2 -57.7
2.2.11.01. Protein kinase C eta, C2 domain 2fk9 Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.1 57 ± 6 -5.0
2.4.07.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Homo sapiens Golgi 1 0 2.5 ± 1.3 56 ± 16 -4.8
2.2.41.01. Neutrophil defensin 1 2pm1 Homo sapiens Secreted 1 0 3.6 ± 1.3 85 ± 6 -3.8
1.1.25.06. D-xylose-proton symporter xylE, conformation 2 4ja3 Escherichia coli Bact. Gram-neg inner 1 12 29.8 ± 1.0 4 ± 1 -87.6
3.1.02.05. Acetylcholine receptor, subunit beta2, TMH 2 2k59 Homo sapiens Eukaryo. plasma 1 1 30.2 ± 1.9 20 ± 4 -21.0
1.1.95.01. Acyl-CoA desaturase 4zyo Homo sapiens Endoplasm. reticulum 1 4 29.2 ± 2.4 3 ± 1 -59.1
1.2.39.02. Matrilysin, structure 3 2mzh Homo sapiens Secreted 1 0 2.2 ± 1.6 67 ± 22 -6.4
2.2.05.01. Amicyanin 1id2 Paracoccus versutus Bact. Gram-neg inner 1 0 4.2 ± 1.3 52 ± 8 -4.9
2.2.06.02. Fatty acid-binding protein 1ftp Schistocerca gregaria Eukaryo. plasma 1 0 4.5 ± 1.0 53 ± 11 -5.2
1.2.54.01. Dihydroorotate dehydrogenase 1uum Rattus norvegicus Mitochon. inner 1 0 6.9 ± 0.4 50 ± 6 -6.3
1.2.40.01. Mitochondria fission 1 protein, NMR 1pc2 Homo sapiens Mitochon. outer 1 0 8.5 ± 2.5 48 ± 23 -8.0
3.1.19.01. Paracelsin X 4by8 Trichoderma reesei Secreted 1 0 14.6 ± 5.1 60 ± 4 -14.6
2.2.23.01. Lipoprotein BamB, conformation 1 3prw Escherichia coli Bact. Gram-neg outer 1 0 5.1 ± 1.2 81 ± 7 -8.5
1.1.01.02. Free fatty acid receptor 1 4phu Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 10 ± 1 -59.2
1.2.41.01. Acyl-CoA-binding protein 2cb8 Homo sapiens Peroxisome 1 0 2.7 ± 2.0 74 ± 29 -5.2
2.4.16.02. Phormicin 1ica Protophormia terraenovae (Northern blowfly) Secreted 1 0 3.7 ± 2.3 90 ± 23 -5.0
2.4.15.01. Protein Nef (HIV 9HIV1) 2xi1 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 4.3 ± 0.6 57 ± 5 -5.0
2.4.11.01. Alpha-1-purothionin 2plh Triticum aestivum Secreted 1 0 2.4 ± 2.0 53 ± 17 -4.6
2.3.06.04. Palmitoyl protein thioesterase 1 1eh5 Bos taurus Lysosome 1 0 5.3 ± 0.9 59 ± 6 -8.1
1.1.44.01. DsbB - DsbA complex, conformation 1 2hi7 Escherichia coli Bact. Gram-neg inner 1 4 24.3 ± 3.0 30 ± 0 -34.9
3.1.19.01. Chrysospermin C 1ee7 Apiocrea chrysosperma Secreted 1 0 9.8 ± 2.3 82 ± 12 -12.2
1.3.20.01. Fe-regulated protein B, different variant 4aiq Neisseria meningitidis Bact. Gram-neg outer 1 22 23.6 ± 0.9 6 ± 0 -69.7
2.2.06.02. Fatty acid-binding protein, epidermal 4azp Mus musculus Eukaryo. plasma 1 0 4.2 ± 2.4 57 ± 11 -5.5
3.1.07.02. Juxtamembrane peptide (684-719) of protein gp41 2kzq Hepatitis C virus Endosome 1 0 4.3 ± 3.3 88 ± 0 -9.9
2.1.45.01. Antifungal peptide 2l2r Echinochloa crus-galli Secreted 1 0 3.4 ± 1.5 50 ± 8 -3.8
2.4.33.01. 72 kDa type IV collagenase, 32-452 1eak Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.6 37 ± 6 -6.6
2.1.24.01. Pulmonary surfactant-associated protein B fragments 2dwf Homo sapiens Secreted 1 0 5.6 ± 1.3 77 ± 4 -9.5
3.4.07.01. Antimicrobial cationic cyclic hexapeptide 1qvl Designed proteins Undefined 1 0 4.2 ± 1.6 84 ± 15 -6.8
2.1.01.01. Snake phospholipase A2, group II, VRV-PL-VIIIa 1zwp Daboia russelli pulchella Secreted 1 0 4.9 ± 1.0 76 ± 7 -12.5
3.4.01.01. Contryphan-In 2m6d Conus inscriptus Secreted 1 0 8.2 ± 1.0 57 ± 15 -5.8
3.1.01.05. Proteinase inhibitor, vacuolar targeting peptide (372-397) 1vtp Nicotiana alata (Winged tobacco) Vacuole 1 0 3.5 ± 1.1 87 ± 4 -4.2
3.1.11.02. Pituitary adenylate cyclase activating polypeptide (PACAP)-38 2d2p Homo sapiens Secreted 1 0 3.9 ± 4.0 90 ± 0 -6.8
1.2.07.01. Protein jagged-1 2vj2 Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.8 84 ± 8 -5.8
1.2.33.02. Alpha-glycerophosphate oxidase (GlpO) 2rgh Streptomyces sp. Bact. Gram-pos plas. 1 0 3.9 ± 1.4 71 ± 12 -6.2
3.1.26.01. Piscidin 1 2ojm Morone saxatilis Secreted 1 0 10.6 ± 1.0 82 ± 13 -16.3
2.3.22.01. Uncharacterized protein 1rtt Pseudomonas aeruginosa Undefined 1 0 3.1 ± 2.5 70 ± 22 -4.1
1.1.25.04. L-fucose-proton symporter fucP 3o7q Escherichia coli Bact. Gram-neg inner 1 12 30.7 ± 1.3 6 ± 0 -85.3
1.2.32.01. Cytochrome P450 2B4, open state 1 2bdm Oryctolagus cuniculus Endoplasm. reticulum 1 0 10.6 ± 1.0 48 ± 15 -16.2
2.2.34.11. Kalata B2, segment 71-98 (repeat 1) 1pt4 Oldenlandia affinis Secreted 1 0 4.6 ± 1.2 83 ± 14 -9.2
2.1.60.03. Pseudecin, conformation 2 2epf Pseudechis porphyriacus Secreted 1 0 5.4 ± 1.1 86 ± 1 -4.6
1.1.12.01. Potassium channel KvAP, sensor domain 1ors Aeropyrum pernix Archaebac. 1 5 31.5 ± 2.2 19 ± 1 -50.3
1.3.15.02. CymA protein, conformation 3 4v3g Klebsiella oxytoca Bact. Gram-neg outer 1 14 23.4 ± 1.5 3 ± 3 -45.0
1.1.01.02. Opioid mu receptor, active state 5c1m Mus musculus Eukaryo. plasma 1 7 34.4 ± 2.9 9 ± 0 -83.2
2.2.11.01. Synaptotagmin-like protein 4 3fdw Homo sapiens Vesicle 1 0 3.0 ± 2.0 71 ± 17 -3.6
2.2.34.02. Delta-amaurobitoxin-Pl1b 1v91 Pireneitega luctuosa (Tangled nest spider) Secreted 1 0 2.4 ± 0.9 35 ± 4 -5.7
1.1.69.01. HIG1 domain family member 1B 2lon Homo sapiens Eukaryo. plasma 1 2 22.4 ± 1.2 19 ± 0 -13.7
2.1.47.01. Group 2 truncated hemoglobin glbO 2qrw Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 4.5 ± 1.0 52 ± 3 -5.5
2.3.06.09. Cutinase 1 3dcn Colletotrichum gloeosporioides Secreted 1 0 5.7 ± 1.2 44 ± 8 -10.1
3.1.05.03. LAK160-P10 2l99 Designed proteins Undefined 1 0 3.9 ± 2.6 84 ± 0 -5.0
1.1.02.05. Light-harvesting protein B-875, beta chain 1jo5 Rhodobacter sphaeroides Bact. Gram-neg inner 1 1 29.6 ± 1.5 20 ± 2 -24.7
1.2.32.01. Cytochrome P450 2B6, conformation 1 3ibd Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 1.0 57 ± 3 -10.8
2.4.16.02. Defensin ARD1 1ozz Archaeoprepona demophon Secreted 1 0 4.9 ± 1.7 31 ± 17 -7.1
3.1.29.01. Fowlicidin-2 2gdl Gallus gallus Secreted 1 0 3.1 ± 0.5 85 ± 4 -8.9
1.1.12.01. Potassium channel KvAP, sensor domain, NMR model 2kyh Aeropyrum pernix Archaebac. 1 5 28.6 ± 1.4 19 ± 4 -44.6
3.1.07.01. Fusion peptide (524-539) of ebolavirus glycoprotein GP2 2rlj Zaire ebolavirus Viral 1 0 5.8 ± 1.8 84 ± 6 -6.8
3.1.11.01. Neuropeptide F 1k8v Moniezia expansa (Sheep tapeworm) Secreted 1 0 2.9 ± 1.1 68 ± 9 -7.0
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, more complete 4ezk Homo sapiens Eukaryo. plasma 1 0 3.6 ± 0.6 81 ± 2 -5.1
1.1.25.05. Proton-dependent oligopeptide transporter, conformation 2 4iky Geobacillus kaustophilus Bact. Gram-pos plas. 1 14 31.8 ± 1.3 4 ± 0 -115.6
3.2.01.09. Transthyretin-derived peptide 5hpp Designed proteins Undefined 1 0 2.7 ± 1.6 83 ± 6 -5.2
1.1.01.02. Rhodopsin, active (metarhodopsin II), complex with peptide of transducin 3pqr Bos taurus Eukaryo. plasma 1 7 31.8 ± 1.1 9 ± 1 -78.3
2.3.06.01. Bile-salt activated lipase, structure 1 1f6w Homo sapiens Secreted 1 0 1.8 ± 0.5 81 ± 10 -5.1
2.3.06.01. Carboxylic ester hydrolase, closed state 4be4 Ophiostoma piceae Secreted 1 0 6.4 ± 2.3 61 ± 4 -5.7
1.1.82.01. Bacteriochlorophyll synthase 4tq4 Archaeoglobus fulgidus Archaebac. 1 9 29.2 ± 1.5 14 ± 1 -73.5
1.2.50.02. Nakanori protein 5h0q Grifola frondosa Eukaryo. plasma 1 0 0.9 ± 1.8 37 ± 15 -3.1
2.1.18.01. Annexin VI 1m9i Homo sapiens Eukaryo. plasma 1 0 2.8 ± 0.3 82 ± 0 -8.5
1.2.43.01. Envelope glycoprotein, Dengue virus type 3 1uzg Dengue virus Viral 1 0 5.7 ± 2.7 18 ± 7 -5.4
2.1.52.01. Pheromone binding protein 1ow4 Rhyparobia maderae (Madeira cockroach) Secreted 1 0 4.4 ± 0.8 30 ± 16 -4.4
1.2.54.01. Dihydroorotate dehydrogenase 1f76 Escherichia coli Bact. Gram-neg outer 1 0 3.7 ± 0.8 24 ± 8 -8.7
2.4.16.01. Alpha-mammal toxin BmK-M8 1snb Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.4 ± 2.4 79 ± 22 -2.3
2.2.20.01. FYVE, RhoGEF and PH domain-containing protein 6 1wgq Mus musculus Eukaryo. plasma 1 0 2.5 ± 1.8 68 ± 17 -3.2
3.1.19.01. Trichotoxin a50e 1m24 Trichoderma viride Secreted 1 0 10.4 ± 1.8 75 ± 32 -14.3
1.1.15.01. Nicotinic acetylcholine receptor, beta-2, in hexafluoroisopropanol/water 2ksr Homo sapiens Eukaryo. plasma 1 4 29.1 ± 2.2 16 ± 1 -47.0
1.2.09.01. Stannin 1zza Homo sapiens Mitochon. outer 1 1 30.0 ± 2.0 13 ± 2 -25.2
1.3.20.01. Outer membrane heme transporter ShuA 3fhh Shigella dysenteriae Bact. Gram-neg outer 1 22 24.6 ± 0.9 5 ± 0 -70.7
1.1.01.02. P2Y purinoceptor 12 4ntj Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 9 ± 0 -79.8
2.3.05.06. Endothelin-converting enzyme 2 2pxx Homo sapiens Golgi 1 0 7.1 ± 1.3 37 ± 8 -8.4
3.2.01.07. Protegrin-1 1pg1 Sus scrofa Secreted 1 0 2.2 ± 0.4 72 ± 4 -4.2
3.1.04.03. Viral protein R, peptide 59-86 1dsk Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 9.5 ± 0.4 65 ± 6 -11.7
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1gym Bacillus cereus Secreted 1 0 4.9 ± 1.0 67 ± 11 -7.2
3.1.08.01. Ice-structuring protein SS-3 1y04 Myoxocephalus scorpius Secreted 1 1 4.2 ± 3.8 90 ± 5 -6.7
2.3.02.01. Phospholipase C-delta isoform 1 1djx Rattus norvegicus Eukaryo. plasma 1 0 4.1 ± 0.9 68 ± 5 -7.2
2.3.05.01. Flavoprotein-ubiquinone oxydoreductase 2gmh Sus scrofa Mitochon. inner 1 0 7.2 ± 0.8 38 ± 4 -18.5
2.3.06.02. Antigen 85c, conformation 2 4qdu Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 5.3 ± 2.4 87 ± 16 -5.2
3.1.28.06. Magainin 2, Ala-analogue 4mgp Designed proteins Secreted 1 0 10.0 ± 4.1 79 ± 2 -15.1
1.3.19.01. Pyroglutamate porin OpdO 2y0k Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.8 ± 1.2 1 ± 0 -55.8
3.1.28.04. Phylloseptin-1 2jq0 Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 9.5 ± 1.4 76 ± 7 -13.5
3.1.03.04. Anchor helix of protein yopD (peptide 278-300) 1kdl Yersinia pseudotuberculosis Eukaryo. plasma 1 0 5.7 ± 0.8 86 ± 12 -5.0
2.2.05.01. Plastocyanin 1bxv Synechocystis sp. Thylakoid 1 0 2.0 ± 1.6 36 ± 19 -2.6
2.2.08.01. Osmotin-like protein 1aun Nicotiana tabacum Secreted 1 0 5.8 ± 1.0 85 ± 11 -6.7
2.1.24.01. Saposin A (peptide 60-140), conformation in disc 4ddj Homo sapiens Lysosome 1 0 6.4 ± 0.9 89 ± 3 -8.5
1.1.25.02. Lactose permease LacY, structure 5 4oaa Escherichia coli Bact. Gram-neg inner 1 12 32.6 ± 1.6 2 ± 2 -101.7
2.2.20.01. PH domain of 3-phosphoinositide-dependent protein kinase 1 1w1g Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 20 ± 18 -4.8
1.1.34.01. Mitochondrial ADP-ATP carrier, conformation 1 4c9g Saccharomyces cerevisiae Mitochon. inner 1 6 31.4 ± 1.5 1 ± 1 -54.6
2.1.01.01. Snake phospholipase A2, group I 1poa Naja atra Secreted 1 0 4.8 ± 1.0 89 ± 7 -10.7
1.2.55.01. Neutral ceramidase, structure 2 2zxc Pseudomonas aeruginosa Secreted 1 0 4.6 ± 1.7 71 ± 8 -7.6
3.1.02.02. S5P linker peptide (570-611) of HERG K+ channel 1ujl Homo sapiens Eukaryo. plasma 1 0 4.6 ± 0.3 89 ± 7 -7.6
2.4.04.01. Inositol polyphosphate 5-phosphatase OCRL-1 4cmn Homo sapiens Endosome 1 0 6.7 ± 1.6 83 ± 2 -9.2
3.4.02.06. Epilancin 15X 1w9n Staphylococcus epidermidis Secreted 1 0 2.9 ± 1.0 72 ± 7 -5.0
1.2.03.02. T-cell-specific surface glycoprotein CD28 1yjd Homo sapiens Eukaryo. plasma 1 0 4.5 ± 0.6 46 ± 11 -3.6
3.2.02.02. T-2-conotoxin MrIA 2ew4 Conus marmoreus Secreted 1 0 2.5 ± 1.5 81 ± 19 -3.0
3.1.07.03. Antimicrobial peptide derived from hemagglutinin 2l24 Influenza virus Undefined 1 0 8.7 ± 1.3 75 ± 10 -12.6
2.2.27.01. Beta-chimaerin 1xa6 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 1.7 65 ± 7 -5.1
1.2.32.01. Cytochrome P450 2C9, structure 1 1og5 Homo sapiens Endoplasm. reticulum 1 0 7.6 ± 1.0 79 ± 6 -13.7
2.1.28.01. Heat-stable enterotoxin II 1ehs Escherichia coli Secreted 1 0 1.4 ± 1.1 64 ± 11 -6.0
3.4.12.01. Actinomycin X2 1qfi Streptomyces antibioticus Secreted 1 0 15.2 ± 2.3 35 ± 34 -14.1
1.3.02.01. Opacity protein opA60, structure 2 2mlh Neisseria gonorrhoeae Bact. Gram-neg outer 1 8 23.2 ± 2.7 13 ± 2 -30.2
1.1.01.02. P2Y purinoceptor 1, conformation 2 4xnw Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.3 5 ± 1 -72.0
1.1.71.01. SidF, inhibitor of growth family, member 3 4fyg Legionella pneumophila Vacuole 1 0 8.1 ± 3.3 81 ± 10 -3.9
2.4.17.01. Vitellogenin 1lsh Ichthyomyzon unicuspus (Silver lamprey) Secreted 1 0 3.4 ± 1.3 81 ± 0 -4.6
1.1.26.07. STAS domain of sulfate permease 4dgf Wolinella succinogenes Bact. Gram-neg inner 1 0 2.6 ± 0.5 51 ± 2 -7.0
1.2.04.01. Integrin alpha-1, 1135-1179 peptide 2l8s Homo sapiens Eukaryo. plasma 1 1 32.0 ± 3.7 40 ± 1 -34.5
2.1.01.01. Snake phospholipase A2, acidic, group II 1ijl Agkistrodon acutus Secreted 1 0 4.2 ± 1.2 83 ± 12 -7.5
2.3.13.04. Glutathione peroxidase-like protein 2vup Trypanosoma brucei Undefined 1 0 3.0 ± 1.7 84 ± 7 -4.1
1.1.02.05. Light-harvesting complex LH1, alpha chain 1xrd Rhodospirillum rubrum Bact. Gram-neg inner 1 1 30.3 ± 3.1 30 ± 4 -30.5
1.2.32.01. Prostacyclin synthase (cytochrome P450 8A1) 3b6h Homo sapiens Endoplasm. reticulum 1 0 5.0 ± 1.6 64 ± 18 -6.3
2.2.34.01. Mu-O conotoxin MrVIB 1rmk Conus marmoreus Secreted 1 0 10.1 ± 1.3 62 ± 19 -10.7
3.1.11.01. Neuropeptide Y analogue 1icy Sus scrofa Secreted 1 0 6.4 ± 0.5 69 ± 6 -8.1
1.1.01.01. Archaerhodopsin-2, monomer 1vgo Halobacterium sp. Archaebac. 1 7 30.7 ± 1.3 18 ± 2 -73.1
1.3.17.02. BamA domains 3efc Escherichia coli Bact. Gram-neg outer 1 0 4.2 ± 2.2 85 ± 9 -5.5
2.2.11.01. C2A domain of synaptotagmin-5 5h4y Homo sapiens Vesicle 1 0 2.3 ± 2.3 29 ± 11 -4.5
3.1.20.01. Alpha-conotoxin EIVA 1pqr Conus ermineus Secreted 1 0 2.5 ± 1.3 14 ± 14 -3.4
2.3.04.01. Tyrosine-protein phosphatase CpsB 2wje Streptococcus pneumoniae Bact. Gram-pos plas. 1 0 4.2 ± 2.8 76 ± 26 -4.6
2.2.34.11. Vodo peptide N 2aks Viola odorata Secreted 1 0 4.0 ± 1.4 89 ± 22 -6.7
3.1.05.03. LAK160-P7 2l96 Designed proteins Undefined 1 0 1.4 ± 0.9 88 ± 5 -2.7
1.2.32.01. Cytochrome P450 1n97 Thermus thermophilus Bact. Gram-neg inner 1 0 5.2 ± 0.3 43 ± 5 -9.9
2.1.02.01. Seed lipoxygenase-1 1yge Glycine max Eukaryo. plasma 1 0 3.0 ± 2.6 68 ± 3 -6.4
2.1.17.01. Small hydrophilic endoplasmic reticulum-associated protein (Sherp) 2x43 Leishmania major Endoplasm. reticulum 1 0 4.1 ± 0.3 82 ± 2 -9.0
2.2.39.01. Cardiotoxin II (cytotoxin II) 1ffj Naja naja oxiana Secreted 1 0 7.9 ± 0.8 56 ± 5 -13.7
3.2.06.01. Growth-blocking peptide 2djc Spodoptera litura Secreted 1 0 2.9 ± 2.0 19 ± 14 -3.1
1.3.07.01. Plasminogen activator PLA (coagulase/fibrinolysin) 2x55 Yersinia pestis Bact. Gram-neg outer 1 10 25.6 ± 1.9 4 ± 5 -43.9
3.4.02.03. Lantibiotic 107891 2mh5 Microbispora sp. Bact. Gram-pos plas. 1 0 7.3 ± 3.0 72 ± 38 -4.0
2.2.12.01. Lymphocyte antigen 86 3mtx Gallus gallus Secreted 1 0 2.3 ± 1.6 69 ± 11 -2.4
2.3.18.01. Choline O-acetyltransferase 2fy2 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 2.2 87 ± 17 -5.2
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 6 2zbe Oryctolagus cuniculus Endoplasm. reticulum 1 10 28.0 ± 0.7 16 ± 0 -55.4
2.3.06.06. Type-B carboxylesterase/lipase 1cle Candida cylindracea Secreted 1 0 10.2 ± 0.0 83 ± 0 -24.7
2.3.01.06. Glycosyl hydrolase PslG 5bxa Pseudomonas aeruginosa Secreted 1 0 6.0 ± 1.2 72 ± 9 -6.9
1.2.32.01. Cytochrome P450 2B4, closed state 3 3g5n Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.7 ± 1.8 65 ± 3 -12.1
2.4.04.01. Sphingomyelinase C 1zwx Listeria ivanovii Secreted 1 0 6.2 ± 0.5 55 ± 1 -10.1
2.3.06.12. Lipase/esterase 3bjr Lactobacillus plantarum Secreted 1 0 2.1 ± 0.2 72 ± 5 -7.0
2.1.20.01. Prothrombin 1nl2 Bos taurus Eukaryo. plasma 1 0 3.9 ± 3.0 18 ± 24 -5.8
1.1.01.03. Glucagon receptor, structure 2 5ee7 Homo sapiens Eukaryo. plasma 1 7 31.4 ± 1.4 19 ± 3 -66.2
2.2.21.05. Kunitz-type proteinase inhibitor BbCI 2gzb Bauhinia bauhinioides Secreted 1 0 7.9 ± 0.3 28 ± 3 -9.3
2.1.10.01. Ceramide-1-phosphate transfer protein 4k8n Homo sapiens Eukaryo. plasma 1 0 7.0 ± 1.0 81 ± 4 -10.6
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 1 1zhx Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.9 90 ± 7 -5.0
2.1.42.01. PapB 2ip6 Pediococcus pentosaceus Secreted 1 0 0.6 ± 2.6 72 ± 23 -2.2
1.2.03.02. Hepatitis A virus cellular receptor 2 homolog 3kaa Mus musculus Eukaryo. plasma 1 0 2.8 ± 2.0 55 ± 16 -5.5
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 8 4c0c Trypanosoma cruzi Endoplasm. reticulum 1 0 9.4 ± 1.9 64 ± 7 -10.9
3.2.03.01. Hepcidin, structure 2 1m4f Homo sapiens Secreted 1 0 5.9 ± 1.2 76 ± 18 -6.4
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3a 5fc1 Mus musculus Secreted 1 0 2.3 ± 3.0 62 ± 17 -4.8
1.2.12.01. Fimbrial protein, type IV pilin, monomer 2pil Neisseria gonorrhoeae Bact. Gram-neg inner 1 1 30.8 ± 5.7 21 ± 5 -24.9
2.4.16.05. Eurocin 2lt8 Eurotium amstelodami Secreted 1 0 5.3 ± 1.3 84 ± 12 -5.5
1.3.20.01. Outer membrane cobalamin transporter BtuB, with cyanocobalamin 3m8d Escherichia coli Bact. Gram-neg outer 1 22 23.3 ± 0.8 6 ± 1 -70.5
2.2.11.01. Extended synaptotagmin-2, SMP-C2A-C2B domains 4p42 Homo sapiens Eukaryo. plasma 1 0 5.5 ± 2.8 67 ± 6 -3.3
2.3.06.12. Gibberellin receptor GID1 3ebl Oryza sativa (Rice) Nuclear inner 1 0 5.2 ± 1.5 59 ± 14 -9.1
3.1.15.01. Curvacin-A 2a2b Lactobacillus curvatus Secreted 1 0 2.5 ± 1.3 34 ± 18 -6.7
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase SMURF1 3pyc Homo sapiens Eukaryo. plasma 1 0 4.5 ± 2.1 23 ± 17 -5.7
1.2.32.01. Cytochrome P450 2B4, closed state, mutant 5iut Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.3 ± 0.5 56 ± 2 -13.0
2.2.06.01. Retinol binding protein, plasma isoform 1iiu Gallus gallus Secreted 1 0 1.9 ± 1.8 35 ± 17 -4.4
2.2.34.02. beta-TRTX-Pre1a toxin 5i1x Psalmopoeus cambridgei (Trinidad chevron tarantula) Secreted 1 0 5.0 ± 1.6 52 ± 12 -6.3
2.4.06.01. Cholesterol-regulated Start protein 4 (StarD4) 5brl Mus musculus Eukaryo. plasma 1 0 3.7 ± 1.1 67 ± 13 -3.7
2.4.16.01. Toxin CsEv3 2sn3 Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.3 74 ± 17 -5.5
1.3.20.01. Transferrin-binding protein A, complex with full-length transferrin 3v8x Neisseria meningitidis Bact. Gram-neg outer 1 22 23.2 ± 0.6 3 ± 0 -66.6
2.4.07.01. Sorting nexin-23 (Kinesin-like protein KIF16B) 2v14 Homo sapiens Endosome 1 0 3.3 ± 3.0 72 ± 14 -5.4
2.4.16.03. Chlorotoxin 1chl Leiurus quinquestriatus quinquestriatus Secreted 1 0 6.5 ± 1.2 87 ± 14 -4.3
1.1.25.05. Bacterial proton:oligopeptide symporter, structure 3 4tpj Shewanella oneidensis Bact. Gram-neg inner 1 14 30.6 ± 0.9 9 ± 0 -90.0
2.1.01.01. Snake phospholipase A2 2i0u Vipera nikolskii Secreted 1 0 5.6 ± 0.9 88 ± 9 -15.2
2.3.13.06. Chloride intracellular channel protein 1 1rk4 Homo sapiens Nuclear outer 1 0 3.0 ± 1.0 40 ± 5 -5.5
2.1.15.03. Clathrin assembly lymphoid myeloid leukemia (CALM) protein 1hfa Rattus norvegicus Eukaryo. plasma 1 0 14.2 ± 2.0 44 ± 14 -17.9
2.1.01.01. Snake phospholipase A2, group II 1oz6 Echis carinatus Secreted 1 0 5.6 ± 1.0 84 ± 13 -9.6
2.4.16.02. Lucifensin 2lld Lucilia sericata Secreted 1 0 1.1 ± 1.7 11 ± 12 -3.0
1.3.19.01. Porin OprdG 4ft6 Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.4 ± 1.4 4 ± 0 -62.4
3.1.07.01. Fusion peptide (1185-1201) of spike glycoprotein 2run Human SARS coronavirus Endosome 1 0 6.8 ± 4.0 74 ± 7 -10.7
2.2.58.01. Cone arrestin 1suj Ambystoma tigrinum (Tiger salamander) Eukaryo. plasma 1 0 1.4 ± 0.8 82 ± 12 -4.7
2.4.01.01. Cholesterol oxidase 1coy Brevibacterium sterolicum Bact. Gram-pos plas. 1 0 4.4 ± 1.1 43 ± 10 -6.8
2.1.03.01. Alpha-toxin (PHLC_CLOP1) , different conformation 1qmd Clostridium perfringens Secreted 1 0 4.8 ± 1.0 80 ± 8 -6.7
2.3.24.02. Phosphoglycolate phosphatase 1l6r Thermoplasma acidophilum Undefined 1 0 3.6 ± 0.5 86 ± 3 -7.5
1.1.47.01. Aerobic respiration control sensor protein acrB 2ksd Escherichia coli Bact. Gram-neg inner 1 2 27.9 ± 2.8 9 ± 1 -33.6
2.2.20.01. Spectrin beta chain 1btn Mus musculus Eukaryo. plasma 1 0 13.7 ± 1.6 57 ± 19 -17.3
1.2.39.01. Endoplasmic reticulum aminopeptidase 1 3mdj Homo sapiens Endoplasm. reticulum 1 0 1.9 ± 3.6 63 ± 10 -4.6
1.1.01.02. Lysophosphatidic acid receptor 1 4z34 Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.3 13 ± 1 -74.7
2.2.34.01. Conotoxin TVIIA 1eyo Conus tulipa (Fish-hunting cone snail) Secreted 1 0 2.2 ± 0.7 74 ± 9 -4.6
2.3.06.12. Esterase LipW 3qh4 Mycobacterium marinum Bact. Gram-pos plas. 1 0 2.4 ± 1.2 76 ± 32 -5.0
2.1.01.01. Snake phospholipase A2, acidic 2h4c Daboia russellii siamensis Secreted 1 0 5.7 ± 1.1 88 ± 10 -9.0
2.2.09.02. Diisopropyl-fluorophosphatase 3o4p Loligo vulgaris (Common European squid) Undefined 1 0 4.6 ± 1.3 82 ± 5 -6.6
1.1.60.01. Protease GlpG, conformation 1 2xtv Escherichia coli Bact. Gram-neg inner 1 6 28.8 ± 1.6 14 ± 1 -61.1
2.2.04.01. Retinoid isomerohydrolase, conformation 1 3fsn Bos taurus Eukaryo. plasma 1 0 7.8 ± 1.0 73 ± 10 -10.3
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3l4d Leishmania infantum Endoplasm. reticulum 1 0 8.4 ± 1.8 66 ± 9 -12.6
2.2.34.04. Albumin 1 subunit B (Pab1) 1p8b Pisum sativum Secreted 1 0 11.1 ± 0.9 40 ± 13 -8.2
3.2.05.02. Caulonodin 2mlj