PDB ID or protein name

All proteins in OPM (3450 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.1.25.03. Enterocin 7A 2m5z Enterococcus faecalis Secreted 0 0 4.4 ± 0.3 57 ± 3 -5.3
2.1.63.01. Phosphatidylinositol mannoside acyltransferase PatA 5f34 Mycobacterium smegmatis Bact. Gram-pos plas. 0 0 3.9 ± 0.5 58 ± 1 -6.9
2.1.25.01. Bacteriocin AS-48 1o82 Enterococcus faecalis Secreted 1 0 4.4 ± 1.1 81 ± 13 -7.0
2.4.51.01. Heme acquisition protein HasA, alternative position of heme 3mol Pseudomonas aeruginosa Secreted 1 0 2.9 ± 0.6 40 ± 5 -5.8
1.3.19.02. Alginate export protein, AlgE, conformation 4 4xnk Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 24.4 ± 1.0 3 ± 0 -71.7
1.2.49.01. Tumor necrosis factor receptor 12A 2kmz Homo sapiens Eukaryo. plasma 1 0 5.9 ± 1.6 66 ± 3 -6.3
3.1.07.01. Probable fusion peptide (93-126, 138-160) of protein gp41 2mk3 Human immunodeficiency virus type 1 Endosome 1 2 20.8 ± 0.5 18 ± 1 -13.2
2.4.16.09. S-locus pollen protein 1ugl Brassica campestris (Field mustard) Secreted 1 0 1.3 ± 0.6 51 ± 5 -3.4
1.1.01.02. Opioid delta receptor 4ej4 Mus musculus Eukaryo. plasma 1 7 34.4 ± 0.8 11 ± 6 -73.2
2.3.19.01. Toxin B 2bvl Clostridium difficile Secreted 1 0 2.0 ± 1.1 24 ± 14 -4.2
1.1.28.04. Niemann-Pick C1 protein, NPC1 5i31 Homo sapiens Lysosome 1 12 30.8 ± 0.0 5 ± 0 -50.4
2.2.12.05. Glucans biosynthesis protein G 1txk Escherichia coli Bact. Gram-neg inner 1 0 2.3 ± 0.7 80 ± 8 -5.1
1.2.34.01. Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4) 2lat Homo sapiens Endoplasm. reticulum 1 1 31.8 ± 3.5 23 ± 16 -21.3
2.1.01.02. Phospholipase A2 1poc Apis mellifera Secreted 1 0 4.0 ± 1.6 60 ± 6 -9.5
3.4.08.02. Somatostatin 2mi1 Homo sapiens Secreted 1 0 5.6 ± 1.5 43 ± 15 -6.2
1.1.82.01. 4-hydroxybenzoate octaprenyltransferase 4od5 Aeropyrum pernix Archaebac. 1 9 29.8 ± 0.9 14 ± 1 -63.9
1.1.01.02. Muscarinic acetylcholine receptor M1 5cxv Homo sapiens Eukaryo. plasma 1 7 32.8 ± 0.7 4 ± 0 -78.2
1.1.01.02. 5-hydroxytryptamine receptor 1B, conformation 2 4iaq Homo sapiens Eukaryo. plasma 1 7 34.4 ± 1.7 6 ± 1 -77.4
2.2.35.01. Intermedilysin 1s3r Streptococcus intermedius Secreted 1 0 5.3 ± 2.0 61 ± 16 -5.6
3.1.06.01. Apolipoprotein E, peptide 281-304 1oef Homo sapiens Undefined 1 0 4.8 ± 0.9 88 ± 19 -5.5
1.2.32.01. Cytochrome P450 19A1 (estrogen synthetase) 3eqm Homo sapiens Endoplasm. reticulum 1 0 6.1 ± 1.2 58 ± 8 -12.4
2.2.34.06. Gurmarin 1c4e Gymnema sylvestre Secreted 1 0 3.9 ± 2.6 75 ± 16 -4.8
2.2.34.02. U1-theraphotoxin-Cj1a 2aap Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.6 ± 0.7 82 ± 5 -4.9
2.2.20.01. PH domain of phospholipase C delta 1 1mai Rattus norvegicus Eukaryo. plasma 1 0 15.0 ± 1.8 22 ± 14 -17.8
3.1.03.10. Lipid droplet anchoring peptide of CGI-58 5a4h Mus musculus Vesicle 1 0 3.9 ± 1.2 37 ± 7 -7.5
2.2.34.02. Omega-hexatoxin-Hv2a 1g9p Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 3.0 ± 1.4 78 ± 5 -4.0
1.3.20.01. Outer membrane cobalamin transporter BtuB 1nqe Escherichia coli Bact. Gram-neg outer 1 22 23.4 ± 1.0 5 ± 0 -68.8
2.3.04.01. Tyrosine-protein phosphatase CpsB 2wje Streptococcus pneumoniae Bact. Gram-pos plas. 1 0 4.2 ± 2.8 76 ± 26 -4.6
2.2.34.11. Kalata-B5 2kux Oldenlandia affinis Secreted 1 0 4.1 ± 1.0 61 ± 25 -6.6
2.4.23.01. Methyl-accepting chemotaxis protein 3eee Thermoanaerobacter tengcongensis Undefined 1 0 3.2 ± 0.9 81 ± 4 -5.9
1.1.60.01. Protease GlpG, conformation 3 2irv Escherichia coli Bact. Gram-neg inner 1 6 28.2 ± 1.3 23 ± 5 -48.1
2.4.05.01. Uncharacterized protein 3bkr Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.4 ± 6.2 50 ± 73 -1.2
2.2.02.03. Flavivirin protease NS2B 2wv9 Murray valley encephalitis virus Endoplasm. reticulum 1 0 1.6 ± 2.4 69 ± 8 -4.7
2.2.41.01. Beta-defensin 106 2lwl Homo sapiens Secreted 1 0 4.0 ± 1.5 70 ± 9 -6.4
2.1.08.01. Mono-heme c-type cytochrome ScyA 1kx7 Shewanella putrefaciens Bact. Gram-neg inner 1 0 1.8 ± 1.1 72 ± 12 -3.2
2.2.11.01. Synaptotagmin-3 3hn8 Rattus norvegicus Eukaryo. plasma 1 0 4.0 ± 3.1 74 ± 19 -4.0
1.1.01.02. C-C chemokine receptor type 9 5lwe Homo sapiens Eukaryo. plasma 1 7 33.0 ± 1.8 7 ± 0 -75.8
2.4.50.01. Matrix protein, Indiana virus 1lg7 Vesicular stomatitis virus Viral 1 0 2.7 ± 0.4 82 ± 2 -7.3
3.1.11.02. Extendin-4 1jrj Heloderma suspectum Secreted 1 0 1.7 ± 0.8 79 ± 8 -5.0
2.2.27.01. C1 domain of protein kinase C theta 2enn Homo sapiens Eukaryo. plasma 1 0 6.2 ± 1.9 89 ± 3 -7.5
3.4.02.03. Lantibiotic 107891 2mh5 Microbispora sp. Bact. Gram-pos plas. 1 0 7.3 ± 3.0 72 ± 38 -4.0
2.2.06.02. Der f 13 allergen 2a0a Dermatophagoides farinae (American house dust mite) Secreted 1 0 3.1 ± 1.3 50 ± 6 -3.5
3.1.21.01. Cecropin (1-7)-melittin (2-9) hybrid 2jmy Designed proteins Undefined 1 0 6.5 ± 3.3 77 ± 7 -6.1
1.2.04.01. Integrin beta-3, 742-788, biphosphorylated (747pY, 759pY) 2lje Homo sapiens Eukaryo. plasma 1 0 4.0 ± 0.5 74 ± 2 -7.0
1.1.09.01. Calcium ATPase, E1-2Ca state, conformation 3 1su4 Oryctolagus cuniculus Endoplasm. reticulum 1 10 30.0 ± 2.7 26 ± 1 -68.6
2.3.06.06. Triacylglycerol lipase, closed (inactive) state 3tgl Rhizomucor miehei Secreted 1 0 2.7 ± 1.1 39 ± 7 -5.8
2.2.35.01. Pneumolysin, structure 2 5cr6 Streptococcus pneumoniae Secreted 1 0 4.3 ± 1.9 24 ± 3 -6.4
2.1.08.01. Cytochrome c2 1cxa Rhodobacter sphaeroides Bact. Gram-neg inner 1 0 2.0 ± 1.2 88 ± 13 -4.3
2.2.06.02. Epidermal fatty acid binding protein 4lkt Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.2 39 ± 7 -6.7
2.3.06.01. Acetylcholinesterase 5x61 Anopheles gambiae (African malaria mosquito) Eukaryo. plasma 1 0 2.6 ± 1.5 37 ± 4 -4.0
2.4.16.03. Potassium channel toxin alpha-KTx 3.1 3odv Androctonus mauretanicus mauretanicus (Scorpion) Secreted 1 0 2.6 ± 0.9 84 ± 5 -5.1
2.1.07.01. Decaheme cytochrome c MtrF 3pmq Shewanella oneidensis Bact. Gram-neg outer 1 0 3.9 ± 0.9 86 ± 2 -6.2
2.4.16.01. Alpha-mammal toxin AaH2 1aho Androctonus australis (Sahara scorpion) Secreted 1 0 1.7 ± 1.0 64 ± 17 -3.4
1.1.46.01. MerF bacterial mercury uptake transporter, structure 3 2moz Morganella morganii Bact. Gram-neg inner 1 2 27.8 ± 1.9 16 ± 2 -33.5
1.2.53.01. Squalene synthase, conformation 3 3weh Homo sapiens Endoplasm. reticulum 1 0 1.4 ± 2.5 90 ± 26 -3.8
3.1.14.01. Neurokinin B 1p9f Homo sapiens Secreted 1 0 5.8 ± 1.2 89 ± 18 -6.8
2.2.34.07. Asteropsin A 3q8j Asteropus sp. Secreted 1 0 2.8 ± 1.7 75 ± 15 -3.0
2.3.14.02. Uncharacterized protein 2q3l Shewanella loihica Bact. Gram-neg inner 1 0 6.0 ± 0.5 64 ± 4 -12.6
2.1.18.01. Annexin IV, monomeric state 1ann Bos taurus Eukaryo. plasma 1 0 2.2 ± 1.0 77 ± 3 -6.0
1.2.22.01. Apoptosis regulator Bcl-2 1g5m Homo sapiens Mitochon. outer 1 0 4.2 ± 1.4 33 ± 11 -6.6
2.1.24.01. Saposin-like protein Ac-SLP-1 3s64 Ancylostoma caninum Secreted 1 0 4.2 ± 2.2 53 ± 16 -4.5
1.3.16.04. Porin B, low pH structure 4gf4 Pseudomonas putida Bact. Gram-neg outer 1 16 22.4 ± 1.1 5 ± 2 -54.3
3.1.02.02. S4-S5 linker peptide (532-551) of HERG K+ channel 2le7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.4 69 ± 9 -5.0
2.4.16.04. Defensin-like protein 1 1gpt Hordeum vulgare Secreted 1 0 3.1 ± 1.6 28 ± 18 -2.0
2.4.03.01. Tubby protein homolog 1s31 Homo sapiens Eukaryo. plasma 1 0 6.8 ± 1.0 71 ± 2 -7.6
3.4.03.01. Heat-stable enterotoxin ST-IA/ST-P 1etn Escherichia coli Secreted 1 0 3.0 ± 3.7 33 ± 39 -2.1
2.2.35.01. Pneumolysin, structure 6 5aof Streptococcus pneumoniae Secreted 1 0 2.9 ± 2.4 33 ± 9 -5.7
2.3.06.02. Antigen 85c, conformation 1 1va5 Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 4.2 ± 0.2 34 ± 3 -8.2
2.2.59.01. Zymogen granule membrane protein 16 3vy7 Homo sapiens Secreted 1 0 3.6 ± 2.1 54 ± 15 -4.6
1.3.17.02. Outer membrane protein assembly factor BamA 4k3b Neisseria gonorrhoeae Bact. Gram-neg outer 1 16 23.0 ± 1.1 9 ± 0 -52.6
1.1.20.03. Claudin-19 3x29 Mus musculus Eukaryo. plasma 1 4 31.6 ± 1.9 22 ± 1 -48.8
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-bound 1o7k Homo sapiens Endosome 1 0 15.2 ± 1.7 60 ± 15 -18.4
2.2.33.01. Antifungal peptide 2 1p9z Eucommia ulmoides (Hardy rubber tree) Secreted 1 0 3.5 ± 2.0 84 ± 18 -2.9
2.3.05.05. RabGDI protein 3p1w Plasmodium falciparum Eukaryo. plasma 1 0 6.6 ± 1.4 47 ± 3 -6.8
2.2.05.01. Plastocyanin 1bxv Synechocystis sp. Thylakoid 1 0 2.0 ± 1.6 36 ± 19 -2.6
2.1.29.03. Apolipoprotein C-I, peptide 27-83 1ioj Homo sapiens Secreted 1 0 0.6 ± 1.8 80 ± 16 -2.8
2.1.19.01. Kappa-buthitoxin-Tt2b 2li3 Tityus trivittatus Secreted 1 0 0.8 ± 0.7 40 ± 6 -2.7
1.1.25.02. Lactose permease LacY, structure 2 2v8n Escherichia coli Bact. Gram-neg inner 1 12 31.8 ± 0.8 5 ± 0 -86.4
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1t6m Bacillus thuringiensis Secreted 1 0 3.8 ± 1.4 89 ± 13 -4.9
2.3.13.03. Thiol-disulfide interchange protein DsbA 1u3a Escherichia coli Bact. Gram-neg inner 1 0 2.2 ± 1.4 86 ± 8 -4.2
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1kcm Mus musculus Eukaryo. plasma 1 0 5.3 ± 1.4 59 ± 5 -11.0
1.1.09.01. Calcium ATPase, E1-ATP state 1t5s Oryctolagus cuniculus Endoplasm. reticulum 1 10 29.7 ± 1.6 22 ± 1 -58.6
2.1.01.01. Snake phospholipase A2, group II, neutral 1bjj Agkistrodon halys pallas Secreted 1 0 2.6 ± 0.7 86 ± 5 -8.4
3.2.01.06. Symmetrical θ-defensin, BTD-2 2lye Macaca mulatta Secreted 1 0 0.4 ± 2.9 80 ± 22 -1.5
2.4.05.01. Uncharacterized protein 3cnu Archaeoglobus fulgidus Archaebac. 1 0 7.6 ± 1.7 69 ± 20 -7.0
3.1.07.01. Fusion peptide (772-787) of spike glycoprotein 2rum Human SARS coronavirus Endosome 1 0 11.1 ± 1.1 57 ± 13 -10.8
3.1.21.01. Cecropin A (1-8) - magainin (1-12) hybrid 1d9j Hyalophora cecropia (Cecropia moth) Secreted 1 0 2.3 ± 0.9 90 ± 10 -6.4
1.1.38.02. Lipid II flippase MurJ, inward-facing conformation 5t77 Thermosipho africanus Bact. Gram-neg inner 1 14 30.6 ± 1.4 3 ± 0 -124.8
2.2.20.01. Fermitin family homolog 2 4f7h Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.4 72 ± 4 -4.2
2.4.01.01. Cholesterol oxidase 1coy Brevibacterium sterolicum Bact. Gram-pos plas. 1 0 4.4 ± 1.1 43 ± 10 -6.8
2.1.01.01. Phospholipase A2 bothropstoxin-2 2oqd Bothrops jararacussu Secreted 1 0 6.0 ± 0.6 85 ± 4 -7.8
3.1.05.06. Transportan 1smz Designed proteins Undefined 1 0 9.1 ± 0.8 87 ± 7 -8.9
2.2.06.01. Prostaglandin-H2 D-isomerase 2ktd Mus musculus Endoplasm. reticulum 1 0 0.0 ± 1.4 73 ± 14 -2.2
2.1.03.01. Alpha-toxin 1olp Clostridium absonum Secreted 1 0 2.8 ± 1.8 62 ± 11 -6.1
3.2.05.03. Bicyclic peptide BI-32169 3njw Streptomyces sp. Secreted 1 0 6.1 ± 0.3 86 ± 3 -9.9
1.1.26.01. Sodium-dependent serotonin transporter, outward-facing state 5i6x Homo sapiens Eukaryo. plasma 1 12 31.6 ± 1.4 10 ± 0 -90.7
2.2.34.01. Omega-conotoxin MVIIA 1mvi Conus magus Secreted 1 0 4.7 ± 1.9 68 ± 14 -4.0
2.3.06.12. Esterase LipW 3qh4 Mycobacterium marinum Bact. Gram-pos plas. 1 0 2.4 ± 1.2 76 ± 32 -5.0
2.1.01.01. Snake phospholipase A2, ammodytoxin C, group II 3g8h Vipera ammodytes ammodytes Secreted 1 0 4.1 ± 1.1 81 ± 8 -9.7
2.1.02.01. Arachidonate 5-lipoxygenase 3o8y Homo sapiens Eukaryo. plasma 1 0 2.1 ± 1.0 89 ± 4 -3.8
1.2.25.01. Phospholamban, monomer 1fjk Sus scrofa Endoplasm. reticulum 1 1 30.1 ± 3.2 38 ± 6 -28.3
2.2.34.02. Huwentoxin-1 1qk6 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.7 ± 1.5 88 ± 11 -5.1
2.3.06.06. Lipase 3zpx Ustilago maydis Secreted 1 0 5.8 ± 0.8 88 ± 1 -14.0
2.1.18.01. Annexin III 1axn Homo sapiens Eukaryo. plasma 1 0 2.7 ± 0.8 77 ± 11 -5.7
3.1.20.01. Alpha-conotoxin S1 1qmw Conus striatus Secreted 1 0 2.8 ± 2.6 43 ± 17 -2.5
1.1.01.02. Neurotensin receptor type 1, structure 2 4buo Rattus norvegicus Eukaryo. plasma 1 7 31.4 ± 1.4 6 ± 2 -62.6
3.1.08.01. Antifreeze protein A 1wfb Pseudopleuronectes americanus Secreted 1 0 2.8 ± 1.0 88 ± 1 -10.1
3.1.05.10. WALP19 - Pro8 peptide 2lco Designed proteins Undefined 1 0 9.0 ± 0.4 85 ± 4 -15.0
2.2.11.01. Rabphilin-3A 2k3h Mus musculus Eukaryo. plasma 1 0 1.7 ± 2.1 78 ± 16 -4.1
1.2.32.01. Cytochrome P450 2D6, conformation 2 3tda Homo sapiens Endoplasm. reticulum 1 0 8.0 ± 0.7 35 ± 7 -12.5
2.2.41.01. Beta-defensin 3 1kj6 Homo sapiens Secreted 1 0 2.7 ± 1.3 18 ± 18 -5.1
2.2.41.01. Paneth cell-specific alpha-defensin 1 2mxq Equus caballus Secreted 1 0 3.1 ± 0.6 75 ± 5 -7.2
2.2.07.01. Polyisoprenoid-binding protein 1wub Thermus thermophilus Bact. Gram-neg inner 1 0 2.9 ± 1.9 42 ± 13 -4.4
1.1.35.03. PH domain of fermitin family homolog 3 5l81 Mus musculus Eukaryo. plasma 1 0 3.8 ± 2.2 59 ± 7 -4.2
3.1.07.03. Hemagglutinin, fusion peptide 346-365, H1 subtype 2kxa Influenza virus Viral 1 0 10.3 ± 1.9 84 ± 13 -14.5
3.1.19.01. Trichovirin 3sbn Hypocrea rufa Secreted 1 1 26.9 ± 2.3 6 ± 3 -10.1
1.3.01.01. Outer membrane protein A from Klebsiella 2k0l Klebsiella pneumoniae Bact. Gram-neg outer 1 8 24.3 ± 2.3 18 ± 6 -26.8
2.4.03.01. Tubby protein 3c5n Homo sapiens Eukaryo. plasma 1 0 3.4 ± 0.4 75 ± 5 -7.6
2.2.34.02. Kappa-theraphotoxin-Pg1a 2wh9 Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 6.4 ± 1.0 57 ± 6 -9.2
3.2.01.09. Peptide PG-990 2n7o Designed proteins Undefined 1 0 7.9 ± 1.6 68 ± 21 -5.6
1.1.51.01. Vitamin K epoxide reductase, conformation 2 4nv2 Synechococcus sp. Bact. Gram-neg inner 1 5 29.6 ± 2.0 6 ± 0 -50.3
3.1.02.01. Beta-1 adrenergic receptor, peptide 345-359 1dep Meleagris gallopavo Eukaryo. plasma 1 0 4.4 ± 1.2 76 ± 16 -8.3
1.2.32.01. Prostaglandin I2 synthase 3b98 Danio rerio Endoplasm. reticulum 1 0 4.4 ± 1.3 65 ± 6 -4.7
2.3.06.07. Lipase 1cvl Chromobacterium viscosum Secreted 1 0 9.9 ± 1.0 53 ± 9 -8.7
2.2.34.01. Conotoxin muOxi-GVIIJ 2n8h Conus geographus (Geography cone) Secreted 1 0 4.0 ± 1.0 43 ± 5 -4.1
2.2.06.02. Fatty acid-binding protein Sm14 1vyf Schistosoma mansoni Eukaryo. plasma 1 0 5.1 ± 1.2 42 ± 18 -5.2
2.1.64.01. AFMP4P 5j5k Aspergillus fumigatus Eukaryo. plasma 1 0 3.9 ± 1.9 73 ± 13 -6.1
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 4 4ut9 Dengue virus Viral 1 0 5.5 ± 2.8 31 ± 8 -5.1
2.1.60.03. Cysteine-rich venom protein 1rc9 Trimeresurus stejnegeri Secreted 1 0 3.9 ± 0.7 73 ± 5 -5.1
1.3.01.02. Attachment invasion locus protein, complex with the heparin analogue 3qrc Yersinia pestis Bact. Gram-neg outer 1 8 24.6 ± 1.2 7 ± 5 -31.6
1.1.106.01. Phosphatidylglycerol phosphate phosphatase 5jki Bacillus subtilis Bact. Gram-pos plas. 1 6 28.6 ± 1.4 38 ± 0 -56.7
2.4.16.01. Beta-insect depressant toxin LqhIT2 2i61 Leiurus quinquestriatus hebraeus Secreted 1 0 4.3 ± 1.6 80 ± 21 -3.7
1.2.47.01. Nickel-cobalt-cadmium resistance protein NccX 4clv Alcaligenes xylosoxidans Bact. Gram-neg inner 1 0 3.1 ± 0.9 83 ± 0 -6.7
3.1.04.01. Protein STE5, peptide 44-67 2kgn Saccharomyces cerevisiae Eukaryo. plasma 1 0 6.4 ± 0.9 84 ± 7 -9.8
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 9 4ycl Oryctolagus cuniculus Endoplasm. reticulum 1 10 30.2 ± 1.6 23 ± 1 -68.9
3.1.20.01. alpha-conotoxin PNI1 1pen Conus pennaceus Secreted 1 0 5.2 ± 1.7 27 ± 19 -3.8
2.3.10.03. LPS heptosyltransferase II, WaaF 1psw Escherichia coli Bact. Gram-neg inner 1 0 3.1 ± 1.1 58 ± 8 -5.6
2.2.27.01. Diacylglycerol kinase delta 1r79 Homo sapiens Eukaryo. plasma 1 0 3.3 ± 1.6 34 ± 19 -4.9
1.3.22.01. VDAC-1 channel 3emn Mus musculus Mitochon. outer 1 19 23.4 ± 1.1 5 ± 1 -52.5
2.3.02.02. Phosphatidylinositol-specific phospholipase C 4f2t Staphylococcus aureus Secreted 1 0 4.3 ± 0.5 65 ± 5 -7.8
1.3.14.01. Fatty Acid Transporter FadL, D348R, open channel 3pgr Escherichia coli Bact. Gram-neg outer 1 14 25.4 ± 1.4 3 ± 1 -50.8
3.1.04.03. Viral protein R, peptide 50-82 1bde Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.8 ± 1.1 89 ± 24 -6.7
2.4.25.01. N-alpha-acetyltransferase 60, structure 1 5hgz Homo sapiens Golgi 1 0 5.7 ± 1.1 41 ± 7 -8.5
3.1.28.04. Phylloseptin-2 2jpy Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 5.8 ± 1.3 86 ± 4 -15.2
1.1.15.01. Nicotinic acetylcholine receptor, beta-2, in LDAO micelles 2lm2 Homo sapiens Eukaryo. plasma 1 4 29.2 ± 1.6 14 ± 2 -48.8
2.1.01.01. Snake phospholipase A2, group I, acidic 1 1gp7 Ophiophagus hannah Secreted 1 0 4.6 ± 1.0 84 ± 12 -5.8
2.4.34.01. Ice-structuring protein RD1 1ucs Lycodichthys dearborni Secreted 1 0 2.2 ± 1.0 67 ± 9 -5.5
2.1.20.01. Osteocalcin 4mzz Bos taurus Secreted 1 0 1.8 ± 1.1 43 ± 8 -3.0
1.1.01.01. Archaerhodopsin-1 1uaz Halobacterium sp. Archaebac. 1 7 31.8 ± 1.3 9 ± 2 -65.3
3.1.02.01. Peptide 171-197 of parathyroid hormone receptor 1bl1 Homo sapiens Eukaryo. plasma 1 1 20.8 ± 1.2 19 ± 4 -11.5
2.4.07.01. Sorting nexin-5 3hpc Rattus norvegicus Endosome 1 0 0.0 ± 2.1 90 ± 8 -2.4
2.2.41.01. Pelovaterin 2jr3 Pelodiscus sinensis (Chinese softshell turtle) Secreted 1 0 3.2 ± 2.3 58 ± 5 -3.5
3.1.07.02. Juxtamembrane peptide (684-719) of protein gp41 2kzq Hepatitis C virus Endosome 1 0 4.3 ± 3.3 88 ± 0 -9.9
3.4.02.05. Lichenicidin VK21 A1 2ktn Bacillus licheniformis Secreted 1 0 7.0 ± 1.5 77 ± 13 -5.9
1.1.02.07. Bacteriochlorophyll c-binding protein 2k37 Chlorobium tepidum Bact. Gram-neg inner 1 0 5.8 ± 0.2 87 ± 2 -17.8
2.1.01.01. Phospholipase A2 homolog, taipoxin beta chain 3vbz Oxyuranus scutellatus scutellatus Secreted 1 0 2.8 ± 0.7 87 ± 2 -7.7
2.3.06.04. Palmitoyl-protein thioesterase 1 3gro Homo sapiens Lysosome 1 0 3.6 ± 0.1 55 ± 3 -6.8
1.2.12.01. Fimbrial protein 3sok Dichelobacter nodosus (Bacteroides nodosus) Bact. Gram-neg inner 1 1 29.8 ± 3.9 18 ± 5 -25.0
1.2.32.01. Cytochrome P450 2C5 1nr6 Oryctolagus cuniculus Endoplasm. reticulum 1 0 10.6 ± 1.0 54 ± 18 -9.1
2.1.01.01. Snake phospholipase A2, group II, hypotensive 1umv Bothrops jararacussu Secreted 1 0 5.1 ± 0.7 87 ± 4 -8.6
3.1.20.01. Conotoxin Ar1446 2m61 Conus araneosus Secreted 1 0 1.8 ± 0.8 82 ± 6 -4.0
2.2.03.01. Plasmepsin IV 1qs8 Plasmodium vivax Vacuole 1 0 9.1 ± 1.5 75 ± 5 -8.9
3.4.04.02. Surfactin 2npv Bacillus subtilis Secreted 1 0 11.3 ± 2.1 55 ± 13 -11.3
1.1.01.02. C-X-C chemokine receptor type 1 2lnl Homo sapiens Eukaryo. plasma 1 7 30.2 ± 0.9 19 ± 6 -54.4
1.2.38.01. Penicillin-binding protein 2 2olv Staphylococcus aureus Bact. Gram-pos plas. 1 0 3.7 ± 2.0 58 ± 8 -7.3
3.2.01.08. Lactoferricin B, peptide 38-49 1y58 Bos taurus Secreted 1 0 2.9 ± 1.4 86 ± 18 -3.7
3.1.28.06. Magainin analogue, MSI-594 2k98 Designed proteins Undefined 1 0 3.2 ± 0.2 86 ± 2 -8.9
2.3.16.10. Tetraacyldisaccharide 4-kinase, complex with ADP/ATP 4ehy Aquifex aeolicus Bact. Gram-neg inner 1 0 7.9 ± 0.9 71 ± 4 -12.1
2.1.18.01. Annexin IV 2zhj Rattus norvegicus Eukaryo. plasma 1 0 4.1 ± 1.0 80 ± 1 -7.6
2.2.24.01. Vitelline membrane outer protein-I 1vmo Gallus gallus Secreted 1 0 3.0 ± 2.0 51 ± 12 -5.3
2.2.12.01. Niemann-Pick type C2 protein 3web Camponotus japonicus Secreted 1 0 5.4 ± 0.3 73 ± 4 -7.6
1.2.12.02. Archaeal flagellin, single helix 3j1r Ignicoccus hospitalis Archaebac. 1 1 33.4 ± 4.4 22 ± 3 -29.6
1.1.01.02. Rhodopsin, inactive, complex with inverse agonist, 11-cis retinal 1gzm Bos taurus Eukaryo. plasma 1 7 32.2 ± 1.5 11 ± 1 -75.6
1.1.01.04. Smoothened homolog, monomer, structure 4 5l7i Homo sapiens Eukaryo. plasma 1 7 32.4 ± 1.4 10 ± 1 -58.7
2.2.34.02. Kappa-sparatoxin-Hv1b 1emx Heteropoda venatoria (Brown huntsman spider) Secreted 1 0 3.4 ± 0.9 57 ± 8 -4.8
1.1.01.02. C-C chemokine receptor type 5 4mbs Homo sapiens Eukaryo. plasma 1 7 34.4 ± 1.5 0 ± 0 -88.8
2.1.26.01. Colicin-E1 2i88 Escherichia coli Secreted 1 0 1.1 ± 3.3 58 ± 37 -1.7
3.1.07.06. NS2 protease, segment 836-868 of polyprotein 2kwt Hepatitis C virus Endoplasm. reticulum 1 0 9.5 ± 3.6 81 ± 3 -15.7
2.4.16.01. Toxin VII 1npi Tityus serrulatus Secreted 1 0 4.6 ± 1.5 52 ± 16 -6.7
2.2.34.06. Ginsentide 2ml7 Panax ginseng Secreted 1 0 7.6 ± 1.1 54 ± 8 -7.7
2.1.10.01. Glycolipid transfer protein, structure 1 1tfj Bos taurus Eukaryo. plasma 1 0 3.9 ± 1.0 90 ± 5 -8.3
1.1.01.02. Cannabinoid receptor 1, structure 1 5tgz Homo sapiens Eukaryo. plasma 1 7 34.4 ± 1.2 12 ± 0 -71.6
3.1.13.01. Islet amyloid polypeptide, peptide 38-74 2kj7 Rattus norvegicus Secreted 1 0 3.9 ± 4.3 90 ± 4 -4.2
1.3.20.01. Ferric hydroxamate uptake receptor FhuA, complex with TonB 2grx Escherichia coli Bact. Gram-neg outer 1 22 24.6 ± 1.1 3 ± 0 -77.2
2.1.60.02. Potassium channel blocking domain of matrix metalloproteinase-23 2k72 Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 2.3 77 ± 22 -4.4
1.1.25.05. Proton-dependent oligopeptide transporter, conformation 3 4ikx Geobacillus kaustophilus Bact. Gram-pos plas. 1 14 31.0 ± 1.0 10 ± 0 -115.9
2.3.06.19. PHB depolymerase PhaZ7, structure 1 2x5x Pseudomonas lemoignei Secreted 1 0 4.1 ± 3.0 54 ± 41 -5.6
3.2.10.01. PawS derived peptide 6 2lwv Designed proteins Undefined 1 0 6.8 ± 1.1 69 ± 16 -7.3
2.2.20.01. Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 3nsu Saccharomyces cerevisiae Eukaryo. plasma 1 0 0.8 ± 1.5 57 ± 12 -4.0
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 3 2ear Oryctolagus cuniculus Endoplasm. reticulum 1 10 30.0 ± 1.2 19 ± 1 -58.4
2.2.40.01. Neurotoxin III 1ans Anemonia sulcata Secreted 1 0 3.3 ± 1.4 50 ± 15 -4.7
2.3.06.06. Lipase 4l3w Rhizopus chinensis Secreted 1 0 3.2 ± 0.7 31 ± 2 -6.5
2.3.10.01. Peptidoglycan biosynthesis glycosyltransferase MurG, conformation 1 1nlm Escherichia coli Bact. Gram-neg inner 1 0 4.8 ± 1.1 50 ± 7 -7.5
2.2.20.01. Rac-beta serine/threonine protein kinase 1p6s Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 83 ± 11 -5.7
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, mutant 2 2m5f Zaire ebolavirus Viral 1 0 5.7 ± 1.7 29 ± 30 -5.2
2.3.01.04. Hyaluronidase 1fcq Apis mellifera Secreted 1 0 1.9 ± 2.7 36 ± 13 -3.7
1.3.11.01. Hemoglobin-binding protease Hbp autotransporter 3aeh Escherichia coli Bact. Gram-neg outer 1 12 25.2 ± 1.1 4 ± 0 -41.9
1.2.30.01. Potassium voltage-gated channel subfamily E member 2 2m0q Homo sapiens Eukaryo. plasma 1 1 31.8 ± 3.9 34 ± 5 -31.8
3.1.13.01. Calcitonin 2jxz Homo sapiens Secreted 1 0 5.5 ± 1.1 72 ± 6 -11.5
3.1.29.01. Retro KR-12 2nal Designed proteins Undefined 1 0 3.7 ± 0.5 83 ± 5 -6.1
1.1.87.01. Phosphatidylglycerophosphatase 5jwy Escherichia coli Bact. Gram-neg inner 1 6 30.8 ± 0.0 16 ± 2 -38.8
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform 1e7u Sus scrofa Eukaryo. plasma 1 0 2.5 ± 0.9 85 ± 3 -4.7
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 3 4j14 Homo sapiens Endoplasm. reticulum 1 0 3.4 ± 1.4 35 ± 19 -4.0
3.1.15.01. Sakacin P 1ohm Lactobacillus sake Secreted 1 0 1.8 ± 1.1 90 ± 11 -4.4
3.1.11.06. Parathyroid hormone-related peptide, structure 2 3ffd Homo sapiens Secreted 1 0 2.2 ± 1.5 89 ± 3 -5.1
2.1.37.01. Erythrocyte membrane protein 1 2xu0 Plasmodium falciparum Eukaryo. plasma 1 0 3.3 ± 6.0 75 ± 45 -3.2
3.1.02.02. TM peptide (1567-1594) of voltage-gated sodium channel Nav1.4 5jr0 Rattus norvegicus Eukaryo. plasma 1 1 30.8 ± 3.2 39 ± 2 -26.2
1.2.43.01. Envelope glycoprotein, Zika virus, structure 4 5lbv Zika virus Viral 1 0 5.7 ± 2.9 31 ± 6 -5.2
1.2.55.01. Neutral ceramidase, structure 1 2zws Pseudomonas aeruginosa Secreted 1 0 3.1 ± 2.4 77 ± 3 -8.1
1.3.19.01. Glycine-glutamate dipeptide porin OpdP 3syb Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.6 ± 0.9 8 ± 0 -62.0
2.3.16.06. ADP-ribosylation factor 1 (ARF1) 2k5u Saccharomyces cerevisiae Golgi 1 0 2.9 ± 1.6 24 ± 18 -5.5
2.4.16.02. Defensin 2nz3 Anopheles gambiae (African malaria mosquito) Secreted 1 0 6.7 ± 1.3 84 ± 10 -7.4
3.2.06.01. Plasmatocyte-spreading peptide PSP1 1b5n Pseudoplusia includens Secreted 1 0 3.1 ± 1.2 87 ± 16 -3.7
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 2 5iqw Pseudomonas aeruginosa Secreted 1 0 1.5 ± 0.2 24 ± 5 -4.8
1.2.54.01. Dihydroorotate dehydrogenase 3i65 Plasmodium falciparum Mitochon. inner 1 0 5.1 ± 1.0 47 ± 6 -13.6
1.3.22.01. VDAC-2 channel 4bum Danio rerio Mitochon. outer 1 19 23.4 ± 0.9 4 ± 0 -47.7
2.2.46.01. Low molecular mass 30 kDa lipoprotein 19G1 4iy8 Bombyx mori Secreted 1 0 4.3 ± 1.2 31 ± 8 -4.2
1.3.27.01. Capsule assembly protein Wzi 2ynk Escherichia coli Bact. Gram-neg outer 1 18 23.8 ± 1.3 6 ± 1 -58.2
2.2.34.05. Tachystatin-B2 2dcw Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 3.4 ± 0.8 2 ± 6 -10.1
1.2.01.01. Receptor tyrosine-protein kinase erbB-2 1n8y Rattus norvegicus Eukaryo. plasma 1 0 3.4 ± 3.0 53 ± 5 -4.2
2.2.06.01. Apolipoprotein D 2hzq Homo sapiens Secreted 1 0 4.5 ± 0.9 69 ± 5 -7.8
3.1.29.01. KR-12 from cathelicidin LL-37 2na3 Homo sapiens Secreted 1 0 3.7 ± 0.7 84 ± 8 -8.3
2.3.06.05. Thermostable Esterase 3doh Thermotoga maritima Bact. Gram-neg inner 1 0 4.0 ± 2.0 84 ± 13 -4.4
1.1.01.02. Melanocortin-4 receptor model (inactive state) with antagonist AGRP 2iqv Homo sapiens Eukaryo. plasma 1 7 31.9 ± 1.1 19 ± 0 -49.1
1.1.34.01. Mitochondrial ADP-ATP carrier, with carboxyatractyloside 2c3e Bos taurus Mitochon. inner 1 6 30.0 ± 1.0 4 ± 2 -44.0
2.3.01.02. Beta-glycosidase 1vff Pyrococcus horikoshii Archaebac. 1 0 3.9 ± 1.6 39 ± 10 -9.7
1.1.09.01. Plasma membrane ATPase 2, E1-ATP state 5ksd Arabidopsis thaliana Eukaryo. plasma 1 10 30.8 ± 1.2 4 ± 1 -59.3
2.1.09.01. Major allergen I 1puo Felis catus Secreted 1 0 3.7 ± 0.8 58 ± 6 -7.8
2.4.51.01. Heme acquisition protein HasA 3ell Pseudomonas aeruginosa Secreted 1 0 3.3 ± 0.4 18 ± 8 -5.5
1.1.58.01. Site-2 protease (S2P) metalloprotease 3b4r Methanococcus jannaschii Archaebac. 1 6 29.9 ± 1.4 23 ± 0 -65.0
1.3.19.02. Alginate export protein, AlgE, conformation 5 4xnl Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 25.2 ± 1.1 3 ± 0 -73.6
1.1.25.06. Glucose transporter GLUT3/SLC2A3, outward-occluded 4zw9 Homo sapiens Eukaryo. plasma 1 12 32.8 ± 1.4 6 ± 1 -95.1
2.4.04.01. Inositol polyphosphate 5-phosphatase OCRL-1 4cmn Homo sapiens Endosome 1 0 6.7 ± 1.6 83 ± 2 -9.2
3.1.29.01. Ovispirin-1 1hu5 Ovis aries Secreted 1 0 5.7 ± 0.5 81 ± 1 -9.2
3.1.04.04. Peptide of huntigtin, 1-17 2ld2 Homo sapiens Eukaryo. plasma 1 0 4.2 ± 0.6 90 ± 4 -9.3
2.3.19.01. Cytotoxin L 2vkh Clostridium sordellii Secreted 1 0 1.4 ± 2.0 51 ± 17 -4.5
2.1.01.03. Prokaryotic phospholipase A2 1kp4 Streptomyces violaceoruber Secreted 1 0 2.4 ± 1.3 42 ± 13 -5.6
2.1.44.01. Sublancin-168 2mij Bacillus subtilis Secreted 1 0 4.0 ± 5.0 83 ± 0 -4.2
1.3.20.01. Hemophore receptor HasR, structure 2 5c58 Serratia marcescens Bact. Gram-neg outer 1 22 24.8 ± 1.2 2 ± 0 -68.0
1.1.01.02. Orexin receptor type 1 4zjc Homo sapiens Eukaryo. plasma 1 7 31.6 ± 1.5 4 ± 1 -67.5
2.1.29.04. Apolipoprotein C-II 1i5j Homo sapiens Secreted 1 0 4.4 ± 2.3 42 ± 3 -9.9
1.1.01.02. Rhodopsin, inactive, structure 3 1u19 Bos taurus Eukaryo. plasma 1 7 31.2 ± 1.5 12 ± 1 -71.9
1.1.39.01. Riboflavin transporter RibU 3p5n Staphylococcus aureus Bact. Gram-pos plas. 1 6 30.6 ± 1.4 6 ± 4 -53.5
2.2.35.01. Anthrolysin O 3cqf Bacillus anthracis Secreted 1 0 2.8 ± 1.0 75 ± 1 -5.8
1.1.75.01. Sec-independent protein translocase TatC 4b4a Aquifex aeolicus Bact. Gram-neg inner 1 6 30.4 ± 1.2 17 ± 0 -51.7
1.1.01.02. Beta-1 adrenergic receptor, inactive, complex with agonist 2y02 Meleagris gallopavo Eukaryo. plasma 1 7 31.4 ± 1.3 2 ± 0 -76.9
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3ld6 Homo sapiens Endoplasm. reticulum 1 0 8.9 ± 0.6 57 ± 2 -16.8
2.2.34.08. Agouti-related protein 1mr0 Homo sapiens Secreted 1 0 3.1 ± 2.0 37 ± 18 -5.6
2.2.34.02. S64 4b2v Sicarius dolichocephalus Secreted 1 0 2.5 ± 0.5 71 ± 2 -4.3
2.2.27.01. C1 domain of protein kinase C delta 1ptr Mus musculus Eukaryo. plasma 1 0 6.6 ± 1.5 19 ± 8 -5.9
2.3.08.02. Cytosolic phospholipase A2 delta, structure 2 5iz5 Homo sapiens Vesicle 1 0 1.0 ± 0.0 77 ± 0 -4.1
2.2.34.02. Beta-hexatoxin-Mg1a 2gx1 Macrothele gigas (Spider) Secreted 1 0 5.6 ± 2.6 51 ± 9 -4.6
1.3.20.01. Pyoverdine Outer Membrane Receptor FpvA 2iah Pseudomonas aeruginosa Bact. Gram-neg outer 1 22 24.0 ± 0.5 8 ± 0 -79.7
1.2.17.01. Syntaxin 1A, pre-fusion structure in micelles 2m8r Rattus norvegicus Eukaryo. plasma 1 2 20.8 ± 0.5 8 ± 5 -20.5
2.2.34.11. Violacin 1 2fqa Viola odorata Secreted 1 0 2.4 ± 3.4 70 ± 46 -4.0
2.4.05.01. Sterol carrier protein 2-like 2 2qzt Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 1.0 ± 2.0 45 ± 12 -3.0
2.4.34.01. Type III antifreeze protein nfeAFP11 2lx2 Zoarces elongatus Secreted 1 0 5.3 ± 1.0 53 ± 5 -7.0
2.1.08.01. Cytochrome c551 1cor Pseudomonas stutzeri Bact. Gram-neg inner 1 0 2.6 ± 1.1 73 ± 12 -6.1
2.2.11.01. Synaptotagmin-4 1ugk Homo sapiens Eukaryo. plasma 1 0 2.5 ± 1.7 34 ± 11 -3.5
2.4.50.01. Matrix protein, New Jersey virus 2w2r Vesicular stomatitis virus Viral 1 0 4.1 ± 0.1 57 ± 1 -10.4
1.3.19.01. Outer membrane porin OprD 2odj Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.0 ± 0.8 8 ± 0 -63.1
2.2.27.01. RAS guanyl-releasing protein 1 4l9m Homo sapiens Eukaryo. plasma 1 0 5.3 ± 1.3 24 ± 3 -7.8
2.2.06.01. Allergen Bos d 2 1bj7 Bos taurus Secreted 1 0 3.1 ± 1.3 50 ± 6 -3.5
1.2.04.01. Integrin beta-3, 742-788, 747pY, in water 2ljf Homo sapiens Eukaryo. plasma 1 0 0.6 ± 1.6 62 ± 14 -1.8
1.1.09.01. Calcium ATPase, E1-2Ca state, conformation 4 2c9m Oryctolagus cuniculus Endoplasm. reticulum 1 10 29.8 ± 1.2 27 ± 1 -54.3
2.3.06.06. Triacylglycerol lipase, open (active) state 4tgl Rhizomucor miehei Secreted 1 0 8.8 ± 0.9 64 ± 11 -18.2
2.2.35.01. Pneumolysin, structure 3 5cr8 Streptococcus pneumoniae Secreted 1 0 4.7 ± 1.2 37 ± 6 -9.3
2.2.06.02. Adipocyte lipid-binding protein 1a18 Mus musculus Eukaryo. plasma 1 0 3.7 ± 0.8 47 ± 7 -7.4
2.1.64.01. Envelope glycoprotein, ligand-binding domain 1 5e7x Talaromyces marneffei Eukaryo. plasma 1 0 2.7 ± 2.2 55 ± 13 -4.4
1.2.43.01. Envelope glycoprotein, Dengue virus type 4 3uaj Dengue virus Viral 1 0 5.6 ± 2.6 17 ± 7 -5.4
2.4.29.01. Enterotoxin type A 1dyq Staphylococcus aureus Secreted 1 0 3.9 ± 0.5 82 ± 6 -6.8
1.3.21.01. Outer membrane usher protein FimD 3ohn Escherichia coli Bact. Gram-neg outer 1 24 21.2 ± 1.1 5 ± 0 -45.4
2.4.16.01. Alpha-insect toxin Lqq3 1lqq Leiurus quinquestriatus quinquestriatus Secreted 1 0 0.8 ± 1.0 80 ± 6 -3.3
2.4.15.01. Protein Nef (HIV HV1LW) 2nef Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 6.3 ± 1.4 73 ± 3 -7.9
1.2.53.01. Squalene synthase, conformation 4 3wek Homo sapiens Endoplasm. reticulum 1 0 0.4 ± 2.5 87 ± 15 -3.2
3.4.08.01. Neurotensin 2oyv Homo sapiens Secreted 1 0 7.3 ± 2.6 67 ± 17 -5.3
2.2.34.06. Inhibitor cystine knot peptide MCh-1 2m2q Momordica charantia Secreted 1 0 6.9 ± 0.7 74 ± 7 -6.3
2.4.06.01. StAR-related lipid transfer protein 13 2pso Homo sapiens Eukaryo. plasma 1 0 3.1 ± 4.0 77 ± 27 -4.6
2.4.04.01. Beta-hemolysin 3i48 Staphylococcus aureus Secreted 1 0 2.8 ± 0.8 57 ± 5 -5.1
1.2.44.01. Amyloid beta A4 protein (peptide 672-711), in water 2lfm Homo sapiens Eukaryo. plasma 1 0 5.3 ± 0.5 87 ± 4 -8.6
1.2.39.03. Disintegrin and metalloproteinase domain-containing protein 10 2ao7 Bos taurus Golgi 1 0 3.1 ± 1.4 81 ± 6 -5.7
2.4.16.04. Defensin NaD1 1mr4 Nicotiana tabacum Secreted 1 0 4.2 ± 1.8 59 ± 11 -3.0
3.4.04.01. Tsushimycin 1w3m Streptomyces pseudogriseolus Secreted 1 0 9.5 ± 2.1 54 ± 24 -8.6
2.2.20.01. PH domain of muscle M-line assembly protein unc-89 1fho Caenorhabditis elegans Eukaryo. plasma 1 0 2.3 ± 1.2 25 ± 14 -4.3
2.3.21.01. Protein-tyrosine phosphatase, mitochondrial 1 3rgq Mus musculus Mitochon. inner 1 0 1.7 ± 0.7 54 ± 7 -4.9
2.3.06.02. Antigen 85a 1sfr Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 2.8 ± 0.8 27 ± 9 -7.5
2.2.11.01. Perforin 3w57 Psetta maxima Secreted 1 0 3.8 ± 1.2 38 ± 5 -7.8
1.3.17.02. Translocation and assembly module TamA 4c00 Escherichia coli Bact. Gram-neg outer 1 16 23.4 ± 1.3 7 ± 1 -52.2
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens Endosome 1 0 2.4 ± 1.6 88 ± 12 -4.6
3.2.01.03. Androctonin 1cz6 Androctonus australis (Sahara scorpion) Secreted 1 0 1.5 ± 2.8 89 ± 16 -3.2
1.1.99.01. Prolipoprotein diacylglyceryl transferase 5azb Escherichia coli Bact. Gram-neg inner 1 7 30.2 ± 1.5 8 ± 1 -68.8
2.4.31.01. Ficolin-1 2wnp Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.8 65 ± 2 -5.3
2.2.05.01. Plastocyanin 1b3i Prochlorothrix hollandica Thylakoid 1 0 2.8 ± 1.4 43 ± 18 -4.4
2.2.41.01. Beta-defensin 2 1fd3 Homo sapiens Secreted 1 0 5.2 ± 1.2 80 ± 12 -9.1
2.1.19.01. Ribosome-inactivating protein luffin P1 2l37 Luffa aegyptiaca Secreted 1 0 1.3 ± 0.9 80 ± 7 -3.3
1.1.52.01. Oligosaccharyltransferase PglB 3rce Campylobacter lari Bact. Gram-neg inner 1 13 28.8 ± 0.9 8 ± 0 -89.6
1.2.03.04. Leukocyte immunoglobulin-like receptor subfamily B member 4 3p2t Homo sapiens Eukaryo. plasma 1 0 1.7 ± 0.4 84 ± 5 -5.9
2.2.04.01. 9-cis-epoxycarotenoid dioxygenase 1, chloroplastic 3npe Zea mays Thylakoid 1 0 6.0 ± 0.1 30 ± 5 -11.1
3.4.02.04. Cinnamycin 2dde Streptoverticillium griseoverticillatum Secreted 1 0 3.6 ± 1.9 30 ± 24 -5.4
2.4.06.01. STAR-related lipid transfer protein from bacteria 3qsz Xanthomonas axonopodis Bact. Gram-neg inner 1 0 3.7 ± 1.4 58 ± 15 -3.0
1.1.09.01. Calcium ATPase, E1P-ADP state 2zbd Oryctolagus cuniculus Endoplasm. reticulum 1 10 31.8 ± 1.4 22 ± 2 -70.6
2.1.01.01. Snake phospholipase A2, group II 1vap Agkistridon piscivorus Secreted 1 0 5.1 ± 0.6 88 ± 5 -10.3
2.2.34.11. Kalata-B12 2kvx Oldenlandia affinis Secreted 1 0 4.4 ± 1.2 68 ± 27 -5.6
1.3.19.02. Alginate export protein, AlgE, conformation 6 5d5d Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.4 ± 1.2 4 ± 1 -67.1
1.1.25.06. Glucose transporter GLUT5, inward-open 4yb9 Bos taurus Eukaryo. plasma 1 12 31.8 ± 1.0 6 ± 0 -89.9
3.1.07.01. Fusion peptide (1185-1201) of spike glycoprotein 2run Human SARS coronavirus Endosome 1 0 6.8 ± 4.0 74 ± 7 -10.7
3.1.21.01. Cecropin B analogue 2igr Hyalophora cecropia (Cecropia moth) Secreted 1 0 5.1 ± 3.6 87 ± 0 -11.3
1.2.44.01. Amyloid beta A4 protein, peptide 686-726 2llm Homo sapiens Eukaryo. plasma 1 1 32.8 ± 2.2 30 ± 0 -30.8
2.3.06.08. Pancreatic lipase-related protein 1 2ppl Homo sapiens Secreted 1 0 7.1 ± 0.9 79 ± 6 -10.2
3.2.09.01. Octreotide 1soc Designed proteins Undefined 1 0 8.9 ± 1.8 77 ± 21 -7.7
1.1.26.05. Glutamate/gamma-aminobutyrate antiporter 4dji Escherichia coli Bact. Gram-neg inner 1 12 30.0 ± 1.1 10 ± 1 -98.9
2.3.02.01. Phospholipase C-beta isoform 2 2zkm Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.9 38 ± 12 -3.6
1.2.50.01. Equinatoxin II 1iaz Actinia equina Secreted 1 0 3.0 ± 1.2 44 ± 9 -5.1
3.2.05.02. Astexin-1, structure 1 2lti Asticcacaulis excentricus Secreted 1 0 2.4 ± 1.0 85 ± 9 -3.6
2.2.34.01. Omega-conotoxin GVIA 2cco Conus geographus (Geography cone) Secreted 1 0 4.4 ± 0.9 62 ± 7 -3.1
1.3.01.01. Outer membrane protein A (OMPA), disordered loops 1qjp Escherichia coli Bact. Gram-neg outer 1 8 25.4 ± 1.5 11 ± 1 -29.5
1.1.01.03. Corticotropin-releasing factor receptor 1, structure 1 4k5y Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.1 16 ± 3 -71.4
2.1.01.01. Myotoxin II 1y4l Bothrops asper Secreted 1 0 2.8 ± 0.8 76 ± 7 -10.3
2.2.43.01. Hypothetical protein SpyM3_0169 1pg6 Streptococcus pyogenes Undefined 1 0 7.6 ± 1.5 57 ± 6 -7.2
1.1.44.01. Disulfide bond formation protein B, conformation 2 2ltq Escherichia coli Bact. Gram-neg inner 1 4 28.4 ± 1.5 26 ± 0 -36.5
1.2.25.01. Phospholamban, monomer 1n7l Oryctolagus cuniculus Endoplasm. reticulum 1 1 29.8 ± 3.6 34 ± 12 -32.3
2.2.34.02. Phrixotoxin 1 1v7f Paraphysa scrofa Secreted 1 0 4.1 ± 1.2 90 ± 16 -6.8
2.3.06.07. Lipase 4gw3 Proteus mirabilis Secreted 1 0 3.7 ± 0.9 43 ± 7 -5.1
3.1.20.01. Alpha-conotoxin EI 1k64 Conus ermineus Secreted 1 0 3.6 ± 1.4 78 ± 19 -3.3
1.2.04.01. Integrin alpha-L, transmembrane helix (1082-1128) 2m3e Homo sapiens Eukaryo. plasma 1 1 29.8 ± 5.6 30 ± 17 -25.9
3.2.01.06. Theta-defensin 1 (RTD-1) 1hvz Macaca mulatta Secreted 1 0 0.8 ± 1.0 89 ± 4 -2.9
1.1.68.01. Transmembrane protein 141 2lor Homo sapiens Undefined 1 2 24.4 ± 4.0 21 ± 0 -22.2
1.1.25.07. Nitrate/nitrite exchanger NarK, partially occluded state 4jr9 Escherichia coli Bact. Gram-neg inner 1 12 29.6 ± 1.0 8 ± 0 -86.2
2.4.07.01. Bud emergence protein 1 2v6v Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.1 ± 1.2 75 ± 6 -5.1
1.2.32.01. Cytochrome P450 2B6, conformation 2 3ua5 Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 1.1 55 ± 3 -12.9
2.2.41.01. Beta-defensin 7 1e4t Mus musculus Secreted 1 0 3.6 ± 1.4 13 ± 19 -5.2
3.4.10.01. Methanobactin 4oz7 Methylosinus sporium Secreted 1 0 2.5 ± 1.4 86 ± 15 -4.5
2.2.04.01. Lignostilbene-alpha,beta-dioxygenase (retinal-forming oxygenase) 2biw Synechocystis sp. Bact. Gram-neg inner 1 0 6.1 ± 0.9 39 ± 9 -12.9
1.1.01.01. Proton-pumping rhodopsin-2 from algae 3am6 Acetabularia acetabulum Eukaryo. plasma 1 7 31.2 ± 1.6 10 ± 1 -65.4
1.1.01.02. 5-hydroxytryptamine receptor 2B, structure 2, with LSD 5tvn Homo sapiens Eukaryo. plasma 1 7 33.0 ± 2.0 18 ± 2 -68.3
2.2.39.01. Beta-cardiotoxin 3plc Ophiophagus hannah Secreted 1 0 4.6 ± 1.1 73 ± 4 -6.7
1.3.20.01. Hemophore receptor HasR, structure 1 3csl Serratia marcescens Bact. Gram-neg outer 1 22 25.4 ± 1.3 4 ± 5 -72.2
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 1 2gek Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 3.4 ± 2.6 85 ± 5 -5.7
3.2.01.09. Peptide PG-989 2n7n Designed proteins Undefined 1 0 6.1 ± 1.4 83 ± 7 -5.5
2.1.02.01. Linoleate 9/13-lipoxygenase 4g32 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 5.8 ± 0.9 33 ± 2 -10.7
3.1.02.02. Potassium voltage-gated channel protein Shaker, peptide 378-397 1ho2 Drosophila melanogaster Eukaryo. plasma 1 0 3.9 ± 1.2 88 ± 16 -7.5
1.2.32.01. Cytochrome P450 2C19 4gqs Homo sapiens Endoplasm. reticulum 1 0 6.4 ± 2.1 71 ± 5 -9.5
2.3.06.07. Lipase L1 1ku0 Bacillus stearothermophilus Secreted 1 0 4.0 ± 0.6 23 ± 9 -8.9
2.1.25.05. Aureocin A53 2n8o Staphylococcus aureus Secreted 1 0 0.8 ± 0.4 78 ± 6 -2.6
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 5 4utc Dengue virus Viral 1 0 6.3 ± 2.4 13 ± 7 -4.2
2.2.07.02. Factor H binding protein 1ys5 Neisseria meningitidis Bact. Gram-neg outer 1 0 3.5 ± 2.6 84 ± 5 -5.6
2.2.20.01. Rho guanine nucleotide exchange factor 9, conformation 1 4mt7 Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 2.6 52 ± 14 -3.9
2.4.16.04. Defensin-like protein 195 1jxc Arabidopsis thaliana Secreted 1 0 4.0 ± 1.5 21 ± 20 -3.9
3.1.02.01. Second intracellular loop (118-149) of alpha-2A adrenergic receptor 1hod Homo sapiens Eukaryo. plasma 1 0 3.9 ± 4.1 75 ± 3 -7.2
1.2.32.01. Cytochrome P450 21-hydroxylase, 21A2 4y8w Homo sapiens Endoplasm. reticulum 1 0 7.2 ± 0.7 59 ± 4 -13.4
3.1.20.01. alpha-conotoxin PNIB 1akg Conus pennaceus Secreted 1 0 4.2 ± 1.4 42 ± 19 -5.9
1.1.30.01. Membrane protein insertase YidC, periplasmic domain 3blc Escherichia coli Bact. Gram-neg inner 1 0 6.6 ± 0.5 40 ± 11 -7.0
1.2.54.01. Dihydroorotate dehydrogenase 1uum Rattus norvegicus Mitochon. inner 1 0 6.9 ± 0.4 50 ± 6 -6.3
1.3.14.01. Fatty Acid Transporter FadL, F3E, open channel 3pgu Escherichia coli Bact. Gram-neg outer 1 14 25.2 ± 1.5 1 ± 1 -51.5
3.1.07.10. Structural peptide 1 of bursal disease virus 2imu Avian infectious bursal disease virus Eukaryo. plasma 1 0 11.6 ± 4.0 76 ± 5 -17.5
2.4.25.01. N-alpha-acetyltransferase 60, structure 2 5hh0 Homo sapiens Golgi 1 0 5.2 ± 0.0 46 ± 1 -10.7
3.1.28.04. Gaegurin-4 2g9l Glandirana rugosa (Japanese wrinkled frog) Secreted 1 0 8.9 ± 4.0 71 ± 3 -9.6
1.1.25.03. Multidrug transporter MdfA 4zp0 Escherichia coli Bact. Gram-neg inner 1 12 29.8 ± 1.3 10 ± 0 -77.2
1.1.70.01. CAAX prenyl protease 1 homolog, structure 1 5syt Homo sapiens Endoplasm. reticulum 1 7 31.4 ± 1.4 15 ± 0 -79.9
2.3.06.06. Triacylglycerol lipase, closed (inactive) state 1dt5 Humicola lanuginosa Secreted 1 0 5.1 ± 0.9 79 ± 13 -5.9
2.4.34.01. Ice-structuring protein 4ur4 Zoarces viviparus Secreted 1 0 3.2 ± 4.1 68 ± 2 -5.8
2.2.11.01. Rabphilin-3A, C2A domain 2chd Rattus norvegicus Eukaryo. plasma 1 0 2.9 ± 1.6 57 ± 19 -2.7
2.2.34.11. Circulin A 1bh4 Chassalia parviflora Secreted 1 0 3.9 ± 1.2 60 ± 18 -6.6
2.1.20.01. Coagulation factor X, GLA domain 1iod Bos taurus Secreted 1 0 3.3 ± 0.9 25 ± 15 -5.2
3.1.02.01. Third extracellular loop of cholecystokinin A receptor 1hzn Homo sapiens Eukaryo. plasma 1 0 3.4 ± 0.9 81 ± 2 -10.3
2.4.07.01. Sorting nexin-23 (Kinesin-like protein KIF16B) 2v14 Homo sapiens Endosome 1 0 3.3 ± 3.0 72 ± 14 -5.4
3.1.28.04. Ranatuerin-2csa 2k10 Rana temporaria Secreted 1 0 10.4 ± 1.2 74 ± 5 -14.3
1.1.78.01. Lipoprotein signal peptidase 5dir Pseudomonas aeruginosa Bact. Gram-neg inner 1 4 29.8 ± 1.9 13 ± 0 -42.7
1.3.17.01. Filamentous hemagglutinin transporter FhaC, structure 2 4ql0 Bordetella pertussis Bact. Gram-neg outer 1 16 23.2 ± 0.9 10 ± 0 -62.7
3.1.04.08. Truncated superoxide dismutase 1 2mp3 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 83 ± 0 -6.3
2.1.29.06. Perilipin-3 1szi Mus musculus Endosome 1 0 2.4 ± 2.3 61 ± 6 -4.1
3.1.21.04. Oxyopinin-4a 2l3i Oxyopes takobius (Lynx spider) Secreted 1 0 6.2 ± 1.2 71 ± 10 -6.8
2.3.05.03. L-amino acid deaminase 5hxw Proteus vulgaris Bact. Gram-neg inner 1 0 6.4 ± 2.1 86 ± 6 -9.0
2.3.06.10. Platelet-activating factor acetylhydrolase 3d59 Homo sapiens Secreted 1 0 5.5 ± 1.2 87 ± 10 -13.6
2.1.24.01. Saposin A (peptide 60-140) 2dob Homo sapiens Lysosome 1 0 2.0 ± 2.5 70 ± 29 -4.2
2.2.05.01. Azurin 1xb8 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 2.7 ± 0.6 47 ± 4 -5.2
2.2.11.01. Synaptotagmin-1, C2A domain (Calcium free) 3f00 Homo sapiens Eukaryo. plasma 1 0 1.4 ± 1.5 29 ± 18 -3.3
1.2.32.01. Cytochrome P450 2B4, closed state 1 1suo Oryctolagus cuniculus Endoplasm. reticulum 1 0 4.6 ± 1.3 57 ± 4 -14.2
2.1.01.01. Myotoxin 1god Bothrops godmani Secreted 1 0 3.0 ± 0.8 80 ± 8 -7.4
3.2.02.02. Chi-conotoxin Ar1248 2m62 Conus araneosus Secreted 1 0 1.9 ± 1.0 78 ± 12 -3.0
1.3.17.02. BamACDE subcomplex, structure 2 5d0q Escherichia coli Bact. Gram-neg outer 1 16 22.8 ± 1.1 10 ± 0 -44.9
3.1.01.05. Proteinase inhibitor, vacuolar targeting peptide (372-397) 1vtp Nicotiana alata (Winged tobacco) Vacuole 1 0 3.5 ± 1.1 87 ± 4 -4.2
2.2.39.01. Erabutoxin b 3ebx Laticauda semifasciata (Black-banded sea krait) Secreted 1 0 1.9 ± 1.4 47 ± 11 -4.3
1.2.38.01. Glycosyltransferase MtgA 3hzs Staphylococcus aureus Bact. Gram-pos plas. 1 0 7.0 ± 1.1 54 ± 9 -14.6
3.1.29.02. Indolicidin analogue (cathelicidin-4) 1qx9 Bos taurus Secreted 1 0 6.6 ± 1.9 46 ± 15 -7.7
3.1.05.07. Penetratin 1omq Designed proteins Undefined 1 0 3.2 ± 1.0 79 ± 7 -7.4
1.1.01.02. Dopamine D3 receptor 3pbl Homo sapiens Eukaryo. plasma 1 7 33.0 ± 1.8 8 ± 1 -56.6
3.1.21.03. Melittin, with organometallic fragment 2mw6 Apis mellifera Secreted 1 1 24.2 ± 2.4 6 ± 2 -11.8
2.4.16.12. Actinomycesin 2ru0 Actinomyces sp. Secreted 1 0 3.5 ± 0.7 83 ± 7 -4.1
3.1.01.03. N-terminal helix of prion-like protein doppel 1z65 Mus musculus Eukaryo. plasma 1 1 21.0 ± 6.2 8 ± 4 -13.2
1.2.03.05. Cytokine receptor common subunit beta (432-473) 2na8 Homo sapiens Eukaryo. plasma 1 1 34.0 ± 2.8 22 ± 2 -32.9
2.2.11.01. Perforin-1 3nsj Mus musculus Vesicle 1 0 3.1 ± 1.0 34 ± 11 -3.3
2.2.34.02. Beta-theraphotoxin-Cj1a 2i1t Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.2 ± 0.7 58 ± 6 -5.8
1.2.18.01. Sortase B 1rz2 Bacillus anthracis Bact. Gram-pos plas. 1 0 3.0 ± 0.6 82 ± 6 -5.8
2.2.34.11. Cycloviolacin-O14 2gj0 Viola odorata Secreted 1 0 3.6 ± 1.5 85 ± 16 -5.4
2.3.13.05. Putative peroxiredoxin Rv2238c/MT2298 1xvw Mycobacterium tuberculosis Undefined 1 0 4.6 ± 1.0 20 ± 5 -7.0
3.1.07.05. Nonstructural protein 4b, segment 1751-1780 2jxf Hepatitis C virus Endoplasm. reticulum 1 0 5.6 ± 3.6 85 ± 2 -10.6
2.4.16.01. Tx10 alpha-like toxin 1kv0 Buthus martensii Secreted 1 0 1.9 ± 1.1 83 ± 11 -4.6
3.1.13.01. Adrenomedullin 2l7s Homo sapiens Secreted 1 0 2.6 ± 0.7 90 ± 5 -6.7
3.1.12.01. Sarafotoxin-M 2ldf Atractaspis microlepidota microlepidota Secreted 1 0 2.3 ± 1.5 30 ± 35 -2.1
1.3.20.01. Outer membrane cobalamin transporter BtuB, complex with TonB 2gsk Escherichia coli Bact. Gram-neg outer 1 22 23.4 ± 0.7 5 ± 0 -77.5
2.2.14.01. C2 domain of coagulation factor VIII 4mo3 Sus scrofa Eukaryo. plasma 1 0 3.7 ± 0.6 19 ± 4 -9.7
1.1.01.01. Proteorhodopsin 4hyj Exiguobacterium sibiricum Bact. Gram-pos plas. 1 7 30.0 ± 1.6 15 ± 7 -56.8
2.3.06.14. Esterase LipA 3h2g Xanthomonas oryzae Secreted 1 0 5.1 ± 1.7 87 ± 8 -4.9
3.2.10.01. PawS derived peptide 11 2lwq Designed proteins Undefined 1 0 10.1 ± 1.4 55 ± 22 -9.5
1.2.12.01. Geopilin domain 1 protein 2m7g Geobacter sulfurreducens Bact. Gram-neg inner 1 1 29.8 ± 4.2 39 ± 8 -26.8
2.2.20.01. Rho GTPase-activating protein 27 3pp2 Homo sapiens Eukaryo. plasma 1 0 2.5 ± 2.2 72 ± 14 -3.4
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 4 3fps Oryctolagus cuniculus Endoplasm. reticulum 1 10 30.0 ± 0.9 16 ± 0 -53.5
2.3.06.16. Putative hydrolase RPA1511 4psu Rhodopseudomonas palustris Secreted 1 0 7.0 ± 1.2 47 ± 4 -13.0
1.1.25.02. Lactose permease LacY, structure 1 2cfq Escherichia coli Bact. Gram-neg inner 1 12 31.9 ± 1.1 5 ± 1 -87.9
2.2.20.01. SET binding factor 1 1v5u Mus musculus Eukaryo. plasma 1 0 4.2 ± 1.5 59 ± 10 -5.3
2.2.06.02. Retinol-binding protein 1 5h9a Homo sapiens Eukaryo. plasma 1 0 3.3 ± 0.9 59 ± 4 -5.7
2.3.01.06. Endoglycoceramidase II 2osx Rhodococcus sp. Secreted 1 0 7.9 ± 0.4 68 ± 1 -13.4
1.1.10.03. ATP-binding cassette, sub-family B, member 1, mutant 3wmg Cyanidoschyzon merolae Eukaryo. plasma 1 6 36.8 ± 0.3 10 ± 3 -65.5
3.1.13.01. Calcitonin-1 2glg Oncorhynchus keta (Chum salmon) Secreted 1 0 6.1 ± 0.8 84 ± 4 -11.7
3.1.05.03. Glycosaminoglycan-binding (KYE) peptide 2ncw Designed proteins Undefined 1 0 5.0 ± 0.4 84 ± 6 -10.1
1.2.32.01. Lanosterol 14-alpha demethylase (CYP51), with drug 4wmz Saccharomyces cerevisiae Endoplasm. reticulum 1 1 29.8 ± 0.7 39 ± 0 -36.1
3.1.21.08. Moricin 1kv4 Bombyx mori Secreted 1 0 6.1 ± 0.6 77 ± 14 -10.3
2.1.25.02. Enterocin NKR-5-3B 2mp8 Enterococcus faecium Secreted 1 0 4.9 ± 1.9 68 ± 29 -6.4
2.1.37.01. Erythrocyte membrane protein 1 variant 3c64 Plasmodium falciparum Eukaryo. plasma 1 0 5.3 ± 2.5 52 ± 3 -9.6
1.1.01.04. Smoothened homolog, monomer, structure 5 5v56 Homo sapiens Eukaryo. plasma 1 7 30.2 ± 1.8 12 ± 3 -60.3
1.2.43.01. Envelope glycoprotein, Zika virus, structure 5 5lbs Zika virus Viral 1 0 2.3 ± 2.5 62 ± 5 -4.7
2.4.32.01. Vanadium chloroperoxidase 3bb0 Curvularia inaequalis Secreted 1 0 3.8 ± 0.8 52 ± 6 -5.3
1.3.19.01. Porin OpdF 3szd Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 22.0 ± 1.6 3 ± 0 -60.3
2.4.07.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Homo sapiens Golgi 1 0 2.5 ± 1.3 56 ± 16 -4.8
2.4.16.02. Defensin 2b68 Crassostrea gigas (Pacific oyster) Secreted 1 0 5.8 ± 1.7 28 ± 20 -4.0
3.2.06.01. Paralytic peptide 1irr Bombyx mori Secreted 1 0 2.2 ± 1.9 74 ± 19 -3.3
2.4.51.01. Heme acquisition protein HasA 4xzd Yersinia pseudotuberculosis Secreted 1 0 3.5 ± 0.4 25 ± 2 -5.9
2.3.05.01. Flavoprotein-ubiquinone oxydoreductase 2gmh Sus scrofa Mitochon. inner 1 0 7.2 ± 0.8 38 ± 4 -18.5
1.1.83.01. Mitochondrial translocator protein, TSPO, model 1 2mgy Mus musculus Mitochon. outer 1 5 28.6 ± 1.6 12 ± 1 -17.9
2.1.01.01. Basic phospholipase A2 PA-11 3v9m Pseudechis australis Secreted 1 0 4.0 ± 0.5 83 ± 2 -10.1
1.3.10.01. Oligogalacturonate-specific porin KdgM 4fqe Dickeya dadantii Bact. Gram-neg outer 1 12 22.2 ± 1.5 2 ± 1 -42.1
2.3.16.07. Ras-related protein Rab-5C 4kyi Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.4 73 ± 1 -6.0
1.2.41.01. Acyl-CoA-binding protein 2cb8 Homo sapiens Peroxisome 1 0 2.7 ± 2.0 74 ± 29 -5.2
2.2.34.05. Tachystatin-B1 2dcv Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 1.8 ± 1.1 5 ± 9 -5.9
1.1.25.09. Iron-regulated transporter, outward-facing state 5ayn Bdellovibrio bacteriovorus Bact. Gram-neg inner 1 12 29.8 ± 1.8 8 ± 4 -82.9
1.1.02.06. Light-harvesting complex CP29 3pl9 Spinacia oleracea Thylakoid 1 3 29.8 ± 1.6 2 ± 2 -66.6
2.2.39.01. Cardiotoxin-A1 (cytotoxin 1) 2cdx Naja atra Secreted 1 0 2.6 ± 1.4 85 ± 17 -6.9
3.2.05.02. LP2006 5jpl Nocardiopsis alba Secreted 1 0 3.6 ± 1.7 59 ± 12 -4.2
2.3.06.04. Acyl transferase LuxD 1tht Vibrio harveyi Bact. Gram-neg inner 1 0 3.3 ± 1.3 85 ± 4 -6.1
1.1.34.01. Mitochondrial ADP-ATP carrier, conformation 1 4c9g Saccharomyces cerevisiae Mitochon. inner 1 6 31.4 ± 1.5 1 ± 1 -54.6
1.1.38.01. H+-driven MATE exporter, outward-open, straight conformation 3wbn Pyrococcus furiosus Archaebac. 1 12 31.8 ± 1.4 8 ± 0 -88.2
3.2.01.01. Arenicin-2 2jni Arenicola marina Secreted 1 0 2.1 ± 1.1 82 ± 15 -5.2
2.4.51.01. Heme acquisition protein HasA, apoprotein 1ybj Serratia marcescens Secreted 1 0 2.8 ± 2.4 33 ± 9 -3.9
1.1.26.05. Amino acid transporter ApcT, inward-facing conformation 3gia Methanococcus jannaschii Archaebac. 1 12 29.9 ± 1.4 11 ± 2 -92.1
1.3.15.02. CymA protein, conformation 1 4d51 Klebsiella oxytoca Bact. Gram-neg outer 1 14 25.0 ± 1.7 2 ± 1 -44.8
1.1.01.02. Rhodopsin, complex with arrestin 4zwj Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.1 9 ± 1 -78.7
1.2.46.01. Agnoprotein (17-52) 2mj2 JC polyomavirus Endosome 1 1 22.0 ± 2.0 25 ± 3 -15.0
2.2.34.03. Toxin Ptu1 1i26 Peirates turpis (Assassin bug) Secreted 1 0 2.5 ± 0.9 52 ± 7 -3.6
2.4.16.01. Beta-insect excitatory toxin BmKIT1 1wwn Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.2 ± 1.1 72 ± 6 -4.4
2.2.06.02. Cellular retinoic acid-binding protein 2 1cbs Homo sapiens Nuclear outer 1 0 7.1 ± 1.9 41 ± 13 -5.9
2.4.06.01. StAR-related lipid transfer protein 5 2r55 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 47 ± 19 -4.8
1.2.32.01. Cytochrome P450 2D6, conformation 4 4xry Homo sapiens Endoplasm. reticulum 1 0 8.8 ± 3.0 41 ± 2 -15.5
2.1.26.01. Colicin A channel-forming domain 1col Escherichia coli Secreted 1 0 1.8 ± 1.0 43 ± 11 -3.2
3.1.15.05. LsbB 2mlu Lactococcus lactis Secreted 1 0 4.4 ± 4.1 89 ± 2 -6.0
1.1.71.01. SidF, inhibitor of growth family, member 3 4fyg Legionella pneumophila Vacuole 1 0 8.1 ± 3.3 81 ± 10 -3.9
1.2.27.01. Fst toxin 2kv5 Enterococcus faecalis Bact. Gram-pos plas. 1 1 26.0 ± 2.9 35 ± 8 -18.9
2.1.01.01. Snake phospholipase A2, group I, isoform 3 3jql Naja sagittifera Secreted 1 0 6.2 ± 1.0 85 ± 5 -7.0
2.4.20.01. Cysteine protease 3ois Xylella fastidiosa Undefined 1 0 3.2 ± 0.2 80 ± 4 -6.4
1.1.01.02. Rhodopsin, inactive, structure 2 (with beta-ionone) 3oax Bos taurus Eukaryo. plasma 1 7 30.9 ± 1.4 11 ± 0 -73.6
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3g1q Trypanosoma brucei Endoplasm. reticulum 1 0 8.1 ± 1.5 62 ± 12 -10.8
2.2.34.01. Omega conotoxin SO3 1fyg Conus striatus Secreted 1 0 2.9 ± 1.1 76 ± 18 -3.5
2.2.34.02. U2-agatoxin-Aop1a 2e2s Allagelena opulenta Secreted 1 0 3.5 ± 0.7 45 ± 14 -5.7
1.1.25.02. Lactose permease lacY, structure at acidic pH 2cfp Escherichia coli Bact. Gram-neg inner 1 12 31.1 ± 1.4 2 ± 2 -85.4
1.1.01.02. Endothelin B receptor, with endothelin 5glh Homo sapiens Eukaryo. plasma 1 7 34.8 ± 1.0 6 ± 1 -81.5
2.2.34.02. Hybrid atracotoxin 2h1z Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 0.6 ± 2.0 82 ± 20 -1.9
1.1.01.02. Muscarinic acetylcholine receptor M2, active 4mqs Homo sapiens Eukaryo. plasma 1 7 32.2 ± 2.1 8 ± 3 -70.0
1.1.07.01. Nitric oxide reductase 3ayf Bacillus stearothermophilus Bact. Gram-pos plas. 1 14 31.6 ± 0.8 8 ± 0 -109.3
2.2.34.11. Leaf cyclotide 2 2kuk Viola hederacea Secreted 1 0 3.4 ± 1.2 83 ± 20 -5.9
1.1.75.02. Sec-independent protein translocase TatA 2lzr Escherichia coli Bact. Gram-neg inner 1 1 29.2 ± 1.8 26 ± 2 -29.1
2.4.05.01. Sterol carrier protein 2 1pz4 Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.8 ± 5.0 37 ± 49 -1.3
2.2.54.01. Non-structural protein 5A 3fqm Hepatitis C virus Endoplasm. reticulum 1 0 4.9 ± 1.1 77 ± 7 -7.5
2.2.30.01. Nawaprin 1udk Naja nigricollis Secreted 1 0 6.3 ± 1.0 81 ± 8 -7.3
2.4.16.13 Copsin 2mn5 Coprinopsis cinerea Secreted 1 0 3.0 ± 1.5 59 ± 9 -5.9
2.1.08.01. Cytochrome c551 451c Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 1.4 ± 0.9 85 ± 10 -5.4
2.2.11.01. Protein kinase C beta, C2 domain 1a25 Rattus norvegicus Eukaryo. plasma 1 0 3.1 ± 1.0 44 ± 18 -2.8
1.1.01.02. C-C chemokine receptor type 2 5t1a Homo sapiens Eukaryo. plasma 1 7 32.6 ± 1.4 3 ± 2 -80.2
2.4.50.01. Matrix protein, Indiana virus, complex with mRNA export factor 4owr Vesicular stomatitis virus Viral 1 0 2.1 ± 0.8 65 ± 2 -7.6
1.3.11.01. Serine protease EspP, post-cleavage structure 2qom Escherichia coli Bact. Gram-neg outer 1 12 25.1 ± 1.6 6 ± 7 -55.9
2.2.27.01. Rac GTPase-activating protein 1 4b6d Homo sapiens Eukaryo. plasma 1 0 3.5 ± 0.9 55 ± 4 -5.9
1.1.39.04. Nickel/cobalt transporter CbiM 4m58 Thermoanaerobacter tengcongensis Bact. Gram-pos plas. 1 7 29.8 ± 0.9 18 ± 2 -59.8
2.2.06.01. Extracellular fatty acid-binding protein 2kt4 Coturnix coturnix japonica (Japanese quail) Secreted 1 0 3.9 ± 2.9 61 ± 8 -3.4
3.1.05.03. VG16KRKP peptide, structure 1 2mxh Designed proteins Undefined 1 0 2.5 ± 2.4 82 ± 11 -3.2
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 3 3ksw Trypanosoma cruzi Endoplasm. reticulum 1 0 8.0 ± 6.7 61 ± 6 -9.1
2.3.06.06. Triacylglycerol lipase, open (active) state 1ein Humicola lanuginosa Secreted 1 0 8.1 ± 0.8 63 ± 4 -14.5
3.1.28.02. Neuromedin-C 2n0h Homo sapiens Secreted 1 0 4.1 ± 1.6 82 ± 18 -3.1
2.2.06.02. Adipocyte lipid-binding protein 1tow Homo sapiens Eukaryo. plasma 1 0 2.5 ± 1.7 51 ± 18 -4.5
1.1.01.06. Adiponectin receptor 1, open 5lxg Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.0 21 ± 0 -68.3
1.2.43.01. Envelope glycoprotein, chimeric 1k4r Dengue virus Viral 1 0 6.6 ± 2.4 21 ± 12 -4.9
2.3.01.09. Arabinogalactan endo-1,4-beta-galactosidase 1hjq Humicola insolens (Soft-rot fungus) Secreted 1 0 1.8 ± 1.4 86 ± 7 -3.7
1.3.21.01. Outer membrane usher protein FimD, complex with FimC-FimH 3rfz Escherichia coli Bact. Gram-neg outer 1 24 23.8 ± 0.8 5 ± 0 -65.1
1.1.01.05. Metabotropic glutamate receptor 5 4oo9 Homo sapiens Eukaryo. plasma 1 7 32.4 ± 1.2 2 ± 1 -66.3
2.4.16.01. Beta-toxin CsEI 1b3c Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.9 ± 1.2 70 ± 7 -3.9
1.1.25.06. D-xylose-proton symporter xylE, conformation 4 4qiq Escherichia coli Bact. Gram-neg inner 1 12 29.8 ± 1.8 1 ± 1 -72.6
2.4.15.01. Protein Nef, N-terminal helix (HIV HV1B1) 1zec Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.6 ± 4.1 89 ± 2 -6.8
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form 4ors Homo sapiens Endoplasm. reticulum 1 0 2.6 ± 0.8 71 ± 7 -3.7
3.1.11.04. Orexin-A 1wso Homo sapiens Secreted 1 0 6.4 ± 1.7 72 ± 14 -5.5
2.2.34.07. Asteropsin B 2lzx Asteropus sp. Secreted 1 0 2.2 ± 1.7 90 ± 21 -3.3
1.2.38.01. Penicillin-binding protein 1A 2oqo Aquifex aeolicus Bact. Gram-neg inner 1 0 3.0 ± 1.0 40 ± 6 -11.0
2.1.10.01. Glycolipid transfer protein, conformation 2 1swx Homo sapiens Eukaryo. plasma 1 0 4.6 ± 1.0 87 ± 8 -7.1
1.2.33.02. Monoamine oxidase A 1o5w Rattus norvegicus Mitochon. outer 1 1 31.4 ± 3.4 20 ± 3 -23.1
2.2.14.01. Lactadherin 3bn6 Bos taurus Secreted 1 0 2.8 ± 0.5 11 ± 4 -7.2
1.2.44.01. Amyloid beta A4 protein (peptide 672-699) 1amb Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 87 ± 0 -3.2
2.3.05.06. Endothelin-converting enzyme 2 2pxx Homo sapiens Golgi 1 0 7.1 ± 1.3 37 ± 8 -8.4
2.4.16.04. Defensin 3psm Pachyrhizus erosus Secreted 1 0 4.1 ± 1.8 32 ± 8 -5.4
1.1.08.01. F1F0 ATP synthase subunit c, deprotonated form 1c99 Escherichia coli Bact. Gram-neg inner 1 2 30.2 ± 3.0 36 ± 3 -30.7
2.3.06.11. Monoglyceride lipase 4zwn Saccharomyces cerevisiae Endoplasm. reticulum 1 0 4.3 ± 1.7 11 ± 17 -7.5
3.4.04.01. Daptomycin, Ca-free, different conformation 1t5m Streptomyces roseosporus Secreted 1 0 2.3 ± 1.3 33 ± 6 -7.9
3.1.21.04. Spiderine-1a 2n85 Oxyopes takobius (Lynx spider) Secreted 1 0 3.2 ± 4.2 88 ± 0 -7.8
2.1.38.01. Anion-specific porin B 2vql Corynebacterium glutamicum Bact. Gram-pos cell wall 1 0 6.2 ± 0.3 83 ± 2 -12.7
2.2.35.01. Streptolysin O 4hsc Streptococcus pyogenes Secreted 1 0 2.8 ± 3.5 15 ± 27 -5.1
2.4.43.01. Cell wall anchor protein of the T6SS system 4b62 Pseudomonas aeruginosa Bact. Gram-neg outer 1 0 2.8 ± 2.5 46 ± 36 -4.6
1.1.01.02. C-X-C chemokine receptor type 4, complex with peptide 4rws Homo sapiens Eukaryo. plasma 1 7 33.8 ± 1.5 9 ± 1 -76.9
3.2.01.04. Gomesin 1kfp Acanthoscurria gomesiana (Tarantula spider) Secreted 1 0 0.5 ± 1.0 75 ± 6 -2.7
1.2.44.01. Amyloid beta A4 protein (peptide 688-704), in water 2mj1 Homo sapiens Eukaryo. plasma 1 0 9.4 ± 3.4 38 ± 11 -7.4
2.2.05.01. Plantacyanin 1f56 Spinacia oleracea Thylakoid 1 0 1.4 ± 1.5 11 ± 15 -2.0
2.2.41.01. Alpha-defensin cryptdin-4 1tv0 Mus musculus Secreted 1 0 2.9 ± 1.4 67 ± 13 -4.5
3.1.28.08. Ocellatin-LB1 5u9v Leptodactylus labyrinthicus Secreted 1 0 4.7 ± 1.4 76 ± 4 -6.6
3.1.01.04. Ferredoxin, chloroplastic, transit peptide (1-32) 1fct Chlamydomonas reinhardtii Thylakoid 1 1 21.8 ± 6.7 28 ± 4 -8.4
2.1.29.01. Apolipoprotein A-I 2a01 Homo sapiens Secreted 1 0 4.8 ± 1.2 63 ± 11 -6.5
2.2.12.01. Ganglioside GM2 activator 1tjj Homo sapiens Lysosome 1 0 4.2 ± 0.3 57 ± 4 -8.3
1.1.01.02. TM1-TM2 fragment of fungal STE2 receptor 2k9p Saccharomyces cerevisiae Eukaryo. plasma 1 2 29.8 ± 3.1 21 ± 4 -10.5
1.1.56.01. Steryl-sulfatase 1p49 Homo sapiens Endoplasm. reticulum 1 2 29.6 ± 1.1 23 ± 0 -34.6
2.1.01.01. Myotoxin 1s8i Agkistrodon contortrix laticinctus Secreted 1 0 4.9 ± 0.7 83 ± 5 -10.6
2.1.62.01. Thuricin alpha 2l9x Bacillus cereus Secreted 1 0 7.1 ± 3.2 84 ± 7 -7.8
1.1.53.01. Integral Membrane Methyltransferase 4a2n Methanosarcina acetivorans Archaebac. 1 5 30.6 ± 1.2 10 ± 2 -58.3
1.3.17.02. BamACDE subcomplex, structure 1 5ekq Escherichia coli Bact. Gram-neg outer 1 16 23.4 ± 0.7 18 ± 0 -61.9
1.1.25.06. Glucose transporter GLUT5, outward-open 4ybq Rattus norvegicus Eukaryo. plasma 1 12 32.4 ± 3.0 5 ± 0 -110.6
3.1.07.01. Fusion peptide (983-887) of spike glycoprotein 2ruo Human SARS coronavirus Endosome 1 0 9.9 ± 4.0 72 ± 6 -9.0
3.1.15.04. Bacteriocin plantaricin J (PlnJ) 2khg Lactobacillus plantarum Secreted 1 0 5.4 ± 4.0 72 ± 2 -9.0
1.1.56.01. Lipooligosaccharide phosphoethanolamine transferase A (EptA) 5fgn Neisseria meningitidis Bact. Gram-neg inner 1 5 27.8 ± 1.4 35 ± 0 -53.8
2.3.06.07. Triacylglycerol lipase 2w22 Geobacillus thermocatenulatus Secreted 1 0 5.6 ± 0.0 86 ± 0 -22.4
1.3.01.01. Transmembrane beta-barrel platform protein 2jmm Designed proteins Undefined 1 8 23.9 ± 1.3 4 ± 4 -32.3
2.3.06.01. Acetylcholinesterase 1qon Drosophila melanogaster Eukaryo. plasma 1 0 5.5 ± 1.6 4 ± 13 -5.0
1.2.32.01. Cytochrome P450 2D6, conformation 1 2f9q Homo sapiens Endoplasm. reticulum 1 0 7.0 ± 1.8 29 ± 10 -12.0
1.2.50.01. Sticholysin II 1gwy Stoichactis helianthus Secreted 1 0 3.4 ± 1.9 35 ± 15 -5.0
3.2.05.02. Astexin-1, structure 2 2m37 Asticcacaulis excentricus Secreted 1 0 3.2 ± 1.1 83 ± 13 -5.1
1.1.01.01. Bacteriorhodopsin-I 4pxk Haloarcula marismortui Archaebac. 1 7 31.8 ± 1.4 11 ± 1 -72.7
2.1.02.01. Arachidonate 15-lipoxygenase 3rde Sus scrofa Eukaryo. plasma 1 0 6.9 ± 0.4 83 ± 1 -8.7
2.2.34.09. Psi-conotoxin PIIIF 1jlp Conus purpurascens (Purple cone) Secreted 1 0 2.1 ± 1.1 72 ± 30 -3.1
1.3.01.02. Outer membrane protein X (OMPX) 1qj8 Escherichia coli Bact. Gram-neg outer 1 8 23.6 ± 2.8 12 ± 5 -30.7
1.1.01.03. Glucagon receptor, structure 1 4l6r Homo sapiens Eukaryo. plasma 1 7 28.8 ± 1.8 20 ± 0 -46.7
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2 2w8d Bacillus subtilis Bact. Gram-pos plas. 1 0 0.0 ± 6.0 83 ± 58 -1.6
2.1.01.01. Myotoxin II 2aoz Atropoides nummifer Secreted 1 0 3.4 ± 0.7 80 ± 3 -11.8
2.3.10.01. Glycosyltransferase GtfA 1pn3 Amycolatopsis orientalis (Nocardia orientalis) Undefined 1 0 7.2 ± 1.0 80 ± 5 -7.7
2.3.14.01. Retinaldehyde-binding protein 1, closed state 3hx3 Homo sapiens Eukaryo. plasma 1 0 1.2 ± 2.9 77 ± 32 -4.8
2.4.06.01. Acyl-coenzyme A thioesterase 11 3fo5 Homo sapiens Endoplasm. reticulum 1 0 2.3 ± 1.4 57 ± 7 -3.9
2.2.34.02. Hanatoxin 1 1d1h Grammostola rosea (Chilean rose tarantula) Secreted 1 0 3.4 ± 1.7 68 ± 15 -4.2
2.3.06.07. Lipase L1, isoform 2 4fmp Bacillus stearothermophilus Secreted 1 0 5.0 ± 1.6 25 ± 12 -8.9
2.1.18.01. Annexin V 1hvf Homo sapiens Eukaryo. plasma 1 0 2.3 ± 1.5 79 ± 10 -5.4
3.1.20.01. Alpha-conotoxin-like EpI 1a0m Conus episcopatus (Bishop's cone) Secreted 1 0 3.3 ± 1.2 58 ± 9 -3.2
1.3.04.03. Lipid A acylase PagP 3gp6 Escherichia coli Bact. Gram-neg outer 1 8 24.7 ± 1.5 40 ± 1 -32.5
1.1.100.01. Voltage-sensor domain of phosphatase, conformation 1 4g80 Ciona intestinalis Eukaryo. plasma 1 4 29.4 ± 1.4 14 ± 1 -44.6
3.2.01.06. Retrocyclin-2 (HTD-2) 2atg Macaca mulatta Secreted 1 0 2.4 ± 0.6 87 ± 9 -5.6
3.2.01.09. Peptidomimetic TWLKKRRWKKAK-D-Pro-P 2m7j Designed proteins Undefined 1 0 1.0 ± 1.7 75 ± 37 -2.7
2.2.20.01. Cytohesin-2 1u27 Mus musculus Eukaryo. plasma 1 0 0.5 ± 2.4 53 ± 9 -2.4
3.1.07.08. Peptide of outer capsid glycoprotein VP7 (266-326) 2lm7 Rotavirus A Endoplasm. reticulum 1 0 10.2 ± 1.5 76 ± 0 -13.6
2.2.41.01. Beta-defensin 8 1e4r Mus musculus Secreted 1 0 2.8 ± 1.1 74 ± 19 -5.5
3.4.10.01. Methanobactin 2xjh Methylosinus trichosporium Secreted 1 0 0.7 ± 0.7 67 ± 7 -2.9
1.1.26.06. Uracil transporter UraA 3qe7 Escherichia coli Bact. Gram-neg inner 1 14 27.7 ± 1.2 16 ± 0 -79.3
2.2.06.02. Fatty acid-binding protein 2flj Locusta migratoria (Migratory locust) Eukaryo. plasma 1 0 1.2 ± 1.5 62 ± 10 -3.6
1.1.01.02. Adenosine receptor A2a, with triazole-carboximidamide antagonist 5uig Homo sapiens Eukaryo. plasma 1 7 30.6 ± 1.4 13 ± 4 -62.6
3.1.07.05. Nonstructural protein 4b, segment 1716-1755 2lvg Hepatitis C virus Viral 1 0 6.4 ± 0.7 82 ± 8 -11.4
2.1.20.01. Osteocalcin 1q8h Sus scrofa Secreted 1 0 2.3 ± 1.7 81 ± 17 -4.4
1.3.09.01. Lipid A deacylase LpxR 3fid Salmonella enterica Bact. Gram-neg outer 1 12 25.6 ± 2.0 24 ± 0 -58.6
1.1.26.01. MhsT transporter, inward-facing state 4us3 Bacillus halodurans Bact. Gram-pos plas. 1 11 29.8 ± 0.8 11 ± 1 -87.1
3.1.05.03. VG16KRKP peptide, structure 2 2n63 Designed proteins Undefined 1 0 2.5 ± 0.3 57 ± 4 -4.0
2.1.02.01. Linoleate 9/13-lipoxygenase, with N-terminal helix 4g33 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 4.3 ± 0.0 16 ± 0 -9.1
1.2.24.01. Protein Vpu, cytoplasmic domain, in DPC micelles 2k7y Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 4.5 ± 1.4 54 ± 17 -5.4
2.2.20.01. PH domain of oxysterol-binding protein homolog 3, fused with lysozyme 4iap Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.5 ± 2.3 81 ± 3 -3.6
2.3.06.07. Lipase L1, isoform 1 1ji3 Bacillus stearothermophilus Secreted 1 0 3.5 ± 1.7 22 ± 10 -8.0
2.1.25.05. Lacticin Q 2n8p Lactococcus lactis Secreted 1 0 3.5 ± 0.8 80 ± 6 -4.0
1.1.01.02. Beta-2 adrenergic receptor, active state, complex with G-protein 3sn6 Homo sapiens Eukaryo. plasma 1 7 31.0 ± 1.6 8 ± 1 -68.2
1.3.20.01. Enantio-pyochelin receptor FetA 3qlb Pseudomonas fluorescens Bact. Gram-neg outer 1 22 23.4 ± 0.8 7 ± 0 -75.3
2.2.20.01. Rho guanine nucleotide exchange factor 9, conformation 2 4mt6 Rattus norvegicus Eukaryo. plasma 1 0 3.0 ± 1.9 68 ± 4 -5.1
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 1 1zhx Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.9 90 ± 7 -5.0
2.4.16.01. Toxin BmKaIT1 1omy Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.0 ± 1.3 83 ± 10 -3.8
1.1.91.01. Delta(14)-sterol reductase 4quv Methylomicrobium alcaliphilum Bact. Gram-neg inner 1 10 28.2 ± 1.4 11 ± 3 -81.4
1.2.44.01. Amyloid beta A4 protein (peptide 672-711) 1ba4 Homo sapiens Eukaryo. plasma 1 0 6.0 ± 0.3 85 ± 5 -10.9
3.1.20.01. alpha-conotoxin MII 1mii Conus magus Secreted 1 0 2.7 ± 1.8 45 ± 19 -4.2
3.1.18.02. Phenol-soluble modulin alpha 3 peptide 5kgy Staphylococcus aureus Secreted 1 0 9.4 ± 1.0 73 ± 7 -17.3
2.1.31.01. Colicin-M 3da4 Escherichia coli Bact. Gram-neg inner 1 0 2.5 ± 0.9 49 ± 11 -5.5
1.3.25.01. Necrotic enteritis toxin B 4i0n Clostridium perfringens Secreted 1 0 1.6 ± 2.4 38 ± 7 -4.3
1.3.14.01. Fatty Acid Transporter FadL, delS3, open channel 2r88 Escherichia coli Bact. Gram-neg outer 1 14 24.0 ± 1.4 6 ± 2 -53.8
3.1.02.15. Glutamate receptor ionotropic, NMDA 1, TMH 2 2nr1 Homo sapiens Eukaryo. plasma 1 0 7.0 ± 3.7 84 ± 0 -12.5
2.3.06.12. Gibberellin receptor GID1 3ebl Oryza sativa (Rice) Nuclear inner 1 0 5.2 ± 1.5 59 ± 14 -9.1
3.1.24.01. Penaeidin-3a 1ueo Litopenaeus vannamei (Whiteleg shrimp) Secreted 1 0 1.3 ± 3.5 89 ± 2 -5.5
1.2.03.02. Cytotoxic T-lymphocyte protein 4 1dqt Mus musculus Eukaryo. plasma 1 0 3.4 ± 1.6 64 ± 4 -5.3
1.1.80.01. UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase 5lev Homo sapiens Endoplasm. reticulum 1 10 31.8 ± 1.0 5 ± 0 -93.5
2.3.06.01. Bile-salt activated lipase, conformation 2 1akn Bos taurus Secreted 1 0 3.8 ± 1.5 77 ± 15 -6.7
2.2.17.01. 6.5 kDa glycine-rich antifreeze protein 2pne Hypogastrura harveyi Secreted 1 0 1.7 ± 0.2 89 ± 5 -7.7
2.2.11.01. Protein kinase C delta 1yrk Homo sapiens Eukaryo. plasma 1 0 2.0 ± 1.6 52 ± 19 -1.8
2.4.16.02. Drosomycin 1myn Drosophila melanogaster Secreted 1 0 4.6 ± 1.2 10 ± 17 -6.0
2.1.20.01. Coagulation factor IX, GLA domain 1nl0 Homo sapiens Secreted 1 0 4.1 ± 0.9 38 ± 13 -4.4
1.2.04.01. Integrin alpha-X, cytoplasmic helix (peptide 1129-1163) 2luv Homo sapiens Eukaryo. plasma 1 0 4.0 ± 0.5 80 ± 7 -5.8
2.4.07.01. Nischarin 3p0c Homo sapiens Endosome 1 0 4.1 ± 0.5 82 ± 13 -7.0
2.4.16.08. Hydramacin-1 2k35 Hydra vulgaris Secreted 1 0 2.0 ± 0.2 87 ± 2 -4.3
1.3.02.01. Opacity protein opA60, structure 1 2maf Neisseria gonorrhoeae Bact. Gram-neg outer 1 8 23.8 ± 1.0 20 ± 1 -34.2
2.2.29.01. Multivesicular body subunit 12B 3tow Homo sapiens Endosome 1 0 4.5 ± 2.3 33 ± 22 -5.8
3.1.21.01. Papiliocin 2la2 Papilio xuthus Secreted 1 0 7.8 ± 2.0 62 ± 4 -7.4
1.1.01.02. Sphingosine 1-phosphate receptor 1 3v2y Homo sapiens Eukaryo. plasma 1 7 32.2 ± 1.4 10 ± 0 -65.9
2.3.06.06. Lipase 2ory Photbacterium lipolyticum Secreted 1 0 6.3 ± 1.1 62 ± 10 -12.0
2.3.01.10. Galactocerebrosidase 3zr5 Mus musculus Lysosome 1 0 5.2 ± 0.6 87 ± 1 -15.3
2.4.20.02. Arylamine N-acetyltransferase 1w4t Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 2.8 ± 0.4 82 ± 1 -5.8
2.2.11.01. E3 ubiquitin-protein ligase Itchy homolog 2nq3 Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.9 25 ± 17 -6.7
1.2.32.01. Cytochrome P450 2C8 1pq2 Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 1.8 65 ± 9 -8.6
2.1.01.01. Snake phospholipase A2-3, group II 1gmz Bothrops pirajai Secreted 1 0 3.8 ± 1.5 88 ± 10 -6.7
3.2.02.02. Conopeptide CnVA 3zkt Conus consors (Singed cone) Secreted 1 0 7.9 ± 2.9 88 ± 27 -5.2
1.1.64.01. Sodium/calcium exchanger, structure 2 3v5s Methanococcus jannaschii Archaebac. 1 10 29.6 ± 1.6 1 ± 2 -75.1
1.3.17.02. BamABCDE complex, structure 1 5ayw Escherichia coli Bact. Gram-neg outer 1 16 22.8 ± 1.2 7 ± 0 -57.5
2.4.07.01. PX domain of vacuolar morphogenesis protein VAM7 1kmd Saccharomyces cerevisiae Vacuole 1 0 3.4 ± 1.2 76 ± 8 -7.8
3.1.14.01. Neuropeptide K 2b19 Homo sapiens Secreted 1 0 5.1 ± 4.3 46 ± 8 -5.7
2.1.25.02. Carnocyclin A 2kjf Carnobacterium maltaromaticum Secreted 1 0 2.1 ± 1.1 61 ± 12 -4.6
3.1.05.08. MSI-594 derived peptide MSI-594-F5A 2l36 Designed proteins Undefined 1 0 6.9 ± 7.0 79 ± 3 -8.3
2.3.10.01. Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 3s2u Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 6.8 ± 0.9 60 ± 2 -8.3
2.2.11.01. Synaptotagmin-13 1wfm Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.9 88 ± 15 -4.5
1.2.32.01. Cytochrome P450 1A2 2hi4 Homo sapiens Endoplasm. reticulum 1 0 6.9 ± 1.0 66 ± 9 -16.2
2.3.06.08. Phospholipase A1 4qnn Vespa basalis Secreted 1 0 3.5 ± 0.5 64 ± 2 -11.1
3.2.05.02. Xanthomonin II 2mfv Xanthomonas gardneri Secreted 1 0 4.1 ± 0.9 38 ± 6 -4.4
2.2.11.01. Synaptotagmin-like protein 4 3fdw Homo sapiens Vesicle 1 0 3.0 ± 2.0 71 ± 17 -3.6
2.2.34.02. U5-theraphotoxin-Hh1a 1qk7 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 6.3 ± 0.5 47 ± 2 -5.2
2.2.14.01. Coagulation factor VIII, light chain 3j2s Homo sapiens Eukaryo. plasma 1 0 4.8 ± 1.0 34 ± 15 -6.1
1.2.18.01. Putative sortase 2wts Streptococcus pneumoniae Bact. Gram-pos plas. 1 0 5.1 ± 1.0 20 ± 3 -4.6
2.2.34.11. Cycloviolacin-O2 2kcg Viola odorata Secreted 1 0 5.1 ± 2.9 58 ± 36 -6.8
2.3.06.01. Neuroligin-2 3bl8 Mus musculus Eukaryo. plasma 1 0 1.7 ± 1.6 32 ± 5 -4.1
3.1.09.01. ICP47 protein, active domain (1-34) 1qlo Human herpesvirus Endoplasm. reticulum 1 0 8.6 ± 0.8 58 ± 8 -10.2
2.4.16.01. LQH III alpha-like toxin 1fh3 Leiurus quinquestriatus hebraeus Secreted 1 0 3.6 ± 1.5 83 ± 16 -5.2
2.1.25.04. Acidocin B 2mwr Lactobacillus acidophilus Secreted 1 0 4.9 ± 1.6 76 ± 0 -8.6
2.1.10.01. Glycolipid transfer protein, structure 2 1wbe Bos taurus Eukaryo. plasma 1 0 1.1 ± 2.4 89 ± 8 -9.4
1.1.105.01. CD81 antigen 5tcx Homo sapiens Eukaryo. plasma 1 4 34.2 ± 2.4 1 ± 1 -55.9
3.1.07.01. Fusion peptide (524-539) of ebolavirus glycoprotein GP2 2rlj Zaire ebolavirus Viral 1 0 5.8 ± 1.8 84 ± 6 -6.8
3.1.12.01. Sarafotoxin-B 1srb Atractaspis engaddensis (Israeli burrowing asp) Secreted 1 0 4.9 ± 1.9 62 ± 10 -4.1
1.3.15.01. Outer membrane protein G (OMPG), open state 1 2iwv Escherichia coli Bact. Gram-neg outer 1 14 25.3 ± 1.4 3 ± 5 -61.3
2.1.10.01. Accelerated-cell-death 11 apo-protein 4nt1 Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 2.0 85 ± 7 -5.4
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase 4fdo Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 4.3 ± 1.1 67 ± 4 -5.3
2.3.06.06. Lipase A, closed state 3guu Candida antarctica Secreted 1 0 4.4 ± 1.0 80 ± 2 -10.9
3.2.10.01. PawS derived peptide 4 2lws Designed proteins Undefined 1 0 7.5 ± 1.3 37 ± 13 -5.8
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 5 1kju Oryctolagus cuniculus Endoplasm. reticulum 1 10 33.8 ± 0.2 26 ± 1 -68.6
2.2.06.01. Neutrophil gelatinase-associated lipocalin 3fw5 Homo sapiens Secreted 1 0 2.0 ± 1.2 45 ± 9 -3.1
2.3.06.12. Sulfolobus shibatae 3wj1 Sulfolobus shibatae Secreted 1 0 3.1 ± 0.7 52 ± 6 -6.3
1.1.25.05. Di- or tripeptide transporter 4w6v Yersinia enterocolitica Bact. Gram-neg inner 1 14 29.8 ± 1.2 12 ± 1 -113.6
2.2.20.01. Triple functional domain protein 1nty Homo sapiens Eukaryo. plasma 1 0 3.2 ± 2.0 59 ± 16 -3.9
1.1.10.08. Multidrug resistance protein 1 (MRP1), structure 1 5uj9 Homo sapiens Eukaryo. plasma 1 17 31.0 ± 0.2 7 ± 0 -110.7
1.1.73.01. TrbI protein 2bhv Helicobacter pylori Bact. Gram-neg outer 1 0 3.1 ± 1.3 42 ± 11 -6.4
1.1.01.02. P2Y purinoceptor 12, structure 2 4pxz Homo sapiens Eukaryo. plasma 1 7 36.0 ± 1.9 4 ± 3 -79.5
1.1.39.03. Folate ECF transporter 4z7f Enterococcus faecalis Bact. Gram-pos plas. 1 6 30.6 ± 1.6 0 ± 1 -53.1
3.1.13.01. Calcitonin 1bku Anguilla japonica (Japanese eel) Secreted 1 0 3.0 ± 0.4 77 ± 3 -8.7
3.1.05.03. WYHRLSHLHSRLQD 5mxt Designed proteins Undefined 1 0 5.0 ± 0.8 77 ± 10 -6.3
2.1.41.01. Phosphatidylinositol 3-kinase catalytic subunit type 3 3ls8 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 75 ± 9 -4.7
3.1.21.08. Moricin 1x22 Spodoptera litura Secreted 1 0 4.4 ± 1.1 70 ± 5 -9.2
2.3.06.09. Cutinase 5ajh Fusarium oxysporum Secreted 1 0 6.2 ± 0.3 25 ± 9 -7.6
2.4.05.01. Sterol carrier protein 2 1c44 Oryctolagus cuniculus Eukaryo. plasma 1 0 3.7 ± 1.2 74 ± 17 -4.8
1.1.01.04. Smoothened homolog, monomer, structure 6 5v57 Homo sapiens Eukaryo. plasma 1 7 29.8 ± 1.0 20 ± 1 -60.7
1.2.43.01. Envelope glycoprotein, Zika virus, structure 6 5gzn Zika virus Viral 1 0 5.1 ± 2.6 41 ± 11 -4.9
2.4.52.01. Spondin-2 3d34 Homo sapiens Secreted 1 0 6.3 ± 0.7 35 ± 5 -10.4
1.3.19.01. Porin OpdQ 3t24 Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.0 ± 1.3 2 ± 0 -56.5
2.4.07.01. PX domain of sorting nexin-14 4bgj Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 72 ± 22 -4.3
2.3.16.06. ADP-ribosylation factor 1 (ARF1), different conformation 2ksq Saccharomyces cerevisiae Golgi 1 0 4.7 ± 0.1 62 ± 0 -10.4
2.4.16.05. Plectasin 3e7r Pseudoplectania nigrella (Ebony cup) Secreted 1 0 2.7 ± 2.3 53 ± 17 -4.0
1.1.25.05. Glutathione uptake transporter, structure 2 4uvm Shewanella oneidensis Bact. Gram-neg inner 1 14 29.8 ± 0.7 10 ± 0 -105.3
1.2.17.01. Vesicle-associated membrane protein 2 2kog Rattus norvegicus Eukaryo. plasma 1 1 34.8 ± 1.7 27 ± 1 -33.7
3.2.05.01. Siamycin II (tricyclic peptide RP71935) 1rpb Streptomyces sp. Secreted 1 0 4.2 ± 1.3 85 ± 15 -8.3
2.4.51.01. Heme acquisition protein HasA, dimer 4y4s Yersinia pseudotuberculosis Secreted 1 0 1.8 ± 1.1 83 ± 9 -4.2
2.4.03.01. Tubby protein, ligand-bound 1i7e Mus musculus Eukaryo. plasma 1 0 3.8 ± 1.9 75 ± 13 -4.7
1.2.32.01. Cytochrome P450 24a1 (1,25-dihydroxyvitamin D(3) 24-hydroxylase) 3k9v Rattus norvegicus Mitochon. inner 1 0 6.6 ± 1.0 49 ± 6 -9.6
1.1.83.01. Mitochondrial translocator protein, TSPO, model 2 2n02 Mus musculus Mitochon. outer 1 7 28.4 ± 1.6 8 ± 3 -25.3
2.3.06.07. Lipase 3auk Geobacillus sp. Secreted 1 0 5.6 ± 0.8 25 ± 2 -8.5
1.3.06.02. Carbapenem-associated resistance porin CarO3 4fuv Acinetobacter baumannii Bact. Gram-neg outer 1 8 25.0 ± 2.3 3 ± 1 -38.5
1.2.03.05. Erythropoietin receptor (236-284) 2mv6 Homo sapiens Eukaryo. plasma 1 1 31.4 ± 3.3 34 ± 6 -36.3
1.2.41.01. Acyl-CoA-binding domain-containing protein 4 2wh5 Homo sapiens Peroxisome 1 0 7.2 ± 2.4 77 ± 26 -5.7
3.1.21.06. Stomoxyn 1zrx Stomoxys calcitrans (Stable fly) Secreted 1 0 5.7 ± 0.0 80 ± 0 -12.3
1.1.25.09. Iron-regulated transporter, inward-facing state 5ayo Bdellovibrio bacteriovorus Bact. Gram-neg inner 1 12 31.6 ± 0.7 7 ± 1 -89.2
2.1.49.01. cGMP-specific 3',5'-cyclic phosphodiesterase 1rkp Homo sapiens Eukaryo. plasma 1 0 5.0 ± 1.6 61 ± 11 -5.2
2.2.39.01. Cytotoxin-1 1rl5 Naja naja oxiana Secreted 1 0 5.2 ± 2.0 51 ± 16 -5.7
3.1.19.01. Bergofungin A 5mas Emericellopsis donezkii Secreted 1 1 30.8 ± 1.5 35 ± 20 -13.2
1.1.34.01. Mitochondrial ADP-ATP carrier, conformation 2 4c9q Saccharomyces cerevisiae Mitochon. inner 1 6 30.2 ± 1.1 4 ± 1 -57.7
1.1.38.01. H+-driven MATE exporter, outward-open, "bent" conformation 3vvo Pyrococcus furiosus Archaebac. 1 12 31.4 ± 1.1 11 ± 0 -93.1
1.1.33.01. Bile acid sodium symporter ASBT, inward-open conformation 3zuy Neisseria meningitidis Bact. Gram-neg inner 1 10 29.8 ± 1.5 15 ± 2 -82.3
3.1.19.01. Zervamicin IIb, transmembrane orientation 1r9u Emericellopsis salmosynnemata Secreted 1 1 23.2 ± 5.4 38 ± 7 -15.0
2.4.51.01. Heme acquisition protein HasA 1b2v Serratia marcescens Secreted 1 0 1.9 ± 1.6 18 ± 18 -3.3
1.3.15.02. CymA protein, conformation 2 4d5b Klebsiella oxytoca Bact. Gram-neg outer 1 14 23.4 ± 1.0 3 ± 1 -48.7
1.1.01.02. Neurotensin receptor type 1, structure 3 4xes Rattus norvegicus Eukaryo. plasma 1 7 31.8 ± 1.4 5 ± 1 -68.3
2.4.16.10. Toxin MIT1 (Black mamba intestinal toxin 1) 1imt Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 4.8 ± 0.7 70 ± 3 -9.1
1.1.69.01. HIG1 domain family member 1A 2lom Homo sapiens Eukaryo. plasma 1 2 22.0 ± 5.0 1 ± 1 -27.3
2.2.34.02. Psalmotoxin-1 1lmm Psalmopoeus cambridgei (Trinidad chevron tarantula) Secreted 1 0 2.4 ± 1.6 71 ± 15 -4.4
2.3.14.01. Yeast Sec14 Homolog Sfh1 (YKL091C) 3b7n Saccharomyces cerevisiae Nuclear outer 1 0 2.9 ± 1.5 65 ± 18 -5.8
1.1.25.02. Lactose permease LacY, structure 6 5gxb Escherichia coli Bact. Gram-neg inner 1 12 33.8 ± 1.5 1 ± 1 -89.6
1.2.39.01. Endoplasmic reticulum aminopeptidase 1, different conformation 2yd0 Homo sapiens Endoplasm. reticulum 1 0 4.1 ± 2.2 59 ± 8 -4.6
2.1.27.01. Cry3Bb1 1ji6 Bacillus thuringiensis Secreted 1 0 3.8 ± 1.6 64 ± 6 -4.2
3.1.28.05. Peptoid analogue of maculatin 2mmj Litoria genimaculata Secreted 1 0 10.0 ± 4.6 73 ± 3 -13.1
1.3.20.01. Ferredoxin receptor FusA 4zgv Pectobacterium atrosepticum Bact. Gram-neg outer 1 22 23.6 ± 0.7 7 ± 0 -65.8
2.1.29.03. Cholesteryl ester transfer inhibitor protein 1eze Papio hamadryas (Hamadryas baboon) Secreted 1 0 4.6 ± 0.2 89 ± 3 -9.9
2.1.01.01. Snake phospholipase A2 homolog 1, group II 2ok9 Bothrops pirajai Secreted 1 0 3.5 ± 1.4 76 ± 7 -7.6
1.1.01.02. Beta-2 adrenergic receptor, active state, complex with antibody 3p0g Homo sapiens Eukaryo. plasma 1 7 30.1 ± 1.4 9 ± 1 -62.9
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 1 2wuz Trypanosoma cruzi Endoplasm. reticulum 1 0 4.0 ± 1.1 75 ± 11 -9.9
2.2.34.01. Delta conotoxin EVIA 1g1z Conus ermineus Secreted 1 0 6.5 ± 1.9 72 ± 18 -8.7
3.2.01.01. Arenicin-1 2jsb Arenicola marina Secreted 1 0 2.4 ± 2.1 80 ± 11 -5.2
1.1.25.01. Glycerol-3-phosphate transporter glpT 1pw4 Escherichia coli Bact. Gram-neg inner 1 12 31.2 ± 1.4 1 ± 7 -92.5
1.1.01.02. Endothelin B receptor 5gli Homo sapiens Eukaryo. plasma 1 7 33.6 ± 1.4 11 ± 0 -77.6
2.2.11.01. C2A domain of synaptotagmin-5 5h4y Homo sapiens Vesicle 1 0 2.3 ± 2.3 29 ± 11 -4.5
2.2.34.02. Kappa-hexatoxin-Hv1c 1dl0 Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 1.7 ± 1.3 53 ± 17 -3.1
1.1.15.01. Neuronal acetylcholine receptor, alpha-7 2maw Homo sapiens Eukaryo. plasma 1 4 30.0 ± 1.4 14 ± 1 -41.4
1.2.38.01. Monofunctional glycosyltransferase 3vmr Staphylococcus aureus Bact. Gram-pos plas. 1 1 30.8 ± 1.2 25 ± 2 -35.4
2.2.34.11. Leaf cyclotide 1 1za8 Viola hederacea Secreted 1 0 4.9 ± 1.3 48 ± 24 -8.5
2.2.09.01. Kelch-like protein 7 3ii7 Homo sapiens Undefined 1 0 2.6 ± 1.8 90 ± 16 -6.5
2.2.20.01. PH domain of pleckstrin homology domain-containing family A member 3 2mdx Homo sapiens Eukaryo. plasma 1 0 5.1 ± 1.1 11 ± 19 -4.1
1.2.32.01. Steroid 21-hydroxylase (P450 C21) 3qz1 Bos taurus Endoplasm. reticulum 1 0 5.9 ± 1.6 72 ± 3 -10.4
2.2.39.01. Cytotoxin 1 ( Cardiotoxin gamma) 1tgx Naja mossambica pallida Secreted 1 0 6.7 ± 1.0 59 ± 12 -10.0
2.1.44.01. Bacteriocin ASM1 2mvi Lactobacillus plantarum Secreted 1 0 5.3 ± 1.4 33 ± 5 -4.9
2.1.08.02. Cytochrome c4 1m70 Pseudomonas stutzeri Bact. Gram-neg inner 1 0 5.4 ± 0.8 67 ± 14 -5.6
2.2.11.01. Rab3 interacting molecule 2 (RIM2), C2A domain 2bwq Rattus norvegicus Eukaryo. plasma 1 0 1.5 ± 1.6 41 ± 19 -1.8
3.1.11.02. Glucagon-like peptide 2 2l64 Homo sapiens Secreted 1 0 3.9 ± 0.3 90 ± 5 -10.8
1.3.20.01. Outer membrane cobalamin transporter BtuB, meso form 2guf Escherichia coli Bact. Gram-neg outer 1 22 23.4 ± 0.9 6 ± 7 -69.3
2.2.27.01. C1 domain of protein kinase C gamma 2e73 Homo sapiens Eukaryo. plasma 1 0 3.5 ± 1.3 53 ± 9 -4.7
1.1.30.01. Membrane protein insertase YidC 2 3wo7 Bacillus halodurans Bact. Gram-pos plas. 1 5 29.0 ± 1.3 12 ± 0 -58.2
3.1.13.01. Islet amyloid polypeptide, fragment 34-70, alternative structure 2l86 Homo sapiens Secreted 1 0 6.2 ± 0.8 88 ± 7 -9.6
3.4.07.01. VG16KRKP peptide 2mwl Designed proteins Undefined 1 0 4.4 ± 1.3 79 ± 12 -3.6
1.2.04.01. Integrin alpha-IIb, cytoplasmic domain 1s4w Homo sapiens Eukaryo. plasma 1 0 2.9 ± 0.3 69 ± 3 -9.1
1.2.32.01. Cytochrome P450 2B4, closed state 2 2q6n Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.5 ± 0.4 55 ± 2 -13.0
2.3.06.06. Triacylglycerol lipase 1lgy Rhizopus niveus Secreted 1 0 1.9 ± 1.8 33 ± 16 -4.8
3.2.05.02. Chaxapeptin 1 2n5c Streptomyces leeuwenhoekii Secreted 1 0 7.2 ± 1.0 82 ± 9 -8.8
1.1.60.01. Protease GlpG 2nr9 Haemophilus influenzae Bact. Gram-neg inner 1 6 28.2 ± 1.6 13 ± 3 -52.0
2.2.06.02. Fatty acid-binding protein homolog 1 1o8v Echinococcus granulosus Eukaryo. plasma 1 0 2.9 ± 1.0 48 ± 15 -5.8
1.1.01.06. Adiponectin receptor 2 5lwy Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.4 16 ± 0 -78.0
1.2.43.01. Envelope glycoprotein, Dengue virus type 3 1uzg Dengue virus Viral 1 0 5.7 ± 2.7 18 ± 7 -5.4
2.2.12.03. Immunogenic protein MPT63 1lmi Mycobacterium tuberculosis Secreted 1 0 2.2 ± 1.9 86 ± 7 -4.3
3.1.02.14. Tumor-associated calcium signal transducer 2, peptide 304-322 2mae Homo sapiens Eukaryo. plasma 1 0 3.7 ± 3.0 82 ± 0 -3.7
2.4.16.01. Toxin CsEv1 1vna Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.9 ± 1.0 65 ± 10 -7.8
1.1.25.05. Dipeptide permease D 4q65 Escherichia coli Bact. Gram-neg inner 1 14 30.2 ± 0.8 7 ± 1 -101.4
2.4.15.01. Protein Nef 1avv Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.0 ± 1.5 75 ± 13 -3.4
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form, mutant 4os0 Homo sapiens Endoplasm. reticulum 1 0 2.4 ± 1.0 77 ± 4 -3.1
3.1.21.05. Poneratoxin 1g92 Paraponera clavata Secreted 1 0 22.8 ± 8.5 29 ± 7 -12.9
2.2.34.07. Asteropsin D 2lzy Asteropus sp. Secreted 1 0 4.7 ± 1.5 49 ± 29 -3.0
1.2.38.01. Penicillin-binding protein 1B 5hlb Escherichia coli Bact. Gram-neg inner 1 1 30.0 ± 2.0 33 ± 1 -21.7
2.1.10.01. Glycolipid transfer protein, conformation 1 1sx6 Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.1 85 ± 5 -10.1
1.1.34.01. Mitochondrial ADP-ATP carrier 1okc Bos taurus Mitochon. inner 1 6 29.5 ± 1.7 14 ± 1 -44.6
1.2.40.01. Mitochondria fission 1 protein, crystal structure 1nzn Homo sapiens Mitochon. outer 1 0 6.1 ± 1.4 72 ± 8 -9.3
2.4.06.03. Class 10 plant pathogenesis-related protein 2qim Lupinus luteus Secreted 1 0 3.3 ± 1.4 41 ± 3 -3.1
1.2.44.01. Amyloid beta A4 protein (peptide 696-706) 1qcm Homo sapiens Eukaryo. plasma 1 0 2.6 ± 1.5 78 ± 17 -2.9
2.4.16.04. Defensin 1ti5 Vigna radiata (Mung bean) Secreted 1 0 1.9 ± 2.4 62 ± 16 -3.0
1.1.08.01. F1F0 ATP synthase subunit c, double mutant 1l6t Escherichia coli Bact. Gram-neg inner 1 2 30.0 ± 4.4 36 ± 3 -28.2
1.2.39.02. Stromelysin-1 1c3i Homo sapiens Eukaryo. plasma 1 0 3.6 ± 1.7 85 ± 17 -4.4
1.2.32.01. Lanosterol 14-alpha demethylase 5jlc Candida glabrata Endoplasm. reticulum 1 1 29.8 ± 0.7 25 ± 1 -31.5
2.1.03.01. Alpha-toxin, different sequence (PHLC2_CLOPE in Uniprot) 1kho Clostridium perfringens Secreted 1 0 3.8 ± 1.0 87 ± 4 -8.2
2.2.35.01. Pneumolysin, structure 7 4zgh Streptococcus pneumoniae Secreted 1 0 5.0 ± 2.5 24 ± 25 -4.9
1.1.46.01. MerF bacterial mercury uptake transporter, structure 1 2lj2 Morganella morganii Bact. Gram-neg inner 1 2 28.8 ± 2.4 19 ± 1 -37.9
2.3.06.02. MPT51/MPB51 antigen 1r88 Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 1.8 ± 1.0 2