PDB ID or protein name

All proteins in OPM (3706 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.1.25.03. Enterocin 7A 2m5z Enterococcus faecalis Secreted 0 0 4.4 ± 0.3 57 ± 3 -5.3
2.1.63.01. Phosphatidylinositol mannoside acyltransferase PatA 5f34 Mycobacterium smegmatis Bact. Gram-pos plas. 0 0 3.9 ± 0.5 58 ± 1 -6.9
3.1.30.01. Lactoferricin peptide (36-59) 5id5 Sus scrofa Secreted 1 0 7.4 ± 1.0 87 ± 9 -6.2
3.1.19.01. Chrysospermin C 1ee7 Apiocrea chrysosperma Secreted 1 0 9.8 ± 2.3 82 ± 12 -12.2
1.1.51.01. Vitamin K epoxide reductase, conformation 1 4nv6 Synechococcus sp. Bact. Gram-neg inner 1 5 29.8 ± 1.8 1 ± 1 -54.2
2.2.20.01. Triple functional domain protein 1nty Homo sapiens Eukaryo. plasma 1 0 3.2 ± 2.0 59 ± 16 -3.9
1.1.10.08. Multidrug resistance protein 1 (MRP1), structure 2 5uja Bos taurus Eukaryo. plasma 1 17 31.4 ± 0.8 16 ± 0 -103.8
3.1.07.02. Juxtamembrane peptide (636-662) of protein gp160 2me3 Human immunodeficiency virus type 1 Endosome 1 0 6.1 ± 0.4 81 ± 7 -12.4
2.1.44.01. Bacteriocin glycocin F 2kuy Lactobacillus plantarum Secreted 1 0 5.4 ± 1.2 65 ± 6 -6.2
1.3.11.01. Serine protease EspP, pre-cleavage structure 3slj Escherichia coli Bact. Gram-neg outer 1 12 25.4 ± 1.2 6 ± 1 -53.1
1.1.01.02. P2Y purinoceptor 12, structure 2 4pxz Homo sapiens Eukaryo. plasma 1 7 36.0 ± 1.9 4 ± 3 -79.5
1.2.33.02. Alpha-glycerophosphate oxidase (GlpO) 2rgh Streptomyces sp. Bact. Gram-pos plas. 1 0 3.9 ± 1.4 71 ± 12 -6.2
2.2.39.01. Cytotoxin-1, minor form 5lue Naja naja oxiana Secreted 1 0 5.7 ± 0.8 87 ± 13 -7.6
2.1.41.01. Phosphatidylinositol 3-kinase catalytic subunit type 3 3ls8 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 75 ± 9 -4.7
1.2.25.01. Phospholamban, monomer 1n7l Oryctolagus cuniculus Endoplasm. reticulum 1 1 29.8 ± 3.6 34 ± 12 -32.3
2.1.01.01. Snake phospholipase A2, group II, VRV-PL-VIIIa 1zwp Daboia russelli pulchella Secreted 1 0 4.9 ± 1.0 76 ± 7 -12.5
3.2.04.03. Peptide leucine arginine 2m3n Lithobates pipiens Secreted 1 0 4.7 ± 0.6 83 ± 5 -5.7
1.2.12.01. Fimbrial protein, monomer 1oqw Pseudomonas aeruginosa Bact. Gram-neg inner 1 1 29.8 ± 3.0 31 ± 8 -28.9
2.4.05.01. Sterol carrier protein 2 1c44 Oryctolagus cuniculus Eukaryo. plasma 1 0 3.7 ± 1.2 74 ± 17 -4.8
1.1.01.03. Glucagon-like peptide 1 receptor with G-protein 5vai Oryctolagus cuniculus Eukaryo. plasma 1 7 30.6 ± 1.6 12 ± 4 -48.2
1.1.71.01. Legionalla phosphoinositide phosphatase, SidP 4jza Legionella pneumophila Vacuole 1 0 2.6 ± 1.7 57 ± 7 -5.6
3.1.15.03. Bacteriocin peptide plantaricin F (PlnF) 2rlw Lactobacillus plantarum Secreted 1 0 8.7 ± 4.4 79 ± 5 -11.7
1.1.26.05. Amino acid transporter ApcT, inward-facing conformation 3gia Methanococcus jannaschii Archaebac. 1 12 29.9 ± 1.4 11 ± 2 -92.1
2.2.50.01. Lipoprotein TP0453, open conformation 3k8i Treponema pallidum Bact. Gram-neg outer 1 0 8.9 ± 2.4 38 ± 2 -12.0
2.4.07.01. PX domain of sorting nexin-14 4bgj Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 72 ± 22 -4.3
2.1.47.01. Group 2 truncated hemoglobin glbO 2qrw Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 4.5 ± 1.0 52 ± 3 -5.5
2.3.01.01. Glucosylceramidase 1ogs Homo sapiens Lysosome 1 0 4.2 ± 1.1 89 ± 4 -9.0
1.2.17.01. Vesicle-associated membrane protein 2 2kog Rattus norvegicus Eukaryo. plasma 1 1 34.8 ± 1.7 27 ± 1 -33.7
1.2.32.01. Cytochrome P450 2B6, conformation 2 3ua5 Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 1.1 55 ± 3 -12.9
2.2.34.11. Kalata B2, segment 71-98 (repeat 1) 1pt4 Oldenlandia affinis Secreted 1 0 4.6 ± 1.2 83 ± 14 -9.2
2.1.60.03. Pseudecin, conformation 1 2ddb Pseudechis porphyriacus Secreted 1 0 4.8 ± 0.7 90 ± 3 -5.4
2.1.08.01. Cytochrome c peroxidase 1nml Marinobacter hydrocarbonoclasticus Bact. Gram-neg inner 1 0 2.2 ± 0.4 83 ± 0 -7.9
2.4.03.01. Tubby protein, ligand-bound 1i7e Mus musculus Eukaryo. plasma 1 0 3.8 ± 1.9 75 ± 13 -4.7
2.2.11.01. Synaptotagmin-7, C2A- and C2B-domains 6ank Rattus norvegicus Eukaryo. plasma 1 0 2.3 ± 0.6 66 ± 6 -5.2
2.2.34.02. Delta-amaurobitoxin-Pl1a 1v90 Pireneitega luctuosa (Tangled nest spider) Secreted 1 0 2.9 ± 0.7 26 ± 14 -4.0
2.2.23.01. Lipoprotein BamB, conformation 3 3q7o Escherichia coli Bact. Gram-neg outer 1 0 4.9 ± 1.5 69 ± 3 -6.9
1.2.03.05. Erythropoietin receptor (236-284) 2mv6 Homo sapiens Eukaryo. plasma 1 1 31.4 ± 3.3 34 ± 6 -36.3
1.1.25.05. Proton-dependent oligopeptide transporter, conformation 2 4iky Geobacillus kaustophilus Bact. Gram-pos plas. 1 14 31.8 ± 1.3 4 ± 0 -115.6
2.3.06.09. Cutinase 1 3gbs Aspergillus oryzae Secreted 1 0 11.2 ± 0.5 55 ± 5 -12.6
2.3.14.01. Yeast Sec14 Homolog Sfh1 (YKL091C) 3b7n Saccharomyces cerevisiae Nuclear outer 1 0 2.9 ± 1.5 65 ± 18 -5.8
2.1.49.01. cGMP-specific 3',5'-cyclic phosphodiesterase 1rkp Homo sapiens Eukaryo. plasma 1 0 5.0 ± 1.6 61 ± 11 -5.2
1.2.32.01. Cytochrome P450 2C19 4gqs Homo sapiens Endoplasm. reticulum 1 0 6.4 ± 2.1 71 ± 5 -9.5
2.4.16.02. Defensin ARD1 1ozz Archaeoprepona demophon Secreted 1 0 4.9 ± 1.7 31 ± 17 -7.1
3.1.21.01. Aedesin 2mmm Aedes aegypti (Yellowfever mosquito) Secreted 1 1 20.8 ± 0.8 11 ± 3 -12.3
2.1.21.04. Matrix protein p19 1a6s Rous sarcoma virus Viral 1 0 3.1 ± 2.7 89 ± 14 -3.6
3.1.11.01. Peptide YY 2dez Homo sapiens Secreted 1 0 4.0 ± 0.2 84 ± 2 -5.9
1.1.90.02. CDP-archaeol synthase 5guf Aeropyrum pernix Archaebac. 1 5 28.2 ± 1.4 15 ± 0 -48.6
1.3.20.01. Bacterial Zn-transporter ZnuD, structure 1 4rdr Neisseria meningitidis Bact. Gram-neg outer 1 22 23.2 ± 0.9 2 ± 0 -70.1
3.1.04.08. Truncated superoxide dismutase 1 2mp3 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 83 ± 0 -6.3
2.1.01.01. Phospholipase A2 2not Notechis scutatus scutatus (Mainland tiger snake) Secreted 1 0 2.6 ± 1.5 73 ± 8 -3.9
1.1.110.01. Apolipoprotein N-acyl transferase, structure 3 5vrg Escherichia coli Bact. Gram-neg inner 1 8 30.2 ± 1.2 2 ± 1 -70.7
1.1.01.02. Sphingosine 1-phosphate receptor 1 3v2y Homo sapiens Eukaryo. plasma 1 7 32.2 ± 1.4 10 ± 0 -65.9
2.3.06.01. Bile-salt activated lipase, structure 1 1f6w Homo sapiens Secreted 1 0 1.8 ± 0.5 81 ± 10 -5.1
2.3.06.01. Carboxylic ester hydrolase, open state 4be9 Ophiostoma piceae Secreted 1 0 8.7 ± 0.4 88 ± 2 -30.9
2.2.11.01. E3 ubiquitin-protein ligase Itchy homolog 2nq3 Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.9 25 ± 17 -6.7
2.3.05.01. Flavoprotein-ubiquinone oxydoreductase 2gmh Sus scrofa Mitochon. inner 1 0 7.2 ± 0.8 38 ± 4 -18.5
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 2 3c6e Dengue virus Viral 1 0 2.9 ± 2.7 42 ± 5 -3.6
1.1.35.01. Sodium/proton antiporter 1 (NhaA) 1zcd Escherichia coli Bact. Gram-neg inner 1 14 28.4 ± 1.4 2 ± 2 -78.6
2.1.63.01. Lipid A biosynthesis lauroyl acyltransferase 5kn7 Acinetobacter baumannii Bact. Gram-neg outer 1 0 7.4 ± 1.4 66 ± 0 -7.5
2.4.13.01. Oxysterol-binding protein homolog 4 (KES1), N-terminal helix removed 1zi7 Saccharomyces cerevisiae Golgi 1 0 2.5 ± 0.5 75 ± 8 -6.9
2.1.24.01. Saposin D (peptide 405-486) 2rb3 Homo sapiens Secreted 1 0 2.2 ± 1.7 88 ± 10 -3.4
2.2.09.01. Kelch-like protein 7 3ii7 Homo sapiens Undefined 1 0 2.6 ± 1.8 90 ± 16 -6.5
1.1.80.01. UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase 5lev Homo sapiens Endoplasm. reticulum 1 10 31.8 ± 1.0 5 ± 0 -93.5
3.1.14.01. Neurokinin A 1n6t Gallus gallus Secreted 1 0 6.8 ± 1.2 60 ± 17 -4.9
2.2.11.01. Synaptotagmin-13 1wfm Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.9 88 ± 15 -4.5
1.1.34.01. Mitochondrial ADP-ATP carrier, conformation 1 4c9g Saccharomyces cerevisiae Mitochon. inner 1 6 31.4 ± 1.5 1 ± 1 -54.6
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 1 3mok Pseudomonas aeruginosa Secreted 1 0 4.5 ± 0.7 37 ± 7 -6.7
1.1.63.01. Type 1 signal peptidase, complex with lipopeptide inhibitor 1t7d Escherichia coli Bact. Gram-neg inner 1 0 3.9 ± 1.0 65 ± 11 -7.6
1.1.117.01. Palmitoyltransferase 6bms Danio rerio Golgi 1 4 29.0 ± 2.6 10 ± 3 -42.1
3.4.07.01. VG16KRKP peptide 2mwl Designed proteins Undefined 1 0 4.4 ± 1.3 79 ± 12 -3.6
2.2.06.01. Outer membrane lipoprotein Blc 1qwd Escherichia coli Bact. Gram-neg outer 1 0 3.2 ± 2.0 80 ± 15 -4.6
2.2.14.01. Coagulation factor VIII, light chain 3j2s Homo sapiens Eukaryo. plasma 1 0 4.8 ± 1.0 34 ± 15 -6.1
2.3.06.06. Triacylglycerol lipase, closed state 2 5ap9 Humicola lanuginosa Secreted 1 0 5.7 ± 0.4 79 ± 5 -6.1
2.3.06.01. Neuroligin-2 3bl8 Mus musculus Eukaryo. plasma 1 0 1.7 ± 1.6 32 ± 5 -4.1
1.1.09.01. Calcium ATPase, E1P-ADP state 2zbd Oryctolagus cuniculus Endoplasm. reticulum 1 10 31.8 ± 1.4 22 ± 2 -70.6
2.2.34.11. Kalata-B8 2b38 Oldenlandia affinis Secreted 1 0 5.5 ± 1.0 88 ± 12 -5.6
2.1.10.01. Glycolipid transfer protein, structure 2 1wbe Bos taurus Eukaryo. plasma 1 0 1.1 ± 2.4 89 ± 8 -9.4
1.1.01.02. Cannabinoid receptor 1, structure 2 5u09 Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 9 ± 0 -71.8
3.1.07.05. Nonstructural protein, membrane-bound domain 1fw5 Semiliki forest virus Endosome 1 0 7.9 ± 1.5 73 ± 17 -10.2
2.2.34.06. Antimicrobial peptide 1 1dkc Phytolacca americana (American pokeweed) Secreted 1 0 3.5 ± 1.2 84 ± 10 -4.1
1.3.19.01. Protein OpdK 2qtk Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.3 ± 1.0 3 ± 0 -62.4
2.1.10.01. Accelerated-cell-death 11 apo-protein 4nt1 Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 2.0 85 ± 7 -5.4
2.4.11.01. Alpha-1-purothionin 2plh Triticum aestivum Secreted 1 0 2.4 ± 2.0 53 ± 17 -4.6
1.3.19.01. BenF-like porin 3jty Pseudomonas fluorescens Bact. Gram-neg outer 1 18 24.2 ± 1.2 1 ± 0 -59.8
2.2.27.01. C1 domain of protein kinase C gamma 2e73 Homo sapiens Eukaryo. plasma 1 0 3.5 ± 1.3 53 ± 9 -4.7
2.2.08.01. Osmotin-like protein 1aun Nicotiana tabacum Secreted 1 0 5.8 ± 1.0 85 ± 11 -6.7
3.1.28.07. Hylin-A1 analogs 5j6v Hypsiboas albopunctatus Secreted 1 0 21.2 ± 2.2 33 ± 16 -10.4
1.2.52.01. Cytochrome c-type biogenesis protein CcmE 1sr3 Escherichia coli Bact. Gram-neg inner 1 0 2.8 ± 2.7 59 ± 6 -2.2
1.2.04.01. Integrin alpha-IIb, cytoplasmic domain 1s4w Homo sapiens Eukaryo. plasma 1 0 2.9 ± 0.3 69 ± 3 -9.1
2.1.01.01. Snake phospholipase A2, group I 1poa Naja atra Secreted 1 0 4.8 ± 1.0 89 ± 7 -10.7
2.4.51.01. Heme acquisition protein HasA, apoprotein 4jes Yersinia pestis Secreted 1 0 5.2 ± 0.3 40 ± 2 -9.6
2.2.06.02. Fatty acid-binding protein homolog 1 1o8v Echinococcus granulosus Eukaryo. plasma 1 0 2.9 ± 1.0 48 ± 15 -5.8
3.1.07.02. Cytoplasmic tail (750-854) of protein gp41 5vwl Human immunodeficiency virus type 1 Endosome 1 1 20.8 ± 0.2 24 ± 0 -14.4
3.4.09.01. Granin 1lv4 Homo sapiens Secreted 1 0 1.8 ± 0.4 81 ± 3 -6.8
2.2.23.01. Lipoprotein BamB, conformation 2 3p1l Escherichia coli Bact. Gram-neg outer 1 0 3.6 ± 2.8 89 ± 10 -6.4
3.1.02.14. Tumor-associated calcium signal transducer 2, peptide 304-322 2mae Homo sapiens Eukaryo. plasma 1 0 3.7 ± 3.0 82 ± 0 -3.7
2.2.34.02. Huwentoxin-4 1mb6 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 4.4 ± 0.8 70 ± 12 -5.8
3.2.09.03. Tyrocidine A analogue AC3.28 6b35 Bacillus brevis Secreted 1 0 6.3 ± 1.6 79 ± 13 -10.1
2.4.15.01. Protein Nef 1avv Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.0 ± 1.5 75 ± 13 -3.4
3.1.07.05. Nonstructural protein 4b, segment 1751-1780 2jxf Hepatitis C virus Endoplasm. reticulum 1 0 5.6 ± 3.6 85 ± 2 -10.6
2.1.28.01. Heat-stable enterotoxin II 1ehs Escherichia coli Secreted 1 0 1.4 ± 1.1 64 ± 11 -6.0
3.4.12.01. Actinomycin Z3 1a7z Streptomyces antibioticus Secreted 1 0 10.0 ± 1.3 76 ± 24 -9.6
1.2.13.01. Intrinsic membrane protein PufX 2ita Rhodobacter sphaeroides Bact. Gram-neg inner 1 1 32.2 ± 5.1 33 ± 1 -22.8
2.1.10.01. Glycolipid transfer protein, conformation 1 1sx6 Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.1 85 ± 5 -10.1
2.4.10.01. Synapsin I 1auv Bos taurus Vesicle 1 0 1.9 ± 1.1 86 ± 11 -5.2
2.1.29.03. Apolipoprotein C-I, peptide 33-50 1ale Homo sapiens Secreted 1 0 4.9 ± 1.0 72 ± 4 -7.8
1.1.53.01. Integral Membrane Methyltransferase 4a2n Methanosarcina acetivorans Archaebac. 1 5 30.6 ± 1.2 10 ± 2 -58.3
1.2.44.01. Amyloid beta A4 protein (peptide 696-706) 1qcm Homo sapiens Eukaryo. plasma 1 0 2.6 ± 1.5 78 ± 17 -2.9
2.3.04.01. Tyrosine-protein phosphatase CpsB 2wje Streptococcus pneumoniae Bact. Gram-pos plas. 1 0 4.2 ± 2.8 76 ± 26 -4.6
2.1.01.01. Snake phospholipase A2, acidic 2, group I 1p7o Micropechis ikaheka Secreted 1 0 2.6 ± 0.5 90 ± 2 -9.4
1.2.39.02. Stromelysin-1 1c3i Homo sapiens Eukaryo. plasma 1 0 3.6 ± 1.7 85 ± 17 -4.4
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 4 3fps Oryctolagus cuniculus Endoplasm. reticulum 1 10 30.0 ± 0.9 16 ± 0 -53.5
2.2.34.01. Mu-O conotoxin MrVIB 1rmk Conus marmoreus Secreted 1 0 10.1 ± 1.3 62 ± 19 -10.7
3.2.01.08. Lactoferricin B, peptide 10-19 1y5c Bos taurus Secreted 1 0 2.2 ± 1.2 54 ± 11 -3.4
3.1.20.01. Alpha-conotoxin PIVA 1p1p Conus purpurascens (Purple cone) Secreted 1 0 2.4 ± 1.0 30 ± 11 -3.8
1.1.01.01. Bacteriorhodopsin-I 4pxk Haloarcula marismortui Archaebac. 1 7 31.8 ± 1.4 11 ± 1 -72.7
1.3.28.01. LPS-assembly protein complex, LptE and LptD 4n4r Salmonella typhimurium Bact. Gram-neg outer 1 26 23.4 ± 1.5 4 ± 0 -80.4
1.1.01.02. C-X-C chemokine receptor type 4, complex with peptide 4rws Homo sapiens Eukaryo. plasma 1 7 33.8 ± 1.5 9 ± 1 -76.9
3.4.02.03. Lantibiotic 107891 2mh5 Microbispora sp. Bact. Gram-pos plas. 1 0 7.3 ± 3.0 72 ± 38 -4.0
3.1.01.01. Varv peptide A/Kalata-B1 propeptide 1wn4 Viola odorata Secreted 1 0 6.4 ± 1.1 81 ± 14 -7.2
3.1.06.02. Amphipathic alpha-helix of apolipoprotein 2irg Designed proteins Undefined 1 0 6.4 ± 1.7 83 ± 15 -12.1
1.1.28.03. SecDF secretion protein, structure 2 5xan Deinococcus radiodurans Bact. Gram-neg inner 1 12 29.0 ± 1.6 5 ± 0 -99.8
1.2.32.01. Lanosterol 14-alpha demethylase (CYP51), with drug 4wmz Saccharomyces cerevisiae Endoplasm. reticulum 1 1 29.8 ± 0.7 39 ± 0 -36.1
2.2.39.01. Cardiotoxin II (cytotoxin II) 1ffj Naja naja oxiana Secreted 1 0 7.9 ± 0.8 56 ± 5 -13.7
2.2.60.01. Matrix protein VP40 1es6 Zaire ebolavirus Viral 1 0 2.1 ± 0.5 80 ± 3 -6.7
3.2.06.01. Paralytic peptide 2 1v28 Manduca sexta Secreted 1 0 2.9 ± 1.4 90 ± 16 -4.9
1.3.19.01. Porin OccAB2 5dl6 Acinetobacter baumannii Bact. Gram-neg outer 1 18 23.4 ± 1.4 4 ± 1 -59.1
1.1.01.02. Rhodopsin, complex with arrestin, structure 1 4zwj Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.1 9 ± 1 -78.7
2.2.12.01. Mite group 2 allergen Der f 2 1xwv Dermatophagoides farinae (American house dust mite) Secreted 1 0 1.2 ± 1.4 64 ± 10 -3.1
2.3.28.01. Aldo-keto reductase family 1 member C1 1qwk Caenorhabditis elegans Undefined 1 0 2.8 ± 1.0 66 ± 3 -6.3
1.1.69.01. HIG1 domain family member 1A 2lom Homo sapiens Eukaryo. plasma 1 2 22.0 ± 5.0 1 ± 1 -27.3
2.3.06.06. Type-B carboxylesterase/lipase 1cle Candida cylindracea Secreted 1 0 10.2 ± 0.0 83 ± 0 -24.7
3.1.15.01. Enterocin-HF 2n4k Enterococcus faecium Secreted 1 0 4.8 ± 3.5 82 ± 4 -4.8
2.2.07.03. Streptavidin 1mm9 Streptomyces avidinii Secreted 1 0 4.2 ± 1.6 56 ± 3 -8.4
2.1.05.02. Farnesyl diphosphate synthase (Geranyltranstransferase) 1rqj Escherichia coli Bact. Gram-neg inner 1 0 3.3 ± 0.7 87 ± 3 -7.7
2.4.16.01. Alpha-toxin CsE5 1nra Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.3 ± 1.2 89 ± 22 -4.3
3.1.05.11. ALPS-23 peptide 2m0w Designed proteins Undefined 1 0 5.7 ± 0.5 72 ± 6 -9.4
1.3.11.01. Autotransporter NalP 1uyn Neisseria meningitidis Bact. Gram-neg outer 1 12 25.3 ± 1.3 8 ± 8 -47.6
3.1.19.01. Trichotoxin a50e 1m24 Trichoderma viride Secreted 1 0 10.4 ± 1.8 75 ± 32 -14.3
2.2.34.07. Asteropsin E 2m3j Asteropus sp. Secreted 1 0 4.5 ± 1.1 65 ± 7 -3.6
1.1.33.01. Sodium bile acid symporter, outward-open conformation 1 4n7x Yersinia frederiksenii Bact. Gram-neg inner 1 10 28.6 ± 1.0 12 ± 0 -79.7
1.1.01.02. Beta-2 adrenergic receptor, active state, complex with antibody 3p0g Homo sapiens Eukaryo. plasma 1 7 30.1 ± 1.4 9 ± 1 -62.9
1.3.22.01. VDAC-1 channel, structure 1 2jk4 Homo sapiens Mitochon. outer 1 19 23.4 ± 2.3 0 ± 1 -40.0
2.2.41.01. Gallinacin-2 2lg5 Gallus gallus Secreted 1 0 8.0 ± 1.2 62 ± 6 -8.2
1.2.50.02. Nakanori protein 5h0q Grifola frondosa Eukaryo. plasma 1 0 0.9 ± 1.8 37 ± 15 -3.1
2.4.05.01. Sterol carrier protein 2 like domain of multifunctional enzyme type 2 1ikt Homo sapiens Peroxisome 1 0 3.5 ± 1.2 75 ± 17 -4.0
3.1.29.01. Cathelin-related peptide SC5 (SMAP-29) 1fry Ovis aries Secreted 1 0 1.1 ± 0.8 18 ± 9 -3.5
3.2.10.01. PawS derived peptide 10 2nb6 Designed proteins Undefined 1 0 9.9 ± 2.0 48 ± 30 -9.1
1.3.20.01. Outer membrane transporter FecA, different conformation 1kmp Escherichia coli Bact. Gram-neg outer 1 22 24.9 ± 0.9 4 ± 0 -74.0
1.1.15.01. Neuronal acetylcholine receptor, alpha-7 2maw Homo sapiens Eukaryo. plasma 1 4 30.0 ± 1.4 14 ± 1 -41.4
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1gym Bacillus cereus Secreted 1 0 4.9 ± 1.0 67 ± 11 -7.2
2.2.39.02. Mambalgin-1 5dz5 Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 6.2 ± 0.1 69 ± 1 -5.6
1.1.09.01. Zinc-transporting ATPase, ZntA, E2P state 4umv Shigella sonnei Bact. Gram-neg inner 1 8 30.6 ± 1.5 11 ± 2 -56.7
2.2.20.01. PH domain of pleckstrin homology domain-containing family A member 3 2mdx Homo sapiens Eukaryo. plasma 1 0 5.1 ± 1.1 11 ± 19 -4.1
1.2.32.01. Cytochrome P450 2B4, closed state 1 1suo Oryctolagus cuniculus Endoplasm. reticulum 1 0 4.6 ± 1.3 57 ± 4 -14.2
2.3.06.02. Antigen 85c, conformation 3 1dqy Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 5.1 ± 1.2 17 ± 3 -6.1
3.1.28.03. Maximin-4 2mhw Bombina maxima Secreted 1 0 4.4 ± 1.0 75 ± 3 -6.3
2.2.11.01. Rab3 interacting molecule 2 (RIM2), C2A domain 2bwq Rattus norvegicus Eukaryo. plasma 1 0 1.5 ± 1.6 41 ± 19 -1.8
1.1.01.02. Neurotensin receptor type 1, structure 4 5t04 Rattus norvegicus Eukaryo. plasma 1 7 31.4 ± 0.8 7 ± 1 -69.8
3.1.07.01. Fusion peptide (510-532) of protein gp41 2pjv Human immunodeficiency virus type 1 Endosome 1 0 8.7 ± 3.8 64 ± 4 -10.9
3.1.28.04. Phylloseptin-3 2jq1 Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 6.4 ± 0.8 74 ± 9 -9.5
2.2.06.02. Retinol-binding protein 2 2rcq Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 55 ± 6 -5.5
3.1.07.02. Juxtamembrane peptide (657-683) of protein gp160 2me1 Human immunodeficiency virus type 1 Endosome 1 0 7.7 ± 3.8 82 ± 1 -15.0
3.1.23.01. Meucin-24 2kfe Mesobuthus eupeus Secreted 1 0 4.3 ± 3.5 82 ± 2 -7.5
1.3.03.01. Outer membrane protein OprG 2x27 Pseudomonas aeruginosa Bact. Gram-neg outer 1 8 23.9 ± 1.7 7 ± 3 -39.6
2.4.01.01. Cholesterol oxidase 1coy Brevibacterium sterolicum Bact. Gram-pos plas. 1 0 4.4 ± 1.1 43 ± 10 -6.8
2.1.01.01. Snake phospholipase A2 2i0u Vipera nikolskii Secreted 1 0 5.6 ± 0.9 88 ± 9 -15.2
3.1.31.01. Dermcidin, structure 2 2ndk Homo sapiens Secreted 1 0 3.0 ± 2.0 86 ± 4 -9.6
1.1.26.07. Fumarate transporter 5da0 Deinococcus radiodurans Bact. Gram-neg inner 1 14 26.8 ± 0.7 13 ± 1 -78.2
1.2.24.01. Protein Vpu, cytoplasmic domain, structure in aqueous solution 1vpu Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.4 ± 2.1 64 ± 5 -5.6
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3g1q Trypanosoma brucei Endoplasm. reticulum 1 0 8.1 ± 1.5 62 ± 12 -10.8
2.1.01.01. Snake phospholipase A2, group II 1oz6 Echis carinatus Secreted 1 0 5.6 ± 1.0 84 ± 13 -9.6
3.1.15.01. Leucocin A, linear analogue 2ljt Leuconostoc gelidum Secreted 1 0 4.2 ± 2.8 81 ± 1 -6.6
1.1.25.06. Glucose transporter GLUT3/SLC2A3, outward-open 4zwc Homo sapiens Eukaryo. plasma 1 12 33.0 ± 1.3 6 ± 1 -93.2
3.1.03.02. Serine/threonine-protein kinase TOR1, FATC domain 2kit Saccharomyces cerevisiae Vacuole 1 0 6.3 ± 1.0 87 ± 18 -6.4
2.2.41.05. Crotamine 1z99 Crotalus durissus terrificus Secreted 1 0 3.7 ± 0.8 26 ± 5 -5.6
1.1.38.01. H+-driven MATE exporter, outward-open, "bent" conformation 3vvo Pyrococcus furiosus Archaebac. 1 12 31.4 ± 1.1 11 ± 0 -93.1
1.3.11.02. Invasin 4e1t Yersinia pseudotuberculosis Bact. Gram-neg outer 1 12 25.6 ± 1.4 9 ± 1 -51.0
2.3.06.12. Esterase LipW 3qh4 Mycobacterium marinum Bact. Gram-pos plas. 1 0 2.4 ± 1.2 76 ± 32 -5.0
2.1.03.01. Alpha-toxin (PHLC_CLOP1) 2wxu Clostridium perfringens Secreted 1 0 4.0 ± 0.9 85 ± 5 -7.0
2.2.34.06. Peptide jS3 5wxe Jasminum sambac Secreted 1 0 4.4 ± 1.2 48 ± 12 -6.0
3.1.02.12. Juxtamembrane peptide of epidermal growth factor receptor 1z9i Homo sapiens Eukaryo. plasma 1 0 4.7 ± 1.6 78 ± 5 -7.1
2.2.54.01. Non-structural protein 5A 3fqm Hepatitis C virus Endoplasm. reticulum 1 0 4.9 ± 1.1 77 ± 7 -7.5
3.2.05.02. Xanthomonin I 4nag Xanthomonas gardneri Secreted 1 0 8.7 ± 2.4 81 ± 11 -5.0
1.1.26.01. Leucine transporter LeuT, inward-facing conformation 3tt3 Aquifex aeolicus Bact. Gram-neg inner 1 12 27.4 ± 1.6 9 ± 0 -89.1
2.2.06.02. Myelin P2 protein 2wut Homo sapiens Eukaryo. plasma 1 0 4.1 ± 0.5 47 ± 7 -3.4
2.2.12.04. AP-2 complex 2vj0 Rattus norvegicus Vesicle 1 0 2.6 ± 2.0 80 ± 11 -4.8
2.2.34.01. Mu-conotoxin GS 1ag7 Conus geographus (Geography cone) Secreted 1 0 1.9 ± 1.0 68 ± 15 -2.6
1.1.64.01. Sodium/calcium exchanger, structure 2 3v5s Methanococcus jannaschii Archaebac. 1 10 29.6 ± 1.6 1 ± 2 -75.1
1.3.19.01. Porin OprE 4frx Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 22.0 ± 1.5 6 ± 0 -55.3
3.1.02.02. Sodium channel protein type 3 subunit alpha, TMH 2 1qg9 Rattus norvegicus Eukaryo. plasma 1 0 6.8 ± 0.4 86 ± 3 -9.0
2.1.01.01. Snake phospholipase A2, isoform 3 2osn Bungarus caeruleus Secreted 1 0 2.4 ± 0.6 84 ± 4 -5.8
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 3 3ksw Trypanosoma cruzi Endoplasm. reticulum 1 0 8.0 ± 6.7 61 ± 6 -9.1
2.2.34.04. Albumin 1 subunit B (Pab1) 1p8b Pisum sativum Secreted 1 0 11.1 ± 0.9 40 ± 13 -8.2
2.2.39.01. Weak tryptophan-containing neurotoxin 2mj0 Naja kaouthia Secreted 1 0 3.6 ± 1.7 57 ± 5 -5.9
3.1.01.03. Major prion protein, segment 1-30 1skh Bos taurus Eukaryo. plasma 1 1 20.8 ± 6.3 9 ± 5 -10.7
3.1.20.01. Alpha-conotoxin ImI 1e75 Conus imperialis (Imperial cone) Secreted 1 0 1.9 ± 0.9 80 ± 15 -3.7
1.2.04.01. Integrin alpha-X, cytoplasmic helix (peptide 1129-1163) 2luv Homo sapiens Eukaryo. plasma 1 0 4.0 ± 0.5 80 ± 7 -5.8
3.1.21.08. Moricin 2jr8 Manduca sexta Secreted 1 0 5.9 ± 1.6 75 ± 3 -11.5
3.1.05.09. Histidine-rich peptide LAH4 2kjn Designed proteins Undefined 1 0 10.5 ± 6.3 89 ± 2 -10.2
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form 4ors Homo sapiens Endoplasm. reticulum 1 0 2.6 ± 0.8 71 ± 7 -3.7
2.2.41.02. Antihypertensive protein BDS-1 1bds Anemonia sulcata Secreted 1 0 5.6 ± 0.8 83 ± 9 -9.6
2.3.06.01. Acetylcholinesterase 4qww Bungarus fasciatus Secreted 1 0 2.0 ± 1.5 36 ± 32 -3.0
2.1.21.02. Matrix protein p10, myristoylated, structure 2 2mxi Mason-Pfizer monkey virus Viral 1 0 3.8 ± 0.7 58 ± 3 -6.3
1.3.28.01. LPS-assembly protein complex, LptE and LptD 5iv9 Klebsiella pneumoniae Bact. Gram-neg outer 1 26 23.4 ± 1.0 3 ± 0 -81.0
1.1.25.06. Glucose transporter GLUT5, outward-open 4ybq Rattus norvegicus Eukaryo. plasma 1 12 32.4 ± 3.0 5 ± 0 -110.6
1.1.106.01. Phosphatidylglycerol phosphate phosphatase 5jki Bacillus subtilis Bact. Gram-pos plas. 1 6 28.6 ± 1.4 38 ± 0 -56.7
1.3.25.01. Leukocidin F 1pvl Staphylococcus aureus Secreted 1 0 4.0 ± 3.2 47 ± 10 -3.7
1.1.01.02. Adenosine receptor A2a, inactive state, with annular lipids 4eiy Homo sapiens Eukaryo. plasma 1 7 32.2 ± 1.2 18 ± 0 -70.4
1.2.32.01. Lanosterol 14-alpha demethylase 5jlc Candida glabrata Endoplasm. reticulum 1 1 29.8 ± 0.7 25 ± 1 -31.5
2.4.04.01. Sphingomyelinase C 1zwx Listeria ivanovii Secreted 1 0 6.2 ± 0.5 55 ± 1 -10.1
2.4.16.01. Tau-theraphotoxin-Hs1a 2n9z Haplopelma schmidti Secreted 1 0 6.1 ± 1.3 68 ± 10 -5.6
2.1.02.01. 8R-Lipoxygenase, complete structure 3dy5 Plexaura homomalla Eukaryo. plasma 1 0 2.3 ± 1.5 88 ± 10 -3.2
2.1.55.01. Secretion factor PAS 2b8i Vibrio vulnificus Secreted 1 0 5.4 ± 1.5 72 ± 7 -5.7
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 3 4jch Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.2 88 ± 1 -6.0
2.1.42.01. Bacteriocin 2fu2 Streptococcus pyogenes Secreted 1 0 1.6 ± 1.1 77 ± 16 -3.7
3.2.10.01. PawS derived peptide 5 2lwt Designed proteins Undefined 1 0 8.1 ± 2.2 55 ± 21 -5.2
3.2.03.01. Hepcidin, structure 2 1m4f Homo sapiens Secreted 1 0 5.9 ± 1.2 76 ± 18 -6.4
3.1.18.02. Phenol-soluble modulin alpha-1 5khb Staphylococcus aureus Secreted 1 0 9.4 ± 0.8 71 ± 4 -12.7
2.3.14.01. Retinaldehyde-binding protein 1, closed state, more complete structure 3hy5 Homo sapiens Eukaryo. plasma 1 0 2.0 ± 3.9 55 ± 17 -4.5
1.2.22.02. BH3-interacting domain death agonist 2m5i Homo sapiens Mitochon. outer 1 0 6.4 ± 1.5 86 ± 0 -18.8
2.1.60.01. Aurelin 2lg4 Aurelia aurita Secreted 1 0 2.0 ± 0.9 50 ± 6 -4.4
2.1.18.01. Annexin V 1yii Gallus gallus Eukaryo. plasma 1 0 3.1 ± 0.7 79 ± 7 -5.1
2.3.12.01. Myotubularin-related protein 2, monomer 1zvr Homo sapiens Endosome 1 0 3.1 ± 0.4 89 ± 8 -5.0
2.2.41.04. Antimicrobial peptide LCI 2b9k Bacillus subtilis Secreted 1 0 1.6 ± 2.9 89 ± 19 -4.4
3.1.05.03. GLFDIVKKVVGALG 5mxl Designed proteins Undefined 1 0 5.0 ± 0.4 86 ± 6 -7.8
1.1.100.01. Voltage-sensor domain of phosphatase, conformation 2 4g7v Ciona intestinalis Eukaryo. plasma 1 4 30.2 ± 1.8 5 ± 0 -49.2
1.2.32.01. Plant cytochrome P450 74A (allene oxide synthase) 3dsk Arabidopsis thaliana Thylakoid 1 0 5.7 ± 0.5 67 ± 3 -20.0
2.2.06.01. Retinol binding protein, plasma isoform 1iiu Gallus gallus Secreted 1 0 1.9 ± 1.8 35 ± 17 -4.4
3.1.21.02. Decoralin 2n9a Oreumenes decoratus Secreted 1 0 6.7 ± 1.7 86 ± 11 -8.9
2.2.20.01. Oxysterol-binding protein-related protein 8 5u78 Homo sapiens Eukaryo. plasma 1 0 3.6 ± 1.2 71 ± 5 -6.9
1.2.32.01. Cytochrome P450 2D6, conformation 4 4xry Homo sapiens Endoplasm. reticulum 1 0 8.8 ± 3.0 41 ± 2 -15.5
2.4.16.01. Toxin CsEv3 2sn3 Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.3 74 ± 17 -5.5
3.1.20.01. O2-contryphan-Vc2 5l34 Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.4 85 ± 8 -4.2
1.2.03.02. T-cell immunoglobulin and mucin domain-containing protein 4 3bib Mus musculus Eukaryo. plasma 1 0 3.2 ± 1.9 41 ± 7 -4.6
1.2.32.01. Cytochrome P450 2D6, conformation 1 2f9q Homo sapiens Endoplasm. reticulum 1 0 7.0 ± 1.8 29 ± 10 -12.0
2.2.20.01. Phosphoinositol 3-phosphate binding protein 1 1upr Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.4 62 ± 19 -3.6
3.1.07.02. Juxtamembrane peptide (671-697) of protein gp160 2me4 Human immunodeficiency virus type 1 Endosome 1 0 7.9 ± 2.9 81 ± 4 -14.0
2.1.19.01. Antifungal peptide 2l2r Echinochloa crus-galli Secreted 1 0 3.4 ± 1.5 50 ± 8 -3.8
2.2.45.01. Outer membrane protein IcsA autotransporter 3ml3 Shigella flexneri Bact. Gram-neg outer 1 0 3.4 ± 0.5 65 ± 2 -6.2
1.2.25.02. Na,K-ATPase regulatory protein FXYD2 2mkv Homo sapiens Eukaryo. plasma 1 1 30.6 ± 3.0 23 ± 2 -25.9
1.2.38.01. Penicillin-binding protein 2 2olv Staphylococcus aureus Bact. Gram-pos plas. 1 0 3.7 ± 2.0 58 ± 8 -7.3
2.1.24.01. Pulmonary surfactant-associated protein B fragments 2dwf Homo sapiens Secreted 1 0 5.6 ± 1.3 77 ± 4 -9.5
2.3.06.19. Thermostable lipase 5h6b Streptomyces sp. Secreted 1 0 4.4 ± 0.8 58 ± 41 -8.2
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, delta isoform 2wxf Mus musculus Eukaryo. plasma 1 0 2.3 ± 1.8 89 ± 3 -5.3
2.4.06.01. Acyl-coenzyme A thioesterase 11 3fo5 Homo sapiens Endoplasm. reticulum 1 0 2.3 ± 1.4 57 ± 7 -3.9
2.1.01.01. Phospholipase A2, group IIA 1n28 Homo sapiens Secreted 1 0 3.6 ± 0.6 88 ± 4 -7.0
3.4.01.01. Contryphan-In 2m6d Conus inscriptus Secreted 1 0 8.2 ± 1.0 57 ± 15 -5.8
1.2.17.02. Synaptobrevin homolog 1 1iou Saccharomyces cerevisiae Eukaryo. plasma 1 0 3.4 ± 1.1 79 ± 12 -6.0
1.1.01.03. Glucagon receptor, full-length, structure 1 5xez Homo sapiens Eukaryo. plasma 1 7 30.6 ± 1.0 12 ± 1 -55.2
3.1.33.01. Stage V sporulation protein M 2mvh Bacillus subtilis Vacuole 1 0 6.3 ± 1.0 90 ± 4 -9.9
3.1.11.02. Pituitary adenylate cyclase activating polypeptide (PACAP)-38 2d2p Homo sapiens Secreted 1 0 3.9 ± 4.0 90 ± 0 -6.8
1.3.01.01. Outer membrane protein A (OMPA) 1bxw Escherichia coli Bact. Gram-neg outer 1 8 25.4 ± 1.9 5 ± 1 -35.6
1.1.01.02. Opsin, complex with arrestin peptide 4pxf Bos taurus Eukaryo. plasma 1 7 31.6 ± 0.9 8 ± 1 -80.1
3.1.26.01. Piscidin 1 2ojm Morone saxatilis Secreted 1 0 10.6 ± 1.0 82 ± 13 -16.3
2.3.06.04. Palmitoyl protein thioesterase 1 1eh5 Bos taurus Lysosome 1 0 5.3 ± 0.9 59 ± 6 -8.1
1.2.42.01. UDP-2,3-diacylglucosamine hydrolase, lpxH 5k8k Haemophilus influenzae Bact. Gram-neg inner 1 0 9.3 ± 1.8 13 ± 7 -8.7
3.1.07.08. Peptide of outer capsid glycoprotein VP7 (266-326) 2lm7 Rotavirus A Endoplasm. reticulum 1 0 10.2 ± 1.5 76 ± 0 -13.6
2.2.34.11. Kalata B1, segment 93-120 1nb1 Oldenlandia affinis Secreted 1 0 5.3 ± 1.4 81 ± 18 -5.5
2.1.60.03. Pseudecin, conformation 2 2epf Pseudechis porphyriacus Secreted 1 0 5.4 ± 1.1 86 ± 1 -4.6
1.1.49.01. ATP-dependent zinc metalloprotease FtsH 1lv7 Escherichia coli Bact. Gram-neg inner 1 0 2.1 ± 1.0 80 ± 11 -4.3
2.4.03.01. Tubby protein, ligand-free 1c8z Mus musculus Eukaryo. plasma 1 0 2.8 ± 0.9 89 ± 13 -5.8
1.1.12.14. TRPV6 channel, monomer, structure 2 5woa Rattus norvegicus Eukaryo. plasma 1 6 30.2 ± 1.6 12 ± 6 -85.2
2.2.34.02. Delta-amaurobitoxin-Pl1b 1v91 Pireneitega luctuosa (Tangled nest spider) Secreted 1 0 2.4 ± 0.9 35 ± 4 -5.7
1.3.17.02. Outer membrane protein assembly factor BamA 4n75 Escherichia coli Bact. Gram-neg outer 1 16 23.8 ± 0.8 11 ± 0 -61.1
1.1.25.05. Proton-dependent oligopeptide transporter, conformation 3 4ikx Geobacillus kaustophilus Bact. Gram-pos plas. 1 14 31.0 ± 1.0 10 ± 0 -115.9
2.3.06.09. Cutinase 1 3dcn Colletotrichum gloeosporioides Secreted 1 0 5.7 ± 1.2 44 ± 8 -10.1
2.4.04.01. Type II inositol-1,4,5-trisphosphate 5-phosphatase 3n9v Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.4 63 ± 6 -6.0
2.2.20.01. PH domain of oxysterol-binding protein homolog 3, fused with lysozyme 4iap Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.5 ± 2.3 81 ± 3 -3.6
2.4.16.02. Sapecin 1l4v Sarcophaga peregrina Secreted 1 0 5.4 ± 1.5 84 ± 18 -5.1
3.1.29.01. Fowlicidin-2 2gdl Gallus gallus Secreted 1 0 3.1 ± 0.5 85 ± 4 -8.9
2.2.20.03. Radixin 1gc6 Mus musculus Eukaryo. plasma 1 0 15.4 ± 1.8 17 ± 12 -17.9
1.1.10.08. Multidrug resistance protein 1 6c0v Homo sapiens Eukaryo. plasma 1 12 32.6 ± 1.2 5 ± 0 -105.0
2.1.21.02. Matrix protein p10, myristoylated, structure 1 2lpy Mason-Pfizer monkey virus Viral 1 0 3.2 ± 0.5 8 ± 6 -3.4
3.1.11.01. Neuropeptide F 1k8v Moniezia expansa (Sheep tapeworm) Secreted 1 0 2.9 ± 1.1 68 ± 9 -7.0
1.3.20.01. Bacterial Zn-transporter ZnuD, structure 2 4rdt Neisseria meningitidis Bact. Gram-neg outer 1 22 23.4 ± 0.8 0 ± 0 -72.6
2.4.29.01. Superantigen-like protein 3r2t Staphylococcus aureus Undefined 1 0 4.2 ± 0.0 79 ± 1 -6.2
1.1.110.01. Apolipoprotein N-acyl transferase, structure 4 5xhq Escherichia coli Bact. Gram-neg inner 1 8 29.4 ± 1.2 13 ± 2 -70.1
1.1.01.02. Muscarinic acetylcholine receptor M3, structure 1 4daj Rattus norvegicus Eukaryo. plasma 1 7 32.2 ± 1.2 5 ± 0 -75.8
1.1.95.01. Acyl-CoA desaturase 4zyo Homo sapiens Endoplasm. reticulum 1 4 29.2 ± 2.4 3 ± 1 -59.1
2.3.06.03. Gastric lipase, closed state 1hlg Homo sapiens Secreted 1 0 3.2 ± 1.4 6 ± 12 -5.6
2.3.06.01. Carboxylic ester hydrolase, closed state 4be4 Ophiostoma piceae Secreted 1 0 6.4 ± 2.3 61 ± 4 -5.7
2.2.11.01. Synaptotagmin-1 C2A-C2B domains 2r83 Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.9 89 ± 10 -3.8
1.2.32.01. Cytochrome P450 24a1 (1,25-dihydroxyvitamin D(3) 24-hydroxylase) 3k9v Rattus norvegicus Mitochon. inner 1 0 6.6 ± 1.0 49 ± 6 -9.6
1.2.43.01. Envelope glycoprotein, West Nile virus, structure 3 3i50 West Nile virus Viral 1 0 6.3 ± 2.8 27 ± 19 -4.4
1.3.20.01. SusD-SusC complex 5t3r Bacteroides thetaiotaomicron Bact. Gram-neg outer 1 22 25.0 ± 0.6 3 ± 0 -78.5
2.3.14.01. Phosphatidylinositol transfer protein sec14p 1aua Saccharomyces cerevisiae Golgi 1 0 8.8 ± 1.1 75 ± 10 -14.3
2.4.11.01. Beta-hordothionin 1wuw Hordeum vulgare Secreted 1 0 3.6 ± 1.1 55 ± 15 -5.4
1.1.101.01. Oxidoreductase CcdA, outward-facing structure 5vkv Thermus thermophilus Bact. Gram-neg inner 1 6 31.4 ± 1.0 21 ± 0 -85.2
1.1.01.02. Thrombin (proteinase-activated) receptor 1, PAR1 3vw7 Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.9 1 ± 0 -72.2
3.1.17.01. Antimicrobial peptide HP 1p0l Helicobacter pylori Secreted 1 0 5.3 ± 0.6 79 ± 9 -10.5
3.1.11.02. Exendin-4-conotoxin chimera 2naw Designed proteins Secreted 1 0 4.3 ± 1.4 69 ± 8 -2.7
2.2.11.01. Synaptotagmin-17 2enp Homo sapiens Eukaryo. plasma 1 0 4.6 ± 1.5 6 ± 14 -4.9
1.1.34.01. Mitochondrial ADP-ATP carrier, conformation 2 4c9q Saccharomyces cerevisiae Mitochon. inner 1 6 30.2 ± 1.1 4 ± 1 -57.7
1.2.22.01. Apoptosis regulator Bcl-2 1g5m Homo sapiens Mitochon. outer 1 0 4.2 ± 1.4 33 ± 11 -6.6
2.1.14.02. SusD superfamily protein 3myv Bacteroides vulgatus Secreted 1 0 4.0 ± 1.0 64 ± 2 -6.0
1.1.63.01. Type 1 signal peptidase, complex with inhibitor 1b12 Escherichia coli Bact. Gram-neg inner 1 0 5.4 ± 1.8 88 ± 7 -5.1
2.2.14.01. C2 domain of coagulation factor V 1czs Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.6 13 ± 15 -6.2
1.1.117.01. DHHC20 palmitoyltransferase, structure 1 6bml Homo sapiens Golgi 1 4 29.0 ± 2.6 29 ± 1 -52.1
2.2.41.01. Neutrophil defensin 1 2pm1 Homo sapiens Secreted 1 0 3.6 ± 1.3 85 ± 6 -3.8
3.1.11.02. Glucagon-like peptide-1 receptor agonists 2n08 Designed proteins Undefined 1 0 6.3 ± 1.3 45 ± 10 -5.4
1.3.07.01. Outer membrane protease OmpT 1i78 Escherichia coli Bact. Gram-neg outer 1 10 26.5 ± 1.6 5 ± 6 -46.9
1.1.26.01. Dopamine transporter, outward-facing conformation 4m48 Drosophila melanogaster Eukaryo. plasma 1 12 30.8 ± 1.6 12 ± 0 -101.0
3.4.02.02. Mersacidin, structure in methanol solution 1mqx Bacillus sp. Secreted 1 0 1.9 ± 1.3 87 ± 15 -2.9
1.2.39.02. Matrilysin, structure 1 2mze Homo sapiens Secreted 1 0 3.3 ± 0.9 68 ± 2 -8.0
1.1.56.01. Steryl-sulfatase 1p49 Homo sapiens Endoplasm. reticulum 1 2 29.6 ± 1.1 23 ± 0 -34.6
3.1.19.01. Paracelsin X 4by8 Trichoderma reesei Secreted 1 0 14.6 ± 5.1 60 ± 4 -14.6
1.1.01.03. Glucagon receptor, structure 2 5ee7 Homo sapiens Eukaryo. plasma 1 7 31.4 ± 1.4 19 ± 3 -66.2
2.2.26.01. RUN and FYVE domain-containing protein 1 2yw8 Homo sapiens Endosome 1 0 0.7 ± 3.4 48 ± 38 -2.8
2.4.16.02. Phormicin 1ica Protophormia terraenovae (Northern blowfly) Secreted 1 0 3.7 ± 2.3 90 ± 23 -5.0
1.2.38.03. Endo-type membrane-bound lytic murein transglycosylase A 2y8p Escherichia coli Bact. Gram-neg outer 1 0 0.0 ± 3.6 86 ± 15 -2.2
2.1.10.01. Accelerated-cell-death 11 protein, complex with lipid 4nti Arabidopsis thaliana Eukaryo. plasma 1 0 5.7 ± 0.5 80 ± 2 -10.7
2.2.34.06. Tripatide 2mfs Trichocereus pachanoi Thylakoid 1 0 4.1 ± 0.8 81 ± 6 -7.6
2.4.11.01. Viscotoxin A3 1okh Viscum album Secreted 1 0 4.6 ± 1.3 32 ± 19 -4.9
3.1.28.04. Phylloseptin-1 2jq0 Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 9.5 ± 1.4 76 ± 7 -13.5
1.3.20.01. Outer membrane cobalamin transporter BtuB, complex with colicin E2 R-domain 2ysu Escherichia coli Bact. Gram-neg outer 1 22 24.2 ± 1.0 5 ± 0 -75.2
2.2.11.01. Protein kinase C eta, C2 domain 2fk9 Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.1 57 ± 6 -5.0
2.2.08.01. Osmotin 1pcv Nicotiana tabacum Secreted 1 0 2.4 ± 1.9 82 ± 19 -2.7
3.1.28.09. Pseudin-2, structure 1 2ncy Pseudis paradoxa Secreted 1 0 4.9 ± 3.0 77 ± 5 -5.8
1.1.25.07. Nitrate/nitrite exchanger NarK, occluded state 4u4w Escherichia coli Bact. Gram-neg inner 1 12 30.0 ± 1.4 10 ± 1 -91.0
3.1.02.05. Acetylcholine receptor, subunit beta2, TMH 2 2k59 Homo sapiens Eukaryo. plasma 1 1 30.2 ± 1.9 20 ± 4 -21.0
1.2.32.01. Cytochrome P450 1A2 2hi4 Homo sapiens Endoplasm. reticulum 1 0 6.9 ± 1.0 66 ± 9 -16.2
2.1.01.01. Snake phospholipase A2, group I, acidic 2 1m8t Ophiophagus hannah Secreted 1 0 4.4 ± 0.8 88 ± 6 -6.6
1.2.55.01. Neutral ceramidase, structure 2 2zxc Pseudomonas aeruginosa Secreted 1 0 4.6 ± 1.7 71 ± 8 -7.6
2.2.06.02. Fatty acid-binding protein 1ftp Schistocerca gregaria Eukaryo. plasma 1 0 4.5 ± 1.0 53 ± 11 -5.2
3.1.07.01. Fusion peptide of protein gp41, hybrid sequences 5nvp Human immunodeficiency virus type 1 Endosome 1 0 3.9 ± 2.0 68 ± 6 -8.1
3.4.02.06. Epilancin 15X 1w9n Staphylococcus epidermidis Secreted 1 0 2.9 ± 1.0 72 ± 7 -5.0
1.1.01.01. Sensory rhodopsin II, monomer 1h68 Natronomonas pharaonis Archaebac. 1 7 30.3 ± 1.5 15 ± 2 -60.0
2.1.08.01. Quinohemoprotein alcohol dehydrogenase ADH IIB 1kv9 Pseudomonas putida Bact. Gram-neg outer 1 0 1.7 ± 1.1 77 ± 22 -5.9
1.1.01.02. Free fatty acid receptor 1, structure 1 4phu Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 10 ± 1 -59.2
1.1.39.01. Riboflavin transporter RibU 3p5n Staphylococcus aureus Bact. Gram-pos plas. 1 6 30.6 ± 1.4 6 ± 4 -53.5
3.2.02.02. T-2-conotoxin MrIA 2ew4 Conus marmoreus Secreted 1 0 2.5 ± 1.5 81 ± 19 -3.0
2.2.39.01. Cytotoxin-1, in micelles 5nq4 Naja naja oxiana Secreted 1 0 7.9 ± 7.9 55 ± 7 -12.9
2.4.15.01. Protein Nef (HIV 9HIV1) 2xi1 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 4.3 ± 0.6 57 ± 5 -5.0
3.1.09.01. ICP47 protein, active domain (1-34) 1qlo Human herpesvirus Endoplasm. reticulum 1 0 8.6 ± 0.8 58 ± 8 -10.2
2.2.06.01. Epididymal-specific lipocalin-5 1epb Rattus norvegicus Secreted 1 0 6.4 ± 1.1 74 ± 4 -3.8
3.4.12.01. Actinomycin X2 1qfi Streptomyces antibioticus Secreted 1 0 15.2 ± 2.3 35 ± 34 -14.1
1.1.02.05. Light-harvesting protein B-870, beta chain 1wrg Rhodospirillum rubrum Bact. Gram-neg inner 1 1 27.0 ± 4.7 44 ± 1 -23.9
2.3.08.02. Cytosolic phospholipase A2, group IVA 1cjy Homo sapiens Vesicle 1 0 5.8 ± 1.0 70 ± 9 -9.9
2.4.17.01. Vitellogenin 1lsh Ichthyomyzon unicuspus (Silver lamprey) Secreted 1 0 3.4 ± 1.3 81 ± 0 -4.6
2.2.09.03. Surface layer protein 1l0q Methanosarcina mazei (Methanosarcina frisia) Archaebac. 1 0 3.1 ± 0.9 81 ± 7 -5.1
1.3.17.01. Filamentous hemagglutinin transporter FhaC, structure 1 3njt Bordetella pertussis Bact. Gram-neg outer 1 16 23.6 ± 0.9 7 ± 0 -65.8
2.2.06.02. Fatty acid-binding protein, epidermal 4azp Mus musculus Eukaryo. plasma 1 0 4.2 ± 2.4 57 ± 11 -5.5
2.1.01.01. Snake phospholipase A2, acidic, group II 1ijl Agkistrodon acutus Secreted 1 0 4.2 ± 1.2 83 ± 12 -7.5
2.1.24.01. Saposin A (peptide 60-140), conformation in disc 4ddj Homo sapiens Lysosome 1 0 6.4 ± 0.9 89 ± 3 -8.5
1.1.37.01. Divalent metal cation transporter MntH 5kte Deinococcus radiodurans Bact. Gram-neg inner 1 11 29.8 ± 0.8 7 ± 1 -63.3
2.4.33.01. 72 kDa type IV collagenase, 32-452 1eak Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.6 37 ± 6 -6.6
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 5 1kju Oryctolagus cuniculus Endoplasm. reticulum 1 10 33.8 ± 0.2 26 ± 1 -68.6
2.2.34.02. omega-Agatoxin 1agg Agelenopsis aperta Secreted 1 0 2.5 ± 1.4 57 ± 17 -5.0
3.1.11.01. Neuropeptide Y analogue 1icy Sus scrofa Secreted 1 0 6.4 ± 0.5 69 ± 6 -8.1
3.1.20.01. Alpha-conotoxin EIVA 1pqr Conus ermineus Secreted 1 0 2.5 ± 1.3 14 ± 14 -3.4
1.3.03.01. Outer membrane protein W, NMR model 2mhl Escherichia coli Bact. Gram-neg outer 1 8 23.4 ± 1.8 17 ± 0 -25.7
2.2.11.01. Synaptotagmin-1, C2B domain (Calcium-bound) 4v11 Homo sapiens Eukaryo. plasma 1 0 1.6 ± 2.3 40 ± 7 -3.2
2.2.34.11. Vodo peptide N 2aks Viola odorata Secreted 1 0 4.0 ± 1.4 89 ± 22 -6.7
1.1.28.03. SecDF secretion protein, structure 3 5xap Deinococcus radiodurans Bact. Gram-neg inner 1 12 30.2 ± 0.8 2 ± 1 -97.2
1.2.07.01. Protein jagged-1 2vj2 Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.8 84 ± 8 -5.8
2.2.39.01. Cardiotoxin III (cytotoxin 3) 1h0j Naja atra Secreted 1 0 7.1 ± 0.9 59 ± 7 -11.3
1.1.34.01. Mitochondrial ADP-ATP carrier 1okc Bos taurus Mitochon. inner 1 6 29.5 ± 1.7 14 ± 1 -44.6
3.2.06.01. Growth-blocking peptide 2djc Spodoptera litura Secreted 1 0 2.9 ± 2.0 19 ± 14 -3.1
1.3.19.01. Porin OccAB3 5dl7 Acinetobacter baumannii Bact. Gram-neg outer 1 18 23.0 ± 1.2 4 ± 0 -62.1
1.1.01.02. Neurotensin receptor type 1, structure 3 4xes Rattus norvegicus Eukaryo. plasma 1 7 31.8 ± 1.4 5 ± 1 -68.3
2.2.12.01. Lymphocyte antigen 86 3mtx Gallus gallus Secreted 1 0 2.3 ± 1.6 69 ± 11 -2.4
2.3.28.01. Aldo-keto reductase family 1 member C21 3fjn Mus musculus Undefined 1 0 2.8 ± 1.0 56 ± 3 -5.2
1.1.69.01. HIG1 domain family member 1B 2lon Homo sapiens Eukaryo. plasma 1 2 22.4 ± 1.2 19 ± 0 -13.7
2.3.06.19. Lipase A 1isp Bacillus subtilis Secreted 1 0 1.9 ± 0.8 59 ± 12 -5.2
2.3.01.06. Glycosyl hydrolase PslG 5bxa Pseudomonas aeruginosa Secreted 1 0 6.0 ± 1.2 72 ± 9 -6.9
1.2.33.02. Protoporphyrinogen oxidase 2ivd Myxococcus xanthus Bact. Gram-neg inner 1 0 3.7 ± 0.2 29 ± 2 -8.0
2.1.52.01. Pheromone binding protein 1ow4 Rhyparobia maderae (Madeira cockroach) Secreted 1 0 4.4 ± 0.8 30 ± 16 -4.4
2.2.05.01. Amicyanin 1sfd Paracoccus denitrificans Bact. Gram-neg inner 1 0 3.5 ± 0.8 49 ± 10 -4.0
1.3.20.01. Pyoverdine Outer Membrane Receptor FpvA, with Pyocin-S2 5odw Pseudomonas aeruginosa Bact. Gram-neg outer 1 22 23.8 ± 0.6 5 ± 0 -71.4
2.1.15.02. ADP-ribosylation factor-binding protein GGA2 1mhq Homo sapiens Golgi 1 0 4.2 ± 1.2 74 ± 5 -4.1
2.4.16.01. Alpha-mammal toxin BmK-M8 1snb Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.4 ± 2.4 79 ± 22 -2.3
2.4.11.01. Crambin, enantiomer 3ue7 Designed proteins Undefined 1 0 3.4 ± 1.7 89 ± 13 -4.6
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, more complete 4ezk Homo sapiens Eukaryo. plasma 1 0 3.6 ± 0.6 81 ± 2 -5.1
1.2.32.01. Cytochrome P450 2C9, structure 3 5w0c Homo sapiens Endoplasm. reticulum 1 0 2.5 ± 3.0 43 ± 3 -5.0
3.1.19.01. Cephaibol A 1ob4 Acremonium tubakii Secreted 1 0 14.1 ± 2.5 58 ± 18 -14.7
2.2.34.06. Peptide jS1 2n5q Jasminum sambac Secreted 1 0 3.8 ± 1.2 71 ± 15 -6.1
1.1.01.02. Rhodopsin, active (metarhodopsin II), complex with peptide of transducin 3pqr Bos taurus Eukaryo. plasma 1 7 31.8 ± 1.1 9 ± 1 -78.3
1.3.22.01. VDAC-1 channel 3emn Mus musculus Mitochon. outer 1 19 23.4 ± 1.1 5 ± 1 -52.5
2.4.05.01. Sterol carrier protein 2 2cx7 Thermus thermophilus Bact. Gram-neg inner 1 0 4.7 ± 1.3 73 ± 13 -6.9
2.1.14.01. Peroxisomal targeting signal 1 receptor 1fch Homo sapiens Peroxisome 1 0 6.9 ± 1.2 54 ± 3 -6.7
3.2.01.07. Protegrin-1 1pg1 Sus scrofa Secreted 1 0 2.2 ± 0.4 72 ± 4 -4.2
3.2.10.01. PawS derived peptide 9 2nb5 Designed proteins Undefined 1 0 5.6 ± 1.3 79 ± 14 -6.5
1.3.11.01. Autotransporter NalP, different conformation 1uyo Neisseria meningitidis Bact. Gram-neg outer 1 12 23.6 ± 1.4 8 ± 0 -42.7
1.1.10.04. P-glycoprotein, inward-facing conformation 1c 4m1m Mus musculus Eukaryo. plasma 1 12 31.2 ± 1.3 2 ± 1 -90.6
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1aod Listeria monocytogenes Secreted 1 0 7.4 ± 1.0 79 ± 10 -9.2
2.2.39.02. Mambalgin-2 2mfa Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 2.7 ± 2.5 76 ± 5 -6.4
1.1.09.01. Zinc-transporting ATPase, ZntA, E2.PI state 4umw Shigella sonnei Bact. Gram-neg inner 1 8 31.0 ± 1.2 19 ± 2 -65.9
1.2.32.01. Cytochrome P450 2C8 1pq2 Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 1.8 65 ± 9 -8.6
2.3.06.02. Antigen 85c, conformation 4 5vns Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 2.7 ± 1.2 33 ± 2 -8.4
3.1.28.06. Magainin 2, Ala-analogue 4mgp Designed proteins Secreted 1 0 10.0 ± 4.1 79 ± 2 -15.1
3.4.13.01. T-cell-specific surface glycoprotein CD28, intracellular loop 2nae Mus musculus Eukaryo. plasma 1 0 0.9 ± 10.0 81 ± 3 -6.4
3.1.07.02. Juxtamembrane peptide (662-683) of protein gp41 2pv6 Human immunodeficiency virus type 1 Endosome 1 0 6.7 ± 0.6 82 ± 2 -13.5
1.1.15.01. Nicotinic acetylcholine receptor, beta-2, in hexafluoroisopropanol/water 2ksr Homo sapiens Eukaryo. plasma 1 4 29.1 ± 2.2 16 ± 1 -47.0
3.1.07.01. Probable fusion peptide (93-126, 138-160) of protein gp41 2mk3 Human immunodeficiency virus type 1 Endosome 1 2 20.8 ± 0.5 18 ± 1 -13.2
2.4.16.03. Chlorotoxin 1chl Leiurus quinquestriatus quinquestriatus Secreted 1 0 6.5 ± 1.2 87 ± 14 -4.3
1.1.01.02. P2Y purinoceptor 12, structure 1 4ntj Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 9 ± 0 -79.8
2.3.06.07. Thermostable lipase 2dsn Geobacillus zalihae Secreted 1 0 4.9 ± 0.9 32 ± 3 -7.7
2.2.61.01. Effector protein PevD1 5xmz Verticillium dahliae Secreted 1 0 3.5 ± 0.8 33 ± 2 -5.6
1.1.26.07. STAS domain of anion permease 3oiz Rhodobacter sphaeroides Bact. Gram-neg inner 1 0 3.9 ± 0.4 18 ± 5 -5.4
3.1.04.03. Viral protein R, peptide 59-86 1dsk Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 9.5 ± 0.4 65 ± 6 -11.7
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 1 2wuz Trypanosoma cruzi Endoplasm. reticulum 1 0 4.0 ± 1.1 75 ± 11 -9.9
2.1.01.01. Snake phospholipase A2, group I, isoform 2 1u4j Bungarus caeruleus Secreted 1 0 2.2 ± 0.6 83 ± 4 -8.5
2.4.16.02. Lucifensin 2lld Lucilia sericata Secreted 1 0 1.1 ± 1.7 11 ± 12 -3.0
2.3.02.01. Phospholipase C-delta isoform 1 1djx Rattus norvegicus Eukaryo. plasma 1 0 4.1 ± 0.9 68 ± 5 -7.2
1.1.01.03. Calcitonin receptor-Gs protein complex 5uz7 Homo sapiens Eukaryo. plasma 1 7 30.2 ± 1.0 13 ± 0 -50.9
3.1.02.04. V-type proton ATPase subunit a, vacuolar isoform, TMH 7 2jtw Saccharomyces cerevisiae Vacuole 1 1 20.8 ± 6.5 8 ± 7 -7.7
1.1.38.01. H+-driven MATE exporter, outward-open, with nonpeptide inhibitor 3vvp Pyrococcus furiosus Archaebac. 1 12 29.8 ± 1.3 8 ± 0 -79.6
1.3.20.01. Pesticin receptor FyuA 4epa Yersinia pestis Bact. Gram-neg outer 1 22 23.6 ± 0.8 3 ± 0 -73.5
2.1.03.01. Alpha-toxin (PHLC_CLOP1) , different conformation 1qmd Clostridium perfringens Secreted 1 0 4.8 ± 1.0 80 ± 8 -6.7
2.1.01.01. Phospholipase A2, group IIE 5wzm Homo sapiens Secreted 1 0 2.0 ± 2.0 88 ± 2 -6.6
3.1.03.04. Anchor helix of protein yopD (peptide 278-300) 1kdl Yersinia pseudotuberculosis Eukaryo. plasma 1 0 5.7 ± 0.8 86 ± 12 -5.0
1.2.32.01. Steroid 21-hydroxylase (P450 C21) 3qz1 Bos taurus Endoplasm. reticulum 1 0 5.9 ± 1.6 72 ± 3 -10.4
2.2.06.01. Retinol binding protein 1kt6 Bos taurus Secreted 1 0 4.3 ± 1.7 74 ± 12 -4.7
2.2.20.01. PH domain of 3-phosphoinositide-dependent protein kinase 1 1w1g Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 20 ± 18 -4.8
1.2.17.02. Synaptobrevin homolog YKT6 3kyq Rattus norvegicus Vesicle 1 0 2.5 ± 2.0 53 ± 8 -4.9
2.2.34.01. Conotoxin TVIIA 1eyo Conus tulipa (Fish-hunting cone snail) Secreted 1 0 2.2 ± 0.7 74 ± 9 -4.6
1.3.19.01. Porin OpdN 4fso Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 21.8 ± 2.2 7 ± 1 -61.3
3.1.02.02. S5P linker peptide (570-611) of HERG K+ channel 1ujl Homo sapiens Eukaryo. plasma 1 0 4.6 ± 0.3 89 ± 7 -7.6
2.1.01.01. Snake phospholipase A2, acidic 2h4c Daboia russellii siamensis Secreted 1 0 5.7 ± 1.1 88 ± 10 -9.0
1.2.03.02. T-cell-specific surface glycoprotein CD28 1yjd Homo sapiens Eukaryo. plasma 1 0 4.5 ± 0.6 46 ± 11 -3.6
1.2.32.01. Cytochrome P450 2B4, closed state 2 2q6n Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.5 ± 0.4 55 ± 2 -13.0
2.4.16.01. Neurotoxin 2 1jza Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.7 68 ± 15 -5.6
3.2.05.02. Caulonodin 2mlj Caulobacter sp. Secreted 1 0 2.4 ± 1.7 87 ± 15 -5.0
2.2.27.01. Beta-chimaerin 1xa6 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 1.7 65 ± 7 -5.1
3.1.20.01. Alpha-conotoxin GIA 1not Conus geographus (Geography cone) Secreted 1 0 1.6 ± 1.5 89 ± 20 -2.3
1.3.01.03. Outer membrane porin F 4rlc Pseudomonas aeruginosa Bact. Gram-neg outer 1 8 24.2 ± 1.3 14 ± 2 -40.5
1.1.01.02. P2Y purinoceptor 1, conformation 1 4xnv Homo sapiens Eukaryo. plasma 1 7 32.6 ± 1.7 6 ± 1 -70.3
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 1 2gek Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 3.4 ± 2.6 85 ± 5 -5.7
3.1.12.01. Endothelin-1 3cmh Rattus norvegicus Secreted 1 0 6.3 ± 3.9 72 ± 40 -4.8
2.1.24.01. Pore-forming peptide ameobapore A 1of9 Entamoeba histolytica Undefined 1 0 1.5 ± 1.0 13 ± 18 -2.3
1.2.04.01. Integrin alpha-1, 1135-1179 peptide 2l8s Homo sapiens Eukaryo. plasma 1 1 32.0 ± 3.7 40 ± 1 -34.5
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form, mutant 4os0 Homo sapiens Endoplasm. reticulum 1 0 2.4 ± 1.0 77 ± 4 -3.1
2.2.41.02. Sea anemone neurotoxin-1 1shi Stoichactis helianthus Secreted 1 0 8.0 ± 1.0 87 ± 17 -5.9
2.3.06.09. Cutinase 4oyy Humicola insolens (Soft-rot fungus) Secreted 1 0 4.9 ± 1.4 46 ± 6 -10.0
1.2.45.02. Small hydrophobic protein, peptide 1-14 2nb7 Human respiratory syncytial virus Viral 1 0 4.1 ± 0.9 84 ± 6 -7.7
2.3.01.02. Beta-glucosidase 6 3gnr Oryza sativa (Rice) Secreted 1 0 4.8 ± 0.2 80 ± 1 -12.4
1.3.28.01. LPS-assembly protein complex, LptE and LptD 5iva Pseudomonas aeruginosa Bact. Gram-neg outer 1 26 23.2 ± 0.7 4 ± 0 -76.4
2.4.05.02. SDS hydrolase SdsA1 2cfu Pseudomonas aeruginosa Secreted 1 0 6.0 ± 2.5 70 ± 4 -7.0
1.1.25.05. Peptide transporter 6ei3 Xanthomonas campestris Bact. Gram-neg inner 1 14 29.8 ± 0.8 13 ± 1 -98.0
1.2.32.01. Cytochrome P450 2B4, closed state, mutant 5iut Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.3 ± 0.5 56 ± 2 -13.0
2.4.11.01. Crambin 1ejg Crambe abyssinica Secreted 1 0 4.0 ± 1.7 79 ± 15 -7.0
1.1.46.01. MerF bacterial mercury uptake transporter, structure 2 2m67 Morganella morganii Bact. Gram-neg inner 1 2 24.2 ± 4.7 30 ± 1 -29.7
2.1.02.01. Seed lipoxygenase-1 1yge Glycine max Eukaryo. plasma 1 0 3.0 ± 2.6 68 ± 3 -6.4
2.1.21.02. Matrix protein p10 5hyb Mouse mammary tumor virus Viral 1 0 12.9 ± 10.0 73 ± 10 -9.4
2.2.21.05. Kunitz-type proteinase inhibitor BbCI 2gzb Bauhinia bauhinioides Secreted 1 0 7.9 ± 0.3 28 ± 3 -9.3
1.2.03.05. Prolactin receptor (230-264) 2n7i Homo sapiens Eukaryo. plasma 1 1 31.8 ± 4.1 12 ± 8 -21.2
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 4 3spw Saccharomyces cerevisiae Golgi 1 0 7.3 ± 1.1 60 ± 9 -4.5
2.1.42.01. PapB 2ip6 Pediococcus pentosaceus Secreted 1 0 0.6 ± 2.6 72 ± 23 -2.2
3.2.10.01. PawS derived peptide 7 2lwu Designed proteins Undefined 1 0 2.0 ± 1.4 81 ± 10 -3.0
1.3.20.01. Ferric hydroxamate uptake receptor FhuA 1qfg Escherichia coli Bact. Gram-neg outer 1 22 24.7 ± 1.0 5 ± 1 -81.3
1.1.09.01. Calcium ATPase, E1-2Ca state 5mpm Sus scrofa Endoplasm. reticulum 1 10 31.0 ± 0.6 19 ± 0 -76.0
3.2.04.01. Cyclic trypsin inhibitor STFI-1, permutant 1o8y Helianthus annuus Secreted 1 0 3.4 ± 1.3 83 ± 18 -6.0
2.2.41.01. Gallinacin-7 5lcs Gallus gallus Secreted 1 0 2.5 ± 1.4 85 ± 5 -5.6
2.3.18.01. Choline O-acetyltransferase 2fy2 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 2.2 87 ± 17 -5.2
1.3.22.01. VDAC-2 channel 4bum Danio rerio Mitochon. outer 1 19 23.4 ± 0.9 4 ± 0 -47.7
2.4.16.05. Eurocin 2lt8 Eurotium amstelodami Secreted 1 0 5.3 ± 1.3 84 ± 12 -5.5
2.1.18.01. Annexin VI 1m9i Homo sapiens Eukaryo. plasma 1 0 2.8 ± 0.3 82 ± 0 -8.5
1.1.20.03. Claudin-4 5b2g Homo sapiens Eukaryo. plasma 1 4 35.6 ± 2.1 7 ± 2 -45.8
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-bound 1o7k Homo sapiens Endosome 1 0 15.2 ± 1.7 60 ± 15 -18.4
3.1.15.01. Curvacin-A 2a2b Lactobacillus curvatus Secreted 1 0 2.5 ± 1.3 34 ± 18 -6.7
2.2.41.01. Chimeric beta-defensin 2/3 2lxo Designed proteins Undefined 1 0 3.6 ± 0.8 56 ± 14 -5.6
1.3.20.01. Colicin I receptor complex with binding domain of Colicin Ia 2hdi Escherichia coli Bact. Gram-neg outer 1 22 23.4 ± 0.9 3 ± 3 -72.7
2.3.06.06. Lipase 2 1thg Geotrichum candidum Secreted 1 0 6.4 ± 1.7 23 ± 14 -4.7
2.1.42.01. Lactococcin-A immunity protein 5lfi Lactococcus lactis Secreted 1 0 2.7 ± 1.4 40 ± 9 -4.8
2.2.20.01. FYVE, RhoGEF and PH domain-containing protein 6 1wgq Mus musculus Eukaryo. plasma 1 0 2.5 ± 1.8 68 ± 17 -3.2
1.2.39.01. Endoplasmic reticulum aminopeptidase 1, different conformation 2yd0 Homo sapiens Endoplasm. reticulum 1 0 4.1 ± 2.2 59 ± 8 -4.6
2.2.39.01. Cardiotoxin-A5 1kxi Naja atra Secreted 1 0 6.3 ± 1.1 69 ± 15 -10.5
2.4.11.01. Viscotoxin B 1jmp Viscum album Secreted 1 0 1.2 ± 1.4 52 ± 13 -3.2
2.2.36.01. Lactococcin 972 2lgn Lactococcus lactis Secreted 1 0 1.7 ± 2.8 56 ± 9 -3.3
1.2.03.02. Hepatitis A virus cellular receptor 2 homolog 3kaa Mus musculus Eukaryo. plasma 1 0 2.8 ± 2.0 55 ± 16 -5.5
1.2.32.01. Cytochrome P450 2B4, open state 1 2bdm Oryctolagus cuniculus Endoplasm. reticulum 1 0 10.6 ± 1.0 48 ± 15 -16.2
2.1.13.01. Molt-inhibiting hormone 1j0t Marsupenaeus japonicus Secreted 1 0 4.1 ± 0.4 66 ± 6 -7.0
1.1.47.01. Sensor protein kdpD 2ksf Escherichia coli Bact. Gram-neg inner 1 4 26.2 ± 4.0 45 ± 1 -27.9
1.1.107.01. Scavenger receptor B-1 5ktf Mus musculus Eukaryo. plasma 1 1 30.0 ± 2.8 41 ± 1 -25.1
3.1.07.01. Fusion peptide of spike glycoprotein (772-787) 2rum Human SARS coronavirus Endosome 1 0 11.1 ± 1.1 57 ± 13 -10.8
2.2.33.01. Antimicrobial peptide 1b 2lb7 Triticum kiharae (Wheat) Secreted 1 0 2.2 ± 0.7 89 ± 7 -2.5
2.2.11.01. Extended synaptotagmin-2, SMP-C2A-C2B domains 4p42 Homo sapiens Eukaryo. plasma 1 0 5.5 ± 2.8 67 ± 6 -3.3
1.2.38.01. Glycosyltransferase MtgA 3hzs Staphylococcus aureus Bact. Gram-pos plas. 1 0 7.0 ± 1.1 54 ± 9 -14.6
3.1.15.02. Plantaricin-A 1ytr Lactobacillus plantarum Secreted 1 0 9.0 ± 0.5 78 ± 10 -9.4
2.1.01.01. Basic phospholipase A2 myotoxin III 5tfv Bothrops asper Secreted 1 0 6.1 ± 2.0 76 ± 5 -10.4
2.1.02.01. 9R-lipoxygenase 5ek8 Synechococcus sp. Bact. Gram-neg inner 1 0 4.0 ± 0.7 78 ± 6 -12.2
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase SMURF1 3pyc Homo sapiens Eukaryo. plasma 1 0 4.5 ± 2.1 23 ± 17 -5.7
1.2.32.01. Cytochrome P450 2B6, conformation 1 3ibd Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 1.0 57 ± 3 -10.8
2.1.01.01. Phospholipase A2, group IB 1g4i Bos taurus Secreted 1 0 1.9 ± 0.5 87 ± 4 -7.4
3.4.01.01. Contryphan-Lo 2m6h Conus loroisii Secreted 1 0 3.3 ± 0.8 89 ± 14 -5.4
2.4.06.01. Cholesterol-regulated Start protein 4 (StarD4) 5brl Mus musculus Eukaryo. plasma 1 0 3.7 ± 1.1 67 ± 13 -3.7
3.1.31.01. Dermcidin, structure 1 2ksg Homo sapiens Secreted 1 0 4.7 ± 1.4 45 ± 6 -7.0
1.3.04.03. Lipid A acylase PagP, different conformation of loops 1thq Escherichia coli Bact. Gram-neg outer 1 8 23.4 ± 2.5 27 ± 3 -31.3
1.2.18.01. Sortase B 1rz2 Bacillus anthracis Bact. Gram-pos plas. 1 0 3.0 ± 0.6 82 ± 6 -5.8
2.1.29.01. Apolipoprotein E 1ya9 Mus musculus Secreted 1 0 1.6 ± 1.4 85 ± 11 -4.1
2.3.06.04. Palmitoyl protein thioesterase 2 1pja Homo sapiens Lysosome 1 0 3.7 ± 1.6 60 ± 15 -4.6
1.1.56.01. Inner membrane protein YejM, strain LT2 5i5f Salmonella typhimurium Bact. Gram-neg inner 1 0 3.7 ± 2.4 62 ± 11 -4.9
2.2.34.11. Cycloviolacin O1 1df6 Viola odorata Secreted 1 0 4.1 ± 1.2 63 ± 19 -5.9
2.1.60.03. Natrin-1 1xx5 Naja atra Secreted 1 0 2.6 ± 2.4 60 ± 49 -5.2
2.3.16.09. GTP-binding protein YjiA 1nij Escherichia coli Bact. Gram-neg inner 1 0 3.4 ± 0.1 41 ± 1 -6.7
2.1.15.03. Clathrin assembly lymphoid myeloid leukemia (CALM) protein 1hfa Rattus norvegicus Eukaryo. plasma 1 0 14.2 ± 2.0 44 ± 14 -17.9
2.2.19.01. Adsorption protein p2 1n7v Bacteriophage prd1 Viral 1 0 8.7 ± 0.4 81 ± 1 -8.6
2.2.34.02. U1-theraphotoxin-Hh1a 1i25 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.6 ± 0.2 79 ± 1 -5.1
1.3.20.01. Ferric hydroxamate uptake receptor FhuA, with microcin 4cu4 Escherichia coli Bact. Gram-neg outer 1 22 24.6 ± 1.1 5 ± 0 -77.7
1.1.01.01. Proteorhodopsin 4hyj Exiguobacterium sibiricum Bact. Gram-pos plas. 1 7 30.0 ± 1.6 15 ± 7 -56.8
2.3.06.09. Cutinase-like protein 2czq Cryptococcus sp. Secreted 1 0 4.9 ± 1.3 54 ± 16 -9.0
2.2.58.01. Cone arrestin 1suj Ambystoma tigrinum (Tiger salamander) Eukaryo. plasma 1 0 1.4 ± 0.8 82 ± 12 -4.7
2.4.13.01. Oxysterol-binding protein homolog 3 4ic4 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 4.3 ± 0.9 86 ± 29 -5.9
2.4.16.04. Defensin-like protein 1 1ayj Raphanus sativus Secreted 1 0 11.0 ± 1.9 39 ± 19 -7.4
2.4.16.02. Coprisin 2ln4 Copris tripartitus Secreted 1 0 4.5 ± 0.6 42 ± 4 -5.3
1.1.25.06. D-xylose-proton symporter xylE, conformation 1 4gc0 Escherichia coli Bact. Gram-neg inner 1 12 30.2 ± 0.9 1 ± 0 -90.2
2.2.20.01. Spectrin beta chain 1btn Mus musculus Eukaryo. plasma 1 0 13.7 ± 1.6 57 ± 19 -17.3
1.1.01.02. D2 dopamine receptor 6c38 Homo sapiens Eukaryo. plasma 1 7 31.8 ± 2.2 9 ± 1 -68.4
2.1.21.02. Matrix protein p10 2f76 Mason-Pfizer monkey virus Viral 1 0 3.9 ± 1.2 48 ± 5 -5.8
3.1.11.01. Peptide YY 1ru5 Sus scrofa Secreted 1 0 5.1 ± 1.2 83 ± 3 -5.3
2.1.01.01. Phospholipase A2 homolog 1ppa Agkistridon piscivorus Secreted 1 0 1.2 ± 0.9 85 ± 8 -4.5
2.1.48.01. Glycerol dehydrogenase 1kq3 Thermotoga maritima Undefined 1 0 2.5 ± 1.8 80 ± 5 -4.3
2.3.06.03. Gastric lipase, open (active) state 1k8q Canis lupus familiaris Secreted 1 0 7.2 ± 0.5 78 ± 6 -12.6
2.3.06.17. Phosphatidylcholine-sterol acyltransferase, structure 2 4xwg Homo sapiens Secreted 1 0 3.7 ± 0.7 37 ± 4 -6.1
2.2.04.01. Retinoid isomerohydrolase, conformation 1 3fsn Bos taurus Eukaryo. plasma 1 0 7.8 ± 1.0 73 ± 10 -10.3
1.2.43.01. Envelope glycoprotein, West Nile virus, structure 4 3iyw West Nile virus Viral 1 0 6.6 ± 2.9 30 ± 15 -4.5
2.1.02.01. Manganese lipoxygenase 5fno Magnaporthe oryzae Eukaryo. plasma 1 0 4.7 ± 0.7 61 ± 2 -9.7
2.4.06.01. START domain of collagen type IV alpha-3-binding protein 2e3q Homo sapiens Golgi 1 0 4.3 ± 2.0 41 ± 17 -3.7
2.4.11.01. Viscotoxin A1 3c8p Viscum album Secreted 1 0 2.3 ± 0.9 45 ± 7 -4.9
2.3.27.01. Dihydrofolate reductase 3nzb Pneumocystis carinii Undefined 1 0 3.9 ± 1.9 72 ± 10 -5.9
3.1.02.01. Apelin receptor, peptide 1-55 2low Homo sapiens Eukaryo. plasma 1 1 26.4 ± 5.1 35 ± 2 -16.7
1.2.32.01. Cytochrome P450 4B1 5t6q Oryctolagus cuniculus Endoplasm. reticulum 1 0 8.8 ± 0.6 38 ± 2 -17.0
3.1.11.01. Neuropeptide Y-pancreatic polypeptide hybrid 1tz4 Sus scrofa Secreted 1 0 5.1 ± 1.0 88 ± 8 -6.1
2.2.11.01. Extended synaptotagmin-2, third C2 domain 2dmg Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.0 76 ± 5 -4.8
2.2.56.01. Beta-2-glycoprotein 1 3op8 Homo sapiens Secreted 1 0 4.2 ± 1.8 47 ± 10 -6.1
1.1.63.01. Type 1 signal peptidase, apo-enzyme 1kn9 Escherichia coli Bact. Gram-neg inner 1 0 3.4 ± 1.4 80 ± 6 -7.8
2.1.15.01. Epsin-1 1h0a Rattus norvegicus Eukaryo. plasma 1 0 3.2 ± 1.1 39 ± 19 -5.3
1.1.117.01. DHHC20 palmitoyltransferase, structure 2 6bmm Homo sapiens Golgi 1 4 30.2 ± 4.4 20 ± 2 -50.0
2.2.34.05. Tachystatin-A2 1cix Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 3.9 ± 2.9 65 ± 14 -4.7
3.1.05.13. Cullin3-derived peptides 2myl Designed proteins Undefined 1 0 3.4 ± 1.2 82 ± 21 -4.4
1.3.20.01. Fe(III)-pyochelin receptor FptA 1xkw Pseudomonas aeruginosa Bact. Gram-neg outer 1 22 24.8 ± 1.0 5 ± 4 -84.3
3.4.02.02. Mersacidin, structure in DPC micelles 1mqy Bacillus sp. Secreted 1 0 5.3 ± 0.9 90 ± 12 -6.1
1.2.39.02. Matrilysin, structure 2 2mzi Homo sapiens Secreted 1 0 3.5 ± 0.5 71 ± 4 -7.7
3.1.28.04. Temporin-A 2maa Rana temporaria Secreted 1 0 7.2 ± 0.5 66 ± 7 -8.4
2.1.20.01. Prothrombin 1nl2 Bos taurus Eukaryo. plasma 1 0 3.9 ± 3.0 18 ± 24 -5.8
2.4.07.01. Sorting nexin-5 3hpc Rattus norvegicus Endosome 1 0 0.0 ± 2.1 90 ± 8 -2.4
2.2.28.01. Tachycitin 1dqc Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 4.5 ± 0.8 78 ± 8 -5.6
2.1.10.01. Ceramide-1-phosphate transfer protein 4k8n Homo sapiens Eukaryo. plasma 1 0 7.0 ± 1.0 81 ± 4 -10.6
3.1.25.01. Latarcin-2a (M-zodatoxin-Lt2a) 2g9p Lachesana tarabaevi (Spider) Secreted 1 0 8.5 ± 1.4 77 ± 9 -6.4
1.3.20.01. Outer membrane cobalamin transporter BtuB, complex with colicin E3 R-domain 1ujw Escherichia coli Bact. Gram-neg outer 1 22 23.6 ± 1.1 5 ± 0 -71.5
2.2.20.01. PH domain of GPCR kinase 1 1bak Homo sapiens Eukaryo. plasma 1 0 3.6 ± 0.9 88 ± 2 -6.0
2.4.04.01. Sphingomyelinase C 2ddt Bacillus cereus Secreted 1 0 4.1 ± 1.1 59 ± 8 -7.6
2.2.39.01. Ancestral Mamba toxin 1 5mg9 Dendroaspis angusticeps (Eastern green mamba) Secreted 1 0 4.2 ± 1.2 49 ± 6 -8.0
1.1.25.07. Nitrate/nitrite exchanger NarK, inward-open state 4u4t Escherichia coli Bact. Gram-neg inner 1 12 31.2 ± 1.1 5 ± 1 -94.2
3.1.02.05. Acetylcholine receptor, subunit beta2, TMH 1 2k58 Homo sapiens Eukaryo. plasma 1 1 30.6 ± 6.0 39 ± 7 -22.0
1.2.32.01. Prostacyclin synthase (cytochrome P450 8A1) 3b6h Homo sapiens Endoplasm. reticulum 1 0 5.0 ± 1.6 64 ± 18 -6.3
2.1.01.01. Snake phospholipase A2, group II 1pp2 Crotalus atrox Secreted 1 0 3.7 ± 1.3 80 ± 7 -12.9
2.4.42.01. Bactericidal permeability-increasing protein 1bp1 Homo sapiens Secreted 1 0 1.5 ± 2.4 51 ± 17 -4.3
1.1.25.04. L-fucose-proton symporter fucP 3o7q Escherichia coli Bact. Gram-neg inner 1 12 30.7 ± 1.3 6 ± 0 -85.3
2.2.06.02. Cellular retinoic acid-binding protein 1 1cbr Bos taurus Eukaryo. plasma 1 0 6.5 ± 1.1 45 ± 11 -5.4
1.2.51.01. Alkaline sphingomyelinase 5udy Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.3 84 ± 10 -4.5
2.2.26.01. FYVE domain of Vps27 protein 1vfy Saccharomyces cerevisiae Vacuole 1 0 3.7 ± 1.8 24 ± 19 -4.2
3.1.30.01. Lactoferrin-based peptide, 39-49 2gmc Homo sapiens Secreted 1 0 3.9 ± 1.7 79 ± 13 -4.6
1.1.01.01. Bacteriorhodopsin, monomer 1py6 Halobacterium salinarum Archaebac. 1 7 29.6 ± 2.2 24 ± 8 -59.7
1.2.27.01. Fst toxin 2kv5 Enterococcus faecalis Bact. Gram-pos plas. 1 1 26.0 ± 2.9 35 ± 8 -18.9
2.2.34.02. Jingzhaotoxin-11 2a2v Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.0 ± 1.8 74 ± 19 -4.6
2.3.06.09. Rv3802 phospholipase 5w95 Mycobacterium tuberculosis Secreted 1 0 5.0 ± 1.6 14 ± 5 -6.9
1.1.77.01. Cellulose synthase, structure 4 5ejz Rhodobacter sphaeroides Bact. Gram-neg inner 1 8 29.6 ± 1.1 18 ± 0 -86.9
2.1.17.01. Small hydrophilic endoplasmic reticulum-associated protein (Sherp) 2x43 Leishmania major Endoplasm. reticulum 1 0 4.1 ± 0.3 82 ± 2 -9.0
2.2.06.01. Complement component C8 gamma chain 1lf7 Homo sapiens Secreted 1 0 1.9 ± 2.2 43 ± 12 -2.6
3.4.12.02. Thiostrepton 1e9w Streptomyces azureus Secreted 1 0 7.3 ± 1.5 86 ± 15 -4.9
1.1.02.05. Light-harvesting protein B-875, beta chain 1jo5 Rhodobacter sphaeroides Bact. Gram-neg inner 1 1 29.6 ± 1.5 20 ± 2 -24.7
2.2.12.02. Rho GDP-dissociation inhibitor 1 1qvy Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.7 53 ± 19 -5.1
2.3.08.02. Cytosolic phospholipase A2 delta, structure 1 5ixc Homo sapiens Vesicle 1 0 5.5 ± 2.0 85 ± 31 -4.4
2.2.34.08. Agouti-signaling protein 1y7j Homo sapiens Secreted 1 0 3.8 ± 1.6 62 ± 7 -6.9
1.1.64.01. Sodium/calcium exchanger, structure 1 3v5u Methanococcus jannaschii Archaebac. 1 10 29.8 ± 0.9 3 ± 0 -78.4
1.3.19.01. Outer membrane porin OprD, different conformation of loops 3sy7 Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.8 ± 1.1 4 ± 2 -63.5
1.1.07.01. Nitric oxide reductase 3ayf Bacillus stearothermophilus Bact. Gram-pos plas. 1 14 31.6 ± 0.8 8 ± 0 -109.3
2.1.01.01. Snake phospholipase A2, ammodytoxin A, group II 3g8g Vipera ammodytes ammodytes Secreted 1 0 4.1 ± 0.9 80 ± 6 -11.0
1.1.09.01. Calcium ATPase, E2 state (Ca-free), conformation 6 2zbe Oryctolagus cuniculus Endoplasm. reticulum 1 10 28.0 ± 0.7 16 ± 0 -55.4
2.2.34.02. ACTX-HI:OB4219 1kqi Hadronyche infensa Secreted 1 0 5.2 ± 1.2 72 ± 15 -8.2
3.1.28.02. Neuromedin-B 1c98 Homo sapiens Secreted 1 0 4.3 ± 1.8 77 ± 11 -3.8
2.2.20.01. Son of sevenless homolog 1 (SOS-1) 1xd4 Homo sapiens Eukaryo. plasma 1 0 1.9 ± 3.0 79 ± 2 -4.5
3.1.07.04. Envelope glycoprotein E1, heterodimerization peptide (350-370) 1emz Hepatitis C virus Viral 1 0 6.2 ± 0.2 86 ± 9 -8.5
3.2.02.02. Chi-conotoxin MrIB 1ieo Conus marmoreus Secreted 1 0 2.2 ± 1.1 45 ± 12 -1.9
1.1.39.04. Nickel/cobalt transporter CbiM 4m58 Thermoanaerobacter tengcongensis Bact. Gram-pos plas. 1 7 29.8 ± 0.9 18 ± 2 -59.8
3.1.18.01. Delta-hemolysin 1dtc Staphylococcus aureus Secreted 1 0 3.2 ± 2.2 87 ± 19 -8.5
3.4.07.01. Antimicrobial cationic cyclic hexapeptide 1qvl Designed proteins Undefined 1 0 4.2 ± 1.6 84 ± 15 -6.8
2.1.02.01. Arachidonate 15-lipoxygenase 5med Synechococcus sp. Bact. Gram-neg inner 1 0 3.3 ± 1.6 75 ± 7 -7.4
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 1 2w61 Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.4 ± 2.3 60 ± 7 -5.4
2.2.39.01. Toxin B 1txa Ophiophagus hannah Secreted 1 0 2.6 ± 1.5 51 ± 16 -5.6
2.2.32.01. ADP-ribosylating toxin CARDS, full-length 4tlw Mycoplasma pneumoniae Secreted 1 0 1.5 ± 1.4 47 ± 2 -4.8
1.1.01.02. Adenosine receptor A2a, inactive state, complex with antagonist 3eml Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 8 ± 12 -66.1
1.2.54.01. Dihydroorotate dehydrogenase 1d3h Homo sapiens Mitochon. inner 1 0 3.4 ± 0.8 55 ± 6 -10.1
1.2.43.01. Envelope glycoprotein, West Nile virus, structure 1 2hg0 West Nile virus Viral 1 0 4.8 ± 2.6 44 ± 4 -4.3
3.2.06.01. Growth-blocking peptide, long form 2eqt Pseudaletia separata (Oriental armyworm) Secreted 1 0 4.1 ± 1.4 59 ± 8 -5.7
1.3.19.01. Porin OccAB4 5dl8 Acinetobacter baumannii Bact. Gram-neg outer 1 18 21.4 ± 2.3 3 ± 0 -60.7
1.1.01.02. Opioid mu receptor, active state 5c1m Mus musculus Eukaryo. plasma 1 7 34.4 ± 2.9 9 ± 0 -83.2
2.2.12.01. Lymphocyte antigen 96, structure 1 2e56 Homo sapiens Secreted 1 0 3.6 ± 0.7 68 ± 4 -6.7
2.3.22.01. Uncharacterized protein 1rtt Pseudomonas aeruginosa Undefined 1 0 3.1 ± 2.5 70 ± 22 -4.1
2.3.06.07. Lipase 1qge Pseudomonas glumae Secreted 1 0 3.7 ± 0.9 24 ± 3 -7.7
2.3.19.01. Toxin A 4r04 Clostridium difficile Secreted 1 0 3.2 ± 2.4 74 ± 2 -6.7
1.1.25.07. Nitrite exporter NarU 4iu9 Escherichia coli Bact. Gram-neg inner 1 12 31.0 ± 1.2 4 ± 0 -88.1
3.1.02.05. Glycine receptor, alpha-1 subunit, TMH 2+3 1vry Homo sapiens Eukaryo. plasma 1 2 23.2 ± 3.7 5 ± 9 -25.3
2.3.13.04. Phospholipid hydroperoxide glutathione peroxidase 5l71 Mus musculus Mitochon. inner 1 0 7.1 ± 1.8 83 ± 14 -5.1
2.2.45.02. Pectate lyase A 1pe9 Erwinia chrysanthemi Secreted 1 0 2.7 ± 0.4 81 ± 3 -6.4
2.2.05.01. Amicyanin 1id2 Paracoccus versutus Bact. Gram-neg inner 1 0 4.2 ± 1.3 52 ± 8 -4.9
2.3.19.02. Histo-blood group ABO system transferase 2rj6 Homo sapiens Golgi 1 0 2.1 ± 1.3 77 ± 3 -7.1
2.4.16.01. Alpha-like toxin CsEv5 1i6f Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.4 ± 1.3 59 ± 4 -5.8
3.1.05.03. LAK160-P10 2l99 Designed proteins Undefined 1 0 3.9 ± 2.6 84 ± 0 -5.0
1.3.13.01. Bacterial Nucleoside Transporter Ts 1tly Escherichia coli Bact. Gram-neg outer 1 12 23.4 ± 1.5 8 ± 0 -48.1
1.1.113.01. ERAD-associated E3 ubiquitin-protein ligase component HRD3 5v7v Saccharomyces cerevisiae Endoplasm. reticulum 1 0 8.3 ± 2.6 75 ± 3 -18.6
3.1.19.01. Cephaibol B 1ob6 Acremonium tubakii Secreted 1 0 15.0 ± 5.0 42 ± 17 -15.3
2.2.34.02. Protoxin-II 5o0u Thrixopelma pruriens Secreted 1 0 4.8 ± 3.8 60 ± 2 -8.5
1.1.09.01. Copper efflux ATPase, E2P state 4bbj Legionella pneumophila Bact. Gram-neg inner 1 8 30.2 ± 0.9 16 ± 1 -69.4
1.2.61.01. Mitochondrial inner membrane translocase subunit TIM50 4qqf Saccharomyces cerevisiae Mitochon. inner 1 0 5.4 ± 0.8 76 ± 1 -7.0
2.2.01.01. F18 fimbrial adhesin AC, FedF 4b4q Escherichia coli Secreted 1 0 1.8 ± 2.6 81 ± 20 -3.4
1.1.44.01. DsbB - DsbA complex, conformation 1 2hi7 Escherichia coli Bact. Gram-neg inner 1 4 24.3 ± 3.0 30 ± 0 -34.9
3.1.29.01. Cathelicidin-3, peptide 121-151 2hfr Gallus gallus Secreted 1 0 3.1 ± 4.2 86 ± 1 -8.0
3.2.01.09. Transthyretin-derived peptide 5hpp Designed proteins Undefined 1 0 2.7 ± 1.6 83 ± 6 -5.2
1.3.05.01. Lipid A deacylase PagL 2erv Pseudomonas aeruginosa Bact. Gram-neg outer 1 8 24.7 ± 1.8 20 ± 2 -41.1
2.1.01.01. Snake phospholipase A2 isoform 5, group I 1y75 Naja sagittifera Secreted 1 0 4.4 ± 0.7 81 ± 10 -5.7
2.2.34.02. Spiderine-1a, 108-165 2n86 Oxyopes takobius (Lynx spider) Secreted 1 0 5.8 ± 3.7 57 ± 6 -5.7
2.3.10.07. Lipopolysaccharide biosynthesis protein RfaG 2iw1 Escherichia coli Bact. Gram-neg inner 1 0 3.7 ± 3.1 85 ± 8 -6.0
1.1.01.02. Adenosine receptor A2a, partially active state, engineered, complex with agonist 2ydv Homo sapiens Eukaryo. plasma 1 7 31.0 ± 1.3 10 ± 0 -61.4
1.2.32.01. Cytochrome P450 2C9, structure 1 1og5 Homo sapiens Endoplasm. reticulum 1 0 7.6 ± 1.0 79 ± 6 -13.7
2.1.60.02. Lasiocepsin 2mbd Lasioglossum laticeps Secreted 1 0 0.6 ± 1.3 47 ± 15 -2.5
2.2.14.01. C2 domain of coagulation factor VIII 1d7p Homo sapiens Eukaryo. plasma 1 0 4.8 ± 2.0 28 ± 10 -8.8
3.1.07.02. Juxtamembrane peptide (684-719) of protein gp41 2kzq Hepatitis C virus Endosome 1 0 4.3 ± 3.3 88 ± 0 -9.9
3.1.28.06. Magainin 2 2mag Xenopus laevis Secreted 1 0 10.1 ± 0.9 81 ± 14 -13.7
2.4.16.04. Flower-specific defensin D1, monomer 4ab0 Nicotiana alata (Winged tobacco) Secreted 1 0 3.5 ± 1.2 55 ± 13 -4.3
2.4.04.01. Inositol polyphosphate 5-phosphatase OCRL-1 4cmn Homo sapiens Endosome 1 0 6.7 ± 1.6 83 ± 2 -9.2
3.1.10.01. Competence-stimulating peptide type 1 2a1c Streptococcus pneumoniae Secreted 1 0 4.8 ± 0.9 85 ± 20 -7.7
1.3.11.01. Autotransporter BrkA 3qq2 Bordetella pertussis Bact. Gram-neg outer 1 12 24.6 ± 1.5 4 ± 1 -44.1
1.2.01.01. Insulin receptor, peptide 938-988 2mfr Homo sapiens Eukaryo. plasma 1 1 29.8 ± 4.8 41 ± 1 -29.2
2.3.06.06. Lipase LipA 2qua Serratia marcescens Secreted 1 0 8.9 ± 0.2 59 ± 0 -37.5
3.2.01.01. Arenicin-3 5y0i Arenicola marina Secreted 1 0 3.0 ± 1.6 83 ± 5 -3.9
1.1.26.07. STAS domain of sulfate permease 4dgh Vibrio cholerae Bact. Gram-neg inner 1 0 4.6 ± 0.6 33 ± 2 -6.2
3.1.04.03. Viral protein R, peptide 13-33, different strain 1fi0 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 2.7 ± 1.2 88 ± 8 -8.6
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3l4d Leishmania infantum Endoplasm. reticulum 1 0 8.4 ± 1.8 66 ± 9 -12.6
2.1.01.01. Snake phospholipase A2, group I, KPA2 1g2x Bungarus caeruleus Secreted 1 0 3.8 ± 1.5 84 ± 10 -5.4
2.2.34.02. Mu-cyrtautoxin-As1a 2m36 Apomastus schlingeri Secreted 1 0 1.7 ± 1.0 49 ± 35 -3.2
1.1.02.05. Light-harvesting complex LH1, alpha chain 1xrd Rhodospirillum rubrum Bact. Gram-neg inner 1 1 30.3 ± 3.1 30 ± 4 -30.5
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 405-424 1btq Homo sapiens Eukaryo. plasma 1 0 13.6 ± 2.1 67 ± 11 -22.5
1.1.01.02. Proteinase-activated receptor 2 5ndd Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.4 11 ± 2 -71.1
2.2.03.01. Saccharopepsin 1fq5 Saccharomyces cerevisiae Vacuole 1 0 3.8 ± 0.8 84 ± 6 -8.1
2.2.34.02. Omega-theraphotoxin-Gr1a 1koz Grammostola rosea (Chilean rose tarantula) Secreted 1 0 3.6 ± 0.8 68 ± 6 -6.5
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2 2w8d Bacillus subtilis Bact. Gram-pos plas. 1 0 0.0 ± 6.0 83 ± 58 -1.6
3.1.29.03. Tritrpticin 1d6x Sus scrofa Secreted 1 0 9.4 ± 2.6 81 ± 38 -8.1
1.1.26.01. Leucine transporter LeuT, outward-facing, return state, mutant 5jag Aquifex aeolicus Bact. Gram-neg inner 1 12 26.8 ± 1.1 11 ± 0 -80.7
3.1.04.03. Viral protein R, peptide 34-51 1kzt Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.4 ± 0.6 77 ± 7 -10.3
2.3.16.08. Interferon-inducible GTPase 1 1tpz Mus musculus Endoplasm. reticulum 1 0 2.5 ± 2.0 37 ± 7 -5.0
2.2.06.01. Retinol binding protein 1aqb Sus scrofa Secreted 1 0 4.1 ± 1.1 75 ± 14 -4.4
2.1.25.03. Enterocin 7B 2m60 Enterococcus faecalis Secreted 1 0 3.2 ± 1.6 53 ± 15 -3.8
1.2.32.01. Cytochrome P450 1n97 Thermus thermophilus Bact. Gram-neg inner 1 0 5.2 ± 0.3 43 ± 5 -9.9
2.2.20.01. PH domain of TAPP2 1v5p Mus musculus Eukaryo. plasma 1 0 1.4 ± 1.3 61 ± 5 -3.7
3.1.03.07. N-terminal peptide (24-58) of Disabled homolog 2 2lsw Homo sapiens Vesicle 1 0 2.1 ± 0.6 85 ± 5 -3.8
2.2.34.01. Conotoxin Gm9 1ixt Conus gloriamaris (Glory-of-the-Seas cone) Secreted 1 0 1.7 ± 1.7 85 ± 17 -3.0
1.3.19.01. Porin OpdR 4fsp Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 22.6 ± 1.2 3 ± 0 -59.6
2.2.07.01. Lipocalin BcnB 5ixg Burkholderia cepacia Bact. Gram-neg inner 1 0 2.0 ± 1.0 36 ± 5 -3.9
1.2.32.01. Cytochrome P450 2B4, closed state 3 3g5n Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.7 ± 1.8 65 ± 3 -12.1
2.4.16.01. Beta-mammal toxin Cn2 2yc1 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.8 ± 1.1 68 ± 9 -3.8
1.2.50.01. Fragaceatoxin C, complex with lipids 4tsq Actinia fragacea (Strawberry anemone) Secreted 1 0 2.2 ± 0.9 38 ± 3 -15.5
2.2.27.01. C1 domain of unc-13 homolog A 1y8f Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 1.9 16 ± 17 -2.9
3.1.20.01. Alpha-conotoxin GID 1mtq Conus geographus (Geography cone) Secreted 1 0 1.3 ± 2.5 78 ± 28 -2.4
1.3.06.02. Carbapenem-associated resistance porin CarO1 4rl9 Acinetobacter baumannii Bact. Gram-neg outer 1 8 24.6 ± 1.5 3 ± 1 -38.3
1.1.01.02. P2Y purinoceptor 1, conformation 2 4xnw Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.3 5 ± 1 -72.0
1.1.26.01. MhsT transporter, inward-facing state 4us3 Bacillus halodurans Bact. Gram-pos plas. 1 11 29.8 ± 0.8 11 ± 1 -87.1
3.2.01.02. Thanatin 8tfv Podisus maculiventris Secreted 1 0 3.7 ± 1.0 81 ± 4 -5.3
3.1.07.03. Antimicrobial peptide derived from hemagglutinin 2l24 Influenza virus Undefined 1 0 8.7 ± 1.3 75 ± 10 -12.6
1.1.01.02. Beta-2 adrenergic receptor, inactive state 4gbr Homo sapiens Eukaryo. plasma 1 7 31.6 ± 1.3 7 ± 1 -71.7
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 8 4c0c Trypanosoma cruzi Endoplasm. reticulum 1 0 9.4 ± 1.9 64 ± 7 -10.9
2.2.41.02. Sea anemone toxin IA 1atx Anemonia sulcata Secreted 1 0 4.5 ± 1.7 63 ± 12 -6.1
2.3.06.16. Lipase lip1 4opm Acinetobacter baumannii Secreted 1 0 1.8 ± 1.0 41 ± 3 -4.4
1.2.33.02. Protoporphyrinogen oxidase 1sez Nicotiana tabacum Mitochon. inner 1 0 2.2 ± 1.0 50 ± 3 -7.0
2.3.01.03. Alpha-amylase A 1wza Halothermothrix orenii Secreted 1 0 1.6 ± 0.4 80 ± 1 -6.7
1.3.28.01. LPS-assembly protein complex, LptE and LptD 5ixm Yersinia pestis Bact. Gram-neg outer 1 26 22.8 ± 0.9 6 ± 1 -81.9
1.2.50.01. Fragaceatoxin C, monomer 3lim Actinia fragacea (Strawberry anemone) Secreted 1 0 2.6 ± 0.8 46 ± 15 -5.0
2.3.13.04. Glutathione peroxidase-like protein 2vup Trypanosoma brucei Undefined 1 0 3.0 ± 1.7 84 ± 7 -4.1
3.1.07.07. Fusion protein p14, FAST 2lx0 Reptilian orthoreovirus Eukaryo. plasma 1 1 27.4 ± 2.3 17 ± 9 -20.2
2.4.11.01. beta-Purothionin 1bhp Triticum aestivum Secreted 1 0 2.9 ± 2.0 56 ± 19 -4.8
2.3.06.12. Lipase/esterase 3bjr Lactobacillus plantarum Secreted 1 0 2.1 ± 0.2 72 ± 5 -7.0
1.1.25.05. Bacterial proton:oligopeptide symporter, structure 1 4lep Shewanella oneidensis Bact. Gram-neg inner 1 14 29.4 ± 0.6 7 ± 0 -89.1
2.1.02.01. Seed lipoxygenase-3 1rrh Glycine max Eukaryo. plasma 1 0 3.8 ± 1.3 84 ± 7 -5.6
2.4.21.02. L-alanyl-D-glutamate peptidase 2vo9 Listeria phage A500 Secreted 1 0 3.1 ± 1.0 48 ± 4 -5.2
1.2.25.02. Na,K-ATPase regulatory protein FXYD1 (phospholemman) 2jo1 Homo sapiens Eukaryo. plasma 1 1 30.6 ± 2.5 11 ± 4 -27.8
2.1.41.01. Phosphatidylinositol 4-kinase type 2-alpha, structure 2 4pla Homo sapiens Golgi 1 0 1.0 ± 1.7 49 ± 3 -2.8
2.2.41.01. Defensin-like peptide 2/4 1d6b Ornithorhynchus anatinus Secreted 1 0 9.2 ± 0.7 73 ± 2 -11.0
3.1.05.03. LAK160-P7 2l96 Designed proteins Undefined 1 0 1.4 ± 0.9 88 ± 5 -2.7
1.3.20.01. Ferric enterobactin receptor FepA 1fep Escherichia coli Bact. Gram-neg outer 1 22 24.3 ± 1.1 1 ± 0 -77.2
1.1.10.04. P-glycoprotein, inward-facing conformation 1b 4lsg Mus musculus Eukaryo. plasma 1 12 31.0 ± 8.0 2 ± 0 -85.3
1.1.53.01. RAS methyltransferase ICMT 5v7p Tribolium castaneum Endoplasm. reticulum 1 8 29.8 ± 1.2 14 ± 0 -72.4
3.2.05.02. Microcin J25, peptide 38-58, cleaved after 47 1s7p Escherichia coli Secreted 1 0 4.7 ± 1.2 83 ± 18 -5.7
1.2.42.01. Sphingomyelin phosphodiesterase 5i85 Homo sapiens Secreted 1 0 7.1 ± 1.4 53 ± 2 -9.2
2.3.18.01. Choline O-acetyltransferase 1q6x Rattus norvegicus Eukaryo. plasma 1 0 3.6 ± 0.6 75 ± 6 -8.5
1.2.54.01. Dihydroorotate dehydrogenase, 32-65 peptide 5tce Homo sapiens Mitochon. inner 1 0 3.7 ± 1.2 84 ± 7 -7.4
1.1.83.01. Mitochondrial translocator protein, TSPO, model 1 2mgy Mus musculus Mitochon. outer 1 5 28.6 ± 1.6 12 ± 1 -17.9
2.1.01.01. Basic phospholipase A2 homolog 1 3t0r Bothrops moojeni Secreted 1 0 3.7 ± 1.6 86 ± 12 -2.6
1.1.25.02. Lactose permease LacY, structure 5 4oaa Escherichia coli Bact. Gram-neg inner 1 12 32.6 ± 1.6 2 ± 2 -101.7
2.1.18.01. Annexin VIII 1w3w Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.0 79 ± 9 -6.2
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens Endosome 1 0 2.4 ± 1.6 88 ± 12 -4.6
3.1.15.01. Carnobacteriocin B2 1cw5 Carnobacterium maltaromaticum Secreted 1 0 6.5 ± 0.3 89 ± 5 -9.9
3.2.11.01. Peptide NC_cEE_D1 5kx2 Designed proteins Undefined 1 0 4.9 ± 1.9 70 ± 14 -4.6
1.3.20.01. Colicin I receptor 2hdf Escherichia coli Bact. Gram-neg outer 1 22 23.4 ± 0.9 4 ± 0 -70.9
2.1.02.01. Arachidonate 15-lipoxygenase 4nre Homo sapiens Eukaryo. plasma 1 0 4.5 ± 1.5 83 ± 2 -10.6