PDB ID or protein name

All proteins in OPM (3404 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
1.2.38.03. Endo-type membrane-bound lytic murein transglycosylase A 2y8p Escherichia coli Bact. Gram-neg outer 1 0 0.0 ± 3.6 86 ± 15 -2.2
2.4.07.01. Sorting nexin-5 3hpc Rattus norvegicus Endosome 1 0 0.0 ± 2.1 90 ± 8 -2.4
2.2.06.02. Fatty acid-binding protein 2k62 Gallus gallus Eukaryo. plasma 1 0 0.0 ± 2.9 82 ± 13 -2.0
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2 2w8d Bacillus subtilis Bact. Gram-pos plas. 1 0 0.0 ± 6.0 83 ± 58 -1.6
2.2.06.01. Prostaglandin-H2 D-isomerase 2ktd Mus musculus Endoplasm. reticulum 1 0 0.0 ± 1.4 73 ± 14 -2.2
2.1.01.01. Phospholipase A2, group IB 3elo Homo sapiens Secreted 1 0 0.4 ± 1.5 52 ± 16 -3.5
2.4.05.01. Uncharacterized protein 3bkr Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.4 ± 6.2 50 ± 73 -1.2
2.1.11.01. Alpha-actinin-2 1hci Homo sapiens Eukaryo. plasma 2 0 0.4 ± 0.7 90 ± 12 -5.1
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2w5q Staphylococcus aureus Bact. Gram-pos plas. 1 0 0.4 ± 3.6 82 ± 11 -2.5
3.2.01.07. Protegrin-3, dimer 2mz6 Sus scrofa Secreted 2 0 0.4 ± 2.1 89 ± 2 -2.3
1.2.53.01. Squalene synthase, conformation 4 3wek Homo sapiens Endoplasm. reticulum 1 0 0.4 ± 2.5 87 ± 15 -3.2
2.1.08.01. Cytochrome c6 1c6s Thermosynechococcus elongatus Thylakoid 1 0 0.4 ± 1.7 89 ± 16 -1.3
3.2.01.06. Symmetrical θ-defensin, BTD-2 2lye Macaca mulatta Secreted 1 0 0.4 ± 2.9 80 ± 22 -1.5
3.2.01.04. Gomesin 1kfp Acanthoscurria gomesiana (Tarantula spider) Secreted 1 0 0.5 ± 1.0 75 ± 6 -2.7
2.2.20.01. Cytohesin-2 1u27 Mus musculus Eukaryo. plasma 1 0 0.5 ± 2.4 53 ± 9 -2.4
2.2.06.01. Beta-lactoglobulin 3nq9 Bos taurus Secreted 1 0 0.5 ± 0.9 89 ± 4 -2.7
2.2.20.01. Pleckstrin homology domain-containing family B member 2 2dhi Mus musculus Eukaryo. plasma 1 0 0.6 ± 1.5 86 ± 14 -2.8
2.2.34.02. Hybrid atracotoxin 2h1z Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 0.6 ± 2.0 82 ± 20 -1.9
2.2.06.02. Fatty acid-binding protein 2 2ftb Ambystoma mexicanum (Axolotl) Eukaryo. plasma 1 0 0.6 ± 2.0 77 ± 20 -1.7
1.2.04.01. Integrin beta-3, 742-788, 747pY, in water 2ljf Homo sapiens Eukaryo. plasma 1 0 0.6 ± 1.6 62 ± 14 -1.8
2.1.42.01. PapB 2ip6 Pediococcus pentosaceus Secreted 1 0 0.6 ± 2.6 72 ± 23 -2.2
2.1.60.02. Lasiocepsin 2mbd Lasioglossum laticeps Secreted 1 0 0.6 ± 1.3 47 ± 15 -2.5
2.1.29.03. Apolipoprotein C-I, peptide 27-83 1ioj Homo sapiens Secreted 1 0 0.6 ± 1.8 80 ± 16 -2.8
2.2.26.01. RUN and FYVE domain-containing protein 1 2yw8 Homo sapiens Endosome 1 0 0.7 ± 3.4 48 ± 38 -2.8
2.2.06.02. Prostaglandin-H2 D-isomerase, ligand-bound 3o22 Homo sapiens Endoplasm. reticulum 1 0 0.7 ± 1.2 78 ± 13 -2.4
3.4.10.01. Methanobactin 2xjh Methylosinus trichosporium Secreted 1 0 0.7 ± 0.7 67 ± 7 -2.9
2.2.15.01. Gamma-crystallin F 1m8u Bos taurus Secreted 1 0 0.7 ± 1.2 85 ± 4 -4.9
2.3.16.06. ADP-ribosylation factor-like protein 1 1moz Saccharomyces cerevisiae Golgi 2 0 0.7 ± 1.1 90 ± 6 -4.3
2.1.60.03. Cysteine-rich secretory protein 2 2cq7 Homo sapiens Secreted 1 0 0.7 ± 1.1 68 ± 5 -2.5
2.2.34.02. Omega-theraphotoxin-Hh1a 1y29 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 0.7 ± 1.3 83 ± 17 -2.7
2.4.16.01. Alpha-insect toxin Lqq3 1lqq Leiurus quinquestriatus quinquestriatus Secreted 1 0 0.8 ± 1.0 80 ± 6 -3.3
2.1.25.05. Aureocin A53 2n8o Staphylococcus aureus Secreted 1 0 0.8 ± 0.4 78 ± 6 -2.6
3.2.01.06. Theta-defensin 1 (RTD-1) 1hvz Macaca mulatta Secreted 1 0 0.8 ± 1.0 89 ± 4 -2.9
2.2.20.01. Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 3nsu Saccharomyces cerevisiae Eukaryo. plasma 1 0 0.8 ± 1.5 57 ± 12 -4.0
2.4.05.01. Sterol carrier protein 2 1pz4 Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.8 ± 5.0 37 ± 49 -1.3
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3b 5kar Mus musculus Secreted 1 0 0.8 ± 1.3 51 ± 4 -3.9
3.1.20.01. Alpha-conotoxin CnIA 1b45 Conus consors (Singed cone) Secreted 1 0 0.8 ± 0.8 80 ± 20 -2.1
2.1.19.01. Kappa-buthitoxin-Tt2b 2li3 Tityus trivittatus Secreted 1 0 0.8 ± 0.7 40 ± 6 -2.7
2.2.11.01. Protein kinase C alpha, complex with phosphatidyl serine 1dsy Rattus norvegicus Eukaryo. plasma 1 0 0.9 ± 1.5 18 ± 16 -3.0
2.3.06.11. Monoglyceride lipase MGLL, closed ligand-bound conformation 3pe6 Homo sapiens Eukaryo. plasma 1 0 0.9 ± 3.0 54 ± 28 -2.7
2.2.41.01. Oral alpha defensin 1 2k1i Macaca mulatta Secreted 1 0 0.9 ± 3.2 70 ± 15 -2.2
1.2.50.02. Nakanori protein 5h0q Grifola frondosa Eukaryo. plasma 1 0 0.9 ± 1.8 37 ± 15 -3.1
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 2 1zhy Saccharomyces cerevisiae Golgi 1 0 0.9 ± 0.4 87 ± 4 -4.7
3.4.13.01. T-cell-specific surface glycoprotein CD28, intracellular loop 2nae Mus musculus Eukaryo. plasma 1 0 0.9 ± 10.0 81 ± 3 -6.4
1.2.03.02. T-cell immunoglobulin and mucin domain-containing protein 2 2or7 Mus musculus Eukaryo. plasma 1 0 0.9 ± 0.7 54 ± 6 -3.3
2.3.08.02. Cytosolic phospholipase A2 delta, structure 2 5iz5 Homo sapiens Vesicle 1 0 1.0 ± 0.0 77 ± 0 -4.1
2.1.41.01. Phosphatidylinositol 4-kinase type 2-alpha, structure 2 4pla Homo sapiens Golgi 1 0 1.0 ± 1.7 49 ± 3 -2.8
3.1.02.09. Peptide (659-711) of platelet endothelial cell adhesion molecule 2ky5 Homo sapiens Eukaryo. plasma 1 0 1.0 ± 3.8 89 ± 3 -3.7
2.2.33.01. Hevein 1q9b Hevea brasiliensis (Para rubber tree) Secreted 1 0 1.0 ± 1.0 90 ± 11 -1.8
2.2.05.01. Azurin I 1rkr Alcaligenes xylosoxidans Bact. Gram-neg inner 1 0 1.0 ± 1.0 43 ± 7 -4.3
2.2.34.01. Conotoxin mr3e 2efz Conus marmoreus Secreted 1 0 1.0 ± 1.3 83 ± 25 -3.2
2.4.05.01. Sterol carrier protein 2-like 2 2qzt Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 1.0 ± 2.0 45 ± 12 -3.0
2.3.13.02. Phosducin/Transducin beta-gamma complex, conformation 3 1b9x Rattus norvegicus Eukaryo. plasma 3 0 1.0 ± 1.6 49 ± 12 -3.9
2.2.07.01. YceI-like protein 3q34 Pseudomonas syringae Bact. Gram-neg inner 2 0 1.0 ± 1.1 89 ± 2 -3.9
3.2.01.09. Peptidomimetic TWLKKRRWKKAK-D-Pro-P 2m7j Designed proteins Undefined 1 0 1.0 ± 1.7 75 ± 37 -2.7
2.3.06.19. PHB depolymerase PhaZ7, structure 2 4btv Pseudomonas lemoignei Secreted 1 0 1.0 ± 2.3 64 ± 35 -5.2
2.1.21.05. Matrix protein p15 1hek Equine infectious anemia virus Endosome 1 0 1.0 ± 2.8 76 ± 21 -2.6
2.2.20.01. Pleckstrin homology domain-containing family A member 6 (PLEKHA6) 2d9y Homo sapiens Eukaryo. plasma 1 0 1.0 ± 0.3 67 ± 1 -6.2
2.1.26.01. Colicin-E1 2i88 Escherichia coli Secreted 1 0 1.1 ± 3.3 58 ± 37 -1.7
2.2.06.02. Fatty acid binding protein 6, ileal (Gastrotropin) 3elz Danio rerio Eukaryo. plasma 1 0 1.1 ± 0.9 85 ± 6 -2.4
1.1.56.01. Inner membrane protein YejM, strain K12 5i5h Salmonella typhimurium Bact. Gram-neg inner 1 0 1.1 ± 1.6 65 ± 2 -3.6
2.4.16.03. Charybdotoxin 2crd Leiurus quinquestriatus hebraeus Secreted 1 0 1.1 ± 1.5 86 ± 15 -3.2
2.2.34.01. Omega-conotoxin SVIB 1mvj Conus striatus Secreted 1 0 1.1 ± 2.1 20 ± 24 -2.1
2.2.12.02. Rho GDP-dissociation inhibitor 1, complex with cell division control protein 42 1doa Homo sapiens Eukaryo. plasma 2 0 1.1 ± 1.3 87 ± 4 -3.1
3.1.29.01. Cathelin-related peptide SC5 (SMAP-29) 1fry Ovis aries Secreted 1 0 1.1 ± 0.8 18 ± 9 -3.5
2.1.10.01. Glycolipid transfer protein, structure 2 1wbe Bos taurus Eukaryo. plasma 1 0 1.1 ± 2.4 89 ± 8 -9.4
2.4.16.02. Lucifensin 2lld Lucilia sericata Secreted 1 0 1.1 ± 1.7 11 ± 12 -3.0
1.2.29.01. Septation ring formation regulator EzrA 4uy3 Staphylococcus aureus Bact. Gram-pos plas. 1 0 1.2 ± 2.8 44 ± 4 -3.0
3.1.11.01. Pancreatic hormone 1v1d Bos taurus Secreted 1 0 1.2 ± 3.0 79 ± 32 -1.9
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 1 1zhx Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.9 90 ± 7 -5.0
2.1.60.01. Potassium channel toxin ShK 1roo Stoichactis helianthus Secreted 1 0 1.2 ± 1.2 46 ± 8 -3.7
2.4.16.04. Defensin-like protein 1brz Pentadiplandra brazzeana Secreted 1 0 1.2 ± 1.2 83 ± 10 -3.6
2.2.12.01. Mite group 2 allergen Der f 2 1xwv Dermatophagoides farinae (American house dust mite) Secreted 1 0 1.2 ± 1.4 64 ± 10 -3.1
2.1.24.01. Saposin B (peptide 195-273), structure 1 1n69 Homo sapiens Lysosome 2 0 1.2 ± 1.0 58 ± 6 -2.4
2.3.16.06. ADP-ribosylation factor-like protein 8A 2h18 Homo sapiens Endosome 1 0 1.2 ± 3.6 58 ± 28 -2.6
2.2.06.02. Fatty acid-binding protein 2flj Locusta migratoria (Migratory locust) Eukaryo. plasma 1 0 1.2 ± 1.5 62 ± 10 -3.6
2.3.14.01. Retinaldehyde-binding protein 1, closed state 3hx3 Homo sapiens Eukaryo. plasma 1 0 1.2 ± 2.9 77 ± 32 -4.8
2.1.01.01. Phospholipase A2 homolog 1ppa Agkistridon piscivorus Secreted 1 0 1.2 ± 0.9 85 ± 8 -4.5
2.4.11.01. Viscotoxin B 1jmp Viscum album Secreted 1 0 1.2 ± 1.4 52 ± 13 -3.2
2.4.07.01. PX domain of serine/threonine-protein kinase Sgk3 1xte Homo sapiens Endosome 1 0 1.2 ± 1.4 77 ± 11 -2.9
3.1.22.01. Antifungal peptide 2mp9 Cenchritis muricatus Secreted 1 0 1.2 ± 1.5 90 ± 26 -3.7
2.1.19.01. Antimicrobial peptide Tk-Amp-X2 2m6a Hordeum vulgare Secreted 1 0 1.2 ± 1.0 65 ± 7 -3.4
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 3 4jch Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.2 88 ± 1 -6.0
1.2.32.01. Fatty-acid peroxygenase 1izo Bacillus subtilis Bact. Gram-pos plas. 1 0 1.2 ± 0.3 76 ± 1 -5.5
2.1.19.01. Ribosome-inactivating protein luffin P1 2l37 Luffa aegyptiaca Secreted 1 0 1.3 ± 0.9 80 ± 7 -3.3
2.3.11.01. Ferrochelatase, conformation 2 (with porphyrin bound) 4klr Homo sapiens Mitochon. inner 2 0 1.3 ± 0.0 90 ± 1 -8.4
2.2.06.02. Myelin P2 protein 1yiv Equus caballus Eukaryo. plasma 1 0 1.3 ± 1.7 53 ± 11 -4.8
2.2.05.01. Plastocyanin 2plt Chlamydomonas reinhardtii Thylakoid 1 0 1.3 ± 1.5 21 ± 18 -2.0
3.1.24.01. Penaeidin-3a 1ueo Litopenaeus vannamei (Whiteleg shrimp) Secreted 1 0 1.3 ± 3.5 89 ± 2 -5.5
2.4.16.07. Diapause-specific peptide 2e2f Gastrophysa atrocyanea (Leaf beetle) Secreted 1 0 1.3 ± 1.0 30 ± 10 -4.2
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 1 4b2z Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.3 ± 1.3 86 ± 6 -4.6
2.2.34.02. Mu-agatoxin-Aa1a 1eit Agelenopsis aperta Secreted 1 0 1.3 ± 1.5 59 ± 10 -3.1
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform 3hhm Homo sapiens Eukaryo. plasma 2 0 1.3 ± 0.5 78 ± 1 -5.5
2.4.19.01. Protein CutA 1osc Rattus norvegicus Eukaryo. plasma 3 0 1.3 ± 0.3 90 ± 1 -5.5
3.1.20.01. Alpha-conotoxin GID 1mtq Conus geographus (Geography cone) Secreted 1 0 1.3 ± 2.5 78 ± 28 -2.4
3.2.01.07. Cys-free protegrin analogue 2mq2 Designed proteins Secreted 1 0 1.3 ± 1.1 61 ± 19 -3.5
1.3.25.01. Gamma-hemolysin prepore, hetero-octamer (A+B) 4p1y Staphylococcus aureus Secreted 8 0 1.3 ± 1.0 85 ± 2 -7.8
2.3.29.01. Undecaprenyl pyrophosphate synthase 2d2r Helicobacter pylori Bact. Gram-neg inner 2 0 1.3 ± 0.9 78 ± 1 -4.5
2.2.20.01. PH domain containing retinal protein 1 2d9v Mus musculus Eukaryo. plasma 1 0 1.3 ± 1.3 58 ± 14 -5.1
2.4.16.09. S-locus pollen protein 1ugl Brassica campestris (Field mustard) Secreted 1 0 1.3 ± 0.6 51 ± 5 -3.4
3.1.05.03. LAK160-P7 2l96 Designed proteins Undefined 1 0 1.4 ± 0.9 88 ± 5 -2.7
2.3.19.01. Cytotoxin L 2vkh Clostridium sordellii Secreted 1 0 1.4 ± 2.0 51 ± 17 -4.5
2.2.14.01. Retinoschisin 3jd6 Homo sapiens Eukaryo. plasma 8 0 1.4 ± 0.1 90 ± 0 -19.5
2.2.20.01. Oxysterol binding protein-related protein 11 2d9x Homo sapiens Eukaryo. plasma 1 0 1.4 ± 1.7 55 ± 18 -3.1
2.2.27.01. Ras association domain-containing protein 5, C1 domain 1rfh Mus musculus Eukaryo. plasma 1 0 1.4 ± 0.9 16 ± 6 -3.7
2.2.11.01. Phosphatidylinositide 3-kinase C2 alpha 2b3r Mus musculus Eukaryo. plasma 2 0 1.4 ± 1.5 88 ± 16 -4.4
2.3.12.01. Myotubularin-related protein 2, dimer 1m7r Homo sapiens Eukaryo. plasma 2 0 1.4 ± 0.3 89 ± 0 -6.4
2.2.07.01. Lipocalin BcnA 5ixh Burkholderia cepacia Bact. Gram-neg inner 1 0 1.4 ± 2.6 28 ± 29 -1.7
2.2.12.01. Mite group 2 allergen Der p 2 1ktj Dermatophagoides pteronyssinussearch Secreted 1 0 1.4 ± 1.3 65 ± 9 -3.2
2.2.05.01. Plantacyanin 1f56 Spinacia oleracea Thylakoid 1 0 1.4 ± 1.5 11 ± 15 -2.0
1.2.53.01. Squalene synthase, conformation 3 3weh Homo sapiens Endoplasm. reticulum 1 0 1.4 ± 2.5 90 ± 26 -3.8
2.1.28.01. Heat-stable enterotoxin II 1ehs Escherichia coli Secreted 1 0 1.4 ± 1.1 64 ± 11 -6.0
2.2.05.01. Azurin iso-2 1cuo Methylomonas sp. Bact. Gram-neg inner 1 0 1.4 ± 1.6 69 ± 15 -4.3
2.2.11.01. Synaptotagmin-1, C2A domain (Calcium free) 3f00 Homo sapiens Eukaryo. plasma 1 0 1.4 ± 1.5 29 ± 18 -3.3
2.3.23.01. Beta-Ketoacyl synthase/Acyl transferase 1tqy Streptomyces coelicolor Bact. Gram-pos plas. 2 0 1.4 ± 0.2 83 ± 1 -4.9
2.1.08.01. Cytochrome c2 1co6 Rhodopseudomonas viridis Bact. Gram-neg inner 1 0 1.4 ± 0.7 78 ± 10 -3.3
2.1.60.03. Cysteine-rich secretory protein 2 2a05 Mus musculus Secreted 1 0 1.4 ± 1.8 52 ± 133 -2.8
2.2.58.01. Cone arrestin 1suj Ambystoma tigrinum (Tiger salamander) Eukaryo. plasma 1 0 1.4 ± 0.8 82 ± 12 -4.7
2.1.08.01. Cytochrome c551 451c Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 1.4 ± 0.9 85 ± 10 -5.4
2.2.20.01. PH domain of TAPP2 1v5p Mus musculus Eukaryo. plasma 1 0 1.4 ± 1.3 61 ± 5 -3.7
2.3.06.05. Copper inducible hydrolase YahD 3og9 Lactococcus lactis Bact. Gram-pos plas. 1 0 1.4 ± 1.1 33 ± 10 -4.0
2.2.41.01. Neutrophil defensin 3 1dfn Homo sapiens Secreted 2 0 1.4 ± 1.3 87 ± 15 -3.9
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 2 5iqw Pseudomonas aeruginosa Secreted 1 0 1.5 ± 0.2 24 ± 5 -4.8
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 2 4axd Arabidopsis thaliana Eukaryo. plasma 1 0 1.5 ± 0.1 88 ± 4 -4.0
1.2.03.08. HLA class II histocompatibility antigen, DM alpha chain 2bc4 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 0.7 21 ± 3 -4.7
3.2.01.03. Androctonin 1cz6 Androctonus australis (Sahara scorpion) Secreted 1 0 1.5 ± 2.8 89 ± 16 -3.2
2.3.06.12. Heroin esterase 1lzk Rhodococcus sp. Bact. Gram-pos plas. 1 0 1.5 ± 1.5 69 ± 9 -4.0
2.3.01.08. Endoglucanase H 2vi0 Clostridium thermocellum Bact. Gram-pos plas. 1 0 1.5 ± 1.3 36 ± 9 -3.8
2.1.18.01. Annexin GH1 1n00 Gossypium hirsutum Eukaryo. plasma 1 0 1.5 ± 2.0 70 ± 17 -3.7
2.3.16.06. ADP-ribosylation factor-like protein 5A 1z6y Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.9 66 ± 15 -4.0
2.2.20.01. RAC-gamma serine/threonine-protein kinase 2x18 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.1 53 ± 4 -3.8
2.2.33.01. Antimicrobial Peptide AMP-1.1a 2kus Stellaria media Secreted 1 0 1.5 ± 0.9 18 ± 27 -2.7
2.1.24.01. Saposin B (peptide 195-273), structure 2 4v2o Homo sapiens Lysosome 2 0 1.5 ± 1.0 51 ± 4 -3.2
2.2.20.01. Myosin X 3tfm Rattus norvegicus Endosome 1 0 1.5 ± 2.6 81 ± 5 -3.0
2.2.11.01. Rab3 interacting molecule 2 (RIM2), C2A domain 2bwq Rattus norvegicus Eukaryo. plasma 1 0 1.5 ± 1.6 41 ± 19 -1.8
2.2.32.01. ADP-ribosylating toxin CARDS, full-length 4tlw Mycoplasma pneumoniae Secreted 1 0 1.5 ± 1.4 47 ± 2 -4.8
2.4.42.01. Bactericidal permeability-increasing protein 1bp1 Homo sapiens Secreted 1 0 1.5 ± 2.4 51 ± 17 -4.3
2.1.21.03. Matrix protein p15 1mn8 Moloney murine leukemia virus Endosome 1 0 1.5 ± 1.8 65 ± 24 -3.5
2.2.26.01. LM-5 FYVE domain 1z2q Leishmania major Endosome 1 0 1.5 ± 1.5 22 ± 19 -3.4
2.2.41.01. Reptilian defensin 2b5b Caretta caretta Secreted 1 0 1.5 ± 0.4 73 ± 1 -4.1
2.3.18.01. Choline O-acetyltransferase 2fy2 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 2.2 87 ± 17 -5.2
2.4.16.02. Defensin MGD-1 1fjn Mytilus galloprovincialis (Mediterranean mussel) Secreted 1 0 1.5 ± 1.4 43 ± 12 -3.0
2.1.24.01. Pore-forming peptide ameobapore A 1of9 Entamoeba histolytica Undefined 1 0 1.5 ± 1.0 13 ± 18 -2.3
2.2.11.01. Multiple C2 and transmembrane domain-containing protein 2 (MCTP2) 2ep6 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.5 7 ± 15 -3.0
2.1.58.01. Serine/threonine-protein kinase pelle 1ik7 Drosophila melanogaster Eukaryo. plasma 1 0 1.5 ± 3.7 86 ± 0 -6.8
1.3.25.01. Necrotic enteritis toxin B 4i0n Clostridium perfringens Secreted 1 0 1.6 ± 2.4 38 ± 7 -4.3
2.3.14.01. Neurofibromin 2d4q Homo sapiens Eukaryo. plasma 1 0 1.6 ± 2.0 34 ± 19 -3.3
1.1.55.01. Bacterial polysaccharide co-polymerase FepE 3b8n Escherichia coli Bact. Gram-neg inner 9 0 1.6 ± 0.1 1 ± 0 -20.3
2.3.16.06. ADP-ribosylation factor-like protein 1 2x77 Leishmania major Eukaryo. plasma 1 0 1.6 ± 1.4 80 ± 5 -3.6
3.1.21.01. Cecropin-P1 2n92 Ascaris suum Secreted 1 0 1.6 ± 3.4 90 ± 0 -4.1
2.1.42.01. Mundticin KS immunity protein 2zrr Enterococcus mundtii Secreted 1 0 1.6 ± 1.5 72 ± 9 -3.2
2.2.05.01. Pseudoazurin 1pmy Methylobacterium extorquens Bact. Gram-neg inner 1 0 1.6 ± 1.4 45 ± 13 -4.3
1.2.26.01. Outer membrane lipoprotein Wza, water-soluble part 2w8h Escherichia coli Bact. Gram-neg outer 8 0 1.6 ± 0.2 1 ± 0 -22.1
2.2.02.03. Flavivirin protease NS2B 2wv9 Murray valley encephalitis virus Endoplasm. reticulum 1 0 1.6 ± 2.4 69 ± 8 -4.7
2.4.37.01. Monalysin 4mjt Pseudomonas entomophila Secreted 9 0 1.6 ± 0.0 90 ± 0 -13.5
2.1.42.01. Bacteriocin 2fu2 Streptococcus pyogenes Secreted 1 0 1.6 ± 1.1 77 ± 16 -3.7
2.2.41.04. Antimicrobial peptide LCI 2b9k Bacillus subtilis Secreted 1 0 1.6 ± 2.9 89 ± 19 -4.4
3.1.20.01. Alpha-conotoxin GIA 1not Conus geographus (Geography cone) Secreted 1 0 1.6 ± 1.5 89 ± 20 -2.3
2.2.11.01. Synaptotagmin-1, C2B domain (Calcium-bound) 4v11 Homo sapiens Eukaryo. plasma 1 0 1.6 ± 2.3 40 ± 7 -3.2
2.1.29.01. Apolipoprotein E 1ya9 Mus musculus Secreted 1 0 1.6 ± 1.4 85 ± 11 -4.1
2.3.01.03. Alpha-amylase A 1wza Halothermothrix orenii Secreted 1 0 1.6 ± 0.4 80 ± 1 -6.7
2.2.33.01. Antimicrobial peptide 2 1mmc Amaranthus caudatus (Inca-wheat) Secreted 1 0 1.6 ± 1.2 46 ± 9 -3.9
3.1.20.01. O2-contryphan-Vc1 2n24 Conus victoriae (Queen Victoria cone) Secreted 1 0 1.6 ± 1.0 89 ± 22 -3.6
3.2.01.01. Alvinellacin 2llr Alvinella pompejana Secreted 1 0 1.6 ± 1.4 90 ± 5 -2.6
2.3.18.01. Carnitine O-octanoyltransferase 1nm8 Homo sapiens Mitochon. inner 1 0 1.7 ± 3.0 67 ± 15 -5.3
3.2.05.02. Sphingopyxin I 5jqf Sphingopyxis alaskensis Undefined 1 0 1.7 ± 1.8 40 ± 16 -3.7
2.1.08.01. Quinohemoprotein alcohol dehydrogenase ADH IIB 1kv9 Pseudomonas putida Bact. Gram-neg outer 1 0 1.7 ± 1.1 77 ± 22 -5.9
2.1.02.01. Seed lipoxygenase-B 2iuj Glycine max Eukaryo. plasma 1 0 1.7 ± 3.0 51 ± 15 -4.8
2.1.29.01. Apolipoprotein A-I, alternative structure of C-terminal domain 3r2p Homo sapiens Secreted 2 0 1.7 ± 1.6 87 ± 3 -4.1
2.2.17.01. 6.5 kDa glycine-rich antifreeze protein 2pne Hypogastrura harveyi Secreted 1 0 1.7 ± 0.2 89 ± 5 -7.7
2.2.03.01. Beta-secretase 1 2wf1 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 61 ± 6 -4.9
2.2.34.02. Kappa-hexatoxin-Hv1c 1dl0 Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 1.7 ± 1.3 53 ± 17 -3.1
2.2.20.01. PH domain of TAPP1 1eaz Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.6 87 ± 14 -3.0
1.2.22.01. Bcl-2-like protein 2 1o0l Homo sapiens Mitochon. outer 1 0 1.7 ± 2.3 86 ± 14 -3.7
2.2.11.01. Synaptotagmin-1, C2B domain (Calcium bound) 1uov Rattus norvegicus Eukaryo. plasma 1 0 1.7 ± 1.8 36 ± 13 -3.7
3.1.04.07. Peptide (119-148) of antifreeze protein Afp1 2lq2 Glaciozyma antarctica Undefined 1 0 1.7 ± 2.4 84 ± 6 -8.6
2.2.11.01. Rabphilin-3A 2k3h Mus musculus Eukaryo. plasma 1 0 1.7 ± 2.1 78 ± 16 -4.1
1.3.25.01. Gamma-hemolysin, component B 3lkf Staphylococcus aureus Secreted 1 0 1.7 ± 2.5 51 ± 11 -4.5
2.3.16.07. Ras-related protein Rab-7a 1vg8 Rattus norvegicus Endosome 1 0 1.7 ± 0.5 74 ± 3 -5.3
2.2.34.02. Beta-theraphotoxin-Tp2a 2n9t Thrixopelma pruriens Secreted 1 0 1.7 ± 0.1 60 ± 1 -7.2
1.2.03.04. Leukocyte immunoglobulin-like receptor subfamily B member 4 3p2t Homo sapiens Eukaryo. plasma 1 0 1.7 ± 0.4 84 ± 5 -5.9
2.2.34.12. Poneritoxin, omega-PONTX-Ae1a 2nbc Anochetus emarginatus Secreted 1 0 1.7 ± 1.8 72 ± 12 -2.5
2.1.01.01. Phospholipase A2, beta bungarotoxin A1 chain, complex with bungarotoxin 1bun Bungarus multicinctus Secreted 2 0 1.7 ± 0.9 79 ± 3 -3.8
2.2.36.01. Lactococcin 972 2lgn Lactococcus lactis Secreted 1 0 1.7 ± 2.8 56 ± 9 -3.3
2.3.06.05. Carboxylesterase 2 1auo Pseudomonas fluorescens Bact. Gram-neg inner 1 0 1.7 ± 3.0 33 ± 21 -3.4
2.4.06.01. StAR-related lipid transfer protein 5 2r55 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 47 ± 19 -4.8
2.3.21.01. Protein-tyrosine phosphatase, mitochondrial 1 3rgq Mus musculus Mitochon. inner 1 0 1.7 ± 0.7 54 ± 7 -4.9
2.3.06.01. Neuroligin-2 3bl8 Mus musculus Eukaryo. plasma 1 0 1.7 ± 1.6 32 ± 5 -4.1
1.2.06.01. Tumor necrosis factor ligand superfamily member 4 2hew Mus musculus Eukaryo. plasma 3 0 1.7 ± 0.3 90 ± 0 -7.9
2.2.20.01. Oxysterol-binding protein-related protein 8 1v88 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 78 ± 4 -4.6
2.2.34.02. Mu-cyrtautoxin-As1a 2m36 Apomastus schlingeri Secreted 1 0 1.7 ± 1.0 49 ± 35 -3.2
2.2.34.01. Conotoxin Gm9 1ixt Conus gloriamaris (Glory-of-the-Seas cone) Secreted 1 0 1.7 ± 1.7 85 ± 17 -3.0
2.1.01.01. Phospholipase A2 isoform 4 1yxh Naja sagittifera Secreted 1 0 1.7 ± 0.5 81 ± 2 -5.2
2.4.16.01. Neurotoxin BmK-M10 2kbk Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 1.7 ± 1.0 73 ± 14 -2.4
3.1.30.01. Lactoferrin-based peptide, 21-67 1z6v Homo sapiens Secreted 1 0 1.7 ± 1.4 84 ± 3 -4.9
3.1.11.02. Extendin-4 1jrj Heloderma suspectum Secreted 1 0 1.7 ± 0.8 79 ± 8 -5.0
2.4.16.01. Alpha-mammal toxin AaH2 1aho Androctonus australis (Sahara scorpion) Secreted 1 0 1.7 ± 1.0 64 ± 17 -3.4
2.2.20.01. Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 2da0 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 2.5 64 ± 20 -2.5
3.1.15.01. Sakacin P 1ohm Lactobacillus sake Secreted 1 0 1.8 ± 1.1 90 ± 11 -4.4
3.1.20.01. Conotoxin Ar1446 2m61 Conus araneosus Secreted 1 0 1.8 ± 0.8 82 ± 6 -4.0
2.2.05.01. Plastocyanin 9pcy Phaseolus vulgaris Thylakoid 1 0 1.8 ± 1.6 18 ± 19 -1.9
2.3.06.01. Acetylcholinesterase 1ea5 Torpedo californica Eukaryo. plasma 1 0 1.8 ± 1.1 34 ± 5 -4.7
2.4.28.01. Phenazine biosynthesis protein PhzF 1s7j Enterococcus faecalis Undefined 1 0 1.8 ± 0.7 77 ± 2 -4.3
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4-like 2nsq Homo sapiens Eukaryo. plasma 1 0 1.8 ± 1.1 85 ± 5 -3.3
2.2.34.05. Tachystatin-B1 2dcv Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 1.8 ± 1.1 5 ± 9 -5.9
2.3.01.09. Arabinogalactan endo-1,4-beta-galactosidase 1hjq Humicola insolens (Soft-rot fungus) Secreted 1 0 1.8 ± 1.4 86 ± 7 -3.7
2.2.27.01. Kinase supressor of Ras, Ksr 1kbf Mus musculus Eukaryo. plasma 1 0 1.8 ± 1.0 63 ± 11 -5.4
2.1.26.01. Colicin A channel-forming domain 1col Escherichia coli Secreted 1 0 1.8 ± 1.0 43 ± 11 -3.2
2.2.21.04. Cytolethal distending toxin complex 1sr4 Haemophilus ducreyi Bact. Gram-neg outer 3 0 1.8 ± 1.5 34 ± 7 -5.0
2.4.51.01. Heme acquisition protein HasA, dimer 4y4s Yersinia pseudotuberculosis Secreted 1 0 1.8 ± 1.1 83 ± 9 -4.2
2.3.06.02. MPT51/MPB51 antigen 1r88 Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 1.8 ± 1.0 28 ± 26 -3.9
1.2.39.01. Leucyl-cystinyl aminopeptidase, structure 2 5mj6 Homo sapiens Eukaryo. plasma 1 0 1.8 ± 1.4 76 ± 4 -3.5
2.4.16.04. Floral defensin-like protein 1 1n4n Petunia hybrida Secreted 1 0 1.8 ± 0.8 6 ± 9 -3.8
3.2.03.01. Maurocalcine 1s6w Scorpio maurus Secreted 1 0 1.8 ± 1.6 89 ± 21 -2.3
1.1.01.03. Ectodomain of G-protein coupled receptor Mth 1fjr Drosophila melanogaster Eukaryo. plasma 1 0 1.8 ± 1.5 56 ± 13 -4.3
2.1.60.01. Potassium channel toxin Bgk 1bgk Bunodosoma granulifera Secreted 1 0 1.8 ± 1.7 19 ± 27 -2.9
1.2.38.02. Lysozyme 3hde Enterobacteria phage p21 Secreted 1 0 1.8 ± 1.4 55 ± 10 -4.7
2.3.06.01. Bile-salt activated lipase, structure 1 1f6w Homo sapiens Secreted 1 0 1.8 ± 0.5 81 ± 10 -5.1
3.4.09.01. Granin 1lv4 Homo sapiens Secreted 1 0 1.8 ± 0.4 81 ± 3 -6.8
2.1.08.01. Mono-heme c-type cytochrome ScyA 1kx7 Shewanella putrefaciens Bact. Gram-neg inner 1 0 1.8 ± 1.1 72 ± 12 -3.2
2.2.01.01. F18 fimbrial adhesin AC, FedF 4b4q Escherichia coli Secreted 1 0 1.8 ± 2.6 81 ± 20 -3.4
2.3.06.01. Neuroligin-1, complex with human neurexin-1-alpha 3b3q Mus musculus Eukaryo. plasma 2 0 1.8 ± 1.0 81 ± 1 -3.6
2.3.06.16. Lipase lip1 4opm Acinetobacter baumannii Secreted 1 0 1.8 ± 1.0 41 ± 3 -4.4
2.1.24.01. Saposin-like protein 5 2jsa Caenorhabditis elegans Secreted 1 0 1.8 ± 2.2 47 ± 0 -3.7
3.2.10.01. PawS derived peptide 20 2ndn Zinnia haageana Secreted 1 0 1.8 ± 0.7 83 ± 11 -4.6
2.2.41.01. Defensin-like peptide 1 1b8w Ornithorhynchus anatinus Secreted 1 0 1.8 ± 0.6 84 ± 2 -4.4
2.2.34.02. Robustoxin 1qdp Atrax robustus Secreted 1 0 1.8 ± 1.9 86 ± 18 -5.0
1.2.32.01. Cholesterol 7-alpha-monooxygenase (P450 7A1) 3dax Homo sapiens Endoplasm. reticulum 1 0 1.8 ± 1.9 69 ± 8 -3.9
2.1.20.01. Osteocalcin 4mzz Bos taurus Secreted 1 0 1.8 ± 1.1 43 ± 8 -3.0
2.3.01.04. Hyaluronidase 1fcq Apis mellifera Secreted 1 0 1.9 ± 2.7 36 ± 13 -3.7
3.1.02.03. Juxtamembrane helix of ATP synthase subunit b 2khk Escherichia coli Bact. Gram-neg inner 1 0 1.9 ± 0.1 85 ± 3 -3.9
2.1.35.01. Protein kinase C and casein kinase substrate 3lll Mus musculus Vesicle 2 0 1.9 ± 0.4 88 ± 1 -5.4
3.1.11.02. Extendin-4, with extracellular domain of glucagon-like peptide-1 GPCR 3c59 Heloderma suspectum Secreted 2 0 1.9 ± 0.2 64 ± 0 -6.5
1.2.03.07. Netrin receptor UNC5B 3g5b Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 2.5 90 ± 14 -8.5
3.1.05.03. Human platelet factor 4 based peptide, 56-70, modified 1djf Designed proteins Undefined 1 0 1.9 ± 1.4 87 ± 8 -4.9
2.2.06.02. Retinol-binding protein 2 1opb Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 1.4 25 ± 7 -3.6
2.3.16.07. Ras-related protein Rab-9A 1wms Homo sapiens Eukaryo. plasma 1 0 1.9 ± 0.8 48 ± 7 -5.0
3.2.02.02. Chi-conotoxin Ar1248 2m62 Conus araneosus Secreted 1 0 1.9 ± 1.0 78 ± 12 -3.0
2.2.39.01. Erabutoxin b 3ebx Laticauda semifasciata (Black-banded sea krait) Secreted 1 0 1.9 ± 1.4 47 ± 11 -4.3
2.4.16.01. Tx10 alpha-like toxin 1kv0 Buthus martensii Secreted 1 0 1.9 ± 1.1 83 ± 11 -4.6
2.2.20.01. Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 4a6f Saccharomyces cerevisiae Eukaryo. plasma 1 0 1.9 ± 1.6 62 ± 4 -6.1
2.3.05.03. D-amino-acid oxidase 1ve9 Sus scrofa Peroxisome 2 0 1.9 ± 2.5 88 ± 4 -4.8
2.3.06.06. Triacylglycerol lipase 1lgy Rhizopus niveus Secreted 1 0 1.9 ± 1.8 33 ± 16 -4.8
2.4.16.04. Defensin 1ti5 Vigna radiata (Mung bean) Secreted 1 0 1.9 ± 2.4 62 ± 16 -3.0
2.4.51.01. Heme acquisition protein HasA 1b2v Serratia marcescens Secreted 1 0 1.9 ± 1.6 18 ± 18 -3.3
2.2.06.02. Intestinal fatty acid binding protein, structure 4 2mo5 Homo sapiens Eukaryo. plasma 1 0 1.9 ± 1.3 59 ± 6 -3.4
2.2.34.09. Psi-conotoxin PIIIE 1as5 Conus purpurascens (Purple cone) Secreted 1 0 1.9 ± 1.3 87 ± 11 -3.6
3.1.34.01. Conantokin-R1-B 2mzm Conus rolani Secreted 1 0 1.9 ± 0.7 81 ± 8 -2.9
2.3.06.17. Group XV phospholipase A2 4x90 Homo sapiens Lysosome 1 0 1.9 ± 0.5 56 ± 1 -7.3
3.4.09.01. Granin, cyclic analogue 1n2y Bos taurus Secreted 1 0 1.9 ± 2.1 71 ± 16 -3.4
2.1.01.01. Snake phospholipase A2 homolog 2, group II 2q2j Bothrops pirajai Secreted 1 0 1.9 ± 1.2 89 ± 9 -5.6
2.1.36.01. Endoplasmic reticulum oxidoreductin, a mutant 3m31 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.9 ± 1.2 27 ± 9 -6.2
2.2.20.01. Rho guanine nucleotide exchange factor 9, conformation 1 4mt7 Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 2.6 52 ± 14 -3.9
2.2.06.01. Retinol binding protein, plasma isoform 1iiu Gallus gallus Secreted 1 0 1.9 ± 1.8 35 ± 17 -4.4
2.4.10.01. Synapsin I 1auv Bos taurus Vesicle 1 0 1.9 ± 1.1 86 ± 11 -5.2
2.2.34.01. Mu-conotoxin GS 1ag7 Conus geographus (Geography cone) Secreted 1 0 1.9 ± 1.0 68 ± 15 -2.6
3.1.20.01. Alpha-conotoxin ImI 1e75 Conus imperialis (Imperial cone) Secreted 1 0 1.9 ± 0.9 80 ± 15 -3.7
3.4.02.02. Mersacidin, structure in methanol solution 1mqx Bacillus sp. Secreted 1 0 1.9 ± 1.3 87 ± 15 -2.9
2.3.06.19. Lipase A 1isp Bacillus subtilis Secreted 1 0 1.9 ± 0.8 59 ± 12 -5.2
2.1.01.01. Phospholipase A2, group IB 1g4i Bos taurus Secreted 1 0 1.9 ± 0.5 87 ± 4 -7.4
2.2.06.01. Complement component C8 gamma chain 1lf7 Homo sapiens Secreted 1 0 1.9 ± 2.2 43 ± 12 -2.6
2.2.16.01. Lipoprotein lppX 2byo Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 1.9 ± 1.7 80 ± 13 -4.8
2.2.34.02. U1-theraphotoxin-Ba1b 2kgh Brachypelma ruhnaui (Mexican golden redrump tarantula) Secreted 1 0 1.9 ± 2.5 83 ± 25 -1.9
2.3.06.01. Neuroligin-4, X-linked, complex with neurexin 1-beta 2xb6 Homo sapiens Eukaryo. plasma 2 0 1.9 ± 3.0 84 ± 11 -3.3
2.2.20.01. Son of sevenless homolog 1 (SOS-1) 1xd4 Homo sapiens Eukaryo. plasma 1 0 1.9 ± 3.0 79 ± 2 -4.5
3.2.10.01. PawS derived peptide 21 2ndm Zinnia haageana Secreted 1 0 1.9 ± 1.2 83 ± 16 -3.7
1.2.39.01. Endoplasmic reticulum aminopeptidase 1 3mdj Homo sapiens Endoplasm. reticulum 1 0 1.9 ± 3.6 63 ± 10 -4.6
2.1.20.01. Coagulation factor IX 1pfx Sus scrofa Eukaryo. plasma 2 0 1.9 ± 6.0 84 ± 10 -3.9
1.2.36.01. Hemagglutinin-neuraminidase glycoprotein 1v3e Human parainfluenza virus 3 Eukaryo. plasma 2 0 1.9 ± 0.4 81 ± 34 -6.5
2.4.16.08. Hydramacin-1 2k35 Hydra vulgaris Secreted 1 0 2.0 ± 0.2 87 ± 2 -4.3
2.2.06.01. Neutrophil gelatinase-associated lipocalin 3fw5 Homo sapiens Secreted 1 0 2.0 ± 1.2 45 ± 9 -3.1
2.2.05.01. Plastocyanin 1bxv Synechocystis sp. Thylakoid 1 0 2.0 ± 1.6 36 ± 19 -2.6
2.2.07.01. Lipocalin BcnB 5ixg Burkholderia cepacia Bact. Gram-neg inner 1 0 2.0 ± 1.0 36 ± 5 -3.9
1.2.01.01. Receptor tyrosine-protein kinase erbB-3, extracellular domains 1m6b Homo sapiens Eukaryo. plasma 1 0 2.0 ± 1.6 45 ± 5 -3.9
2.1.36.01. Endoplasmic reticulum oxidoreductin 1rp4 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.0 ± 1.8 16 ± 9 -4.7
3.2.04.02. Bowman-Birk type proteinase inhibitor peptide 1gm2 Macrotyloma axillare Secreted 1 0 2.0 ± 1.9 59 ± 14 -3.5
2.4.06.01. Lipid transport protein Mln64 (StARD3) 1em2 Homo sapiens Endosome 1 0 2.0 ± 1.1 82 ± 12 -5.0
2.3.06.01. Acetylcholinesterase 4qww Bungarus fasciatus Secreted 1 0 2.0 ± 1.5 36 ± 32 -3.0
2.4.38.01. Ups1 transporter-Mdm35 complex, structure 1 4xiz Saccharomyces cerevisiae Mitochon. inner 2 0 2.0 ± 1.7 19 ± 13 -4.1
2.1.60.01. Aurelin 2lg4 Aurelia aurita Secreted 1 0 2.0 ± 0.9 50 ± 6 -4.4
2.2.11.01. Protein kinase C delta 1yrk Homo sapiens Eukaryo. plasma 1 0 2.0 ± 1.6 52 ± 19 -1.8
2.1.24.01. Saposin A (peptide 60-140) 2dob Homo sapiens Lysosome 1 0 2.0 ± 2.5 70 ± 29 -4.2
2.1.08.01. Cytochrome c2 1cxa Rhodobacter sphaeroides Bact. Gram-neg inner 1 0 2.0 ± 1.2 88 ± 13 -4.3
2.3.14.01. Retinaldehyde-binding protein 1, closed state, more complete structure 3hy5 Homo sapiens Eukaryo. plasma 1 0 2.0 ± 3.9 55 ± 17 -4.5
3.2.01.09. Cyclic beta-hairpin peptide 2m7i Designed proteins Secreted 1 0 2.0 ± 0.5 84 ± 8 -4.1
3.1.11.03. Obestatin 2jsi Mus musculus Secreted 1 0 2.0 ± 3.3 85 ± 13 -3.1
1.2.01.01. Fibroblast growth factor receptor 2 complex 3oj2 Homo sapiens Secreted 6 0 2.0 ± 0.4 81 ± 3 -5.4
1.2.03.02. SLAM family member 6 2if7 Homo sapiens Eukaryo. plasma 3 0 2.0 ± 3.3 88 ± 11 -7.1
3.2.10.01. PawS derived peptide 7 2lwu Designed proteins Undefined 1 0 2.0 ± 1.4 81 ± 10 -3.0
2.3.19.01. Toxin B 2bvl Clostridium difficile Secreted 1 0 2.0 ± 1.1 24 ± 14 -4.2
2.3.17.02. Folic acid synthesis protein FOL1 2bmb Saccharomyces cerevisiae Mitochon. inner 1 0 2.0 ± 0.6 31 ± 2 -5.8
2.2.20.01. Dynamin-2 2ys1 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 0.4 49 ± 3 -5.3
2.3.19.02. Histo-blood group ABO system transferase 2rj6 Homo sapiens Golgi 1 0 2.1 ± 1.3 77 ± 3 -7.1
2.4.50.01. Matrix protein, Indiana virus, complex with mRNA export factor 4owr Vesicular stomatitis virus Viral 1 0 2.1 ± 0.8 65 ± 2 -7.6
3.2.01.01. Arenicin-2 2jni Arenicola marina Secreted 1 0 2.1 ± 1.1 82 ± 15 -5.2
1.1.49.01. ATP-dependent zinc metalloprotease FtsH 1lv7 Escherichia coli Bact. Gram-neg inner 1 0 2.1 ± 1.0 80 ± 11 -4.3
3.4.04.03. Tridecaptin A1 2n5y Designed proteins Undefined 1 0 2.1 ± 1.0 89 ± 7 -3.9
2.2.34.09. Psi-conotoxin PIIIF 1jlp Conus purpurascens (Purple cone) Secreted 1 0 2.1 ± 1.1 72 ± 30 -3.1
2.1.25.02. Carnocyclin A 2kjf Carnobacterium maltaromaticum Secreted 1 0 2.1 ± 1.1 61 ± 12 -4.6
2.1.08.01. Mitochondrial cytochrome c 1hrc Equus caballus Mitochon. inner 1 0 2.1 ± 1.0 80 ± 16 -2.6
2.2.27.01. C1 domain of protein kinase C alpha 2eli Homo sapiens Eukaryo. plasma 1 0 2.1 ± 0.4 23 ± 4 -7.4
3.4.08.03. Oxytocin 1xy2 Bos taurus Secreted 1 0 2.1 ± 2.6 86 ± 12 -3.2
2.3.31.01. Sorbose-specific phosphotransferase enzyme IIB component 1nrz Klebsiella pneumoniae Bact. Gram-neg inner 1 0 2.1 ± 0.7 83 ± 3 -4.5
2.1.18.01. Annexin I 1hm6 Sus scrofa Vesicle 1 0 2.1 ± 0.9 88 ± 7 -5.6
3.2.01.07. Protegrin-2 2muh Sus scrofa Secreted 1 0 2.1 ± 3.3 88 ± 2 -3.2
2.1.02.01. Arachidonate 5-lipoxygenase 3o8y Homo sapiens Eukaryo. plasma 1 0 2.1 ± 1.0 89 ± 4 -3.8
2.2.60.01. Matrix protein VP40 1es6 Zaire ebolavirus Viral 1 0 2.1 ± 0.5 80 ± 3 -6.7
2.1.60.02. Potassium channel blocking domain of matrix metalloproteinase-23 2k72 Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 2.3 77 ± 22 -4.4
2.4.07.01. Bud emergence protein 1 2v6v Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.1 ± 1.2 75 ± 6 -5.1
3.1.04.08. Truncated superoxide dismutase 1 2mp3 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 83 ± 0 -6.3
1.2.44.01. Amyloid beta A4 protein (peptide 672-699) 1amb Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 87 ± 0 -3.2
2.3.06.12. Lipase/esterase 3bjr Lactobacillus plantarum Secreted 1 0 2.1 ± 0.2 72 ± 5 -7.0
2.1.18.01. Annexin V 1a8a Rattus norvegicus Eukaryo. plasma 3 0 2.1 ± 1.1 89 ± 10 -8.9
3.1.03.07. N-terminal peptide (24-58) of Disabled homolog 2 2lsw Homo sapiens Vesicle 1 0 2.1 ± 0.6 85 ± 5 -3.8
2.2.27.01. Beta-chimaerin 1xa6 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 1.7 65 ± 7 -5.1
3.1.11.05. Parathyroid hormone 1et1 Homo sapiens Secreted 1 0 2.1 ± 0.5 85 ± 3 -5.6
2.4.16.01. Alpha-toxin Cn12 1pe4 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.1 ± 2.3 17 ± 13 -3.1
3.1.21.06. Spinigerin 1zrv Pseudacanthotermes spiniger Secreted 1 0 2.1 ± 3.4 77 ± 5 -3.9
2.1.01.01. Snake phospholipase A2 crotoxin basic chain 2, group II 2qog Crotalus durissus terrificus Secreted 1 0 2.1 ± 1.1 84 ± 8 -7.2
2.3.18.01. Choline O-acetyltransferase, different conformation 1t1u Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 1.7 73 ± 15 -6.8
3.1.11.06. Parathyroid hormone-related peptide, structure 2 3ffd Homo sapiens Secreted 1 0 2.2 ± 1.5 89 ± 3 -5.1
2.2.20.01. PH domain of docking protein 2 2d9w Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.2 13 ± 17 -3.5
2.1.08.01. Cytochrome c peroxidase 1nml Marinobacter hydrocarbonoclasticus Bact. Gram-neg inner 1 0 2.2 ± 0.4 83 ± 0 -7.9
3.2.06.01. Paralytic peptide 1irr Bombyx mori Secreted 1 0 2.2 ± 1.9 74 ± 19 -3.3
2.2.34.07. Asteropsin B 2lzx Asteropus sp. Secreted 1 0 2.2 ± 1.7 90 ± 21 -3.3
1.2.03.03. Myelin protein P0 3oai Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.2 72 ± 6 -5.8
1.2.04.01. Integrin alpha-L, cytoplasmic domain (1113-1170) 2k8o Homo sapiens Eukaryo. plasma 1 0 2.2 ± 0.7 65 ± 3 -3.7
2.2.12.03. Immunogenic protein MPT63 1lmi Mycobacterium tuberculosis Secreted 1 0 2.2 ± 1.9 86 ± 7 -4.3
2.2.41.01. Alpha-defensin 4 1zmm Homo sapiens Secreted 1 0 2.2 ± 1.0 76 ± 10 -5.5
2.2.20.01. Rho guanine nucleotide exchange factor 4 2dx1 Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.2 80 ± 10 -3.6
1.2.43.06. Outer capsid protein VP4, dimer 2b4h Rotavirus A Viral 2 0 2.2 ± 0.2 4 ± 1 -8.3
1.1.49.01. ATP-dependent zinc metalloprotease FtsH 3kds Thermotoga maritima Bact. Gram-neg inner 6 0 2.2 ± 0.4 90 ± 0 -12.8
2.2.34.02. Mu-theraphotoxin-Hhn1b 1niy Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.2 ± 0.7 71 ± 6 -4.6
2.1.18.01. Annexin IV, monomeric state 1ann Bos taurus Eukaryo. plasma 1 0 2.2 ± 1.0 77 ± 3 -6.0
2.2.20.01. Fermitin family homolog 2 4f7h Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.4 72 ± 4 -4.2
3.2.06.01. Growth-blocking peptide 2dj9 Mamestra brassicae Secreted 1 0 2.2 ± 0.7 31 ± 4 -6.2
2.3.13.02. Phosducin/Transducin beta-gamma complex, conformation 2 2trc Rattus norvegicus Eukaryo. plasma 3 0 2.2 ± 1.0 62 ± 10 -4.9
2.1.24.01. Saposin D (peptide 405-486) 2rb3 Homo sapiens Secreted 1 0 2.2 ± 1.7 88 ± 10 -3.4
2.3.04.01. Sorbitol dehydrogenase 1k2w Rhodobacter sphaeroides Bact. Gram-neg inner 2 0 2.2 ± 0.3 89 ± 1 -4.4
2.2.11.01. Synaptotagmin-7 3n5a Mus musculus Vesicle 1 0 2.2 ± 2.3 30 ± 12 -4.1
2.1.61.01. Muramidase Tse3-Tsi3 complex, conformation 2 4luq Pseudomonas aeruginosa Bact. Gram-neg outer 2 0 2.2 ± 1.4 69 ± 5 -8.2
2.3.02.01. Phospholipase C-beta isoform 2 2zkm Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.9 38 ± 12 -3.6
3.2.01.08. Lactoferricin B, peptide 10-19 1y5c Bos taurus Secreted 1 0 2.2 ± 1.2 54 ± 11 -3.4
1.2.39.02. Matrilysin, structure 3 2mzh Homo sapiens Secreted 1 0 2.2 ± 1.6 67 ± 22 -6.4
3.2.01.07. Protegrin-1 1pg1 Sus scrofa Secreted 1 0 2.2 ± 0.4 72 ± 4 -4.2
2.1.01.01. Snake phospholipase A2, group I, isoform 2 1u4j Bungarus caeruleus Secreted 1 0 2.2 ± 0.6 83 ± 4 -8.5
2.2.34.01. Conotoxin TVIIA 1eyo Conus tulipa (Fish-hunting cone snail) Secreted 1 0 2.2 ± 0.7 74 ± 9 -4.6
2.2.11.01. Synaptotagmin-13 1wfm Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.9 88 ± 15 -4.5
2.2.20.01. PH domain of Src-associated adaptor protein 2 homologue 1u5f Mus musculus Eukaryo. plasma 2 0 2.2 ± 2.0 56 ± 12 -4.9
2.2.33.01. Antimicrobial peptide 1b 2lb7 Triticum kiharae (Wheat) Secreted 1 0 2.2 ± 0.7 89 ± 7 -2.5
3.2.02.02. Chi-conotoxin MrIB 1ieo Conus marmoreus Secreted 1 0 2.2 ± 1.1 45 ± 12 -1.9
2.3.13.03. Thiol-disulfide interchange protein DsbA 1u3a Escherichia coli Bact. Gram-neg inner 1 0 2.2 ± 1.4 86 ± 8 -4.2
1.2.50.01. Fragaceatoxin C, complex with lipids 4tsq Actinia fragacea (Strawberry anemone) Secreted 1 0 2.2 ± 0.9 38 ± 3 -15.5
2.2.11.01. Protein kinase C eta, C2 domain 2fk9 Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.1 57 ± 6 -5.0
2.4.16.04. Defensin Lc-def 2lj7 Lens culinaris Secreted 1 0 2.2 ± 0.9 22 ± 10 -3.9
2.4.11.01. Hellethionin D 1nbl Helleborus purpurascens Secreted 1 0 2.2 ± 0.9 45 ± 9 -7.4
2.1.24.01. Saposin-like protein Na-SLP-1 3s63 Necator americanus Secreted 1 0 2.2 ± 1.6 74 ± 10 -3.5
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4, complex with GRB10 3m7f Mus musculus Eukaryo. plasma 2 0 2.2 ± 2.0 76 ± 13 -2.7
1.2.33.02. Protoporphyrinogen oxidase 1sez Nicotiana tabacum Mitochon. inner 1 0 2.2 ± 1.0 50 ± 3 -7.0
2.4.34.01. Ice-structuring protein RD1 1ucs Lycodichthys dearborni Secreted 1 0 2.2 ± 1.0 67 ± 9 -5.5
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1t27 Rattus norvegicus Eukaryo. plasma 1 0 2.3 ± 1.9 12 ± 12 -4.1
1.2.43.01. Envelope glycoprotein, Zika virus, structure 5 5lbs Zika virus Viral 1 0 2.3 ± 2.5 62 ± 5 -4.7
3.1.12.01. Sarafotoxin-M 2ldf Atractaspis microlepidota microlepidota Secreted 1 0 2.3 ± 1.5 30 ± 35 -2.1
3.4.04.01. Daptomycin, Ca-free, different conformation 1t5m Streptomyces roseosporus Secreted 1 0 2.3 ± 1.3 33 ± 6 -7.9
2.1.20.01. Osteocalcin 1q8h Sus scrofa Secreted 1 0 2.3 ± 1.7 81 ± 17 -4.4
2.2.11.01. C2A domain of synaptotagmin-5 5h4y Homo sapiens Vesicle 1 0 2.3 ± 2.3 29 ± 11 -4.5
2.3.13.02. Phosducin/Transducin beta-gamma complex, conformation 1 1a0r Bos taurus Eukaryo. plasma 3 0 2.3 ± 1.0 50 ± 4 -7.4
2.4.27.01. Gamma-glutamylaminecyclotransferase 1vkb Mus musculus Undefined 1 0 2.3 ± 0.7 72 ± 4 -4.8
2.1.18.01. Annexin D1 1ycn Arabidopsis thaliana Eukaryo. plasma 1 0 2.3 ± 1.1 78 ± 14 -3.4
2.3.01.01. Glucosylceramidase 2vt0 Pan troglodytes Lysosome 1 0 2.3 ± 1.0 86 ± 5 -7.3
2.2.20.01. PH domain of muscle M-line assembly protein unc-89 1fho Caenorhabditis elegans Eukaryo. plasma 1 0 2.3 ± 1.2 25 ± 14 -4.3
2.4.16.01. Alpha-toxin CsE5 1nra Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.3 ± 1.2 89 ± 22 -4.3
2.1.21.01. Influenza virus matrix protein M1, structure 2 4pus Influenza virus Viral 2 0 2.3 ± 1.6 81 ± 3 -9.4
2.1.18.01. Annexin V 1hvf Homo sapiens Eukaryo. plasma 1 0 2.3 ± 1.5 79 ± 10 -5.4
2.2.12.01. Lymphocyte antigen 86 3mtx Gallus gallus Secreted 1 0 2.3 ± 1.6 69 ± 11 -2.4
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3a 5fc1 Mus musculus Secreted 1 0 2.3 ± 3.0 62 ± 17 -4.8
2.4.11.01. Viscotoxin A1 3c8p Viscum album Secreted 1 0 2.3 ± 0.9 45 ± 7 -4.9
2.2.12.05. Glucans biosynthesis protein G 1txk Escherichia coli Bact. Gram-neg inner 1 0 2.3 ± 0.7 80 ± 8 -5.1
2.1.02.01. 8R-Lipoxygenase, complete structure 3dy5 Plexaura homomalla Eukaryo. plasma 1 0 2.3 ± 1.5 88 ± 10 -3.2
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, delta isoform 2wxf Mus musculus Eukaryo. plasma 1 0 2.3 ± 1.8 89 ± 3 -5.3
2.4.06.01. Acyl-coenzyme A thioesterase 11 3fo5 Homo sapiens Endoplasm. reticulum 1 0 2.3 ± 1.4 57 ± 7 -3.9
2.4.11.01. Viscotoxin A2 1jmn Viscum album Secreted 1 0 2.3 ± 0.3 63 ± 8 -3.3
1.2.50.01. Sticholysin-1 2ks4 Stoichactis helianthus Secreted 1 0 2.3 ± 2.2 6 ± 24 -5.7
2.3.05.02. Adrenodoxin reductase of mitochondrial p450 systems, complex with adrenodoxin 1e6e Bos taurus Mitochon. inner 2 0 2.3 ± 1.0 11 ± 2 -4.1
3.1.21.01. Cecropin A (1-8) - magainin (1-12) hybrid 1d9j Hyalophora cecropia (Cecropia moth) Secreted 1 0 2.3 ± 0.9 90 ± 10 -6.4
2.3.06.05. Carboxylesterase 2h1i Bacillus cereus Bact. Gram-pos plas. 1 0 2.3 ± 1.8 32 ± 31 -3.6
2.1.01.03. Prokaryotic phospholipase A2 1kp4 Streptomyces violaceoruber Secreted 1 0 2.4 ± 1.3 42 ± 13 -5.6
2.2.34.11. Violacin 1 2fqa Viola odorata Secreted 1 0 2.4 ± 3.4 70 ± 46 -4.0
3.2.05.02. Astexin-1, structure 1 2lti Asticcacaulis excentricus Secreted 1 0 2.4 ± 1.0 85 ± 9 -3.6
2.2.20.01. Dual adaptor of phosphotyrosine and 3-phosphoinositides 1fao Homo sapiens Eukaryo. plasma 1 0 2.4 ± 2.0 59 ± 19 -3.9
2.3.05.02. Sulfide-quinone reductase 3h28 Aquifex aeolicus Bact. Gram-neg inner 3 0 2.4 ± 0.1 90 ± 0 -19.4
3.2.01.06. Retrocyclin-2 (HTD-2) 2atg Macaca mulatta Secreted 1 0 2.4 ± 0.6 87 ± 9 -5.6
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens Endosome 1 0 2.4 ± 1.6 88 ± 12 -4.6
2.2.34.02. Psalmotoxin-1 1lmm Psalmopoeus cambridgei (Trinidad chevron tarantula) Secreted 1 0 2.4 ± 1.6 71 ± 15 -4.4
3.2.01.01. Arenicin-1 2jsb Arenicola marina Secreted 1 0 2.4 ± 2.1 80 ± 11 -5.2
2.2.37.01. Primary amine oxidase, liver isozyme 1tu5 Bos taurus Secreted 2 0 2.4 ± 1.2 89 ± 0 -6.1
2.3.06.12. Esterase LipW 3qh4 Mycobacterium marinum Bact. Gram-pos plas. 1 0 2.4 ± 1.2 76 ± 32 -5.0
2.1.29.06. Perilipin-3 1szi Mus musculus Endosome 1 0 2.4 ± 2.3 61 ± 6 -4.1
2.1.18.01. Annexin II 1w7b Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.2 87 ± 18 -3.8
1.2.22.01. Activator of apoptosis harakiri, cytosolic helix 2l58 Homo sapiens Mitochon. outer 1 0 2.4 ± 4.0 88 ± 0 -8.5
2.3.08.01. Patatin-like protein, PlpD 5fqu Pseudomonas aeruginosa Secreted 2 0 2.4 ± 0.6 90 ± 3 -5.6
2.2.11.01. C2 domain of otoferlin 3l9b Rattus norvegicus Vesicle 1 0 2.4 ± 5.2 16 ± 33 -3.4
2.2.25.01. Superoxide dismutase [Cu-Zn] 1oal Photobacterium leiognathi Bact. Gram-neg inner 1 0 2.4 ± 0.9 77 ± 2 -6.8
2.2.34.02. Neurotoxin Hm-3 2mqu Heriaeus melloteei Secreted 1 0 2.4 ± 0.6 75 ± 11 -7.4
3.1.20.01. Alpha-conotoxin Vc1A 2h8s Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.8 59 ± 6 -2.5
2.4.11.01. Alpha-1-purothionin 2plh Triticum aestivum Secreted 1 0 2.4 ± 2.0 53 ± 17 -4.6
3.1.20.01. O2-contryphan-Vc2 5l34 Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.4 85 ± 8 -4.2
3.1.20.01. Alpha-conotoxin PIVA 1p1p Conus purpurascens (Purple cone) Secreted 1 0 2.4 ± 1.0 30 ± 11 -3.8
2.3.01.02. Dhurrinase 1v02 Sorghum bicolor Secreted 2 0 2.4 ± 0.5 89 ± 9 -5.1
2.1.01.01. Snake phospholipase A2, isoform 3 2osn Bungarus caeruleus Secreted 1 0 2.4 ± 0.6 84 ± 4 -5.8
2.2.34.02. Delta-amaurobitoxin-Pl1b 1v91 Pireneitega luctuosa (Tangled nest spider) Secreted 1 0 2.4 ± 0.9 35 ± 4 -5.7
1.2.50.01. Fragaceatoxin C, trimer 3zwj Actinia fragacea (Strawberry anemone) Secreted 3 0 2.4 ± 0.2 89 ± 4 -8.4
2.2.08.01. Osmotin 1pcv Nicotiana tabacum Secreted 1 0 2.4 ± 1.9 82 ± 19 -2.7
3.2.05.02. Caulonodin 2mlj Caulobacter sp. Secreted 1 0 2.4 ± 1.7 87 ± 15 -5.0
2.1.31.01. Colicin M, alternative orientation 2xmx Escherichia coli Secreted 1 0 2.4 ± 2.3 82 ± 4 -4.8
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form, mutant 4os0 Homo sapiens Endoplasm. reticulum 1 0 2.4 ± 1.0 77 ± 4 -3.1
2.2.11.01. Extended synaptotagmin-2, third C2 domain 2dmg Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.0 76 ± 5 -4.8
2.4.15.01. Protein Nef, complex with tyrosine-protein kinase SH3 domain (HIV HV1A2) 3rbb Human immunodeficiency virus type 1 Eukaryo. plasma 2 0 2.4 ± 1.1 84 ± 6 -4.2
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 1 2w61 Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.4 ± 2.3 60 ± 7 -5.4
2.4.34.01. Ice-structuring protein SP2(HPLC 1) 1ops Zoarces americanus Secreted 1 0 2.4 ± 1.4 60 ± 12 -4.8
1.2.01.01. Insulin-like growth factor 1 receptor 1p4o Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.0 37 ± 11 -5.1
2.1.01.01. Myotoxin 1mc2 Agkistrodon acutus Secreted 1 0 2.4 ± 0.1 80 ± 2 -9.4
2.2.06.02. Cellular retinol-binding protein II 1crb Rattus norvegicus Eukaryo. plasma 1 0 2.4 ± 1.7 52 ± 19 -5.3
2.2.34.02. S64 4b2v Sicarius dolichocephalus Secreted 1 0 2.5 ± 0.5 71 ± 2 -4.3
3.4.10.01. Methanobactin 4oz7 Methylosinus sporium Secreted 1 0 2.5 ± 1.4 86 ± 15 -4.5
2.2.11.01. Synaptotagmin-1 1rsy Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 1.6 24 ± 17 -4.1
2.2.16.01. Lipoprotein LprG 3mh9 Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 2.5 ± 2.7 47 ± 10 -3.0
2.2.34.03. Toxin Ptu1 1i26 Peirates turpis (Assassin bug) Secreted 1 0 2.5 ± 0.9 52 ± 7 -3.6
1.2.37.01. ADP-ribosyl cyclase 1 3f6y Homo sapiens Eukaryo. plasma 1 0 2.5 ± 2.4 51 ± 9 -6.3
2.3.06.15. Polyneuridine-aldehyde esterase 2wfm Rauvolfia serpentina (Serpentwood) Endoplasm. reticulum 1 0 2.5 ± 1.7 88 ± 3 -4.6
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 3 5fih Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.5 ± 0.6 89 ± 1 -5.3
2.2.11.01. Rabphilin-3A, C2B domain 2cm5 Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 2.0 56 ± 14 -4.1
2.4.07.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Homo sapiens Golgi 1 0 2.5 ± 1.3 56 ± 16 -4.8
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 2 4ph7 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.5 ± 0.9 75 ± 2 -6.4
2.3.24.01. Phosphatase YidA 1rkq Escherichia coli Undefined 1 0 2.5 ± 1.3 79 ± 9 -4.1
2.4.07.01. PX domain of sorting nexin GRD19, ligand-free 1ocs Saccharomyces cerevisiae Endosome 1 0 2.5 ± 1.1 88 ± 11 -5.4
2.1.29.01. Apolipoprotein E 2l7b Homo sapiens Secreted 1 0 2.5 ± 1.0 73 ± 8 -4.9
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform 1e7u Sus scrofa Eukaryo. plasma 1 0 2.5 ± 0.9 85 ± 3 -4.7
2.2.41.01. Gallinacin-7 5lcs Gallus gallus Secreted 1 0 2.5 ± 1.4 85 ± 5 -5.6
2.2.11.01. Synaptotagmin-4 1ugk Homo sapiens Eukaryo. plasma 1 0 2.5 ± 1.7 34 ± 11 -3.5
2.1.18.01. Annexin IV 1i4a Bos taurus Eukaryo. plasma 3 0 2.5 ± 1.1 89 ± 3 -7.7
2.2.20.01. Rho GTPase-activating protein 27 3pp2 Homo sapiens Eukaryo. plasma 1 0 2.5 ± 2.2 72 ± 14 -3.4
2.3.16.02. Translocation ATPase SecA 1tf5 Bacillus subtilis Bact. Gram-pos plas. 1 0 2.5 ± 1.1 64 ± 5 -7.0
2.4.16.04. Defensin-like protein 2 2n2r Raphanus sativus Secreted 1 0 2.5 ± 1.7 31 ± 24 -4.2
2.2.06.02. Adipocyte lipid-binding protein 1tow Homo sapiens Eukaryo. plasma 1 0 2.5 ± 1.7 51 ± 18 -4.5
3.2.02.02. T-2-conotoxin MrIA 2ew4 Conus marmoreus Secreted 1 0 2.5 ± 1.5 81 ± 19 -3.0
2.2.34.02. omega-Agatoxin 1agg Agelenopsis aperta Secreted 1 0 2.5 ± 1.4 57 ± 17 -5.0
3.1.20.01. Alpha-conotoxin EIVA 1pqr Conus ermineus Secreted 1 0 2.5 ± 1.3 14 ± 14 -3.4
2.2.20.01. Proto-oncogene vav, complex with Ras-related C3 botulinum toxin substrate 1 3bji Homo sapiens Eukaryo. plasma 2 0 2.5 ± 2.2 72 ± 14 -3.4
3.1.15.01. Curvacin-A 2a2b Lactobacillus curvatus Secreted 1 0 2.5 ± 1.3 34 ± 18 -6.7
3.1.05.03. VG16KRKP peptide, structure 1 2mxh Designed proteins Undefined 1 0 2.5 ± 2.4 82 ± 11 -3.2
1.2.17.02. Synaptobrevin homolog YKT6 3kyq Rattus norvegicus Vesicle 1 0 2.5 ± 2.0 53 ± 8 -4.9
2.3.17.02. Dihydropteroate synthase 1tx2 Bacillus anthracis Bact. Gram-pos plas. 2 0 2.5 ± 0.3 90 ± 2 -7.7
3.1.05.03. VG16KRKP peptide, structure 2 2n63 Designed proteins Undefined 1 0 2.5 ± 0.3 57 ± 4 -4.0
1.2.43.02. E1 envelope glycoprotein 3n41 Chikungunya virus Viral 1 0 2.5 ± 2.9 71 ± 7 -5.8
2.2.20.01. PH domain of oxysterol-binding protein homolog 3, fused with lysozyme 4iap Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.5 ± 2.3 81 ± 3 -3.6
2.2.20.01. FYVE, RhoGEF and PH domain-containing protein 6 1wgq Mus musculus Eukaryo. plasma 1 0 2.5 ± 1.8 68 ± 17 -3.2
2.1.01.01. Snake phospholipase A2 homolog bothropstoxin-1, group II 3i03 Bothrops jararacussu Secreted 1 0 2.5 ± 0.5 76 ± 5 -10.6
2.4.13.01. Oxysterol-binding protein homolog 4 (KES1), N-terminal helix removed 1zi7 Saccharomyces cerevisiae Golgi 1 0 2.5 ± 0.5 75 ± 8 -6.9
2.4.33.01. 72 kDa type IV collagenase, complex with inhibitor-2 1gxd Homo sapiens Eukaryo. plasma 2 0 2.5 ± 1.1 77 ± 4 -5.4
2.2.27.01. C1 domain of unc-13 homolog A 1y8f Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 1.9 16 ± 17 -2.9
2.3.16.08. Interferon-inducible GTPase 1 1tpz Mus musculus Endoplasm. reticulum 1 0 2.5 ± 2.0 37 ± 7 -5.0
3.1.03.06. 12 kDa heat shock protein 4axp Saccharomyces cerevisiae Eukaryo. plasma 1 1 2.5 ± 0.1 74 ± 0 -5.5
2.1.31.01. Colicin-M 3da4 Escherichia coli Bact. Gram-neg inner 1 0 2.5 ± 0.9 49 ± 11 -5.5
2.1.48.01. Glycerol dehydrogenase 1kq3 Thermotoga maritima Undefined 1 0 2.5 ± 1.8 80 ± 5 -4.3
1.2.39.01. Endoplasmic reticulum aminopeptidase 2 3se6 Homo sapiens Endoplasm. reticulum 1 0 2.5 ± 1.8 60 ± 21 -4.5
1.2.57.01. Reticulon-4 2ko2 Mus musculus Endoplasm. reticulum 1 0 2.5 ± 0.3 83 ± 1 -6.2
2.4.20.02. Arylamine N-acetyltransferase 1w5r Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 2.6 ± 0.5 82 ± 6 -6.2
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 1 2xar Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 1.6 69 ± 7 -6.1
2.2.11.01. Protein kinase C beta 3pfq Rattus norvegicus Eukaryo. plasma 1 0 2.6 ± 0.9 45 ± 5 -3.4
1.2.17.01. SNARE complex with synaptotagmin1 2n1t Rattus norvegicus Eukaryo. plasma 5 0 2.6 ± 2.9 42 ± 16 -4.6
2.2.39.01. Cardiotoxin-A1 (cytotoxin 1) 2cdx Naja atra Secreted 1 0 2.6 ± 1.4 85 ± 17 -6.9
3.1.13.01. Adrenomedullin 2l7s Homo sapiens Secreted 1 0 2.6 ± 0.7 90 ± 5 -6.7
3.2.05.02. Microcin J25, redesigned, version 2 2mmw Designed proteins Undefined 1 0 2.6 ± 3.5 90 ± 4 -3.7
2.3.16.07. GTP-binding protein Rheb 1xtq Homo sapiens Eukaryo. plasma 1 0 2.6 ± 0.6 76 ± 20 -5.1
3.2.01.09. Chignolin 5awl Designed proteins Undefined 1 0 2.6 ± 2.1 77 ± 28 -2.8
2.2.06.02. Retinoid-binding protein 7 1lpj Homo sapiens Eukaryo. plasma 1 0 2.6 ± 1.1 44 ± 13 -6.0
2.2.45.01. Pertactin autotransporter 1dab Bordetella pertussis Bact. Gram-neg outer 1 0 2.6 ± 1.1 73 ± 6 -5.9
2.4.16.04. Defensin-like protein 32 2mz0 Arabidopsis thaliana Secreted 1 0 2.6 ± 1.4 19 ± 8 -3.4
3.2.05.01. Sviceucin 2ls1 Streptomyces sviceus Secreted 1 0 2.6 ± 1.3 78 ± 5 -7.0
1.1.26.07. STAS domain of sulfate permease 4dgf Wolinella succinogenes Bact. Gram-neg inner 1 0 2.6 ± 0.5 51 ± 2 -7.0
2.1.01.01. Snake phospholipase A2, group I 1ozy Micropechis ikaheka Secreted 1 0 2.6 ± 1.0 85 ± 5 -9.0
2.2.34.10. Imperatoxin-A 1ie6 Pandinus imperator (Emperor scorpion) Secreted 1 0 2.6 ± 0.8 55 ± 13 -3.1
2.1.01.01. Snake phospholipase A2 natratoxin, group I 2osh Naja atra Secreted 1 0 2.6 ± 1.6 83 ± 11 -6.1
3.1.20.01. Alpha-conotoxin PIA 1zlc Conus purpurascens (Purple cone) Secreted 1 0 2.6 ± 1.3 59 ± 16 -4.3
2.3.16.01. Shikimate kinase 1e6c Erwinia chrysanthemi Bact. Gram-neg inner 2 0 2.6 ± 1.8 90 ± 12 -5.8
2.3.06.01. Acetylcholinesterase 5x61 Anopheles gambiae (African malaria mosquito) Eukaryo. plasma 1 0 2.6 ± 1.5 37 ± 4 -4.0
2.1.21.01. Influenza virus matrix protein M1, structure 1 1aa7 Influenza virus Viral 2 0 2.6 ± 0.8 89 ± 4 -5.6
2.3.06.12. Gibberellin receptor GID1A 2zsh Arabidopsis thaliana Nuclear inner 1 0 2.6 ± 1.2 89 ± 6 -5.0
2.1.01.01. Phospholipase A2 2not Notechis scutatus scutatus (Mainland tiger snake) Secreted 1 0 2.6 ± 1.5 73 ± 8 -3.9
2.1.01.01. Snake phospholipase A2, acidic 2, group I 1p7o Micropechis ikaheka Secreted 1 0 2.6 ± 0.5 90 ± 2 -9.4
2.2.52.01. Allene oxide cyclase 2 2brj Arabidopsis thaliana Chloroplast inner 3 0 2.6 ± 0.5 88 ± 5 -9.7
2.2.12.04. AP-2 complex 2vj0 Rattus norvegicus Vesicle 1 0 2.6 ± 2.0 80 ± 11 -4.8
1.1.71.01. Legionalla phosphoinositide phosphatase, SidP 4jza Legionella pneumophila Vacuole 1 0 2.6 ± 1.7 57 ± 7 -5.6
2.1.10.01. Accelerated-cell-death 11 apo-protein 4nt1 Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 2.0 85 ± 7 -5.4
1.2.44.01. Amyloid beta A4 protein (peptide 696-706) 1qcm Homo sapiens Eukaryo. plasma 1 0 2.6 ± 1.5 78 ± 17 -2.9
2.1.60.03. Natrin-1 1xx5 Naja atra Secreted 1 0 2.6 ± 2.4 60 ± 49 -5.2
2.2.34.02. U1-theraphotoxin-Hh1a 1i25 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.6 ± 0.2 79 ± 1 -5.1
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form 4ors Homo sapiens Endoplasm. reticulum 1 0 2.6 ± 0.8 71 ± 7 -3.7
2.2.39.01. Toxin B 1txa Ophiophagus hannah Secreted 1 0 2.6 ± 1.5 51 ± 16 -5.6
1.2.50.01. Fragaceatoxin C, monomer 3lim Actinia fragacea (Strawberry anemone) Secreted 1 0 2.6 ± 0.8 46 ± 15 -5.0
2.1.30.01. Membrane-integrating protein mistic, mstX 1ygm Bacillus subtilis Bact. Gram-pos plas. 1 0 2.6 ± 1.8 31 ± 6 -5.2
2.2.09.01. Kelch-like protein 7 3ii7 Homo sapiens Undefined 1 0 2.6 ± 1.8 90 ± 16 -6.5
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3a 5ebe Homo sapiens Secreted 1 0 2.6 ± 0.6 38 ± 1 -7.0
2.1.08.01. Cytochrome c551 1cor Pseudomonas stutzeri Bact. Gram-neg inner 1 0 2.6 ± 1.1 73 ± 12 -6.1
1.2.43.02. E1 envelope glycoprotein 1rer Semiliki forest virus Viral 3 0 2.6 ± 2.0 38 ± 5 -6.5
2.4.16.04. Flower-specific gamma-thionin-like protein 4uj0 Solanum lycopersicum Secreted 1 0 2.6 ± 0.9 19 ± 5 -4.8
2.4.06.03. S-norcoclaurine synthase 2vq5 Thalictrum flavum (Yellow meadow rue) Undefined 4 0 2.6 ± 0.3 90 ± 0 -7.0
2.4.16.03. Potassium channel toxin alpha-KTx 3.1 3odv Androctonus mauretanicus mauretanicus (Scorpion) Secreted 1 0 2.6 ± 0.9 84 ± 5 -5.1
2.1.01.01. Snake phospholipase A2, group II, neutral 1bjj Agkistrodon halys pallas Secreted 1 0 2.6 ± 0.7 86 ± 5 -8.4
2.2.10.01. High potential iron protein 1hpi Ectothiorhodospira vacuolata Bact. Gram-neg inner 1 0 2.7 ± 1.0 89 ± 12 -4.4
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4 3b7y Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.5 9 ± 6 -4.1
2.2.20.01. Son of sevenless homolog 1 (two domains) 1dbh Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.8 28 ± 19 -4.2
2.2.20.01. Ras-specific guanine nucleotide-releasing factor 2dtc Mus musculus Eukaryo. plasma 1 0 2.7 ± 0.4 64 ± 9 -6.3
2.3.09.01. Cytidylyltransferase 3hl4 Rattus norvegicus Eukaryo. plasma 2 0 2.7 ± 4.0 74 ± 8 -3.2
3.1.20.01. alpha-conotoxin MII 1mii Conus magus Secreted 1 0 2.7 ± 1.8 45 ± 19 -4.2
2.4.16.05. Plectasin 3e7r Pseudoplectania nigrella (Ebony cup) Secreted 1 0 2.7 ± 2.3 53 ± 17 -4.0
2.3.11.01. Ferrochelatase, conformation 1 1hrk Homo sapiens Mitochon. inner 2 0 2.7 ± 0.1 90 ± 0 -9.9
2.2.12.01. Lymphocyte antigen 96, structure 2 4g8a Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.3 67 ± 6 -3.8
2.3.06.06. Mono- and diacylglycerol lipase 5ch8 Penicillium cyclopium Secreted 1 0 2.7 ± 0.3 9 ± 7 -4.2
1.2.41.01. Acyl-CoA-binding protein 2cb8 Homo sapiens Peroxisome 1 0 2.7 ± 2.0 74 ± 29 -5.2
2.2.34.11. Kalata-B7 2jwm Oldenlandia affinis Secreted 1 0 2.7 ± 2.2 86 ± 28 -4.8
2.2.06.02. Myelin P2 protein 1pmp Bos taurus Eukaryo. plasma 1 0 2.7 ± 1.3 61 ± 13 -6.1
2.2.20.01. Rac-alpha serine/threonine kinase 1unq Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.0 67 ± 18 -3.9
2.1.18.01. Annexin III 1axn Homo sapiens Eukaryo. plasma 1 0 2.7 ± 0.8 77 ± 11 -5.7
2.1.01.01. Ammodytin L1 isoform 3ux7 Vipera ammodytes meridionalis Secreted 1 0 2.7 ± 0.3 82 ± 1 -13.2
2.1.54.01. Programmed cell death protein 10 3ajm Homo sapiens Golgi 2 0 2.7 ± 0.4 86 ± 7 -5.8
2.2.39.02. Mambalgin-2 2mfa Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 2.7 ± 2.5 76 ± 5 -6.4
2.1.42.01. Lactococcin-A immunity protein 5lfi Lactococcus lactis Secreted 1 0 2.7 ± 1.4 40 ± 9 -4.8
2.4.06.05. Thermoacidophile-specific fatty acid carrier 3w9k Sulfolobus tokodaii Archaebac. 1 0 2.7 ± 1.4 47 ± 4 -7.1
2.1.64.01. Envelope glycoprotein, ligand-binding domain 1 5e7x Talaromyces marneffei Eukaryo. plasma 1 0 2.7 ± 2.2 55 ± 13 -4.4
2.1.08.01. Cytochrome c552 1a8c Nitrosomonas europaea Bact. Gram-neg inner 1 0 2.7 ± 1.0 80 ± 11 -4.7
2.1.41.01. Phosphatidylinositol 3-kinase catalytic subunit type 3 3ls8 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 75 ± 9 -4.7
2.4.07.01. PX domain of sorting nexin-14 4bgj Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 72 ± 22 -4.3
3.2.01.01. Arenicin-2, dimer 2l8x Arenicola marina Secreted 2 0 2.7 ± 1.1 87 ± 4 -4.0
3.2.08.01. Peptide 35-42, alternate polymorph II 2y3l Homo sapiens Secreted 4 0 2.7 ± 1.4 78 ± 8 -6.0
2.2.45.02. Pectate lyase A 1pe9 Erwinia chrysanthemi Secreted 1 0 2.7 ± 0.4 81 ± 3 -6.4
2.1.01.01. Snake phospholipase A2 RV-7, group II 1oqs Daboia russellii siamensis Secreted 1 0 2.7 ± 1.1 87 ± 8 -7.9
2.1.29.01. Apolipoprotein A-I 2lem Mus musculus Secreted 1 0 2.7 ± 1.7 79 ± 2 -4.3
3.4.12.02. Thiostrepton, epimer form 2l2y Streptomyces azureus Secreted 1 0 2.7 ± 2.9 29 ± 9 -5.3
2.4.40.01. IpgB2 protein 3lxr Shigella flexneri Bact. Gram-neg inner 2 0 2.7 ± 0.4 75 ± 2 -6.7
2.3.01.07. Chitinase A 1nh6 Serratia marcescens Secreted 1 0 2.7 ± 1.3 80 ± 5 -6.1
2.2.14.02. SUN domain-containing protein 2 3unp Homo sapiens Nuclear outer 3 0 2.7 ± 0.1 20 ± 0 -5.3
1.2.03.09. Programmed cell death protein 1 3sbw Mus musculus Eukaryo. plasma 1 0 2.7 ± 0.9 89 ± 4 -5.9
2.1.29.02. Apolipoprotein A-II 2ou1 Homo sapiens Secreted 2 0 2.7 ± 1.2 87 ± 2 -17.7
2.2.05.01. Azurin 1xb8 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 2.7 ± 0.6 47 ± 4 -5.2
2.1.18.01. Annexin A2 4x9p Bos taurus Vesicle 1 0 2.7 ± 2.4 81 ± 12 -3.5
3.1.04.03. Viral protein R, peptide 13-33, different strain 1fi0 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 2.7 ± 1.2 88 ± 8 -8.6
2.2.22.01. Hydrophobin NC2, structure 2 4bwh Neurospora crassa Secreted 1 0 2.7 ± 3.1 85 ± 29 -4.5
2.4.50.01. Matrix protein, Indiana virus 1lg7 Vesicular stomatitis virus Viral 1 0 2.7 ± 0.4 82 ± 2 -7.3
2.3.06.06. Triacylglycerol lipase, closed (inactive) state 3tgl Rhizomucor miehei Secreted 1 0 2.7 ± 1.1 39 ± 7 -5.8
3.1.02.07. Sodium/hydrogen exchanger 1, TM helices 2kbv Homo sapiens Eukaryo. plasma 1 0 2.7 ± 6.9 74 ± 4 -4.9
1.2.51.01. Alkaline sphingomyelinase 5udy Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.3 84 ± 10 -4.5
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 2 2w62 Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.7 ± 0.5 90 ± 1 -6.1
2.2.41.01. Beta-defensin 3 1kj6 Homo sapiens Secreted 1 0 2.7 ± 1.3 18 ± 18 -5.1
2.1.18.01. Annexin XII 1dm5 Hydra vulgaris Eukaryo. plasma 3 0 2.7 ± 1.0 90 ± 7 -10.2
3.2.01.09. Transthyretin-derived peptide 5hpp Designed proteins Undefined 1 0 2.7 ± 1.6 83 ± 6 -5.2
2.2.27.01. C1 domanin of SH3 and cysteine-rich domain-containing protein 3 2db6 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 0.1 75 ± 0 -4.8
2.2.34.02. Huwentoxin-1 1qk6 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.7 ± 1.5 88 ± 11 -5.1
2.1.01.01. Phospholipase A2 homolog, taipoxin beta chain 3vbz Oxyuranus scutellatus scutellatus Secreted 1 0 2.8 ± 0.7 87 ± 2 -7.7
2.4.04.01. Beta-hemolysin 3i48 Staphylococcus aureus Secreted 1 0 2.8 ± 0.8 57 ± 5 -5.1
2.3.06.02. Antigen 85a 1sfr Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 2.8 ± 0.8 27 ± 9 -7.5
2.2.35.01. Anthrolysin O 3cqf Bacillus anthracis Secreted 1 0 2.8 ± 1.0 75 ± 1 -5.8
2.1.01.01. Myotoxin II 1y4l Bothrops asper Secreted 1 0 2.8 ± 0.8 76 ± 7 -10.3
3.1.11.02. Glucagon-like peptide 1, with extracellular GPCR domain 3iol Homo sapiens Secreted 2 0 2.8 ± 4.0 70 ± 1 -6.7
2.2.14.01. Lactadherin 3bn6 Bos taurus Secreted 1 0 2.8 ± 0.5 11 ± 4 -7.2
2.2.35.01. Streptolysin O 4hsc Streptococcus pyogenes Secreted 1 0 2.8 ± 3.5 15 ± 27 -5.1
2.4.51.01. Heme acquisition protein HasA, apoprotein 1ybj Serratia marcescens Secreted 1 0 2.8 ± 2.4 33 ± 9 -3.9
2.2.41.01. Beta-defensin 8 1e4r Mus musculus Secreted 1 0 2.8 ± 1.1 74 ± 19 -5.5
1.2.53.01. Squalene synthase, conformation 2 3wcf Homo sapiens Endoplasm. reticulum 1 0 2.8 ± 0.8 87 ± 3 -7.0
2.2.12.02. Rho GDP-dissociation inhibitor 2, complex with G-protein RAC2 1ds6 Homo sapiens Eukaryo. plasma 2 0 2.8 ± 1.0 82 ± 6 -5.5
2.2.20.01. Rho guanine nucleotide exchange factor 9 complex 2dfk Rattus norvegicus Eukaryo. plasma 2 0 2.8 ± 2.7 69 ± 3 -5.0
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 1 2q9f Homo sapiens Endoplasm. reticulum 1 0 2.8 ± 1.0 86 ± 7 -5.8
2.2.38.01. Colicin E3 1jch Escherichia coli Secreted 4 0 2.8 ± 0.3 89 ± 5 -8.8
2.2.39.01. alpha-Cobratoxin 1ctx Naja kaouthia Secreted 1 0 2.8 ± 1.7 29 ± 18 -4.6
2.2.11.01. Synaptotagmin-7 2d8k Homo sapiens Vesicle 1 0 2.8 ± 1.3 27 ± 16 -6.6
2.2.05.01. Plastocyanin 1b3i Prochlorothrix hollandica Thylakoid 1 0 2.8 ± 1.4 43 ± 18 -4.4
2.2.34.02. M-theraphotoxin-Gr1a 1lu8 Grammostola rosea (Chilean rose tarantula) Secreted 1 0 2.8 ± 0.9 69 ± 7 -7.2
2.2.34.01. Omega conotoxin TxVII 1f3k Conus textile Secreted 1 0 2.8 ± 1.4 57 ± 18 -4.5
2.4.07.01. NADPH oxidase organizer 1, PX domain 2l73 Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.9 72 ± 13 -5.1
2.4.16.04. Defensin 2 (PDF1) 2gl1 Vigna radiata (Mung bean) Secreted 1 0 2.8 ± 0.6 6 ± 4 -5.7
2.1.01.01. Snake phospholipase A2, group II 1jlt Vipera ammodytes meridionalis Secreted 1 0 2.8 ± 1.0 89 ± 7 -8.7
2.2.02.01. Exfoliative toxin B 1qtf Staphylococcus aureus Secreted 1 0 2.8 ± 1.9 81 ± 11 -5.8
2.1.33.01. DrrA protein, PtdIns(4) binding domain, complex with PtdIns(4) 4mxp Legionella pneumophila Vacuole 1 0 2.8 ± 2.6 59 ± 12 -4.5
2.4.43.01. Cell wall anchor protein of the T6SS system 4b62 Pseudomonas aeruginosa Bact. Gram-neg outer 1 0 2.8 ± 2.5 46 ± 36 -4.6
2.3.06.12. Carboxylesterase (EstA) 1jji Archaeoglobus fulgidus Archaebac. 1 0 2.8 ± 1.0 56 ± 22 -4.8
2.4.03.01. Tubby protein, ligand-free 1c8z Mus musculus Eukaryo. plasma 1 0 2.8 ± 0.9 89 ± 13 -5.8
2.4.16.01. Beta-mammal toxin Cn2 2yc1 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.8 ± 1.1 68 ± 9 -3.8
2.1.18.01. Annexin VI 1m9i Homo sapiens Eukaryo. plasma 1 0 2.8 ± 0.3 82 ± 0 -8.5
2.3.28.01. Aldo-keto reductase family 1 member C1 1qwk Caenorhabditis elegans Undefined 1 0 2.8 ± 1.0 66 ± 3 -6.3
1.2.03.02. Hepatitis A virus cellular receptor 2 homolog 3kaa Mus musculus Eukaryo. plasma 1 0 2.8 ± 2.0 55 ± 16 -5.5
2.3.06.17. Phosphatidylcholine-sterol acyltransferase, structure 3 5bv7 Homo sapiens Secreted 1 0 2.8 ± 3.1 76 ± 15 -6.1
2.2.12.02. Rho GDP-dissociation inhibitor 1 1qvy Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.7 53 ± 19 -5.1
2.1.24.01. NK-lysin 1nkl Sus scrofa Secreted 1 0 2.8 ± 1.5 37 ± 12 -5.4
3.4.02.03. Bovicin HJ50 2m8v Streptococcus equinus Secreted 1 0 2.8 ± 1.0 71 ± 8 -4.0
2.1.01.01. Acidic phospholipase A2 5 4rfp Trimeresurus stejnegeri Secreted 1 0 2.8 ± 0.3 81 ± 3 -7.1
2.1.03.01. Phospholipase C 1p6d Bacillus cereus Secreted 1 0 2.8 ± 1.0 52 ± 6 -8.4
2.1.01.01. Phospholipase A2 BnSP-7 1pa0 Bothrops neuwiedi pauloensis Secreted 1 0 2.8 ± 1.0 78 ± 10 -6.9
2.3.28.01. Aldo-keto reductase family 1 member C21 3fjn Mus musculus Undefined 1 0 2.8 ± 1.0 56 ± 3 -5.2
3.2.05.02. Astexin-4 2n6u Asticcacaulis excentricus Secreted 1 0 2.8 ± 1.1 41 ± 21 -3.8
2.2.34.07. Asteropsin A 3q8j Asteropus sp. Secreted 1 0 2.8 ± 1.7 75 ± 15 -3.0
2.4.20.02. Arylamine N-acetyltransferase 1w4t Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 2.8 ± 0.4 82 ± 1 -5.8
1.2.52.01. Cytochrome c-type biogenesis protein CcmE 1sr3 Escherichia coli Bact. Gram-neg inner 1 0 2.8 ± 2.7 59 ± 6 -2.2
2.1.03.01. Alpha-toxin 1olp Clostridium absonum Secreted 1 0 2.8 ± 1.8 62 ± 11 -6.1
3.1.20.01. Alpha-conotoxin S1 1qmw Conus striatus Secreted 1 0 2.8 ± 2.6 43 ± 17 -2.5
3.1.08.01. Antifreeze protein A 1wfb Pseudopleuronectes americanus Secreted 1 0 2.8 ± 1.0 88 ± 1 -10.1
1.2.01.01. Macrophage colony-stimulating factor 1 receptor 3bea Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.5 54 ± 19 -4.2
3.2.01.08. Lactoferricin B, peptide 38-49 1y58 Bos taurus Secreted 1 0 2.9 ± 1.4 86 ± 18 -3.7
1.2.05.02. Internalin C 1xeu Listeria monocytogenes Bact. Gram-pos plas. 1 0 2.9 ± 1.3 81 ± 0 -4.1
1.2.51.01. Bis(5-adenosyl)-triphosphatase ENPP4 4lqy Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 81 ± 12 -5.5
2.4.16.01. Beta-toxin CsEI 1b3c Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.9 ± 1.2 70 ± 7 -3.9
2.2.41.01. Alpha-defensin cryptdin-4 1tv0 Mus musculus Secreted 1 0 2.9 ± 1.4 67 ± 13 -4.5
2.2.34.01. Omega conotoxin SO3 1fyg Conus striatus Secreted 1 0 2.9 ± 1.1 76 ± 18 -3.5
2.2.06.02. Intestinal fatty acid binding protein, structure 1 1kzw Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.3 61 ± 12 -4.1
2.3.16.06. ADP-ribosylation factor 1 (ARF1) 2k5u Saccharomyces cerevisiae Golgi 1 0 2.9 ± 1.6 24 ± 18 -5.5
3.1.02.16. Peptide 211-263 of YscU protein 2ml9 Yersinia pseudotuberculosis Bact. Gram-neg inner 1 0 2.9 ± 1.8 82 ± 5 -6.6
2.2.42.01. Matrix protein 2vqp Human respiratory syncytial virus Eukaryo. plasma 1 0 2.9 ± 1.1 86 ± 10 -6.1
2.3.06.12. Carboxylesterase 3wj2 Thermoplasma acidophilum Secreted 1 0 2.9 ± 1.9 81 ± 9 -5.1
2.2.11.01. Protein kinase C epsilon 1gmi Rattus rattus Eukaryo. plasma 1 0 2.9 ± 1.2 46 ± 15 -5.9
1.3.25.01. Gamma-hemolysin, heterodimer of components A and B 2qk7 Staphylococcus aureus Secreted 2 0 2.9 ± 2.0 83 ± 11 -5.7
1.2.43.06. Outer capsid protein VP4, trimer 2b4i Rotavirus A Viral 3 0 2.9 ± 0.3 2 ± 0 -11.7
3.2.05.02. Caulosegnin I 2lx6 Caulobacter segnis Secreted 1 0 2.9 ± 0.8 15 ± 5 -6.0
3.1.14.01. Eledoisin 1mxq Eledone cirrhosa (Curled octopus) Secreted 1 0 2.9 ± 1.7 59 ± 19 -5.0
3.1.02.02. S4-S5 linker peptide (532-551) of HERG K+ channel 2le7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.4 69 ± 9 -5.0
3.1.35.01. Cn-AMP1 peptide 2n0v Cocos nucifera Secreted 1 0 2.9 ± 1.3 73 ± 18 -2.3
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 2 3c6e Dengue virus Viral 1 0 2.9 ± 2.7 42 ± 5 -3.6
2.1.03.01. Alpha-toxin (PHLC1_CLOPE), open state 1ca1 Clostridium perfringens Secreted 1 0 2.9 ± 1.0 89 ± 4 -9.3
2.4.16.02. Nasonin 2koz Nasonia vitripennis (Parasitic wasp) Secreted 1 0 2.9 ± 0.9 68 ± 7 -4.6
2.2.34.02. Delta-amaurobitoxin-Pl1a 1v90 Pireneitega luctuosa (Tangled nest spider) Secreted 1 0 2.9 ± 0.7 26 ± 14 -4.0
3.2.06.01. Paralytic peptide 2 1v28 Manduca sexta Secreted 1 0 2.9 ± 1.4 90 ± 16 -4.9
2.2.11.01. Rabphilin-3A, C2A domain 2chd Rattus norvegicus Eukaryo. plasma 1 0 2.9 ± 1.6 57 ± 19 -2.7
1.2.19.01. Mitochondrial import receptor subunit TOM20, 51-145, with presequence peptide 1om2 Rattus norvegicus Mitochon. outer 2 0 2.9 ± 2.7 76 ± 7 -4.8
3.1.11.01. Neuropeptide F 1k8v Moniezia expansa (Sheep tapeworm) Secreted 1 0 2.9 ± 1.1 68 ± 9 -7.0
3.2.06.01. Growth-blocking peptide 2djc Spodoptera litura Secreted 1 0 2.9 ± 2.0 19 ± 14 -3.1
3.4.02.06. Epilancin 15X 1w9n Staphylococcus epidermidis Secreted 1 0 2.9 ± 1.0 72 ± 7 -5.0
1.2.04.01. Integrin alpha-IIb, cytoplasmic domain 1s4w Homo sapiens Eukaryo. plasma 1 0 2.9 ± 0.3 69 ± 3 -9.1
2.2.06.02. Fatty acid-binding protein homolog 1 1o8v Echinococcus granulosus Eukaryo. plasma 1 0 2.9 ± 1.0 48 ± 15 -5.8
2.2.06.02. Retinol-binding protein 2 2rcq Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 55 ± 6 -5.5
2.4.11.01. beta-Purothionin 1bhp Triticum aestivum Secreted 1 0 2.9 ± 2.0 56 ± 19 -4.8
2.2.07.01. Polyisoprenoid-binding protein 1wub Thermus thermophilus Bact. Gram-neg inner 1 0 2.9 ± 1.9 42 ± 13 -4.4
2.3.14.01. Yeast Sec14 Homolog Sfh1 (YKL091C) 3b7n Saccharomyces cerevisiae Nuclear outer 1 0 2.9 ± 1.5 65 ± 18 -5.8
2.1.29.05. Apolipoprotein C-III 2jq3 Homo sapiens Secreted 1 0 2.9 ± 1.4 85 ± 0 -5.6
2.2.21.02. Fibroblast growth factor 19 1pwa Homo sapiens Secreted 1 0 2.9 ± 1.5 48 ± 21 -4.7
2.2.35.01. Pneumolysin, structure 6 5aof Streptococcus pneumoniae Secreted 1 0 2.9 ± 2.4 33 ± 9 -5.7
2.4.33.01. 72 kDa type IV collagenase, full-length 1ck7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 73 ± 9 -4.0
2.4.51.01. Heme acquisition protein HasA, alternative position of heme 3mol Pseudomonas aeruginosa Secreted 1 0 2.9 ± 0.6 40 ± 5 -5.8
2.2.24.01. Vitelline membrane outer protein-I 1vmo Gallus gallus Secreted 1 0 3.0 ± 2.0 51 ± 12 -5.3
2.3.13.04. Glutathione peroxidase-like protein 2vup Trypanosoma brucei Undefined 1 0 3.0 ± 1.7 84 ± 7 -4.1
2.2.06.02. Intestinal fatty acid binding protein, structure 2 3akm Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.1 46 ± 8 -4.4
2.3.13.06. Chloride intracellular channel protein 1 1rk4 Homo sapiens Nuclear outer 1 0 3.0 ± 1.0 40 ± 5 -5.5
2.4.07.01. Sorting nexin-11, conformation 2 4ikd Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.2 58 ± 4 -5.3
1.2.50.01. Equinatoxin II 1iaz Actinia equina Secreted 1 0 3.0 ± 1.2 44 ± 9 -5.1
3.2.05.02. Microcin J25, redesigned, version 1 2mmt Designed proteins Undefined 1 0 3.0 ± 0.9 90 ± 5 -5.2
2.1.01.01. Myotoxin 1god Bothrops godmani Secreted 1 0 3.0 ± 0.8 80 ± 8 -7.4
2.3.18.01. Carnitine O-acetyltransferase, complex with substrate 2h3u Mus musculus Mitochon. inner 1 0 3.0 ± 1.0 87 ± 3 -5.9
2.4.16.13 Copsin 2mn5 Coprinopsis cinerea Secreted 1 0 3.0 ± 1.5 59 ± 9 -5.9
2.2.20.01. Pleckstrin homology domain-containing family A member 5 (PLEKHA5) 2dkp Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.9 64 ± 6 -3.9
3.1.13.01. Calcitonin 1bku Anguilla japonica (Japanese eel) Secreted 1 0 3.0 ± 0.4 77 ± 3 -8.7
2.2.11.01. Synaptotagmin-like protein 4 3fdw Homo sapiens Vesicle 1 0 3.0 ± 2.0 71 ± 17 -3.6
2.4.06.01. Steroidogenic acute regulatory protein, mitochondrial 3p0l Homo sapiens Mitochon. outer 1 0 3.0 ± 1.3 76 ± 10 -4.7
2.3.06.07. Tentative lipase 2zyr Archaeoglobus fulgidus Secreted 1 0 3.0 ± 1.0 57 ± 8 -7.5
2.1.02.01. Arachidonate 5-lipoxygenase, complex with arachidonic acid 3v99 Homo sapiens Eukaryo. plasma 1 0 3.0 ± 2.3 88 ± 9 -2.5
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 3ml9 Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.8 83 ± 2 -6.0
3.1.28.05. Aurein 1.2 analogue 2f3a Designed proteins Undefined 1 0 3.0 ± 1.6 88 ± 24 -11.7
3.4.02.01. Actagardine, structure in acetonitrile solution 1aj1 Actinoplanes liguriae Secreted 1 0 3.0 ± 1.1 90 ± 11 -5.7
1.2.18.01. Sortase B 1rz2 Bacillus anthracis Bact. Gram-pos plas. 1 0 3.0 ± 0.6 82 ± 6 -5.8
2.2.07.01. Acidic stress response factor 3hpe Helicobacter pylori Bact. Gram-neg inner 1 0 3.0 ± 0.7 34 ± 8 -6.1
2.4.31.01. Ficolin-1 2wnp Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.8 65 ± 2 -5.3
2.2.20.01. Rho guanine nucleotide exchange factor 9, conformation 2 4mt6 Rattus norvegicus Eukaryo. plasma 1 0 3.0 ± 1.9 68 ± 4 -5.1
2.1.35.01. Protein kinase C and casein kinase substrate 3qni Homo sapiens Eukaryo. plasma 2 0 3.0 ± 0.0 90 ± 0 -6.4
2.4.15.01. Protein Nef 1avv Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.0 ± 1.5 75 ± 13 -3.4
2.2.34.02. Jingzhaotoxin-11 2a2v Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.0 ± 1.8 74 ± 19 -4.6
2.2.20.01. Phosphoinositol 3-phosphate binding protein 1 1upr Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.4 62 ± 19 -3.6
2.2.11.01. Synaptotagmin-1 C2A-C2B domains 2r83 Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.9 89 ± 10 -3.8
2.1.15.02. Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) 1dvp Drosophila melanogaster Endosome 2 0 3.0 ± 0.0 89 ± 0 -6.6
2.4.34.01. Ice-structuring protein RD3 1c89 Lycodichthys dearborni Secreted 1 0 3.0 ± 1.0 85 ± 9 -8.7
2.1.02.01. Seed lipoxygenase-1 1yge Glycine max Eukaryo. plasma 1 0 3.0 ± 2.6 68 ± 3 -6.4
2.4.33.02. Collagenase 2y3u Clostridium histolyticum Secreted 1 0 3.0 ± 1.0 89 ± 4 -5.4
2.3.30.01. Aspartate carbamoyltransferase 5ilq Plasmodium falciparum Chloroplast outer 3 0 3.0 ± 0.4 88 ± 1 -7.2
2.1.01.01. Snake phospholipase A2, group I 1s6b Naja sagittifera Secreted 1 0 3.0 ± 1.1 81 ± 10 -7.5
1.2.38.01. Penicillin-binding protein 1A 2oqo Aquifex aeolicus Bact. Gram-neg inner 1 0 3.0 ± 1.0 40 ± 6 -11.0
2.3.02.03. Phospholipase D 3rlh Loxosceles intermedia Secreted 1 0 3.0 ± 0.7 81 ± 6 -6.2
3.1.20.01. Alpha-conotoxin OmIA 2gcz Conus omaria (Omaria cone) Secreted 1 0 3.0 ± 1.5 62 ± 11 -3.7
3.4.03.01. Heat-stable enterotoxin ST-IA/ST-P 1etn Escherichia coli Secreted 1 0 3.0 ± 3.7 33 ± 39 -2.1
2.3.18.01. Carnitine O-acetyltransferase 1ndb Mus musculus Mitochon. inner 1 0 3.0 ± 0.9 85 ± 6 -7.6
2.2.26.01. Early endosome antigen 1 (EEA1), monomer 1hyi Homo sapiens Endosome 1 0 3.0 ± 2.0 24 ± 17 -3.5
2.2.34.02. Omega-hexatoxin-Hv2a 1g9p Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 3.0 ± 1.4 78 ± 5 -4.0
1.2.55.01. Neutral ceramidase, structure 1 2zws Pseudomonas aeruginosa Secreted 1 0 3.1 ± 2.4 77 ± 3 -8.1
3.2.06.01. Plasmatocyte-spreading peptide PSP1 1b5n Pseudoplusia includens Secreted 1 0 3.1 ± 1.2 87 ± 16 -3.7
2.2.09.03. Surface layer protein 1l0q Methanosarcina mazei (Methanosarcina frisia) Archaebac. 1 0 3.1 ± 0.9 81 ± 7 -5.1
2.2.06.01. Allergen Bos d 2 1bj7 Bos taurus Secreted 1 0 3.1 ± 1.3 50 ± 6 -3.5
2.2.06.02. Cellular retinol-binding protein II 1kqw Danio rerio Eukaryo. plasma 1 0 3.1 ± 1.3 45 ± 13 -4.9
2.3.12.01. Myotubularin-related protein 2, monomer 1zvr Homo sapiens Endosome 1 0 3.1 ± 0.4 89 ± 8 -5.0
2.2.34.08. Agouti-related protein 1mr0 Homo sapiens Secreted 1 0 3.1 ± 2.0 37 ± 18 -5.6
1.2.53.01. Squalene synthase, conformation 1 3v66 Homo sapiens Endoplasm. reticulum 1 0 3.1 ± 0.8 83 ± 6 -5.1
2.2.11.01. Perforin-1 3nsj Mus musculus Vesicle 1 0 3.1 ± 1.0 34 ± 11 -3.3
2.3.06.12. Sulfolobus shibatae 3wj1 Sulfolobus shibatae Secreted 1 0 3.1 ± 0.7 52 ± 6 -6.3
2.4.35.01. 8R-Lipoxygenase, N-terminal domain 1u5u Plexaura homomalla Eukaryo. plasma 1 0 3.1 ± 0.3 72 ± 3 -10.4
1.2.39.03. Disintegrin and metalloproteinase domain-containing protein 10 2ao7 Bos taurus Golgi 1 0 3.1 ± 1.4 81 ± 6 -5.7
2.2.12.01. Ganglioside GM2 activator, apo-protein 2ag4 Homo sapiens Lysosome 1 0 3.1 ± 1.3 58 ± 12 -5.4
2.2.06.02. Brain fatty acid binding protein 1fdq Homo sapiens Eukaryo. plasma 1 0 3.1 ± 1.4 51 ± 15 -4.9
2.3.06.01. Butyryl cholinesterase 1p0i Homo sapiens Eukaryo. plasma 1 0 3.1 ± 0.8 43 ± 10 -6.4
2.2.34.03. Toxin Ado1 1lmr Agriosphodrus dohrni Secreted 1 0 3.1 ± 1.6 60 ± 19 -4.7
2.3.06.18. Tle1 effector of type VI lipase 4o5p Pseudomonas aeruginosa Secreted 1 0 3.1 ± 2.5 85 ± 8 -5.8
2.4.15.01. Protein Nef, complex with T-cell surface glycoprotein CD3 zeta chain 3ik5 Simian immunodeficiency virus Eukaryo. plasma 2 0 3.1 ± 0.5 78 ± 7 -4.5
2.4.16.03. Toxin I5a 1sis Buthus eupeus Secreted 1 0 3.1 ± 1.4 74 ± 16 -4.4
2.1.21.04. Matrix protein p19 1a6s Rous sarcoma virus Viral 1 0 3.1 ± 2.7 89 ± 14 -3.6
3.2.05.02. Lassomycin 2mai Lentzea kentuckyensis Secreted 1 0 3.1 ± 1.0 72 ± 9 -4.7
2.2.18.01. Subunit mu of AP-2 clatrin adaptor complex, open conformation 2xa7 Rattus norvegicus Vesicle 4 0 3.1 ± 2.2 84 ± 14 -5.9
2.4.06.01. StAR-related lipid transfer protein 13 2pso Homo sapiens Eukaryo. plasma 1 0 3.1 ± 4.0 77 ± 27 -4.6
2.2.11.01. Protein kinase C beta, C2 domain 1a25 Rattus norvegicus Eukaryo. plasma 1 0 3.1 ± 1.0 44 ± 18 -2.8
2.3.13.01. Glutathione transferase GST1-4 3g7j Anopheles dirus Undefined 2 0 3.1 ± 0.3 88 ± 1 -7.6
3.1.29.01. Fowlicidin-2 2gdl Gallus gallus Secreted 1 0 3.1 ± 0.5 85 ± 4 -8.9
1.1.73.01. TrbI protein 2bhv Helicobacter pylori Bact. Gram-neg outer 1 0 3.1 ± 1.3 42 ± 11 -6.4
1.2.47.01. Nickel-cobalt-cadmium resistance protein NccX 4clv Alcaligenes xylosoxidans Bact. Gram-neg inner 1 0 3.1 ± 0.9 83 ± 0 -6.7
2.1.18.01. Annexin V 1yii Gallus gallus Eukaryo. plasma 1 0 3.1 ± 0.7 79 ± 7 -5.1
3.1.29.01. Cathelicidin-3, peptide 121-151 2hfr Gallus gallus Secreted 1 0 3.1 ± 4.2 86 ± 1 -8.0
1.2.14.01. Transforming growth factor beta receptor type 3 3qw9 Rattus norvegicus Eukaryo. plasma 2 0 3.1 ± 0.3 87 ± 4 -9.9
2.4.21.02. L-alanyl-D-glutamate peptidase 2vo9 Listeria phage A500 Secreted 1 0 3.1 ± 1.0 48 ± 4 -5.2
2.3.10.03. LPS heptosyltransferase II, WaaF 1psw Escherichia coli Bact. Gram-neg inner 1 0 3.1 ± 1.1 58 ± 8 -5.6
2.3.06.05. Esterase 5dwd Pelagibacterium halotolerans Secreted 1 0 3.1 ± 2.1 66 ± 20 -4.7
2.1.01.01. Snake phospholipase A2, group I, isoform 1 1tc8 Bungarus caeruleus Secreted 1 0 3.1 ± 1.4 89 ± 11 -5.0
2.1.14.01. Peroxisomal targeting signal 1 receptor, complex with sterol carrier protein 2 2c0l Homo sapiens Peroxisome 2 0 3.1 ± 2.5 85 ± 35 -5.5
2.2.06.02. Der f 13 allergen 2a0a Dermatophagoides farinae (American house dust mite) Secreted 1 0 3.1 ± 1.3 50 ± 6 -3.5
2.4.16.04. Defensin-like protein 1 1gpt Hordeum vulgare Secreted 1 0 3.1 ± 1.6 28 ± 18 -2.0
2.2.41.01. Paneth cell-specific alpha-defensin 1 2mxq Equus caballus Secreted 1 0 3.1 ± 0.6 75 ± 5 -7.2
2.3.22.01. Uncharacterized protein 1rtt Pseudomonas aeruginosa Undefined 1 0 3.1 ± 2.5 70 ± 22 -4.1
2.3.06.01. Acetylcholinesterase 4ey4 Homo sapiens Eukaryo. plasma 1 0 3.2 ± 0.5 33 ± 2 -8.4
2.3.06.06. Lipase 4l3w Rhizopus chinensis Secreted 1 0 3.2 ± 0.7 31 ± 2 -6.5
1.1.09.01. Calcium ATPase, E1 state, with macrolide BLS 4ycm Oryctolagus cuniculus Endoplasm. reticulum 1 10 3.2 ± 1.8 21 ± 1 -66.3
2.4.34.01. Ice-structuring protein 4ur4 Zoarces viviparus Secreted 1 0 3.2 ± 4.1 68 ± 2 -5.8
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 3 4axc Arabidopsis thaliana Eukaryo. plasma 1 0 3.2 ± 2.3 68 ± 15 -4.5
2.2.34.02. Beta-theraphotoxin-Cj1a 2i1t Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 3.2 ± 0.7 58 ± 6 -5.8
3.1.21.04. Spiderine-1a 2n85 Oxyopes takobius (Lynx spider) Secreted 1 0 3.2 ± 4.2 88 ± 0 -7.8
2.1.51.01. Protein farnesyltransferase/geranylgeranyltransferase 1jcr Rattus norvegicus Eukaryo. plasma 2 0 3.2 ± 2.3 56 ± 5 -5.6
3.2.05.02. Astexin-1, structure 2 2m37 Asticcacaulis excentricus Secreted 1 0 3.2 ± 1.1 83 ± 13 -5.1
2.1.64.01. Envelope glycoprotein, ligand-binding domain 2 5fb7 Talaromyces marneffei Eukaryo. plasma 1 0 3.2 ± 2.5 64 ± 10 -2.9
2.3.09.01. Cytidylyltransferase, first membrane-anchoring helix 1peh Rattus norvegicus Eukaryo. plasma 1 0 3.2 ± 0.6 90 ± 2 -5.0
3.1.01.02. Leader peptide of bacteriocin microcin B17 2mlp Escherichia coli Secreted 1 0 3.2 ± 3.6 84 ± 4 -6.6
2.3.16.07. Ras-related C3 botulinum toxin substrate 1 2p2l Homo sapiens Eukaryo. plasma 1 0 3.2 ± 0.8 58 ± 2 -5.2
3.1.07.06. NS2 protease, segment 766-789 of polyprotein 2lzq Hepatitis GB virus Endoplasm. reticulum 1 0 3.2 ± 2.1 88 ± 1 -5.9
1.2.32.01. Cholesterol side-chain cleavage enzyme (P450 11A1) 3mzs Bos taurus Mitochon. inner 1 0 3.2 ± 0.3 33 ± 1 -6.7
2.3.02.01. Phospholipase C-beta isoform 3, complex with Galpha Q, structure 2 4qj3 Homo sapiens Eukaryo. plasma 2 0 3.2 ± 1.7 63 ± 10 -6.2
3.4.02.02. Mersacidin, crystal structure 1qow Bacillus sp. Secreted 3 0 3.2 ± 2.7 72 ± 31 -5.5
2.4.23.01. Methyl-accepting chemotaxis protein 3eee Thermoanaerobacter tengcongensis Undefined 1 0 3.2 ± 0.9 81 ± 4 -5.9
2.1.21.02. Matrix protein p10, myristoylated, structure 1 2lpy Mason-Pfizer monkey virus Viral 1 0 3.2 ± 0.5 8 ± 6 -3.4
3.1.28.06. Magainin analogue, MSI-594 2k98 Designed proteins Undefined 1 0 3.2 ± 0.2 86 ± 2 -8.9
2.3.06.03. Gastric lipase, closed state 1hlg Homo sapiens Secreted 1 0 3.2 ± 1.4 6 ± 12 -5.6
2.2.20.01. Triple functional domain protein 1nty Homo sapiens Eukaryo. plasma 1 0 3.2 ± 2.0 59 ± 16 -3.9
3.1.05.07. Penetratin 1omq Designed proteins Undefined 1 0 3.2 ± 1.0 79 ± 7 -7.4
3.1.07.02. Peptide of envelope glycoprotein H (625-644) 2lqy Human herpesvirus Endosome 1 0 3.2 ± 0.8 88 ± 5 -10.2
2.4.20.01. Cysteine protease 3ois Xylella fastidiosa Undefined 1 0 3.2 ± 0.2 80 ± 4 -6.4
2.3.19.01. Toxin A 4r04 Clostridium difficile Secreted 1 0 3.2 ± 2.4 74 ± 2 -6.7
3.1.18.01. Delta-hemolysin 1dtc Staphylococcus aureus Secreted 1 0 3.2 ± 2.2 87 ± 19 -8.5
1.2.03.02. T-cell immunoglobulin and mucin domain-containing protein 4 3bib Mus musculus Eukaryo. plasma 1 0 3.2 ± 1.9 41 ± 7 -4.6
2.1.25.03. Enterocin 7B 2m60 Enterococcus faecalis Secreted 1 0 3.2 ± 1.6 53 ± 15 -3.8
2.2.20.01. PH domain of Src-associated adaptor protein 2 1u5e Mus musculus Eukaryo. plasma 2 0 3.2 ± 2.0 39 ± 13 -4.6
2.3.19.01. Alpha-toxin 2vk9 Clostridium novyi Secreted 1 0 3.2 ± 1.0 80 ± 2 -5.2
2.2.12.01. Ganglioside GM2 activator 2agc Mus musculus Lysosome 1 0 3.2 ± 1.0 54 ± 12 -5.3
2.2.35.01. Listeriolysin O 4cdb Listeria monocytogenes Secreted 1 0 3.2 ± 0.0 30 ± 0 -6.0
2.1.15.01. Epsin-1 1h0a Rattus norvegicus Eukaryo. plasma 1 0 3.2 ± 1.1 39 ± 19 -5.3
1.2.43.05. Major envelope glycoprotein 3duz Autographa californica nuclear polyhedrosis virus Viral 3 0 3.2 ± 0.4 4 ± 6 -9.3
1.3.24.01. Cation efflux system protein CusC, monomer 4k7k