PDB ID or protein name

All proteins in OPM (3809 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.4.07.01. Sorting nexin-5 3hpc Rattus norvegicus Endosome 1 0 0.0 ± 2.1 90 ± 8 -2.4
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2 2w8d Bacillus subtilis Bact. Gram-pos plas. 1 0 0.0 ± 6.0 83 ± 58 -1.6
2.2.06.02. Fatty acid-binding protein 2k62 Gallus gallus Eukaryo. plasma 1 0 0.0 ± 2.9 82 ± 13 -2.0
1.1.116.01. Glycerol-3-phosphate acyltransferase, structure 5 5xj9 Aquifex aeolicus Bact. Gram-neg inner 1 7 0.0 ± 0.0 0 ± 0 0.0
1.2.38.03. Endo-type membrane-bound lytic murein transglycosylase A 2y8p Escherichia coli Bact. Gram-neg outer 1 0 0.0 ± 3.6 86 ± 15 -2.2
2.2.06.01. Prostaglandin-H2 D-isomerase 2ktd Mus musculus Endoplasm. reticulum 1 0 0.0 ± 1.4 73 ± 14 -2.2
1.2.53.01. Squalene synthase, conformation 4 3wek Homo sapiens Endoplasm. reticulum 1 0 0.4 ± 2.5 87 ± 15 -3.2
1.1.56.01. Glycerol phosphate lipoteichoic acid synthase 2w5q Staphylococcus aureus Bact. Gram-pos plas. 1 0 0.4 ± 3.6 82 ± 11 -2.5
2.1.01.01. Phospholipase A2, group IB 3elo Homo sapiens Secreted 1 0 0.4 ± 1.5 52 ± 16 -3.5
2.4.05.01. Uncharacterized protein 3bkr Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.4 ± 6.2 50 ± 73 -1.2
2.1.11.01. Alpha-actinin-2 1hci Homo sapiens Eukaryo. plasma 2 0 0.4 ± 0.7 90 ± 12 -5.1
3.2.01.05. Protegrin-3, dimer 2mz6 Sus scrofa Secreted 2 0 0.4 ± 2.1 89 ± 2 -2.3
2.1.08.01. Cytochrome c6 1c6s Thermosynechococcus elongatus Thylakoid 1 0 0.4 ± 1.7 89 ± 16 -1.3
2.4.13.01. Protein Osh1 5h2d Kluyveromyces lactis Vacuole 1 0 0.4 ± 2.4 71 ± 26 -2.7
3.2.01.04. Symmetrical θ-defensin, BTD-2 2lye Macaca mulatta Secreted 1 0 0.4 ± 2.9 80 ± 22 -1.5
3.2.01.03. Gomesin 1kfp Acanthoscurria gomesiana (Tarantula spider) Secreted 1 0 0.5 ± 1.0 75 ± 6 -2.7
2.2.20.01. Cytohesin-2 1u27 Mus musculus Eukaryo. plasma 1 0 0.5 ± 2.4 53 ± 9 -2.4
2.2.06.01. Beta-lactoglobulin 3nq9 Bos taurus Secreted 1 0 0.5 ± 0.9 89 ± 4 -2.7
2.1.29.03. Apolipoprotein C-I, peptide 27-83 1ioj Homo sapiens Secreted 1 0 0.6 ± 1.8 80 ± 16 -2.8
2.2.20.01. Pleckstrin homology domain-containing family B member 2 2dhi Mus musculus Eukaryo. plasma 1 0 0.6 ± 1.5 86 ± 14 -2.8
2.2.34.02. Hybrid atracotoxin 2h1z Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 0.6 ± 2.0 82 ± 20 -1.9
2.2.06.02. Fatty acid-binding protein 2 2ftb Ambystoma mexicanum (Axolotl) Eukaryo. plasma 1 0 0.6 ± 2.0 77 ± 20 -1.7
1.2.04.01. Integrin beta-3, 742-788, 747pY, in water 2ljf Homo sapiens Eukaryo. plasma 1 0 0.6 ± 1.6 62 ± 14 -1.8
2.1.60.02. Lasiocepsin 2mbd Lasioglossum laticeps Secreted 1 0 0.6 ± 1.3 47 ± 15 -2.5
2.1.42.01. PapB 2ip6 Pediococcus pentosaceus Secreted 1 0 0.6 ± 2.6 72 ± 23 -2.2
3.4.10.01. Methanobactin 2xjh Methylosinus trichosporium Secreted 1 0 0.7 ± 0.7 67 ± 7 -2.9
2.3.25.02. Lipolytic protein 4rw0 Veillonella parvula Secreted 1 0 0.7 ± 0.7 60 ± 5 -4.0
2.2.15.01. Gamma-crystallin F 1m8u Bos taurus Secreted 1 0 0.7 ± 1.2 85 ± 4 -4.9
2.2.06.02. Prostaglandin-H2 D-isomerase, ligand-bound 3o22 Homo sapiens Endoplasm. reticulum 1 0 0.7 ± 1.2 78 ± 13 -2.4
2.3.16.06. ADP-ribosylation factor-like protein 1 1moz Saccharomyces cerevisiae Golgi 2 0 0.7 ± 1.1 90 ± 6 -4.3
2.1.60.03. Cysteine-rich secretory protein 2 2cq7 Homo sapiens Secreted 1 0 0.7 ± 1.1 68 ± 5 -2.5
2.2.34.02. Omega-theraphotoxin-Hh1a 1y29 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 0.7 ± 1.3 83 ± 17 -2.7
2.2.26.01. RUN and FYVE domain-containing protein 1 2yw8 Homo sapiens Endosome 1 0 0.7 ± 3.4 48 ± 38 -2.8
2.1.19.01. Kappa-buthitoxin-Tt2b 2li3 Tityus trivittatus Secreted 1 0 0.8 ± 0.7 40 ± 6 -2.7
2.1.25.05. Aureocin A53 2n8o Staphylococcus aureus Secreted 1 0 0.8 ± 0.4 78 ± 6 -2.6
2.1.21.02. Matrix protein p10, myristoylated, structure 4 2mv4 Mason-Pfizer monkey virus Viral 1 0 0.8 ± 0.8 46 ± 6 -3.0
2.4.16.01. Alpha-insect toxin Lqq3 1lqq Leiurus quinquestriatus quinquestriatus Secreted 1 0 0.8 ± 1.0 80 ± 6 -3.3
3.2.01.04. Theta-defensin 1 (RTD-1) 1hvz Macaca mulatta Secreted 1 0 0.8 ± 1.0 89 ± 4 -2.9
3.2.01.03. Toxin AbTx 2m6j Sparassidae Secreted 1 0 0.8 ± 3.6 89 ± 6 -3.0
2.2.20.01. Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 3nsu Saccharomyces cerevisiae Eukaryo. plasma 1 0 0.8 ± 1.5 57 ± 12 -4.0
2.4.05.01. Sterol carrier protein 2 1pz4 Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.8 ± 5.0 37 ± 49 -1.3
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3b 5kar Mus musculus Secreted 1 0 0.8 ± 1.3 51 ± 4 -3.9
3.1.20.01. Alpha-conotoxin CnIA 1b45 Conus consors (Singed cone) Secreted 1 0 0.8 ± 0.8 80 ± 20 -2.1
2.2.11.01. Protein kinase C alpha, complex with phosphatidyl serine 1dsy Rattus norvegicus Eukaryo. plasma 1 0 0.9 ± 1.5 18 ± 16 -3.0
2.3.06.11. Monoglyceride lipase MGLL, closed conformation 3pe6 Homo sapiens Eukaryo. plasma 1 0 0.9 ± 3.0 54 ± 28 -2.7
2.2.41.01. Oral alpha defensin 1 2k1i Macaca mulatta Secreted 1 0 0.9 ± 3.2 70 ± 15 -2.2
1.2.50.02. Nakanori protein 5h0q Grifola frondosa Eukaryo. plasma 1 0 0.9 ± 1.8 37 ± 15 -3.1
3.4.13.01. T-cell-specific surface glycoprotein CD28, intracellular loop 2nae Mus musculus Eukaryo. plasma 1 0 0.9 ± 10.0 81 ± 3 -6.4
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 2 1zhy Saccharomyces cerevisiae Golgi 1 0 0.9 ± 0.4 87 ± 4 -4.7
1.2.03.02. T-cell immunoglobulin and mucin domain-containing protein 2 2or7 Mus musculus Eukaryo. plasma 1 0 0.9 ± 0.7 54 ± 6 -3.3
3.2.01.07. Peptidomimetic TWLKKRRWKKAK-D-Pro-P 2m7j Designed proteins Undefined 1 0 1.0 ± 1.7 75 ± 37 -2.7
2.1.41.01. Phosphatidylinositol 4-kinase type 2-alpha, structure 2 4pla Homo sapiens Golgi 1 0 1.0 ± 1.7 49 ± 3 -2.8
3.1.02.09. Peptide (659-711) of platelet endothelial cell adhesion molecule 2ky5 Homo sapiens Eukaryo. plasma 1 0 1.0 ± 3.8 89 ± 3 -3.7
2.2.05.01. Azurin I 1rkr Alcaligenes xylosoxidans Bact. Gram-neg inner 1 0 1.0 ± 1.0 43 ± 7 -4.3
2.2.33.01. Hevein 1q9b Hevea brasiliensis (Para rubber tree) Secreted 1 0 1.0 ± 1.0 90 ± 11 -1.8
2.2.07.01. YceI-like protein 3q34 Pseudomonas syringae Bact. Gram-neg inner 2 0 1.0 ± 1.1 89 ± 2 -3.9
2.2.34.01. Conotoxin mr3e 2efz Conus marmoreus Secreted 1 0 1.0 ± 1.3 83 ± 25 -3.2
2.4.05.01. Sterol carrier protein 2-like 2 2qzt Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 1.0 ± 2.0 45 ± 12 -3.0
2.3.13.02. Phosducin/Transducin beta-gamma complex, conformation 3 1b9x Rattus norvegicus Eukaryo. plasma 3 0 1.0 ± 1.6 49 ± 12 -3.9
2.1.21.05. Matrix protein p15 1hek Equine infectious anemia virus Endosome 1 0 1.0 ± 2.8 76 ± 21 -2.6
2.3.06.19. PHB depolymerase PhaZ7, structure 2 4btv Pseudomonas lemoignei Secreted 1 0 1.0 ± 2.3 64 ± 35 -5.2
2.3.08.02. Cytosolic phospholipase A2 delta, structure 2 5iz5 Homo sapiens Vesicle 1 0 1.0 ± 0.0 77 ± 0 -4.1
1.2.32.01. Cytochrome P450 17A2 4r21 Danio rerio Endoplasm. reticulum 1 0 1.0 ± 10.0 70 ± 10 -2.4
2.2.20.01. Pleckstrin homology domain-containing family A member 6 (PLEKHA6) 2d9y Homo sapiens Eukaryo. plasma 1 0 1.0 ± 0.3 67 ± 1 -6.2
2.1.26.01. Colicin-E1 2i88 Escherichia coli Secreted 1 0 1.1 ± 3.3 58 ± 37 -1.7
2.2.06.02. Fatty acid binding protein 6, ileal (Gastrotropin) 3elz Danio rerio Eukaryo. plasma 1 0 1.1 ± 0.9 85 ± 6 -2.4
1.1.56.01. Inner membrane protein YejM, strain K12 5i5h Salmonella typhimurium Bact. Gram-neg inner 1 0 1.1 ± 1.6 65 ± 2 -3.6
2.4.16.03. Charybdotoxin 2crd Leiurus quinquestriatus hebraeus Secreted 1 0 1.1 ± 1.5 86 ± 15 -3.2
2.2.34.01. Omega-conotoxin SVIB 1mvj Conus striatus Secreted 1 0 1.1 ± 2.1 20 ± 24 -2.1
2.2.12.02. Rho GDP-dissociation inhibitor 1, complex with cell division control protein 42 1doa Homo sapiens Eukaryo. plasma 2 0 1.1 ± 1.3 87 ± 4 -3.1
3.1.29.01. Cathelin-related peptide SC5 (SMAP-29) 1fry Ovis aries Secreted 1 0 1.1 ± 0.8 18 ± 9 -3.5
2.4.16.02. Lucifensin 2lld Lucilia sericata Secreted 1 0 1.1 ± 1.7 11 ± 12 -3.0
2.2.06.01. Allergen Per a 4 3ebw Periplaneta americana Secreted 1 0 1.1 ± 1.1 69 ± 28 -3.9
2.1.10.01. Glycolipid transfer protein, structure 2 1wbe Bos taurus Eukaryo. plasma 1 0 1.1 ± 2.4 89 ± 8 -9.4
3.1.11.01. Pancreatic hormone 1v1d Bos taurus Secreted 1 0 1.2 ± 3.0 79 ± 32 -1.9
2.1.60.01. Potassium channel toxin ShK 1roo Stoichactis helianthus Secreted 1 0 1.2 ± 1.2 46 ± 8 -3.7
2.4.16.02. Navitoxin 2rty Nasonia vitripennis (Parasitic wasp) Secreted 1 0 1.2 ± 3.4 90 ± 17 -3.9
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 1 1zhx Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.9 90 ± 7 -5.0
2.3.16.06. ADP-ribosylation factor-like protein 8A 2h18 Homo sapiens Endosome 1 0 1.2 ± 3.6 58 ± 28 -2.6
2.4.16.04. Defensin-like protein 1brz Pentadiplandra brazzeana Secreted 1 0 1.2 ± 1.2 83 ± 10 -3.6
2.2.12.01. Mite group 2 allergen Der f 2 1xwv Dermatophagoides farinae (American house dust mite) Secreted 1 0 1.2 ± 1.4 64 ± 10 -3.1
2.4.07.01. PX domain of serine/threonine-protein kinase Sgk3 1xte Homo sapiens Endosome 1 0 1.2 ± 1.4 77 ± 11 -2.9
1.2.32.01. Fatty-acid peroxygenase 1izo Bacillus subtilis Bact. Gram-pos plas. 1 0 1.2 ± 0.3 76 ± 1 -5.5
2.2.06.02. Fatty acid-binding protein 2flj Locusta migratoria (Migratory locust) Eukaryo. plasma 1 0 1.2 ± 1.5 62 ± 10 -3.6
2.3.14.01. Retinaldehyde-binding protein 1, closed state 3hx3 Homo sapiens Eukaryo. plasma 1 0 1.2 ± 2.9 77 ± 32 -4.8
1.2.29.01. Septation ring formation regulator EzrA 4uy3 Staphylococcus aureus Bact. Gram-pos plas. 1 0 1.2 ± 2.8 44 ± 4 -3.0
2.4.11.01. Viscotoxin B 1jmp Viscum album Secreted 1 0 1.2 ± 1.4 52 ± 13 -3.2
2.1.24.01. Saposin B (peptide 195-273), structure 1 1n69 Homo sapiens Lysosome 2 0 1.2 ± 1.0 58 ± 6 -2.4
2.1.01.01. Phospholipase A2 homolog 1ppa Agkistridon piscivorus Secreted 1 0 1.2 ± 0.9 85 ± 8 -4.5
3.1.22.01. Antifungal peptide 2mp9 Cenchritis muricatus Secreted 1 0 1.2 ± 1.5 90 ± 26 -3.7
2.1.19.01. Antimicrobial peptide Tk-Amp-X2 2m6a Hordeum vulgare Secreted 1 0 1.2 ± 1.0 65 ± 7 -3.4
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 3 4jch Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.2 88 ± 1 -6.0
2.4.16.09. S-locus pollen protein 1ugl Brassica campestris (Field mustard) Secreted 1 0 1.3 ± 0.6 51 ± 5 -3.4
2.2.20.01. PH domain containing retinal protein 1 2d9v Mus musculus Eukaryo. plasma 1 0 1.3 ± 1.3 58 ± 14 -5.1
2.3.11.01. Ferrochelatase, conformation 2 (with porphyrin bound) 4klr Homo sapiens Mitochon. inner 2 0 1.3 ± 0.0 90 ± 1 -8.4
2.1.19.01. Ribosome-inactivating protein luffin P1 2l37 Luffa aegyptiaca Secreted 1 0 1.3 ± 0.9 80 ± 7 -3.3
2.2.06.02. Myelin P2 protein 1yiv Equus caballus Eukaryo. plasma 1 0 1.3 ± 1.7 53 ± 11 -4.8
2.2.05.01. Plastocyanin 2plt Chlamydomonas reinhardtii Thylakoid 1 0 1.3 ± 1.5 21 ± 18 -2.0
3.1.24.01. Penaeidin-3a 1ueo Litopenaeus vannamei (Whiteleg shrimp) Secreted 1 0 1.3 ± 3.5 89 ± 2 -5.5
2.4.16.07. Diapause-specific peptide 2e2f Gastrophysa atrocyanea (Leaf beetle) Secreted 1 0 1.3 ± 1.0 30 ± 10 -4.2
2.2.34.02. Mu-agatoxin-Aa1a 1eit Agelenopsis aperta Secreted 1 0 1.3 ± 1.5 59 ± 10 -3.1
2.4.19.01. Protein CutA 1osc Rattus norvegicus Eukaryo. plasma 3 0 1.3 ± 0.3 90 ± 1 -5.5
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform 3hhm Homo sapiens Eukaryo. plasma 2 0 1.3 ± 0.5 78 ± 1 -5.5
2.3.29.01. Undecaprenyl pyrophosphate synthase 2d2r Helicobacter pylori Bact. Gram-neg inner 2 0 1.3 ± 0.9 78 ± 1 -4.5
3.2.01.05. Cys-free protegrin analogue 2mq2 Designed proteins Secreted 1 0 1.3 ± 1.1 61 ± 19 -3.5
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 1 4b2z Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.3 ± 1.3 86 ± 6 -4.6
1.3.25.01. Gamma-hemolysin prepore, hetero-octamer (A+B) 4p1y Staphylococcus aureus Secreted 8 0 1.3 ± 1.0 85 ± 2 -7.8
3.1.20.01. Alpha-conotoxin GID 1mtq Conus geographus (Geography cone) Secreted 1 0 1.3 ± 2.5 78 ± 28 -2.4
2.2.41.01. Neutrophil defensin 3 1dfn Homo sapiens Secreted 2 0 1.4 ± 1.3 87 ± 15 -3.9
2.3.19.01. Cytotoxin L 2vkh Clostridium sordellii Secreted 1 0 1.4 ± 2.0 51 ± 17 -4.5
2.2.07.01. Lipocalin BcnA 5ixh Burkholderia cepacia Bact. Gram-neg inner 1 0 1.4 ± 2.6 28 ± 29 -1.7
2.2.20.01. Oxysterol binding protein-related protein 11 2d9x Homo sapiens Eukaryo. plasma 1 0 1.4 ± 1.7 55 ± 18 -3.1
2.3.25.02. Phospholipase A1 4hyq Streptomyces albidoflavus Secreted 1 0 1.4 ± 1.4 31 ± 7 -3.9
2.2.11.01. Phosphatidylinositide 3-kinase C2 alpha 2b3r Mus musculus Eukaryo. plasma 2 0 1.4 ± 1.5 88 ± 16 -4.4
2.3.12.01. Myotubularin-related protein 2, dimer 1m7r Homo sapiens Eukaryo. plasma 2 0 1.4 ± 0.3 89 ± 0 -6.4
2.3.23.01. Beta-Ketoacyl synthase/Acyl transferase 1tqy Streptomyces coelicolor Bact. Gram-pos plas. 2 0 1.4 ± 0.2 83 ± 1 -4.9
2.2.05.01. Azurin iso-2 1cuo Methylomonas sp. Bact. Gram-neg inner 1 0 1.4 ± 1.6 69 ± 15 -4.3
2.1.08.01. Cytochrome c2 1co6 Rhodopseudomonas viridis Bact. Gram-neg inner 1 0 1.4 ± 0.7 78 ± 10 -3.3
3.1.05.03. LAK160-P7 2l96 Designed proteins Undefined 1 0 1.4 ± 0.9 88 ± 5 -2.7
2.4.06.01. START and PH domains of collagen type IV alpha-3-binding protein 5jjd Homo sapiens Golgi 1 0 1.4 ± 2.6 48 ± 16 -4.4
2.2.05.01. Plantacyanin 1f56 Spinacia oleracea Thylakoid 1 0 1.4 ± 1.5 11 ± 15 -2.0
2.2.12.01. Mite group 2 allergen Der p 2 1ktj Dermatophagoides pteronyssinussearch Secreted 1 0 1.4 ± 1.3 65 ± 9 -3.2
2.3.06.05. Copper inducible hydrolase YahD 3og9 Lactococcus lactis Bact. Gram-pos plas. 1 0 1.4 ± 1.1 33 ± 10 -4.0
2.1.28.01. Heat-stable enterotoxin II 1ehs Escherichia coli Secreted 1 0 1.4 ± 1.1 64 ± 11 -6.0
2.2.11.01. Synaptotagmin-1, C2A domain (Calcium free) 3f00 Homo sapiens Eukaryo. plasma 1 0 1.4 ± 1.5 29 ± 18 -3.3
2.1.08.01. Cytochrome c551 451c Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 1.4 ± 0.9 85 ± 10 -5.4
2.1.60.03. Cysteine-rich secretory protein 2 2a05 Mus musculus Secreted 1 0 1.4 ± 1.8 52 ± 133 -2.8
2.2.58.01. Cone arrestin 1suj Ambystoma tigrinum (Tiger salamander) Eukaryo. plasma 1 0 1.4 ± 0.8 82 ± 12 -4.7
2.2.14.01. Retinoschisin 3jd6 Homo sapiens Eukaryo. plasma 8 0 1.4 ± 0.1 90 ± 0 -19.5
1.2.53.01. Squalene synthase, conformation 3 3weh Homo sapiens Endoplasm. reticulum 1 0 1.4 ± 2.5 90 ± 26 -3.8
2.2.20.01. PH domain of TAPP2 1v5p Mus musculus Eukaryo. plasma 1 0 1.4 ± 1.3 61 ± 5 -3.7
2.2.27.01. Ras association domain-containing protein 5, C1 domain 1rfh Mus musculus Eukaryo. plasma 1 0 1.4 ± 0.9 16 ± 6 -3.7
3.2.01.03. Androctonin 1cz6 Androctonus australis (Sahara scorpion) Secreted 1 0 1.5 ± 2.8 89 ± 16 -3.2
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 2 5iqw Pseudomonas aeruginosa Secreted 1 0 1.5 ± 0.2 24 ± 5 -4.8
2.1.18.01. Annexin GH1 1n00 Gossypium hirsutum Eukaryo. plasma 1 0 1.5 ± 2.0 70 ± 17 -3.7
2.1.24.01. Pore-forming peptide ameobapore A 1of9 Entamoeba histolytica Undefined 1 0 1.5 ± 1.0 13 ± 18 -2.3
2.3.16.06. ADP-ribosylation factor-like protein 5A 1z6y Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.9 66 ± 15 -4.0
2.2.20.01. RAC-gamma serine/threonine-protein kinase 2x18 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.1 53 ± 4 -3.8
2.2.33.01. Antimicrobial Peptide AMP-1.1a 2kus Stellaria media Secreted 1 0 1.5 ± 0.9 18 ± 27 -2.7
2.2.20.01. Myosin X 3tfm Rattus norvegicus Endosome 1 0 1.5 ± 2.6 81 ± 5 -3.0
2.1.21.03. Matrix protein p15 1mn8 Moloney murine leukemia virus Endosome 1 0 1.5 ± 1.8 65 ± 24 -3.5
2.4.42.01. Bactericidal permeability-increasing protein 1bp1 Homo sapiens Secreted 1 0 1.5 ± 2.4 51 ± 17 -4.3
2.2.32.01. ADP-ribosylating toxin CARDS, full-length 4tlw Mycoplasma pneumoniae Secreted 1 0 1.5 ± 1.4 47 ± 2 -4.8
2.2.26.01. LM-5 FYVE domain 1z2q Leishmania major Endosome 1 0 1.5 ± 1.5 22 ± 19 -3.4
2.2.11.01. Rab3 interacting molecule 2 (RIM2), C2A domain 2bwq Rattus norvegicus Eukaryo. plasma 1 0 1.5 ± 1.6 41 ± 19 -1.8
2.4.16.03. Potassium channel toxin alpha-KTx 6.9 6avd Opistophthalmus carinatus Secreted 1 0 1.5 ± 1.6 57 ± 7 -2.9
2.3.06.12. Heroin esterase 1lzk Rhodococcus sp. Bact. Gram-pos plas. 1 0 1.5 ± 1.5 69 ± 9 -4.0
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 2 4axd Arabidopsis thaliana Eukaryo. plasma 1 0 1.5 ± 0.1 88 ± 4 -4.0
2.1.24.01. Saposin B (peptide 195-273), structure 2 4v2o Homo sapiens Lysosome 2 0 1.5 ± 1.0 51 ± 4 -3.2
2.3.01.08. Endoglucanase H 2vi0 Clostridium thermocellum Bact. Gram-pos plas. 1 0 1.5 ± 1.3 36 ± 9 -3.8
2.2.41.01. Reptilian defensin 2b5b Caretta caretta Secreted 1 0 1.5 ± 0.4 73 ± 1 -4.1
2.3.18.01. Choline O-acetyltransferase 2fy2 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 2.2 87 ± 17 -5.2
1.2.03.08. HLA class II histocompatibility antigen, DM alpha chain 2bc4 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 0.7 21 ± 3 -4.7
1.1.107.01. Lysosome membrane protein 2 5uph Homo sapiens Lysosome 1 0 1.5 ± 1.5 82 ± 10 -3.4
2.1.58.01. Serine/threonine-protein kinase pelle 1ik7 Drosophila melanogaster Eukaryo. plasma 1 0 1.5 ± 3.7 86 ± 0 -6.8
2.4.16.02. Defensin MGD-1 1fjn Mytilus galloprovincialis (Mediterranean mussel) Secreted 1 0 1.5 ± 1.4 43 ± 12 -3.0
2.2.11.01. Multiple C2 and transmembrane domain-containing protein 2 (MCTP2) 2ep6 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.5 7 ± 15 -3.0
2.2.05.01. Pseudoazurin 1pmy Methylobacterium extorquens Bact. Gram-neg inner 1 0 1.6 ± 1.4 45 ± 13 -4.3
1.2.26.01. Outer membrane lipoprotein Wza, water-soluble part 2w8h Escherichia coli Bact. Gram-neg outer 8 0 1.6 ± 0.2 1 ± 0 -22.1
1.3.25.01. Necrotic enteritis toxin B 4i0n Clostridium perfringens Secreted 1 0 1.6 ± 2.4 38 ± 7 -4.3
2.3.14.01. Neurofibromin 2d4q Homo sapiens Eukaryo. plasma 1 0 1.6 ± 2.0 34 ± 19 -3.3
2.3.16.06. ADP-ribosylation factor-like protein 1 2x77 Leishmania major Eukaryo. plasma 1 0 1.6 ± 1.4 80 ± 5 -3.6
2.2.11.01. Synaptotagmin 1, C2B domain 5vfg Mus musculus Vesicle 1 0 1.6 ± 2.0 38 ± 11 -3.6
2.1.42.01. Mundticin KS immunity protein 2zrr Enterococcus mundtii Secreted 1 0 1.6 ± 1.5 72 ± 9 -3.2
3.1.21.01. Cecropin-P1 2n92 Ascaris suum Secreted 1 0 1.6 ± 3.4 90 ± 0 -4.1
2.3.25.01. Acyloxyacyl hydrolase, structure 2 5w7d Mus musculus Secreted 1 0 1.6 ± 0.8 82 ± 12 -3.6
2.4.37.01. Monalysin 4mjt Pseudomonas entomophila Secreted 9 0 1.6 ± 0.0 90 ± 0 -13.5
2.2.11.01. Synaptotagmin-1, C2B domain (Calcium-bound) 4v11 Homo sapiens Eukaryo. plasma 1 0 1.6 ± 2.3 40 ± 7 -3.2
2.1.42.01. Bacteriocin 2fu2 Streptococcus pyogenes Secreted 1 0 1.6 ± 1.1 77 ± 16 -3.7
2.2.41.04. Antimicrobial peptide LCI 2b9k Bacillus subtilis Secreted 1 0 1.6 ± 2.9 89 ± 19 -4.4
3.1.20.01. Alpha-conotoxin GIA 1not Conus geographus (Geography cone) Secreted 1 0 1.6 ± 1.5 89 ± 20 -2.3
2.1.29.01. Apolipoprotein E 1ya9 Mus musculus Secreted 1 0 1.6 ± 1.4 85 ± 11 -4.1
2.3.01.03. Alpha-amylase A 1wza Halothermothrix orenii Secreted 1 0 1.6 ± 0.4 80 ± 1 -6.7
2.2.20.01. PH-like domain of Lam6 5yqr Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.6 ± 1.6 83 ± 6 -4.5
3.2.01.01. Alvinellacin 2llr Alvinella pompejana Secreted 1 0 1.6 ± 1.4 90 ± 5 -2.6
3.1.20.01. O2-contryphan-Vc1 2n24 Conus victoriae (Queen Victoria cone) Secreted 1 0 1.6 ± 1.0 89 ± 22 -3.6
2.2.33.01. Antimicrobial peptide 2 1mmc Amaranthus caudatus (Inca-wheat) Secreted 1 0 1.6 ± 1.2 46 ± 9 -3.9
2.2.02.03. Flavivirin protease NS2B 2wv9 Murray valley encephalitis virus Endoplasm. reticulum 1 0 1.6 ± 2.4 69 ± 8 -4.7
2.1.21.02. Matrix protein p10, myristoylated, structure 3 5lmy Mason-Pfizer monkey virus Viral 1 0 1.6 ± 1.6 60 ± 5 -4.2
1.1.55.01. Bacterial polysaccharide co-polymerase FepE 3b8n Escherichia coli Bact. Gram-neg inner 9 0 1.6 ± 0.1 1 ± 0 -20.3
2.4.16.01. Alpha-mammal toxin AaH2 1aho Androctonus australis (Sahara scorpion) Secreted 1 0 1.7 ± 1.0 64 ± 17 -3.4
3.1.11.02. Extendin-4 1jrj Heloderma suspectum Secreted 1 0 1.7 ± 0.8 79 ± 8 -5.0
2.2.20.01. Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 2da0 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 2.5 64 ± 20 -2.5
2.1.02.01. Seed lipoxygenase-B 2iuj Glycine max Eukaryo. plasma 1 0 1.7 ± 3.0 51 ± 15 -4.8
2.1.29.01. Apolipoprotein A-I, alternative structure of C-terminal domain 3r2p Homo sapiens Secreted 2 0 1.7 ± 1.6 87 ± 3 -4.1
2.3.06.05. Carboxylesterase 2 1auo Pseudomonas fluorescens Bact. Gram-neg inner 1 0 1.7 ± 3.0 33 ± 21 -3.4
2.2.34.02. Kappa-hexatoxin-Hv1c 1dl0 Hadronyche versuta (Blue mountains funnel-web spider) Secreted 1 0 1.7 ± 1.3 53 ± 17 -3.1
2.2.20.01. PH domain of TAPP1 1eaz Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.6 87 ± 14 -3.0
2.2.17.01. 6.5 kDa glycine-rich antifreeze protein 2pne Hypogastrura harveyi Secreted 1 0 1.7 ± 0.2 89 ± 5 -7.7
2.2.11.01. Synaptotagmin-1, C2B domain (Calcium bound) 1uov Rattus norvegicus Eukaryo. plasma 1 0 1.7 ± 1.8 36 ± 13 -3.7
2.3.16.07. Ras-related protein Rab-7a 1vg8 Rattus norvegicus Endosome 1 0 1.7 ± 0.5 74 ± 3 -5.3
3.2.05.02. Sphingopyxin I 5jqf Sphingopyxis alaskensis Undefined 1 0 1.7 ± 1.8 40 ± 16 -3.7
2.3.21.01. Protein-tyrosine phosphatase, mitochondrial 1 3rgq Mus musculus Mitochon. inner 1 0 1.7 ± 0.7 54 ± 7 -4.9
2.2.11.01. Rabphilin-3A 2k3h Mus musculus Eukaryo. plasma 1 0 1.7 ± 2.1 78 ± 16 -4.1
1.2.03.04. Leukocyte immunoglobulin-like receptor subfamily B member 4 3p2t Homo sapiens Eukaryo. plasma 1 0 1.7 ± 0.4 84 ± 5 -5.9
1.3.25.01. Gamma-hemolysin, component B 3lkf Staphylococcus aureus Secreted 1 0 1.7 ± 2.5 51 ± 11 -4.5
2.1.08.01. Quinohemoprotein alcohol dehydrogenase ADH IIB 1kv9 Pseudomonas putida Bact. Gram-neg outer 1 0 1.7 ± 1.1 77 ± 22 -5.9
2.2.36.01. Lactococcin 972 2lgn Lactococcus lactis Secreted 1 0 1.7 ± 2.8 56 ± 9 -3.3
1.2.06.01. Tumor necrosis factor ligand superfamily member 4 2hew Mus musculus Eukaryo. plasma 3 0 1.7 ± 0.3 90 ± 0 -7.9
2.4.06.01. StAR-related lipid transfer protein 5 2r55 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 47 ± 19 -4.8
2.1.01.01. Phospholipase A2, beta bungarotoxin A1 chain, complex with bungarotoxin 1bun Bungarus multicinctus Secreted 2 0 1.7 ± 0.9 79 ± 3 -3.8
2.3.06.01. Neuroligin-2 3bl8 Mus musculus Eukaryo. plasma 1 0 1.7 ± 1.6 32 ± 5 -4.1
3.1.04.07. Peptide (119-148) of antifreeze protein Afp1 2lq2 Glaciozyma antarctica Undefined 1 0 1.7 ± 2.4 84 ± 6 -8.6
2.2.34.12. Poneritoxin, omega-PONTX-Ae1a 2nbc Anochetus emarginatus Secreted 1 0 1.7 ± 1.8 72 ± 12 -2.5
2.2.34.02. Mu-cyrtautoxin-As1a 2m36 Apomastus schlingeri Secreted 1 0 1.7 ± 1.0 49 ± 35 -3.2
2.2.34.01. Conotoxin Gm9 1ixt Conus gloriamaris (Glory-of-the-Seas cone) Secreted 1 0 1.7 ± 1.7 85 ± 17 -3.0
2.4.16.01. Neurotoxin BmK-M10 2kbk Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 1.7 ± 1.0 73 ± 14 -2.4
2.1.01.01. Phospholipase A2 isoform 4 1yxh Naja sagittifera Secreted 1 0 1.7 ± 0.5 81 ± 2 -5.2
3.1.30.01. Lactoferrin-based peptide, 21-67 1z6v Homo sapiens Secreted 1 0 1.7 ± 1.4 84 ± 3 -4.9
2.3.18.01. Carnitine O-octanoyltransferase 1nm8 Homo sapiens Mitochon. inner 1 0 1.7 ± 3.0 67 ± 15 -5.3
1.2.22.01. Bcl-2-like protein 2 1o0l Homo sapiens Mitochon. outer 1 0 1.7 ± 2.3 86 ± 14 -3.7
1.2.39.01. Leucyl-cystinyl aminopeptidase, structure 2 5mj6 Homo sapiens Eukaryo. plasma 1 0 1.8 ± 1.4 76 ± 4 -3.5
3.1.15.01. Sakacin P 1ohm Lactobacillus sake Secreted 1 0 1.8 ± 1.1 90 ± 11 -4.4
2.2.05.01. Plastocyanin 9pcy Phaseolus vulgaris Thylakoid 1 0 1.8 ± 1.6 18 ± 19 -1.9
2.3.06.01. Acetylcholinesterase 1ea5 Torpedo californica Eukaryo. plasma 1 0 1.8 ± 1.1 34 ± 5 -4.7
2.2.34.05. Tachystatin-B1 2dcv Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 1.8 ± 1.1 5 ± 9 -5.9
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4-like 2nsq Homo sapiens Eukaryo. plasma 1 0 1.8 ± 1.1 85 ± 5 -3.3
2.3.14.01. Sec14-like protein 3 4uyb Homo sapiens Vesicle 1 0 1.8 ± 1.8 71 ± 18 -3.3
2.3.06.02. MPT51/MPB51 antigen 1r88 Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 1.8 ± 1.0 28 ± 26 -3.9
2.2.27.01. Kinase supressor of Ras, Ksr 1kbf Mus musculus Eukaryo. plasma 1 0 1.8 ± 1.0 63 ± 11 -5.4
2.1.26.01. Colicin A channel-forming domain 1col Escherichia coli Secreted 1 0 1.8 ± 1.0 43 ± 11 -3.2
2.3.01.09. Arabinogalactan endo-1,4-beta-galactosidase 1hjq Humicola insolens (Soft-rot fungus) Secreted 1 0 1.8 ± 1.4 86 ± 7 -3.7
1.2.32.01. Cholesterol 7-alpha-monooxygenase (P450 7A1) 3dax Homo sapiens Endoplasm. reticulum 1 0 1.8 ± 1.9 69 ± 8 -3.9
2.1.60.01. Potassium channel toxin Bgk 1bgk Bunodosoma granulifera Secreted 1 0 1.8 ± 1.7 19 ± 27 -2.9
2.4.51.01. Heme acquisition protein HasA, dimer 4y4s Yersinia pseudotuberculosis Secreted 1 0 1.8 ± 1.1 83 ± 9 -4.2
3.1.11.02. Extendin-4, variant 5niq Heloderma suspectum Secreted 1 0 1.8 ± 0.8 82 ± 18 -4.4
2.4.16.04. Floral defensin-like protein 1 1n4n Petunia hybrida Secreted 1 0 1.8 ± 0.8 6 ± 9 -3.8
3.2.03.01. Maurocalcine 1s6w Scorpio maurus Secreted 1 0 1.8 ± 1.6 89 ± 21 -2.3
1.1.01.03. Ectodomain of G-protein coupled receptor Mth 1fjr Drosophila melanogaster Eukaryo. plasma 1 0 1.8 ± 1.5 56 ± 13 -4.3
2.4.28.01. Phenazine biosynthesis protein PhzF 1s7j Enterococcus faecalis Undefined 1 0 1.8 ± 0.7 77 ± 2 -4.3
2.1.08.01. Mono-heme c-type cytochrome ScyA 1kx7 Shewanella putrefaciens Bact. Gram-neg inner 1 0 1.8 ± 1.1 72 ± 12 -3.2
1.2.38.02. Lysozyme 3hde Enterobacteria phage p21 Secreted 1 0 1.8 ± 1.4 55 ± 10 -4.7
2.3.06.01. Bile-salt activated lipase, structure 1 1f6w Homo sapiens Secreted 1 0 1.8 ± 0.5 81 ± 10 -5.1
3.4.09.01. Granin 1lv4 Homo sapiens Secreted 1 0 1.8 ± 0.4 81 ± 3 -6.8
2.4.16.03. Insectotoxin-I1 6ava Mesobuthus eupeus Secreted 1 0 1.8 ± 1.6 60 ± 7 -3.8
2.2.01.01. F18 fimbrial adhesin AC, FedF 4b4q Escherichia coli Secreted 1 0 1.8 ± 2.6 81 ± 20 -3.4
2.3.06.16. Lipase lip1 4opm Acinetobacter baumannii Secreted 1 0 1.8 ± 1.0 41 ± 3 -4.4
2.2.21.04. Cytolethal distending toxin complex 1sr4 Haemophilus ducreyi Bact. Gram-neg outer 3 0 1.8 ± 1.5 34 ± 7 -5.0
2.3.06.01. Neuroligin-1, complex with human neurexin-1-alpha 3b3q Mus musculus Eukaryo. plasma 2 0 1.8 ± 1.0 81 ± 1 -3.6
2.1.24.01. Saposin-like protein 5 2jsa Caenorhabditis elegans Secreted 1 0 1.8 ± 2.2 47 ± 0 -3.7
3.2.10.02. PLP-12 peptide 6awk Designed proteins Undefined 1 0 1.8 ± 1.8 80 ± 12 -4.4
2.2.41.01. Defensin-like peptide 1 1b8w Ornithorhynchus anatinus Secreted 1 0 1.8 ± 0.6 84 ± 2 -4.4
3.2.10.01. PawS derived peptide 20 2ndn Zinnia haageana Secreted 1 0 1.8 ± 0.7 83 ± 11 -4.6
2.1.20.01. Osteocalcin 4mzz Bos taurus Secreted 1 0 1.8 ± 1.1 43 ± 8 -3.0
2.2.34.02. Robustoxin 1qdp Atrax robustus Secreted 1 0 1.8 ± 1.9 86 ± 18 -5.0
3.1.20.01. Conotoxin Ar1446 2m61 Conus araneosus Secreted 1 0 1.8 ± 0.8 82 ± 6 -4.0
3.2.10.01. PawS derived peptide 21 2ndm Zinnia haageana Secreted 1 0 1.9 ± 1.2 83 ± 16 -3.7
1.2.03.07. Netrin receptor UNC5B 3g5b Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 2.5 90 ± 14 -8.5
3.2.02.02. Chi-conotoxin Ar1248 2m62 Conus araneosus Secreted 1 0 1.9 ± 1.0 78 ± 12 -3.0
2.3.16.07. Ras-related protein Rab-9A 1wms Homo sapiens Eukaryo. plasma 1 0 1.9 ± 0.8 48 ± 7 -5.0
2.3.01.04. Hyaluronidase 1fcq Apis mellifera Secreted 1 0 1.9 ± 2.7 36 ± 13 -3.7
2.3.05.03. D-amino-acid oxidase 1ve9 Sus scrofa Peroxisome 2 0 1.9 ± 2.5 88 ± 4 -4.8
3.1.11.02. Extendin-4, with extracellular domain of glucagon-like peptide-1 GPCR 3c59 Heloderma suspectum Secreted 2 0 1.9 ± 0.2 64 ± 0 -6.5
2.2.06.02. Intestinal fatty acid binding protein, structure 4 2mo5 Homo sapiens Eukaryo. plasma 1 0 1.9 ± 1.3 59 ± 6 -3.4
2.2.34.02. U1-TRTX-Sp1a toxin 2ll1 Selenotypus plumipes Secreted 1 0 1.9 ± 3.4 50 ± 5 -3.6
2.2.06.02. Retinol-binding protein 2 1opb Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 1.4 25 ± 7 -3.6
2.2.39.01. Erabutoxin b 3ebx Laticauda semifasciata (Black-banded sea krait) Secreted 1 0 1.9 ± 1.4 47 ± 11 -4.3
2.4.16.01. Tx10 alpha-like toxin 1kv0 Buthus martensii Secreted 1 0 1.9 ± 1.1 83 ± 11 -4.6
1.2.39.01. Endoplasmic reticulum aminopeptidase 1 3mdj Homo sapiens Endoplasm. reticulum 1 0 1.9 ± 3.6 63 ± 10 -4.6
2.4.51.01. Heme acquisition protein HasA 1b2v Serratia marcescens Secreted 1 0 1.9 ± 1.6 18 ± 18 -3.3
2.4.16.04. Defensin 1ti5 Vigna radiata (Mung bean) Secreted 1 0 1.9 ± 2.4 62 ± 16 -3.0
2.2.20.01. Rho guanine nucleotide exchange factor 9, conformation 1 4mt7 Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 2.6 52 ± 14 -3.9
2.4.10.01. Synapsin I 1auv Bos taurus Vesicle 1 0 1.9 ± 1.1 86 ± 11 -5.2
2.3.06.06. Triacylglycerol lipase 1lgy Rhizopus niveus Secreted 1 0 1.9 ± 1.8 33 ± 16 -4.8
2.2.34.09. Psi-conotoxin PIIIE 1as5 Conus purpurascens (Purple cone) Secreted 1 0 1.9 ± 1.3 87 ± 11 -3.6
3.1.34.01. Conantokin-R1-B 2mzm Conus rolani Secreted 1 0 1.9 ± 0.7 81 ± 8 -2.9
2.2.16.01. Lipoprotein lppX 2byo Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 1.9 ± 1.7 80 ± 13 -4.8
3.1.05.03. Human platelet factor 4 based peptide, 56-70, modified 1djf Designed proteins Undefined 1 0 1.9 ± 1.4 87 ± 8 -4.9
2.4.06.01. First StARkin domain of Lam2 5yqi Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.9 ± 1.6 30 ± 8 -4.1
3.4.09.01. Granin, cyclic analogue 1n2y Bos taurus Secreted 1 0 1.9 ± 2.1 71 ± 16 -3.4
2.1.01.01. Snake phospholipase A2 homolog 2, group II 2q2j Bothrops pirajai Secreted 1 0 1.9 ± 1.2 89 ± 9 -5.6
2.2.06.01. Retinol binding protein, plasma isoform 1iiu Gallus gallus Secreted 1 0 1.9 ± 1.8 35 ± 17 -4.4
2.2.34.01. Mu-conotoxin GS 1ag7 Conus geographus (Geography cone) Secreted 1 0 1.9 ± 1.0 68 ± 15 -2.6
3.1.20.01. Alpha-conotoxin ImI 1e75 Conus imperialis (Imperial cone) Secreted 1 0 1.9 ± 0.9 80 ± 15 -3.7
2.3.06.17. Group XV phospholipase A2 4x90 Homo sapiens Lysosome 1 0 1.9 ± 0.5 56 ± 1 -7.3
3.4.02.02. Mersacidin, structure in methanol solution 1mqx Bacillus sp. Secreted 1 0 1.9 ± 1.3 87 ± 15 -2.9
2.3.06.19. Lipase A 1isp Bacillus subtilis Secreted 1 0 1.9 ± 0.8 59 ± 12 -5.2
3.1.02.03. Juxtamembrane helix of ATP synthase subunit b 2khk Escherichia coli Bact. Gram-neg inner 1 0 1.9 ± 0.1 85 ± 3 -3.9
2.1.01.01. Phospholipase A2, group IB 1g4i Bos taurus Secreted 1 0 1.9 ± 0.5 87 ± 4 -7.4
2.1.36.01. Endoplasmic reticulum oxidoreductin, a mutant 3m31 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.9 ± 1.2 27 ± 9 -6.2
2.2.06.01. Complement component C8 gamma chain 1lf7 Homo sapiens Secreted 1 0 1.9 ± 2.2 43 ± 12 -2.6
2.1.35.01. Protein kinase C and casein kinase substrate 3lll Mus musculus Vesicle 2 0 1.9 ± 0.4 88 ± 1 -5.4
2.2.34.02. U1-theraphotoxin-Ba1b 2kgh Brachypelma ruhnaui (Mexican golden redrump tarantula) Secreted 1 0 1.9 ± 2.5 83 ± 25 -1.9
2.3.06.01. Neuroligin-4, X-linked, complex with neurexin 1-beta 2xb6 Homo sapiens Eukaryo. plasma 2 0 1.9 ± 3.0 84 ± 11 -3.3
1.2.36.01. Hemagglutinin-neuraminidase glycoprotein 1v3e Human parainfluenza virus 3 Eukaryo. plasma 2 0 1.9 ± 0.4 81 ± 34 -6.5
2.2.20.01. Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 4a6f Saccharomyces cerevisiae Eukaryo. plasma 1 0 1.9 ± 1.6 62 ± 4 -6.1
2.2.20.01. Son of sevenless homolog 1 (SOS-1) 1xd4 Homo sapiens Eukaryo. plasma 1 0 1.9 ± 3.0 79 ± 2 -4.5
2.1.20.01. Coagulation factor IX 1pfx Sus scrofa Eukaryo. plasma 2 0 1.9 ± 6.0 84 ± 10 -3.9
2.3.19.01. Toxin B 2bvl Clostridium difficile Secreted 1 0 2.0 ± 1.1 24 ± 14 -4.2
2.3.25.02. GDSL-like lipase 3p94 Parabacteroides distasonis Secreted 1 0 2.0 ± 2.0 68 ± 6 -4.2
2.2.07.01. Lipocalin BcnB 5ixg Burkholderia cepacia Bact. Gram-neg inner 1 0 2.0 ± 1.0 36 ± 5 -3.9
2.4.16.08. Hydramacin-1 2k35 Hydra vulgaris Secreted 1 0 2.0 ± 0.2 87 ± 2 -4.3
2.2.05.01. Plastocyanin 1bxv Synechocystis sp. Thylakoid 1 0 2.0 ± 1.6 36 ± 19 -2.6
3.2.10.01. PawS derived peptide 7 2lwu Designed proteins Undefined 1 0 2.0 ± 1.4 81 ± 10 -3.0
2.2.06.01. Neutrophil gelatinase-associated lipocalin 3fw5 Homo sapiens Secreted 1 0 2.0 ± 1.2 45 ± 9 -3.1
1.2.01.01. Receptor tyrosine-protein kinase erbB-3, extracellular domains 1m6b Homo sapiens Eukaryo. plasma 1 0 2.0 ± 1.6 45 ± 5 -3.9
3.2.04.02. Bowman-Birk type proteinase inhibitor peptide 1gm2 Macrotyloma axillare Secreted 1 0 2.0 ± 1.9 59 ± 14 -3.5
2.4.38.01. Ups1 transporter-Mdm35 complex, structure 1 4xiz Saccharomyces cerevisiae Mitochon. inner 2 0 2.0 ± 1.7 19 ± 13 -4.1
2.4.06.01. Lipid transport protein Mln64 (StARD3) 1em2 Homo sapiens Endosome 1 0 2.0 ± 1.1 82 ± 12 -5.0
2.1.08.01. Cytochrome c2 1cxa Rhodobacter sphaeroides Bact. Gram-neg inner 1 0 2.0 ± 1.2 88 ± 13 -4.3
2.1.60.01. Aurelin 2lg4 Aurelia aurita Secreted 1 0 2.0 ± 0.9 50 ± 6 -4.4
2.3.06.01. Acetylcholinesterase 4qww Bungarus fasciatus Secreted 1 0 2.0 ± 1.5 36 ± 32 -3.0
2.1.01.01. Phospholipase A2, group IIE 5wzm Homo sapiens Secreted 1 0 2.0 ± 2.0 88 ± 2 -6.6
2.1.36.01. Endoplasmic reticulum oxidoreductin 1rp4 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.0 ± 1.8 16 ± 9 -4.7
2.2.11.01. Protein kinase C delta 1yrk Homo sapiens Eukaryo. plasma 1 0 2.0 ± 1.6 52 ± 19 -1.8
3.2.01.07. Cyclic beta-hairpin peptide 2m7i Designed proteins Secreted 1 0 2.0 ± 0.5 84 ± 8 -4.1
2.3.14.01. Retinaldehyde-binding protein 1, closed state, more complete structure 3hy5 Homo sapiens Eukaryo. plasma 1 0 2.0 ± 3.9 55 ± 17 -4.5
2.3.17.02. Folic acid synthesis protein FOL1 2bmb Saccharomyces cerevisiae Mitochon. inner 1 0 2.0 ± 0.6 31 ± 2 -5.8
1.2.03.02. SLAM family member 6 2if7 Homo sapiens Eukaryo. plasma 3 0 2.0 ± 3.3 88 ± 11 -7.1
2.1.24.01. Saposin A (peptide 60-140) 2dob Homo sapiens Lysosome 1 0 2.0 ± 2.5 70 ± 29 -4.2
3.1.11.03. Obestatin 2jsi Mus musculus Secreted 1 0 2.0 ± 3.3 85 ± 13 -3.1
2.3.31.01. Sorbose-specific phosphotransferase enzyme IIB component 1nrz Klebsiella pneumoniae Bact. Gram-neg inner 1 0 2.1 ± 0.7 83 ± 3 -4.5
2.3.18.01. Choline O-acetyltransferase, different conformation 1t1u Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 1.7 73 ± 15 -6.8
2.2.27.01. C1 domain of protein kinase C alpha 2eli Homo sapiens Eukaryo. plasma 1 0 2.1 ± 0.4 23 ± 4 -7.4
3.1.29.01. Cathelicidin-5 2ndc Bos taurus Secreted 1 0 2.1 ± 2.1 82 ± 17 -3.7
2.1.08.01. Mitochondrial cytochrome c 1hrc Equus caballus Mitochon. inner 1 0 2.1 ± 1.0 80 ± 16 -2.6
2.3.19.02. Histo-blood group ABO system transferase 2rj6 Homo sapiens Golgi 1 0 2.1 ± 1.3 77 ± 3 -7.1
2.1.18.01. Annexin I 1hm6 Sus scrofa Vesicle 1 0 2.1 ± 0.9 88 ± 7 -5.6
2.4.50.01. Matrix protein, Indiana virus, complex with mRNA export factor 4owr Vesicular stomatitis virus Viral 1 0 2.1 ± 0.8 65 ± 2 -7.6
3.2.01.01. Arenicin-2 2jni Arenicola marina Secreted 1 0 2.1 ± 1.1 82 ± 15 -5.2
2.1.60.02. Potassium channel blocking domain of matrix metalloproteinase-23 2k72 Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 2.3 77 ± 22 -4.4
2.3.25.01. Acyloxyacyl hydrolase, structure 2 5w78 Homo sapiens Secreted 2 0 2.1 ± 0.8 80 ± 2 -3.7
2.2.34.09. Psi-conotoxin PIIIF 1jlp Conus purpurascens (Purple cone) Secreted 1 0 2.1 ± 1.1 72 ± 30 -3.1
2.1.25.02. Carnocyclin A 2kjf Carnobacterium maltaromaticum Secreted 1 0 2.1 ± 1.1 61 ± 12 -4.6
3.4.08.03. Oxytocin 1xy2 Bos taurus Secreted 1 0 2.1 ± 2.6 86 ± 12 -3.2
3.2.01.05. Protegrin-2 2muh Sus scrofa Secreted 1 0 2.1 ± 3.3 88 ± 2 -3.2
1.2.44.01. Amyloid beta A4 protein (peptide 672-699) 1amb Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 87 ± 0 -3.2
3.1.04.08. Truncated superoxide dismutase 1 2mp3 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 83 ± 0 -6.3
2.2.60.01. Matrix protein VP40 1es6 Zaire ebolavirus Viral 1 0 2.1 ± 0.5 80 ± 3 -6.7
2.1.02.01. Arachidonate 5-lipoxygenase 3o8y Homo sapiens Eukaryo. plasma 1 0 2.1 ± 1.0 89 ± 4 -3.8
3.4.04.03. Tridecaptin A1 2n5y Designed proteins Undefined 1 0 2.1 ± 1.0 89 ± 7 -3.9
3.1.03.07. N-terminal peptide (24-58) of Disabled homolog 2 2lsw Homo sapiens Vesicle 1 0 2.1 ± 0.6 85 ± 5 -3.8
2.4.07.01. Bud emergence protein 1 2v6v Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.1 ± 1.2 75 ± 6 -5.1
2.3.06.12. Lipase/esterase 3bjr Lactobacillus plantarum Secreted 1 0 2.1 ± 0.2 72 ± 5 -7.0
2.1.18.01. Annexin V 1a8a Rattus norvegicus Eukaryo. plasma 3 0 2.1 ± 1.1 89 ± 10 -8.9
3.1.11.05. Parathyroid hormone 1et1 Homo sapiens Secreted 1 0 2.1 ± 0.5 85 ± 3 -5.6
2.2.20.01. Dynamin-2 2ys1 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 0.4 49 ± 3 -5.3
1.1.49.01. ATP-dependent zinc metalloprotease FtsH 1lv7 Escherichia coli Bact. Gram-neg inner 1 0 2.1 ± 1.0 80 ± 11 -4.3
2.2.27.01. Beta-chimaerin 1xa6 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 1.7 65 ± 7 -5.1
2.4.16.01. Alpha-toxin Cn12 1pe4 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.1 ± 2.3 17 ± 13 -3.1
3.1.21.06. Spinigerin 1zrv Pseudacanthotermes spiniger Secreted 1 0 2.1 ± 3.4 77 ± 5 -3.9
2.1.01.01. Snake phospholipase A2 crotoxin basic chain 2, group II 2qog Crotalus durissus terrificus Secreted 1 0 2.1 ± 1.1 84 ± 8 -7.2
3.1.11.06. Parathyroid hormone-related peptide, structure 2 3ffd Homo sapiens Secreted 1 0 2.2 ± 1.5 89 ± 3 -5.1
2.1.61.01. Muramidase Tse3-Tsi3 complex, conformation 2 4luq Pseudomonas aeruginosa Bact. Gram-neg outer 2 0 2.2 ± 1.4 69 ± 5 -8.2
1.2.04.01. Integrin alpha-L, cytoplasmic domain (1113-1170) 2k8o Homo sapiens Eukaryo. plasma 1 0 2.2 ± 0.7 65 ± 3 -3.7
2.2.20.01. PH domain of docking protein 2 2d9w Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.2 13 ± 17 -3.5
2.4.34.01. Ice-structuring protein RD1 1ucs Lycodichthys dearborni Secreted 1 0 2.2 ± 1.0 67 ± 9 -5.5
3.2.06.01. Paralytic peptide 1irr Bombyx mori Secreted 1 0 2.2 ± 1.9 74 ± 19 -3.3
2.3.04.01. Sorbitol dehydrogenase 1k2w Rhodobacter sphaeroides Bact. Gram-neg inner 2 0 2.2 ± 0.3 89 ± 1 -4.4
2.2.20.01. Fermitin family homolog 2 4f7h Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.4 72 ± 4 -4.2
1.2.03.03. Myelin protein P0 3oai Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.2 72 ± 6 -5.8
2.2.11.01. Synaptotagmin-7 3n5a Mus musculus Vesicle 1 0 2.2 ± 2.3 30 ± 12 -4.1
2.2.34.07. Asteropsin B 2lzx Asteropus sp. Secreted 1 0 2.2 ± 1.7 90 ± 21 -3.3
2.2.41.01. Alpha-defensin 4 1zmm Homo sapiens Secreted 1 0 2.2 ± 1.0 76 ± 10 -5.5
1.2.43.06. Outer capsid protein VP4, dimer 2b4h Rotavirus A Viral 2 0 2.2 ± 0.2 4 ± 1 -8.3
2.2.12.03. Immunogenic protein MPT63 1lmi Mycobacterium tuberculosis Secreted 1 0 2.2 ± 1.9 86 ± 7 -4.3
2.2.20.01. Rho guanine nucleotide exchange factor 4 2dx1 Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.2 80 ± 10 -3.6
2.2.34.02. Mu-theraphotoxin-Hhn1b 1niy Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.2 ± 0.7 71 ± 6 -4.6
3.2.06.01. Growth-blocking peptide 2dj9 Mamestra brassicae Secreted 1 0 2.2 ± 0.7 31 ± 4 -6.2
2.3.13.03. Thiol-disulfide interchange protein DsbA 1u3a Escherichia coli Bact. Gram-neg inner 1 0 2.2 ± 1.4 86 ± 8 -4.2
2.1.18.01. Annexin IV, monomeric state 1ann Bos taurus Eukaryo. plasma 1 0 2.2 ± 1.0 77 ± 3 -6.0
3.2.01.06. Lactoferricin B, peptide 10-19 1y5c Bos taurus Secreted 1 0 2.2 ± 1.2 54 ± 11 -3.4
2.3.13.02. Phosducin/Transducin beta-gamma complex, conformation 2 2trc Rattus norvegicus Eukaryo. plasma 3 0 2.2 ± 1.0 62 ± 10 -4.9
2.2.11.01. Protein kinase C eta, C2 domain 2fk9 Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.1 57 ± 6 -5.0
2.1.24.01. Saposin D (peptide 405-486) 2rb3 Homo sapiens Secreted 1 0 2.2 ± 1.7 88 ± 10 -3.4
2.3.02.01. Phospholipase C-beta isoform 2 2zkm Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.9 38 ± 12 -3.6
3.2.01.05. Protegrin-1 1pg1 Sus scrofa Secreted 1 0 2.2 ± 0.4 72 ± 4 -4.2
2.1.01.01. Snake phospholipase A2, group I, isoform 2 1u4j Bungarus caeruleus Secreted 1 0 2.2 ± 0.6 83 ± 4 -8.5
2.2.34.01. Conotoxin TVIIA 1eyo Conus tulipa (Fish-hunting cone snail) Secreted 1 0 2.2 ± 0.7 74 ± 9 -4.6
1.2.50.01. Fragaceatoxin C, complex with lipids 4tsq Actinia fragacea (Strawberry anemone) Secreted 1 0 2.2 ± 0.9 38 ± 3 -15.5
2.2.11.01. Synaptotagmin-13 1wfm Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.9 88 ± 15 -4.5
1.2.39.02. Matrilysin, structure 3 2mzh Homo sapiens Secreted 1 0 2.2 ± 1.6 67 ± 22 -6.4
2.2.33.01. Antimicrobial peptide 1b 2lb7 Triticum kiharae (Wheat) Secreted 1 0 2.2 ± 0.7 89 ± 7 -2.5
2.2.20.01. PH domain of Src-associated adaptor protein 2 homologue 1u5f Mus musculus Eukaryo. plasma 2 0 2.2 ± 2.0 56 ± 12 -4.9
2.4.16.04. Defensin Lc-def 2lj7 Lens culinaris Secreted 1 0 2.2 ± 0.9 22 ± 10 -3.9
1.2.33.02. Protoporphyrinogen oxidase 1sez Nicotiana tabacum Mitochon. inner 1 0 2.2 ± 1.0 50 ± 3 -7.0
2.1.08.01. Cytochrome c peroxidase 1nml Marinobacter hydrocarbonoclasticus Bact. Gram-neg inner 1 0 2.2 ± 0.4 83 ± 0 -7.9
3.2.02.02. Chi-conotoxin MrIB 1ieo Conus marmoreus Secreted 1 0 2.2 ± 1.1 45 ± 12 -1.9
2.1.24.01. Saposin-like protein Na-SLP-1 3s63 Necator americanus Secreted 1 0 2.2 ± 1.6 74 ± 10 -3.5
2.4.11.01. Hellethionin D 1nbl Helleborus purpurascens Secreted 1 0 2.2 ± 0.9 45 ± 9 -7.4
1.1.49.01. ATP-dependent zinc metalloprotease FtsH 3kds Thermotoga maritima Bact. Gram-neg inner 6 0 2.2 ± 0.4 90 ± 0 -12.8
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4, complex with GRB10 3m7f Mus musculus Eukaryo. plasma 2 0 2.2 ± 2.0 76 ± 13 -2.7
2.4.06.01. Acyl-coenzyme A thioesterase 11 3fo5 Homo sapiens Endoplasm. reticulum 1 0 2.3 ± 1.4 57 ± 7 -3.9
3.1.21.01. Cecropin A (1-8) - magainin (1-12) hybrid 1d9j Hyalophora cecropia (Cecropia moth) Secreted 1 0 2.3 ± 0.9 90 ± 10 -6.4
1.2.43.01. Envelope glycoprotein, Zika virus, structure 5 5lbs Zika virus Viral 1 0 2.3 ± 2.5 62 ± 5 -4.7
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1t27 Rattus norvegicus Eukaryo. plasma 1 0 2.3 ± 1.9 12 ± 12 -4.1
3.1.12.01. Sarafotoxin-M 2ldf Atractaspis microlepidota microlepidota Secreted 1 0 2.3 ± 1.5 30 ± 35 -2.1
3.4.04.01. Daptomycin, Ca-free, different conformation 1t5m Streptomyces roseosporus Secreted 1 0 2.3 ± 1.3 33 ± 6 -7.9
2.1.20.01. Osteocalcin 1q8h Sus scrofa Secreted 1 0 2.3 ± 1.7 81 ± 17 -4.4
2.3.13.02. Phosducin/Transducin beta-gamma complex, conformation 1 1a0r Bos taurus Eukaryo. plasma 3 0 2.3 ± 1.0 50 ± 4 -7.4
2.1.18.01. Annexin D1 1ycn Arabidopsis thaliana Eukaryo. plasma 1 0 2.3 ± 1.1 78 ± 14 -3.4
2.2.12.05. Glucans biosynthesis protein G 1txk Escherichia coli Bact. Gram-neg inner 1 0 2.3 ± 0.7 80 ± 8 -5.1
2.2.11.01. Synaptotagmin-7, C2A- and C2B-domains 6ank Rattus norvegicus Eukaryo. plasma 1 0 2.3 ± 0.6 66 ± 6 -5.2
2.2.20.01. PH domain of muscle M-line assembly protein unc-89 1fho Caenorhabditis elegans Eukaryo. plasma 1 0 2.3 ± 1.2 25 ± 14 -4.3
2.4.16.01. Alpha-toxin CsE5 1nra Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.3 ± 1.2 89 ± 22 -4.3
2.1.21.01. Influenza virus matrix protein M1, structure 2 4pus Influenza virus Viral 2 0 2.3 ± 1.6 81 ± 3 -9.4
2.3.05.02. Adrenodoxin reductase of mitochondrial p450 systems, complex with adrenodoxin 1e6e Bos taurus Mitochon. inner 2 0 2.3 ± 1.0 11 ± 2 -4.1
2.1.18.01. Annexin V 1hvf Homo sapiens Eukaryo. plasma 1 0 2.3 ± 1.5 79 ± 10 -5.4
2.3.06.05. Carboxylesterase 2h1i Bacillus cereus Bact. Gram-pos plas. 1 0 2.3 ± 1.8 32 ± 31 -3.6
2.3.01.01. Glucosylceramidase 2vt0 Pan troglodytes Lysosome 1 0 2.3 ± 1.0 86 ± 5 -7.3
2.2.12.01. Lymphocyte antigen 86 3mtx Gallus gallus Secreted 1 0 2.3 ± 1.6 69 ± 11 -2.4
2.4.27.01. Gamma-glutamylaminecyclotransferase 1vkb Mus musculus Undefined 1 0 2.3 ± 0.7 72 ± 4 -4.8
2.4.11.01. Viscotoxin A1 3c8p Viscum album Secreted 1 0 2.3 ± 0.9 45 ± 7 -4.9
3.2.01.05. Protegrin-5 2nc7 Sus scrofa Secreted 1 0 2.3 ± 1.2 87 ± 6 -2.4
2.1.02.01. 8R-Lipoxygenase, complete structure 3dy5 Plexaura homomalla Eukaryo. plasma 1 0 2.3 ± 1.5 88 ± 10 -3.2
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3a 5fc1 Mus musculus Secreted 1 0 2.3 ± 3.0 62 ± 17 -4.8
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, delta isoform 2wxf Mus musculus Eukaryo. plasma 1 0 2.3 ± 1.8 89 ± 3 -5.3
1.2.64.01. Selenoprotein S 5kiu Homo sapiens Endoplasm. reticulum 1 0 2.3 ± 4.2 89 ± 0 -5.2
2.4.11.01. Viscotoxin A2 1jmn Viscum album Secreted 1 0 2.3 ± 0.3 63 ± 8 -3.3
1.2.50.01. Sticholysin-1 2ks4 Stoichactis helianthus Secreted 1 0 2.3 ± 2.2 6 ± 24 -5.7
2.2.11.01. C2A domain of synaptotagmin-5 5h4y Homo sapiens Vesicle 1 0 2.3 ± 2.3 29 ± 11 -4.5
2.2.06.02. Cellular retinol-binding protein II 1crb Rattus norvegicus Eukaryo. plasma 1 0 2.4 ± 1.7 52 ± 19 -5.3
1.2.22.01. Activator of apoptosis harakiri, cytosolic helix 2l58 Homo sapiens Mitochon. outer 1 0 2.4 ± 4.0 88 ± 0 -8.5
2.4.34.01. Ice-structuring protein SP2(HPLC 1) 1ops Zoarces americanus Secreted 1 0 2.4 ± 1.4 60 ± 12 -4.8
3.2.05.02. Astexin-1, structure 1 2lti Asticcacaulis excentricus Secreted 1 0 2.4 ± 1.0 85 ± 9 -3.6
2.1.01.03. Prokaryotic phospholipase A2 1kp4 Streptomyces violaceoruber Secreted 1 0 2.4 ± 1.3 42 ± 13 -5.6
2.2.34.11. Violacin 1 2fqa Viola odorata Secreted 1 0 2.4 ± 3.4 70 ± 46 -4.0
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens Endosome 1 0 2.4 ± 1.6 88 ± 12 -4.6
2.2.25.01. Superoxide dismutase [Cu-Zn] 1oal Photobacterium leiognathi Bact. Gram-neg inner 1 0 2.4 ± 0.9 77 ± 2 -6.8
2.2.11.01. C2 domain of otoferlin 3l9b Rattus norvegicus Vesicle 1 0 2.4 ± 5.2 16 ± 33 -3.4
3.2.05.02. Acinetodin 5ui6 Acinetobacter gyllenbergii Secreted 1 0 2.4 ± 1.6 70 ± 16 -2.7
2.1.29.06. Perilipin-3 1szi Mus musculus Endosome 1 0 2.4 ± 2.3 61 ± 6 -4.1
3.2.01.01. Arenicin-1 2jsb Arenicola marina Secreted 1 0 2.4 ± 2.1 80 ± 11 -5.2
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form, mutant 4os0 Homo sapiens Endoplasm. reticulum 1 0 2.4 ± 1.0 77 ± 4 -3.1
2.2.37.01. Primary amine oxidase, liver isozyme 1tu5 Bos taurus Secreted 2 0 2.4 ± 1.2 89 ± 0 -6.1
2.2.20.01. Dual adaptor of phosphotyrosine and 3-phosphoinositides 1fao Homo sapiens Eukaryo. plasma 1 0 2.4 ± 2.0 59 ± 19 -3.9
3.2.01.04. Retrocyclin-2 (HTD-2) 2atg Macaca mulatta Secreted 1 0 2.4 ± 0.6 87 ± 9 -5.6
2.2.34.02. Psalmotoxin-1 1lmm Psalmopoeus cambridgei (Trinidad chevron tarantula) Secreted 1 0 2.4 ± 1.6 71 ± 15 -4.4
2.1.18.01. Annexin II 1w7b Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.2 87 ± 18 -3.8
2.2.34.02. Neurotoxin Hm-3 2mqu Heriaeus melloteei Secreted 1 0 2.4 ± 0.6 75 ± 11 -7.4
2.3.08.01. Patatin-like protein, PlpD 5fqu Pseudomonas aeruginosa Secreted 2 0 2.4 ± 0.6 90 ± 3 -5.6
3.1.20.01. Alpha-conotoxin Vc1A 2h8s Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.8 59 ± 6 -2.5
2.4.11.01. Alpha-1-purothionin 2plh Triticum aestivum Secreted 1 0 2.4 ± 2.0 53 ± 17 -4.6
3.1.20.01. O2-contryphan-Vc2 5l34 Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.4 85 ± 8 -4.2
1.2.50.01. Fragaceatoxin C, trimer 3zwj Actinia fragacea (Strawberry anemone) Secreted 3 0 2.4 ± 0.2 89 ± 4 -8.4
3.1.20.01. Alpha-conotoxin PIVA 1p1p Conus purpurascens (Purple cone) Secreted 1 0 2.4 ± 1.0 30 ± 11 -3.8
2.1.01.01. Snake phospholipase A2, isoform 3 2osn Bungarus caeruleus Secreted 1 0 2.4 ± 0.6 84 ± 4 -5.8
3.2.05.02. Caulonodin 2mlj Caulobacter sp. Secreted 1 0 2.4 ± 1.7 87 ± 15 -5.0
2.3.01.02. Dhurrinase 1v02 Sorghum bicolor Secreted 2 0 2.4 ± 0.5 89 ± 9 -5.1
2.2.34.02. Delta-amaurobitoxin-Pl1b 1v91 Pireneitega luctuosa (Tangled nest spider) Secreted 1 0 2.4 ± 0.9 35 ± 4 -5.7
2.2.08.01. Osmotin 1pcv Nicotiana tabacum Secreted 1 0 2.4 ± 1.9 82 ± 19 -2.7
2.1.31.01. Colicin M, alternative orientation 2xmx Escherichia coli Secreted 1 0 2.4 ± 2.3 82 ± 4 -4.8
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 1 2w61 Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.4 ± 2.3 60 ± 7 -5.4
2.3.05.02. Sulfide-quinone reductase 3h28 Aquifex aeolicus Bact. Gram-neg inner 3 0 2.4 ± 0.1 90 ± 0 -19.4
2.2.11.01. Extended synaptotagmin-2, third C2 domain 2dmg Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.0 76 ± 5 -4.8
2.4.15.01. Protein Nef, complex with tyrosine-protein kinase SH3 domain (HIV HV1A2) 3rbb Human immunodeficiency virus type 1 Eukaryo. plasma 2 0 2.4 ± 1.1 84 ± 6 -4.2
2.3.06.12. Esterase LipW 3qh4 Mycobacterium marinum Bact. Gram-pos plas. 1 0 2.4 ± 1.2 76 ± 32 -5.0
1.2.01.01. Insulin-like growth factor 1 receptor 1p4o Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.0 37 ± 11 -5.1
2.1.01.01. Myotoxin 1mc2 Agkistrodon acutus Secreted 1 0 2.4 ± 0.1 80 ± 2 -9.4
3.1.05.03. VG16KRKP peptide, structure 1 2mxh Designed proteins Undefined 1 0 2.5 ± 2.4 82 ± 11 -3.2
2.2.34.02. S64 4b2v Sicarius dolichocephalus Secreted 1 0 2.5 ± 0.5 71 ± 2 -4.3
3.1.05.03. VG16KRKP peptide, structure 2 2n63 Designed proteins Undefined 1 0 2.5 ± 0.3 57 ± 4 -4.0
3.4.10.01. Methanobactin 4oz7 Methylosinus sporium Secreted 1 0 2.5 ± 1.4 86 ± 15 -4.5
2.1.45.01. Kinetoplastid membrane protein 11 5y70 Trypanosoma brucei Eukaryo. plasma 1 0 2.5 ± 0.4 53 ± 4 -4.9
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 3 5fih Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.5 ± 0.6 89 ± 1 -5.3
1.2.37.01. ADP-ribosyl cyclase 1 3f6y Homo sapiens Eukaryo. plasma 1 0 2.5 ± 2.4 51 ± 9 -6.3
2.2.20.01. PH domain of oxysterol-binding protein homolog 3, fused with lysozyme 4iap Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.5 ± 2.3 81 ± 3 -3.6
1.2.32.01. Cytochrome P450 2C9, structure 3 5w0c Homo sapiens Endoplasm. reticulum 1 0 2.5 ± 3.0 43 ± 3 -5.0
2.2.11.01. Synaptotagmin-1 1rsy Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 1.6 24 ± 17 -4.1
2.2.34.03. Toxin Ptu1 1i26 Peirates turpis (Assassin bug) Secreted 1 0 2.5 ± 0.9 52 ± 7 -3.6
2.3.16.02. Translocation ATPase SecA 1tf5 Bacillus subtilis Bact. Gram-pos plas. 1 0 2.5 ± 1.1 64 ± 5 -7.0
1.2.39.01. Endoplasmic reticulum aminopeptidase 2 3se6 Homo sapiens Endoplasm. reticulum 1 0 2.5 ± 1.8 60 ± 21 -4.5
3.2.05.02. Klebsidin 5ui7 Klebsiella pneumoniae Secreted 1 0 2.5 ± 1.4 62 ± 11 -3.7
2.2.11.01. Rabphilin-3A, C2B domain 2cm5 Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 2.0 56 ± 14 -4.1
2.1.48.01. Glycerol dehydrogenase 1kq3 Thermotoga maritima Undefined 1 0 2.5 ± 1.8 80 ± 5 -4.3
2.3.16.08. Interferon-inducible GTPase 1 1tpz Mus musculus Endoplasm. reticulum 1 0 2.5 ± 2.0 37 ± 7 -5.0
2.4.07.01. PX domain of sorting nexin GRD19, ligand-free 1ocs Saccharomyces cerevisiae Endosome 1 0 2.5 ± 1.1 88 ± 11 -5.4
2.3.17.02. Dihydropteroate synthase 1tx2 Bacillus anthracis Bact. Gram-pos plas. 2 0 2.5 ± 0.3 90 ± 2 -7.7
2.4.07.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Homo sapiens Golgi 1 0 2.5 ± 1.3 56 ± 16 -4.8
1.2.57.01. Reticulon-4 2ko2 Mus musculus Endoplasm. reticulum 1 0 2.5 ± 0.3 83 ± 1 -6.2
1.2.17.02. Synaptobrevin homolog YKT6 3kyq Rattus norvegicus Vesicle 1 0 2.5 ± 2.0 53 ± 8 -4.9
2.3.06.15. Polyneuridine-aldehyde esterase 2wfm Rauvolfia serpentina (Serpentwood) Endoplasm. reticulum 1 0 2.5 ± 1.7 88 ± 3 -4.6
2.1.29.01. Apolipoprotein E 2l7b Homo sapiens Secreted 1 0 2.5 ± 1.0 73 ± 8 -4.9
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform 1e7u Sus scrofa Eukaryo. plasma 1 0 2.5 ± 0.9 85 ± 3 -4.7
2.2.11.01. Synaptotagmin-4 1ugk Homo sapiens Eukaryo. plasma 1 0 2.5 ± 1.7 34 ± 11 -3.5
2.1.18.01. Annexin IV 1i4a Bos taurus Eukaryo. plasma 3 0 2.5 ± 1.1 89 ± 3 -7.7
2.2.41.01. Gallinacin-7 5lcs Gallus gallus Secreted 1 0 2.5 ± 1.4 85 ± 5 -5.6
2.2.20.01. Rho GTPase-activating protein 27 3pp2 Homo sapiens Eukaryo. plasma 1 0 2.5 ± 2.2 72 ± 14 -3.4
3.4.08.04. Dynorphin A (1-13) 2n2f Homo sapiens Secreted 1 0 2.5 ± 3.6 78 ± 6 -4.6
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 2 4ph7 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.5 ± 0.9 75 ± 2 -6.4
2.1.31.01. Colicin-M 3da4 Escherichia coli Bact. Gram-neg inner 1 0 2.5 ± 0.9 49 ± 11 -5.5
2.2.06.02. Adipocyte lipid-binding protein 1tow Homo sapiens Eukaryo. plasma 1 0 2.5 ± 1.7 51 ± 18 -4.5
2.3.24.01. Phosphatase YidA 1rkq Escherichia coli Undefined 1 0 2.5 ± 1.3 79 ± 9 -4.1
3.2.02.02. T-2-conotoxin MrIA 2ew4 Conus marmoreus Secreted 1 0 2.5 ± 1.5 81 ± 19 -3.0
2.2.34.02. omega-Agatoxin 1agg Agelenopsis aperta Secreted 1 0 2.5 ± 1.4 57 ± 17 -5.0
3.1.20.01. Alpha-conotoxin EIVA 1pqr Conus ermineus Secreted 1 0 2.5 ± 1.3 14 ± 14 -3.4
2.2.20.01. Proto-oncogene vav, complex with Ras-related C3 botulinum toxin substrate 1 3bji Homo sapiens Eukaryo. plasma 2 0 2.5 ± 2.2 72 ± 14 -3.4
3.1.15.01. Curvacin-A 2a2b Lactobacillus curvatus Secreted 1 0 2.5 ± 1.3 34 ± 18 -6.7
3.1.03.06. 12 kDa heat shock protein 4axp Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.5 ± 0.1 74 ± 0 -5.5
2.4.16.04. Defensin-like protein 2 2n2r Raphanus sativus Secreted 1 0 2.5 ± 1.7 31 ± 24 -4.2
1.2.43.02. E1 envelope glycoprotein 3n41 Chikungunya virus Viral 1 0 2.5 ± 2.9 71 ± 7 -5.8
2.4.33.01. 72 kDa type IV collagenase, complex with inhibitor-2 1gxd Homo sapiens Eukaryo. plasma 2 0 2.5 ± 1.1 77 ± 4 -5.4
2.2.16.01. Lipoprotein LprG 3mh9 Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 2.5 ± 2.7 47 ± 10 -3.0
2.2.20.01. FYVE, RhoGEF and PH domain-containing protein 6 1wgq Mus musculus Eukaryo. plasma 1 0 2.5 ± 1.8 68 ± 17 -3.2
2.1.01.01. Snake phospholipase A2 homolog bothropstoxin-1, group II 3i03 Bothrops jararacussu Secreted 1 0 2.5 ± 0.5 76 ± 5 -10.6
2.4.13.01. Oxysterol-binding protein homolog 4 (KES1), N-terminal helix removed 1zi7 Saccharomyces cerevisiae Golgi 1 0 2.5 ± 0.5 75 ± 8 -6.9
2.2.27.01. C1 domain of unc-13 homolog A 1y8f Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 1.9 16 ± 17 -2.9
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 1 2xar Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 1.6 69 ± 7 -6.1
2.4.16.03. Potassium channel toxin alpha-KTx 3.1 3odv Androctonus mauretanicus mauretanicus (Scorpion) Secreted 1 0 2.6 ± 0.9 84 ± 5 -5.1
2.1.01.01. Snake phospholipase A2, group II, neutral 1bjj Agkistrodon halys pallas Secreted 1 0 2.6 ± 0.7 86 ± 5 -8.4
2.3.06.01. Acetylcholinesterase 5x61 Anopheles gambiae (African malaria mosquito) Eukaryo. plasma 1 0 2.6 ± 1.5 37 ± 4 -4.0
2.4.16.03. Potassium channel toxin alpha-KTx 4.2 6atl Tityus serrulatus Secreted 1 0 2.6 ± 1.6 66 ± 16 -3.4
3.1.13.01. Adrenomedullin 2l7s Homo sapiens Secreted 1 0 2.6 ± 0.7 90 ± 5 -6.7
2.2.09.01. Kelch-like protein 7 3ii7 Homo sapiens Undefined 1 0 2.6 ± 1.8 90 ± 16 -6.5
2.2.06.02. Prostaglandin-H2 D-isomerase, apo form 4ors Homo sapiens Endoplasm. reticulum 1 0 2.6 ± 0.8 71 ± 7 -3.7
2.3.16.01. Shikimate kinase 1e6c Erwinia chrysanthemi Bact. Gram-neg inner 2 0 2.6 ± 1.8 90 ± 12 -5.8
2.3.25.01. Acyloxyacyl hydrolase, structure 1 5w7c Homo sapiens Secreted 2 0 2.6 ± 0.8 83 ± 5 -5.2
2.2.52.01. Allene oxide cyclase 2 2brj Arabidopsis thaliana Chloroplast inner 3 0 2.6 ± 0.5 88 ± 5 -9.7
2.2.39.01. Cardiotoxin-A1 (cytotoxin 1) 2cdx Naja atra Secreted 1 0 2.6 ± 1.4 85 ± 17 -6.9
1.1.71.01. Legionalla phosphoinositide phosphatase, SidP 4jza Legionella pneumophila Vacuole 1 0 2.6 ± 1.7 57 ± 7 -5.6
2.3.16.07. GTP-binding protein Rheb 1xtq Homo sapiens Eukaryo. plasma 1 0 2.6 ± 0.6 76 ± 20 -5.1
1.1.26.07. STAS domain of sulfate permease 4dgf Wolinella succinogenes Bact. Gram-neg inner 1 0 2.6 ± 0.5 51 ± 2 -7.0
3.2.05.01. Sviceucin 2ls1 Streptomyces sviceus Secreted 1 0 2.6 ± 1.3 78 ± 5 -7.0
2.4.16.04. Defensin-like protein 32 2mz0 Arabidopsis thaliana Secreted 1 0 2.6 ± 1.4 19 ± 8 -3.4
2.3.06.12. Gibberellin receptor GID1A 2zsh Arabidopsis thaliana Nuclear inner 1 0 2.6 ± 1.2 89 ± 6 -5.0
2.4.06.03. S-norcoclaurine synthase 2vq5 Thalictrum flavum (Yellow meadow rue) Undefined 4 0 2.6 ± 0.3 90 ± 0 -7.0
2.2.06.02. Retinoid-binding protein 7 1lpj Homo sapiens Eukaryo. plasma 1 0 2.6 ± 1.1 44 ± 13 -6.0
2.2.12.04. AP-2 complex 2vj0 Rattus norvegicus Vesicle 1 0 2.6 ± 2.0 80 ± 11 -4.8
2.1.01.01. Snake phospholipase A2, group I 1ozy Micropechis ikaheka Secreted 1 0 2.6 ± 1.0 85 ± 5 -9.0
2.2.34.10. Imperatoxin-A 1ie6 Pandinus imperator (Emperor scorpion) Secreted 1 0 2.6 ± 0.8 55 ± 13 -3.1
2.1.10.01. Accelerated-cell-death 11 apo-protein 4nt1 Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 2.0 85 ± 7 -5.4
2.1.30.01. Membrane-integrating protein mistic, mstX 1ygm Bacillus subtilis Bact. Gram-pos plas. 1 0 2.6 ± 1.8 31 ± 6 -5.2
2.1.01.01. Snake phospholipase A2 natratoxin, group I 2osh Naja atra Secreted 1 0 2.6 ± 1.6 83 ± 11 -6.1
3.1.20.01. Alpha-conotoxin PIA 1zlc Conus purpurascens (Purple cone) Secreted 1 0 2.6 ± 1.3 59 ± 16 -4.3
1.2.44.01. Amyloid beta A4 protein (peptide 696-706) 1qcm Homo sapiens Eukaryo. plasma 1 0 2.6 ± 1.5 78 ± 17 -2.9
2.1.21.01. Influenza virus matrix protein M1, structure 1 1aa7 Influenza virus Viral 2 0 2.6 ± 0.8 89 ± 4 -5.6
2.1.08.01. Cytochrome c551 1cor Pseudomonas stutzeri Bact. Gram-neg inner 1 0 2.6 ± 1.1 73 ± 12 -6.1
3.2.05.02. Microcin J25, redesigned, version 2 2mmw Designed proteins Undefined 1 0 2.6 ± 3.5 90 ± 4 -3.7
2.1.01.01. Phospholipase A2 2not Notechis scutatus scutatus (Mainland tiger snake) Secreted 1 0 2.6 ± 1.5 73 ± 8 -3.9
3.2.01.07. Chignolin 5awl Designed proteins Undefined 1 0 2.6 ± 2.1 77 ± 28 -2.8
2.1.01.01. Snake phospholipase A2, acidic 2, group I 1p7o Micropechis ikaheka Secreted 1 0 2.6 ± 0.5 90 ± 2 -9.4
2.1.60.03. Natrin-1 1xx5 Naja atra Secreted 1 0 2.6 ± 2.4 60 ± 49 -5.2
2.4.16.03. Chlorotoxin 6atw Leiurus quinquestriatus quinquestriatus Secreted 1 0 2.6 ± 2.0 58 ± 6 -5.4
2.4.20.02. Arylamine N-acetyltransferase 1w5r Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 2.6 ± 0.5 82 ± 6 -6.2
2.2.34.02. U1-theraphotoxin-Hh1a 1i25 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.6 ± 0.2 79 ± 1 -5.1
2.2.39.01. Toxin B 1txa Ophiophagus hannah Secreted 1 0 2.6 ± 1.5 51 ± 16 -5.6
1.2.42.01. Acid sphingomyelinase-like phosphodiesterase 3a 5ebe Homo sapiens Secreted 1 0 2.6 ± 0.6 38 ± 1 -7.0
2.2.45.01. Pertactin autotransporter 1dab Bordetella pertussis Bact. Gram-neg outer 1 0 2.6 ± 1.1 73 ± 6 -5.9
1.2.50.01. Fragaceatoxin C, monomer 3lim Actinia fragacea (Strawberry anemone) Secreted 1 0 2.6 ± 0.8 46 ± 15 -5.0
1.2.43.02. E1 envelope glycoprotein 1rer Semiliki forest virus Viral 3 0 2.6 ± 2.0 38 ± 5 -6.5
2.4.16.04. Flower-specific gamma-thionin-like protein 4uj0 Solanum lycopersicum Secreted 1 0 2.6 ± 0.9 19 ± 5 -4.8
2.2.11.01. Protein kinase C beta 3pfq Rattus norvegicus Eukaryo. plasma 1 0 2.6 ± 0.9 45 ± 5 -3.4
1.2.17.01. SNARE complex with synaptotagmin1 2n1t Rattus norvegicus Eukaryo. plasma 5 0 2.6 ± 2.9 42 ± 16 -4.6
3.1.02.07. Sodium/hydrogen exchanger 1, TM helices 2kbv Homo sapiens Eukaryo. plasma 1 0 2.7 ± 6.9 74 ± 4 -4.9
2.2.12.01. Lymphocyte antigen 96, structure 2 4g8a Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.3 67 ± 6 -3.8
2.3.11.01. Ferrochelatase, conformation 1 1hrk Homo sapiens Mitochon. inner 2 0 2.7 ± 0.1 90 ± 0 -9.9
2.3.06.06. Triacylglycerol lipase, closed (inactive) state 3tgl Rhizomucor miehei Secreted 1 0 2.7 ± 1.1 39 ± 7 -5.8
2.1.18.01. Annexin XII 1dm5 Hydra vulgaris Eukaryo. plasma 3 0 2.7 ± 1.0 90 ± 7 -10.2
2.2.27.01. C1 domanin of SH3 and cysteine-rich domain-containing protein 3 2db6 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 0.1 75 ± 0 -4.8
2.2.34.02. Huwentoxin-1 1qk6 Haplopelma hainanum (Chinese bird spider) Secreted 1 0 2.7 ± 1.5 88 ± 11 -5.1
2.2.41.01. Beta-defensin 3 1kj6 Homo sapiens Secreted 1 0 2.7 ± 1.3 18 ± 18 -5.1
2.2.22.01. Hydrophobin NC2, structure 2 4bwh Neurospora crassa Secreted 1 0 2.7 ± 3.1 85 ± 29 -4.5
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4 3b7y Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.5 9 ± 6 -4.1
2.2.20.01. Son of sevenless homolog 1 (two domains) 1dbh Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.8 28 ± 19 -4.2
2.2.20.01. Ras-specific guanine nucleotide-releasing factor 2dtc Mus musculus Eukaryo. plasma 1 0 2.7 ± 0.4 64 ± 9 -6.3
2.1.64.01. Envelope glycoprotein, ligand-binding domain 1 5e7x Talaromyces marneffei Eukaryo. plasma 1 0 2.7 ± 2.2 55 ± 13 -4.4
1.2.41.01. Acyl-CoA-binding protein 2cb8 Homo sapiens Peroxisome 1 0 2.7 ± 2.0 74 ± 29 -5.2
2.2.14.02. SUN domain-containing protein 2 3unp Homo sapiens Nuclear outer 3 0 2.7 ± 0.1 20 ± 0 -5.3
2.3.09.01. Cytidylyltransferase 3hl4 Rattus norvegicus Eukaryo. plasma 2 0 2.7 ± 4.0 74 ± 8 -3.2
3.1.20.01. alpha-conotoxin MII 1mii Conus magus Secreted 1 0 2.7 ± 1.8 45 ± 19 -4.2
2.1.08.01. Cytochrome c552 1a8c Nitrosomonas europaea Bact. Gram-neg inner 1 0 2.7 ± 1.0 80 ± 11 -4.7
2.4.16.05. Plectasin 3e7r Pseudoplectania nigrella (Ebony cup) Secreted 1 0 2.7 ± 2.3 53 ± 17 -4.0
3.1.02.02. S4-3 voltage sensor peptide of calcium channel subunit alpha-1B (1242-1269) 2lcm Homo sapiens Eukaryo. plasma 1 0 2.7 ± 3.2 68 ± 6 -3.9
3.2.01.07. Transthyretin-derived peptide 5hpp Designed proteins Undefined 1 0 2.7 ± 1.6 83 ± 6 -5.2
2.4.06.05. Thermoacidophile-specific fatty acid carrier 3w9k Sulfolobus tokodaii Archaebac. 1 0 2.7 ± 1.4 47 ± 4 -7.1
2.3.06.06. Mono- and diacylglycerol lipase 5ch8 Penicillium cyclopium Secreted 1 0 2.7 ± 0.3 9 ± 7 -4.2
2.2.34.11. Kalata-B7 2jwm Oldenlandia affinis Secreted 1 0 2.7 ± 2.2 86 ± 28 -4.8
2.1.01.01. Ammodytin L1 isoform 3ux7 Vipera ammodytes meridionalis Secreted 1 0 2.7 ± 0.3 82 ± 1 -13.2
2.2.06.02. Myelin P2 protein 1pmp Bos taurus Eukaryo. plasma 1 0 2.7 ± 1.3 61 ± 13 -6.1
2.2.20.01. Rac-alpha serine/threonine kinase 1unq Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.0 67 ± 18 -3.9
2.4.07.01. PX domain of sorting nexin-14 4bgj Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 72 ± 22 -4.3
2.1.18.01. Annexin III 1axn Homo sapiens Eukaryo. plasma 1 0 2.7 ± 0.8 77 ± 11 -5.7
2.1.54.01. Programmed cell death protein 10 3ajm Homo sapiens Golgi 2 0 2.7 ± 0.4 86 ± 7 -5.8
2.2.39.02. Mambalgin-2 2mfa Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 2.7 ± 2.5 76 ± 5 -6.4
2.2.05.01. Azurin 1xb8 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 2.7 ± 0.6 47 ± 4 -5.2
2.1.42.01. Lactococcin-A immunity protein 5lfi Lactococcus lactis Secreted 1 0 2.7 ± 1.4 40 ± 9 -4.8
2.4.40.01. IpgB2 protein 3lxr Shigella flexneri Bact. Gram-neg inner 2 0 2.7 ± 0.4 75 ± 2 -6.7
2.1.18.01. Annexin A2 4x9p Bos taurus Vesicle 1 0 2.7 ± 2.4 81 ± 12 -3.5
1.2.51.01. Alkaline sphingomyelinase 5udy Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.3 84 ± 10 -4.5
2.3.06.02. Antigen 85c, conformation 4 5vns Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 2.7 ± 1.2 33 ± 2 -8.4
2.1.41.01. Phosphatidylinositol 3-kinase catalytic subunit type 3 3ls8 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 75 ± 9 -4.7
3.2.01.01. Arenicin-2, dimer 2l8x Arenicola marina Secreted 2 0 2.7 ± 1.1 87 ± 4 -4.0
1.2.03.09. Programmed cell death protein 1 3sbw Mus musculus Eukaryo. plasma 1 0 2.7 ± 0.9 89 ± 4 -5.9
2.2.10.01. High potential iron protein 1hpi Ectothiorhodospira vacuolata Bact. Gram-neg inner 1 0 2.7 ± 1.0 89 ± 12 -4.4
3.2.08.01. Peptide 35-42, alternate polymorph II 2y3l Homo sapiens Secreted 4 0 2.7 ± 1.4 78 ± 8 -6.0
2.2.45.02. Pectate lyase A 1pe9 Erwinia chrysanthemi Secreted 1 0 2.7 ± 0.4 81 ± 3 -6.4
2.1.29.01. Apolipoprotein A-I 2lem Mus musculus Secreted 1 0 2.7 ± 1.7 79 ± 2 -4.3
3.4.12.02. Thiostrepton, epimer form 2l2y Streptomyces azureus Secreted 1 0 2.7 ± 2.9 29 ± 9 -5.3
2.1.01.01. Snake phospholipase A2 RV-7, group II 1oqs Daboia russellii siamensis Secreted 1 0 2.7 ± 1.1 87 ± 8 -7.9
2.3.01.07. Chitinase A 1nh6 Serratia marcescens Secreted 1 0 2.7 ± 1.3 80 ± 5 -6.1
2.1.29.02. Apolipoprotein A-II 2ou1 Homo sapiens Secreted 2 0 2.7 ± 1.2 87 ± 2 -17.7
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 2 2w62 Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.7 ± 0.5 90 ± 1 -6.1
3.1.04.03. Viral protein R, peptide 13-33, different strain 1fi0 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 2.7 ± 1.2 88 ± 8 -8.6
2.4.50.01. Matrix protein, Indiana virus 1lg7 Vesicular stomatitis virus Viral 1 0 2.7 ± 0.4 82 ± 2 -7.3
2.4.04.01. Beta-hemolysin 3i48 Staphylococcus aureus Secreted 1 0 2.8 ± 0.8 57 ± 5 -5.1
2.3.06.02. Antigen 85a 1sfr Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 2.8 ± 0.8 27 ± 9 -7.5
2.1.03.01. Alpha-toxin 1olp Clostridium absonum Secreted 1 0 2.8 ± 1.8 62 ± 11 -6.1
2.2.11.01. Synaptotagmin-7 2d8k Homo sapiens Vesicle 1 0 2.8 ± 1.3 27 ± 16 -6.6
3.1.20.01. Alpha-conotoxin S1 1qmw Conus striatus Secreted 1 0 2.8 ± 2.6 43 ± 17 -2.5
3.1.08.01. Antifreeze protein A 1wfb Pseudopleuronectes americanus Secreted 1 0 2.8 ± 1.0 88 ± 1 -10.1
2.1.01.01. Phospholipase A2 homolog, taipoxin beta chain 3vbz Oxyuranus scutellatus scutellatus Secreted 1 0 2.8 ± 0.7 87 ± 2 -7.7
2.1.33.01. DrrA protein, PtdIns(4) binding domain, complex with PtdIns(4) 4mxp Legionella pneumophila Vacuole 1 0 2.8 ± 2.6 59 ± 12 -4.5
2.2.11.01. Synaptotagmin 1, C2A domain 5t0r Mus musculus Vesicle 1 0 2.8 ± 0.8 22 ± 14 -4.2
2.2.34.07. Asteropsin A 3q8j Asteropus sp. Secreted 1 0 2.8 ± 1.7 75 ± 15 -3.0
2.2.14.01. Lactadherin 3bn6 Bos taurus Secreted 1 0 2.8 ± 0.5 11 ± 4 -7.2
2.2.35.01. Streptolysin O 4hsc Streptococcus pyogenes Secreted 1 0 2.8 ± 3.5 15 ± 27 -5.1
2.4.51.01. Heme acquisition protein HasA, apoprotein 1ybj Serratia marcescens Secreted 1 0 2.8 ± 2.4 33 ± 9 -3.9
2.2.35.01. Anthrolysin O 3cqf Bacillus anthracis Secreted 1 0 2.8 ± 1.0 75 ± 1 -5.8
2.3.28.01. Aldo-keto reductase family 1 member C1 1qwk Caenorhabditis elegans Undefined 1 0 2.8 ± 1.0 66 ± 3 -6.3
2.4.43.01. Cell wall anchor protein of the T6SS system 4b62 Pseudomonas aeruginosa Bact. Gram-neg outer 1 0 2.8 ± 2.5 46 ± 36 -4.6
2.1.01.01. Myotoxin II 1y4l Bothrops asper Secreted 1 0 2.8 ± 0.8 76 ± 7 -10.3
2.2.20.01. Rho guanine nucleotide exchange factor 9 complex 2dfk Rattus norvegicus Eukaryo. plasma 2 0 2.8 ± 2.7 69 ± 3 -5.0
3.1.11.02. Glucagon-like peptide 1, with extracellular GPCR domain 3iol Homo sapiens Secreted 2 0 2.8 ± 4.0 70 ± 1 -6.7
2.3.28.01. Aldo-keto reductase family 1 member C21 3fjn Mus musculus Undefined 1 0 2.8 ± 1.0 56 ± 3 -5.2
2.2.41.01. Beta-defensin 8 1e4r Mus musculus Secreted 1 0 2.8 ± 1.1 74 ± 19 -5.5
2.2.12.02. Rho GDP-dissociation inhibitor 2, complex with G-protein RAC2 1ds6 Homo sapiens Eukaryo. plasma 2 0 2.8 ± 1.0 82 ± 6 -5.5
2.2.38.01. Colicin E3 1jch Escherichia coli Secreted 4 0 2.8 ± 0.3 89 ± 5 -8.8
2.2.05.01. Plastocyanin 1b3i Prochlorothrix hollandica Thylakoid 1 0 2.8 ± 1.4 43 ± 18 -4.4
2.2.39.01. alpha-Cobratoxin 1ctx Naja kaouthia Secreted 1 0 2.8 ± 1.7 29 ± 18 -4.6
2.2.34.02. M-theraphotoxin-Gr1a 1lu8 Grammostola rosea (Chilean rose tarantula) Secreted 1 0 2.8 ± 0.9 69 ± 7 -7.2
2.2.34.01. Omega conotoxin TxVII 1f3k Conus textile Secreted 1 0 2.8 ± 1.4 57 ± 18 -4.5
2.4.07.01. NADPH oxidase organizer 1, PX domain 2l73 Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.9 72 ± 13 -5.1
2.4.16.04. Defensin 2 (PDF1) 2gl1 Vigna radiata (Mung bean) Secreted 1 0 2.8 ± 0.6 6 ± 4 -5.7
2.3.06.12. Carboxylesterase (EstA) 1jji Archaeoglobus fulgidus Archaebac. 1 0 2.8 ± 1.0 56 ± 22 -4.8
2.1.01.01. Snake phospholipase A2, group II 1jlt Vipera ammodytes meridionalis Secreted 1 0 2.8 ± 1.0 89 ± 7 -8.7
2.2.02.01. Exfoliative toxin B 1qtf Staphylococcus aureus Secreted 1 0 2.8 ± 1.9 81 ± 11 -5.8
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 1 2q9f Homo sapiens Endoplasm. reticulum 1 0 2.8 ± 1.0 86 ± 7 -5.8
1.2.53.01. Squalene synthase, conformation 2 3wcf Homo sapiens Endoplasm. reticulum 1 0 2.8 ± 0.8 87 ± 3 -7.0
2.4.20.02. Arylamine N-acetyltransferase 1w4t Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 2.8 ± 0.4 82 ± 1 -5.8
2.4.03.01. Tubby protein, ligand-free 1c8z Mus musculus Eukaryo. plasma 1 0 2.8 ± 0.9 89 ± 13 -5.8
2.4.16.01. Beta-mammal toxin Cn2 2yc1 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.8 ± 1.1 68 ± 9 -3.8
3.4.02.03. Bovicin HJ50 2m8v Streptococcus equinus Secreted 1 0 2.8 ± 1.0 71 ± 8 -4.0
2.1.18.01. Annexin VI 1m9i Homo sapiens Eukaryo. plasma 1 0 2.8 ± 0.3 82 ± 0 -8.5
2.1.01.01. Acidic phospholipase A2 5 4rfp Trimeresurus stejnegeri Secreted 1 0 2.8 ± 0.3 81 ± 3 -7.1
2.3.06.17. Phosphatidylcholine-sterol acyltransferase, structure 3 5bv7 Homo sapiens Secreted 1 0 2.8 ± 3.1 76 ± 15 -6.1
1.2.52.01. Cytochrome c-type biogenesis protein CcmE 1sr3 Escherichia coli Bact. Gram-neg inner 1 0 2.8 ± 2.7 59 ± 6 -2.2
1.2.03.02. Hepatitis A virus cellular receptor 2 homolog 3kaa Mus musculus Eukaryo. plasma 1 0 2.8 ± 2.0 55 ± 16 -5.5
2.1.24.01. NK-lysin 1nkl Sus scrofa Secreted 1 0 2.8 ± 1.5 37 ± 12 -5.4
2.2.12.02. Rho GDP-dissociation inhibitor 1 1qvy Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.7 53 ± 19 -5.1
2.1.03.01. Phospholipase C 1p6d Bacillus cereus Secreted 1 0 2.8 ± 1.0 52 ± 6 -8.4
2.1.01.01. Phospholipase A2 BnSP-7 1pa0 Bothrops neuwiedi pauloensis Secreted 1 0 2.8 ± 1.0 78 ± 10 -6.9
3.2.05.02. Astexin-4 2n6u Asticcacaulis excentricus Secreted 1 0 2.8 ± 1.1 41 ± 21 -3.8
1.2.01.01. Macrophage colony-stimulating factor 1 receptor 3bea Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.5 54 ± 19 -4.2
3.2.01.06. Lactoferricin B, peptide 38-49 1y58 Bos taurus Secreted 1 0 2.9 ± 1.4 86 ± 18 -3.7
3.1.02.16. Peptide 211-263 of YscU protein 2ml9 Yersinia pseudotuberculosis Bact. Gram-neg inner 1 0 2.9 ± 1.8 82 ± 5 -6.6
2.2.35.01. Pneumolysin, structure 6 5aof Streptococcus pneumoniae Secreted 1 0 2.9 ± 2.4 33 ± 9 -5.7
2.3.14.01. Yeast Sec14 Homolog Sfh1 (YKL091C) 3b7n Saccharomyces cerevisiae Nuclear outer 1 0 2.9 ± 1.5 65 ± 18 -5.8
3.1.02.02. S4-S5 linker peptide (532-551) of HERG K+ channel 2le7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.4 69 ± 9 -5.0
2.4.16.01. Beta-toxin CsEI 1b3c Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.9 ± 1.2 70 ± 7 -3.9
2.2.41.01. Alpha-defensin cryptdin-4 1tv0 Mus musculus Secreted 1 0 2.9 ± 1.4 67 ± 13 -4.5
2.2.34.01. Omega conotoxin SO3 1fyg Conus striatus Secreted 1 0 2.9 ± 1.1 76 ± 18 -3.5
1.2.19.01. Mitochondrial import receptor subunit TOM20, 51-145, with presequence peptide 1om2 Rattus norvegicus Mitochon. outer 2 0 2.9 ± 2.7 76 ± 7 -4.8
2.2.06.02. Intestinal fatty acid binding protein, structure 1 1kzw Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.3 61 ± 12 -4.1
2.3.06.12. Carboxylesterase 3wj2 Thermoplasma acidophilum Secreted 1 0 2.9 ± 1.9 81 ± 9 -5.1
2.3.16.06. ADP-ribosylation factor 1 (ARF1) 2k5u Saccharomyces cerevisiae Golgi 1 0 2.9 ± 1.6 24 ± 18 -5.5
3.2.05.02. Caulosegnin I 2lx6 Caulobacter segnis Secreted 1 0 2.9 ± 0.8 15 ± 5 -6.0
2.2.42.01. Matrix protein 2vqp Human respiratory syncytial virus Eukaryo. plasma 1 0 2.9 ± 1.1 86 ± 10 -6.1
2.2.11.01. Protein kinase C epsilon 1gmi Rattus rattus Eukaryo. plasma 1 0 2.9 ± 1.2 46 ± 15 -5.9
2.2.34.02. Mu-theraphotoxin-Pn3a 5t4r Theraphosidae Secreted 1 0 2.9 ± 0.8 87 ± 5 -4.5
3.1.35.01. Cn-AMP1 peptide 2n0v Cocos nucifera Secreted 1 0 2.9 ± 1.3 73 ± 18 -2.3
1.2.43.06. Outer capsid protein VP4, trimer 2b4i Rotavirus A Viral 3 0 2.9 ± 0.3 2 ± 0 -11.7
1.3.25.01. Gamma-hemolysin, heterodimer of components A and B 2qk7 Staphylococcus aureus Secreted 2 0 2.9 ± 2.0 83 ± 11 -5.7
3.1.14.01. Eledoisin 1mxq Eledone cirrhosa (Curled octopus) Secreted 1 0 2.9 ± 1.7 59 ± 19 -5.0
2.2.07.01. Polyisoprenoid-binding protein 1wub Thermus thermophilus Bact. Gram-neg inner 1 0 2.9 ± 1.9 42 ± 13 -4.4
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 2 3c6e Dengue virus Viral 1 0 2.9 ± 2.7 42 ± 5 -3.6
2.1.03.01. Alpha-toxin (PHLC1_CLOPE), open state 1ca1 Clostridium perfringens Secreted 1 0 2.9 ± 1.0 89 ± 4 -9.3
2.4.04.01. Sphingomyelin phosphodiesterase 3 5uvg Homo sapiens Golgi 1 0 2.9 ± 1.6 59 ± 13 -5.1
2.4.16.02. Nasonin 2koz Nasonia vitripennis (Parasitic wasp) Secreted 1 0 2.9 ± 0.9 68 ± 7 -4.6
2.2.34.02. Delta-amaurobitoxin-Pl1a 1v90 Pireneitega luctuosa (Tangled nest spider) Secreted 1 0 2.9 ± 0.7 26 ± 14 -4.0
2.2.11.01. Rabphilin-3A, C2A domain 2chd Rattus norvegicus Eukaryo. plasma 1 0 2.9 ± 1.6 57 ± 19 -2.7
3.2.06.01. Paralytic peptide 2 1v28 Manduca sexta Secreted 1 0 2.9 ± 1.4 90 ± 16 -4.9
3.1.11.01. Neuropeptide F 1k8v Moniezia expansa (Sheep tapeworm) Secreted 1 0 2.9 ± 1.1 68 ± 9 -7.0
3.4.02.06. Epilancin 15X 1w9n Staphylococcus epidermidis Secreted 1 0 2.9 ± 1.0 72 ± 7 -5.0
3.2.06.01. Growth-blocking peptide 2djc Spodoptera litura Secreted 1 0 2.9 ± 2.0 19 ± 14 -3.1
1.2.04.01. Integrin alpha-IIb, cytoplasmic domain 1s4w Homo sapiens Eukaryo. plasma 1 0 2.9 ± 0.3 69 ± 3 -9.1
2.2.06.02. Fatty acid-binding protein homolog 1 1o8v Echinococcus granulosus Eukaryo. plasma 1 0 2.9 ± 1.0 48 ± 15 -5.8
1.2.05.02. Internalin C 1xeu Listeria monocytogenes Bact. Gram-pos plas. 1 0 2.9 ± 1.3 81 ± 0 -4.1
2.2.06.02. Retinol-binding protein 2 2rcq Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 55 ± 6 -5.5
2.4.11.01. beta-Purothionin 1bhp Triticum aestivum Secreted 1 0 2.9 ± 2.0 56 ± 19 -4.8
2.1.29.05. Apolipoprotein C-III 2jq3 Homo sapiens Secreted 1 0 2.9 ± 1.4 85 ± 0 -5.6
2.2.21.02. Fibroblast growth factor 19 1pwa Homo sapiens Secreted 1 0 2.9 ± 1.5 48 ± 21 -4.7
2.4.51.01. Heme acquisition protein HasA, alternative position of heme 3mol Pseudomonas aeruginosa Secreted 1 0 2.9 ± 0.6 40 ± 5 -5.8
2.4.33.01. 72 kDa type IV collagenase, full-length 1ck7 Homo sapiens