PDB ID or protein name

All proteins in OPM (3622 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
1.1.10.03. ABC transporter related protein 4mrs Novosphingobium aromaticivorans Bact. Gram-neg inner 2 12 32.0 ± 1.0 0 ± 0 -92.5
1.1.15.02. Proton-gated ion channel, inactive conformation 1 2vl0 Erwinia chrysanthemi Bact. Gram-neg inner 5 20 31.8 ± 1.3 0 ± 0 -107.6
1.1.16.01. Glutamate receptor ionotropic, kainate 2 5kuf Rattus norvegicus Eukaryo. plasma 4 12 31.4 ± 0.6 0 ± 0 -81.8
1.1.17.01. Rh-like protein 3b9y Nitrosomonas europaea Bact. Gram-neg inner 3 33 29.8 ± 1.3 0 ± 0 -150.1
1.1.61.01. Microsomal prostaglandin E synthase 1, structure 2 4bpm Homo sapiens Endoplasm. reticulum 3 12 31.6 ± 1.4 0 ± 3 -87.5
1.1.10.05. ABC transporter ABCG2, structure 1 5nj3 Homo sapiens Eukaryo. plasma 2 12 31.0 ± 1.0 0 ± 0 -106.7
1.3.16.01. Osmoporin OMPC 3upg Salmonella typhimurium Bact. Gram-neg outer 3 48 23.4 ± 0.7 0 ± 0 -118.0
1.1.15.01. Gamma-aminobutyric acid receptor, GABA, chimaeric beta3-alpha5 5ojm Homo sapiens Eukaryo. plasma 5 20 31.0 ± 0.8 0 ± 0 -136.5
1.1.32.01. Proton glutamate symport protein, outward-facing state 2 2nww Pyrococcus horikoshii Archaebac. 3 36 30.6 ± 0.6 0 ± 0 -200.2
1.3.25.05. Lysenin, structure 1 5gaq Eisenia fetida Secreted 9 18 23.6 ± 0.8 0 ± 0 -68.7
1.1.15.02. Proton-gated ion channel, inactive conformation 2 3uq7 Erwinia chrysanthemi Bact. Gram-neg inner 5 20 32.0 ± 1.6 0 ± 1 -92.6
1.2.08.01. TYRO protein tyrosine kinase-binding protein, homotetramer 4wo1 Homo sapiens Eukaryo. plasma 4 4 41.8 ± 3.7 0 ± 2 -63.1
1.1.05.01. Polysulfide reductase, substrate-bound state 2vpx Thermus thermophilus Bact. Gram-neg inner 2 16 27.1 ± 1.1 0 ± 1 -103.3
1.1.05.02. Formate dehydrogenase 1kqf Escherichia coli Bact. Gram-neg inner 6 15 33.7 ± 1.1 0 ± 0 -141.9
1.3.16.01. OmpC porin 5fvn Enterobacter cloacae Bact. Gram-neg outer 3 48 23.2 ± 0.6 0 ± 0 -124.2
1.1.10.09. Macrolide export permease MacB 5gko Acinetobacter baumannii Bact. Gram-neg inner 2 8 30.2 ± 1.0 0 ± 0 -64.1
1.1.02.03. Photosystem II, Br-substituted 3a0b Thermosynechococcus vulcanus Thylakoid 34 72 31.8 ± 0.4 0 ± 0 -397.1
1.1.61.01. Microsomal prostaglandin E synthase 1, structure 3 4yl3 Homo sapiens Endoplasm. reticulum 3 12 29.8 ± 0.7 0 ± 0 -85.2
1.3.24.01. Outer membrane protein TolC 1ek9 Escherichia coli Bact. Gram-neg outer 3 12 24.6 ± 1.4 0 ± 2 -56.1
1.2.44.01. Amyloid beta A4 protein, 699-726, dimer, structure 2 2lz3 Homo sapiens Eukaryo. plasma 2 2 37.2 ± 1.8 0 ± 1 -26.9
1.1.12.11. NaK potassium channel 2ahy Bacillus cereus Bact. Gram-pos plas. 4 8 29.5 ± 0.7 0 ± 1 -105.7
1.1.12.14. TRPV1 ion channel 3j5p Rattus norvegicus Eukaryo. plasma 4 24 28.4 ± 0.7 0 ± 0 -213.2
1.1.89.01. Inner membrane protein YgaP 2mpn Escherichia coli Bact. Gram-neg inner 2 4 30.0 ± 1.5 0 ± 1 -29.6
1.1.12.03. High conductance calcium-activated potassium channel, structure 2 5tji Aplysia californica Eukaryo. plasma 4 28 31.4 ± 0.6 0 ± 0 -294.2
1.1.15.02. Proton-gated ion channel - human GLRA1 channel chimera 4x5t Gloeobacter violaceus Bact. Gram-neg inner 5 20 35.8 ± 0.1 0 ± 0 -107.4
1.1.16.01. Glutamate receptor 2, with TARP channel, structure 4 5vov Rattus norvegicus Eukaryo. plasma 8 20 31.4 ± 0.4 0 ± 0 -232.0
1.1.16.01. Glutamate receptor 2, with partial agonist, structure 6 4u4g Rattus norvegicus Eukaryo. plasma 4 12 33.0 ± 1.6 0 ± 0 -79.1
1.1.26.05. Arginine/agmatine antiporter (AdiC), outward-facing structure 2 5j4i Escherichia coli Bact. Gram-neg inner 2 24 32.8 ± 0.9 0 ± 0 -155.1
1.1.06.01. Cytochrome bc1, mitochondrial, structure 1 1l0l Bos taurus Mitochon. inner 12 26 30.0 ± 0.6 0 ± 0 -186.6
1.1.01.01. Cruxrhodopsin-3 4jr8 Haloarcula vallismortis Archaebac. 3 21 31.8 ± 1.2 0 ± 0 -130.4
1.1.15.02. Proton-gated ion channel, conformation 1 3tlw Gloeobacter violaceus Bact. Gram-neg inner 5 20 34.0 ± 1.6 0 ± 0 -190.3
1.3.11.03. Amyloid secretion protein FapF, structure 1 5o65 Pseudomonas sp. Bact. Gram-neg outer 3 36 25.0 ± 0.4 0 ± 0 -126.2
1.1.01.04. Smoothened homolog, dimer, structure 1 4jkv Homo sapiens Eukaryo. plasma 2 14 31.9 ± 1.2 0 ± 0 -98.5
1.1.26.04. L-carnitine/gamma-butyrobetaine antiporter 4m8j Proteus mirabilis Bact. Gram-neg inner 3 36 29.8 ± 0.8 0 ± 0 -220.2
1.1.01.02. Rhodopsin, active (metarhodopsin II), without transducin peptide 3pxo Bos taurus Eukaryo. plasma 2 14 31.8 ± 1.2 0 ± 0 -125.4
1.1.15.02. Proton-gated ion channel, inactive conformation 3 3rqw Erwinia chrysanthemi Bact. Gram-neg inner 5 20 29.8 ± 0.4 0 ± 0 -118.8
1.1.12.15. Ryanodine receptor 2, closed state 5go9 Sus scrofa Eukaryo. plasma 4 24 30.8 ± 0.3 0 ± 0 -188.1
1.1.26.05. Arginine/agmatine antiporter (AdiC), outward-facing structure 1 3h5m Escherichia coli Bact. Gram-neg inner 2 26 29.0 ± 0.8 0 ± 0 -128.9
1.1.12.04. Nucleotide-gated channel 1, HCN1, structure 2 5u6p Homo sapiens Eukaryo. plasma 4 26 31.8 ± 0.8 0 ± 0 -237.0
1.1.12.16. TRPML3 (Mucolipin-3) channel, structure 3 6ayg Homo sapiens Lysosome 4 24 31.0 ± 0.8 0 ± 0 -132.3
1.2.23.01. M2 proton channel of Influenza A, complex with amantadine 2kqt Influenza virus Viral 4 4 30.2 ± 1.3 0 ± 4 -59.6
1.1.01.01. Bacteriorhodopsin, K state, with lipids 1iw6 Halobacterium salinarum Archaebac. 3 21 30.0 ± 0.6 0 ± 0 -112.6
1.1.16.01. Glutamate receptor 2, with partial agonist, structure 1 4u1x Rattus norvegicus Eukaryo. plasma 4 12 29.8 ± 0.8 0 ± 0 -79.3
1.1.21.01. CorA magnesium transporter, complete loops, structure 2 3jcf Thermotoga maritima Bact. Gram-neg inner 5 10 31.6 ± 0.7 0 ± 0 -78.0
1.1.12.02. Potassium channel Kv1.2 - Kv2.1. chimera, inactivated state 5wie Rattus norvegicus Eukaryo. plasma 4 24 30.6 ± 0.4 0 ± 0 -245.0
1.1.10.01. Heme importer BhuUV, with BhuT protein 5b58 Burkholderia cepacia Bact. Gram-neg inner 2 20 29.0 ± 1.0 0 ± 0 -81.6
1.1.15.02. Proton-gated ion channel, inactive conformation 5 5lg3 Erwinia chrysanthemi Bact. Gram-neg inner 5 20 33.8 ± 1.1 0 ± 0 -108.7
1.1.10.01. ABC transporter BtuCD, symmetric structure 1l7v Escherichia coli Bact. Gram-neg inner 2 22 30.7 ± 1.1 0 ± 1 -121.0
1.1.10.03. Lipid flippase MsbA, closed state 3b5x Vibrio cholerae Bact. Gram-neg inner 2 12 30.2 ± 1.0 0 ± 0 -58.7
1.3.25.01. Alpha-hemolysin 7ahl Staphylococcus aureus Secreted 7 14 23.5 ± 0.9 0 ± 1 -49.3
1.1.12.14. TRPV1 with DkTx and RTX, in lipid nanodisc 5irx Rattus norvegicus Eukaryo. plasma 4 24 29.6 ± 0.5 0 ± 0 -190.8
1.3.16.02. Porin 2por Rhodobacter capsulatus Bact. Gram-neg outer 3 48 23.4 ± 0.6 0 ± 0 -114.8
1.1.50.01. Particulate methane monooxygenase 3chx Methylosinus trichosporium Bact. Gram-neg inner 10 30 29.8 ± 0.4 0 ± 0 -152.0
1.1.27.01. Ferrous-iron efflux pump fieF 3h90 Escherichia coli Bact. Gram-neg inner 2 12 29.6 ± 0.8 0 ± 2 -83.9
1.3.16.01. Porin OmpF 3nsg Salmonella enterica Bact. Gram-neg outer 3 48 23.6 ± 0.8 0 ± 0 -123.4
1.1.19.01. Mechanosensitive channel protein MscS 3t9n Thermoanaerobacter tengcongensis Bact. Gram-pos plas. 7 7 28.0 ± 0.7 0 ± 0 -131.5
1.2.11.01. Capsid protein G8P 1ifl Bacteriophage IKe Secreted 10 10 30.8 ± 0.8 0 ± 0 -93.6
1.1.10.05. ABC transporter ABCG2, structure 2 5njg Homo sapiens Eukaryo. plasma 2 12 31.0 ± 1.0 0 ± 0 -105.6
1.3.20.01. Fe-regulated protein B 4aip Neisseria meningitidis Bact. Gram-neg outer 3 66 23.4 ± 0.3 0 ± 0 -144.6
1.1.15.01. GLIC-GABAAR alpha1 chimera, structure 1 5osa Mus musculus Eukaryo. plasma 5 20 31.0 ± 0.6 0 ± 1 -121.7
1.3.16.01. Porin B (PorB), different strain 3wi4 Neisseria meningitidis Bact. Gram-neg outer 3 48 23.4 ± 0.6 0 ± 0 -112.6
1.1.12.11. NaK-NavSulP chimera channel 3vou Sulfitobacter sp. Bact. Gram-neg inner 4 8 30.4 ± 0.8 0 ± 0 -100.1
1.1.28.05. Hopanoid transporter HpnN, structure 1 5khn Burkholderia multivorans Bact. Gram-neg inner 2 24 27.8 ± 1.0 0 ± 0 -111.2
1.1.05.03. Respiratory Nitrate Reductase 1q16 Escherichia coli Bact. Gram-neg inner 2 10 30.1 ± 0.9 0 ± 0 -126.9
1.1.02.03. Photosystem II, monomeric form 3kzi Thermosynechococcus elongatus Thylakoid 16 36 31.8 ± 0.5 0 ± 0 -310.1
1.1.28.02. Efflux transporter CusA, apo-protein 3k07 Escherichia coli Bact. Gram-neg inner 3 33 27.4 ± 1.2 0 ± 0 -166.7
1.3.24.01. Multidrug Resistance (VceC) protein 1yc9 Vibrio cholerae Bact. Gram-neg outer 3 12 24.6 ± 1.0 0 ± 0 -62.2
1.1.12.14. TRPV1 ion channel, complex with DkTx and RTX toxins 3j5q Rattus norvegicus Eukaryo. plasma 4 24 30.0 ± 0.5 0 ± 0 -203.0
1.1.50.01. Particulate methane monooxygenase 4phz Methylocystis sp. Bact. Gram-neg inner 12 42 30.0 ± 0.9 0 ± 0 -200.6
1.1.15.01. Glutamate-gated chloride channel GluCl, with partial agonist 3rhw Caenorhabditis elegans Eukaryo. plasma 5 20 30.2 ± 0.7 0 ± 0 -107.9
1.1.36.01. CLC-K chloride channel, structure 1 5tqq Bos taurus Eukaryo. plasma 2 28 31.4 ± 0.4 0 ± 0 -126.9
1.1.14.01. Aquaporin Z2 3llq Agrobacterium tumefaciens Bact. Gram-neg inner 4 32 29.8 ± 0.6 0 ± 0 -134.5
3.1.07.02. Paramyxovirus sv5 fusion protein core 1svf Simian virus 5 Viral 6 0 8.4 ± 0.9 0 ± 11 -10.7
1.2.01.01. Vascular endothelial growth factor receptor 2 (759-795), homodimer 2 2meu Homo sapiens Eukaryo. plasma 2 2 32.0 ± 1.7 0 ± 2 -24.7
1.3.24.01. Outer membrane protein TolC, mutant, open conformation 1 2wmz Escherichia coli Bact. Gram-neg outer 3 12 24.4 ± 0.8 0 ± 0 -52.8
1.1.24.01. Bestrophin-1 4rdq Gallus gallus Eukaryo. plasma 4 16 30.8 ± 1.0 0 ± 0 -124.8
1.1.06.01. Cytochrome bc1, mitochondrial, with cytochrome c iso-1 3cx5 Saccharomyces cerevisiae Mitochon. inner 10 24 27.2 ± 0.6 0 ± 0 -173.9
1.1.10.03. Mitochondrial ABC transporter ABCB10, conformation 2 4ayw Homo sapiens Mitochon. inner 2 12 29.0 ± 0.8 0 ± 0 -65.8
1.1.21.01. CorA magnesium transporter, structure 3 2iub Thermotoga maritima Bact. Gram-neg inner 5 10 28.0 ± 1.2 0 ± 0 -65.7
1.3.26.01. Porin MspA 1uun Mycobacterium smegmatis Bact. Gram-pos cell wall 8 16 40.7 ± 2.1 0 ± 0 -71.0
1.1.26.01. Leucine transporter LeuT, outward-facing substrate-bound conformation 2a65 Aquifex aeolicus Bact. Gram-neg inner 2 28 29.8 ± 0.5 0 ± 0 -157.9
1.3.11.03. Amyloid secretion protein FapF, structure 2 5o67 Pseudomonas sp. Bact. Gram-neg outer 3 36 25.0 ± 0.6 0 ± 0 -123.7
1.1.12.14. TRPV2 channel 5hi9 Rattus norvegicus Eukaryo. plasma 4 24 30.2 ± 1.0 0 ± 0 -187.5
1.1.02.02. Photosystem I of cyanobacteria, virus-like, structure 1 4kt0 Synechocystis sp. Thylakoid 6 27 32.0 ± 0.7 0 ± 0 -235.3
1.1.28.01. Heavy metal cation tricomponent efflux pump, ZneA 4k0e Ralstonia metallidurans Bact. Gram-neg inner 3 36 28.0 ± 0.7 0 ± 0 -161.5
1.1.01.02. Squid rhodopsin, complex with 11-cis retinal, dimer 2z73 Todarodes pacificus Eukaryo. plasma 2 14 32.9 ± 1.0 0 ± 1 -143.3
1.1.26.08. Boron transporter 1 5l25 Arabidopsis thaliana Eukaryo. plasma 2 28 30.8 ± 0.5 0 ± 0 -109.6
1.1.12.15. Ryanodine receptor 2, open state 5goa Sus scrofa Eukaryo. plasma 4 24 30.8 ± 0.1 0 ± 0 -194.3
1.1.12.01. Potassium channel KcsA, open inactivated state 3f5w Streptomyces lividans Bact. Gram-pos plas. 4 8 29.2 ± 0.7 0 ± 0 -83.5
1.1.12.19. ATP-sensitive K+ channel SUR1/Kir6.2 5wua Mus musculus Eukaryo. plasma 8 76 31.0 ± 0.6 0 ± 0 -286.4
1.1.10.03. ATP-binding cassette, sub-family B, member 1 3wme Cyanidoschyzon merolae Eukaryo. plasma 2 12 35.0 ± 1.6 0 ± 0 -83.5
3.1.07.02. Envelope glycoprotein gp41 2x7r Human immunodeficiency virus type 1 Viral 3 0 5.5 ± 1.1 0 ± 10 -10.9
1.1.01.01. Bacteriorhodopsin, trimer, complex with annular lipids 2zzl Halobacterium salinarum Archaebac. 3 21 29.8 ± 0.6 0 ± 0 -119.0
1.1.12.09. Sodium channel NavMs, full-length 5hvx Magnetococcus marinus Bact. Gram-neg inner 4 24 29.0 ± 0.6 0 ± 0 -159.6
1.1.12.18. TrkH/TrkA potassium transport complex, structure 2 5but Bacillus subtilis Bact. Gram-pos plas. 2 16 32.0 ± 0.7 0 ± 0 -143.8
1.3.29.01. Bacterial amyloid secretion channel CsgG, structure 1 4q79 Escherichia coli Bact. Gram-neg outer 9 36 25.6 ± 0.6 0 ± 0 -82.4
1.1.12.14. Transient receptor potential cation channel A1, TRPA1 3j9p Homo sapiens Eukaryo. plasma 4 24 26.8 ± 0.3 0 ± 0 -121.0
1.1.12.15. Ryanodine receptor 1, closed structure 2 3j8h Oryctolagus cuniculus Endoplasm. reticulum 4 24 30.8 ± 0.0 0 ± 0 -190.3
1.1.12.18. Multi-ligand gated K(+) channel, TrkA, mutant 4gx0 Geobacter sulfurreducens Bact. Gram-neg inner 4 8 31.8 ± 1.3 0 ± 0 -109.5
1.1.13.02. ATP-gated P2X4 ion channel, closed state 3h9v Danio rerio Eukaryo. plasma 3 6 27.6 ± 1.3 0 ± 1 -61.3
1.1.08.01. F1F0 ATP synthase, F0 complex 4f4s Saccharomyces cerevisiae Mitochon. inner 10 20 38.4 ± 1.3 0 ± 0 -89.9
1.1.02.05. Light-harvesting complex LH2 1nkz Rhodopseudomonas acidophila Bact. Gram-neg inner 18 18 31.8 ± 0.6 0 ± 0 -193.5
1.1.12.14. TRPV2 channel 5an8 Oryctolagus cuniculus Eukaryo. plasma 4 24 31.8 ± 0.4 0 ± 0 -220.1
1.1.10.03. Antibacterial peptide transporter McjD, inward occluded state 5ofp Escherichia coli Bact. Gram-neg inner 2 12 31.4 ± 1.2 0 ± 0 -104.5
1.1.14.01. Aquaporin-0 2b6o Ovis aries Eukaryo. plasma 4 32 31.8 ± 1.4 0 ± 0 -143.3
1.1.12.14. TRPV1, in lipid nanodisc 5irz Rattus norvegicus Eukaryo. plasma 4 24 30.4 ± 0.7 0 ± 0 -208.9
1.3.16.02. Porin 3prn Rhodopseudomonas blastica Bact. Gram-neg outer 3 48 23.2 ± 0.5 0 ± 0 -127.6
1.1.02.03. PSII-LHCII supercomplex 5xnl Pisum sativum Thylakoid 58 0 29.0 ± 0.4 0 ± 0 -539.7
1.1.02.04. LH1-RC complex, P21 form 3wmo Thermochromatium tepidum Bact. Gram-neg inner 35 43 31.8 ± 0.1 0 ± 0 -234.8
1.1.19.01. Mechanosensitive channel protein MscS, open state 5aji Escherichia coli Bact. Gram-neg inner 7 21 29.8 ± 1.7 0 ± 0 -127.8
1.1.19.01. Mechanosensitive channel protein MscS, slightly different conf. 3udc Thermoanaerobacter tengcongensis Bact. Gram-pos plas. 7 7 32.2 ± 0.7 0 ± 0 -121.8
1.2.50.01. Fragaceatoxin C, transmembrane octamer 4tsy Actinia fragacea (Strawberry anemone) Secreted 8 8 29.8 ± 1.3 0 ± 0 -79.7
1.1.26.01. Leucine transporter LeuT, outward-facing, return state 5jae Aquifex aeolicus Bact. Gram-neg inner 2 24 29.0 ± 0.8 0 ± 0 -143.0
1.1.12.13. Potassium channel Kirbac3.1, open conformation 3zrs Magnetospirillum magnetotacticum Bact. Gram-neg inner 4 8 30.0 ± 1.1 0 ± 0 -85.9
1.3.16.01. Porin B (PorB), different strain, conformation 2 3wi5 Neisseria meningitidis Bact. Gram-neg outer 3 48 25.4 ± 0.9 0 ± 0 -117.2
1.1.14.01. Aquaporin-1, structure 2 4csk Homo sapiens Eukaryo. plasma 4 24 31.6 ± 0.8 0 ± 0 -152.1
1.1.15.02. Proton-gated ion channel, conformation 9 5j0z Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.2 ± 1.4 0 ± 0 -171.9
1.1.32.01. Proton/glutamate symporter, substrate-bound 5e9s Pyrococcus kodakaraensis Archaebac. 3 24 31.4 ± 0.6 0 ± 0 -197.9
1.1.28.05. Hopanoid transporter HpnN, structure 2 5khs Burkholderia multivorans Bact. Gram-neg inner 2 24 28.2 ± 0.8 0 ± 0 -100.7
1.3.12.01. Outer membrane phospholipase A, dimer 5dqx Salmonella enterica Bact. Gram-neg outer 2 24 23.4 ± 1.1 0 ± 0 -73.5
1.2.01.01. Epidermal growth factor receptor, erbB-1, homodimer (642-697) 2m20 Homo sapiens Eukaryo. plasma 2 2 34.0 ± 3.0 0 ± 3 -52.5
1.1.08.01. F1F0 ATP synthase, F0 complex 2xqu Arthrospira platensis Thylakoid 15 30 31.8 ± 0.8 0 ± 0 -129.7
1.1.28.02. Efflux transporter CusA, Cu(i) complex 3kss Escherichia coli Bact. Gram-neg inner 3 33 28.8 ± 0.5 0 ± 0 -147.7
1.3.24.01. Drug-Discharge Outer Membrane Protein, OprM 1wp1 Pseudomonas aeruginosa Bact. Gram-neg outer 3 12 24.7 ± 1.2 0 ± 0 -64.0
1.1.90.01. Phosphatidate cytidylyltransferase, conformation 2 4q2g Thermotoga maritima Bact. Gram-neg inner 2 18 26.8 ± 0.4 0 ± 2 -55.6
1.1.12.13. Kir3.1-prokaryotic Kir channel chimera 2qks Burkholderia xenovorans Bact. Gram-neg inner 4 8 30.5 ± 1.4 0 ± 1 -88.6
1.1.13.02. P2X purinoceptor, structure 1 5u1x Ailuropoda melanoleuca Eukaryo. plasma 3 6 30.2 ± 2.2 0 ± 1 -39.0
1.1.12.16. TRPML1 (Mucolipin-1) channel, closed 5wj5 Homo sapiens Lysosome 4 24 29.0 ± 0.8 0 ± 0 -211.4
1.1.64.01. Ca2+/H+ antiporter YfkE, different conformation 4kjs Bacillus subtilis Bact. Gram-pos plas. 3 33 31.2 ± 0.8 0 ± 0 -201.6
1.1.14.02. Formate transporter 3q7k Salmonella enterica Bact. Gram-neg inner 5 30 28.6 ± 0.0 0 ± 0 -148.8
1.1.32.01. Proton glutamate symport protein, inward-facing state 1 3kbc Pyrococcus horikoshii Archaebac. 3 30 28.1 ± 0.9 0 ± 1 -158.8
1.3.24.01. Outer membrane protein TolC, mutant, open conformation 2 2vde Escherichia coli Bact. Gram-neg outer 3 12 24.4 ± 1.2 0 ± 0 -57.4
1.1.32.01. Proton glutamate symport protein, inward-facing state 2 4p19 Pyrococcus horikoshii Archaebac. 3 30 30.6 ± 1.0 0 ± 0 -172.9
1.1.65.01. Concentrative nucleoside transporter, inward-facing state 5l26 Neisseria wadsworthii Bact. Gram-neg inner 3 24 29.0 ± 0.4 0 ± 0 -168.2
1.1.36.01. ClC chloride transporter 1ots Escherichia coli Bact. Gram-neg inner 2 28 29.7 ± 0.8 0 ± 0 -115.3
1.1.29.03. GDP-mannose transporter 1 5oge Saccharomyces cerevisiae Golgi 2 20 25.8 ± 0.2 0 ± 0 -122.5
1.1.36.01. ClC chloride transporter 3org Cyanidoschyzon merolae Eukaryo. plasma 2 28 28.7 ± 1.3 0 ± 2 -140.4
1.1.21.01. CorA magnesium transporter, structure 1 2bbj Thermotoga maritima Bact. Gram-neg inner 5 10 29.9 ± 1.0 0 ± 0 -80.8
1.1.115.01. MlaA protein, with OMPF (E. coli) 5nuo Klebsiella pneumoniae Bact. Gram-neg outer 6 54 23.4 ± 0.6 0 ± 0 -181.3
1.1.17.01. Ammonium transporter MEP2, structure 2 5ah3 Candida albicans Eukaryo. plasma 3 33 31.8 ± 0.7 0 ± 0 -157.0
1.1.14.01. Aquaglyceroporin 3c02 Plasmodium falciparum Eukaryo. plasma 4 32 30.4 ± 1.3 0 ± 0 -137.4
1.3.16.01. Osmoporin OMPC 2j1n Escherichia coli Bact. Gram-neg outer 3 48 25.1 ± 1.2 0 ± 2 -126.2
1.1.13.01. Acid-sensitive ion channel 1, with psalmotoxin 4fz1 Gallus gallus Eukaryo. plasma 3 6 31.8 ± 0.9 0 ± 0 -32.3
1.1.12.01. Potassium channel KscA, complex with charibdotoxin 2a9h Streptomyces lividans Bact. Gram-pos plas. 4 8 31.8 ± 1.4 0 ± 1 -105.1
1.1.12.19. ATP-sensitive K+ channel SUR1/Kir6.2, structure 2 5twv Rattus norvegicus Eukaryo. plasma 8 76 31.8 ± 0.4 0 ± 0 -311.7
1.1.66.01. K(+)-pumping pyrophosphatase, structure 3 5lzq Thermotoga maritima Bact. Gram-neg inner 2 32 31.0 ± 0.6 0 ± 0 -185.6
1.1.12.15. Ryanodine receptor 1, closed structure 3 5gkz Oryctolagus cuniculus Endoplasm. reticulum 4 24 30.8 ± 0.0 0 ± 0 -188.8
1.1.12.18. Multi-ligand gated K(+) channel, TrkA 4gx5 Geobacter sulfurreducens Bact. Gram-neg inner 4 8 31.6 ± 0.7 0 ± 0 -94.6
1.1.02.05. Light-harvesting complex LH3 1ijd Rhodopseudomonas acidophila Bact. Gram-neg inner 18 18 29.8 ± 0.7 0 ± 0 -174.6
1.1.28.02. Efflux pump membrane transporter CmeB, structure 2 5t0o Campylobacter jejuni Bact. Gram-neg inner 3 36 27.8 ± 0.6 0 ± 0 -183.8
1.1.14.01. Aquaporin-1 1j4n Bos taurus Eukaryo. plasma 4 32 31.8 ± 1.0 0 ± 0 -129.2
1.1.12.14. TRPV6 channel, structure 1, tetramer 5iwk Rattus norvegicus Eukaryo. plasma 4 24 30.4 ± 0.6 0 ± 0 -244.6
1.3.18.01. Maltoporin 1af6 Escherichia coli Bact. Gram-neg outer 3 54 25.1 ± 0.7 0 ± 0 -117.9
1.1.61.01. Leukotriene C4 synthase 2uuh Homo sapiens Endoplasm. reticulum 3 12 29.4 ± 1.1 0 ± 0 -55.2
1.1.12.20. KCNQ1 channel, with calmodulin 5vms Xenopus laevis Eukaryo. plasma 4 24 31.4 ± 0.4 0 ± 0 -259.2
1.2.23.01. M2 proton channel of Influenza A, S31N, crystal structure 5c02 Influenza virus Viral 4 4 28.6 ± 1.9 0 ± 0 -53.5
1.1.01.01. Deltarhodopsin 4fbz Haloterrigena thermotolerans Archaebac. 3 21 31.6 ± 0.8 0 ± 0 -110.6
1.1.28.02. Efflux transporter CusA, complex with CusB, pre-extrusion state 3t56 Escherichia coli Bact. Gram-neg inner 3 36 30.4 ± 0.6 0 ± 0 -153.7
1.1.06.01. Cytochrome bc1, mitochondrial 3h1j Gallus gallus Mitochon. inner 10 24 28.2 ± 0.6 0 ± 0 -184.8
1.2.23.01. M2 proton channel of Influenza A, inward-open state 5um1 Influenza virus Viral 4 4 28.6 ± 1.6 0 ± 0 -55.1
1.1.104.01. TRIC cation channel 5h35 Sulfolobus solfataricus Archaebac. 3 21 27.4 ± 0.8 0 ± 0 -112.8
1.1.16.01. Glutamate receptor 2, with antagonist, structure 1 3kg2 Rattus norvegicus Eukaryo. plasma 4 12 31.8 ± 2.0 0 ± 0 -93.0
1.1.34.01. Mitochondrial ADP-ATP carrier, dimer, conformation 1 4c9h Saccharomyces cerevisiae Mitochon. inner 2 12 30.4 ± 0.7 0 ± 0 -121.4
1.1.05.05. Succinate dehydrogenase 1nek Escherichia coli Bact. Gram-neg inner 6 18 32.0 ± 0.6 0 ± 0 -183.5
1.1.01.02. Beta-1 adrenergic receptor, inactive, dimer 4gpo Meleagris gallopavo Eukaryo. plasma 2 14 30.8 ± 1.2 0 ± 0 -144.8
1.1.02.02. Photosystem I of cyanobacteria, complete trimeric complex 3pcq Thermosynechococcus elongatus Thylakoid 27 96 29.8 ± 0.8 0 ± 0 -429.6
1.2.25.01. Phospholamban, pentamer 1zll Homo sapiens Endoplasm. reticulum 5 5 30.5 ± 1.4 0 ± 2 -76.0
1.1.28.01. Multidrug efflux transporter AcrB with YajC subunit , symmetric 2rdd Escherichia coli Bact. Gram-neg inner 6 39 28.4 ± 0.5 0 ± 0 -156.2
1.1.13.02. 5u1x » P2X purinoceptor, structure 2 5u2h Ailuropoda melanoleuca Eukaryo. plasma 3 6 25.8 ± 0.2 0 ± 1 -14.8
1.1.08.01. V-type proton ATPase, vacuolar, state 2 3j9u Saccharomyces cerevisiae Vacuole 10 40 40.4 ± 1.1 0 ± 0 -180.4
1.1.12.16. TRPML1 (Mucolipin-1) channel, open 5wj9 Homo sapiens Lysosome 4 24 29.4 ± 0.4 0 ± 0 -219.8
1.2.43.01. Envelope glycoprotein, Dengue virus type 2, structure 1 1ok8 Dengue virus Viral 3 0 5.2 ± 0.9 0 ± 6 -9.5
1.1.15.01. 5-hydroxytryptamine receptor 3A 4pir Mus musculus Eukaryo. plasma 5 20 30.8 ± 1.0 0 ± 0 -153.9
1.1.64.01. Ca2+/H+ antiporter YfkE 4kjr Bacillus subtilis Bact. Gram-pos plas. 3 33 29.8 ± 0.4 0 ± 0 -181.6
1.1.12.09. Voltage-gated sodium channel Nav1.7- NavAb, with antagonist 5ek0 Arcobacter butzleri Bact. Gram-neg inner 4 24 30.2 ± 0.6 0 ± 0 -236.2
1.2.43.01. Capsid envelop protein complex, Dengue 3j2p Dengue virus Viral 4 8 22.8 ± 0.4 0 ± 0 -62.7
1.3.24.01. Outer membrane protein TolC, mutant, open conformation 3 2vdd Escherichia coli Bact. Gram-neg outer 3 12 24.4 ± 1.2 0 ± 0 -57.7
1.1.32.01. Proton glutamate symport protein, outward-facing state 3 5cfy Pyrococcus horikoshii Archaebac. 3 33 29.8 ± 0.3 0 ± 0 -185.9
1.1.15.02. Proton-gated ion channel, inactive conformation 4 4a97 Erwinia chrysanthemi Bact. Gram-neg inner 5 40 31.8 ± 0.5 0 ± 0 -125.8
1.1.14.01. Aquaporin-4 3gd8 Homo sapiens Eukaryo. plasma 4 32 29.8 ± 1.1 0 ± 1 -122.9
1.1.15.01. Glycine receptor, alpha-1, strychnine-bound state 3jad Danio rerio Eukaryo. plasma 5 20 30.8 ± 1.0 0 ± 0 -92.4
1.1.115.01. MlaA protein, with OMPF 5nup Klebsiella pneumoniae Bact. Gram-neg outer 6 54 23.0 ± 0.6 0 ± 0 -190.1
3.1.02.07. Na(+)/H(+) antiporter, TMH IV, fusion construct 2m7w Saccharomyces cerevisiae Eukaryo. plasma 3 3 26.8 ± 0.1 0 ± 2 -5.7
1.1.06.01. Cytochrome b6f, structure 4 4pv1 Mastigocladus laminosus Thylakoid 16 26 31.8 ± 0.5 0 ± 0 -215.7
1.1.14.01. Aquaporin-4 2d57 Rattus norvegicus Eukaryo. plasma 4 32 29.8 ± 1.1 0 ± 0 -126.2
1.2.31.01. Cytochrome c nitrite reductase complex 2j7a Desulfovibrio vulgaris Bact. Gram-neg inner 2 2 31.8 ± 3.1 0 ± 2 -42.9
1.2.26.01. Outer membrane lipoprotein Wza 2j58 Escherichia coli Bact. Gram-neg outer 8 8 31.1 ± 0.8 0 ± 0 -123.8
1.1.13.01. Acid-sensitive ion channel 1, with snake phospholipase A2 4ntx Gallus gallus Eukaryo. plasma 3 6 29.8 ± 1.8 0 ± 1 -51.0
1.1.12.01. Potassium channel KcsA, 17A opening conformer 3f7y Streptomyces lividans Bact. Gram-pos plas. 4 8 31.3 ± 1.3 0 ± 0 -82.3
1.1.54.01. Diacylglycerol kinase (DAGK), NMR model 2kdc Escherichia coli Bact. Gram-neg inner 3 9 25.5 ± 1.8 0 ± 0 -39.9
1.1.15.01. Glycine receptor, alpha-3, structure 2 5tin Homo sapiens Eukaryo. plasma 5 20 31.0 ± 0.6 0 ± 0 -133.9
1.1.14.01. Aquaporin-2, conformation 1 4nef Homo sapiens Eukaryo. plasma 4 24 28.6 ± 1.3 0 ± 0 -117.8
1.1.12.13. G protein-activated inward rectifier potassium channel 2 (GIRK2, Kir3.2) 3sya Mus musculus Eukaryo. plasma 4 8 34.8 ± 0.7 0 ± 0 -145.5
1.1.12.09. Sodium channel BacNaV, channel neck mutants 5hj8 Alkalilimnicola ehrlichei Bact. Gram-neg inner 4 8 30.6 ± 1.1 0 ± 0 -96.1
1.1.06.01. Cytochrome bc1, bacterial 2yiu Paracoccus denitrificans Bact. Gram-neg inner 6 20 29.8 ± 0.5 0 ± 0 -188.8
1.1.24.01. Bestrophin ion channel 4wd8 Klebsiella pneumoniae Bact. Gram-neg inner 5 20 27.4 ± 0.6 0 ± 0 -119.7
1.1.01.01. Bacteriorhodopsin-I 4qi1 Haloquadratum walsbyi Archaebac. 3 21 31.8 ± 1.2 0 ± 0 -129.9
1.1.108.01. Nitrate/nitrite sensor histidine kinase NarQ, structure 1 5iji Escherichia coli Bact. Gram-neg inner 2 4 31.8 ± 2.0 0 ± 1 -57.1
1.1.12.15. Ryanodine receptor 1, various structures 5gl0 Oryctolagus cuniculus Endoplasm. reticulum 4 24 30.8 ± 0.0 0 ± 0 -202.9
1.1.08.01. F1F0 ATP synthase, F0F1 complex, more complete model 4b2q Saccharomyces cerevisiae Mitochon. inner 10 20 38.4 ± 0.9 0 ± 0 -115.7
1.1.02.05. Light-harvesting complex 1lgh Rhodospirillum molischianum Bact. Gram-neg inner 16 16 29.7 ± 0.5 0 ± 0 -163.4
1.1.14.01. Aquaporin-0 1ymg Bos taurus Eukaryo. plasma 4 32 31.3 ± 1.2 0 ± 0 -138.4
1.3.18.01. Maltoporin 2mpr Salmonella enterica Bact. Gram-neg outer 3 54 24.5 ± 1.0 0 ± 0 -109.7
1.1.18.01. Mechanosensitive channel MscL, closed state 2oar Mycobacterium tuberculosis Bact. Gram-pos plas. 5 10 36.1 ± 2.2 0 ± 0 -142.7
1.1.41.01. Magnesium ion transporter-E (MgtE), structure 2 4u9n Thermus thermophilus Bact. Gram-neg inner 2 10 31.8 ± 0.8 0 ± 0 -85.3
1.1.26.04. Glycine betaine transporter BetP, asymmetric trimer, conformation 1 4ain Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 29.8 ± 0.6 0 ± 0 -198.8
1.1.28.02. Efflux transporter CusA, complex with CusB 3ne5 Escherichia coli Bact. Gram-neg inner 3 36 29.0 ± 0.7 0 ± 0 -165.0
1.1.14.01. Aquaporin AqpM 3ne2 Archaeoglobus fulgidus Archaebac. 4 24 31.2 ± 1.3 0 ± 0 -143.5
1.1.29.01. YddG transporter 5i20 Starkeya novella Bact. Gram-neg inner 1 10 30.2 ± 1.3 0 ± 0 -78.1
3.1.07.02. Transmembrane domain of HIV-1 gp41 (677-716), trimer 5jyn Human immunodeficiency virus type 1 Viral 3 3 36.0 ± 1.6 0 ± 2 -22.0
1.1.01.01. Halorhodopsin, different conformation 3vvk Natronomonas pharaonis Archaebac. 3 21 33.6 ± 1.1 0 ± 0 -140.5
1.1.01.02. Beta-2 adrenergic receptor, inactive state, dimer 2rh1 Homo sapiens Eukaryo. plasma 2 14 31.8 ± 0.9 0 ± 1 -143.2
1.1.01.01. Sensory rhodopsin II, tetramer, structure 2 5jje Natronomonas pharaonis Archaebac. 4 18 30.2 ± 0.8 0 ± 0 -116.8
1.1.35.03. Citrate-sodium symporter CitS, structure 1 5xar Klebsiella pneumoniae Bact. Gram-neg inner 2 22 30.2 ± 0.6 0 ± 0 -138.2
1.1.13.02. ATP-gated P2X4 ion channel, open state 4dw1 Danio rerio Eukaryo. plasma 3 6 26.8 ± 0.6 0 ± 0 -56.0
1.1.28.01. Multidrug efflux transporter AcrB, symmetric 3d9b Escherichia coli Bact. Gram-neg inner 3 36 28.4 ± 0.6 0 ± 0 -189.9
1.1.14.01. Aquaporin-4, different conformation of loops with lipids 2zz9 Rattus norvegicus Eukaryo. plasma 4 28 29.5 ± 0.7 0 ± 0 -115.6
1.1.12.13. Potassium channel Kirbac1.1, closed state 1p7b Burkholderia pseudomallei Bact. Gram-neg inner 4 8 33.1 ± 1.3 0 ± 0 -111.9
1.2.11.01. Capsid protein G8P 1ifi Bacteriophage fd Secreted 15 15 36.8 ± 0.2 0 ± 0 -69.8
1.1.12.13. Potassium channel Kir 2.2, structure 2 5kuk Gallus gallus Eukaryo. plasma 4 8 30.8 ± 0.2 0 ± 0 -108.3
1.1.12.01. Potassium channel KcsA, full-length, closed 3eff Streptomyces lividans Bact. Gram-pos plas. 4 8 31.8 ± 1.3 0 ± 0 -107.3
1.1.08.01. V-type proton ATPase, vacuolar, state 3 3j9v Saccharomyces cerevisiae Vacuole 10 40 40.0 ± 1.2 0 ± 0 -178.0
1.1.25.05. Nitrate transporter NRT1/ PTR, dimer 4oh3 Arabidopsis thaliana Eukaryo. plasma 2 24 29.0 ± 0.9 0 ± 0 -106.0
1.1.12.16. TRPML1 (Mucolipin-1) channel, closed I 5wpq Mus musculus Lysosome 4 24 31.4 ± 0.8 0 ± 0 -194.7
1.1.01.01. Sodium pumping rhodopsin, NaR, pentamer 4xto Dokdonia eikasta Bact. Gram-neg inner 5 35 29.8 ± 0.5 0 ± 0 -170.3
1.1.98.01. Polyisoprenyl-phosphate glycosyltransferase GtrB 5eke Synechocystis sp. Bact. Gram-neg inner 4 8 31.4 ± 1.2 0 ± 0 -82.3
1.2.23.01. M2 proton channel of Influenza A, closed state, S31N, with drug 2ly0 Influenza virus Viral 4 4 34.0 ± 1.6 0 ± 0 -67.5
1.3.24.01. Outer membrane protein TolC, mutant, open conformation 4 2xmn Escherichia coli Bact. Gram-neg outer 3 12 23.6 ± 1.4 0 ± 0 -50.5
1.1.84.01. Bifunctional IPC transferase and DIPP synthase 4mnd Archaeoglobus fulgidus Archaebac. 2 12 30.2 ± 1.0 0 ± 0 -86.4
1.1.65.01. Concentrative nucleoside transporter, outward-facing state 5l2a Neisseria wadsworthii Bact. Gram-neg inner 3 24 27.8 ± 0.6 0 ± 0 -164.7
1.3.25.01. Aerolysin 5jzt Aeromonas hydrophila Secreted 7 14 22.8 ± 3.0 0 ± 0 -59.5
1.1.72.01. Dicarboxylate/sodium symporter NadC 5uld Vibrio cholerae Bact. Gram-neg inner 2 28 30.2 ± 0.6 0 ± 1 -106.9
1.1.20.01. Connexin 26 gap junction channel, structure 1 2zw3 Homo sapiens Eukaryo. plasma 6 24 32.2 ± 0.5 0 ± 0 -155.9
1.1.50.01. Particulate methane monooxygenase 1yew Methylococcus capsulatus Bact. Gram-neg inner 9 42 28.2 ± 0.7 0 ± 0 -188.5
1.1.15.01. Glycine receptor, alpha-1, glycine-bound state 3jae Danio rerio Eukaryo. plasma 5 20 31.8 ± 0.4 0 ± 0 -191.1
1.1.111.01. Prokaryotic otassium channel TMEM175 5vre Chamaesiphon minutus Bact. Gram-neg inner 4 24 30.2 ± 1.4 0 ± 0 -125.4
1.1.50.01. Particulate methane monooxygenase, different structure 3rgb Methylococcus capsulatus Bact. Gram-neg inner 9 39 28.2 ± 0.6 0 ± 0 -204.9
1.1.02.03. Photosystem II 3wu2 Thermosynechococcus vulcanus Thylakoid 32 70 32.4 ± 0.5 0 ± 0 -409.1
1.1.15.01. Nicotinic acetylcholine receptor, alpha-4/beta-2 5kxi Homo sapiens Eukaryo. plasma 5 20 33.2 ± 0.7 0 ± 0 -133.0
1.1.16.01. Glutamate receptor 2, with noncompetitive inhibitor 5l1h Rattus norvegicus Eukaryo. plasma 4 12 36.4 ± 0.7 0 ± 0 -100.1
1.3.16.03. Porin OprP 2o4v Pseudomonas aeruginosa Bact. Gram-neg outer 3 48 23.9 ± 1.1 0 ± 0 -129.6
1.1.12.01. Potassium channel KcsA, 23A opening conformer 3f7v Streptomyces lividans Bact. Gram-pos plas. 4 8 30.1 ± 1.1 0 ± 0 -95.2
1.1.041.01. Bacterial semiSWEET transporter 4qnd Vibrio sp. Bact. Gram-neg inner 2 6 33.0 ± 1.7 0 ± 0 -61.5
1.1.26.05. Arginine/agmatine antiporter (AdiC), outward-facing conformation 3hqk Salmonella enterica Bact. Gram-neg inner 2 26 29.8 ± 1.0 0 ± 0 -124.6
1.1.26.04. L-carnitine/gamma-butyrobetaine antiporter CaiT, open inward-facing conformation 2wsw Proteus mirabilis Bact. Gram-neg inner 3 42 29.8 ± 0.5 0 ± 0 -218.9
1.1.17.01. Ammonium transporter Amt-1 2b2f Archaeoglobus fulgidus Archaebac. 3 33 28.9 ± 0.7 0 ± 0 -152.5
1.1.16.01. Glutamate receptor 2, with conotoxin, structure 1 4u5b Rattus norvegicus Eukaryo. plasma 4 12 31.6 ± 1.1 0 ± 0 -91.5
1.1.15.02. Proton-gated ion channel, conformation 4 5heo Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.0 ± 0.8 0 ± 0 -121.8
1.1.15.02. Proton-gated ion channel, conformation 8 5l4h Gloeobacter violaceus Bact. Gram-neg inner 5 20 31.8 ± 1.4 0 ± 1 -175.1
1.1.61.01. Leukotriene C4 synthase 4ntf Mus musculus Endoplasm. reticulum 3 12 29.8 ± 1.8 0 ± 2 -72.6
1.1.08.01. F1F0 ATP synthase, F0F1 complex 2xok Saccharomyces cerevisiae Mitochon. inner 10 20 35.3 ± 1.3 0 ± 0 -58.9
1.3.25.01. Necrotic enteritis toxin B, NetB 4h56 Clostridium perfringens Secreted 7 17 25.2 ± 0.8 0 ± 0 -50.7
1.1.25.06. D-xylose-proton symporter xylE, conformation 3 4ja4 Escherichia coli Bact. Gram-neg inner 1 12 28.2 ± 1.3 0 ± 0 -82.8
1.3.18.01. Sucrose-specific porin 1a0s Salmonella enterica Bact. Gram-neg outer 3 54 23.8 ± 1.1 0 ± 0 -103.5
1.1.12.01. Potassium channel KcsA 1r3j Streptomyces lividans Bact. Gram-pos plas. 4 8 34.8 ± 1.2 0 ± 0 -111.0
1.1.12.04. Bacterial cyclic nucleotide regulated ion channel, full structure 4chw Rhizobium loti Bact. Gram-neg inner 4 24 29.8 ± 0.6 0 ± 0 -187.8
1.1.28.01. Multidrug efflux transporter AcrB-AcrZ complex, structure 1 4c48 Escherichia coli Bact. Gram-neg inner 6 39 29.2 ± 0.8 0 ± 0 -217.3
1.1.66.01. Proton-translocating pyrophosphatase, structure 1 4a01 Vigna radiata (Mung bean) Vacuole 2 32 32.0 ± 0.8 0 ± 0 -189.3
1.1.15.01. Gamma-aminobutyric acid receptor, GABA 4cof Homo sapiens Eukaryo. plasma 5 20 31.6 ± 0.6 0 ± 0 -158.5
1.1.12.01. Potassium channel KcsA, 16 A opening conformer 3fb6 Streptomyces lividans Bact. Gram-pos plas. 4 8 30.2 ± 1.0 0 ± 0 -86.1
1.1.15.02. Proton-gated ion channel, Glic/Elic chimera 4yeu Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.6 ± 1.1 0 ± 0 -162.5
1.1.09.01. Copper efflux ATPase, CopA 3j08 Archaeoglobus fulgidus Archaebac. 2 16 27.6 ± 0.8 0 ± 0 -72.3
1.1.12.19. ATP-sensitive K+ channel SUR1/Kir6.2, structure 1 6baa Rattus norvegicus Eukaryo. plasma 8 76 31.4 ± 0.4 0 ± 0 -443.7
1.2.43.07. Glycoprotein C, structure 1 5j81 Puumala virus Viral 3 0 6.0 ± 0.3 0 ± 1 -15.7
1.1.26.01. Leucine transporter LeuT, outward-facing conformation, from bicelles 4fxz Aquifex aeolicus Bact. Gram-neg inner 2 24 28.0 ± 0.6 0 ± 0 -144.3
1.1.12.02. Potassium channel Kv1.2 - Kv2.1. chimera, in membrane-like environment 2r9r Rattus norvegicus Eukaryo. plasma 4 28 30.8 ± 0.6 0 ± 0 -252.0
1.1.104.01. TRIC cation channel, structure 1 5wud Sulfolobus acidocaldarius Archaebac. 3 21 28.2 ± 1.0 0 ± 0 -141.2
1.3.20.01. Bacterial Zn-transporter ZnuD, structure 2 4rdt Neisseria meningitidis Bact. Gram-neg outer 1 22 23.4 ± 0.8 0 ± 0 -72.6
1.1.12.13. Potassium channel Kir 2.2, structure 1 3jyc Gallus gallus Eukaryo. plasma 4 8 30.5 ± 1.4 0 ± 1 -119.9
1.2.11.01. Capsid protein G8P 1ifk Bacteriophage If1 Secreted 15 15 31.8 ± 0.7 0 ± 0 -83.5
1.1.12.16. Polycystin-2 channel, structure 1 5k47 Homo sapiens Eukaryo. plasma 4 24 30.8 ± 0.0 0 ± 0 -231.6
1.1.12.11. NaK potassium channel, open state, mutant with DMA 4r7c Bacillus cereus Bact. Gram-pos plas. 4 8 27.8 ± 0.9 0 ± 0 -41.0
1.1.01.01. Sensory rhodopsin, dimer 4tl3 Nostoc sp. Bact. Gram-neg inner 2 17 30.6 ± 1.1 0 ± 0 -116.0
1.1.12.07. Two pore calcium channel TPC1 5dqq Arabidopsis thaliana Vacuole 2 24 29.8 ± 0.5 0 ± 0 -188.0
1.1.12.16. TRPML1 (Mucolipin-1) channel, closed II 5wpt Mus musculus Lysosome 4 24 31.0 ± 0.4 0 ± 0 -226.1
1.1.72.02. Antibiotic resistance efflux pump MtrF 4r1i Neisseria gonorrhoeae Bact. Gram-neg inner 2 22 28.9 ± 1.4 0 ± 0 -118.2
1.1.26.04. L-carnitine/gamma-butyrobetaine antiporter CaiT, substrate-bound 3hfx Escherichia coli Bact. Gram-neg inner 3 42 29.8 ± 0.8 0 ± 0 -203.5
1.1.15.01. Glutamate-gated chloride channel GluCl, POPC-bound conformation 4tnw Caenorhabditis elegans Eukaryo. plasma 5 20 30.6 ± 0.9 0 ± 0 -125.0
1.1.10.02. ABC-type polar amino acid transporter 4ymu Caldanaerobacter subterraneus Bact. Gram-pos plas. 2 10 29.8 ± 0.8 0 ± 0 -71.5
1.1.28.01. AcrAB-TolC efflux pump, structure 1 5v78 Escherichia coli Bact. Gram-neg inner 3 39 27.0 ± 1.0 0 ± 0 -156.1
1.1.10.09. MacAB-TolC efflux pump 5nik Escherichia coli Bact. Gram-neg inner 2 8 34.6 ± 2.0 0 ± 0 -96.2
1.1.15.01. Glycine receptor, alpha-1, glycine/ivermectin-bound state 3jaf Danio rerio Eukaryo. plasma 5 20 33.4 ± 1.4 0 ± 0 -180.2
1.1.02.06. Light-Harvesting Complex II 1rwt Spinacia oleracea Thylakoid 3 9 30.0 ± 0.7 0 ± 0 -154.0
1.1.01.02. C-X-C chemokine receptor type 4, inactive, dimer, complex with antagonist 3odu Homo sapiens Eukaryo. plasma 2 14 31.2 ± 1.1 0 ± 0 -129.5
1.1.07.01. Mitochondrial cytochrome c oxidase, with cytochrome c 5iy5 Bos taurus Mitochon. inner 20 56 25.8 ± 1.2 0 ± 0 -204.7
1.3.12.01. Outer membrane phospholipase A, dimer 1qd6 Escherichia coli Bact. Gram-neg outer 2 24 23.9 ± 1.0 0 ± 0 -77.2
1.1.12.02. Potassium channel Kv1.2. - Kv2.1. chimera, complex with Charybdotoxin 4jtc Rattus norvegicus Eukaryo. plasma 4 24 30.2 ± 0.4 0 ± 0 -247.3
1.1.02.03. Photosystem II 4pj0 Thermosynechococcus elongatus Thylakoid 34 72 30.8 ± 0.6 0 ± 0 -471.8
1.1.13.02. P2X purinoceptor 3, closed, apo state 5svj Homo sapiens Eukaryo. plasma 3 6 34.2 ± 0.8 0 ± 0 -58.1
1.1.41.01. Magnesium ion transporter-E (MgtE), structure 1 2yvx Thermus thermophilus Bact. Gram-neg inner 2 10 31.1 ± 0.9 0 ± 0 -69.2
1.1.01.02. Rhodopsin, constitutively active mutant (metarhodopsin II), dimer 2x72 Bos taurus Eukaryo. plasma 2 14 30.0 ± 0.6 0 ± 0 -132.0
1.1.12.01. Potassium channel KcsA, 14.5 A opening conformer 3fb5 Streptomyces lividans Bact. Gram-pos plas. 4 8 33.7 ± 0.9 0 ± 0 -115.9
1.1.12.16. Polycystin-2 channel, structure 3 5mkf Homo sapiens Eukaryo. plasma 4 24 29.0 ± 1.2 0 ± 1 -164.0
1.1.14.01. Aquaporin-2, conformation 2 4oj2 Homo sapiens Eukaryo. plasma 4 24 29.0 ± 0.7 0 ± 0 -125.9
1.1.15.02. Proton-gated ion channel, conformation 5 5heh Gloeobacter violaceus Bact. Gram-neg inner 5 20 33.4 ± 1.0 0 ± 0 -183.3
1.1.21.01. Magnesium transport protein CorA 4ev6 Methanococcus jannaschii Archaebac. 5 10 28.4 ± 1.5 0 ± 1 -92.4
1.3.25.01. Gamma-hemolysin, complete channel, hetero-octamer (A+B) 3b07 Staphylococcus aureus Secreted 8 16 21.4 ± 1.0 0 ± 0 -32.8
1.1.18.01. Mechanosensitive channel MscL, closed state 4y7k Methanosarcina acetivorans Archaebac. 5 10 31.8 ± 0.1 0 ± 0 -121.6
1.1.104.01. Trimeric intracellular cation channel, structure 1 5eik Caenorhabditis elegans Endoplasm. reticulum 3 21 26.8 ± 0.3 0 ± 0 -45.3
1.1.19.01. Mechanosensitive channel protein MscS, closed state 4hw9 Helicobacter pylori Bact. Gram-neg inner 7 14 31.6 ± 1.8 0 ± 0 -140.9
1.1.06.01. Cytochrome bc1, mitochondrial, structure 2 2fyu Bos taurus Mitochon. inner 12 26 29.8 ± 0.5 0 ± 0 -182.9
1.1.17.01. Ammonium transporter MEP2 5aex Saccharomyces cerevisiae Eukaryo. plasma 3 33 29.4 ± 1.4 0 ± 0 -121.0
1.1.02.06. Light-Harvesting Complex II 2bhw Pisum sativum Thylakoid 3 9 29.4 ± 1.0 0 ± 0 -123.2
1.1.15.01. Glycine receptor, alpha-1 2m6i Homo sapiens Eukaryo. plasma 5 20 26.8 ± 0.3 0 ± 0 -92.1
1.1.12.01. Potassium channel KcsA 1s5h Streptomyces coelicolor Bact. Gram-pos plas. 4 8 33.7 ± 1.3 0 ± 1 -111.9
1.1.12.04. Bacterial cyclic nucleotide regulated ion channel, full structure, with cAMP 4chv Rhizobium loti Bact. Gram-neg inner 4 24 28.4 ± 0.5 0 ± 0 -138.2
1.1.20.02. Innexin-6 gap junction channel 5h1r Caenorhabditis elegans Eukaryo. plasma 8 40 30.6 ± 0.4 0 ± 0 -233.4
1.1.14.02. Formate transporter 1, FocA 3kcu Escherichia coli Bact. Gram-neg inner 5 35 29.9 ± 0.7 0 ± 0 -160.9
1.1.16.01. Glutamate receptor ionotropic, NMDA 1 4pe5 Rattus norvegicus Eukaryo. plasma 4 12 28.6 ± 0.8 0 ± 0 -25.4
1.1.12.01. Potassium channel KcsA, 20 A opening conformer 3fb8 Streptomyces lividans Bact. Gram-pos plas. 4 8 29.8 ± 0.4 0 ± 0 -68.2
1.1.10.02. Molybdate transporter ModBC, open state 2onk Archaeoglobus fulgidus Archaebac. 2 12 32.0 ± 1.7 0 ± 1 -100.7
1.1.12.01. Potassium channel KcsA, structure 2 4uuj Streptomyces lividans Bact. Gram-pos plas. 4 8 29.8 ± 0.5 0 ± 0 -90.2
1.1.40.01. Glutamate-dependent intramembrane protease Rce1 4cad Saccharomyces cerevisiae Endoplasm. reticulum 1 8 30.8 ± 1.3 0 ± 1 -86.1
1.1.32.01. Proton/glutamate symporter, apo 5dwy Pyrococcus kodakaraensis Archaebac. 3 24 30.8 ± 0.6 0 ± 0 -184.1
1.1.12.09. Voltage-gated sodium channel NavAb, structure 4 (closed) 5vb2 Arcobacter butzleri Bact. Gram-neg inner 4 24 31.0 ± 0.8 0 ± 0 -228.1
1.1.66.01. K(+)-pumping pyrophosphatase, structure 1 4av3 Thermotoga maritima Bact. Gram-neg inner 2 32 29.8 ± 0.7 0 ± 0 -182.5
1.1.104.01. TRIC cation channel, structure 2 5wue Sulfolobus acidocaldarius Archaebac. 3 21 28.2 ± 0.4 0 ± 0 -121.8
1.1.102.01. STRA6 receptor, with calmodulin 5sy1 Danio rerio Eukaryo. plasma 2 18 30.8 ± 0.0 0 ± 0 -141.2
1.1.14.01. Aquaporin TIP2-1 5i32 Arabidopsis thaliana Vacuole 4 24 30.0 ± 0.8 0 ± 0 -154.0
1.1.12.10. Voltage-gated K+ channel 4h33 Listeria monocytogenes Bact. Gram-pos plas. 4 8 33.2 ± 1.9 0 ± 0 -115.9
1.1.12.16. TRPML1 (Mucolipin-1) channel, closed III 5wpv Mus musculus Lysosome 4 24 31.0 ± 0.4 0 ± 0 -214.3
1.1.01.01. Sodium pumping rhodopsin, NaR, dimer 3x3b Dokdonia eikasta Bact. Gram-neg inner 2 14 29.8 ± 0.9 0 ± 0 -87.5
1.1.16.01. Glutamate receptor 2, with auxiliary subunit GSG1L, structure 1 5vhy Rattus norvegicus Eukaryo. plasma 4 20 33.0 ± 0.8 0 ± 0 -176.6
1.2.23.01. M2 proton channel of Influenza A, open state, ligand-free 4qkm Influenza virus Viral 4 4 28.4 ± 1.7 0 ± 0 -55.4
1.1.12.10. Potassium channel KvAP, complex with Fab 1orq Aeropyrum pernix Archaebac. 4 12 29.3 ± 1.6 0 ± 0 -78.6
1.1.15.01. Glutamate-gated chloride channel GluCl, apo (non-conducting state) 4tnv Caenorhabditis elegans Eukaryo. plasma 5 20 30.8 ± 1.5 0 ± 0 -106.1
1.1.06.01. Cytochrome bc1, bacterial, structure 1 2qjy Rhodobacter sphaeroides Bact. Gram-neg inner 6 20 30.2 ± 0.6 0 ± 0 -188.6
1.1.16.01. Glutamate receptor 2, with auxiliary subunit GSG1L, structure 4 5wel Rattus norvegicus Eukaryo. plasma 4 20 33.0 ± 1.0 0 ± 0 -157.2
1.1.12.05. Calcium-gated potassium channel MthK 3ldc Methanobacterium thermoautotrophicum Archaebac. 4 8 29.8 ± 0.8 0 ± 0 -72.4
1.1.08.01. ATP synthase F0 rotor ring 4v1f Mycobacterium phlei Bact. Gram-pos plas. 9 18 33.4 ± 1.4 0 ± 0 -58.6
1.1.32.01. Proton glutamate symport protein, outward-facing state 4 4oye Pyrococcus horikoshii Archaebac. 3 30 28.2 ± 0.6 0 ± 0 -168.8
1.3.24.01. MtrE protein 4mt0 Neisseria gonorrhoeae Bact. Gram-neg outer 3 12 25.0 ± 0.7 0 ± 0 -57.4
1.1.28.01. AcrAB-TolC efflux pump, structure 2 5v5s Escherichia coli Bact. Gram-neg inner 3 36 28.6 ± 1.0 0 ± 0 -180.0
1.1.14.01. Aquaporin Z 1rc2 Escherichia coli Bact. Gram-neg inner 4 32 29.7 ± 1.3 0 ± 0 -118.7
1.1.06.01. Cytochrome b6f 1q90 Chlamydomonas reinhardtii Thylakoid 16 26 31.8 ± 1.0 0 ± 1 -226.4
1.3.32.01. Type II secretion system protein GspD, pathogenic E. coli 5w68 Escherichia coli Bact. Gram-neg outer 15 60 19.4 ± 0.2 0 ± 0 -147.2
1.1.26.06. Uric acid-xanthine permease 5i6c Emericella nidulans Eukaryo. plasma 2 28 29.2 ± 1.0 0 ± 0 -119.2
1.1.12.13. G protein-activated inward rectifier potassium channel 2 4kfm Mus musculus Eukaryo. plasma 4 8 33.6 ± 1.2 0 ± 0 -120.7
1.1.15.02. Proton-gated ion channel, conformation 2 4lmj Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.4 ± 0.7 0 ± 0 -177.4
1.1.13.02. P2X purinoceptor 3, open state 5svk Homo sapiens Eukaryo. plasma 3 6 31.6 ± 0.8 0 ± 0 -81.4
1.1.15.02. Proton-gated ion channel, pore blocker-bound conformation 4twd Erwinia chrysanthemi Bact. Gram-neg inner 5 20 32.0 ± 0.6 0 ± 0 -127.8
1.1.14.02. Formate/nitrite transporter 3tdp Clostridium difficile Bact. Gram-pos plas. 5 30 28.4 ± 1.9 0 ± 0 -161.3
1.1.12.10. Potassium channel KvAP 2a0l Aeropyrum pernix Archaebac. 4 12 29.5 ± 1.1 0 ± 0 -100.0
1.3.16.01. Porin B (PorB) 4aui Neisseria gonorrhoeae Bact. Gram-neg outer 3 48 24.2 ± 0.8 0 ± 0 -89.7
1.1.08.01. F1F0 ATP synthase, F0 complex 4bem Acetobacterium woodii Bact. Gram-pos plas. 10 22 34.8 ± 1.1 0 ± 0 -102.9
1.1.15.02. Proton-gated ion channel, conformation 6 5heg Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.0 ± 0.8 0 ± 0 -186.8
1.1.01.01. Chimaera of channelrhodopsins 1 and 2 3ug9 Chlamydomonas reinhardtii Eukaryo. plasma 2 14 31.0 ± 1.2 0 ± 0 -100.3
1.1.57.02. Intramembrane aspartate protease 4hyg Methanoculleus marisnigri Archaebac. 3 27 31.8 ± 0.3 0 ± 0 -172.7
1.1.108.01. Nitrate/nitrite sensor histidine kinase NarQ, structure 4 5jgp Escherichia coli Bact. Gram-neg inner 2 4 31.4 ± 1.2 0 ± 0 -56.7
1.1.17.01. Rhesus Glycoprotein RhCG 3hd6 Homo sapiens Eukaryo. plasma 3 36 31.8 ± 0.7 0 ± 0 -174.1
1.1.06.01. Cytochrome bc1, mitochondrial, bovine/chicken, structure 1 1bcc Bos taurus Mitochon. inner 24 10 29.8 ± 0.6 0 ± 0 -197.0
1.1.17.01. Ammonium transporter MEP2, structure 1 5aez Candida albicans Eukaryo. plasma 3 33 32.4 ± 0.8 0 ± 0 -154.4
1.3.32.01. Type II secretion system protein XcpQ 5wln Pseudomonas aeruginosa Bact. Gram-neg inner 15 60 21.0 ± 1.2 0 ± 0 -254.1
1.1.06.01. Cytochrome b6f, structure 1 2e74 Mastigocladus laminosus Thylakoid 16 26 31.2 ± 0.8 0 ± 0 -222.1
1.1.01.02. C-C chemokine receptor type 5 4mbs Homo sapiens Eukaryo. plasma 1 7 34.4 ± 1.5 0 ± 0 -88.8
1.1.08.01. V-type Sodium ATPase 2bl2 Enterococcus hirae Bact. Gram-pos plas. 10 40 35.6 ± 0.7 0 ± 0 -189.6
1.1.12.11. NaK potassium channel, different strain of Bacillus cereus 3ouf Bacillus cereus Bact. Gram-pos plas. 4 8 27.9 ± 1.3 0 ± 0 -91.0
1.1.041.01. Bacterial semiSWEET transporter, inward-open conformation 4x5m Escherichia coli Bact. Gram-neg inner 2 6 31.6 ± 1.9 0 ± 3 -66.6
1.1.17.02. Urea transporter 3k3f Desulfovibrio vulgaris Bact. Gram-neg inner 3 30 29.4 ± 0.8 0 ± 0 -124.4
1.1.12.01. Potassium channel KcsA, complex with Rb+ 3fb7 Streptomyces lividans Bact. Gram-pos plas. 4 8 28.6 ± 1.2 0 ± 0 -79.0
1.3.25.04. Protective antigen 3j9c Bacillus anthracis Secreted 7 14 34.6 ± 1.2 0 ± 0 -76.8
1.1.12.09. Voltage-gated sodium channel NavAb, structure 5 (open) 5vb8 Arcobacter butzleri Bact. Gram-neg inner 4 24 31.4 ± 0.8 0 ± 0 -229.5
1.3.16.03. Porin OprO 4rjw Pseudomonas aeruginosa Bact. Gram-neg outer 3 48 25.4 ± 0.7 0 ± 0 -129.0
1.1.12.02. Potassium channel Kv1.2. - Kv2.1. chimera 3lnm Rattus norvegicus Eukaryo. plasma 4 28 31.1 ± 0.9 0 ± 0 -260.7
1.1.06.01. Cytochrome bc1, mitochondrial, with cytochrome c iso-2 3cxh Saccharomyces cerevisiae Mitochon. inner 24 10 27.6 ± 1.1 0 ± 0 -167.0
1.3.20.01. SusD-SusC complex, BT_2263, a dimer 5fq6 Bacteroides thetaiotaomicron Bact. Gram-neg outer 2 44 26.6 ± 2.2 0 ± 0 -142.4
1.1.80.01. Phospho-N-acetylmuramoyl-pentapeptide-transferase, structure 1 4j72 Aquifex aeolicus Bact. Gram-neg inner 2 20 31.4 ± 1.2 0 ± 0 -141.4
1.3.16.01. Phosphoporin (PhoE) 1pho Escherichia coli Bact. Gram-neg outer 3 48 24.1 ± 1.2 0 ± 0 -134.1
1.1.10.08. Cystic fibrosis transmembrane conductance regulator, dephosphorylated 5uar Danio rerio Endosome 1 12 30.6 ± 0.8 0 ± 0 -81.7
1.1.66.01. Proton-translocating pyrophosphatase, structure 2 5gpj Vigna radiata (Mung bean) Vacuole 2 32 31.0 ± 0.4 0 ± 0 -176.0
1.1.12.16. TRPML3 (mucolipin 3) channel, closed 5w3s Callithrix jacchus Lysosome 4 24 31.0 ± 0.8 0 ± 0 -213.0
1.1.12.13. Potassium channel Kirbac1.1, closed state, refined 2wll Burkholderia pseudomallei Bact. Gram-neg inner 4 8 33.4 ± 2.4 0 ± 0 -109.1
1.1.16.01. Glutamate receptor 2, with auxiliary subunit GSG1L, structure 2 5vhz Rattus norvegicus Eukaryo. plasma 6 20 33.0 ± 0.8 0 ± 0 -171.5
1.1.01.01. Bacteriorhodopsin 1m0l Halobacterium salinarum Archaebac. 3 21 31.8 ± 1.1 0 ± 1 -121.1
1.3.19.03. MOMP porin 5ldv Campylobacter jejuni Bact. Gram-neg outer 3 54 25.4 ± 0.6 0 ± 0 -125.2
1.1.35.02. Na+/H+ antiporter, outward-open conformation 5bz3 Thermus thermophilus Bact. Gram-neg inner 2 26 29.2 ± 0.8 0 ± 0 -108.2
1.1.16.01. Glutamate receptor 2-Cacng-2 subunit chimera, structure 3 5weo Rattus norvegicus Eukaryo. plasma 27 4 32.2 ± 1.2 0 ± 0 -236.7
1.1.14.02. Nitrite transporter NirC 4fc4 Salmonella typhimurium Bact. Gram-neg inner 5 35 33.8 ± 0.0 0 ± 0 -112.5
1.1.14.01. Glycerol uptake facilitator 1ldf Escherichia coli Bact. Gram-neg inner 4 32 30.1 ± 0.9 0 ± 0 -147.9
1.1.041.01. Bacterial semiSWEET transporter, structure 3 5uhs Leptospira biflexa Bact. Gram-neg inner 2 6 31.4 ± 1.4 0 ± 1 -68.5
1.1.14.01. Aquaporin-0, open state 2b6p Bos taurus Eukaryo. plasma 4 32 31.1 ± 1.5 0 ± 1 -130.0
1.1.02.02. Photosystem I of plants 4xk8 Arabidopsis thaliana Thylakoid 13 45 29.8 ± 0.5 0 ± 0 -319.6
1.1.15.02. Proton-gated ion channel, conformation 3 4lml Gloeobacter violaceus Bact. Gram-neg inner 5 20 31.8 ± 0.7 0 ± 0 -178.8
1.1.13.02. P2X purinoceptor 3, closed, agonist-bound 5svm Homo sapiens Eukaryo. plasma 3 6 30.8 ± 0.2 0 ± 0 -54.2
1.1.10.03. Lipid flippase MsbA, open state 3b60 Salmonella enterica Bact. Gram-neg inner 2 12 31.8 ± 0.9 0 ± 0 -98.5
1.3.16.01. Osmoporin OMPC, isoform 1 2ixx Escherichia coli Bact. Gram-neg outer 3 48 26.2 ± 1.3 0 ± 1 -142.5
1.1.36.01. ClC chloride transporter 3nd0 Synechocystis sp. Bact. Gram-neg inner 2 28 29.8 ± 0.7 0 ± 1 -120.9
1.1.14.01. Aquaporin AqpM 2f2b Methanobacterium thermoautotrophicum Archaebac. 4 32 29.0 ± 0.8 0 ± 0 -129.9
1.1.16.01. Glutamate receptor 2, with partial agonist, structure 5 4u4f Rattus norvegicus Eukaryo. plasma 4 12 30.2 ± 1.2 0 ± 0 -54.0
1.1.80.01. Phospho-N-acetylmuramoyl-pentapeptide-transferase, structure 2 5ckr Aquifex aeolicus Bact. Gram-neg inner 2 20 30.4 ± 1.1 0 ± 0 -149.3
1.2.23.01. M2 proton channel of Influenza A, drug-bound 2muv Influenza virus Viral 4 4 32.4 ± 1.1 0 ± 0 -59.2
1.1.01.01. Bacteriorhodopsin, different loop conformaton 1fbk Halobacterium salinarum Archaebac. 3 21 30.0 ± 1.2 0 ± 0 -127.8
1.1.104.01. TRIC cation channel 5h36 Rhodobacter sphaeroides Bact. Gram-neg inner 3 21 31.0 ± 1.0 0 ± 0 -124.3
1.1.65.01. Concentrative nucleoside transporter 3tij Vibrio cholerae Bact. Gram-neg inner 3 27 27.0 ± 0.5 0 ± 0 -155.2
1.1.17.02. Urea transporter 1 4ezc Bos taurus Eukaryo. plasma 3 30 31.2 ± 0.6 0 ± 0 -138.8
1.1.12.07. Potassium channel subfamily K member 1 3ukm Homo sapiens Eukaryo. plasma 2 8 31.8 ± 1.0 0 ± 0 -108.7
1.1.06.01. Cytochrome bc1, mitochondrial, bovine/chicken, structure 2 3bcc Bos taurus Mitochon. inner 24 10 28.6 ± 1.0 0 ± 0 -190.1
1.3.24.01. Multidrug efflux protein OprN 5azp Pseudomonas aeruginosa Bact. Gram-neg outer 3 12 24.2 ± 0.9 0 ± 0 -59.5
1.1.06.01. Cytochrome b6f 2zt9 Nostoc sp. Thylakoid 16 26 31.2 ± 1.0 0 ± 1 -214.2
1.1.01.01. Proteorhodopsin 4jq6 Gamma-proteobacterium Bact. Gram-neg inner 6 42 28.4 ± 1.3 0 ± 0 -188.5
1.1.61.01. Microsomal glutathione S-transferase 1, structure 1 2h8a Rattus norvegicus Endoplasm. reticulum 3 12 29.7 ± 0.7 0 ± 1 -47.7
1.1.15.02. Proton-gated ion channel, open state 3eam Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.7 ± 0.9 0 ± 1 -183.4
1.1.12.03. High conductance calcium-activated potassium channel, structure 1 5tj6 Aplysia californica Eukaryo. plasma 4 28 31.8 ± 0.6 0 ± 0 -273.6
1.1.32.01. Proton glutamate symport protein, outward-facing state 1 2nwl Pyrococcus horikoshii Archaebac. 3 39 29.8 ± 1.3 0 ± 0 -202.1
1.3.25.02. Cytolysin and hemolysin HlyA Pore-forming toxin 3o44 Vibrio cholerae Secreted 7 14 24.6 ± 0.0 0 ± 0 -33.1
1.1.01.01. Channelrhodopsin 2, structure 1 6eid Chlamydomonas reinhardtii Eukaryo. plasma 2 14 31.4 ± 0.8 0 ± 0 -106.6
1.1.29.02. Triose phosphate translocator 5y79 Galdieria sulphuraria Chloroplast inner 2 20 30.2 ± 1.4 0 ± 1 -132.8
1.1.26.06. Uracil permease, occluded state 5xls Escherichia coli Bact. Gram-neg inner 2 28 30.2 ± 0.8 0 ± 0 -143.6
1.1.61.01. Microsomal glutathione S-transferase 1, structure 2 5i9k Rattus norvegicus Endoplasm. reticulum 3 12 25.8 ± 0.2 0 ± 0 -26.4
1.1.26.01. Leucine transporter LeuT, outward-facing substrate-free conformation 3tt1 Aquifex aeolicus Bact. Gram-neg inner 2 24 28.2 ± 1.2 0 ± 0 -160.8
1.1.116.01. Glycerol-3-phosphate acyltransferase, structure 5 5xj9 Aquifex aeolicus Bact. Gram-neg inner 1 7 0.0 ± 0.0 0 ± 0 0.0
1.1.12.13. G protein-activated inward rectifier potassium channel 2, diff. conf. 3syq Mus musculus Eukaryo. plasma 4 8 31.6 ± 0.6 0 ± 0 -107.9
1.1.08.01. ATP synthase of chloroplast 3v3c Pisum sativum Thylakoid 14 28 32.0 ± 1.0 0 ± 0 -111.5
1.1.35.02. Na+/H+ antiporter 4bwz Thermus thermophilus Bact. Gram-neg inner 2 26 29.6 ± 0.6 0 ± 0 -120.8
1.1.12.02. Potassium channel Kv1.2. 2a79 Rattus norvegicus Eukaryo. plasma 4 28 29.8 ± 1.5 0 ± 0 -147.0
1.1.13.02. P2X purinoceptor 3, closed, ATP-bound 5svl Homo sapiens Eukaryo. plasma 3 6 30.8 ± 0.2 0 ± 1 -61.9
1.3.23.01. Autotransporter Hia, 992-1098 2gr7 Haemophilus influenzae Bact. Gram-neg outer 3 12 22.7 ± 2.0 0 ± 1 -43.5
1.1.12.11. NaK potassium channel, open state 3e86 Bacillus cereus Bact. Gram-pos plas. 4 8 27.6 ± 0.9 0 ± 0 -90.0
1.1.28.01. Drug efflux protein MtrD 4mt1 Neisseria gonorrhoeae Bact. Gram-neg inner 3 36 29.0 ± 0.3 0 ± 0 -214.1
1.1.28.01. Multidrug exporter MexB 2v50 Pseudomonas aeruginosa Bact. Gram-neg inner 3 36 28.6 ± 1.0 0 ± 1 -167.3
1.1.12.03. Na-activated potassium channel Slo2.2, open 5u70 Gallus gallus Eukaryo. plasma 4 24 31.4 ± 0.2 0 ± 0 -248.5
1.3.16.01. Porin B (PorB) 3a2s Neisseria meningitidis Bact. Gram-neg outer 3 48 24.4 ± 1.0 0 ± 0 -102.1
1.1.72.02. YdaH transporter 4r0c Alcanivorax borkumensis Bact. Gram-neg inner 2 22 29.8 ± 0.5 0 ± 0 -155.5
1.1.12.13. Potassium channel Kirbac3.1, closed conformation 2wlk Magnetospirillum magnetotacticum Bact. Gram-neg inner 4 8 29.8 ± 2.4 0 ± 0 -78.7
1.1.32.01. Excitatory amino acid transporter 1, structure 1 5llu Homo sapiens Eukaryo. plasma 3 36 31.4 ± 0.6 0 ± 0 -228.3
1.1.01.01. Sensory rhodopsin II, tetramer, structure 1 1h2s Natronomonas pharaonis Archaebac. 4 18 30.5 ± 1.1 0 ± 0 -123.4
1.1.39.03. Folate ECF transporter 4z7f Enterococcus faecalis Bact. Gram-pos plas. 1 6 30.6 ± 1.6 0 ± 1 -53.1
1.1.06.01. Cytochrome bc1, bacterial, structure 3 5kli Rhodobacter sphaeroides Bact. Gram-neg inner 6 20 29.8 ± 1.6 0 ± 0 -180.0
1.3.24.01. Outer membrane channel CmeC 4mt4 Campylobacter jejuni Bact. Gram-neg outer 3 12 26.8 ± 0.4 0 ± 0 -67.1
1.1.17.01. Ammonia Channel 1u7g Escherichia coli Bact. Gram-neg inner 3 33 29.8 ± 1.3 0 ± 0 -148.7
1.3.16.01. Porin 1 4d64 Providencia stuartii Bact. Gram-neg outer 3 48 26.0 ± 0.7 0 ± 0 -133.5
1.1.12.13. Potassium channel Kir 2.2, complex with inositol lipid 3spg Gallus gallus Eukaryo. plasma 4 8 30.8 ± 1.2 0 ± 0 -109.1
1.1.66.01. K(+)-pumping pyrophosphatase, structure 2 4av6 Thermotoga maritima Bact. Gram-neg inner 2 32 29.8 ± 0.8 0 ± 0 -173.1
1.1.06.01. Cytochrome bc1, mitochondrial, structure 4 5nmi Bos taurus Mitochon. inner 12 26 29.4 ± 1.0 0 ± 0 -161.4
1.1.12.13. Potassium channel Kir 2.2, complex with pyrophosphate lipid 3spc Gallus gallus Eukaryo. plasma 4 8 30.6 ± 1.2 0 ± 0 -120.3
1.3.16.01. Porin OmpF 3pox Escherichia coli Bact. Gram-neg outer 3 48 24.0 ± 0.8 0 ± 0 -136.2
1.1.02.06. Photoprotective protein PsbS 4ri2 Spinacia oleracea Thylakoid 2 8 29.8 ± 0.9 0 ± 0 -82.2
1.3.16.01. Osmoporin OMPC, isoform 2 2ixw Escherichia coli Bact. Gram-neg outer 3 48 24.5 ± 1.0 0 ± 0 -121.0
1.1.26.04. Glycine betaine transporter BetP, substrate-bound 2wit Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 30.4 ± 1.2 0 ± 0 -198.6
1.1.42.01. Nicotinamide riboside transporter PnuC 4qtn Neisseria mucosa Bact. Gram-neg inner 3 24 26.8 ± 0.7 0 ± 0 -112.0
1.1.26.03. Sodium/sugar symporter vSGLT, substrate-free 2xq2 Vibrio parahaemolyticus Bact. Gram-neg inner 2 30 30.4 ± 0.6 0 ± 0 -162.7
1.2.11.02. Capsid protein G8P 2mjz Bacteriophage M13 Viral 10 10 30.8 ± 0.3 0 ± 0 -20.4
1.1.43.01. Saccharide transporter, EIIC (ChbC), outward-facing 5iws Bacillus cereus Bact. Gram-pos plas. 2 20 31.2 ± 1.0 0 ± 0 -161.7
1.1.74.01. Calcium release-activated calcium channel protein 1 4hkr Drosophila melanogaster Eukaryo. plasma 6 24 30.0 ± 1.6 0 ± 0 -105.2
1.1.08.01. ATP synthase of chloroplast 2w5j Spinacia oleracea Thylakoid 14 28 32.8 ± 0.7 0 ± 0 -116.3
1.1.16.01. Glutamate receptor 2-Cacng-2 subunit chimera, structure 2 5kbu Rattus norvegicus Eukaryo. plasma 4 20 33.6 ± 1.4 0 ± 0 -109.5
1.1.08.01. F1F0 ATP synthase, F0 complex, conformation 1 2x2v Bacillus pseudofirmus Bact. Gram-pos plas. 13 26 35.3 ± 1.2 0 ± 0 -137.7
1.1.22.01. Pore-forming haemolysin E (ClyA) 2wcd Escherichia coli Secreted 12 36 30.8 ± 0.7 0 ± 0 -148.3
1.1.88.01. NAD(P) transhydrogenase, structure 1 4o9p Thermus thermophilus Bact. Gram-neg inner 4 24 29.8 ± 0.9 0 ± 0 -162.0
1.1.61.01. FLAP protein (5-lipoxygenase activator) 2q7r Homo sapiens Endoplasm. reticulum 3 12 30.3 ± 1.3 0 ± 1 -70.8
1.1.12.18. TrkH/TrkA potassium transport complex 4j9u Vibrio parahaemolyticus Bact. Gram-neg inner 2 20 29.4 ± 0.7 0 ± 0 -151.9
1.1.17.01. Ammonia channel, complex with inhibitory GlnK 2ns1 Escherichia coli Bact. Gram-neg inner 3 33 29.1 ± 0.7 0 ± 0 -148.7
1.1.12.18. TrkH/TrkA potassium transport complex, structure 1 4j7c Bacillus subtilis Bact. Gram-pos plas. 2 16 31.8 ± 1.0 0 ± 0 -165.6
1.2.43.02. E1/E2 envelope glycoprotein complex 2yew Barmah forest virus Viral 8 8 30.0 ± 0.8 0 ± 0 -53.5
1.1.01.01. Bacteriorhodopsin, from cubic phase 1ap9 Halobacterium salinarum Archaebac. 3 21 30.6 ± 1.2 0 ± 0 -97.8
1.1.01.01. Channelrhodopsin 2, structure 2 6eig Chlamydomonas reinhardtii Eukaryo. plasma 2 14 31.4 ± 0.8 0 ± 0 -107.3
1.1.12.01. Potassium channel KcsA, open deep-inactivated conformation 5vke Streptomyces lividans Bact. Gram-pos plas. 4 8 30.2 ± 0.6 0 ± 0 -104.9
1.1.10.01. ABC transporter BtuCD, nucleotide-bound state 4fi3 Escherichia coli Bact. Gram-neg inner 2 20 29.0 ± 1.0 0 ± 0 -118.3
1.2.01.01. Receptor tyrosine kinase EphA1, at pH 4.3 2k1k Homo sapiens Eukaryo. plasma 2 2 30.2 ± 1.5 0 ± 5 -43.3
1.1.10.03. Mitochondrial ABC transporter ABCB10, conformation 1 4ayt Homo sapiens Mitochon. inner 2 12 30.4 ± 0.8 0 ± 0 -79.7
1.3.24.01. Outer membrane protein ST50 5bun Salmonella enterica Bact. Gram-neg outer 3 12 23.8 ± 0.9 0 ± 0 -55.3
1.1.113.01. ERAD-associated E3 ubiquitin-protein ligase HRD1 5v6p Saccharomyces cerevisiae Endoplasm. reticulum 2 16 30.2 ± 2.0 0 ± 0 -48.4
1.1.12.04. Bacterial cyclic nucleotide regulated ion channel, different conformation 2zd9 Rhizobium loti Bact. Gram-neg inner 4 24 31.6 ± 1.2 0 ± 0 -192.8
1.1.12.02. Potassium channel Kv1.2., full-length 3lut Rattus norvegicus Eukaryo. plasma 4 24 25.1 ± 0.5 0 ± 0 -153.1
1.1.08.01. F-type Sodium ATPase 1yce Ilyobacter tartaricus Bact. Gram-neg inner 11 22 37.0 ± 0.5 0 ± 0 -104.0
1.3.32.01. Type II secretion system protein GspD, E. coli K12 5wq7 Escherichia coli Bact. Gram-neg outer 15 60 23.8 ± 0.6 0 ± 0 -257.6
1.1.14.01. Aquaporin Sopip2, closed state 2 3cll Spinacia oleracea Eukaryo. plasma 4 27 29.8 ± 0.7 0 ± 0 -127.8
1.1.06.01. Cytochrome b6f, structure 2 2d2c Mastigocladus laminosus Thylakoid 16 26 28.6 ± 0.6 0 ± 0 -156.9
1.1.14.01. Aquaporin-1, structure 1 1h6i Homo sapiens Eukaryo. plasma 4 32 30.8 ± 1.1 0 ± 0 -135.6
1.1.13.02. P2X purinoceptor 3, closed, antagonist-bound 5svr Homo sapiens Eukaryo. plasma 3 6 30.8 ± 1.1 0 ± 2 -32.4
1.1.12.03. Na-activated potassium channel Slo2.2, closed 5u76 Gallus gallus Eukaryo. plasma 4 24 31.0 ± 0.4 0 ± 0 -216.3
1.1.12.16. TRPML3 (Mucolipin-3) channel, structure 1 6aye Homo sapiens Lysosome 4 24 30.6 ± 0.4 0 ± 0 -209.7
1.1.31.01. Tellurite resistance protein tehA homolog 3m73 Haemophilus influenzae Bact. Gram-neg inner 3 30 29.1 ± 1.4 0 ± 0 -157.4
1.1.32.01. Excitatory amino acid transporter 1, structure 2 5mju Homo sapiens Eukaryo. plasma 3 36 29.8 ± 0.6 0 ± 0 -227.0
1.1.01.01. Halorhodopsin 1e12 Halobacterium salinarum Archaebac. 3 21 31.8 ± 1.4 0 ± 1 -126.7
1.1.16.01. Glutamate receptor 2, with antagonist, structure 2 4uqj Rattus norvegicus Eukaryo. plasma 4 12 33.6 ± 1.6 0 ± 0 -87.3
1.1.12.09. Voltage-gated sodium channel Nav1.7- NavAb, structure 1 3rvy Arcobacter butzleri Bact. Gram-neg inner 4 24 29.6 ± 0.4 0 ± 0 -216.9
1.1.97.01. Mycobacterial Insig homolog MvINS 4xu4 Mycobacterium vanbaalenii Bact. Gram-pos plas. 3 18 30.0 ± 0.9 0 ± 0 -122.0
1.1.35.02. Na+/H+ antiporter 1, outward-open conformation 4d0a Methanococcus jannaschii Archaebac. 2 26 28.4 ± 1.0 0 ± 0 -155.0
1.3.29.01. Bacterial amyloid secretion channel CsgG, structure 2 4uv3 Escherichia coli Bact. Gram-neg outer 9 36 26.4 ± 0.9 0 ± 0 -84.6
1.1.10.01. Hemin transport system permease, HmuU 4g1u Yersinia pestis Bact. Gram-neg inner 2 20 29.8 ± 0.5 0 ± 0 -114.3
1.1.12.12. K+ channel Eag1 (Kcnh1), with calmodulin 5k7l Rattus norvegicus Eukaryo. plasma 4 24 33.8 ± 0.6 0 ± 0 -272.0
1.1.67.01. Transmembrane protein 14C 2los Homo sapiens Mitochon. inner 1 3 26.8 ± 0.4 0 ± 2 -18.5
1.3.16.01. Porin 2 4d65 Providencia stuartii Bact. Gram-neg outer 3 48 24.4 ± 1.0 0 ± 0 -129.2
1.1.28.02. Efflux pump membrane transporter CmeB, structure 1 5lq3 Campylobacter jejuni Bact. Gram-neg inner 36 3 28.2 ± 0.6 0 ± 0 -186.7
1.1.06.01. Cytochrome bc1, mitochondrial 5xte Homo sapiens Mitochon. inner 12 26 29.0 ± 0.8 0 ± 0 -204.1
1.3.16.01. Outer membrane protein C 1osm Klebsiella pneumoniae Bact. Gram-neg outer 3 48 24.0 ± 1.1 0 ± 0 -136.6
1.1.02.03. Photosystem II 4yuu Cyanidium caldarium Thylakoid 34 70 32.2 ± 0.8 0 ± 0 -411.9
1.1.12.04. Bacterial cyclic nucleotide regulated ion channel 3beh Rhizobium loti Bact. Gram-neg inner 4 24 30.6 ± 0.8 0 ± 0 -205.7
1.1.26.04. Glycine betaine transporter BetP, asymmetric trimer, conformation 2 4doj Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 30.0 ± 0.6 0 ± 0 -186.4
1.3.23.01. Adhesin yadA 2lme Yersinia enterocolitica Bact. Gram-neg outer 3 15 23.4 ± 2.2 0 ± 1 -37.7
1.1.26.04. Glycine betaine transporter BetP, outward-open 4llh Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 29.8 ± 0.4 0 ± 0 -175.4
1.1.15.02. Proton-gated ion channel, conformation 7 5hcm Gloeobacter violaceus Bact. Gram-neg inner 5 20 32.0 ± 1.4 0 ± 0 -184.3
1.1.12.06. Calcium-activated cation channel 5cbg Tsukamurella paurometabola Bact. Gram-pos plas. 4 14 31.6 ± 0.8 0 ± 0 -77.0
1.1.21.01. CorA magnesium transporter, complete loops, structure 3 5jrw Thermotoga maritima Bact. Gram-neg inner 5 10 31.0 ± 0.6 0 ± 0 -80.2
1.1.21.01. CorA magnesium transporter, complete loops, structure 1 4i0u Thermotoga maritima Bact. Gram-neg inner 5 10 30.4 ± 1.1 0 ± 0 -83.4
1.1.20.01. Connexin 26 gap junction channel, structure 2 5er7 Homo sapiens Eukaryo. plasma 6 24 31.4 ± 0.7 0 ± 0 -174.7
1.1.08.01. F1F0 ATP synthase, F0 complex 3zk1 Fusobacterium nucleatum Bact. Gram-neg inner 11 22 36.6 ± 2.3 0 ± 0 -84.3
1.3.25.03. Hemolytic lectin CEL-III 3w9t Cucumaria echinata (Sea cucumber) Secreted 7 14 33.8 ± 0.8 0 ± 0 -82.6
1.1.10.03. Antibacterial peptide transporter McjD, outward occluded state 4pl0 Escherichia coli Bact. Gram-neg inner 2 12 32.4 ± 0.8 0 ± 0 -107.2
1.1.26.03. Sodium/sugar symporter vSGLT, substrate-bound 3dh4 Vibrio parahaemolyticus Bact. Gram-neg inner 2 30 30.0 ± 0.7 0 ± 0 -184.0
1.1.06.01. Cytochrome bc1, bacterial 1zrt Rhodobacter capsulatus Bact. Gram-neg inner 6 20 29.9 ± 0.9 0 ± 0 -178.6
1.1.16.01. Glutamate receptor 2, with TARP channel, structure 3 5vou Rattus norvegicus Eukaryo. plasma 8 20 32.2 ± 0.8 0 ± 0 -232.0
1.1.01.01. Archaerhodopsin-2, trimeric 2ei4 Halobacterium sp. Archaebac. 3 21 30.5 ± 1.2 0 ± 1 -143.9
1.1.07.01. Mitochondrial cytochrome c oxidase 2dyr Bos taurus Mitochon. inner 20 56 28.0 ± 0.6 0 ± 0 -198.1
1.1.12.04. Cyclic nucleotide-gated ion Channel 5v4s Leptospira licerasiae Bact. Gram-neg inner 4 24 31.0 ± 0.2 0 ± 0 -223.4
1.1.14.01. Aquaporin-5 3d9s Homo sapiens Eukaryo. plasma 4 32 30.3 ± 0.9 0 ± 0 -133.3
1.1.12.09. Voltage-gated sodium channel NavAb, structure 2 4ekw Arcobacter butzleri Bact. Gram-neg inner 4 24 29.4 ± 0.5 0 ± 0 -201.0
1.1.13.01. Acid-sensitive ion channel 1, at low pH 4nyk Gallus gallus Eukaryo. plasma 3 6 28.2 ± 1.1 0 ± 1 -38.3
1.1.08.01. F1F0 ATP synthase, F0F1 complex 5fl7 Yarrowia lipolytica Mitochon. inner 10 20 38.0 ± 0.6 0 ± 0 -92.3
1.3.22.01. VDAC-1 channel, dimer 5xdo Homo sapiens Mitochon. outer 2 38 23.0 ± 0.4 0 ± 0 -95.1
1.3.32.01. Type II secretion system protein GspD 5wq8 Vibrio cholerae Bact. Gram-neg outer 15 60 19.4 ± 0.0 0 ± 0 -231.2
1.1.13.02. Invertebrate P2X receptor 5f1c Amblyomma maculatum Eukaryo. plasma 3 6 31.0 ± 1.4 0 ± 0 -69.4
1.1.06.01. Cytochrome b6f, structure 3 4h13 Mastigocladus laminosus Thylakoid 16 26 31.6 ± 0.6 0 ± 0 -219.6
1.1.12.09. Sodium channel NavMs, open state 2 3zjz Magnetococcus marinus Bact. Gram-neg inner 4 8 29.8 ± 1.8 0 ± 1 -61.1
1.1.14.01. Aquaporin Sopip2, closed state 1z98 Spinacia oleracea Eukaryo. plasma 4 32 28.1 ± 2.2 0 ± 0 -117.2
1.1.12.04. Nucleotide-gated channel 1, HCN1, structure 1 5u6o Homo sapiens Eukaryo. plasma 4 24 33.0 ± 0.8 0 ± 0 -238.4
1.1.73.01. Outer membrane complex of type IV secretion system (VirB7/VirB9/VirB10 complex) 3jqo Escherichia coli Bact. Gram-neg outer 14 14 22.6 ± 0.6 0 ± 0 -67.4
1.1.12.16. TRPML3 (Mucolipin-3) channel, structure 2 6ayf Homo sapiens Lysosome 4 24 31.4 ± 0.6 0 ± 0 -192.9
1.1.12.09. Voltage-gated sodium channel 4bgn Caldalkalibacillus thermarum Bact. Gram-pos plas. 4 24 27.0 ± 0.3 0 ± 0 -201.5
1.1.84.01. Phosphatidylinositolphosphate synthase, structure 1 5d92 Renibacterium salmoninarum Bact. Gram-pos plas. 2 12 31.8 ± 1.4 0 ± 1 -98.3
1.1.76.01. Acid-activated urea channel 3ux4 Helicobacter pylori Bact. Gram-neg inner 6 36 30.0 ± 0.5 0 ± 0 -190.2
1.1.14.01. Aquaporin AQY1 2w2e Pichia pastoris Eukaryo. plasma 4 32 30.2 ± 0.8 0 ± 0 -131.7
1.1.10.03. Mitochondrial ABC transporter ABCB10, conformation 3 4ayx Homo sapiens Mitochon. inner 2 12 30.0 ± 0.6 0 ± 0 -76.8
1.3.22.01. VDAC-1 channel, structure 1 2jk4 Homo sapiens Mitochon. outer 1 19 23.4 ± 2.3 0 ± 1 -40.0
1.1.104.01. TRIC cation channel 5wuf Colwellia psychrerythraea Bact. Gram-neg inner 3 21 30.2 ± 0.8 0 ± 0 -112.5
1.1.14.01. Aquaporin-0, alternative packing with lipids 3m9i Ovis aries Eukaryo. plasma 4 24 27.6 ± 1.4 0 ± 0 -139.0
1.1.01.02. Opsin, active, retinal-free state, dimer 3cap Bos taurus Eukaryo. plasma 2 14 30.8 ± 1.1 0 ± 0 -130.1
1.3.16.01. Anion-selective porin 2fgq Comamonas acidovorans Bact. Gram-neg outer 3 48 25.0 ± 0.9 0 ± 0 -130.8
1.1.14.01. Aquaporin-0, complex with calmodulin 3j41 Ovis aries Eukaryo. plasma 4 24 29.6 ± 0.9 0 ± 0 -129.7
1.1.02.03. PSII-LHCII supercomplex 3jcu Spinacia oleracea Thylakoid 42 100 30.8 ± 0.0 0 ± 0 -385.6
1.1.12.13. Potassium channel Kirbac3.1, open conformation 2 4lp8 Magnetospirillum magnetotacticum Bact. Gram-neg inner 4 8 29.2 ± 0.8 0 ± 0 -89.2
1.1.01.02. Opioid kappa receptor 4djh Homo sapiens Eukaryo. plasma 2 14 32.0 ± 0.8 1 ± 0 -146.6
1.1.51.01. Vitamin K epoxide reductase, conformation 1 4nv6 Synechococcus sp. Bact. Gram-neg inner 1 5 29.8 ± 1.8 1 ± 1 -54.2
1.1.01.04. Smoothened homolog, dimer, structure 2 4qin Homo sapiens Eukaryo. plasma 2 14 31.6 ± 1.3 1 ± 1 -94.0
1.1.12.09. Sodium channel NavMs, open state 1 4f4l Magnetococcus marinus Bact. Gram-neg inner 4 8 28.2 ± 1.3 1 ± 0 -74.6
1.1.09.01. Copper efflux ATPase, CopA, alternative conformation 3j09 Archaeoglobus fulgidus Archaebac. 2 16 27.0 ± 0.1 1 ± 0 -23.5
1.1.23.01. TMEM16 lipid scramblase 4wis Nectria haematococca Eukaryo. plasma 2 20 29.8 ± 0.9 1 ± 1 -99.7
1.1.35.02. Na+/H+ antiporter, structure 2 4cz9 Pyrococcus abyssi Archaebac. 2 26 27.2 ± 0.8 1 ± 0 -116.9
1.1.12.15. Ryanodine receptor 1, closed structure 1 5gky Oryctolagus cuniculus Endoplasm. reticulum 4 24 30.8 ± 0.0 1 ± 0 -174.0
1.1.02.03. PSII-LHCII supercomplex 5mdx Arabidopsis thaliana Thylakoid 48 122 29.4 ± 0.4 1 ± 0 -609.5
1.1.02.04. LH1-RC complex, C2 form 3wmm Thermochromatium tepidum Bact. Gram-neg inner 35 43 35.8 ± 0.0 1 ± 0 -254.6
1.1.43.01. Saccharide transporter, EIIC (ChbC), inward-facing 3qnq Bacillus cereus Bact. Gram-pos plas. 2 20 29.6 ± 1.0 1 ± 0 -140.6
1.1.10.01. ABC transporter BtuCD, a nucleotide-bound outward facing state 4r9u Escherichia coli Bact. Gram-neg inner 2 20 28.6 ± 1.3 1 ± 1 -119.8
1.2.43.01. Envelope glycoprotein, Dengue virus type 1 3g7t Dengue virus Viral 3 0 5.9 ± 0.9 1 ± 3 -12.2
1.1.10.03. Type-1 secretion system ABC transporter (HlyB-like) 5l22 Aquifex aeolicus Bact. Gram-neg inner 2 12 33.0 ± 1.4 1 ± 0 -111.8
1.1.34.01. Mitochondrial ADP-ATP carrier, conformation 1 4c9g Saccharomyces cerevisiae Mitochon. inner 1 6 31.4 ± 1.5 1 ± 1 -54.6
1.1.10.02. Methionine importer MetNI, conformation 1 3tui Escherichia coli Bact. Gram-neg inner 2 10 30.2 ± 1.3 1 ± 1 -81.0
1.1.08.01. F1F0 ATP synthase, F0 complex, conformation 2 3zo6 Bacillus pseudofirmus Bact. Gram-pos plas. 12 24 39.6 ± 1.1 1 ± 0 -130.6
1.1.12.12. Potassium channel hERG, KCNH2 5va1 Homo sapiens Eukaryo. plasma 4 24 30.8 ± 0.1 1 ± 0 -151.2
1.1.55.01. Bacterial polysaccharide co-polymerase FepE 3b8n Escherichia coli Bact. Gram-neg inner 9 0 1.6 ± 0.1 1 ± 0 -20.3
1.1.10.04. P-glycoprotein, inward-facing conformation 7 5ko2 Mus musculus Eukaryo. plasma 1 12 33.0 ± 1.0 1 ± 1 -102.4
1.3.14.01. Toluene transporter TbuX 3bry Ralstonia pickettii Bact. Gram-neg outer 1 14 25.4 ± 1.5 1 ± 2 -57.7
1.1.12.18. Potassium uptake protein TrkH 3pjz Vibrio parahaemolyticus Bact. Gram-neg inner 2 20 29.7 ± 0.6 1 ± 0 -164.0
1.2.43.03. Envelope glycoprotein B 3nw8 Human herpesvirus Viral 3 0 4.6 ± 0.0 1 ± 1 -11.7
1.1.15.01. GLIC-GABAAR alpha1 chimera, structure 2 5osc Mus musculus Eukaryo. plasma 5 20 31.4 ± 0.4 1 ± 0 -138.4
1.1.64.01. Sodium/calcium exchanger, structure 2 3v5s Methanococcus jannaschii Archaebac. 1 10 29.6 ± 1.6 1 ± 2 -75.1
1.1.08.01. V-type proton ATPase, vacuolar, state 1 3j9t Saccharomyces cerevisiae Vacuole 10 40 39.6 ± 1.3 1 ± 0 -169.3
1.3.19.01. Pyroglutamate porin OpdO 2y0k Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.8 ± 1.2 1 ± 0 -55.8
1.2.01.01. Vascular endothelial growth factor receptor 2 (759-795), homotrimer 2met Homo sapiens Eukaryo. plasma 3 3 31.8 ± 1.5 1 ± 1 -331.1
1.1.81.01. P7 viral protein 2m6x Hepatitis C virus Endoplasm. reticulum 6 12 26.8 ± 0.1 1 ± 0 -35.4
1.1.11.01. Protein translocase Sec61, with signal peptide 3jc2 Canis lupus familiaris Endoplasm. reticulum 13 4 28.8 ± 1.3 1 ± 0 -73.0
1.1.25.06. D-xylose-proton symporter xylE, conformation 1 4gc0 Escherichia coli Bact. Gram-neg inner 1 12 30.2 ± 0.9 1 ± 0 -90.2
1.1.16.01. Glutamate receptor 2, with partial agonist, structure 3 4u1w Rattus norvegicus Eukaryo. plasma 4 12 30.8 ± 0.9 1 ± 0 -92.7
1.1.26.04. Glycine betaine transporter BetP, inward-facing conformation 4c7r Corynebacterium glutamicum Bact. Gram-pos plas. 3 39 30.0 ± 0.7 1 ± 0 -186.7
1.1.83.01. TspO protein, structure 1 4uc1 Rhodobacter sphaeroides Bact. Gram-neg outer 2 10 29.6 ± 1.3 1 ± 1 -70.6
1.1.02.06. Light-Harvesting Complex II-CP24 complex 5xno Pisum sativum Thylakoid 4 12 27.0 ± 1.4 1 ± 0 -127.8
1.1.10.04. P-glycoprotein, inward-facing conformation 6 5kpi Mus musculus Eukaryo. plasma 1 12 31.8 ± 1.6 1 ± 1 -95.8
1.1.01.02. Orexin receptor type 2 5wqc Homo sapiens Eukaryo. plasma 1 7 31.4 ± 1.6 1 ± 1 -73.4
1.1.28.01. AcrABZ-TolC multidrug efflux pump 5o66 Escherichia coli Bact. Gram-neg inner 6 39 28.6 ± 0.4 1 ± 0 -203.4
1.1.10.02. Methionine importer MetNI, conformation 3 3dhw Escherichia coli Bact. Gram-neg inner 2 10 29.2 ± 1.0 1 ± 0 -82.5
1.1.26.08. Boron transporter 1 5sv9 Saccharomyces mikatae Eukaryo. plasma 2 28 33.6 ± 0.6 1 ± 0 -177.0
1.2.01.01. Fibroblast growth factor receptor 3, peptide 357-399 2lzl Homo sapiens Eukaryo. plasma 2 2 30.0 ± 4.2 1 ± 3 -28.8
1.1.12.01. Potassium channel KcsA, full length, open 3pjs Streptomyces lividans Bact. Gram-pos plas. 4 8 31.6 ± 1.2 1 ± 1 -87.3
1.3.21.01. Outer membrane usher protein FimD, complex with FimC-FimF-FimG-FimH 4j3o Escherichia coli Bact. Gram-neg outer 1 24 23.8 ± 1.4 1 ± 1 -52.9
1.1.01.02. Histamine H1 receptor 3rze Homo sapiens Eukaryo. plasma 1 7 32.0 ± 1.4 1 ± 1 -72.4
1.2.01.01. Epidermal growth factor receptor, erbB-1, homodimer (634-676) 5lv6 Homo sapiens Eukaryo. plasma 2 2 32.4 ± 1.4 1 ± 0 -48.8
1.1.10.02. Molybdate transporter ModBC, open state 3d31 Methanosarcina acetivorans Archaebac. 2 12 29.8 ± 1.5 1 ± 0 -91.6
1.1.01.01. Halorhodopsin 3a7k Natronomonas pharaonis Archaebac. 3 21 33.8 ± 1.4 1 ± 0 -141.3
1.1.01.02. Muscarinic acetylcholine receptor M3, structure 2 4u15 Rattus norvegicus Eukaryo. plasma 1 7 31.8 ± 1.5 1 ± 1 -70.6
1.1.83.01. TspO protein, structure 2 4uc2 Rhodobacter sphaeroides Bact. Gram-neg outer 2 10 30.4 ± 0.9 1 ± 0 -79.2
1.3.20.01. Ferric enterobactin receptor PirA 5fr8 Acinetobacter baumannii Bact. Gram-neg outer 1 22 23.4 ± 0.8 1 ± 0 -65.3
1.1.15.02. Proton-gated ion channel, resting state 4npq Gloeobacter violaceus Bact. Gram-neg inner 5 20 33.8 ± 2.1 1 ± 0 -185.4
1.1.13.02. P2X purinoceptor 5xw6 Gallus gallus Eukaryo. plasma 3 6 31.0 ± 0.6 1 ± 0 -79.8
1.1.35.01. Sodium/proton antiporter 1 (NhaA), dimer, different conformation 4atv Escherichia coli Bact. Gram-neg inner 2 24 28.6 ± 1.3 1 ± 0 -154.7
1.1.18.01. Mechanosensitive channel MscL, expanded state 3hzq Staphylococcus aureus Bact. Gram-pos plas. 4 8 20.8 ± 1.2 1 ± 0 -56.9
1.1.36.01. CLC-K chloride channel, structure 2 5tr1 Bos taurus Eukaryo. plasma 2 28 31.4 ± 1.0 1 ± 0 -135.2
1.3.19.01. BenF-like porin 3jty Pseudomonas fluorescens Bact. Gram-neg outer 1 18 24.2 ± 1.2 1 ± 0 -59.8
1.1.103.01. ExbB/ExbD complex, structure 1 5sv0 Escherichia coli Bact. Gram-neg inner 5 15 31.8 ± 0.8 1 ± 1 -102.1
1.1.115.01. MlaA protein, with OMPF (E. coli) 5nuq Serratia marcescens Bact. Gram-neg outer 4 50 23.8 ± 0.2 1 ± 0 -148.6
1.1.10.01. ABC transporter permease HI1471 2nq2 Haemophilus influenzae Bact. Gram-neg inner 2 20 31.9 ± 0.9 1 ± 1 -124.2
1.1.12.16. Polycystin-2 channel, structure 2 5mke Homo sapiens Eukaryo. plasma 4 24 25.8 ± 0.0 1 ± 0 -168.9
1.1.14.02. Formate transporter 1, FocA 3kly Vibrio cholerae Bact. Gram-neg inner 5 35 31.4 ± 0.5 1 ± 0 -188.2
1.2.43.01. Envelope glycoprotein 1urz Tick-borne encephalitis virus Viral 3 0 5.9 ± 0.9 1 ± 8 -10.3
1.1.16.01. Glutamate receptor 2, with auxiliary subunit GSG1L, structure 3 5wek Rattus norvegicus Eukaryo. plasma 4 20 33.0 ± 1.4 1 ± 0 -162.4
3.1.07.02. gp41-M-MAT, a membrane associated MPER trimer 2lp7 Human immunodeficiency virus type 1 Viral 3 3 26.8 ± 0.9 1 ± 1 -14.2
1.1.19.01. Mechanosensitive channel protein MscS, expanded state 2oau Escherichia coli Bact. Gram-neg inner 7 14 31.8 ± 0.8 1 ± 1 -171.3
1.3.24.01. Cation efflux system protein CusC 3pik Escherichia coli Bact. Gram-neg outer 3 12 24.3 ± 1.2 1 ± 0 -33.8
1.1.16.01. Glutamate receptor 2, with conotoxin, structure 2 4u5c Rattus norvegicus Eukaryo. plasma 4 12 31.4 ± 1.1 1 ± 1 -95.7
1.2.01.01. Receptor tyrosine kinase erbB-2, dimer, structure 3 5ob4 Homo sapiens Eukaryo. plasma 2 2 27.3 ± 3.0 1 ± 1 -28.6
1.1.05.01. Polysulfide reductase, inactive state 2vpz Thermus thermophilus Bact. Gram-neg inner 2 16 29.8 ± 1.5 1 ± 0 -105.2
1.3.20.01. SusD-SusC complex, a dimer 5t4y Bacteroides thetaiotaomicron Bact. Gram-neg outer 2 44 25.0 ± 0.8 1 ± 0 -137.7
1.1.90.01. Phosphatidate cytidylyltransferase, conformation 1 4q2e Thermotoga maritima Bact. Gram-neg inner 2 18 29.8 ± 0.6 1 ± 0 -77.7
1.1.21.01. CorA magnesium transporter, structure 2 4eeb Thermotoga maritima Bact. Gram-neg inner 5 10 30.0 ± 1.0 1 ± 1 -81.6
1.1.27.01. Ferrous-iron efflux pump fieF, different conformation 2qfi Escherichia coli Bact. Gram-neg inner 2 12 25.0 ± 1.3 1 ± 2 -32.4
1.2.23.01. M2 proton channel, influenza A and B hydrid 2ljb Influenza virus Viral 4 4 31.6 ± 1.6 1 ± 1 -51.3
1.1.104.01. Trimeric intracellular cation channel, structure 2 5egi Caenorhabditis elegans Endoplasm. reticulum 3 21 30.8 ± 0.0 1 ± 0 -54.9
1.1.01.01. Blue-light absorbing proteorhodopsin 4knf Gamma-proteobacterium Bact. Gram-neg inner 5 35 28.4 ± 1.5 1 ± 1 -159.6
1.3.20.01. Ferric enterobactin receptor FepA 1fep Escherichia coli Bact. Gram-neg outer 1 22 24.3 ± 1.1 1 ± 0 -77.2
1.1.12.14. Mechanotransduction channel NOMPC 5vkq Drosophila melanogaster Eukaryo. plasma 4 24 30.6 ± 0.6 1 ± 0 165.5
1.1.01.01. Bacteriorhodopsin 5jsi Candidatus Actinomarina minuta Bact. Gram-pos plas. 2 14 25.8 ± 0.6 1 ± 1 -71.9
1.1.02.02. Photosystem I of plants 4rku Pisum sativum Thylakoid 13 45 31.8 ± 1.0 1 ± 0 -346.8
1.1.10.03. ABC-type bacteriocin transporter 4ry2 Clostridium thermocellum Bact. Gram-pos plas. 2 12 33.8 ± 0.2 1 ± 0 -109.4
1.1.02.02. Photosystem I of cyanobacteria 1jb0 Thermosynechococcus elongatus Thylakoid 9 32 31.4 ± 0.4 1 ± 0 -285.7
1.1.105.01. CD81 antigen 5tcx Homo sapiens Eukaryo. plasma 1 4 34.2 ± 2.4 1 ± 1 -55.9
1.1.10.03. Oligosaccharide flippase PglK, inward-open, structure 2 5c76 Campylobacter jejuni Bact. Gram-neg inner 2 12 32.0 ± 0.8 1 ± 0 -120.5
1.1.15.02. Proton-gated ion channel, inactive conformation 6 5sxv Erwinia chrysanthemi Bact. Gram-neg inner 5 20 30.6 ± 0.6 1 ± 0 -100.4
1.1.041.01. Bacterial semiSWEET transporter, outward-open conformation 4x5n Escherichia coli Bact. Gram-neg inner 2 6 36.8 ± 1.1 1 ± 3 -70.5
1.3.20.01. Ferric enterobactin receptor PirA 5fp2 Pseudomonas aeruginosa Bact. Gram-neg outer 1 22 22.0 ± 1.2 1 ± 0 -71.0
1.2.44.01. Amyloid beta A4 protein, 686-726, dimer, structure 1 2loh Homo sapiens Eukaryo. plasma 2 2 32.8 ± 1.6 1 ± 1 -34.1
1.1.06.01. Cytochrome bc1, mitochondrial 1ezv Saccharomyces cerevisiae Mitochon. inner 24 10 27.5 ± 0.6 1 ± 0 -170.6
1.1.01.05. Metabotropic glutamate receptor 1 4or2 Homo sapiens Eukaryo. plasma 2 14 31.4 ± 0.9 1 ± 0 -117.3
1.1.35.02. Na+/H+ antiporter 1, inward-open conformation 4czb Methanococcus jannaschii Archaebac. 26 26 27.2 ± 0.5 1 ± 0 -128.3
1.1.02.04. Reaction center-LH1-PufX dimer complex, unit 1 4jcb Rhodobacter sphaeroides Bact. Gram-neg inner 32 40 28.0 ± 0.5 1 ± 0 -127.0
1.1.28.01. Multidrug efflux transporter AcrB, asymmetric 2gif Escherichia coli Bact. Gram-neg inner 3 36 29.0 ± 0.2 1 ± 0 -187.5
1.1.28.01. Multidrug efflux transporter AcrB, asymmetric, complex with ankyrin repeat 1 4dx5 Escherichia coli Bact. Gram-neg inner 3 36 27.4 ± 0.7 1 ± 0 -181.0
1.1.15.02. Proton-gated ion channel, inactive conformation 7 5sxu Erwinia chrysanthemi Bact. Gram-neg inner 5 20 30.2 ± 0.8 1 ± 0 -100.5
1.3.24.01. Outer membrane protein OprJ 5azs Pseudomonas aeruginosa Bact. Gram-neg outer 3 12 23.4 ± 0.8 1 ± 1 -55.3
1.2.49.01. Tumor necrosis factor receptor 6 2na7 Homo sapiens Eukaryo. plasma 3 3 26.8 ± 0.6 1 ± 1 -33.2
1.1.24.01. Bestrophin-1 5x87 Klebsiella pneumoniae Bact. Gram-neg inner 5 20 31.0 ± 2.4 1 ± 0 -120.3
1.1.88.01. NAD(P) transhydrogenase, structure 2 4o9u Thermus thermophilus Bact. Gram-neg inner 4 24 30.6 ± 1.1 1 ± 0 -150.7
1.1.16.01. Glutamate receptor 2, with TARP channel, structure 2 5vot Rattus norvegicus Eukaryo. plasma 8 20 31.4 ± 1.2 1 ± 0 -222.9
1.1.28.01. Multidrug efflux transporter AcrB-AcrZ complex, structure 2 5nc5 Escherichia coli Bact. Gram-neg inner 6 39 29.8 ± 0.6 1 ± 0 -215.8
1.1.69.01. HIG1 domain family member 1A 2lom Homo sapiens Eukaryo. plasma 1 2 22.0 ± 5.0 1 ± 1 -27.3
1.1.25.06. D-xylose-proton symporter xylE, conformation 4 4qiq Escherichia coli Bact. Gram-neg inner 1 12 29.8 ± 1.8 1 ± 1 -72.6
1.3.22.01. VDAC-1 channel, structure 2 (NMR) 2k4t Homo sapiens Mitochon. outer 1 19 22.0 ± 1.5 1 ± 1 -34.8
1.1.02.04. Reaction center-LH1-PufX dimer complex, unit 2 4jc9 Rhodobacter sphaeroides Bact. Gram-neg inner 32 40 28.4 ± 0.7 1 ± 0 -126.6
1.1.26.04. Glycine betaine transporter BetP, alternative inward-facing open conformation 3p03 Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 29.8 ± 0.7 1 ± 0 -160.9
1.1.01.02. Adenosine receptor A1 5uen Homo sapiens Eukaryo. plasma 2 14 32.2 ± 1.0 1 ± 0 -145.8
1.2.23.01. M2 proton channel of Influenza A, S31N, NMR structure 2n70 Influenza virus Viral 4 4 29.8 ± 1.7 1 ± 0 -65.3
1.1.10.03. Mitochondrial ABC transporter ABCB10, conformation 4 3zdq Homo sapiens Mitochon. inner 2 12 30.8 ± 0.5 1 ± 0 -71.8
1.1.21.01. Zinc transport protein ZntB 5n9y Escherichia coli Bact. Gram-neg inner 5 10 30.2 ± 1.0 1 ± 0 -60.5
1.1.01.02. Thrombin (proteinase-activated) receptor 1, PAR1 3vw7 Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.9 1 ± 0 -72.2
1.1.16.01. Glutamate receptor 2, with TARP channel, structure 1 5kk2 Rattus norvegicus Eukaryo. plasma 8 32 34.0 ± 0.4 1 ± 0 -123.2
1.1.16.01. GluN1/GluN2A/GluN2B NMDA receptor, structure 2 5up2 Xenopus laevis Eukaryo. plasma 4 12 31.0 ± 0.6 1 ± 0 -111.8
1.3.14.01. Fatty Acid Transporter FadL, F3E, open channel 3pgu Escherichia coli Bact. Gram-neg outer 1 14 25.2 ± 1.5 1 ± 1 -51.5
1.1.12.09. Voltage-gated sodium channel NavAb, structure 3 5klb Arcobacter butzleri Bact. Gram-neg inner 4 24 30.8 ± 0.3 1 ± 0 -218.3
1.2.26.01. Outer membrane lipoprotein Wza, water-soluble part 2w8h Escherichia coli Bact. Gram-neg outer 8 0 1.6 ± 0.2 1 ± 0 -22.1
1.1.06.02. Ascorbate-dependent oxidoreductase 4o6y Arabidopsis thaliana Eukaryo. plasma 2 12 31.0 ± 1.3 1 ± 0 -97.6
1.1.10.01. Heme importer BhuUV 5b57 Burkholderia cepacia Bact. Gram-neg inner 2 20 28.6 ± 0.8 1 ± 1 -85.4
1.1.25.02. Lactose permease LacY, structure 6 5gxb Escherichia coli Bact. Gram-neg inner 1 12 33.8 ± 1.5 1 ± 1 -89.6
1.1.25.01. Glycerol-3-phosphate transporter glpT 1pw4 Escherichia coli Bact. Gram-neg inner 1 12 31.2 ± 1.4 1 ± 7 -92.5
1.3.15.02. CymA protein, conformation 1 4d51 Klebsiella oxytoca Bact. Gram-neg outer 1 14 25.0 ± 1.7 2 ± 1 -44.8
1.1.54.01. Diacylglycerol kinase (DAGK), conformation 1 3ze5 Escherichia coli Bact. Gram-neg inner 3 9 29.8 ± 0.9 2 ± 1 -72.5
1.1.57.03. Gamma-secretase complex, structure 6 5fn5 Homo sapiens Endoplasm. reticulum 4 17 30.2 ± 1.2 2 ± 1 -134.8
1.1.110.01. Apolipoprotein N-acyl transferase, structure 3 5vrg Escherichia coli Bact. Gram-neg inner 1 8 30.2 ± 1.2 2 ± 1 -70.7
1.1.35.01. Sodium/proton antiporter 1 (NhaA) 1zcd Escherichia coli Bact. Gram-neg inner 1 14 28.4 ± 1.4 2 ± 2 -78.6
1.1.14.01. Aquaporin Sopip2, open state 2b5f Spinacia oleracea Eukaryo. plasma 4 32 29.4 ± 1.1 2 ± 2 -113.0
1.1.12.08. Voltage-dependent calcium channel, structure 3 5gjw Oryctolagus cuniculus Eukaryo. plasma 2 28 31.6 ± 0.6 2 ± 0 -185.6
2.1.34.01. Septium site-determining protein DivIVA 2wuj Bacillus subtilis Bact. Gram-pos plas. 2 0 4.0 ± 1.8 2 ± 18 -5.4
1.3.19.01. Porin OpdQ 3t24 Pseudomonas aeruginosa Bact. Gram-neg outer 1 18 23.0 ± 1.3 2 ± 0 -56.5
1.1.26.08. Band 3 anion transport protein, SLC4A1 4yzf Homo sapiens Eukaryo. plasma 2 28 31.8 ± 1.0 2 ± 0 -201.4
1.1.10.04. P-glycoprotein, inward-facing conformation 1b 4lsg Mus musculus Eukaryo. plasma 1 12 31.0 ± 8.0 2 ± 0 -85.3
1.1.01.02. Viral GPCR US28, complex with fractalkine 4xt3 Human herpesvirus Eukaryo. plasma 1 7 32.8 ± 1.7 2 ± 2 -69.1
1.1.65.01. Concentrative nucleoside transporter, intermediate 1 state 5l27 Neisseria wadsworthii Bact. Gram-neg inner 3 24 27.8 ± 1.2 2 ± 0 -166.9
1.1.28.03. SecDF secretion protein, structure 3 5xap Deinococcus radiodurans Bact. Gram-neg inner 1 12 30.2 ± 0.8 2 ± 1 -97.2
1.1.01.02. Beta-1 adrenergic receptor, inactive, complex with antagonist 2ycw Meleagris gallopavo Eukaryo. plasma 1 7 32.2 ± 1.3 2 ± 0 -77.8
1.1.94.01. Ascorbate-specific permease IIC component UlaA, structure 2 4rp9 Escherichia coli Bact. Gram-neg inner 2 22 29.8 ± 0.6 2 ± 0 -141.1
1.1.12.07. Potassium channel subfamily K member 2 5vkn Mus musculus Eukaryo. plasma 2 8 30.2 ± 0.6 2 ± 0 -100.0
1.1.35.01. Sodium/proton antiporter 1 (NhaA), dimer 3fi1 Escherichia coli Bact. Gram-neg inner 2 24 28.4 ± 1.6 2 ± 1 -126.7
1.1.02.02. Photosystem I of cyanobacteria, virus-like, structure 2 4l6v Synechocystis sp. Thylakoid 7 32 31.8 ± 0.2 2 ± 0 -269.6
1.1.12.09. Sodium channel BacNaV 4lto Alkalilimnicola ehrlichei Bact. Gram-neg inner 4 8 30.6 ± 1.1 2 ± 1 -97.3
1.1.25.02. Lactose permease LacY, structure 5 4oaa Escherichia coli Bact. Gram-neg inner 1 12 32.6 ± 1.6 2 ± 2 -101.7
1.1.02.01. Photosynthetic reaction center 2j8c Rhodobacter sphaeroides Bact. Gram-neg inner 3 11 31.8 ± 0.8 2 ± 0 -129.6
1.1.83.01. Bacterial translocator protein, dimer 4ryi Bacillus cereus Bact. Gram-pos plas. 2 10 30.4 ± 1.2 2 ± 0 -89.7
1.1.65.01. Concentrative nucleoside transporter, intermediate 3 state 5u9w Neisseria wadsworthii Bact. Gram-neg inner 3 24 29.0 ± 0.2 2 ± 0 -155.3
1.1.36.01. ClC chloride transporter 1kpl Salmonella enterica Bact. Gram-neg inner 2 28 29.3 ± 0.8 2 ± 1 -128.0
1.2.10.01. Glycophorin A, crystal structure 5eh4 Homo sapiens Eukaryo. plasma 2 2 29.8 ± 1.4 2 ± 1 -38.0
1.3.20.01. Bacterial Zn-transporter ZnuD, structure 1 4rdr Neisseria meningitidis Bact. Gram-neg outer 1 22 23.2 ± 0.9 2 ± 0 -70.1
2.2.34.05. Tachystatin-B2 2dcw Tachypleus tridentatus (Japanese horseshoe crab) Secreted 1 0 3.4 ± 0.8 2 ± 6 -10.1
1.1.12.07. Potassium channel subfamily K member 2 4twk Homo sapiens Eukaryo. plasma 2 8 29.4 ± 0.8 2 ± 0 -107.6
1.1.02.06. Light-harvesting complex CP29 3pl9 Spinacia oleracea Thylakoid 1 3 29.8 ± 1.6 2 ± 2 -66.6
1.1.05.04. Fumarate reductase 2bs2 Wolinella succinogenes Bact. Gram-neg inner 2 10 31.4 ± 1.3 2 ± 0 -118.8
1.1.39.03. ECF transporter, S-component 5d0y Lactobacillus delbrueckii Bact. Gram-pos plas. 1 6 29.8 ± 1.8 2 ± 2 -55.7
1.1.83.01. TspO protein, structure 3 4uc3 Rhodobacter sphaeroides Bact. Gram-neg outer 2 10 29.4 ± 1.5 2 ± 1 -67.1
1.1.02.01. Photosynthetic reaction center, complex with cytochrome c 1eys Thermochromatium tepidum Bact. Gram-neg inner 3 11 31.6 ± 1.0 2 ± 0 -116.0
1.1.10.06. ABCA1 transporter 5xjy Homo sapiens Eukaryo. plasma 1 12 31.0 ± 1.0 2 ± 0 -88.0
1.1.01.01. Sensory rhodopsin, trimer 2m3g Nostoc sp. Bact. Gram-neg inner 3 21 31.8 ± 0.8 2 ± 0 -132.8
1.1.103.01. ExbB/ExbD complex, structure 2 5sv1 Escherichia coli Bact. Gram-neg inner 6 16 30.8 ± 0.5 2 ± 0 -109.5
1.1.06.01. Cytochrome bc1, mitochondrial, structure 3 1pp9 Bos taurus Mitochon. inner 10 24 29.8 ± 0.4 2 ± 0 -179.7
1.1.108.01. Nitrate/nitrite sensor histidine kinase NarQ, structure 3 5jeq Escherichia coli Bact. Gram-neg inner 2 4 31.8 ± 1.4 2 ± 1 -60.1
1.1.60.01. Protease GlpG, crystallographic trimer