PDB ID or protein name

Homo sapiens (443 proteins)

Family Protein Name PDB ID Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
1.2.01.01. Epidermal growth factor receptor, erbB-1, homodimer (642-697) 2m20 Eukaryo. plasma 2 2 34.0 ± 3.0 0 ± 3 -52.5
1.3.22.01. VDAC-1 channel 2jk4 Mitochon. outer 1 19 23.4 ± 2.3 0 ± 1 -40.0
1.1.14.01. Aquaporin-5 3d9s Eukaryo. plasma 4 32 30.3 ± 0.9 0 ± 0 -133.3
1.1.10.05. Mitochondrial ABC transporter ABCB10, conformation 3 4ayx Mitochon. inner 2 12 30.0 ± 0.6 0 ± 0 -76.8
1.1.67.01. Transmembrane protein 14C 2los Mitochon. inner 1 3 26.8 ± 0.4 0 ± 2 -18.5
1.2.01.01. Receptor tyrosine kinase EphA1 2k1k Eukaryo. plasma 2 2 30.2 ± 1.5 0 ± 5 -43.3
1.1.10.05. Mitochondrial ABC transporter ABCB10, conformation 1 4ayt Mitochon. inner 2 12 30.4 ± 0.8 0 ± 0 -79.7
1.1.01.02. Beta-2 adrenergic receptor, inactive state, dimer 2rh1 Eukaryo. plasma 2 14 31.8 ± 0.9 0 ± 1 -143.2
1.1.61.01. Leukotriene C4 synthase 2uuh Endoplasm. reticulum 3 12 29.4 ± 1.1 0 ± 0 -55.2
1.1.12.01. Potassium channel subfamily K member 1 3ukm Eukaryo. plasma 2 12 31.8 ± 1.0 0 ± 0 -108.7
1.1.14.01. Aquaporin-1 1h6i Eukaryo. plasma 4 32 30.8 ± 1.1 0 ± 0 -135.6
1.2.25.01. Phospholamban 1zll Endoplasm. reticulum 5 5 30.5 ± 1.4 0 ± 2 -76.0
1.1.17.01. Rhesus Glycoprotein RhCG 3hd6 Eukaryo. plasma 3 36 31.8 ± 0.7 0 ± 0 -174.1
1.1.01.04. Smoothened homolog 4jkv Eukaryo. plasma 2 14 31.9 ± 1.2 0 ± 0 -98.5
1.1.14.01. Aquaporin-4 3gd8 Eukaryo. plasma 4 32 29.8 ± 1.1 0 ± 1 -122.9
1.1.61.01. FLAP protein (5-lipoxygenase activator) 2q7r Endoplasm. reticulum 3 12 30.3 ± 1.3 0 ± 1 -70.8
1.1.10.05. Mitochondrial ABC transporter ABCB10, conformation 2 4ayw Mitochon. inner 2 12 29.0 ± 0.8 0 ± 0 -65.8
1.1.61.01. Microsomal prostaglandin E synthase 1, different conformation 4al0 Eukaryo. plasma 3 12 28.8 ± 1.0 0 ± 1 -79.7
1.1.01.02. C-X-C chemokine receptor type 4, inactive, dimer, complex with antagonist 3odu Eukaryo. plasma 2 17 31.2 ± 1.1 0 ± 0 -129.5
1.1.01.02. Histamine H1 receptor 3rze Eukaryo. plasma 1 7 32.0 ± 1.4 1 ± 1 -72.4
1.1.01.02. Thrombin (proteinase-activated) receptor 1, PAR1 3vw7 Eukaryo. plasma 1 7 33.4 ± 1.9 1 ± 0 -72.2
1.1.01.02. Opioid kappa receptor 4djh Eukaryo. plasma 2 14 32.0 ± 0.8 1 ± 0 -146.6
1.1.10.05. Mitochondrial ABC transporter ABCB10, conformation 4 3zdq Mitochon. inner 2 12 30.8 ± 0.5 1 ± 0 -71.8
1.3.22.01. VDAC-1 channel, NMR model 2k4t Mitochon. outer 1 19 22.0 ± 1.5 1 ± 1 -34.8
1.2.44.01. Amyloid beta A4 protein, peptide 686-726, dimer 2loh Eukaryo. plasma 2 2 32.8 ± 1.6 1 ± 1 -34.1
1.1.69.01. HIG1 domain family member 1A 2lom Eukaryo. plasma 1 2 22.0 ± 5.0 1 ± 1 -27.3
1.1.61.01. Microsomal prostaglandin E synthase 1 3dww Endoplasm. reticulum 3 12 31.9 ± 1.1 2 ± 1 -97.3
2.2.26.01. Early endosome antigen 1 (EEA1), model of dimer with lipids 1joc Endosome 2 0 15.0 ± 0.4 2 ± 11 -34.0
1.2.25.01. Sarcolipin 1jdm Endoplasm. reticulum 1 1 29.6 ± 2.4 3 ± 7 -28.5
1.1.12.01. Potassium channel subfamily K member 4 3um7 Eukaryo. plasma 2 12 30.8 ± 1.2 3 ± 0 -93.2
1.2.01.01. Receptor tyrosine-protein kinase erbB-4, peptide 642-685 2l2t Eukaryo. plasma 2 2 32.4 ± 1.5 4 ± 2 -50.4
1.1.01.02. Muscarinic acetylcholine receptor M2 3uon Eukaryo. plasma 1 7 31.8 ± 2.1 4 ± 2 -68.5
1.2.21.01. BNip3 transmembrane domain homodimer 2ka2 Mitochon. outer 2 2 30.8 ± 1.8 4 ± 2 -29.2
1.1.15.01. Glycine receptor, alpha1 subunit 1vry Eukaryo. plasma 1 2 23.2 ± 3.7 5 ± 9 -25.3
1.2.10.01. Glycophorin A 1afo Eukaryo. plasma 2 2 31.9 ± 2.8 5 ± 6 -43.5
1.1.01.02. C-X-C chemokine receptor type 4, inactive, with cyclic peptide antagonist 3oe0 Eukaryo. plasma 2 14 32.2 ± 2.0 5 ± 6 -133.2
2.3.06.03. Gastric lipase, closed state 1hlg Secreted 1 0 3.2 ± 1.4 6 ± 12 -5.6
2.2.11.01. Synaptotagmin-17 2enp Eukaryo. plasma 1 0 4.6 ± 1.5 6 ± 14 -4.9
1.1.12.01. Potassium channel subfamily K member 4, different conformation 4i9w Eukaryo. plasma 2 8 30.8 ± 1.4 6 ± 0 -106.2
1.1.01.02. 5-hydroxytryptamine receptor 1B, conformation 2 4iaq Eukaryo. plasma 1 7 34.4 ± 1.7 6 ± 1 -77.4
2.2.11.01. Multiple C2 and transmembrane domain-containing protein 2 (MCTP2) 2ep6 Eukaryo. plasma 1 0 1.5 ± 1.5 7 ± 15 -3.0
1.1.01.02. Beta-2 adrenergic receptor, inactive state 4gbr Eukaryo. plasma 1 7 31.6 ± 1.3 7 ± 1 -71.7
1.2.02.01. Zeta-zeta dimer of T cell receptor 2hac Eukaryo. plasma 2 2 31.9 ± 2.3 7 ± 10 -43.2
1.1.01.02. Adenosine receptor A2a, complex with antibody 3vga Eukaryo. plasma 1 7 30.4 ± 1.4 7 ± 2 -62.8
1.1.01.02. 5-hydroxytryptamine receptor 1B, conformation 1 4iar Eukaryo. plasma 1 7 33.6 ± 1.8 7 ± 1 -76.4
1.1.01.02. Nociceptin receptor 4ea3 Eukaryo. plasma 1 7 32.0 ± 1.2 7 ± 1 -65.6
1.1.01.02. Adenosine receptor A2a, inactive state, complex with antagonist 3eml Eukaryo. plasma 1 7 31.8 ± 1.2 8 ± 12 -66.1
1.1.01.02. Beta-2 adrenergic receptor, active state, complex with G-protein 3sn6 Eukaryo. plasma 1 7 31.0 ± 1.6 8 ± 1 -68.2
1.1.01.02. Adenosine receptor A2a, complex with antagonist 3uza Eukaryo. plasma 1 7 31.6 ± 0.6 8 ± 1 -72.5
1.1.01.02. Dopamine D3 receptor 3pbl Eukaryo. plasma 1 7 33.0 ± 1.8 8 ± 1 -56.6
1.1.15.01. Nicotinic acetylcholine receptor, alpha4 subunit, in LDAO micelles 2lly Eukaryo. plasma 1 4 29.2 ± 1.2 8 ± 1 -49.2
1.1.01.02. C-X-C chemokine receptor type 4, inactive, complex with antagonist 3oe6 Eukaryo. plasma 1 7 35.3 ± 2.5 8 ± 7 -79.7
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4 3b7y Eukaryo. plasma 1 0 2.7 ± 1.5 9 ± 6 -4.1
1.1.01.02. Adenosine receptor A2a, inactive state, engineered, complex with inverse agonist 3pwh Eukaryo. plasma 1 7 31.0 ± 1.3 9 ± 0 -67.3
1.1.01.02. Beta-2 adrenergic receptor, active state, complex with antibody 3p0g Eukaryo. plasma 1 7 30.1 ± 1.4 9 ± 1 -62.9
1.1.01.02. Adenosine receptor A2a, partially active state, complex with agonist 3qak Eukaryo. plasma 1 7 29.8 ± 1.2 9 ± 0 -70.0
1.1.01.02. Adenosine receptor A2a, partially active state, engineered, complex with agonist 2ydv Eukaryo. plasma 1 7 31.0 ± 1.3 10 ± 0 -61.4
1.1.01.02. Sphingosine 1-phosphate receptor 1 3v2y Eukaryo. plasma 1 7 32.2 ± 1.4 10 ± 0 -65.9
1.2.25.02. Na,K-ATPase regulatory protein FXYD1 (phospholemman) 2jo1 Endoplasm. reticulum 1 1 30.6 ± 2.5 11 ± 4 -27.8
2.3.06.11. Monoglyceride lipase MGLL, open ligand-free conformation 3jw8 Eukaryo. plasma 1 0 8.1 ± 1.3 11 ± 9 -11.3
1.2.21.01. BNip3 transmembrane domain homodimer, second alternative structure 2j5d Mitochon. outer 2 2 30.8 ± 2.5 12 ± 0 -35.8
1.2.03.01. T-cell surface glycoprotein CD4 2klu Eukaryo. plasma 1 1 31.8 ± 2.6 12 ± 7 -23.7
1.2.01.01. Receptor tyrosine kinase EphA2 2k9y Eukaryo. plasma 2 2 31.8 ± 3.2 12 ± 14 -32.1
1.2.04.01. Integrin beta-3/alpha-V complex 3ije Eukaryo. plasma 2 0 6.1 ± 2.1 13 ± 14 -9.0
2.2.20.01. PH domain of docking protein 2 2d9w Eukaryo. plasma 1 0 2.2 ± 1.2 13 ± 17 -3.5
1.2.09.01. Stannin 1zza Mitochon. outer 1 1 30.0 ± 2.0 13 ± 2 -25.2
1.2.01.01. Receptor tyrosine kinase erbB-2, dimer 2jwa Eukaryo. plasma 2 2 31.9 ± 2.9 13 ± 9 -46.6
1.1.70.01. CAAX prenyl protease 1 homolog 4aw6 Endoplasm. reticulum 1 7 30.8 ± 1.3 13 ± 1 -75.9
1.2.04.01. Integrin alpha-IIb, complex with integrin beta-3 2knc Eukaryo. plasma 2 2 34.8 ± 1.4 13 ± 5 -46.2
2.2.14.01. C2 domain of coagulation factor V 1czs Eukaryo. plasma 1 0 3.4 ± 1.6 13 ± 15 -6.2
1.1.15.01. Nicotinic acetylcholine receptor, beta2 subunit, in LDAO micelles 2lm2 Eukaryo. plasma 1 4 29.2 ± 1.6 14 ± 2 -48.8
1.2.33.02. Monoamine oxidase B, dimer 2xfn Mitochon. outer 2 2 30.0 ± 3.2 14 ± 0 -14.5
1.2.08.01. TYRO protein tyrosine kinase-binding protein, homodimer 2l34 Eukaryo. plasma 2 2 31.8 ± 3.0 14 ± 10 -36.0
1.2.22.01. Activator of apoptosis harakiri, transmembrane helix 2l5b Mitochon. outer 1 1 29.8 ± 0.9 14 ± 11 -11.9
1.2.25.01. Phospholamban, monomer 2kb7 Endoplasm. reticulum 1 1 32.0 ± 2.2 15 ± 2 -34.6
1.2.01.01. Receptor tyrosine kinase erbB-2, complex with EGF receptor 2ks1 Eukaryo. plasma 2 2 32.0 ± 2.5 15 ± 5 -50.6
1.1.01.02. 5-hydroxytryptamine receptor 2B 4ib4 Eukaryo. plasma 1 7 34.0 ± 2.3 16 ± 2 -69.2
1.2.01.01. Receptor tyrosine-protein kinase erbB-3, peptide 640-670 2l9u Eukaryo. plasma 2 2 33.8 ± 2.4 16 ± 5 -44.6
1.1.15.01. Nicotinic acetylcholine receptor, beta2 subunit, in hexafluoroisopropanol/water 2ksr Eukaryo. plasma 1 4 29.1 ± 2.2 16 ± 1 -47.0
2.2.53.01. Fas apoptotic inhibitory molecule 1 3mx7 Eukaryo. plasma 1 0 4.2 ± 1.4 16 ± 13 -7.1
1.2.04.01. Integrin alpha-IIb, transmembrane helix 2k1a Eukaryo. plasma 1 1 34.4 ± 2.6 17 ± 6 -36.9
1.2.33.02. Monoamine oxidase A 2z5x Mitochon. outer 1 1 31.0 ± 2.1 17 ± 1 -21.4
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1uw5 Eukaryo. plasma 1 0 4.3 ± 1.5 18 ± 16 -5.4
1.1.01.02. Adenosine receptor A2a, inactive state, with annular lipids 4eiy Eukaryo. plasma 1 7 32.2 ± 1.2 18 ± 0 -70.4
1.2.04.01. Integrin beta-3, cytoplasmic domain 1s4x Eukaryo. plasma 1 0 6.9 ± 1.0 18 ± 10 -5.8
1.2.01.01. Platelet-derived growth factor receptor beta, 526-563 2l6w Eukaryo. plasma 2 2 34.8 ± 0.8 18 ± 1 -40.9
2.2.41.01. Beta-defensin 3 1kj6 Secreted 1 0 2.7 ± 1.3 18 ± 18 -5.1
1.1.69.01. HIG1 domain family member 1B 2lon Eukaryo. plasma 1 2 22.4 ± 1.2 19 ± 0 -13.7
1.1.01.02. C-X-C chemokine receptor type 1 2lnl Eukaryo. plasma 1 7 30.2 ± 0.9 19 ± 6 -54.4
1.1.01.02. Melanocortin-4 receptor model (inactive state) with antagonist AGRP 2iqv Eukaryo. plasma 1 7 31.9 ± 1.1 19 ± 0 -49.1
3.1.02.05. Acetylcholine receptor, subunit beta2, TMH 2 2k59 Eukaryo. plasma 1 1 30.2 ± 1.9 20 ± 4 -21.0
1.2.08.01. TYRO protein tyrosine kinase-binding protein, heterotrimer 2l35 Eukaryo. plasma 2 3 31.6 ± 3.2 20 ± 5 -40.3
1.2.04.01. Integrin alpha-IIb, complex with integrin beta-3 2k9j Eukaryo. plasma 2 2 36.4 ± 3.3 20 ± 1 -56.4
2.2.20.01. PH domain of 3-phosphoinositide-dependent protein kinase 1 1w1g Eukaryo. plasma 1 0 3.8 ± 1.8 20 ± 18 -4.8
2.2.14.02. SUN domain-containing protein 2 3unp Nuclear outer 3 0 2.7 ± 0.1 20 ± 0 -5.3
3.1.02.08. High affinity copper uptake protein 1, peptide 64-84 2ls2 Eukaryo. plasma 1 1 25.2 ± 4.2 21 ± 9 -19.0
3.1.02.01. Cannabinoid receptor 2, TMH 6 2ki9 Eukaryo. plasma 1 1 28.4 ± 2.2 21 ± 9 -17.0
1.1.68.01. Transmembrane protein 141 2lor Undefined 1 2 24.4 ± 4.0 21 ± 0 -22.2
1.2.34.01. Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4) 2lat Endoplasm. reticulum 1 1 31.8 ± 3.5 23 ± 16 -21.3
1.1.67.01. Transmembrane proteins 14A 2lop Mitochon. inner 1 3 28.8 ± 2.0 23 ± 1 -35.5
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase SMURF1 3pyc Eukaryo. plasma 1 0 4.5 ± 2.1 23 ± 17 -5.7
2.2.11.01. E3 ubiquitin-protein ligase SMURF2 2jqz Eukaryo. plasma 1 0 4.2 ± 1.8 23 ± 17 -5.6
1.1.56.01. Steryl-sulfatase 1p49 Endoplasm. reticulum 1 2 29.6 ± 1.1 23 ± 0 -34.6
2.2.26.01. Early endosome antigen 1 (EEA1), monomer 1hyi Endosome 1 0 3.0 ± 2.0 24 ± 17 -3.5
1.1.01.02. Melanocortin-4 receptor model (active state) with agonist NDP-MSH 2iqr Eukaryo. plasma 1 7 33.5 ± 2.0 24 ± 0 -60.6
1.2.21.01. BNip3 transmembrane domain homodimer, first alternative structure 2ka1 Mitochon. outer 2 2 31.8 ± 2.3 24 ± 8 -34.9
2.1.20.01. Coagulation factor VIIa 1dan Eukaryo. plasma 4 0 4.2 ± 6.0 25 ± 26 -4.9
2.2.11.01. E3 ubiquitin-protein ligase Itchy homolog 2nq3 Eukaryo. plasma 1 0 3.4 ± 1.9 25 ± 17 -6.7
2.4.42.01. Cholesteryl ester transfer protein 2obd Secreted 1 0 7.4 ± 2.9 26 ± 6 -7.0
1.2.22.01. Bcl-2-like protein 1, complex with alpha-beta-foldamer 4a1u Mitochon. outer 1 0 5.8 ± 0.3 26 ± 5 -5.7
2.2.11.01. Synaptotagmin-7 2d8k Vesicle 1 0 2.8 ± 1.3 27 ± 16 -6.6
1.2.41.01. Acyl-CoA-binding domain-containing protein 5 3flv Peroxisome 1 0 4.6 ± 2.8 28 ± 3 -4.9
2.2.14.01. C2 domain of coagulation factor VIII 1d7p Eukaryo. plasma 1 0 4.8 ± 2.0 28 ± 10 -8.8
2.2.20.01. Son of sevenless homolog 1 (two domains) 1dbh Eukaryo. plasma 1 0 2.7 ± 2.8 28 ± 19 -4.2
2.2.11.01. Synaptotagmin-1, C2A domain (Calcium free) 3f00 Eukaryo. plasma 1 0 1.4 ± 1.5 29 ± 18 -3.3
1.2.32.01. Cytochrome P450 2D6, conformation 1 2f9q Endoplasm. reticulum 1 0 7.0 ± 1.8 29 ± 10 -12.0
2.2.27.01. RAF-1 proto-oncogene serine/threonine-protein kinase 1faq Eukaryo. plasma 1 0 4.8 ± 1.1 30 ± 14 -7.3
1.2.44.01. Amyloid beta A4 protein, peptide 686-726 2llm Eukaryo. plasma 1 1 32.8 ± 2.2 30 ± 0 -30.8
2.3.06.01. Acetylcholinesterase 4ey4 Eukaryo. plasma 1 0 3.2 ± 0.5 33 ± 2 -8.4
2.2.29.01. Multivesicular body subunit 12B 3tow Endosome 1 0 4.5 ± 2.3 33 ± 22 -5.8
1.2.22.01. Apoptosis regulator Bcl-2 1g5m Mitochon. outer 1 0 4.2 ± 1.4 33 ± 11 -6.6
2.2.11.01. Synaptotagmin-4 1ugk Eukaryo. plasma 1 0 2.5 ± 1.7 34 ± 11 -3.5
2.3.14.01. Neurofibromin 2d4q Eukaryo. plasma 1 0 1.6 ± 2.0 34 ± 19 -3.3
2.2.27.01. Diacylglycerol kinase delta 1r79 Eukaryo. plasma 1 0 3.3 ± 1.6 34 ± 19 -4.9
1.2.32.01. Cytochrome P450 2D6, conformation 2 3tda Endoplasm. reticulum 1 0 8.0 ± 0.7 35 ± 7 -12.5
1.2.32.01. Cytochrome P450 2D6, conformation 3 3qm4 Endoplasm. reticulum 1 0 9.0 ± 1.4 35 ± 11 -9.3
2.4.52.01. Spondin-2 3d34 Secreted 1 0 6.3 ± 0.7 35 ± 5 -10.4
3.1.02.01. Apelin receptor, peptide 1-55 2low Eukaryo. plasma 1 1 26.4 ± 5.1 35 ± 2 -16.7
2.4.33.01. 72 kDa type IV collagenase 1eak Eukaryo. plasma 1 0 4.1 ± 1.6 37 ± 6 -6.6
1.2.01.01. Insulin-like growth factor 1 receptor 1p4o Eukaryo. plasma 1 0 2.4 ± 1.0 37 ± 11 -5.1
2.2.34.08. Agouti-related protein 1mr0 Secreted 1 0 3.1 ± 2.0 37 ± 18 -5.6
2.3.05.06. Endothelin-converting enzyme 2 2pxx Golgi 1 0 7.1 ± 1.3 37 ± 8 -8.4
1.2.33.02. Monoamine oxidase B, monomer 1s3e Mitochon. outer 2 0 7.3 ± 0.6 37 ± 1 -14.2
2.2.06.02. Fatty acid-binding protein 9 4a60 Eukaryo. plasma 1 0 3.2 ± 1.1 38 ± 6 -4.6
2.3.02.01. Phospholipase C-beta isoform 2 2zkm Eukaryo. plasma 1 0 2.2 ± 2.9 38 ± 12 -3.6
2.2.26.01. FYVE domain of protein 27 1x4u Vesicle 1 0 4.3 ± 1.9 38 ± 19 -6.9
1.2.44.01. Amyloid beta A4 protein (peptide 671-770) 2lp1 Eukaryo. plasma 1 1 23.6 ± 5.6 38 ± 5 -21.2
3.1.02.05. Acetylcholine receptor, subunit beta2, TMH 1 2k58 Eukaryo. plasma 1 1 30.6 ± 6.0 39 ± 7 -22.0
2.2.14.01. Coagulation factor VIII 2r7e Eukaryo. plasma 2 0 4.5 ± 3.0 39 ± 6 -11.5
2.3.02.01. Phospholipase C-beta isoform 3, complex with G-protein subunit alpha Q 3ohm Eukaryo. plasma 2 0 7.5 ± 2.0 39 ± 5 -6.9
1.2.04.01. Integrin alpha-1 2l8s Eukaryo. plasma 1 1 32.0 ± 3.7 40 ± 1 -34.5
2.3.13.07. Chloride intracellular channel protein 1 1rk4 Nuclear outer 1 0 3.0 ± 1.0 40 ± 5 -5.5
2.4.06.01. STAR-related lipid transfer protein 11, complex with C18 ceramide 2e3q Golgi 1 0 4.3 ± 2.0 41 ± 17 -3.7
2.2.06.02. Cellular retinoic acid-binding protein 2 1cbs Nuclear outer 1 0 7.1 ± 1.9 41 ± 13 -5.9
2.1.29.04. Apolipoprotein C-II 1i5j Secreted 1 0 4.4 ± 2.3 42 ± 3 -9.9
2.2.06.01. Complement component C8 gamma chain 1lf7 Secreted 1 0 1.9 ± 2.2 43 ± 12 -2.6
3.1.02.08. High affinity copper uptake protein 1, peptide 132-157 2ls3 Eukaryo. plasma 1 1 20.8 ± 3.4 43 ± 1 -20.8
2.3.06.01. Butyryl cholinesterase 1p0i Eukaryo. plasma 1 0 3.1 ± 0.8 43 ± 10 -6.4
2.4.06.01. STAR-related lipid transfer protein 11, apoprotein (open state) 2e3m Golgi 1 0 3.4 ± 1.1 44 ± 12 -6.1
1.2.32.01. Cytochrome P450 2A6 1z10 Endoplasm. reticulum 1 0 5.0 ± 1.7 44 ± 18 -9.5
2.2.06.02. Retinoid-binding protein 7 1lpj Eukaryo. plasma 1 0 2.6 ± 1.1 44 ± 13 -6.0
1.2.04.01. Integrin beta-3, cytoplasmic domain, monophosphorylated (747pY) 2ljd Eukaryo. plasma 1 0 8.1 ± 0.6 44 ± 4 -7.6
3.1.31.01. Dermcidin 2ksg Secreted 1 0 4.7 ± 1.4 45 ± 6 -7.0
2.3.06.08. Pancreatic lipase, complex with colipase from Pig 1n8s Secreted 2 0 7.6 ± 0.6 45 ± 4 -10.8
1.2.01.01. Receptor tyrosine-protein kinase erbB-3, extracellular domains 1m6b Eukaryo. plasma 1 0 2.0 ± 1.6 45 ± 5 -3.9
2.2.06.01. Neutrophil gelatinase-associated lipocalin 3fw5 Secreted 1 0 2.0 ± 1.2 45 ± 9 -3.1
3.1.14.01. Neuropeptide K 2b19 Secreted 1 0 5.1 ± 4.3 46 ± 8 -5.7
1.2.03.02. T-cell-specific surface glycoprotein CD28 1yjd Eukaryo. plasma 1 0 4.5 ± 0.6 46 ± 11 -3.6
2.2.56.01. Beta-2-glycoprotein 1 3op8 Secreted 1 0 4.2 ± 1.8 47 ± 10 -6.1
1.2.32.01. Cytochrome P450 2A13 2p85 Endoplasm. reticulum 1 0 4.9 ± 0.4 47 ± 2 -10.0
2.2.06.02. Myelin P2 protein 2wut Eukaryo. plasma 1 0 4.1 ± 0.5 47 ± 7 -3.4
2.4.06.01. StAR-related lipid transfer protein 5 2r55 Eukaryo. plasma 1 0 1.7 ± 1.2 47 ± 19 -4.8
2.2.26.01. RUN and FYVE domain-containing protein 1 2yw8 Endosome 1 0 0.7 ± 3.4 48 ± 38 -2.8
2.2.21.02. Fibroblast growth factor 19 1pwa Secreted 1 0 2.9 ± 1.5 48 ± 21 -4.7
1.2.32.01. Cytochrome P450 2R1 3czh Endoplasm. reticulum 1 0 8.3 ± 1.5 48 ± 13 -13.2
2.3.16.07. Ras-related protein Rab-9A 1wms Eukaryo. plasma 1 0 1.9 ± 0.8 48 ± 7 -5.0
1.2.32.01. Cytochrome P450 11B2, mitochondrial 4dvq Mitochon. inner 1 0 4.8 ± 0.6 48 ± 4 -9.1
1.2.32.01. Cytochrome P450 2E1 3e6i Endoplasm. reticulum 1 0 8.3 ± 2.0 49 ± 8 -14.2
2.2.06.02. Muscle fatty acid binding protein 1hmt Eukaryo. plasma 1 0 4.3 ± 1.6 49 ± 12 -5.0
1.2.04.01. Integrin beta-3, transmembrane helix 2rmz Eukaryo. plasma 1 1 30.0 ± 3.6 49 ± 2 -36.0
1.2.32.01. Cholesterol side-chain cleavage enzyme (P450 11A1), complex with adrenodoxin 3n9y Mitochon. inner 1 0 4.1 ± 0.6 49 ± 5 -6.2
2.2.12.03. Ganglioside GM2 activator, different conformation 1pub Lysosome 1 0 4.9 ± 0.7 50 ± 8 -7.3
2.3.06.13. Protein Ndr1 2xmr Eukaryo. plasma 1 0 8.2 ± 2.6 50 ± 10 -8.8
3.1.11.03. Motilin 1lbj Secreted 1 0 8.6 ± 1.6 51 ± 18 -4.9
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 2 3mdm Endoplasm. reticulum 1 0 3.8 ± 1.3 51 ± 8 -5.9
2.2.06.02. Adipocyte lipid-binding protein 1tow Eukaryo. plasma 1 0 2.5 ± 1.7 51 ± 18 -4.5
3.3.02.01. Collagen 2wuh Secreted 4 0 3.6 ± 1.6 51 ± 9 -9.5
1.2.37.01. ADP-ribosyl cyclase 1 3f6y Eukaryo. plasma 1 0 2.5 ± 2.4 51 ± 9 -6.3
2.2.06.02. Brain fatty acid binding protein 1fdq Eukaryo. plasma 1 0 3.1 ± 1.4 51 ± 15 -4.9
2.1.02.01. 12S-Lipoxygenase 3d3l Eukaryo. plasma 1 0 5.0 ± 0.6 51 ± 3 -9.0
2.2.11.01. Protein kinase C delta 1yrk Eukaryo. plasma 1 0 2.0 ± 1.6 52 ± 19 -1.8
2.2.30.01. Elafin, complex with elastase from Pig 1fle Secreted 2 0 4.4 ± 2.0 52 ± 11 -6.3
2.1.01.01. Phospholipase A2, group IB 3elo Secreted 1 0 0.4 ± 1.5 52 ± 16 -3.5
1.2.32.01. Cytochrome P450 3A4, conformation 2 3nxu Endoplasm. reticulum 1 0 9.3 ± 1.0 52 ± 12 -17.5
2.1.56.01. PALS1-associated tight junction protein 1vf6 Eukaryo. plasma 2 0 5.8 ± 0.4 53 ± 2 -9.4
2.4.06.01. Phosphatidylcholine transfer protein 1ln1 Eukaryo. plasma 1 0 3.8 ± 1.8 53 ± 16 -4.8
2.2.20.01. RAC-gamma serine/threonine-protein kinase 2x18 Eukaryo. plasma 1 0 1.5 ± 1.1 53 ± 4 -3.8
2.2.12.02. Rho GDP-dissociation inhibitor 1 1qvy Eukaryo. plasma 1 0 2.8 ± 1.7 53 ± 19 -5.1
2.2.06.02. Cellular retinol-binding protein III 1ggl Eukaryo. plasma 1 0 3.3 ± 1.9 53 ± 16 -4.9
2.1.20.01. Coagulation factor XIV (protein C) in complex with its receptor 1lqv Eukaryo. plasma 2 0 3.4 ± 3.9 53 ± 14 -5.6
2.4.38.01. Peptidoglycan recognition protein 3 1sk4 Secreted 1 0 6.1 ± 1.5 54 ± 7 -8.5
2.4.48.01. PPPDE peptidase domain-containing protein 2 3ebq Undefined 1 0 8.3 ± 2.6 54 ± 6 -7.6
1.2.01.01. Macrophage colony-stimulating factor 1 receptor 3bea Eukaryo. plasma 1 0 2.9 ± 1.5 54 ± 19 -4.2
3.1.02.02. Voltage sensor of calcium-activated potassium channel 2k44 Eukaryo. plasma 1 0 7.5 ± 3.0 54 ± 4 -9.8
2.1.14.01. Peroxisomal targeting signal 1 receptor 1fch Peroxisome 1 0 6.9 ± 1.2 54 ± 3 -6.7
1.2.30.01. Potassium voltage-gated channel subfamily E member 1 2k21 Eukaryo. plasma 1 1 12.1 ± 0.4 54 ± 2 -24.7
2.3.06.11. Monoglyceride lipase MGLL, closed ligand-bound conformation 3pe6 Eukaryo. plasma 1 0 0.9 ± 3.0 54 ± 28 -2.7
1.2.32.01. Cytochrome P450 2B6, different conformation 3ua5 Endoplasm. reticulum 1 0 4.7 ± 1.1 55 ± 3 -12.9
2.4.07.01. PX domain of NADH oxidase (p40phox), ligand-bound 1h6h Endosome 1 0 3.9 ± 2.0 55 ± 14 -6.0
2.2.06.02. Retinol-binding protein 2 2rcq Eukaryo. plasma 1 0 2.9 ± 1.7 55 ± 6 -5.5
2.3.03.01. Dihydroorotate dehydrogenase 1d3h Mitochon. inner 1 0 3.4 ± 0.8 55 ± 6 -10.1
2.3.06.04. Palmitoyl-protein thioesterase 1 3gro Lysosome 1 0 3.6 ± 0.1 55 ± 3 -6.8
2.2.20.01. Oxysterol binding protein-related protein 11 2d9x Eukaryo. plasma 1 0 1.4 ± 1.7 55 ± 18 -3.1
2.3.14.01. Retinaldehyde-binding protein 1, closed state, more complete structure 3hy5 Eukaryo. plasma 1 0 2.0 ± 3.9 55 ± 17 -4.5
2.4.07.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Golgi 1 0 2.5 ± 1.3 56 ± 16 -4.8
2.2.06.02. Epidermal fatty acid binding protein 1b56 Eukaryo. plasma 1 0 2.5 ± 2.0 56 ± 18 -3.5
1.2.32.01. Steroid 17-alpha-hydroxylase/17,20 lyase (P450 17A1) 3swz Endoplasm. reticulum 1 0 4.2 ± 1.6 56 ± 3 -8.4
2.4.12.01. Liver-expressed antimicrobial peptide 2 2l1q Secreted 1 0 5.3 ± 1.4 56 ± 11 -2.7
1.2.32.01. Cytochrome P450 2B6 3ibd Endoplasm. reticulum 1 0 4.7 ± 1.0 57 ± 3 -10.8
2.4.06.01. Acyl-coenzyme A thioesterase 11 3fo5 Endoplasm. reticulum 1 0 2.3 ± 1.4 57 ± 7 -3.9
2.2.12.03. Ganglioside GM2 activator 1tjj Lysosome 1 0 4.2 ± 0.3 57 ± 4 -8.3
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3ld6 Endoplasm. reticulum 1 0 8.9 ± 0.6 57 ± 2 -16.8
2.2.11.01. Cytosolic phospholipase A2, group IVA 1rlw Eukaryo. plasma 1 0 6.4 ± 1.9 57 ± 17 -7.8
2.3.16.07. Ras-related C3 botulinum toxin substrate 1 2p2l Eukaryo. plasma 1 0 3.2 ± 0.8 58 ± 2 -5.2
2.4.07.01. Sorting nexin-11, conformation 2 4ikd Eukaryo. plasma 1 0 3.0 ± 1.2 58 ± 4 -5.3
2.1.24.01. Saposin B (peptide 195-273) 1n69 Lysosome 2 0 1.2 ± 1.0 58 ± 6 -2.4
1.2.32.01. Cytochrome P450 19A1 (aromatase, estrogen synthetase) 3eqm Endoplasm. reticulum 1 0 6.1 ± 1.2 58 ± 8 -12.4
2.3.16.06. ADP-ribosylation factor-like protein 8A 2h18 Endosome 1 0 1.2 ± 3.6 58 ± 28 -2.6
2.2.12.03. Ganglioside GM2 activator, apo-protein 2ag4 Lysosome 1 0 3.1 ± 1.3 58 ± 12 -5.4
1.2.33.02. Protoporphyrinogen oxidase 3nks Mitochon. inner 1 0 4.8 ± 1.0 59 ± 3 -9.6
2.2.20.01. Triple functional domain protein 1nty Eukaryo. plasma 1 0 3.2 ± 2.0 59 ± 16 -3.9
1.2.03.07. Cell adhesion molecule complex 3n1f Eukaryo. plasma 2 0 5.2 ± 0.9 59 ± 4 -5.7
2.2.20.01. Dual adaptor of phosphotyrosine and 3-phosphoinositides 1fao Eukaryo. plasma 1 0 2.4 ± 2.0 59 ± 19 -3.9
1.2.39.01. Endoplasmic reticulum aminopeptidase 1, different conformation 2yd0 Endoplasm. reticulum 1 0 4.1 ± 2.2 59 ± 8 -4.6
1.2.32.01. Cytochrome P450 2C9, different conformation 1r9o Endoplasm. reticulum 1 0 4.0 ± 1.1 59 ± 8 -10.1
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-bound 1o7k Endosome 1 0 15.2 ± 1.7 60 ± 15 -18.4
2.3.06.04. Palmitoyl protein thioesterase 2 1pja Lysosome 1 0 3.7 ± 1.6 60 ± 15 -4.6
1.2.39.01. Endoplasmic reticulum aminopeptidase 2 3se6 Endoplasm. reticulum 1 0 2.5 ± 1.8 60 ± 21 -4.5
2.3.06.01. Acetylcholinesterase, complex with fasciculin-2 1f8u Eukaryo. plasma 2 0 2.6 ± 1.0 60 ± 9 -7.3
2.2.20.01. Pleckstrin 1pls Eukaryo. plasma 1 0 3.6 ± 2.0 61 ± 19 -3.8
2.4.07.01. Sorting nexin-11, conformation 1 4ikb Eukaryo. plasma 1 0 5.2 ± 2.7 61 ± 8 -6.1
2.2.03.01. Beta-secretase 1 2wf1 Eukaryo. plasma 1 0 1.7 ± 1.2 61 ± 6 -4.9
2.2.06.02. Intestinal fatty acid binding protein 1kzw Eukaryo. plasma 1 0 2.9 ± 1.3 61 ± 12 -4.1
2.1.49.01. cGMP-specific 3',5'-cyclic phosphodiesterase 1rkp Eukaryo. plasma 1 0 5.0 ± 1.6 61 ± 11 -5.2
2.2.20.01. Phosphoinositol 3-phosphate binding protein 1 1upr Eukaryo. plasma 1 0 3.0 ± 1.4 62 ± 19 -3.6
2.1.59.01. Squalene synthase, conformation 2 3vjc Endoplasm. reticulum 1 0 7.3 ± 0.9 62 ± 4 -6.9
1.2.04.01. Integrin beta-3, cytoplasmic domain, monophosphorylated (747pY) 2ljf Eukaryo. plasma 1 0 0.6 ± 1.6 62 ± 14 -1.8
2.3.14.01. SEC14-like protein 2 (supernatant factor protein) 1o6u Eukaryo. plasma 1 0 3.6 ± 1.4 62 ± 14 -4.9
2.2.34.08. Agouti-signaling protein 1y7j Secreted 1 0 3.8 ± 1.6 62 ± 7 -6.9
2.4.20.04. Group XVI phospholipase A1/A2 2kyt Eukaryo. plasma 1 0 4.1 ± 1.5 62 ± 18 -4.9
2.4.04.01. Type II inositol-1,4,5-trisphosphate 5-phosphatase 3n9v Eukaryo. plasma 1 0 4.1 ± 1.4 63 ± 6 -6.0
2.1.29.01. Apolipoprotein A-I 2a01 Secreted 1 0 4.8 ± 1.2 63 ± 11 -6.5
1.2.39.01. Endoplasmic reticulum aminopeptidase 1 3mdj Endoplasm. reticulum 1 0 1.9 ± 3.6 63 ± 10 -4.6
2.2.17.01. Follicle-stimulating hormone-receptor complex 1xwd Eukaryo. plasma 3 0 3.1 ± 1.5 63 ± 7 -7.2
3.1.11.02. Gastric inhibitory polypeptide, complex with N-terminal domain of GPCR 2qkh Secreted 2 0 6.3 ± 3.2 64 ± 23 -5.9
2.3.14.01. Alpha-tocopherol transfer protein, open state 1oiz Golgi 1 0 8.1 ± 1.0 64 ± 10 -17.6
1.2.32.01. Cytochrome P450 1A1 4i8v Endoplasm. reticulum 1 0 7.1 ± 1.0 64 ± 3 -15.1
2.2.20.01. Pleckstrin homology domain-containing family A member 5 (PLEKHA5) 2dkp Eukaryo. plasma 1 0 3.0 ± 0.9 64 ± 6 -3.9
2.2.20.01. Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 2da0 Eukaryo. plasma 1 0 1.7 ± 2.5 64 ± 20 -2.5
1.2.32.01. Prostacyclin synthase (cytochrome P450 8A1) 3b6h Endoplasm. reticulum 1 0 5.0 ± 1.6 64 ± 18 -6.3
2.3.06.05. Acyl-protein thioesterase 1 1fj2 Eukaryo. plasma 1 0 9.6 ± 2.0 64 ± 14 -4.7
2.2.27.01. Beta-chimaerin 1xa6 Eukaryo. plasma 1 0 2.1 ± 1.7 65 ± 7 -5.1
2.1.29.02. Apolipoprotein A-II, different conformation 1l6l Secreted 2 0 3.9 ± 1.2 65 ± 8 -10.6
2.4.31.01. Ficolin-1 2wnp Eukaryo. plasma 1 0 3.0 ± 0.8 65 ± 2 -5.3
1.2.32.01. Cytochrome P450 2C8 1pq2 Endoplasm. reticulum 1 0 3.8 ± 1.8 65 ± 9 -8.6
1.2.32.01. Cytochrome P450 1A2 2hi4 Endoplasm. reticulum 1 0 6.9 ± 1.0 66 ± 9 -16.2
2.3.16.06. ADP-ribosylation factor-like protein 5A 1z6y Eukaryo. plasma 1 0 1.5 ± 1.9 66 ± 15 -4.0
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 405-424 1btq Eukaryo. plasma 1 0 13.6 ± 2.1 67 ± 11 -22.5
1.2.32.01. Cytochrome P450 3A4, conformation 1 1tqn Endoplasm. reticulum 1 0 8.7 ± 1.0 67 ± 11 -18.5
2.2.20.01. Pleckstrin homology domain-containing family A member 6 (PLEKHA6) 2d9y Eukaryo. plasma 1 0 1.0 ± 0.3 67 ± 1 -6.2
2.2.20.01. Rac-alpha serine/threonine kinase 1unq Eukaryo. plasma 1 0 2.7 ± 2.0 67 ± 18 -3.9
3.4.08.01. Neurotensin 2oyv Secreted 1 0 7.3 ± 2.6 67 ± 17 -5.3
2.3.18.01. Carnitine O-octanoyltransferase 1nm8 Mitochon. inner 1 0 1.7 ± 3.0 67 ± 15 -5.3
2.2.02.01. Mitochondrial serine protease HtrA2 1lcy Mitochon. inner 1 0 7.4 ± 1.8 67 ± 14 -5.1
2.2.20.01. PH domain of Src-associated adaptor 55 protein 1u5d Eukaryo. plasma 2 0 4.0 ± 1.8 68 ± 18 -6.4
1.2.03.05. Prolactin receptor 3nce Eukaryo. plasma 2 0 3.4 ± 1.5 68 ± 2 -5.7
2.2.12.01. Lymphocyte antigen 96 2e56 Secreted 1 0 3.6 ± 0.7 68 ± 4 -6.7
2.2.06.01. Apolipoprotein D 2hzq Secreted 1 0 4.5 ± 0.9 69 ± 5 -7.8
2.4.07.01. PX domain of sorting nexin-17 (SNX17) 3fog Endosome 1 0 3.4 ± 1.0 69 ± 12 -4.9
2.2.12.01. Lymphocyte antigen 96, complex with Toll-like receptor 4 2z65 Secreted 2 0 3.2 ± 2.0 69 ± 2 -5.7
1.2.04.01. Integrin alpha-IIb, cytoplasmic domain 1s4w Eukaryo. plasma 1 0 2.9 ± 0.3 69 ± 3 -9.1
1.2.32.01. Cholesterol 7-alpha-monooxygenase (P450 7A1) 3dax Endoplasm. reticulum 1 0 1.8 ± 1.9 69 ± 8 -3.9
2.2.20.01. PH domain of pleckstrin homology domain-containing family A member 3 3rcp Eukaryo. plasma 1 0 2.8 ± 1.5 70 ± 9 -4.8
2.1.24.01. Saposin A (peptide 60-140) 2dob Lysosome 1 0 2.0 ± 2.5 70 ± 29 -4.2
2.2.06.01. Retinol binding protein 1rbp Secreted 1 0 3.5 ± 0.8 70 ± 6 -5.8
3.1.11.02. Glucagon-like peptide 1, in complex with extracellular domain of its GPCR 3iol Secreted 2 0 2.8 ± 04.0 70 ± 1 -6.7
2.3.08.01. Cytosolic phospholipase A2, group IVA 1cjy Nuclear outer 1 0 5.8 ± 1.0 70 ± 9 -9.9
2.4.03.01. Tubby protein homolog 1s31 Eukaryo. plasma 1 0 6.8 ± 1.0 71 ± 2 -7.6
2.2.12.04. ADP-ribosylation factor binding protein Gga3 domain 1p4u Golgi 1 0 6.5 ± 1.1 71 ± 11 -6.5
3.1.12.01. Endothelin-1 1edn Secreted 1 0 4.3 ± 1.2 71 ± 25 -5.4
2.2.11.01. Synaptotagmin-like protein 4 3fdw Vesicle 1 0 3.0 ± 2.0 71 ± 17 -3.6
2.2.20.01. Fermitin family homolog 2 4f7h Eukaryo. plasma 1 0 2.2 ± 1.4 72 ± 4 -4.2
2.2.20.01. Rho GTPase-activating protein 27 3pp2 Eukaryo. plasma 1 0 2.5 ± 2.2 72 ± 14 -3.4
1.2.03.03. Myelin protein P0 3oai Eukaryo. plasma 1 0 2.2 ± 1.2 72 ± 6 -5.8
2.4.07.01. Sorting nexin-23 (Kinesin-like protein KIF16B) 2v14 Endosome 1 0 3.3 ± 3.0 72 ± 14 -5.4
2.1.29.03. Apolipoprotein C-I, peptide 33-50 1ale Secreted 1 0 4.9 ± 1.0 72 ± 4 -7.8
2.4.07.01. NADPH oxidase organizer 1, PX domain 2l73 Eukaryo. plasma 1 0 2.8 ± 1.9 72 ± 13 -5.1
2.2.20.01. Proto-oncogene vav, complex with Ras-related C3 botulinum toxin substrate 1 3bji Eukaryo. plasma 2 0 2.5 ± 2.2 72 ± 14 -3.4
3.1.11.04. Orexin-A 1wso Secreted 1 0 6.4 ± 1.7 72 ± 14 -5.5
1.2.40.01. Mitochondria fission protein Fis1 1nzn Mitochon. outer 1 0 6.1 ± 1.4 72 ± 8 -9.3
3.1.13.01. Calcitonin 2jxz Secreted 1 0 5.5 ± 1.1 72 ± 6 -11.5
1.2.32.01. Cholesterol 7-alpha-monooxygenase (P450 7A1), different conformation 3sn5 Endoplasm. reticulum 1 0 6.0 ± 1.9 73 ± 4 -6.5
2.1.29.01. Apolipoprotein E 2l7b Secreted 1 0 2.5 ± 1.0 73 ± 8 -4.9
2.4.33.01. 72 kDa type IV collagenase 1ck7 Eukaryo. plasma 1 0 2.9 ± 1.7 73 ± 9 -4.0
2.1.15.02. ADP-ribosylation factor-binding protein GGA2 1mhq Golgi 1 0 4.2 ± 1.2 74 ± 5 -4.1
2.2.41.01. Beta-defensin 1 1ijv Secreted 1 0 3.5 ± 1.9 74 ± 17 -5.4
2.2.17.01. Follicle-stimulating hormone, complex of alpha and beta chains 1fl7 Eukaryo. plasma 4 0 2.0 ± 1.6 74 ± 9 -5.3
3.1.11.01. Neuropeptide Y 1ron Secreted 1 0 7.9 ± 1.6 74 ± 10 -8.6
1.2.41.01. Acyl-CoA-binding protein 2cb8 Peroxisome 1 0 2.7 ± 2.0 74 ± 29 -5.2
1.2.04.01. Integrin beta-3, cytoplasmic domain, biphosphorylated (747pY, 759pY) 2lje Eukaryo. plasma 1 0 4.0 ± 0.5 74 ± 2 -7.0
3.1.02.07. Sodium/hydrogen exchanger 1, TMH XI 2kbv Eukaryo. plasma 1 0 2.7 ± 6.9 74 ± 4 -4.9
2.1.41.01. Phosphatidylinositol 3-kinase catalytic subunit type 3 3ls8 Eukaryo. plasma 1 0 2.7 ± 2.2 75 ± 9 -4.7
2.2.27.01. C1 domanin of SH3 and cysteine-rich domain-containing protein 3 2db6 Eukaryo. plasma 1 0 2.7 ± 0.1 75 ± 0 -4.8
3.1.02.01. Second intracellular loop (118-149) of alpha-2A adrenergic receptor 1hod Eukaryo. plasma 1 0 3.9 ± 4.1 75 ± 3 -7.2
2.4.05.01. Sterol carrier protein 2 like domain of multifunctional enzyme type 2 1ikt Peroxisome 1 0 3.5 ± 1.2 75 ± 17 -4.0
2.2.12.04. ADP-ribosylation factor-binding protein GGA1 1om9 Golgi 2 0 6.1 ± 1.0 76 ± 21 -5.1
2.2.41.01. Alpha-defensin 6 1zmq Secreted 1 0 3.7 ± 1.6 76 ± 18 -3.6
2.2.41.01. Alpha-defensin 4 1zmm Secreted 1 0 2.2 ± 1.0 76 ± 10 -5.5
2.2.11.01. Extended synaptotagmin-2 2dmg Eukaryo. plasma 1 0 2.4 ± 1.0 76 ± 5 -4.8
2.4.06.01. Steroidogenic acute regulatory protein, mitochondrial 3p0l Mitochon. outer 1 0 3.0 ± 1.3 76 ± 10 -4.7
2.3.16.07. GTP-binding protein Rheb 1xtq Eukaryo. plasma 1 0 2.6 ± 0.6 76 ± 20 -5.1
2.3.14.01. Alpha-tocopherol transfer protein, closed state with ligand 1r5l Golgi 1 0 4.3 ± 1.0 77 ± 9 -11.8
1.2.41.01. Acyl-CoA-binding domain-containing protein 4 2wh5 Peroxisome 1 0 7.2 ± 2.4 77 ± 26 -5.7
2.3.14.01. Retinaldehyde-binding protein 1, closed state 3hx3 Eukaryo. plasma 1 0 1.2 ± 2.9 77 ± 32 -4.8
2.4.33.01. 72 kDa type IV collagenase complex 1gxd Eukaryo. plasma 2 0 2.5 ± 1.1 77 ± 4 -5.4
2.4.07.01. PX domain of serine/threonine-protein kinase Sgk3 1xte Endosome 1 0 1.2 ± 1.4 77 ± 11 -2.9
2.3.19.02. Histo-blood group ABO system transferase 2rj6 Golgi 1 0 2.1 ± 1.3 77 ± 3 -7.1
2.4.06.01. StAR-related lipid transfer protein 13 2pso Eukaryo. plasma 1 0 3.1 ± 4.0 77 ± 27 -4.6
2.1.05.01. Lanosterol synthase 1w6k Endoplasm. reticulum 1 0 7.6 ± 1.0 77 ± 4 -17.8
2.1.24.01. Pulmonary surfactant-associated protein B fragments 2dwf Secreted 1 0 5.6 ± 1.3 77 ± 4 -9.5
2.1.18.01. Annexin III 1axn Eukaryo. plasma 1 0 2.7 ± 0.8 77 ± 11 -5.7
2.2.20.01. Oxysterol-binding protein-related protein 8 1v88 Eukaryo. plasma 1 0 1.7 ± 1.2 78 ± 4 -4.6
2.2.06.02. Prostaglandin-H2 D-isomerase 3o22 Endoplasm. reticulum 1 0 0.7 ± 1.2 78 ± 13 -2.4
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform 3hhm Eukaryo. plasma 2 0 1.3 ± 0.5 78 ± 1 -5.5
3.1.02.12. Juxtamembrane peptide of epidermal growth factor receptor 1z9i Eukaryo. plasma 1 0 4.7 ± 1.6 78 ± 5 -7.1
2.1.01.01. Phospholipase A2, group X 1le6 Secreted 1 0 7.4 ± 0.9 78 ± 6 -13.2
3.1.11.02. Glucagon analog 1bh0 Secreted 1 0 4.9 ± 4.2 78 ± 2 -6.1
3.2.08.01. Peptide 35-42, alternate polymorph II 2y3l Secreted 4 0 2.7 ± 1.4 78 ± 8 -6.0
2.1.18.01. Annexin VIII 1w3w Eukaryo. plasma 1 0 4.1 ± 1.0 79 ± 9 -6.2
2.1.53.01. Peroxisomal biogenesis factor 19 2wl8 Peroxisome 1 0 8.3 ± 0.8 79 ± 14 -9.9
2.1.18.01. Annexin V 1hvf Eukaryo. plasma 1 0 2.3 ± 1.5 79 ± 10 -5.4
1.2.32.01. Cytochrome P450 1B1 3pm0 Endoplasm. reticulum 1 0 3.8 ± 0.7 79 ± 1 -7.0
1.2.32.01. Cytochrome P450 2C9 1og5 Endoplasm. reticulum 1 0 7.6 ± 1.0 79 ± 6 -13.7
2.2.20.01. Son of sevenless homolog 1 (SOS-1) 1xd4 Eukaryo. plasma 1 0 1.9 ± 3.0 79 ± 2 -4.5
2.3.15.01. Electron transfer flavoprotein 1efv Mitochon. inner 2 0 4.6 ± 1.3 79 ± 12 -4.6
3.1.11.02. Vasoactive intestinal peptide 2rrh Secreted 1 0 4.1 ± 0.3 79 ± 9 -5.7
2.3.06.08. Pancreatic lipase-related protein 1 2ppl Secreted 1 0 7.1 ± 0.9 79 ± 6 -10.2
3.1.30.01. Lactoferrin-based peptide, 39-49 2gmc Secreted 1 0 3.9 ± 1.7 79 ± 13 -4.6
2.2.41.01. Beta-defensin 2 1fd3 Secreted 1 0 5.2 ± 1.2 80 ± 12 -9.1
1.2.25.01. Phospholamban, cytoplasmic helix 1plp Endoplasm. reticulum 1 0 4.0 ± 1.3 80 ± 4 -7.2
2.4.20.01. Cathepsin F 1m6d Lysosome 1 0 4.3 ± 0.8 80 ± 3 -11.7
2.2.20.01. Rho guanine nucleotide exchange factor 4 2dx1 Eukaryo. plasma 1 0 2.2 ± 2.2 80 ± 10 -3.6
2.3.18.01. Carnitine O-palmitoyltransferase 1, liver isoform, N-terminal domain 2le3 Mitochon. outer 1 0 3.9 ± 3.7 80 ± 3 -9.3
1.2.01.01. Fibroblast growth factor receptor 2 complex 3oj2 Secreted 6 0 2.0 ± 0.4 81 ± 3 -5.4
2.4.09.01. Serine/threonine-protein kinase Nek2 2w5a Eukaryo. plasma 1 0 2.7 ± 1.5 81 ± 6 -11.2
2.2.41.01. Alpha-defensin 2 1zmi Secreted 1 0 2.3 ± 1.1 81 ± 17 -3.7
3.4.09.01. Granin 1lv4 Secreted 1 0 1.8 ± 0.4 81 ± 3 -6.8
3.3.02.01. Collagen alpha-1(III) complex 2v53 Secreted 4 0 5.4 ± 1.3 81 ± 0 -8.8
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, more complete 4ezk Eukaryo. plasma 1 0 3.6 ± 0.6 81 ± 2 -5.1
2.3.06.01. Bile-salt activated lipase, structure 1 1f6w Secreted 1 0 1.8 ± 0.5 81 ± 10 -5.1
2.3.06.08. Pancreatic lipase, complex with colipase from Pig 1lpa Secreted 2 0 11.3 ± 0.1 82 ± 1 -24.5
2.4.07.01. Nischarin 3p0c Endosome 1 0 4.1 ± 0.5 82 ± 13 -7.0
2.2.12.02. Rho GDP-dissociation inhibitor 2, complex with G-protein RAC2 1ds6 Eukaryo. plasma 2 0 2.8 ± 1.0 82 ± 6 -5.5
2.3.05.04. Reticulon-4-interacting protein 1 2vn8 Mitochon. inner 1 0 4.0 ± 0.0 82 ± 0 -10.2
2.1.18.01. Annexin IV 2zoc Eukaryo. plasma 1 0 3.4 ± 1.1 82 ± 7 -7.6
2.1.18.01. Annexin VI 1m9i Eukaryo. plasma 1 0 2.8 ± 0.3 82 ± 0 -8.5
2.1.24.01. Saposin C (peptide 311-391) 1sn6 Lysosome 1 0 4.8 ± 1.1 82 ± 7 -7.1
2.4.06.01. Lipid transport protein Mln64 (StARD3) 1em2 Endosome 1 0 2.0 ± 1.1 82 ± 12 -5.0
3.1.02.08. High affinity copper uptake protein 1, peptide 156-179 2ls4 Eukaryo. plasma 1 0 4.9 ± 0.7 82 ± 10 -6.5
1.2.04.01. Integrin beta-1, complex with talin-2 3g9w Eukaryo. plasma 2 0 8.7 ± 2.5 83 ± 6 -6.6
2.1.59.01. Squalene synthase, conformation 1 3v66 Endoplasm. reticulum 1 0 3.1 ± 0.8 83 ± 6 -5.1
2.1.41.01. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 3ml9 Eukaryo. plasma 1 0 3.0 ± 0.8 83 ± 2 -6.0
2.2.20.01. Rac-beta serine/threonine protein kinase 1p6s Eukaryo. plasma 1 0 3.8 ± 1.8 83 ± 11 -5.7
2.4.07.01. PX domain of C2alpha-PI3 kinase 2ar5 Eukaryo. plasma 1 0 5.6 ± 0.9 83 ± 17 -3.7
3.1.04.02. Major prion protein, peptide 173-195 2iv5 Eukaryo. plasma 1 0 5.3 ± 4.1 83 ± 17 -3.5
3.2.08.02. Major prion protein, peptide 138-143 3nvf Eukaryo. plasma 10 0 6.9 ± 0.2 83 ± 2 -9.8
2.3.06.01. Neuroligin-4, X-linked, complex with neurexin 1-beta 2xb6 Eukaryo. plasma 2 0 1.9 ± 3.0 84 ± 11 -3.3
2.2.41.01. Alpha-defensin 5 1zmp Secreted 1 0 4.2 ± 1.6 84 ± 14 -2.8
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 436-456 1bts Eukaryo. plasma 1 0 9.2 ± 0.3 84 ± 2 -14.8
3.1.11.01. Peptide YY 2dez Secreted 1 0 4.0 ± 0.2 84 ± 2 -5.9
1.2.03.04. Leukocyte immunoglobulin-like receptor subfamily B member 4 3p2t Eukaryo. plasma 1 0 1.7 ± 0.4 84 ± 5 -5.9
1.2.07.01. Protein jagged-1 2vj2 Eukaryo. plasma 1 0 3.4 ± 1.8 84 ± 8 -5.8
2.2.41.01. Neutrophil defensin 1, dimer 3gny Secreted 2 0 3.5 ± 0.5 84 ± 6 -5.0
3.1.30.01. Lactoferrin-based peptide, 21-67 1z6v Secreted 1 0 1.7 ± 1.4 84 ± 3 -4.9
2.1.29.05. Apolipoprotein C-III 2jq3 Secreted 1 0 2.9 ± 1.4 85 ± 0 -5.6
3.1.11.02. Glucagon analog, lipidated 2m5p Secreted 1 0 5.2 ± 0.6 85 ± 4 -6.0
2.3.06.01. Bile-salt activated lipase, structure 2 1jmy Secreted 1 0 5.0 ± 1.4 85 ± 9 -5.3
2.1.14.01. Peroxisomal targeting signal 1 receptor, complex with sterol carrier protein 2 2c0l Peroxisome 2 0 3.1 ± 2.5 85 ± 35 -5.5
2.1.10.01. Glycolipid transfer protein, conformation 1 1sx6 Eukaryo. plasma 1 0 4.3 ± 1.1 85 ± 5 -10.1
1.2.44.01. Amyloid beta A4 protein (peptide 672-711) 1ba4 Eukaryo. plasma 1 0 6.0 ± 0.3 85 ± 5 -10.9
3.1.03.01. Myc box-dependent-interacting protein 1, membrane anchor helix (peptide 1-33) 2rnd Eukaryo. plasma 1 0 4.0 ± 0.4 85 ± 2 -8.4
2.2.41.01. Neutrophil defensin 1 2pm1 Secreted 1 0 3.6 ± 1.3 85 ± 6 -3.8
1.2.39.02. Stromelysin-1 1c3i Eukaryo. plasma 1 0 3.6 ± 1.7 85 ± 17 -4.4
2.2.11.01. C2 domain of E3 ubiquitin-protein ligase NEDD4-like 2nsq Eukaryo. plasma 1 0 1.8 ± 1.1 85 ± 5 -3.3
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 1 2q9f Endoplasm. reticulum 1 0 2.8 ± 1.0 86 ± 7 -5.8
3.1.04.02. Major prion protein, peptide 110-136 2lbg Eukaryo. plasma 1 0 5.0 ± 7.0 86 ± 1 -9.3
3.1.29.01. Cathelicidin LL-37 2k6o Secreted 1 0 8.1 ± 0.4 86 ± 8 -15.7
2.1.29.03. Apolipoprotein C-I, peptide 61-79 1alf Secreted 1 0 4.1 ± 0.5 86 ± 3 -9.4
2.4.09.01. Death-associated protein kinase 1 2w4j Eukaryo. plasma 1 0 2.1 ± 0.7 86 ± 12 -4.1
2.1.54.01. Programmed cell death protein 10 3ajm Golgi 2 0 2.7 ± 0.4 86 ± 7 -5.8
3.2.08.01. Peptide 30-35 2y3j Secreted 4 0 4.0 ± 1.4 86 ± 6 -6.2
2.1.51.01. Protein farnesyltransferase/geranylgeranyltransferase 2h6f Eukaryo. plasma 2 0 4.5 ± 1.5 87 ± 6 -6.5
2.2.20.01. PH domain of TAPP1 1eaz Eukaryo. plasma 1 0 1.7 ± 1.6 87 ± 14 -3.0
2.2.12.02. Rho GDP-dissociation inhibitor 1, complex with cell division control protein 42 1doa Eukaryo. plasma 2 0 1.1 ± 1.3 87 ± 4 -3.1
2.1.29.02. Apolipoprotein A-II 2ou1 Secreted 2 0 2.7 ± 1.2 87 ± 2 -17.7
2.2.03.01. Cathepsin D 1lyb Lysosome 2 0 7.0 ± 0.6 87 ± 5 -11.2
2.1.10.01. Glycolipid transfer protein, conformation 2 1swx Eukaryo. plasma 1 0 4.6 ± 1.0 87 ± 8 -7.1
2.1.29.01. Apolipoprotein A-I, alternative structure of C-terminal domain 3r2p Secreted 2 0 1.7 ± 1.6 87 ± 3 -4.1
3.1.06.01. Apolipoprotein A-I, peptide 190-209 1odq Undefined 1 0 3.3 ± 0.7 87 ± 4 -7.1
2.2.41.01. Neutrophil defensin 3 1dfn Secreted 2 0 1.4 ± 1.3 87 ± 15 -3.9
2.3.18.01. Choline O-acetyltransferase 2fy2 Eukaryo. plasma 1 0 1.5 ± 2.2 87 ± 17 -5.2
2.1.32.01. Alpha-synuclein 1xq8 Eukaryo. plasma 1 0 8.7 ± 1.1 87 ± 4 -15.7
2.1.18.01. Annexin II 1w7b Eukaryo. plasma 1 0 2.4 ± 1.2 87 ± 18 -3.8
3.1.13.01. Islet amyloid polypeptide, fragment 34-70 2l86 Secreted 1 0 6.2 ± 0.8 88 ± 7 -9.6
3.1.06.01. Apolipoprotein E, peptide 281-304 1oef Undefined 1 0 4.8 ± 0.9 88 ± 19 -5.5
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Endosome 1 0 2.4 ± 1.6 88 ± 12 -4.6
2.2.12.02. Rho GDP-dissociation inhibitor 1, complex with G-protein RAC2 1hh4 Eukaryo. plasma 2 0 4.0 ± 0.6 88 ± 6 -7.2
1.2.03.02. SLAM family member 6 2if7 Eukaryo. plasma 3 0 2.0 ± 3.3 88 ± 11 -7.1
3.2.08.01. Peptide KLVFFA from amyloid beta, alternate polymorph II 3ow9 Secreted 12 0 4.1 ± 1.4 88 ± 7 -12.8
2.2.20.01. Dynamin-1 1dyn Eukaryo. plasma 2 0 4.1 ± 1.2 88 ± 15 -9.7
2.4.08.01. Eosinophil cationic protein 1h1h 1 0 3.5 ± 1.0 88 ± 6 -7.3
2.4.09.01. Calcium/calmodulin-dependent protein kinase type IV 2w4o Eukaryo. plasma 1 0 3.2 ± 1.2 88 ± 6 -5.6
2.1.01.01. Phospholipase A2, group IIA 1n28 Secreted 1 0 3.6 ± 0.6 88 ± 4 -7.0
2.2.11.01. Synaptotagmin-13 1wfm Eukaryo. plasma 1 0 2.2 ± 1.9 88 ± 15 -4.5
3.2.08.01. Amyloid beta A4 protein, peptide 672-711 2lnq Eukaryo. plasma 8 0 6.3 ± 2.0 88 ± 0 -15.5
3.1.13.01. Proadrenomedullin N-20 terminal peptide 2fly Secreted 1 0 4.8 ± 4.0 88 ± 2 -7.5
2.3.06.08. Pancreatic lipase-related protein 2 2oxe Secreted 1 0 10.2 ± 1.1 88 ± 8 -10.1
2.1.02.01. Arachidonate 5-lipoxygenase, complex with arachidonic acid 3v99 Eukaryo. plasma 1 0 3.0 ± 2.3 88 ± 9 -2.5
2.1.24.01. Saposin D (peptide 405-486) 2rb3 Secreted 1 0 2.2 ± 1.7 88 ± 10 -3.4
1.2.22.01. Activator of apoptosis harakiri, cytosolic helix 2l58 Mitochon. outer 1 0 2.4 ± 4.0 88 ± 0 -8.5
3.2.08.01. Peptide 35-42, alternate polymorph I 2y3k Secreted 2 0 3.4 ± 1.4 89 ± 4 -7.2
3.1.14.01. Neurokinin B 1p9f Secreted 1 0 5.8 ± 1.2 89 ± 18 -6.8
3.2.03.01. Hepcidin 1m4e Secreted 1 0 2.4 ± 1.5 89 ± 19 -4.2
2.1.02.01. Arachidonate 5-lipoxygenase 3o8y Eukaryo. plasma 1 0 2.1 ± 1.0 89 ± 4 -3.8
3.1.02.09. Peptide (686-738) of platelet endothelial cell adhesion molecule 2ky5 Eukaryo. plasma 1 0 1.0 ± 3.8 89 ± 3 -3.7
2.1.24.01. Saposin A (peptide 60-140), conformation in disc 4ddj Lysosome 1 0 6.4 ± 0.9 89 ± 3 -8.5
2.2.11.01. Synaptotagmin-1 C2A-C2B domains 2r83 Eukaryo. plasma 1 0 3.0 ± 1.9 89 ± 10 -3.8
2.3.04.01. Corticosteroid 11-beta-dehydrogenase, isozyme 1 1xu7 Endoplasm. reticulum 2 0 7.9 ± 0.2 89 ± 1 -20.2
2.3.12.01. Myotubularin-related protein 2 1zvr Eukaryo. plasma 1 0 3.1 ± 0.4 89 ± 8 -5.0
2.3.01.01. Glucosylceramidase 1ogs Lysosome 1 0 4.2 ± 1.1 89 ± 4 -9.0
2.3.06.08. Pancreatic lipase, complex with colipase from Pig 1lpb Secreted 2 0 9.2 ± 0.4 89 ± 2 -24.2
2.2.02.01. Serine protease HTRA1 3nzi Secreted 6 0 4.2 ± 0.7 90 ± 0 -11.8
3.1.11.02. Glucagon-like peptide 2 2l64 Secreted 1 0 3.9 ± 0.3 90 ± 5 -10.8
3.1.13.01. Islet amyloid polypeptide, fragment 34-70 2kb8 Secreted 1 0 3.9 ± 4.2 90 ± 1 -10.2
3.1.11.02. Pituitary adenylate cyclase activating polypeptide (PACAP)-38 2d2p Secreted 1 0 3.9 ± 4.0 90 ± 0 -6.8
2.4.30.01. TNF receptor-associated factor 2 1d01 Eukaryo. plasma 3 0 3.5 ± 0.0 90 ± 0 -5.7
3.1.04.04. Peptide of huntigtin, 1-17 2ld2 Eukaryo. plasma 1 0 4.2 ± 0.6 90 ± 4 -9.3
2.3.11.01. Ferrochelatase 1hrk Mitochon. inner 2 0 2.7 ± 0.1 90 ± 0 -9.9
2.1.35.01. Protein kinase C and casein kinase substrate 3qni Eukaryo. plasma 2 0 3.0 ± 0.0 90 ± 0 -6.4
3.1.31.01. Dermcidin, crystal structure 2ymk Secreted 1 0 4.4 ± 7.0 90 ± 0 -30.3
2.1.11.01. Alpha-actinin-2 1hci Eukaryo. plasma 2 0 0.4 ± 0.7 90 ± 12 -5.1
2.2.20.01. PH domain of tyrosine-protein kinase BTK 1bwn Eukaryo. plasma 2 0 15.3 ± 0.5 90 ± 10 -33.3
2.2.09.01. Kelch-like protein 7 3ii7 Undefined 1 0 2.6 ± 1.8 90 ± 16 -6.5