PDB ID or protein name

Hepatitis C virus (18 proteins)

Family Protein Name PDB ID Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
1.1.79.01. P7 protein (747-809), structure 2 2mts Endoplasm. reticulum 1 2 28.6 ± 2.1 8 ± 2 -26.1
1.1.79.01. P7 protein (747-809), structure 1 3zd0 Endoplasm. reticulum 1 2 29.2 ± 4.2 12 ± 5 -15.3
1.1.81.01. P7 viral protein 2m6x Endoplasm. reticulum 6 12 26.8 ± 0.1 1 ± 0 -35.4
2.2.02.02. HCV serine protease NS3 3p8n Endoplasm. reticulum 2 0 8.7 ± 1.7 56 ± 8 -9.9
2.2.02.02. Hepatitis C virus NS3 protease 2o8m Endoplasm. reticulum 4 0 5.0 ± 1.3 72 ± 8 -9.0
2.2.54.01. Non-structural protein 5A 3fqm Endoplasm. reticulum 1 0 4.9 ± 1.1 77 ± 7 -7.5
2.4.41.01. Hepatitis C virus non-structural protein NS2 (955-1026) 2hd0 Endoplasm. reticulum 2 0 6.7 ± 0.6 85 ± 0 -11.8
3.1.01.03. Viral core-E1 signal peptide 2lif Viral 1 1 29.6 ± 5.0 19 ± 10 -16.6
3.1.07.02. Juxtamembrane peptide (684-719) of protein gp41 2kzq Endosome 1 0 4.3 ± 3.3 88 ± 0 -9.9
3.1.07.04. Envelope glycoprotein E1, heterodimerization peptide (350-370) 1emz Viral 1 0 6.2 ± 0.2 86 ± 9 -8.5
3.1.07.04. Juxtamembrane peptide of hepatis C virus E1 glycoprotein (314-342) 2knu Endosome 1 0 5.3 ± 0.9 82 ± 6 -5.9
3.1.07.05. Nonstructural protein 4b, segment 1938-1965 of polyprotein 2kdr Endoplasm. reticulum 1 1 22.4 ± 2.0 48 ± 2 -19.1
3.1.07.05. Nonstructural protein 4b, segment 1751-1780 2jxf Endoplasm. reticulum 1 0 5.6 ± 3.6 85 ± 2 -10.6
3.1.07.05. Nonstructural protein 4b, segment 1716-1755 2lvg Viral 1 0 6.4 ± 0.7 82 ± 8 -11.4
3.1.07.05. Nonstructural protein 5b, segment 2982-3011 2n1p Eukaryo. plasma 1 1 24.0 ± 2.5 21 ± 3 -16.1
3.1.07.06. NS2 protease, segment 836-868 of polyprotein 2kwt Endoplasm. reticulum 1 0 9.5 ± 3.6 81 ± 3 -15.7
3.1.07.06. NS2 protease, segment 869-908 of polyprotein 2kwz Endoplasm. reticulum 1 1 29.8 ± 1.6 59 ± 7 -15.7
3.1.07.06. NS2 protease, segment 810-837 of polyprotein 2jy0 Endoplasm. reticulum 1 1 23.8 ± 2.9 14 ± 4 -11.4