PDB ID or protein name

Alpha-helical peptides superfamilies

3.1.01. Peptide hormones (6 families)
3.1.02. Endothelin-like (1 family)
3.1.03. Major surface glycoprotein G (1 family)
3.1.04. Synuclein (1 family) 1.C.77 (TCDB)
3.1.05. Magainin (1 family) 1.C.16 (TCDB)
3.1.06. Peptaibol (1 family) 1.D.5 (TCDB)
3.1.07. Moricin (1 family) 1.C.17 (TCDB)
3.1.08. Tachykinin peptides (1 family)
3.1.09. Antimicrobial peptide HP (1 family)
3.1.10. Insect toxins (3 families)
3.1.11. Alpha-conotoxins (1 family)
3.1.12. Pleurocidin (1 family) 1.C.62 (TCDB)
3.1.13. Nonstructural protein 5a, anchor domain (1 family)
3.1.14. Model peptides (1 family)

Alpha-helical peptides (36 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
3.1.01.01. Neuropeptide Y analogue 1icy Sus scrofa Secreted 1 0 5.9 ± 1.1 68 ± 15 -9.4
3.1.01.02. Glucagon 1gcn Sus scrofa Secreted 1 0 5.1 ± 1.5 75 ± 16 -5.7
3.1.01.03. Motilin 1lbj Homo sapiens Secreted 1 0 9.0 ± 1.2 44 ± 14 -3.4
3.1.01.04. Transportan 1smz Designed proteins Secreted 1 0 4.2 ± 1.2 88 ± 14 -11.2
3.1.01.05. Neurokinin B 1p9f Homo sapiens Secreted 1 0 7.5 ± 1.8 86 ± 16 -8.7
3.1.01.06. Orexin-A 1wso Homo sapiens Secreted 1 0 9.6 ± 1.3 66 ± 17 -6.9
3.1.02.01. Endothelin-1 1edn Homo sapiens Secreted 1 0 4.1 ± 1.6 45 ± 8 -5.1
3.1.03.01. Major surface glycoprotein G fragment 1brv Bovine respiratory syncytial virus Viral 1 0 7.5 ± 1.2 84 ± 16 -4.5
3.1.04.01. Alpha-synuclein 1xq8 Homo sapiens Eukaryo. plasma 1 0 17.9 ± 1.0 85 ± 11 -22.8
3.1.05.01. Magainin 2 2mag Xenopus laevis Secreted 1 0 10.1 ± 1.0 79 ± 5 -14.5
3.1.06.01. Cephaibol B 1ob6 Acremonium tubakii Secreted 1 0 11.6 ± 1.6 86 ± 15 -36.6
3.1.06.01. Cephaibol C 1ob7 Acremonium tubakii Secreted 1 0 13.5 ± 1.4 61 ± 19 -19.9
3.1.06.01. Antiamoebin I 1joh Emercelliopsis sp. Secreted 1 0 14.4 ± 1.6 61 ± 20 -16.4
3.1.06.01. Alamethicin 1amt Trichoderma viride Secreted 2 2 28.1 ± 0.0 16 ± 8 -38.0
3.1.06.01. Zervamicin IIb 1ih9 Emericellopsis salmosynnemata Secreted 1 0 9.9 ± 1.0 78 ± 15 -14.3
3.1.06.01. Chrysospermin C 1ee7 Apiocrea chrysosperma Secreted 1 1 25.0 ± 0.0 20 ± 8 -18.1
3.1.06.01. Trichotoxin a50e 1m24 Trichoderma viride Secreted 1 0 10.7 ± 1.1 76 ± 18 -20.9
3.1.06.01. Cephaibol A 1ob4 Acremonium tubakii Secreted 1 0 14.6 ± 1.5 60 ± 20 -19.2
3.1.07.01. Moricin 1x22 Spodoptera litura Secreted 1 0 4.2 ± 1.0 69 ± 11 -10.9
3.1.07.01. Moricin 1kv4 Bombyx mori Secreted 1 0 7.2 ± 1.3 73 ± 13 -11.9
3.1.08.01. Kassinin 1myu Kassina senegalensis Secreted 1 0 3.6 ± 1.2 58 ± 20 -4.0
3.1.08.01. Eledoisin 1mxq Eledone moschata Secreted 1 0 9.9 ± 1.7 21 ± 20 -6.2
3.1.08.01. Neurokinin A 1n6t Gallus gallus Secreted 1 0 8.8 ± 1.6 22 ± 20 -4.3
3.1.09.01. Antimicrobial peptide HP 1p0l Helicobacter pylori Secreted 1 0 4.0 ± 1.0 75 ± 12 -6.3
3.1.10.01. Poneratoxin 1g92 Paraponera clavata Secreted 1 0 17.9 ± 1.6 35 ± 20 -23.0
3.1.10.02. Mastoparan 2czp Vespa xanthoptera Secreted 1 0 4.2 ± 1.1 85 ± 17 -1.0
3.1.10.02. Mastoparan-L 1d7n Vespula lewisii Secreted 1 0 7.7 ± 0.9 79 ± 9 -10.2
3.1.10.03. Plantaricin-A 1ytr Lactobacillus plantarum Secreted 1 0 9.5 ± 1.1 82 ± 13 -8.1
3.1.11.01. alpha-conotoxin PNI1 1pen Conus pennaceus Secreted 1 0 4.9 ± 2.0 43 ± 20 -4.7
3.1.11.01. alpha-conotoxin PNIB 1akg Conus pennaceus Secreted 1 0 4.3 ± 2.0 49 ± 20 -6.9
3.1.11.01. alpha-conotoxin MII 1mii Conus magus Secreted 1 0 2.6 ± 1.2 59 ± 17 -5.3
3.1.11.01. alpha-conotoxin auIB 1dg2 Conus aulicus Secreted 1 0 5.2 ± 1.7 67 ± 20 -4.0
3.1.12.01. Pleurocidin 1z64 Pseudopleuronectes americanus Secreted 1 0 10.7 ± 1.3 76 ± 19 -13.8
3.1.13.01. Nonstructural protein 5a, anchor domain, structure in micelles 1r7g Human hepatitis C virus Endoplasm. reticulum 1 0 4.9 ± 0.6 98 ± 6 -12.6
3.1.13.01. Nonstructural protein 5a, anchor domain, structure in micelles 2ajo Bovine viral diarrhea virus Endoplasm. reticulum 1 0 5.0 ± 1.2 88 ± 19 -11.7
3.1.14.01. Amphipathic alpha-helix of apolipoprotein 2irg Designed proteins Secreted 1 0 6.3 ± 1.0 86 ± 11 -13.1