PDB ID or protein name

Nonregular peptides superfamilies

3.4.01. Gramicidin S (1 family)
3.4.02. Lantibiotic peptides (4 families) 1.C.20 (TCDB)
3.4.03. Heat-stable enterotoxin (1 family)
3.4.04. Cyclic lipopeptide antibiotics (1 family)
3.4.05. Cyclosporin (1 family)

Nonregular peptides (14 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
3.4.01.01. Gramicidin S 1tk2 Bacillus brevis Secreted 1 0 13.0 ± 1.5 81 ± 20 -14.1
3.4.02.01. Actagardine, structure in acetonitrile solution 1aj1 Actinoplanes liguriae Secreted 1 0 6.3 ± 1.6 72 ± 18 -6.5
3.4.02.02. Mersacidin, crystal structure 1qow Bacillus sp. Secreted 3 0 7.7 ± 1.0 89 ± 13 -17.6
3.4.02.02. Mersacidin, structure in methanol solution 1mqx Bacillus sp. Secreted 1 0 2.4 ± 1.3 77 ± 20 -2.3
3.4.02.02. Mersacidin, structure in DPC micelles 1mqy Bacillus sp. Secreted 1 0 11.5 ± 1.8 56 ± 20 -9.5
3.4.02.02. Mersacidin, structure of lipid II bound peptide in DPC micelles 1mqz Bacillus sp. Secreted 1 0 3.5 ± 1.8 81 ± 19 -4.9
3.4.02.03. Nisin-Lipid II complex in DMSO solution 1wco Lactococcus lactis Secreted 1 0 8.8 ± 1.5 89 ± 19 -4.0
3.4.02.04. Cinnamycin 2dde Streptoverticillium griseoverticillatum Secreted 1 0 3.7 ± 1.5 38 ± 11 -6.2
3.4.03.01. Heat-stable enterotoxin ST-IA/ST-P 1etn Escherichia coli Secreted 1 0 2.5 ± 1.7 21 ± 20 -2.3
3.4.04.01. Tsushimycin 1w3m Streptomyces pseudogriseolus Secreted 2 0 5.4 ± 0.7 88 ± 12 -14.8
3.4.04.01. Daptomycin, Ca-free 1t5m Streptomyces roseosporus Secreted 1 0 3.3 ± 1.4 21 ± 15 -8.7
3.4.04.01. Daptomycin, Ca-free 1xt7 Streptomyces roseosporus Secreted 1 0 4.8 ± 1.8 28 ± 19 -7.2
3.4.04.01. Daptomycin, Ca-bound 1t5n Streptomyces roseosporus Secreted 1 0 4.9 ± 1.6 58 ± 18 -9.8
3.4.05.01. Cyclosporin 1cwa Tolypocladium inflatum Secreted 1 0 9.7 ± 2.0 47 ± 20 -15.3