PDB ID or protein name

All beta monotopic/peripheral superfamilies

2.2.01. Signal peptidase (1 family)
2.2.02. Trypsin-like serine proteases (3 families)
2.2.03. Acid proteases (1 family)
2.2.04. Retinal pigment epithelial membrane protein (1 family)
2.2.05. Cupredoxins (1 family)
2.2.06. Lipocalins (2 families) 8.A.33 (TCDB)
2.2.07. Streptavidin-like (1 family)
2.2.08. Osmotin, thaumatin-like protein (1 family)
2.2.09. Ganglioside GM2 activator (1 family)
2.2.10. High potential iron protein (1 family)
2.2.11. C2 domain (2 families)
2.2.12. E set domains (4 families)
2.2.13. Clathrin adaptor appendage domain (1 family)
2.2.14. Galactose-binding domain-like (1 family)
2.2.15. Methuselah ectodomain (1 family)
2.2.16. Lipoprotein localization factors (1 family)
2.2.17. Cystine-knot cytokines (2 families)
2.2.18. Viral glycoprotein (1 family) 1.G.3 (TCDB)
2.2.19. Adsorption protein p2 (1 family)
2.2.20. PH domain-like (3 families)
2.2.21. Actin cross-linking proteins (1 family)
2.2.22. Hydrophobin (1 family)
2.2.24. Vitelline membrane outer protein-I (1 family)
2.2.25. SH2 domain (1 family)
2.2.26. FYVE/PHD zinc finger (1 family)
2.2.27. C1 domain (1 family)
2.2.28. Gurmarin-like (1 family)
2.2.29. Agouti-related protein (1 family)
2.2.30. Elafin-like (1 family)
2.2.31. Kringle-like (1 family)
2.2.32. Anemone pore-forming cytolysin (1 family) 1.C.38 (TCDB)
2.2.33. STI-like (2 families)
2.2.34. Omega conotoxin-like (4 families)
2.2.35. Perfringolysin (1 family) 1.C.12 (TCDB)
2.2.36. Cyclotides (4 families)
2.2.37. Scorpion toxin-like (4 families)
2.2.38. Cloacin translocation domain (1 family)
2.2.39. Snake toxin-like (2 families) 1.C.74 (TCDB)
2.2.40. Neurotoxin III (1 family)
2.2.41. Defensin-like (2 families)
2.2.42. Pneumovirus matrix protein (1 family)
2.2.43. Galactose mutarotase-like (1 family)

All beta monotopic/peripheral (227 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.2.01.01. Type 1 signal peptidase, complex with lipopeptide inhibitor 1t7d Escherichia coli Bact. gram-neg inner 1 0 3.7 ± 1.0 66 ± 3 -5.9
2.2.01.01. Type 1 signal peptidase, complex with inhibitor 1b12 Escherichia coli Bact. gram-neg inner 1 0 2.4 ± 2.0 88 ± 18 -2.4
2.2.01.01. Type 1 signal peptidase, apo-enzyme 1kn9 Escherichia coli Bact. gram-neg inner 1 0 4.5 ± 1.2 83 ± 6 -4.5
2.2.02.01. Mitochondrial serine protease HtrA2 1lcy Homo sapiens Mitochon. inner 1 0 8.0 ± 1.7 79 ± 15 -4.0
2.2.02.01. Exfoliative toxin B 1qtf Staphylococcus aureus Secreted 1 0 2.4 ± 1.8 80 ± 10 -3.1
2.2.02.02. Procarboxypeptidase A-S6 subunit III 1fon Bos taurus Eukaryo. plasma 2 0 1.4 ± 0.7 88 ± 5 -4.8
2.2.02.02. Chymotrypsinogen B 1kdq Rattus norvegicus Eukaryo. plasma 1 0 2.8 ± 2.0 75 ± 17 -3.6
2.2.02.03. NS3 protease 1dy9 Human hepatitis C virus Secreted 1 0 6.1 ± 1.8 62 ± 12 -10.5
2.2.02.03. NS3 protease, dimer 1n1l Human hepatitis C virus Secreted 2 0 5.8 ± 1.3 70 ± 9 -10.3
2.2.02.03. NS3 protease, complex with Bowman-Birk inhibitor 1df9 Dengue virus Secreted 3 0 2.1 ± 0.5 88 ± 6 -4.7
2.2.02.03. NS3 protease 1bef Dengue virus Secreted 1 0 3.0 ± 1.1 78 ± 10 -4.1
2.2.03.01. Cathepsin D 1lyb Homo sapiens Lysosome 2 0 5.7 ± 1.0 90 ± 7 -10.6
2.2.03.01. Phytepsin 1qdm Hordeum vulgare Vacuole 1 0 11.2 ± 0.7 85 ± 6 -9.3
2.2.03.01. Plasmepsin IV 1qs8 Plasmodium vivax Vacuole 1 0 8.6 ± 0.8 74 ± 10 -6.9
2.2.04.01. Lignostilbene-alpha,beta-dioxygenase (retinal-forming oxygenase) 2biw Synechocystis sp. Bact. gram-neg inner 1 0 5.1 ± 0.5 40 ± 9 -12.7
2.2.04.01. Retinal pigment epitelium-specific 65 kDa protein 3fsn Bos taurus Eukaryo. plasma 1 0 7.6 ± 0.7 78 ± 5 -7.3
2.2.05.01. Amicyanin 1sfd Paracoccus denitrificans Bact. gram-neg inner 1 0 3.5 ± 0.8 55 ± 8 -3.3
2.2.05.01. Amicyanin 1id2 Paracoccus versutus Bact. gram-neg inner 1 0 3.6 ± 0.6 59 ± 5 -5.3
2.2.05.01. Plastocyanin 9pcy Phaseolus vulgaris Thylakoid 1 0 1.1 ± 1.7 25 ± 17 -1.3
2.2.05.01. Pseudoazurin 1pmy Methylobacterium extorquens Bact. gram-neg inner 1 0 2.5 ± 1.5 43 ± 12 -4.6
2.2.05.01. Plastocyanin 2plt Chlamydomonas reinhardtii Thylakoid 1 0 1.6 ± 1.4 37 ± 19 -1.3
2.2.05.01. Azurin I 1rkr Alcaligenes xylosoxidans Bact. gram-neg inner 1 0 1.7 ± 0.9 43 ± 7 -4.5
2.2.05.01. Plastocyanin 1bxv Synechocystis sp. Thylakoid 1 0 1.7 ± 1.9 36 ± 17 -1.4
2.2.05.01. Azurin iso-2 1cuo Methylomonas sp. Bact. gram-neg inner 1 0 3.3 ± 1.8 50 ± 20 -3.8
2.2.05.01. Plastocyanin 1b3i Prochlorothrix hollandica Thylakoid 1 0 2.3 ± 1.7 42 ± 13 -3.0
2.2.05.01. Plantacyanin 1f56 Spinacia oleracea Thylakoid 1 0 1.8 ± 2.0 5 ± 19 -1.4
2.2.06.01. Retinol binding protein 1rlb Gallus gallus Secreted 1 0 2.7 ± 1.0 78 ± 9 -4.4
2.2.06.01. Retinol binding protein, plasma isoform 1iiu Gallus gallus Secreted 1 0 2.3 ± 2.0 40 ± 17 -3.4
2.2.06.01. Outer membrane lipoprotein Blc 1qwd Escherichia coli Bact. gram-neg outer 1 0 1.6 ± 1.2 88 ± 19 -3.0
2.2.06.01. Retinol binding protein 1kt6 Bos taurus Secreted 1 0 3.5 ± 1.3 79 ± 10 -4.5
2.2.06.01. Retinol binding protein 1aqb Sus scrofa Secreted 1 0 3.4 ± 1.1 81 ± 13 -4.6
2.2.06.01. Retinol binding protein 1rbp Homo sapiens Secreted 1 0 3.1 ± 1.5 75 ± 10 -5.8
2.2.06.02. Brain fatty acid binding protein 1fdq Homo sapiens Eukaryo. plasma 1 0 3.2 ± 1.0 53 ± 18 -2.2
2.2.06.02. Cellular retinol-binding protein II 1crb Rattus norvegicus Eukaryo. plasma 1 0 2.2 ± 1.2 62 ± 17 -3.3
2.2.06.02. Epidermal fatty acid binding protein 1b56 Homo sapiens Eukaryo. plasma 1 0 2.2 ± 1.1 53 ± 15 -2.8
2.2.06.02. Cellular retinol-binding protein II 1kqw Danio rerio Eukaryo. plasma 1 0 2.0 ± 1.5 41 ± 16 -3.4
2.2.06.02. Adipocyte lipid-binding protein 1g7n Mus musculus Eukaryo. plasma 1 0 2.1 ± 1.4 41 ± 18 -2.5
2.2.06.02. Cellular retinol-binding protein III 1ggl Homo sapiens Eukaryo. plasma 1 0 3.5 ± 1.6 43 ± 15 -5.5
2.2.06.02. Adipocyte lipid-binding protein 1tow Homo sapiens Eukaryo. plasma 1 0 1.9 ± 1.8 46 ± 18 -2.6
2.2.06.02. P2 myelin protein 1pmp Bos taurus Eukaryo. plasma 1 0 2.4 ± 1.1 58 ± 17 -3.9
2.2.06.02. Muscle fatty acid binding protein 1hmt Homo sapiens Eukaryo. plasma 1 0 4.4 ± 1.2 45 ± 13 -2.3
2.2.06.02. Fatty acid-binding protein homolog 1 1o8v Echinococcus granulosus Eukaryo. plasma 1 0 2.1 ± 1.4 53 ± 13 -3.5
2.2.06.02. Fatty acid-binding protein Sm14 1vyf Schistosoma mansoni Eukaryo. plasma 1 0 4.2 ± 1.4 48 ± 17 -2.8
2.2.06.02. Muscle fatty acid binding protein 1bwy Bos taurus Eukaryo. plasma 1 0 5.1 ± 1.2 67 ± 12 -5.9
2.2.06.02. Fatty acid-binding protein 1ftp Schistocerca gregaria Eukaryo. plasma 1 0 4.0 ± 1.6 51 ± 15 -4.7
2.2.06.02. Intestinal fatty acid binding protein 1icm Rattus norvegicus Eukaryo. plasma 1 0 3.3 ± 1.2 49 ± 15 -3.3
2.2.06.02. Cellular retinoic acid-binding protein 2 1cbs Homo sapiens Eukaryo. plasma 1 0 6.9 ± 1.3 36 ± 11 -4.9
2.2.06.02. Intestinal fatty acid binding protein 1kzw Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.2 56 ± 13 -3.1
2.2.06.02. Cellular retinoic acid-binding protein 1 1cbr Bos taurus Eukaryo. plasma 1 0 6.7 ± 1.1 40 ± 10 -3.2
2.2.06.02. Myelin p2 protein 1yiv Equus caballus Eukaryo. plasma 1 0 2.1 ± 1.0 46 ± 9 -2.5
2.2.06.02. Retinol-binding protein 4 1lpj Homo sapiens Secreted 1 0 2.3 ± 1.2 44 ± 15 -5.0
2.2.07.01. Polyisoprenoid-binding protein 1wub Thermus thermophilus Bact. gram-neg inner 1 0 3.7 ± 2.0 40 ± 11 -5.6
2.2.08.01. Osmotin-like protein 1aun Nicotiana tabacum Secreted 1 0 4.6 ± 1.1 89 ± 7 -4.6
2.2.08.01. Osmotin 1pcv Nicotiana tabacum Secreted 1 0 10.3 ± 1.0 73 ± 5 -2.6
2.2.09.01. Ganglioside GM2 activator, different conformation 1pub Homo sapiens Lysosome 1 0 5.2 ± 1.0 44 ± 4 -7.8
2.2.09.01. Ganglioside GM2 activator, apo-protein 2ag4 Homo sapiens Lysosome 1 0 4.2 ± 1.7 47 ± 10 -5.1
2.2.09.01. Ganglioside GM2 activator 1tjj Homo sapiens Lysosome 1 0 4.6 ± 1.4 55 ± 9 -9.3
2.2.09.01. Ganglioside GM2 activator 2agc Mus musculus Lysosome 1 0 4.5 ± 1.6 47 ± 14 -4.7
2.2.10.01. High potential iron protein 1hpi Ectothiorhodospira vacuolata Bact. gram-neg inner 1 0 3.8 ± 1.2 80 ± 11 -4.7
2.2.11.01. C2 domain of protein kinase C delta 1bdy Rattus norvegicus Eukaryo. plasma 1 0 1.2 ± 1.2 69 ± 10 -1.3
2.2.11.01. C2 domain of cytosolic phospholipase A2, group IVA 1rlw Homo sapiens Nuclear outer 1 0 5.3 ± 1.9 53 ± 18 -7.1
2.2.11.01. C2 domain of protein kinase C eta 2fk9 Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.8 55 ± 16 -2.5
2.2.11.01. C2 domain of protein kinase C delta 1yrk Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.5 56 ± 19 -1.4
2.2.11.01. E3 ubiquitin-protein ligase Itchy homolog 2nq3 Homo sapiens Eukaryo. plasma 1 0 3.4 ± 1.0 24 ± 6 -5.7
2.2.11.01. C2 domain of protein kinase C epsilon 1gmi Rattus rattus Eukaryo. plasma 1 0 2.0 ± 1.1 41 ± 10 -5.1
2.2.11.01. Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN 1d5r Homo sapiens Eukaryo. plasma 1 0 2.1 ± 1.9 81 ± 11 -2.6
2.2.11.02. C2A domain of synaptotagmin I (Calcium bound) 1byn Rattus norvegicus Eukaryo. plasma 1 0 3.7 ± 2.0 36 ± 20 -4.4
2.2.11.02. Synaptotagmin IV 1ugk Homo sapiens Eukaryo. plasma 1 0 2.4 ± 2.0 44 ± 20 -1.7
2.2.11.02. C2B domain of synaptotagmin I (Calcium bound) 1uov Rattus norvegicus Eukaryo. plasma 1 0 2.4 ± 1.8 32 ± 18 -4.3
2.2.11.02. C2 domain of protein kinase C beta 1a25 Rattus norvegicus Eukaryo. plasma 1 0 2.2 ± 1.4 38 ± 18 -2.2
2.2.11.02. C2 domain of rabphilin-3A 2chd Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 1.2 61 ± 9 -1.5
2.2.11.02. C2a-domain of Rab3 interacting molecule 2 (RIM2) 2bwq Rattus norvegicus Eukaryo. plasma 1 0 1.4 ± 2.0 39 ± 18 -1.5
2.2.11.02. C2A domain of synaptotagmin I (Calcium free) 3f00 Homo sapiens Eukaryo. plasma 1 0 1.1 ± 1.1 28 ± 8 -1.8
2.2.11.02. C2A domain of RIM2 2cjs Rattus norvegicus Eukaryo. plasma 1 0 3.9 ± 2.0 48 ± 16 -4.7
2.2.11.02. C2 domain of protein kinase C alpha, complex with phosphatidyl serine 1dsy Rattus norvegicus Eukaryo. plasma 1 0 1.5 ± 1.5 18 ± 9 -2.0
2.2.11.02. C2 domain of phosphatidylinositide 3-kinase C2 alpha 2b3r Mus musculus Eukaryo. plasma 2 0 1.8 ± 1.2 40 ± 17 -3.8
2.2.11.02. Synaptotagmin-1 C2A-C2B domains 2r83 Homo sapiens Eukaryo. plasma 1 0 3.1 ± 1.0 88 ± 11 -3.8
2.2.11.02. C2A domain of synaptotagmin I (Calcium free) 1rsy Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 1.0 26 ± 6 -3.3
2.2.11.02. Synaptotagmin III 1dqv Rattus norvegicus Eukaryo. plasma 1 0 2.4 ± 1.6 21 ± 19 -3.6
2.2.12.01. Exocyst complex component Sec5, complex with protein RalA from Human 1uad Rattus norvegicus Eukaryo. plasma 2 0 2.0 ± 1.3 41 ± 10 -2.2
2.2.12.02. Epididymal secretory protein E1 1nep Bos taurus Secreted 1 0 7.7 ± 1.0 70 ± 9 -5.3
2.2.12.03. Rho GDP-dissociation inhibitor 1 1qvy Homo sapiens Eukaryo. plasma 1 0 3.1 ± 1.4 53 ± 15 -5.1
2.2.12.03. Rho GDP-dissociation inhibitor 1, complex with cell division control protein 42 1doa Homo sapiens Eukaryo. plasma 2 0 1.7 ± 1.7 81 ± 12 -1.2
2.2.12.03. ADP-ribosylation factor 1 (ARF1) 2k5u Saccharomyces cerevisiae Golgi 1 0 2.8 ± 1.0 10 ± 10 -3.3
2.2.12.03. Rho GDP-dissociation inhibitor 2, complex with G-protein RAC2 1ds6 Homo sapiens Eukaryo. plasma 2 0 2.8 ± 1.2 77 ± 9 -5.1
2.2.12.03. ADP-ribosylation factor-like protein 2, complex with human PDEdelta 1ksg Mus musculus Eukaryo. plasma 1 0 9.6 ± 2.0 41 ± 8 -5.3
2.2.12.03. Rho GDP-dissociation inhibitor 1, complex with G-protein RAC2 1hh4 Homo sapiens Eukaryo. plasma 2 0 3.6 ± 0.7 88 ± 6 -3.5
2.2.13.01. ADP-ribosylation factor binding protein Gga3 domain 1p4u Homo sapiens Golgi 1 0 10.7 ± 2.0 34 ± 16 -6.9
2.2.14.01. C2 domains of factor Va 1sdd Bos taurus Eukaryo. plasma 2 0 3.3 ± 2.0 40 ± 4 -5.6
2.2.14.01. C2 domain of factor VIII 1d7p Homo sapiens Eukaryo. plasma 1 0 3.9 ± 1.8 15 ± 11 -8.1
2.2.14.01. C2 domain of factor V 1czs Homo sapiens Eukaryo. plasma 1 0 4.2 ± 2.0 19 ± 20 -3.0
2.2.15.01. Ectodomain of G-protein coupled receptor Mth 1fjr Drosophila melanogaster Eukaryo. plasma 1 0 2.4 ± 1.0 60 ± 4 -3.4
2.2.16.01. Lipoprotein lppX 2byo Mycobacterium tuberculosis Bact. gram-pos plas. 1 0 1.6 ± 1.0 80 ± 7 -2.1
2.2.17.01. Follicle-stimulating hormone, complex of alpha and beta chains 1fl7 Homo sapiens Eukaryo. plasma 4 0 2.1 ± 1.6 75 ± 6 -3.6
2.2.17.01. Follicle-stimulating hormone-receptor complex 1xwd Homo sapiens Eukaryo. plasma 3 0 3.1 ± 1.9 53 ± 10 -5.0
2.2.18.01. Major envelope glycoprotein E, ectodomain 1ok8 Dengue virus Viral 3 0 4.9 ± 1.5 0 ± 5 -9.9
2.2.18.01. Fusion glycoprotein E1 1rer Semiliki forest virus Viral 3 0 10.5 ± 1.0 61 ± 5 -5.1
2.2.18.01. Envelope glycoprotein 1urz Tick-borne encephalitis virus Viral 3 0 7.9 ± 1.0 7 ± 10 -12.2
2.2.19.01. Adsorption protein p2 1n7v Bacteriophage prd1 Viral 1 0 15.7 ± 1.0 82 ± 7 -11.9
2.2.20.01. SET binding factor 1 1v5u Mus musculus Eukaryo. plasma 1 0 4.6 ± 1.6 56 ± 18 -4.1
2.2.20.01. PH domain of Src-associated adaptor protein 2 homologue 1u5f Mus musculus Eukaryo. plasma 2 0 2.2 ± 1.1 90 ± 11 -4.7
2.2.20.01. Dynamin 1dyn Homo sapiens Eukaryo. plasma 2 0 4.3 ± 0.9 30 ± 5 -11.2
2.2.20.01. Triple functional domain protein 1nty Homo sapiens Eukaryo. plasma 1 0 3.1 ± 1.8 60 ± 19 -3.7
2.2.20.01. PH domain of 3-phosphoinositide-dependent protein kinase 1 1w1g Homo sapiens Eukaryo. plasma 1 0 3.6 ± 1.9 31 ± 15 -4.2
2.2.20.01. PH domain of Src-associated adaptor protein 2 1u5e Mus musculus Eukaryo. plasma 2 0 4.0 ± 3.0 20 ± 15 -3.3
2.2.20.01. Spectrin beta chain 1btn Mus musculus Eukaryo. plasma 1 0 0.5 ± 1.4 57 ± 17 -1.2
2.2.20.01. PH domain of phospholipase C delta 1 1mai Rattus norvegicus Eukaryo. plasma 1 0 2.5 ± 1.6 65 ± 19 -3.2
2.2.20.01. Pleckstrin 1pls Homo sapiens Eukaryo. plasma 1 0 3.2 ± 2.0 59 ± 20 -2.8
2.2.20.01. Phosphoinositol 3-phosphate binding protein 1 1upq Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.8 57 ± 20 -2.2
2.2.20.01. Son of sevenless homolog 1 (two domains) 1dbh Homo sapiens Eukaryo. plasma 1 0 3.2 ± 2.0 29 ± 12 -5.0
2.2.20.01. PH domain of TAPP2 1v5p Mus musculus Eukaryo. plasma 1 0 2.6 ± 1.4 85 ± 15 -2.7
2.2.20.01. Son of sevenless homolog 1 (SOS-1) 1xd4 Homo sapiens Eukaryo. plasma 1 0 3.2 ± 3.0 68 ± 13 -4.6
2.2.20.01. Cytohesin-3 (Grp1) 1fhx Mus musculus Eukaryo. plasma 1 0 3.1 ± 0.8 82 ± 11 -3.2
2.2.20.01. T-lymphoma invasion and metastasis-inducing protein 1, with G-protein RAC2 1foe Mus musculus Eukaryo. plasma 2 0 4.8 ± 1.8 46 ± 10 -6.2
2.2.20.01. PH domain of GPCR kinase 2 2bcj Bos taurus Eukaryo. plasma 3 0 3.3 ± 2.0 83 ± 2 -5.5
2.2.20.01. PH domain containing retinal protein 1 2d9v Mus musculus Eukaryo. plasma 1 0 3.0 ± 1.7 57 ± 11 -2.8
2.2.20.01. Dual adaptor of phosphotyrosine and 3-phosphoinositides 1fao Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.7 54 ± 18 -3.9
2.2.20.01. PH domain of tyrosine-protein kinase BTK 1bwn Homo sapiens Eukaryo. plasma 2 0 3.0 ± 0.5 89 ± 10 -2.0
2.2.20.01. PH domain of docking protein 2 2d9w Homo sapiens Eukaryo. plasma 1 0 1.2 ± 1.2 19 ± 15 -1.3
2.2.20.01. PH domain of TAPP1 1eaz Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.7 77 ± 18 -2.1
2.2.20.01. PH domain of oxysterol binding protein-related protein 11 2d9x Homo sapiens Eukaryo. plasma 1 0 1.8 ± 1.8 51 ± 17 -2.3
2.2.20.01. Rac-alpha serine/threonine kinase 1unq Homo sapiens Eukaryo. plasma 1 0 1.6 ± 1.5 30 ± 20 -2.0
2.2.20.01. PH domain of muscle M-line assembly protein unc-89 1fho Caenorhabditis elegans Eukaryo. plasma 1 0 2.0 ± 1.7 12 ± 19 -2.3
2.2.20.01. Rac-beta serine/threonine protein kinase 1p6s Homo sapiens Eukaryo. plasma 1 0 4.4 ± 1.1 88 ± 15 -2.3
2.2.20.01. PH domain of Src-associated adaptor 55 protein 1u5d Homo sapiens Eukaryo. plasma 2 0 2.0 ± 1.7 12 ± 19 -2.3
2.2.20.02. Disabled homolog 1 1nu2 Mus musculus Eukaryo. plasma 1 0 0.5 ± 2.0 49 ± 20 -0.6
2.2.20.03. Radixin 1gc6 Mus musculus Eukaryo. plasma 1 0 1.1 ± 1.4 26 ± 11 -1.7
2.2.21.01. Hisactophilin-1 1hce Dictyostelium discoideum Eukaryo. plasma 1 0 1.9 ± 1.9 85 ± 20 -1.2
2.2.22.01. Hydrophobin II 1r2m Hypocrea jecorina Secreted 1 0 3.3 ± 0.9 23 ± 10 -7.8
2.2.22.01. Hydrophobin I 2gvm Hypocrea jecorina Secreted 1 0 5.5 ± 0.3 24 ± 9 -11.6
2.2.24.01. Vitelline membrane outer protein-I 1vmo Gallus gallus Secreted 1 0 3.0 ± 1.4 56 ± 10 -3.4
2.2.26.01. FYVE domain of protein 19 1wfk Mus musculus Vesicle 1 0 4.3 ± 1.9 27 ± 19 -4.3
2.2.26.01. Early endosome antigen 1 (EEA1), monomer 1hyi Homo sapiens Endosome 1 0 2.5 ± 1.9 26 ± 20 -2.9
2.2.26.01. Early endosome antigen 1 (EEA1), model of dimer with lipids 1joc Homo sapiens Endosome 2 0 0.0 ± 1.0 8 ± 18 -2.9
2.2.26.01. LM-5 FYVE domain 1z2q Leishmania major Endosome 1 0 2.1 ± 1.7 29 ± 14 -3.4
2.2.26.01. FYVE domain of Vps27 protein 1vfy Saccharomyces cerevisiae Vacuole 1 0 2.9 ± 1.5 26 ± 19 -4.0
2.2.26.01. FYVE domain of protein 27 1x4u Homo sapiens Vesicle 1 0 3.1 ± 1.5 50 ± 13 -4.4
2.2.27.01. C1 domain of protein kinase C delta 1ptr Mus musculus Eukaryo. plasma 1 0 6.8 ± 1.7 10 ± 19 -5.7
2.2.27.01. Kinase supressor of Ras, Ksr 1kbf Mus musculus Eukaryo. plasma 1 0 2.4 ± 1.7 54 ± 11 -4.0
2.2.27.01. RAF-1 proto-oncogene serine/threonine-protein kinase 1faq Homo sapiens Eukaryo. plasma 1 0 5.5 ± 1.0 26 ± 14 -8.1
2.2.27.01. Beta-chimaerin 1xa6 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.7 79 ± 18 -2.3
2.2.27.01. Protein kinase C-gamma 1tbn Rattus rattus Eukaryo. plasma 1 0 7.5 ± 1.0 46 ± 7 -2.3
2.2.27.01. C1 domain of unc-13 homolog A 1y8f Rattus norvegicus Eukaryo. plasma 1 0 1.9 ± 1.1 47 ± 19 -2.1
2.2.27.01. Diacylglycerol kinase delta 1r79 Homo sapiens Eukaryo. plasma 1 0 3.3 ± 2.0 46 ± 20 -5.2
2.2.27.01. C1 domanin of SH3 and cysteine-rich domain-containing protein 3 2db6 Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.3 9 ± 7 -3.7
2.2.28.01. Gurmarin 1c4e Gymnema sylvestre Secreted 1 0 4.8 ± 1.8 25 ± 20 -4.0
2.2.29.01. Agouti-related protein 1mr0 Homo sapiens Secreted 1 0 3.8 ± 1.5 16 ± 20 -4.2
2.2.30.01. Elafin, complex with elastase from Pig 1fle Homo sapiens Secreted 2 0 4.4 ± 1.4 50 ± 8 -5.7
2.2.30.01. Nawaprin 1udk Naja nigricollis Secreted 1 0 7.4 ± 1.4 77 ± 19 -8.8
2.2.31.01. Collagen-binding type II domain of seminal plasma protein PDC-109 1h8p Bos taurus Secreted 2 0 9.2 ± 1.3 88 ± 8 -12.3
2.2.32.01. Equinatoxin II 1iaz Actinia equina Secreted 1 0 3.1 ± 1.8 38 ± 15 -2.2
2.2.32.01. Sticholysin II 1gwy Stoichactis helianthus Secreted 1 0 4.3 ± 1.8 31 ± 17 -3.6
2.2.33.01. Soybean trypsin inhibitor, complex with trypsin 1avw Glycine max Eukaryo. plasma 2 0 7.3 ± 1.9 66 ± 12 -5.8
2.2.33.02. Botulinum neurotoxin B 1epw Clostridium botulinum Secreted 1 0 3.3 ± 2.0 26 ± 8 -4.5
2.2.34.01. Omega conotoxin SO3 1fyg Conus striatus Secreted 1 0 3.1 ± 1.2 69 ± 15 -3.3
2.2.34.01. Delta conotoxin EVIA 1g1z Conus ermineus Secreted 1 0 6.3 ± 1.6 34 ± 16 -11.3
2.2.34.01. Omega conotoxin TxVII 1f3k Conus textile Secreted 1 0 4.9 ± 1.3 71 ± 18 -4.9
2.2.34.01. Delta conotoxin TxVIA 1fu3 Conus textile Secreted 1 0 6.4 ± 1.3 24 ± 18 -9.7
2.2.34.01. Mu-O conotoxin MrVIB 1rmk Conus marmoreus Secreted 1 0 18.3 ± 1.2 22 ± 19 -16.9
2.2.34.02. omega-Agatoxin 1agg Agelenopsis aperta Secreted 1 0 2.6 ± 1.4 49 ± 13 -4.5
2.2.34.02. ACTX-HI:OB4219 1kqi Hadronyche infensa Secreted 1 0 9.8 ± 1.3 57 ± 19 -6.6
2.2.34.02. Atracotoxin-hvI 1vtx Hadronyche versuta Secreted 1 0 4.4 ± 1.6 74 ± 19 -6.7
2.2.34.02. Huwentoxin-4 1mb6 Haplopelma schmidti (Chinese bird spider) Secreted 1 0 2.5 ± 1.1 77 ± 14 -2.7
2.2.34.02. Robustoxin 1qdp Atrax robustus Secreted 1 0 2.9 ± 1.4 82 ± 18 -4.3
2.2.34.02. Jingzhaotoxin-11 2a2v Chilobrachys guangxiensis (Chinese earth tiger tarantula) Secreted 1 0 2.2 ± 1.9 90 ± 19 -2.6
2.2.34.02. Huwentoxin-1 1qk6 Haplopelma schmidti (Chinese bird spider) Secreted 1 0 2.9 ± 1.7 85 ± 15 -4.1
2.2.34.02. Omega-agatoxin-4A 1oav Agelenopsis aperta Secreted 1 0 7.4 ± 1.3 72 ± 14 -4.8
2.2.34.02. Phrixotoxin 1 1v7f Paraphysa scrofa Secreted 1 0 4.3 ± 0.9 88 ± 13 -5.7
2.2.34.02. Hanatoxin 1 1d1h Grammostola rosea (Chilean rose tarantula) Secreted 1 0 3.9 ± 1.3 70 ± 15 -2.5
2.2.34.02. Voltage sensor toxin VSTx1 1s6x Grammostola rosea (Chilean rose tarantula) Secreted 1 0 4.4 ± 1.1 89 ± 18 -5.2
2.2.34.02. Psalmotoxin-1 1lmm Psalmopoeus cambridgei (Trinidad chevron tarantula) Secreted 1 0 2.8 ± 1.4 81 ± 15 -1.3
2.2.34.03. Toxin Ado1 1lmr Agriosphodrus dohrni Secreted 1 0 3.5 ± 1.8 53 ± 20 -3.7
2.2.34.04. Leginsulin 1ju8 Glycine max Secreted 1 0 14.8 ± 1.6 23 ± 18 -13.2
2.2.34.04. Albumin 1 subunit B (Pab1) 1p8b Pisum sativum Secreted 1 0 11.8 ± 0.9 27 ± 11 -9.4
2.2.35.01. Perfringolysin 1pfo Clostridium perfringens Secreted 1 0 3.4 ± 8.0 42 ± 5 -5.5
2.2.36.01. Circulin A 1bh4 Chassalia parviflora Secreted 1 0 6.3 ± 1.1 67 ± 15 -8.7
2.2.36.02. Kalata B2, segment 71-98 (repeat 1) 1pt4 Oldenlandia affinis Secreted 1 0 4.5 ± 1.0 84 ± 14 -9.8
2.2.36.02. Kalata B1, segment 93-120 1nb1 Oldenlandia affinis Secreted 1 0 5.2 ± 1.5 89 ± 20 -5.4
2.2.36.02. Kalata B1, segment 89-109 1kal Oldenlandia affinis Secreted 1 0 5.4 ± 1.8 89 ± 19 -5.8
2.2.36.02. Kalata B1, segment 95-112 1orx Oldenlandia affinis Secreted 1 0 4.8 ± 1.9 78 ± 20 -5.6
2.2.36.03. Cycloviolacin O1 1df6 Viola odorata Secreted 1 0 3.6 ± 1.7 64 ± 15 -4.8
2.2.36.03. Cycloviolacin O1 1vb8 Viola hederacea Secreted 1 0 9.8 ± 1.6 73 ± 14 -12.7
2.2.36.04. Palicourein 1r1f Palicourea condensata Secreted 1 0 3.4 ± 1.9 40 ± 18 -3.8
2.2.37.02. Defensin ARD1 1ozz Archaeoprepona demophon Secreted 1 0 4.8 ± 1.2 17 ± 18 -6.8
2.2.37.02. Sapecin 1l4v Sarcophaga peregrina Secreted 1 0 4.4 ± 1.4 83 ± 17 -6.6
2.2.37.02. Drosomycin 1myn Drosophila melanogaster Secreted 1 0 4.5 ± 1.4 13 ± 19 -6.8
2.2.37.03. Charybdotoxin 2crd Leiurus quinquestriatus hebraeus Secreted 1 0 1.2 ± 1.2 87 ± 18 -1.6
2.2.37.03. Toxin I5a 1sis Buthus eupeus Secreted 1 0 3.7 ± 1.5 65 ± 20 -3.4
2.2.37.04. Defensin 1 1jkz Pisum sativum Secreted 1 0 3.3 ± 1.3 10 ± 20 -4.1
2.2.37.04. Antifungal protein 1 1ayj Raphanus sativus Secreted 1 0 11.3 ± 1.9 27 ± 19 -8.9
2.2.38.01. Colicin E3 1jch Escherichia coli Secreted 4 0 2.7 ± 0.5 90 ± 4 -9.0
2.2.39.01. Cardiotoxin III (cytotoxin 3) 1h0j Naja naja atra Secreted 1 0 6.5 ± 0.8 54 ± 11 -13.1
2.2.39.01. Toxin B 1txa Ophiophagus hannah Secreted 1 0 3.4 ± 1.7 50 ± 19 -4.1
2.2.39.01. Cardiotoxin-A5 1kxi Naja naja atra Secreted 1 0 7.2 ± 1.2 65 ± 13 -11.2
2.2.39.01. Cytotoxin 1 ( Cardiotoxin gamma) 1tgx Naja mossambica pallida Secreted 1 0 6.8 ± 0.6 55 ± 12 -12.4
2.2.39.01. Cardiotoxin-A1 (cytotoxin 1) 2cdx Naja naja atra Secreted 1 0 3.5 ± 1.0 84 ± 8 -8.0
2.2.39.01. Cardiotoxin V4II 1cdt Naja mossambica mossambica Secreted 2 0 4.1 ± 1.2 73 ± 13 -6.8
2.2.39.01. Cytotoxin-1 1rl5 Naja naja oxiana Secreted 1 0 10.0 ± 0.1 46 ± 4 -7.3
2.2.39.01. Cardiotoxin VI 1ug4 Naja naja atra Secreted 1 0 7.3 ± 0.6 55 ± 7 -17.6
2.2.39.01. alpha-Cobratoxin 1ctx Naja naja siamensis Secreted 1 0 3.0 ± 1.0 24 ± 13 -3.2
2.2.39.01. Bungarotoxin 1hc9 Bungarus multicinctus Secreted 1 0 3.4 ± 2.0 55 ± 17 -3.2
2.2.39.01. Cardiotoxin II (cytotoxin II) 1ffj Naja naja oxiana Secreted 1 0 8.7 ± 0.7 46 ± 12 -18.1
2.2.39.02. Dendroaspin (mambin) 1drs Dendroaspis jamesoni kaimosae Secreted 1 0 2.8 ± 1.6 81 ± 17 -5.7
2.2.40.01. Neurotoxin III 1ans Anemonia sulcata Secreted 1 0 2.4 ± 1.8 43 ± 20 -3.3
2.2.41.01. Spheniscin-2 1ut3 Aptenodytes patagonicus Secreted 1 0 3.2 ± 1.2 28 ± 16 -4.0
2.2.41.01. Alpha-defensin cryptdin-4 1tv0 Mus musculus Secreted 1 0 3.2 ± 1.8 44 ± 16 -3.4
2.2.41.01. Alpha-defensin corticostatin-related peptide RK-1 1ews Oryctolagus cuniculus Secreted 1 0 4.3 ± 1.9 19 ± 19 -3.6
2.2.41.01. Alpha-defensin 4 1zmm Homo sapiens Secreted 1 0 6.9 ± 1.0 47 ± 6 -4.7
2.2.41.01. Alpha-defensin 5 1zmp Homo sapiens Secreted 1 0 2.3 ± 1.0 74 ± 10 -0.4
2.2.41.01. Beta-defensin 1 1ijv Homo sapiens Secreted 1 0 4.6 ± 1.6 36 ± 18 -5.3
2.2.41.01. Alpha-defensin 6 1zmq Homo sapiens Secreted 1 0 6.5 ± 1.0 54 ± 16 -2.1
2.2.41.01. Beta-defensin 3 1kj6 Homo sapiens Secreted 1 0 3.4 ± 0.8 18 ± 17 -4.8
2.2.41.01. Beta-defensin 7 1e4t Mus musculus Secreted 1 0 3.7 ± 1.3 9 ± 15 -5.1
2.2.41.01. Neutrophil defensin 1 1dfn Homo sapiens Secreted 2 0 2.5 ± 1.3 75 ± 19 -2.9
2.2.41.01. Beta-defensin 8 1e4r Mus musculus Secreted 1 0 3.2 ± 1.3 8 ± 19 -3.7
2.2.41.01. Alpha-defensin 2 1zmi Homo sapiens Secreted 1 0 2.9 ± 1.5 66 ± 19 -3.0
2.2.41.01. Beta-defensin 12 1bnb Bos taurus Secreted 1 0 7.0 ± 1.2 88 ± 10 -16.0
2.2.41.01. Beta-defensin 2 1fd3 Homo sapiens Secreted 1 0 6.8 ± 0.3 68 ± 5 -12.3
2.2.41.02. Toxin APETx1 1wqk Anthopleura elegantissima (Sea anemone) Secreted 1 0 3.2 ± 1.1 45 ± 15 -5.6
2.2.41.02. Toxin APETx2 1wxn Anthopleura elegantissima (Sea anemone) Secreted 1 0 5.2 ± 1.4 39 ± 16 -2.7
2.2.41.02. Antihypertensive protein BDS-1 1bds Anemonia sulcata Secreted 1 0 6.6 ± 1.9 65 ± 18 -11.9
2.2.41.02. Sea anemone neurotoxin-1 1shi Stichodactyla helianthus Secreted 1 0 4.9 ± 1.9 80 ± 20 -5.9
2.2.41.02. Sea anemone toxin IA 1atx Anemonia sulcata Secreted 1 0 2.9 ± 1.6 69 ± 17 -5.6
2.2.41.02. Anthopleurin-A 1ahl Anthopleura xanthogrammica Secreted 1 0 11.5 ± 1.4 76 ± 17 -8.7
2.2.41.02. Anthopleurin-B 1apf Anthopleura xanthogrammica Secreted 1 0 6.5 ± 1.5 83 ± 14 -6.4
2.2.42.01. Matrix protein 2vqp Human respiratory syncytial virus Eukaryo. plasma 1 0 2.8 ± 1.0 87 ± 8 -3.8
2.2.43.01. Protein OxaA, periplasmic domain 3blc Escherichia coli Bact. gram-neg inner 1 0 8.6 ± 1.0 36 ± 13 -2.5