PDB ID or protein name

Alpha + Beta monotopic/peripheral superfamilies

2.4.01. FAD-linked reductases, C-terminal domain (1 family)
2.4.02. NTF2-like (1 family)
2.4.03. Transcriptional factor tubby, C-terminal domain (1 family)
2.4.04. DNase I-like (2 families)
2.4.05. Sterol carrier protein (1 family)
2.4.06. Bet v1-like (2 families)
2.4.07. PX domain (1 family)
2.4.08. MHC antigen-recognition domain (1 family)
2.4.09. SNARE-like (3 families)
2.4.10. PreATP-grasp domain (1 family)
2.4.11. Crambin-like (1 family) 1.C.44 (TCDB)
2.4.12. Leucocin-like bacteriocin (1 family) 1.C.24 (TCDB)
2.4.13. OSBP-related proteins (1 family)

Alpha + Beta monotopic/peripheral (57 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.2.25.01. STAT3b 1bg1 Mus musculus Nuclear inner 2 0 1.7 ± 8.0 90 ± 10 -6.3
2.2.37.01. LQH III alpha-like toxin 1fh3 Leiurus quinquestriatus hebraeus Secreted 1 0 7.3 ± 1.5 75 ± 9 -4.7
2.2.37.01. Neurotoxin 3 2sn3 Centruroides sculpturatus ewing Secreted 1 0 6.4 ± 1.5 81 ± 11 -5.5
2.2.37.01. Neurotoxin 2 1jza Centruroides sculpturatus ewing Secreted 1 0 4.1 ± 1.4 69 ± 18 -6.1
2.2.37.01. Toxin 2 1cn2 Centruroides noxius hoffmann Secreted 1 0 2.6 ± 1.1 81 ± 19 -4.3
2.2.37.01. Alpha-like neurotoxin BmK-I 1djt Buthus martensii Secreted 2 0 3.6 ± 0.8 86 ± 10 -5.3
2.2.37.01. Neurotoxin 1dq7 Buthus tamulus Secreted 1 0 5.3 ± 1.5 76 ± 15 -7.4
2.2.37.01. Toxin VII 1npi Tityus serrulatus Secreted 1 0 4.1 ± 1.6 79 ± 18 -5.3
2.2.37.01. Tx10 alpha-like toxin 1kv0 Buthus martensii Secreted 1 0 5.0 ± 1.0 74 ± 18 -2.3
2.2.37.01. Beta-insect excitatory toxin BmKIT1 1wwn Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 46.0 ± 10.0 3 ± 2 -3.9
2.3.05.04. Sulfide:quinone oxidoreductase 3h28 Aquifex aeolicus Bact. gram-neg inner 3 0 2.3 ± 0.1 90 ± 1 -4.7
2.4.01.01. PX domain of vacuolar morphogenesis protein VAM7 1kmd Saccharomyces cerevisiae Vacuole 1 0 3.5 ± 1.0 76 ± 8 -6.5
2.4.01.01. Cholesterol oxidase 1coy Brevibacterium sterolicum Bact. gram-pos plas. 1 0 5.3 ± 1.8 34 ± 14 -4.1
2.4.01.01. PX domain of NADH oxidase (p40phox), ligand-bound 1h6h Homo sapiens Endosome 1 0 3.2 ± 1.6 58 ± 18 -7.8
2.4.01.01. PX domain of NADH oxidase (p47phox), ligand-bound 1o7k Homo sapiens Endosome 1 0 1.5 ± 1.0 86 ± 3 -4.4
2.4.01.01. Cholesterol oxidase 1b4v Streptomyces sp. Bact. gram-pos plas. 1 0 5.7 ± 1.3 38 ± 18 -7.1
2.4.01.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens Endosome 1 0 1.4 ± 2.0 46 ± 8 -1.9
2.4.01.01. PX domain of sorting nexin GRD19, ligand-bound 1ocu Saccharomyces cerevisiae Endosome 2 0 1.9 ± 0.7 89 ± 10 -3.5
2.4.01.01. PX domain of sorting nexin GRD19, ligand-free 1ocs Saccharomyces cerevisiae Endosome 1 0 3.0 ± 1.2 86 ± 10 -4.8
2.4.01.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Homo sapiens Golgi 1 0 3.9 ± 1.1 64 ± 17 -3.6
2.4.01.01. PX domain of serine/threonine-protein kinase Sgk3 1xte Homo sapiens Endosome 1 0 2.3 ± 2.0 82 ± 13 -1.1
2.4.01.01. PX domain of C2alpha-PI3 kinase 2ar5 Homo sapiens Eukaryo. plasma 1 0 2.6 ± 1.0 70 ± 17 -2.6
2.4.01.01. PX domain of sorting nexin-17 (SNX17) 3fog Homo sapiens Endosome 1 0 3.4 ± 2.0 80 ± 13 -3.9
2.4.02.01. Epoxide Hydrolase 2bng Mycobacterium bovis Bact. gram-pos plas. 2 0 8.1 ± 0.5 87 ± 5 -26.9
2.4.03.01. Tubby protein, ligand-bound 1i7e Mus musculus Eukaryo. plasma 1 0 2.6 ± 1.5 78 ± 13 -3.6
2.4.03.01. Tubby protein, ligand-free 1c8z Mus musculus Eukaryo. plasma 1 0 6.2 ± 1.0 87 ± 12 -4.7
2.4.04.01. Sphingomyelinase C 1zwx Listeria ivanovii Secreted 1 0 6.0 ± 1.6 52 ± 13 -6.2
2.4.04.01. Sphingomyelinase C 2ddt Bacillus cereus Secreted 1 0 3.7 ± 2.0 45 ± 12 -2.7
2.4.04.02. Sphingomyelinase D 1 1xx1 Loxosceles laeta Secreted 1 0 9.3 ± 1.0 71 ± 4 -12.0
2.4.05.01. Sterol carrier protein 2 2cx7 Thermus thermophilus Bact. gram-neg inner 1 0 7.0 ± 0.9 67 ± 14 -7.0
2.4.05.01. Sterol carrier protein 2 1c44 Oryctolagus cuniculus Eukaryo. plasma 1 0 4.0 ± 1.3 80 ± 18 -3.2
2.4.05.01. Complex of Pex5p with sterol carrier protein 2 2c0l Homo sapiens Eukaryo. plasma 2 0 5.6 ± 1.6 86 ± 11 -7.1
2.4.05.01. Sterol carrier protein 2 like domain of multifunctional enzyme type 2 1ikt Homo sapiens Peroxisome 1 0 1.7 ± 1.2 84 ± 15 -2.1
2.4.06.01. STAR-related lipid transfer protein 11, complex with C18 ceramide 2e3q Homo sapiens Golgi 1 0 4.0 ± 1.6 52 ± 18 -1.4
2.4.06.01. Cholesterol-regulated Start protein 4 (StarD4) 1jss Mus musculus Eukaryo. plasma 1 0 2.6 ± 1.2 53 ± 12 -4.9
2.4.06.01. STAR-related lipid transfer protein 11, apoprotein (open state) 2e3m Homo sapiens Golgi 1 0 3.2 ± 1.3 46 ± 9 -5.5
2.4.06.01. Lipid transport protein Mln64 (StARD3) 1em2 Homo sapiens Endosome 1 0 4.7 ± 1.3 89 ± 10 -2.9
2.4.06.01. Phosphatidylcholine transfer protein 1ln1 Homo sapiens Eukaryo. plasma 1 0 3.5 ± 1.9 44 ± 18 -3.3
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1uw5 Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.4 16 ± 9 -3.7
2.4.06.02. Phosphatidylinositol transfer protein beta isoform 2a1l Rattus norvegicus Eukaryo. plasma 1 0 2.4 ± 2.0 41 ± 20 -2.8
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1kcm Mus musculus Eukaryo. plasma 1 0 5.5 ± 1.9 56 ± 4 -8.7
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1t27 Rattus norvegicus Eukaryo. plasma 1 0 3.8 ± 2.0 38 ± 19 -2.2
2.4.08.01. T-cell surface glycoprotein CD1d antigen, bound to galactosyl ceramide 1z5l Mus musculus Secreted 2 0 2.4 ± 1.2 26 ± 16 -3.0
2.4.08.01. T-cell surface glycoprotein CD1d antigen, bound to phosphatidylcholine 1zhn Mus musculus Secreted 2 0 2.3 ± 1.0 25 ± 8 -3.6
2.4.09.01. Synaptobrevin homolog 1 1iou Saccharomyces cerevisiae Eukaryo. plasma 1 0 5.1 ± 2.0 40 ± 20 -4.8
2.4.09.02. Signal recognition particle receptor 1nrj Saccharomyces cerevisiae Endoplasm. reticulum 2 0 3.5 ± 0.1 80 ± 8 -4.9
2.4.09.03. Trafficking protein particle complex protein 2 (Sedlin) 1h3q Mus musculus Nuclear outer 1 0 3.3 ± 1.5 0 ± 12 -4.3
2.4.11.01. Alpha-1-purothionin 2plh Triticum aestivum Secreted 1 0 4.3 ± 1.0 48 ± 9 -3.5
2.4.11.01. Viscotoxin A3 1okh Viscum album Secreted 1 0 5.8 ± 1.0 17 ± 11 -4.0
2.4.11.01. Viscotoxin B 1jmp Viscum album Secreted 1 0 0.6 ± 1.0 50 ± 15 -1.4
2.4.11.01. Crambin 1ejg Crambe abyssinica Secreted 1 0 3.2 ± 1.2 82 ± 13 -7.0
2.4.11.01. Viscotoxin A2 1jmn Viscum album Secreted 1 0 0.7 ± 2.0 50 ± 11 -0.9
2.4.11.01. beta-Purothionin 1bhp Triticum aestivum Secreted 1 0 2.8 ± 1.6 52 ± 18 -3.5
2.4.11.01. Hellethionin D 1nbl Helleborus purpurascens Secreted 1 0 2.7 ± 1.2 43 ± 13 -5.1
2.4.12.01. Sakacin P 1ohm Lactobacillus sake Secreted 1 0 2.3 ± 1.6 87 ± 15 -2.2
2.4.12.01. Leucocin A 1cw6 Leuconostoc gelidum Secreted 1 0 4.0 ± 1.2 88 ± 17 -5.6
2.4.13.01. Oxysterol-binding protein 1zi7 Saccharomyces cerevisiae Eukaryo. plasma 1 0 3.0 ± 1.0 79 ± 9 -5.9