PDB ID or protein name

Alpha + Beta monotopic/peripheral superfamilies

2.4.01. FAD-linked reductases (1 family)
2.4.02. NTF2-like (2 families) CL0051 (Pfam)
2.4.03. Transcriptional factor tubby (1 family) PF01167 (Pfam)
2.4.04. DNase I-like (2 families)
2.4.05. Sterol carrier protein (2 families) CL0311 (Pfam)
2.4.06. Bet v1-like (4 families) CL0209 (Pfam)
2.4.07. PX domain (1 family) PF00787 (Pfam)
2.4.08. Ribonuclease-like (1 family)
2.4.09. Protein kinase superfamily (1 family) CL0016 (Pfam)
2.4.10. PreATP-grasp domain (1 family)
2.4.11. Plant thionin (1 family) 1.C.44 (TCDB) PF00321 (Pfam)
2.4.12. Liver-expressed antimicrobial peptide (1 family) PF07359 (Pfam)
2.4.13. OSBP-related proteins (1 family) PF01237 (Pfam)
2.4.15. Negative factor (Nef) protein (1 family) PF00469 (Pfam)
2.4.16. Scorpion toxin-like knottin (11 families) CL0054 (Pfam)
2.4.17. Apolipoprotein of LDL particles (1 family) PF01347 (Pfam)
2.4.18. NTN hydrolase superfamily (1 family) CL0052 (Pfam)
2.4.19. GlnB-like superfamily (1 family) CL0089 (Pfam)
2.4.20. Peptidase clan CA (4 families) CL0125 (Pfam)
2.4.21. Peptidase MD (2 families) CL0170 (Pfam)
2.4.23. Heme NO and oxygen binding like (1 family) CL0210 (Pfam)
2.4.24. Enolase like TIM barrel (1 family) CL0256 (Pfam)
2.4.25. N-acetyltransferase like (1 family) CL0257 (Pfam)
2.4.26. HIT superfamily (1 family) CL0265 (Pfam)
2.4.27. AIG2/ChaC-like superfamily (1 family) CL0278 (Pfam)
2.4.28. DAP epimerase superfamily (1 family) CL0288 (Pfam)
2.4.29. Superantigen toxins (1 family) CL0386 (Pfam)
2.4.30. TRAF domain-like superfamily (1 family) CL0389 (Pfam)
2.4.31. Fibrinogen (1 family) CL0422 (Pfam)
2.4.32. Acid phosphatase/Vanadium-dependent haloperoxidase (1 family) CL0525 (Pfam)
2.4.33. PGBD superfamily (2 families) CL0244 (Pfam)
2.4.34. Cysteine-rich secretory protein (CRISP) family (1 family) PF00188 (Pfam)
2.4.35. Catalase (1 family) PF00199 (Pfam)
2.4.36. Transforming growth factor (TGF)-beta (1 family) PF00688 (Pfam)
2.4.37. Acylphosphatase (1 family) PF00708 (Pfam)
2.4.38. N-acetylmuramoyl-L-alanine amidase (1 family) PF01510 (Pfam)
2.4.39. Antirestriction protein (1 family) PF03230 (Pfam)
2.4.40. IpaB/EvcA family (1 family) PF03278 (Pfam)
2.4.41. Hepatitis C virus non-structural protein NS2 (1 family) PF01538 (Pfam)
2.4.42. Bactericidal permeability increasing protein family (1 family) 1.C.40 (TCDB) PF01273 (Pfam)
2.4.45. Formylglycine-generating sulfatase enzyme (1 family) PF03781 (Pfam)
2.4.46. Cell envelope-related transcriptional attenuator domain (1 family) PF03816 (Pfam)
2.4.47. Neutral/alkaline non-lysosomal ceramidase (1 family) PF04734 (Pfam)
2.4.48. PPPDE putative peptidase domain (1 family) PF05903 (Pfam)
2.4.49. Inositol-pentakisphosphate 2-kinase (1 family) PF06090 (Pfam)
2.4.50. Vesiculovirus matrix protein (1 family) PF06326 (Pfam)
2.4.51. Heme-binding protein A (1 family) PF06438 (Pfam)
2.4.52. Spondin (1 family) PF06468 (Pfam)
2.4.53. Resistin (1 family) PF06954 (Pfam)
2.4.54. PilZ domain (1 family) PF07238 (Pfam)
See list of these PDB codes

Alpha + Beta monotopic/peripheral (185 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.4.01.01. Cholesterol oxidase 1coy Brevibacterium sterolicum Bact. Gram-pos plas. 1 0 4.4 ± 1.1 43 ± 10 -6.8
2.4.01.01. Cholesterol oxidase 1b4v Streptomyces sp. Bact. Gram-pos plas. 1 0 5.4 ± 0.6 39 ± 4 -8.4
2.4.02.01. Epoxide Hydrolase 2bng Mycobacterium bovis Bact. Gram-pos plas. 2 0 8.2 ± 0.6 88 ± 4 -24.0
2.4.02.02. Steroid Delta-isomerase 1cqs Pseudomonas putida Bact. Gram-neg inner 1 0 2.4 ± 1.7 78 ± 14 -2.8
2.4.02.02. Steroid Delta-isomerase 1vzz Pseudomonas putida Bact. Gram-neg inner 2 0 2.2 ± 2.6 72 ± 8 -4.4
2.4.03.01. Tubby protein, ligand-bound 1i7e Mus musculus Eukaryo. plasma 1 0 3.8 ± 1.9 75 ± 13 -4.7
2.4.03.01. Tubby protein homolog 1s31 Homo sapiens Eukaryo. plasma 1 0 6.8 ± 1.0 71 ± 2 -7.6
2.4.03.01. Tubby protein, ligand-free 1c8z Mus musculus Eukaryo. plasma 1 0 2.8 ± 0.9 89 ± 13 -5.8
2.4.04.01. Sphingomyelinase C 1zwx Listeria ivanovii Secreted 1 0 6.2 ± 0.5 55 ± 1 -10.1
2.4.04.01. Sphingomyelinase C 2ddt Bacillus cereus Secreted 1 0 4.1 ± 1.1 59 ± 8 -7.6
2.4.04.01. Beta-hemolysin 3i48 Staphylococcus aureus Secreted 1 0 2.8 ± 0.8 57 ± 5 -5.1
2.4.04.01. Type II inositol-1,4,5-trisphosphate 5-phosphatase 3n9v Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.4 63 ± 6 -6.0
2.4.04.02. Sphingomyelinase D 1 1xx1 Loxosceles laeta Secreted 1 0 8.1 ± 1.0 70 ± 8 -10.6
2.4.05.01. Uncharacterized protein 3cnu Archaeoglobus fulgidus Archaebac. 1 0 7.6 ± 1.7 69 ± 20 -7.0
2.4.05.01. Sterol carrier protein 2 1pz4 Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.8 ± 5.0 37 ± 49 -1.3
2.4.05.01. Sterol carrier protein 2 like domain of multifunctional enzyme type 2 1ikt Homo sapiens Peroxisome 1 0 3.5 ± 1.2 75 ± 17 -4.0
2.4.05.01. Sterol carrier protein 2 1c44 Oryctolagus cuniculus Eukaryo. plasma 1 0 3.7 ± 1.2 74 ± 17 -4.8
2.4.05.01. Sterol carrier protein 2 2cx7 Thermus thermophilus Bact. Gram-neg inner 1 0 4.7 ± 1.3 73 ± 13 -6.9
2.4.05.01. Uncharacterized protein 3bkr Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.4 ± 6.2 50 ± 73 -1.2
2.4.05.01. Sterol carrier protein 2-like 2 2qzt Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 1.0 ± 2.0 45 ± 12 -3.0
2.4.05.02. SDS hydrolase SdsA1 2cfu Pseudomonas aeruginosa Secreted 1 0 6.0 ± 2.5 70 ± 4 -7.0
2.4.06.01. Acyl-coenzyme A thioesterase 11 3fo5 Homo sapiens Endoplasm. reticulum 1 0 2.3 ± 1.4 57 ± 7 -3.9
2.4.06.01. Steroidogenic acute regulatory protein, mitochondrial 3p0l Homo sapiens Mitochon. outer 1 0 3.0 ± 1.3 76 ± 10 -4.7
2.4.06.01. Cholesterol-regulated Start protein 4 (StarD4) 1jss Mus musculus Eukaryo. plasma 1 0 2.7 ± 1.4 68 ± 10 -5.2
2.4.06.01. STAR-related lipid transfer protein from bacteria 3qsz Xanthomonas axonopodis Bact. Gram-neg inner 1 0 3.7 ± 1.4 58 ± 15 -3.0
2.4.06.01. Phosphatidylcholine transfer protein 1ln1 Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 53 ± 16 -4.8
2.4.06.01. StAR-related lipid transfer protein 13 2pso Homo sapiens Eukaryo. plasma 1 0 3.1 ± 4.0 77 ± 27 -4.6
2.4.06.01. StAR-related lipid transfer protein 5 2r55 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 47 ± 19 -4.8
2.4.06.01. STAR-related lipid transfer protein 11, complex with C18 ceramide 2e3q Homo sapiens Golgi 1 0 4.3 ± 2.0 41 ± 17 -3.7
2.4.06.01. STAR-related lipid transfer protein 11, apoprotein (open state) 2e3m Homo sapiens Golgi 1 0 3.4 ± 1.1 44 ± 12 -6.1
2.4.06.01. Lipid transport protein Mln64 (StARD3) 1em2 Homo sapiens Endosome 1 0 2.0 ± 1.1 82 ± 12 -5.0
2.4.06.02. Phosphatidylinositol transfer protein beta isoform 2a1l Rattus norvegicus Eukaryo. plasma 1 0 4.7 ± 1.7 36 ± 17 -4.3
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1kcm Mus musculus Eukaryo. plasma 1 0 5.3 ± 1.4 59 ± 5 -11.0
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1t27 Rattus norvegicus Eukaryo. plasma 1 0 2.3 ± 1.9 12 ± 12 -4.1
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1uw5 Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.5 18 ± 16 -5.4
2.4.06.03. Class 10 plant pathogenesis-related protein 2qim Lupinus luteus Secreted 1 0 3.3 ± 1.4 41 ± 3 -3.1
2.4.06.03. S-norcoclaurine synthase 2vq5 Thalictrum flavum (Yellow meadow rue) Undefined 4 0 2.6 ± 0.3 90 ± 0 -7.0
2.4.06.04. STAR-related bacterial protein 2d4r Thermus thermophilus Bact. Gram-neg inner 1 0 6.9 ± 2.2 28 ± 6 -7.1
2.4.06.04. STAR-related bacterial protein 3ggn Deinococcus radiodurans Undefined 1 0 5.2 ± 1.6 53 ± 8 -4.1
2.4.06.04. STAR-related bacterial protein 1t17 Caulobacter crescentus Undefined 1 0 3.4 ± 0.7 63 ± 2 -8.1
2.4.07.01. NADPH oxidase organizer 1, PX domain 2l73 Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.9 72 ± 13 -5.1
2.4.07.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Homo sapiens Golgi 1 0 2.5 ± 1.3 56 ± 16 -4.8
2.4.07.01. PX domain of serine/threonine-protein kinase Sgk3 1xte Homo sapiens Endosome 1 0 1.2 ± 1.4 77 ± 11 -2.9
2.4.07.01. PX domain of sorting nexin-17 (SNX17) 3fog Homo sapiens Endosome 1 0 3.4 ± 1.0 69 ± 12 -4.9
2.4.07.01. Bud emergence protein 1 2v6v Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.1 ± 1.2 75 ± 6 -5.1
2.4.07.01. PX domain of NADH oxidase (p40phox), ligand-bound 1h6h Homo sapiens Endosome 1 0 3.9 ± 2.0 55 ± 14 -6.0
2.4.07.01. Sorting nexin-5 3hpc Rattus norvegicus Endosome 1 0 0.0 ± 2.1 90 ± 8 -2.4
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-bound 1o7k Homo sapiens Endosome 1 0 15.2 ± 1.7 60 ± 15 -18.4
2.4.07.01. Sorting nexin-23 (Kinesin-like protein KIF16B) 2v14 Homo sapiens Endosome 1 0 3.3 ± 3.0 72 ± 14 -5.4
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens Endosome 1 0 2.4 ± 1.6 88 ± 12 -4.6
2.4.07.01. Nischarin 3p0c Homo sapiens Endosome 1 0 4.1 ± 0.5 82 ± 13 -7.0
2.4.07.01. PX domain of C2alpha-PI3 kinase 2ar5 Homo sapiens Eukaryo. plasma 1 0 5.6 ± 0.9 83 ± 17 -3.7
2.4.07.01. PX domain of sorting nexin GRD19, ligand-bound 1ocu Saccharomyces cerevisiae Endosome 2 0 15.3 ± 0.8 88 ± 6 -34.9
2.4.07.01. PX domain of vacuolar morphogenesis protein VAM7 1kmd Saccharomyces cerevisiae Vacuole 1 0 3.4 ± 1.2 76 ± 8 -7.8
2.4.07.01. Sorting nexin-11, conformation 1 4ikb Homo sapiens Eukaryo. plasma 1 0 5.2 ± 2.7 61 ± 8 -6.1
2.4.07.01. PX domain of sorting nexin GRD19, ligand-free 1ocs Saccharomyces cerevisiae Endosome 1 0 2.5 ± 1.1 88 ± 11 -5.4
2.4.07.01. Sorting nexin-11, conformation 2 4ikd Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.2 58 ± 4 -5.3
2.4.08.01. Eosinophil cationic protein 1h1h Homo sapiens 1 0 3.5 ± 1.0 88 ± 6 -7.3
2.4.09.01. Death-associated protein kinase 1 2w4j Homo sapiens Eukaryo. plasma 1 0 2.1 ± 0.7 86 ± 12 -4.1
2.4.09.01. Calcium/calmodulin-dependent protein kinase type IV 2w4o Homo sapiens Eukaryo. plasma 1 0 3.2 ± 1.2 88 ± 6 -5.6
2.4.09.01. Serine/threonine-protein kinase Nek2 2w5a Homo sapiens Eukaryo. plasma 1 0 2.7 ± 1.5 81 ± 6 -11.2
2.4.11.01. Crambin 1ejg Crambe abyssinica Secreted 1 0 4.0 ± 1.7 79 ± 15 -7.0
2.4.11.01. beta-Purothionin 1bhp Triticum aestivum Secreted 1 0 2.9 ± 2.0 56 ± 19 -4.8
2.4.11.01. Hellethionin D 1nbl Helleborus purpurascens Secreted 1 0 2.2 ± 0.9 45 ± 9 -7.4
2.4.11.01. Alpha-1-purothionin 2plh Triticum aestivum Secreted 1 0 2.4 ± 2.0 53 ± 17 -4.6
2.4.11.01. Viscotoxin A3 1okh Viscum album Secreted 1 0 4.6 ± 1.3 32 ± 19 -4.9
2.4.11.01. Beta-hordothionin 1wuw Hordeum vulgare Secreted 1 0 3.6 ± 1.1 55 ± 15 -5.4
2.4.11.01. Viscotoxin B 1jmp Viscum album Secreted 1 0 1.2 ± 1.4 52 ± 13 -3.2
2.4.11.01. Viscotoxin A1 3c8p Viscum album Secreted 1 0 2.3 ± 0.9 45 ± 7 -4.9
2.4.11.01. Viscotoxin A2 1jmn Viscum album Secreted 1 0 2.3 ± 0.3 63 ± 8 -3.3
2.4.12.01. Liver-expressed antimicrobial peptide 2 2l1q Homo sapiens Secreted 1 0 5.3 ± 1.4 56 ± 11 -2.7
2.4.13.01. Oxysterol-binding protein homolog 4 (KES1) 1zhx Saccharomyces cerevisiae Eukaryo. plasma 1 0 1.2 ± 0.9 90 ± 7 -5.0
2.4.13.01. Oxysterol-binding protein homolog 4 (KES1), N-terminal helix removed 1zi7 Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.5 ± 0.5 75 ± 8 -6.9
2.4.15.01. Protein Nef, complex with T-cell surface glycoprotein CD3 zeta chain 3ik5 Simian immunodeficiency virus Eukaryo. plasma 2 0 3.1 ± 0.5 78 ± 7 -4.5
2.4.15.01. Protein Nef (HIV HV1LW) 2nef Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 6.3 ± 1.4 73 ± 3 -7.9
2.4.15.01. Protein Nef, N-terminal helix (HIV HV1B1) 1zec Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.6 ± 4.1 89 ± 2 -6.8
2.4.15.01. Protein Nef 1avv Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.0 ± 1.5 75 ± 13 -3.4
2.4.15.01. Protein Nef (HIV 9HIV1) 2xi1 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 4.3 ± 0.6 57 ± 5 -5.0
2.4.15.01. Protein Nef, complex with tyrosine-protein kinase SH3 domain (HIV HV1A2) 3rbb Human immunodeficiency virus type 1 Eukaryo. plasma 2 0 2.4 ± 1.1 84 ± 6 -4.2
2.4.16.01. Tx10 alpha-like toxin 1kv0 Buthus martensii Secreted 1 0 1.9 ± 1.1 83 ± 11 -4.6
2.4.16.01. Beta-insect excitatory toxin BmK IT-AP 1t0z Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 3.9 ± 1.2 79 ± 10 -7.2
2.4.16.01. Alpha-mammal toxin BmK-M8 1snb Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.4 ± 2.4 79 ± 22 -2.3
2.4.16.01. LQH III alpha-like toxin 1fh3 Leiurus quinquestriatus hebraeus Secreted 1 0 3.6 ± 1.5 83 ± 16 -5.2
2.4.16.01. Alpha-mammal toxin AaH2 1aho Androctonus australis (Sahara scorpion) Secreted 1 0 1.7 ± 1.0 64 ± 17 -3.4
2.4.16.01. Alpha-like toxin CsEv5 1i6f Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.4 ± 1.3 59 ± 4 -5.8
2.4.16.01. Toxin CsEv3 2sn3 Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.3 74 ± 17 -5.5
2.4.16.01. Alpha-insect toxin Lqq3 1lqq Leiurus quinquestriatus quinquestriatus Secreted 1 0 0.8 ± 1.0 80 ± 6 -3.3
2.4.16.01. Kurtoxin 1t1t Parabuthus transvaalicus Secreted 1 0 3.8 ± 0.8 88 ± 11 -5.9
2.4.16.01. Neurotoxin 2 1jza Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.7 68 ± 15 -5.6
2.4.16.01. Beta-insect excitatory toxin BmKIT1 1wwn Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.2 ± 1.1 72 ± 6 -4.4
2.4.16.01. Beta-toxin CsEI 1b3c Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.9 ± 1.2 70 ± 7 -3.9
2.4.16.01. Alpha-toxin Cn12 1pe4 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.1 ± 2.3 17 ± 13 -3.1
2.4.16.01. Beta-mammal toxin Cn2 2yc1 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.8 ± 1.1 68 ± 9 -3.8
2.4.16.01. Toxin CsEv1 1vna Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.9 ± 1.0 65 ± 10 -7.8
2.4.16.01. Beta-insect depressant toxin LqhIT2 2i61 Leiurus quinquestriatus hebraeus Secreted 1 0 4.3 ± 1.6 80 ± 21 -3.7
2.4.16.01. Alpha-like neurotoxin BmK-I 1djt Buthus martensii Secreted 2 0 3.8 ± 0.9 90 ± 15 -6.9
2.4.16.01. Alpha-insect toxin LqhaIT 2yeo Leiurus quinquestriatus hebraeus Secreted 1 0 3.5 ± 0.8 43 ± 13 -5.9
2.4.16.01. Neurotoxin 1dq7 Buthus tamulus Secreted 1 0 5.9 ± 1.8 88 ± 18 -8.1
2.4.16.01. Beta-toxin Cn5 2kja Centruroides noxius (Mexican scorpion) Secreted 1 0 4.1 ± 1.1 73 ± 6 -7.0
2.4.16.01. Toxin BmKaIT1 1omy Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.0 ± 1.3 83 ± 10 -3.8
2.4.16.01. Toxin VII 1npi Tityus serrulatus Secreted 1 0 4.6 ± 1.5 52 ± 16 -6.7
2.4.16.01. Neurotoxin BmK-M10 2kbk Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 1.7 ± 1.0 73 ± 14 -2.4
2.4.16.01. Alpha-toxin CsE5 1nra Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.3 ± 1.2 89 ± 22 -4.3
2.4.16.01. Toxin Bmka2 2kbj Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.1 ± 1.5 64 ± 15 -3.6
2.4.16.02. Defensin MGD-1 1fjn Mytilus galloprovincialis (Mediterranean mussel) Secreted 1 0 1.5 ± 1.4 43 ± 12 -3.0
2.4.16.02. Phormicin 1ica Protophormia terraenovae (Northern blowfly) Secreted 1 0 3.7 ± 2.3 90 ± 23 -5.0
2.4.16.02. Drosomycin 1myn Drosophila melanogaster Secreted 1 0 4.6 ± 1.2 10 ± 17 -6.0
2.4.16.02. Defensin 2nz3 Anopheles gambiae (African malaria mosquito) Secreted 1 0 6.7 ± 1.3 84 ± 10 -7.4
2.4.16.02. Defensin 2b68 Crassostrea gigas (Pacific oyster) Secreted 1 0 5.8 ± 1.7 28 ± 20 -4.0
2.4.16.02. Nasonin 2koz Nasonia vitripennis (Parasitic wasp) Secreted 1 0 2.9 ± 0.9 68 ± 7 -4.6
2.4.16.02. Defensin ARD1 1ozz Archaeoprepona demophon Secreted 1 0 4.9 ± 1.7 31 ± 17 -7.1
2.4.16.02. Defensin heliomicin 1i2u Heliothis virescens (Tobacco budworm moth) Secreted 1 0 3.4 ± 0.4 59 ± 1 -7.6
2.4.16.02. Sapecin 1l4v Sarcophaga peregrina Secreted 1 0 5.4 ± 1.5 84 ± 18 -5.1
2.4.16.02. Termicin 1mm0 Pseudacanthotermes spiniger Secreted 1 0 4.2 ± 0.5 81 ± 3 -3.3
2.4.16.03. Charybdotoxin 2crd Leiurus quinquestriatus hebraeus Secreted 1 0 1.1 ± 1.5 86 ± 15 -3.2
2.4.16.03. Toxin I5a 1sis Buthus eupeus Secreted 1 0 3.1 ± 1.4 74 ± 16 -4.4
2.4.16.03. Chlorotoxin 1chl Leiurus quinquestriatus quinquestriatus Secreted 1 0 6.5 ± 1.2 87 ± 14 -4.3
2.4.16.03. Potassium channel toxin alpha-KTx 3.1 3odv Androctonus mauretanicus mauretanicus (Scorpion) Secreted 1 0 2.6 ± 0.9 84 ± 5 -5.1
2.4.16.03. Potassium channel toxin gamma-KTx 1.1 1ne5 Centruroides noxius (Mexican scorpion) Secreted 1 0 3.9 ± 1.0 62 ± 2 -5.2
2.4.16.04. Defensin 3psm Pachyrhizus erosus Secreted 1 0 4.1 ± 1.8 32 ± 8 -5.4
2.4.16.04. Defensin 1ti5 Vigna radiata (Mung bean) Secreted 1 0 1.9 ± 2.4 62 ± 16 -3.0
2.4.16.04. Floral defensin-like protein 1 1n4n Petunia hybrida Secreted 1 0 1.8 ± 0.8 6 ± 9 -3.8
2.4.16.04. Defensin 2 (PDF1) 2gl1 Vigna radiata (Mung bean) Secreted 1 0 2.8 ± 0.6 6 ± 4 -5.7
2.4.16.04. Defensin-like protein 195 1jxc Arabidopsis thaliana Secreted 1 0 4.0 ± 1.5 21 ± 20 -3.9
2.4.16.04. Defensin-like protein 1 1gps Triticum aestivum Secreted 1 0 3.4 ± 1.3 22 ± 9 -3.9
2.4.16.04. Antifungal protein 1 1ayj Raphanus sativus Secreted 1 0 11.0 ± 1.9 39 ± 19 -7.4
2.4.16.04. Defensin-like protein 1 1gpt Hordeum vulgare Secreted 1 0 3.1 ± 1.6 28 ± 18 -2.0
2.4.16.04. Defensin 1 1jkz Pisum sativum Secreted 1 0 3.5 ± 1.6 8 ± 19 -5.4
2.4.16.04. Defensin-like protein 1mr4 Nicotiana tabacum Secreted 1 0 4.2 ± 1.8 59 ± 11 -3.0
2.4.16.04. Defensin-like protein 1brz Pentadiplandra brazzeana Secreted 1 0 1.2 ± 1.2 83 ± 10 -3.6
2.4.16.06. Mytilin-B 2eem Mytilus edulis (Blue mussel) Secreted 1 0 3.6 ± 1.4 76 ± 8 -3.2
2.4.16.07. Diapause-specific peptide 2e2f Gastrophysa atrocyanea (Leaf beetle) Secreted 1 0 1.3 ± 1.0 30 ± 10 -4.2
2.4.16.08. Hydramacin-1 2k35 Hydra vulgaris Secreted 1 0 2.0 ± 0.2 87 ± 2 -4.3
2.4.16.09. S-locus pollen protein 1ugl Brassica campestris (Field mustard) Secreted 1 0 1.3 ± 0.6 51 ± 5 -3.4
2.4.16.10. Toxin MIT1 (Black mamba intestinal toxin 1) 1imt Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 4.8 ± 0.7 70 ± 3 -9.1
2.4.16.11. Tertiapin 1ter Apis mellifera Secreted 1 0 5.1 ± 0.3 80 ± 5 -4.6
2.4.16.12. Micasin 2lr5 Arthroderma otae Secreted 1 0 8.3 ± 0.6 58 ± 6 -7.8
2.4.16.12. Plectasin 3e7r Pseudoplectania nigrella (Ebony cup) Secreted 1 0 2.7 ± 2.3 53 ± 17 -4.0
2.4.16.12. Eurocin 2lt8 Eurotium amstelodami Secreted 1 0 5.3 ± 1.3 84 ± 12 -5.5
2.4.17.01. Vitellogenin 1lsh Ichthyomyzon unicuspus (Silver lamprey) Secreted 1 0 3.4 ± 1.3 81 ± 0 -4.6
2.4.18.01. Phospholipase B-like protein 3fgr Mus musculus Lysosome 2 0 6.5 ± 2.4 79 ± 8 -5.3
2.4.19.01. Protein CutA 1osc Rattus norvegicus Eukaryo. plasma 3 0 1.3 ± 0.3 90 ± 1 -5.5
2.4.20.01. Cathepsin F 1m6d Homo sapiens Lysosome 1 0 4.3 ± 0.8 80 ± 3 -11.7
2.4.20.01. Cysteine protease 3ois Xylella fastidiosa Undefined 1 0 3.2 ± 0.2 80 ± 4 -6.4
2.4.20.02. Arylamine N-acetyltransferase 1w5r Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 2.6 ± 0.5 82 ± 6 -6.2
2.4.20.02. Arylamine N-acetyltransferase 1w4t Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 2.8 ± 0.4 82 ± 1 -5.8
2.4.20.03. Protease NSP1 3ifu Porcine reproductive and respiratory syndrome virus Undefined 2 0 5.4 ± 1.2 89 ± 15 -9.8
2.4.20.04. Group XVI phospholipase A1/A2 2kyt Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.5 62 ± 18 -4.9
2.4.21.02. L-alanyl-D-glutamate peptidase 2vo9 Listeria phage A500 Secreted 1 0 3.1 ± 1.0 48 ± 4 -5.2
2.4.23.01. Methyl-accepting chemotaxis protein 3eee Thermoanaerobacter tengcongensis Undefined 1 0 3.2 ± 0.9 81 ± 4 -5.9
2.4.24.01. Mandelate racemase/muconate lactonizing enzyme 1wue Enterococcus faecalis Undefined 2 0 4.0 ± 0.3 86 ± 10 -5.5
2.4.25.01. Uncharacterized N-acetyltransferase SSO0209 2x7b Sulfolobus solfataricus Undefined 1 0 3.9 ± 1.5 49 ± 6 -7.6
2.4.26.01. Putative uncharacterized protein 3nrd Rhizobium meliloti Undefined 2 0 5.8 ± 0.9 86 ± 3 -13.7
2.4.27.01. Gamma-glutamylaminecyclotransferase 1vkb Mus musculus Undefined 1 0 2.3 ± 0.7 72 ± 4 -4.8
2.4.28.01. Phenazine biosynthesis protein PhzF 1s7j Enterococcus faecalis Undefined 1 0 1.8 ± 0.7 77 ± 2 -4.3
2.4.29.01. Superantigen-like protein 3r2t Staphylococcus aureus Undefined 1 0 4.2 ± 0.0 79 ± 1 -6.2
2.4.29.01. Enterotoxin type A 1dyq Staphylococcus aureus Secreted 1 0 3.9 ± 0.5 82 ± 6 -6.8
2.4.30.01. TNF receptor-associated factor 2 1d01 Homo sapiens Eukaryo. plasma 3 0 3.5 ± 0.0 90 ± 0 -5.7
2.4.31.01. Ficolin-1 2wnp Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.8 65 ± 2 -5.3
2.4.32.01. Vanadium chloroperoxidase 3bb0 Curvularia inaequalis Secreted 1 0 3.8 ± 0.8 52 ± 6 -5.3
2.4.33.01. 72 kDa type IV collagenase 1eak Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.6 37 ± 6 -6.6
2.4.33.01. 72 kDa type IV collagenase complex 1gxd Homo sapiens Eukaryo. plasma 2 0 2.5 ± 1.1 77 ± 4 -5.4
2.4.33.01. 72 kDa type IV collagenase 1ck7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 73 ± 9 -4.0
2.4.33.02. Collagenase 2y3u Clostridium histolyticum Secreted 1 0 3.0 ± 1.0 89 ± 4 -5.4
2.4.34.01. Cysteine-rich secretory protein 1rc9 Viridovipera stejnegeri (Chinese green tree viper) Secreted 1 0 3.9 ± 0.7 73 ± 5 -5.1
2.4.35.01. Catalase-related protein 3e4w Mycobacterium paratuberculosis Undefined 2 0 9.6 ± 1.3 49 ± 6 -13.4
2.4.36.01. Transforming growth factor beta-1 3rjr Sus scrofa Secreted 2 0 5.8 ± 2.0 82 ± 16 -9.5
2.4.37.01. Acylphosphatase 1w2i Pyrococcus horikoshii Archaebac. 1 0 2.6 ± 2.7 56 ± 7 -3.9
2.4.38.01. Peptidoglycan recognition protein 3 1sk4 Homo sapiens Secreted 1 0 6.1 ± 1.5 54 ± 7 -8.5
2.4.39.01. Intergenic-region protein 2wj9 Escherichia coli Undefined 2 0 3.9 ± 0.6 83 ± 3 -5.9
2.4.40.01. Transforming protein RhoA 3lxr Shigella flexneri Eukaryo. plasma 2 0 2.7 ± 0.4 75 ± 2 -6.7
2.4.41.01. Hepatitis C virus non-structural protein NS2 2hd0 Hepatitis C virus Endoplasm. reticulum 2 0 6.7 ± 0.6 85 ± 0 -11.8
2.4.42.01. Cholesteryl ester transfer protein 2obd Homo sapiens Secreted 1 0 7.4 ± 2.9 26 ± 6 -7.0
2.4.45.01. Putative uncharacterized protein 2y3c Treponema denticola Undefined 1 0 2.9 ± 0.7 65 ± 4 -5.0
2.4.46.01. Putative uncharacterized protein 3pe5 Clostridium leptum Undefined 1 0 6.7 ± 1.7 83 ± 13 -7.0
2.4.47.01. Neutral ceramidase 2zws Pseudomonas aeruginosa Secreted 1 0 3.1 ± 2.4 77 ± 3 -8.1
2.4.48.01. PPPDE peptidase domain-containing protein 2 3ebq Homo sapiens Undefined 1 0 8.3 ± 2.6 54 ± 6 -7.6
2.4.49.01. Inositol-pentakisphosphate 2-kinase 2xao Arabidopsis thaliana Undefined 1 0 3.2 ± 4.1 55 ± 46 -5.0
2.4.50.01. Matrix protein 1lg7 Vesicular stomatitis virus Viral 1 0 2.7 ± 0.4 82 ± 2 -7.3
2.4.50.01. Matrix protein, different conformation 2w2r Vesicular stomatitis virus Viral 1 0 4.1 ± 0.1 57 ± 1 -10.4
2.4.51.01. Heme acquisition protein HasAp 3mok Pseudomonas aeruginosa Secreted 1 0 4.5 ± 0.7 37 ± 7 -6.7
2.4.52.01. Spondin-2 3d34 Homo sapiens Secreted 1 0 6.3 ± 0.7 35 ± 5 -10.4
2.4.53.01. Resistin 1rfx Mus musculus Secreted 3 0 3.4 ± 1.2 10 ± 6 -8.7
2.4.53.01. Resistin, different conformation 1rgx Mus musculus Secreted 3 0 8.2 ± 1.2 12 ± 6 -12.1
2.4.54.01. Type IV fimbriae assembly protein 3dsg Xanthomonas campestris Secreted 1 0 3.4 ± 1.1 63 ± 5 -6.3