PDB ID or protein name

Alpha + Beta monotopic/peripheral superfamilies

2.4.001. FAD-linked reductases (1 family)
2.4.002. NTF2-like (1 family) CL0051 (Pfam)
2.4.003. Transcriptional factor tubby (1 family) PF01167 (Pfam)
2.4.004. DNase I-like (1 family)
2.4.005. Sterol carrier protein (2 families) CL0311 (Pfam)
2.4.006. Bet v1-like (5 families) CL0209 (Pfam)
2.4.007. PX domain (1 family) PF00787 (Pfam)
2.4.008. Ribonuclease-like (1 family)
2.4.009. Cytomegalovirus assemblin (1 family)
2.4.010. PreATP-grasp domain (1 family)
2.4.011. Plant thionin (1 family) 1.C.44 (TCDB) PF00321 (Pfam)
2.4.012. Liver-expressed antimicrobial peptide (1 family) PF07359 (Pfam)
2.4.013. OSBP-related proteins (1 family) PF01237 (Pfam)
2.4.015. Negative factor (Nef) protein (1 family) PF00469 (Pfam)
2.4.016. Scorpion toxin-like knottin (13 families) CL0054 (Pfam)
2.4.017. Apolipoprotein of LDL particles (1 family) PF01347 (Pfam)
2.4.018. NTN hydrolase superfamily (1 family) CL0052 (Pfam)
2.4.019. GlnB-like superfamily (1 family) CL0089 (Pfam)
2.4.020. Peptidase clan CA (4 families) CL0125 (Pfam)
2.4.021. Peptidase MD (2 families) CL0170 (Pfam)
2.4.022. FAD binding domain (1 family) PF01565 (Pfam)
2.4.023. Heme NO and oxygen binding like (1 family) CL0210 (Pfam)
2.4.024. Enolase like TIM barrel (1 family) CL0256 (Pfam)
2.4.025. N-acetyltransferase like (1 family) CL0257 (Pfam)
2.4.026. HIT superfamily (1 family) CL0265 (Pfam)
2.4.027. AIG2/ChaC-like superfamily (1 family) CL0278 (Pfam)
2.4.028. DAP epimerase superfamily (1 family) CL0288 (Pfam)
2.4.029. Superantigen toxins (1 family) CL0386 (Pfam)
2.4.030. TRAF domain-like superfamily (1 family) CL0389 (Pfam)
2.4.031. Fibrinogen (1 family) CL0422 (Pfam)
2.4.032. Acid phosphatase/Vanadium-dependent haloperoxidase (1 family) CL0525 (Pfam)
2.4.033. PGBD superfamily (2 families) CL0244 (Pfam)
2.4.034. Type III antifreeze protein (1 family) PF08666 (Pfam)
2.4.035. Catalase (1 family) PF00199 (Pfam)
2.4.036. Transforming growth factor (TGF)-beta (1 family) PF00688 (Pfam)
2.4.037. Monalysin (1 family)
2.4.038. PRELI/MSF1 (1 family) PF04707 (Pfam)
2.4.040. IpaB/EvcA family (1 family) PF03278 (Pfam)
2.4.041. Hepatitis C virus non-structural protein NS2 (1 family) PF01538 (Pfam)
2.4.042. Bactericidal permeability increasing protein family (1 family) 1.C.40 (TCDB) PF01273 (Pfam)
2.4.043. OmpA (1 family) PF00691 (Pfam)
2.4.044. Filovirus protein VP24 (1 family) PF06389 (Pfam)
2.4.049. Inositol-pentakisphosphate 2-kinase (1 family) PF06090 (Pfam)
2.4.050. Vesiculovirus matrix protein (1 family) PF06326 (Pfam)
2.4.051. Heme-binding protein A (1 family) PF06438 (Pfam)
2.4.052. Spondin (1 family) PF06468 (Pfam)
2.4.053. Resistin (1 family) PF06954 (Pfam)
See list of these PDB codes

Alpha + Beta monotopic/peripheral (230 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.4.01.01. Cholesterol oxidase 1coy Brevibacterium sterolicum Bact. Gram-pos plas. 1 0 4.4 ± 1.1 43 ± 10 -6.8
2.4.01.01. Cholesterol oxidase 1b4v Streptomyces sp. Bact. Gram-pos plas. 1 0 5.4 ± 0.6 39 ± 4 -8.4
2.4.02.01. Epoxide Hydrolase 2bng Mycobacterium tuberculosis Bact. Gram-pos plas. 2 0 8.2 ± 0.6 88 ± 4 -24.0
2.4.03.01. Tubby protein 3c5n Homo sapiens Eukaryo. plasma 1 0 3.4 ± 0.4 75 ± 5 -7.6
2.4.03.01. Tubby protein, ligand-bound 1i7e Mus musculus Eukaryo. plasma 1 0 3.8 ± 1.9 75 ± 13 -4.7
2.4.03.01. Tubby protein, ligand-free 1c8z Mus musculus Eukaryo. plasma 1 0 2.8 ± 0.9 89 ± 13 -5.8
2.4.03.01. Tubby protein homolog 1s31 Homo sapiens Eukaryo. plasma 1 0 6.8 ± 1.0 71 ± 2 -7.6
2.4.04.01. Sphingomyelinase C 1zwx Listeria ivanovii Secreted 1 0 6.2 ± 0.5 55 ± 1 -10.1
2.4.04.01. Type II inositol-1,4,5-trisphosphate 5-phosphatase 3n9v Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.4 63 ± 6 -6.0
2.4.04.01. Beta-hemolysin 3i48 Staphylococcus aureus Secreted 1 0 2.8 ± 0.8 57 ± 5 -5.1
2.4.04.01. Sphingomyelin phosphodiesterase 3 5uvg Homo sapiens Golgi 1 0 2.9 ± 1.6 59 ± 13 -5.1
2.4.04.01. Inositol polyphosphate 5-phosphatase OCRL-1 4cmn Homo sapiens Endosome 1 0 6.7 ± 1.6 83 ± 2 -9.2
2.4.04.01. Type II inositol 1,4,5-trisphosphate 5-phosphatase 4cml Homo sapiens Endoplasm. reticulum 1 0 4.6 ± 1.1 48 ± 9 -5.1
2.4.04.01. Sphingomyelinase C 2ddt Bacillus cereus Secreted 1 0 4.1 ± 1.1 59 ± 8 -7.6
2.4.05.01. Sterol carrier protein 2 1pz4 Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.8 ± 5.0 37 ± 49 -1.3
2.4.05.01. Sterol carrier protein 2 2cx7 Thermus thermophilus Bact. Gram-neg inner 1 0 4.7 ± 1.3 73 ± 13 -6.9
2.4.05.01. Sterol carrier protein 2 1c44 Oryctolagus cuniculus Eukaryo. plasma 1 0 3.7 ± 1.2 74 ± 17 -4.8
2.4.05.01. Sterol carrier protein 2 like domain of multifunctional enzyme type 2 1ikt Homo sapiens Peroxisome 1 0 3.5 ± 1.2 75 ± 17 -4.0
2.4.05.01. Uncharacterized protein 3bkr Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.4 ± 6.2 50 ± 73 -1.2
2.4.05.01. Uncharacterized protein 3cnu Archaeoglobus fulgidus Archaebac. 1 0 7.6 ± 1.7 69 ± 20 -7.0
2.4.05.01. Sterol carrier protein 2-like 2 2qzt Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 1.0 ± 2.0 45 ± 12 -3.0
2.4.05.02. SDS hydrolase SdsA1 2cfu Pseudomonas aeruginosa Secreted 1 0 6.0 ± 2.5 70 ± 4 -7.0
2.4.06.01. StAR-related lipid transfer protein 13 2pso Homo sapiens Eukaryo. plasma 1 0 3.1 ± 4.0 77 ± 27 -4.6
2.4.06.01. STAR-related lipid transfer protein from bacteria 3qsz Xanthomonas axonopodis Bact. Gram-neg inner 1 0 3.7 ± 1.4 58 ± 15 -3.0
2.4.06.01. Lipid transport protein Mln64 (StARD3) 1em2 Homo sapiens Endosome 1 0 2.0 ± 1.1 82 ± 12 -5.0
2.4.06.01. Acyl-coenzyme A thioesterase 11 3fo5 Homo sapiens Endoplasm. reticulum 1 0 2.3 ± 1.4 57 ± 7 -3.9
2.4.06.01. Steroidogenic acute regulatory protein, mitochondrial 3p0l Homo sapiens Mitochon. outer 1 0 3.0 ± 1.3 76 ± 10 -4.7
2.4.06.01. StAR-related lipid transfer protein 5 2r55 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 47 ± 19 -4.8
2.4.06.01. Cholesterol-regulated Start protein 4 (StarD4) 5brl Mus musculus Eukaryo. plasma 1 0 3.7 ± 1.1 67 ± 13 -3.7
2.4.06.01. STAR-related lipid transfer protein 11, complexes with lipids 2e3q Homo sapiens Golgi 1 0 4.3 ± 2.0 41 ± 17 -3.7
2.4.06.01. Phosphatidylcholine transfer protein 1ln1 Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 53 ± 16 -4.8
2.4.06.01. STAR-related lipid transfer protein 11, apoprotein (open state) 2e3m Homo sapiens Golgi 1 0 3.4 ± 1.1 44 ± 12 -6.1
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1t27 Rattus norvegicus Eukaryo. plasma 1 0 2.3 ± 1.9 12 ± 12 -4.1
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1uw5 Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.5 18 ± 16 -5.4
2.4.06.02. Phosphatidylinositol transfer protein beta isoform 2a1l Rattus norvegicus Eukaryo. plasma 1 0 4.7 ± 1.7 36 ± 17 -4.3
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1kcm Mus musculus Eukaryo. plasma 1 0 5.3 ± 1.4 59 ± 5 -11.0
2.4.06.03. Class 10 plant pathogenesis-related protein 2qim Lupinus luteus Secreted 1 0 3.3 ± 1.4 41 ± 3 -3.1
2.4.06.03. S-norcoclaurine synthase 2vq5 Thalictrum flavum (Yellow meadow rue) Undefined 4 0 2.6 ± 0.3 90 ± 0 -7.0
2.4.06.04. STAR-related bacterial protein 3ggn Deinococcus radiodurans Undefined 1 0 5.2 ± 1.6 53 ± 8 -4.1
2.4.06.04. STAR-related bacterial protein 1t17 Caulobacter crescentus Undefined 1 0 3.4 ± 0.7 63 ± 2 -8.1
2.4.06.04. STAR-related bacterial protein 2d4r Thermus thermophilus Bact. Gram-neg inner 1 0 6.9 ± 2.2 28 ± 6 -7.1
2.4.06.05. Thermoacidophile-specific fatty acid carrier 3w9k Sulfolobus tokodaii Archaebac. 1 0 2.7 ± 1.4 47 ± 4 -7.1
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens Endosome 1 0 2.4 ± 1.6 88 ± 12 -4.6
2.4.07.01. PX domain of vacuolar morphogenesis protein VAM7 1kmd Saccharomyces cerevisiae Vacuole 1 0 3.4 ± 1.2 76 ± 8 -7.8
2.4.07.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Homo sapiens Golgi 1 0 2.5 ± 1.3 56 ± 16 -4.8
2.4.07.01. PX domain of sorting nexin-14 4bgj Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 72 ± 22 -4.3
2.4.07.01. PX domain of sorting nexin GRD19, ligand-bound 1ocu Saccharomyces cerevisiae Endosome 2 0 15.3 ± 0.8 88 ± 6 -34.9
2.4.07.01. Bud emergence protein 1 2v6v Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.1 ± 1.2 75 ± 6 -5.1
2.4.07.01. PX domain of sorting nexin GRD19, ligand-free 1ocs Saccharomyces cerevisiae Endosome 1 0 2.5 ± 1.1 88 ± 11 -5.4
2.4.07.01. PX domain of serine/threonine-protein kinase Sgk3 1xte Homo sapiens Endosome 1 0 1.2 ± 1.4 77 ± 11 -2.9
2.4.07.01. PX domain of sorting nexin-17 (SNX17) 3fog Homo sapiens Endosome 1 0 3.4 ± 1.0 69 ± 12 -4.9
2.4.07.01. Sorting nexin-5 3hpc Rattus norvegicus Endosome 1 0 0.0 ± 2.1 90 ± 8 -2.4
2.4.07.01. PX domain of C2alpha-PI3 kinase 2ar5 Homo sapiens Eukaryo. plasma 1 0 5.6 ± 0.9 83 ± 17 -3.7
2.4.07.01. Sorting nexin-23 (Kinesin-like protein KIF16B) 2v14 Homo sapiens Endosome 1 0 3.3 ± 3.0 72 ± 14 -5.4
2.4.07.01. Nischarin 3p0c Homo sapiens Endosome 1 0 4.1 ± 0.5 82 ± 13 -7.0
2.4.07.01. NADPH oxidase organizer 1, PX domain 2l73 Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.9 72 ± 13 -5.1
2.4.07.01. Sorting nexin-11, conformation 1 4ikb Homo sapiens Eukaryo. plasma 1 0 5.2 ± 2.7 61 ± 8 -6.1
2.4.07.01. PX domain of NADH oxidase (p40phox), ligand-bound 1h6h Homo sapiens Endosome 1 0 3.9 ± 2.0 55 ± 14 -6.0
2.4.07.01. Sorting nexin-11, conformation 2 4ikd Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.2 58 ± 4 -5.3
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-bound 1o7k Homo sapiens Endosome 1 0 15.2 ± 1.7 60 ± 15 -18.4
2.4.07.01. PX domain of sorting nexin-10 4on3 Homo sapiens Endosome 1 0 5.2 ± 1.6 69 ± 5 -7.7
2.4.08.01. Eosinophil cationic protein 1h1h Homo sapiens 1 0 3.5 ± 1.0 88 ± 6 -7.3
2.4.09.01. T4 capsid assembly protease, gp21 5jbl Enterobacteria phage T4 Viral 5 0 3.6 ± 0.2 89 ± 0 -12.0
2.4.11.01. Crambin, enantiomer 3ue7 Designed proteins Undefined 1 0 3.4 ± 1.7 89 ± 13 -4.6
2.4.11.01. Crambin 1ejg Crambe abyssinica Secreted 1 0 4.0 ± 1.7 79 ± 15 -7.0
2.4.11.01. Beta-hordothionin 1wuw Hordeum vulgare Secreted 1 0 3.6 ± 1.1 55 ± 15 -5.4
2.4.11.01. beta-Purothionin 1bhp Triticum aestivum Secreted 1 0 2.9 ± 2.0 56 ± 19 -4.8
2.4.11.01. Viscotoxin A1 3c8p Viscum album Secreted 1 0 2.3 ± 0.9 45 ± 7 -4.9
2.4.11.01. Hellethionin D 1nbl Helleborus purpurascens Secreted 1 0 2.2 ± 0.9 45 ± 9 -7.4
2.4.11.01. Alpha-1-purothionin 2plh Triticum aestivum Secreted 1 0 2.4 ± 2.0 53 ± 17 -4.6
2.4.11.01. Viscotoxin A3 1okh Viscum album Secreted 1 0 4.6 ± 1.3 32 ± 19 -4.9
2.4.11.01. Viscotoxin B 1jmp Viscum album Secreted 1 0 1.2 ± 1.4 52 ± 13 -3.2
2.4.11.01. Viscotoxin A2 1jmn Viscum album Secreted 1 0 2.3 ± 0.3 63 ± 8 -3.3
2.4.12.01. Liver-expressed antimicrobial peptide 2 2l1q Homo sapiens Secreted 1 0 5.3 ± 1.4 56 ± 11 -2.7
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 2 4ph7 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.5 ± 0.9 75 ± 2 -6.4
2.4.13.01. Protein Osh1 5h2d Kluyveromyces lactis Vacuole 1 0 0.4 ± 2.4 71 ± 26 -2.7
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 2 1zhy Saccharomyces cerevisiae Golgi 1 0 0.9 ± 0.4 87 ± 4 -4.7
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 3 4jch Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.2 88 ± 1 -6.0
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 4 3spw Saccharomyces cerevisiae Golgi 1 0 7.3 ± 1.1 60 ± 9 -4.5
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 1 1zhx Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.9 90 ± 7 -5.0
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 1 4b2z Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.3 ± 1.3 86 ± 6 -4.6
2.4.13.01. Oxysterol-binding protein homolog 4 (KES1), N-terminal helix removed 1zi7 Saccharomyces cerevisiae Golgi 1 0 2.5 ± 0.5 75 ± 8 -6.9
2.4.13.01. Oxysterol-binding protein homolog 3 4ic4 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 4.3 ± 0.9 86 ± 29 -5.9
2.4.15.01. Protein Nef, complex with T-cell surface glycoprotein CD3 zeta chain 3ik5 Simian immunodeficiency virus Eukaryo. plasma 2 0 3.1 ± 0.5 78 ± 7 -4.5
2.4.15.01. Protein Nef (HIV HV1LW) 2nef Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 6.3 ± 1.4 73 ± 3 -7.9
2.4.15.01. Protein Nef, N-terminal helix (HIV HV1B1) 1zec Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.6 ± 4.1 89 ± 2 -6.8
2.4.15.01. Protein Nef 1avv Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.0 ± 1.5 75 ± 13 -3.4
2.4.15.01. Protein Nef (HIV 9HIV1) 2xi1 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 4.3 ± 0.6 57 ± 5 -5.0
2.4.15.01. Protein Nef, complex with tyrosine-protein kinase SH3 domain (HIV HV1A2) 3rbb Human immunodeficiency virus type 1 Eukaryo. plasma 2 0 2.4 ± 1.1 84 ± 6 -4.2
2.4.16.01. Toxin Bmka2 2kbj Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.1 ± 1.5 64 ± 15 -3.6
2.4.16.01. Alpha-insect toxin LqhaIT 2yeo Leiurus quinquestriatus hebraeus Secreted 1 0 3.5 ± 0.8 43 ± 13 -5.9
2.4.16.01. Beta-mammal toxin Cn2 2yc1 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.8 ± 1.1 68 ± 9 -3.8
2.4.16.01. Beta-insect excitatory toxin BmKIT1 1wwn Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.2 ± 1.1 72 ± 6 -4.4
2.4.16.01. Beta-toxin Cn5 2kja Centruroides noxius (Mexican scorpion) Secreted 1 0 4.1 ± 1.1 73 ± 6 -7.0
2.4.16.01. Alpha-like neurotoxin BmK-I 1djt Buthus martensii Secreted 2 0 3.8 ± 0.9 90 ± 15 -6.9
2.4.16.01. Alpha-toxin CsE5 1nra Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.3 ± 1.2 89 ± 22 -4.3
2.4.16.01. Neurotoxin 1dq7 Buthus tamulus Secreted 1 0 5.9 ± 1.8 88 ± 18 -8.1
2.4.16.01. Alpha-mammal toxin BmK-M8 1snb Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.4 ± 2.4 79 ± 22 -2.3
2.4.16.01. Toxin VII 1npi Tityus serrulatus Secreted 1 0 4.6 ± 1.5 52 ± 16 -6.7
2.4.16.01. Alpha-like toxin CsEv5 1i6f Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.4 ± 1.3 59 ± 4 -5.8
2.4.16.01. Tx10 alpha-like toxin 1kv0 Buthus martensii Secreted 1 0 1.9 ± 1.1 83 ± 11 -4.6
2.4.16.01. Neurotoxin BmK-M10 2kbk Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 1.7 ± 1.0 73 ± 14 -2.4
2.4.16.01. Kurtoxin 1t1t Parabuthus transvaalicus Secreted 1 0 3.8 ± 0.8 88 ± 11 -5.9
2.4.16.01. LQH III alpha-like toxin 1fh3 Leiurus quinquestriatus hebraeus Secreted 1 0 3.6 ± 1.5 83 ± 16 -5.2
2.4.16.01. Beta-insect excitatory toxin BmK IT-AP 1t0z Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 3.9 ± 1.2 79 ± 10 -7.2
2.4.16.01. Alpha-toxin Cn12 1pe4 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.1 ± 2.3 17 ± 13 -3.1
2.4.16.01. Alpha-mammal toxin AaH2 1aho Androctonus australis (Sahara scorpion) Secreted 1 0 1.7 ± 1.0 64 ± 17 -3.4
2.4.16.01. Beta-insect depressant toxin LqhIT2 2i61 Leiurus quinquestriatus hebraeus Secreted 1 0 4.3 ± 1.6 80 ± 21 -3.7
2.4.16.01. Alpha-insect toxin Lqq3 1lqq Leiurus quinquestriatus quinquestriatus Secreted 1 0 0.8 ± 1.0 80 ± 6 -3.3
2.4.16.01. Tau-theraphotoxin-Hs1a 2n9z Haplopelma schmidti Secreted 1 0 6.1 ± 1.3 68 ± 10 -5.6
2.4.16.01. Beta-toxin CsEI 1b3c Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.9 ± 1.2 70 ± 7 -3.9
2.4.16.01. Toxin CsEv3 2sn3 Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.3 74 ± 17 -5.5
2.4.16.01. Toxin BmKaIT1 1omy Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.0 ± 1.3 83 ± 10 -3.8
2.4.16.01. Toxin CsEv1 1vna Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.9 ± 1.0 65 ± 10 -7.8
2.4.16.01. Neurotoxin 2 1jza Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.7 68 ± 15 -5.6
2.4.16.02. Coprisin 2ln4 Copris tripartitus Secreted 1 0 4.5 ± 0.6 42 ± 4 -5.3
2.4.16.02. Defensin MGD-1 1fjn Mytilus galloprovincialis (Mediterranean mussel) Secreted 1 0 1.5 ± 1.4 43 ± 12 -3.0
2.4.16.02. Defensin 2nz3 Anopheles gambiae (African malaria mosquito) Secreted 1 0 6.7 ± 1.3 84 ± 10 -7.4
2.4.16.02. Defensin 2b68 Crassostrea gigas (Pacific oyster) Secreted 1 0 5.8 ± 1.7 28 ± 20 -4.0
2.4.16.02. Defensin heliomicin 1i2u Heliothis virescens (Tobacco budworm moth) Secreted 1 0 3.4 ± 0.4 59 ± 1 -7.6
2.4.16.02. Termicin 1mm0 Pseudacanthotermes spiniger Secreted 1 0 4.2 ± 0.5 81 ± 3 -3.3
2.4.16.02. Phormicin 1ica Protophormia terraenovae (Northern blowfly) Secreted 1 0 3.7 ± 2.3 90 ± 23 -5.0
2.4.16.02. Nasonin 2koz Nasonia vitripennis (Parasitic wasp) Secreted 1 0 2.9 ± 0.9 68 ± 7 -4.6
2.4.16.02. Drosomycin 1myn Drosophila melanogaster Secreted 1 0 4.6 ± 1.2 10 ± 17 -6.0
2.4.16.02. Defensin ARD1 1ozz Archaeoprepona demophon Secreted 1 0 4.9 ± 1.7 31 ± 17 -7.1
2.4.16.02. Lucifensin 2lld Lucilia sericata Secreted 1 0 1.1 ± 1.7 11 ± 12 -3.0
2.4.16.02. Sapecin 1l4v Sarcophaga peregrina Secreted 1 0 5.4 ± 1.5 84 ± 18 -5.1
2.4.16.03. Potassium channel toxin alpha-KTx 3.1 3odv Androctonus mauretanicus mauretanicus (Scorpion) Secreted 1 0 2.6 ± 0.9 84 ± 5 -5.1
2.4.16.03. Charybdotoxin 2crd Leiurus quinquestriatus hebraeus Secreted 1 0 1.1 ± 1.5 86 ± 15 -3.2
2.4.16.03. Toxin I5a 1sis Buthus eupeus Secreted 1 0 3.1 ± 1.4 74 ± 16 -4.4
2.4.16.03. Chlorotoxin 1chl Leiurus quinquestriatus quinquestriatus Secreted 1 0 6.5 ± 1.2 87 ± 14 -4.3
2.4.16.03. Potassium channel toxin gamma-KTx 1.1 1ne5 Centruroides noxius (Mexican scorpion) Secreted 1 0 3.9 ± 1.0 62 ± 2 -5.2
2.4.16.04. Defensin-like protein 1 1ayj Raphanus sativus Secreted 1 0 11.0 ± 1.9 39 ± 19 -7.4
2.4.16.04. Floral defensin-like protein 1 1n4n Petunia hybrida Secreted 1 0 1.8 ± 0.8 6 ± 9 -3.8
2.4.16.04. Flower-specific defensin, monomer 4ab0 Nicotiana alata (Winged tobacco) Secreted 1 0 3.5 ± 1.2 55 ± 13 -4.3
2.4.16.04. Defensin 1 1jkz Pisum sativum Secreted 1 0 3.5 ± 1.6 8 ± 19 -5.4
2.4.16.04. Defensin 2 (PDF1) 2gl1 Vigna radiata (Mung bean) Secreted 1 0 2.8 ± 0.6 6 ± 4 -5.7
2.4.16.04. Defensin Lc-def 2lj7 Lens culinaris Secreted 1 0 2.2 ± 0.9 22 ± 10 -3.9
2.4.16.04. Defensin-like protein 1brz Pentadiplandra brazzeana Secreted 1 0 1.2 ± 1.2 83 ± 10 -3.6
2.4.16.04. Defensin NsD7 5kk4 Nicotiana tabacum Secreted 2 0 3.5 ± 0.7 80 ± 4 -5.6
2.4.16.04. Defensin-like protein 1 1gps Triticum aestivum Secreted 1 0 3.4 ± 1.3 22 ± 9 -3.9
2.4.16.04. Flower-specific gamma-thionin-like protein 4uj0 Solanum lycopersicum Secreted 1 0 2.6 ± 0.9 19 ± 5 -4.8
2.4.16.04. Defensin-like protein 1 1gpt Hordeum vulgare Secreted 1 0 3.1 ± 1.6 28 ± 18 -2.0
2.4.16.04. Defensin-like protein 32 2mz0 Arabidopsis thaliana Secreted 1 0 2.6 ± 1.4 19 ± 8 -3.4
2.4.16.04. Defensin NaD1 1mr4 Nicotiana tabacum Secreted 1 0 4.2 ± 1.8 59 ± 11 -3.0
2.4.16.04. Defensin-like protein 195 1jxc Arabidopsis thaliana Secreted 1 0 4.0 ± 1.5 21 ± 20 -3.9
2.4.16.04. Defensin 3psm Pachyrhizus erosus Secreted 1 0 4.1 ± 1.8 32 ± 8 -5.4
2.4.16.04. Defensin-like protein 2 2n2r Raphanus sativus Secreted 1 0 2.5 ± 1.7 31 ± 24 -4.2
2.4.16.04. Defensin 1ti5 Vigna radiata (Mung bean) Secreted 1 0 1.9 ± 2.4 62 ± 16 -3.0
2.4.16.04. Flower-specific defensin, dimer 4cqk Nicotiana alata (Winged tobacco) Secreted 2 0 3.7 ± 1.2 79 ± 9 -6.3
2.4.16.05. Micasin 2lr5 Arthroderma otae Secreted 1 0 8.3 ± 0.6 58 ± 6 -7.8
2.4.16.05. Plectasin 3e7r Pseudoplectania nigrella (Ebony cup) Secreted 1 0 2.7 ± 2.3 53 ± 17 -4.0
2.4.16.05. Eurocin 2lt8 Eurotium amstelodami Secreted 1 0 5.3 ± 1.3 84 ± 12 -5.5
2.4.16.06. Mytilin-B 2eem Mytilus edulis (Blue mussel) Secreted 1 0 3.6 ± 1.4 76 ± 8 -3.2
2.4.16.07. Diapause-specific peptide 2e2f Gastrophysa atrocyanea (Leaf beetle) Secreted 1 0 1.3 ± 1.0 30 ± 10 -4.2
2.4.16.08. Theromacin 2ln8 Hirudo medicinalis Secreted 1 0 3.7 ± 0.2 72 ± 3 -6.4
2.4.16.08. Hydramacin-1 2k35 Hydra vulgaris Secreted 1 0 2.0 ± 0.2 87 ± 2 -4.3
2.4.16.09. S-locus pollen protein 1ugl Brassica campestris (Field mustard) Secreted 1 0 1.3 ± 0.6 51 ± 5 -3.4
2.4.16.10. Toxin MIT1 (Black mamba intestinal toxin 1) 1imt Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 4.8 ± 0.7 70 ± 3 -9.1
2.4.16.11. Tertiapin 1ter Apis mellifera Secreted 1 0 5.1 ± 0.3 80 ± 5 -4.6
2.4.16.12. Actinomycesin 2ru0 Actinomyces sp. Secreted 1 0 3.5 ± 0.7 83 ± 7 -4.1
2.4.16.13 Copsin 2mn5 Coprinopsis cinerea Secreted 1 0 3.0 ± 1.5 59 ± 9 -5.9
2.4.17.01. Vitellogenin 1lsh Ichthyomyzon unicuspus (Silver lamprey) Secreted 1 0 3.4 ± 1.3 81 ± 0 -4.6
2.4.18.01. Phospholipase B-like protein 3fgr Mus musculus Lysosome 2 0 6.5 ± 2.4 79 ± 8 -5.3
2.4.19.01. Protein CutA 1osc Rattus norvegicus Eukaryo. plasma 3 0 1.3 ± 0.3 90 ± 1 -5.5
2.4.20.01. Cysteine protease 3ois Xylella fastidiosa Undefined 1 0 3.2 ± 0.2 80 ± 4 -6.4
2.4.20.01. Cathepsin F 1m6d Homo sapiens Lysosome 1 0 4.3 ± 0.8 80 ± 3 -11.7
2.4.20.02. Arylamine N-acetyltransferase 1w4t Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 2.8 ± 0.4 82 ± 1 -5.8
2.4.20.02. Arylamine N-acetyltransferase 1w5r Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 2.6 ± 0.5 82 ± 6 -6.2
2.4.20.03. Protease NSP1 3ifu Porcine reproductive and respiratory syndrome virus Undefined 2 0 5.4 ± 1.2 89 ± 15 -9.8
2.4.20.04. Group XVI phospholipase A1/A2 2kyt Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.5 62 ± 18 -4.9
2.4.21.02. L-alanyl-D-glutamate peptidase 2vo9 Listeria phage A500 Secreted 1 0 3.1 ± 1.0 48 ± 4 -5.2
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase 4fdo Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 4.3 ± 1.1 67 ± 4 -5.3
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase, another loop disordered 4ff6 Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 3.4 ± 1.5 19 ± 6 -6.4
2.4.23.01. Methyl-accepting chemotaxis protein 3eee Thermoanaerobacter tengcongensis Undefined 1 0 3.2 ± 0.9 81 ± 4 -5.9
2.4.24.01. Mandelate racemase/muconate lactonizing enzyme 1wue Enterococcus faecalis Undefined 2 0 4.0 ± 0.3 86 ± 10 -5.5
2.4.25.01. N-alpha-acetyltransferase 60, structure 1 5hgz Homo sapiens Golgi 1 0 5.7 ± 1.1 41 ± 7 -8.5
2.4.25.01. N-alpha-acetyltransferase 60, structure 2 5hh0 Homo sapiens Golgi 1 0 5.2 ± 0.0 46 ± 1 -10.7
2.4.25.01. Uncharacterized N-acetyltransferase SSO0209 2x7b Sulfolobus solfataricus Undefined 1 0 3.9 ± 1.5 49 ± 6 -7.6
2.4.26.01. Putative uncharacterized protein 3nrd Rhizobium meliloti Undefined 2 0 5.8 ± 0.9 86 ± 3 -13.7
2.4.27.01. Gamma-glutamylaminecyclotransferase 1vkb Mus musculus Undefined 1 0 2.3 ± 0.7 72 ± 4 -4.8
2.4.28.01. Phenazine biosynthesis protein PhzF 1s7j Enterococcus faecalis Undefined 1 0 1.8 ± 0.7 77 ± 2 -4.3
2.4.29.01. Superantigen-like protein 3r2t Staphylococcus aureus Undefined 1 0 4.2 ± 0.0 79 ± 1 -6.2
2.4.29.01. Enterotoxin type A 1dyq Staphylococcus aureus Secreted 1 0 3.9 ± 0.5 82 ± 6 -6.8
2.4.30.01. TNF receptor-associated factor 2 1d01 Homo sapiens Eukaryo. plasma 3 0 3.5 ± 0.0 90 ± 0 -5.7
2.4.31.01. Ficolin-1 2wnp Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.8 65 ± 2 -5.3
2.4.32.01. Vanadium chloroperoxidase 3bb0 Curvularia inaequalis Secreted 1 0 3.8 ± 0.8 52 ± 6 -5.3
2.4.33.01. 72 kDa type IV collagenase, complex with inhibitor-2 1gxd Homo sapiens Eukaryo. plasma 2 0 2.5 ± 1.1 77 ± 4 -5.4
2.4.33.01. 72 kDa type IV collagenase, full-length 1ck7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 73 ± 9 -4.0
2.4.33.01. 72 kDa type IV collagenase, 32-452 1eak Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.6 37 ± 6 -6.6
2.4.33.02. Collagenase 2y3u Clostridium histolyticum Secreted 1 0 3.0 ± 1.0 89 ± 4 -5.4
2.4.34.01. Type III antifreeze protein nfeAFP11 2lx2 Zoarces elongatus Secreted 1 0 5.3 ± 1.0 53 ± 5 -7.0
2.4.34.01. Type-3 ice-structuring protein HPLC 12 4ny6 Zoarces americanus Secreted 1 0 3.3 ± 0.8 58 ± 9 -5.8
2.4.34.01. Ice-structuring protein RD3 1c89 Lycodichthys dearborni Secreted 1 0 3.0 ± 1.0 85 ± 9 -8.7
2.4.34.01. Ice-structuring protein SP2(HPLC 1) 1ops Zoarces americanus Secreted 1 0 2.4 ± 1.4 60 ± 12 -4.8
2.4.34.01. Ice-structuring protein RD1 1ucs Lycodichthys dearborni Secreted 1 0 2.2 ± 1.0 67 ± 9 -5.5
2.4.34.01. Ice-structuring protein 4ur4 Zoarces viviparus Secreted 1 0 3.2 ± 4.1 68 ± 2 -5.8
2.4.35.01. 8R-Lipoxygenase, N-terminal domain 1u5u Plexaura homomalla Eukaryo. plasma 1 0 3.1 ± 0.3 72 ± 3 -10.4
2.4.35.01. Catalase-related protein 3e4w Mycobacterium paratuberculosis Undefined 2 0 9.6 ± 1.3 49 ± 6 -13.4
2.4.36.01. Transforming growth factor beta-1 3rjr Sus scrofa Secreted 2 0 5.8 ± 2.0 82 ± 16 -9.5
2.4.37.01. Monalysin 4mjt Pseudomonas entomophila Secreted 9 0 1.6 ± 0.0 90 ± 0 -13.5
2.4.38.01. Ups1 transporter-Mdm35 complex, structure 1 4xiz Saccharomyces cerevisiae Mitochon. inner 2 0 2.0 ± 1.7 19 ± 13 -4.1
2.4.38.01. Ups1 transporter-Mdm35 complex, structure 2 4ytx Saccharomyces cerevisiae Mitochon. inner 2 0 5.4 ± 1.0 78 ± 0 -6.3
2.4.40.01. IpgB2 protein 3lxr Shigella flexneri Bact. Gram-neg inner 2 0 2.7 ± 0.4 75 ± 2 -6.7
2.4.41.01. Hepatitis C virus non-structural protein NS2 (955-1026) 2hd0 Hepatitis C virus Endoplasm. reticulum 2 0 6.7 ± 0.6 85 ± 0 -11.8
2.4.42.01. Cholesteryl ester transfer protein 2obd Homo sapiens Secreted 1 0 7.4 ± 2.9 26 ± 6 -7.0
2.4.42.01. Bactericidal permeability-increasing protein 1bp1 Homo sapiens Secreted 1 0 1.5 ± 2.4 51 ± 17 -4.3
2.4.42.01. Latherin 3zpm Equus caballus Secreted 1 0 6.0 ± 0.4 75 ± 1 -8.0
2.4.43.01. Cell wall anchor protein of the T6SS system 4b62 Pseudomonas aeruginosa Bact. Gram-neg outer 1 0 2.8 ± 2.5 46 ± 36 -4.6
2.4.44.01. Membrane-associated protein VP24, with karyopherin 4u2x Zaire ebolavirus Viral 2 0 4.5 ± 2.1 33 ± 15 -4.3
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 2 4axd Arabidopsis thaliana Eukaryo. plasma 1 0 1.5 ± 0.1 88 ± 4 -4.0
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 3 4axc Arabidopsis thaliana Eukaryo. plasma 1 0 3.2 ± 2.3 68 ± 15 -4.5
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 1 2xar Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 1.6 69 ± 7 -6.1
2.4.50.01. Matrix protein, Indiana virus 1lg7 Vesicular stomatitis virus Viral 1 0 2.7 ± 0.4 82 ± 2 -7.3
2.4.50.01. Matrix protein, New Jersey virus 2w2r Vesicular stomatitis virus Viral 1 0 4.1 ± 0.1 57 ± 1 -10.4
2.4.50.01. Matrix protein, Indiana virus, complex with mRNA export factor 4owr Vesicular stomatitis virus Viral 1 0 2.1 ± 0.8 65 ± 2 -7.6
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 2 5iqw Pseudomonas aeruginosa Secreted 1 0 1.5 ± 0.2 24 ± 5 -4.8
2.4.51.01. Heme acquisition protein HasA 4xzd Yersinia pseudotuberculosis Secreted 1 0 3.5 ± 0.4 25 ± 2 -5.9
2.4.51.01. Heme acquisition protein HasA, alternative position of heme 3mol Pseudomonas aeruginosa Secreted 1 0 2.9 ± 0.6 40 ± 5 -5.8
2.4.51.01. Heme acquisition protein HasA, dimer 4y4s Yersinia pseudotuberculosis Secreted 1 0 1.8 ± 1.1 83 ± 9 -4.2
2.4.51.01. Heme acquisition protein HasA 3ell Pseudomonas aeruginosa Secreted 1 0 3.3 ± 0.4 18 ± 8 -5.5
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 1 3mok Pseudomonas aeruginosa Secreted 1 0 4.5 ± 0.7 37 ± 7 -6.7
2.4.51.01. Heme acquisition protein HasA, apoprotein 1ybj Serratia marcescens Secreted 1 0 2.8 ± 2.4 33 ± 9 -3.9
2.4.51.01. Heme acquisition protein HasA 1b2v Serratia marcescens Secreted 1 0 1.9 ± 1.6 18 ± 18 -3.3
2.4.51.01. Heme acquisition protein HasA, different strain 3wah Pseudomonas aeruginosa Secreted 1 0 3.4 ± 0.6 14 ± 3 -5.1
2.4.51.01. Heme acquisition protein HasA 4jet Yersinia pestis Secreted 1 0 4.8 ± 0.9 29 ± 2 -7.0
2.4.51.01. Heme acquisition protein HasA, apoprotein 4jes Yersinia pestis Secreted 1 0 5.2 ± 0.3 40 ± 2 -9.6
2.4.52.01. Spondin-2 3d34 Homo sapiens Secreted 1 0 6.3 ± 0.7 35 ± 5 -10.4
2.4.53.01. Resistin 1rfx Mus musculus Secreted 3 0 3.4 ± 1.2 10 ± 6 -8.7
2.4.53.01. Resistin, different conformation 1rgx Mus musculus Secreted 3 0 8.2 ± 1.2 12 ± 6 -12.1