PDB ID or protein name

Alpha-helical peptides superfamilies

3.1.001. Topogenic peptides (6 families)
3.1.002. Peptide fragments of transmembrane proteins (16 families)
3.1.003. Membrane anchor helices of peripheral proteins (11 families)
3.1.004. Peptide fragments of water-soluble proteins (10 families)
3.1.005. Designed alpha-helical peptides (13 families)
3.1.006. Apolipoprotein peptides (2 families)
3.1.007. Viral fusion and anchor peptides (10 families)
3.1.008. Antifreeze protein, type I (1 family)
3.1.009. Herpesvirus US12 family (1 family) PF05363 (Pfam)
3.1.010. Alpha-helical bacterial pheromones (1 family)
3.1.011. Peptide hormones (6 families)
3.1.012. Endothelin-like peptides (1 family) PF00322 (Pfam)
3.1.013. Calcitonin (1 family) 1.C.49 (TCDB) PF00214 (Pfam)
3.1.014. Tachykinin family (1 family) PF02202 (Pfam)
3.1.015. Bacteriocin, class IIa (5 families) PF01721 (Pfam)
3.1.016. Bacteriocin, class IIb (1 family)
3.1.017. Bacterial antimicrobial peptides (1 family)
3.1.018. Hemolysing bacterial toxins (2 families)
3.1.019. Peptaibol (1 family) 1.D.5 (TCDB)
3.1.020. Alpha-conotoxin-like (1 family)
3.1.021. Insect antimicrobial peptides (11 families)
3.1.022. Mollusc antimicrobial peptides (1 family)
3.1.023. Meucin (1 family)
3.1.024. Penaeidin (1 family) PF05927 (Pfam)
3.1.025. Latarcin (1 family) PF10279 (Pfam)
3.1.026. Pleurocidin (1 family) 1.C.62 (TCDB) PF08107 (Pfam)
3.1.027. Pardaxin (1 family) PF07425 (Pfam)
3.1.028. Amphibian antimicrobial peptides (9 families)
3.1.029. Cathelicidin (3 families) 1.C.33 (TCDB) PF00666 (Pfam)
3.1.030. Lactotransferrin peptides (1 family)
3.1.031. Dermcidin (1 family) PF15291 (Pfam)
3.1.032. Toxin-antitoxin module (1 family) 1.C.103 (TCDB)
3.1.033. Stage V sporulation protein (1 family) PF08183 (Pfam)
3.1.034. Conotoxin B (1 family)
3.1.035. Plant alpha-helical antimicrobial peptides (1 family)
See list of these PDB codes

Alpha-helical peptides (374 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
3.1.19.01. Gichigamin 4z0w Tolypocladium sp. Secreted 2 2 31.2 ± 4.4 49 ± 7 -34.5
3.1.31.01. Dermcidin, crystal structure 2ymk Homo sapiens Secreted 1 0 4.8 ± 1.3 90 ± 0 -31.0
3.1.02.02. TM peptide (1567-1594) of voltage-gated sodium channel Nav1.4 5jr0 Rattus norvegicus Eukaryo. plasma 1 1 30.8 ± 3.2 39 ± 2 -26.2
3.1.02.05. Glycine receptor, alpha-1 subunit, TMH 2+3 1vry Homo sapiens Eukaryo. plasma 1 2 23.2 ± 3.7 5 ± 9 -25.3
3.1.32.01. Toxic peptide of toxin-antitoxin system (PEPA1) 4b19 Staphylococcus aureus Bact. Gram-pos plas. 1 1 18.8 ± 4.5 62 ± 2 -23.8
3.1.02.05. Acetylcholine receptor, subunit alpha, TMH II 1dxz Torpedo californica Eukaryo. plasma 1 1 29.8 ± 3.6 25 ± 4 -23.1
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 405-424 1btq Homo sapiens Eukaryo. plasma 1 0 13.6 ± 2.1 67 ± 11 -22.5
3.1.07.02. Transmembrane domain of HIV-1 gp41 (677-716), trimer 5jyn Human immunodeficiency virus type 1 Viral 3 3 36.0 ± 1.6 0 ± 2 -22.0
3.1.02.05. Acetylcholine receptor, subunit beta2, TMH 1 2k58 Homo sapiens Eukaryo. plasma 1 1 30.6 ± 6.0 39 ± 7 -22.0
3.1.05.12. Designed transmembrane metallotransporter 4p6j Designed proteins Undefined 2 2 22.8 ± 2.0 3 ± 1 -21.9
3.1.02.05. Acetylcholine receptor, subunit alpha, TMH 3 3mra Torpedo californica Eukaryo. plasma 1 1 31.6 ± 3.3 35 ± 9 -21.7
3.1.02.07. Na(+)/H(+) antiporter, TMH IV 2m7x Saccharomyces cerevisiae Eukaryo. plasma 1 1 23.0 ± 3.1 9 ± 2 -21.2
3.1.02.05. Acetylcholine receptor, subunit beta2, TMH 2 2k59 Homo sapiens Eukaryo. plasma 1 1 30.2 ± 1.9 20 ± 4 -21.0
3.1.02.08. High affinity copper uptake protein 1, peptide 132-157 2ls3 Homo sapiens Eukaryo. plasma 1 1 20.8 ± 3.4 43 ± 1 -20.8
3.1.07.07. Fusion protein p14, FAST 2lx0 Reptilian orthoreovirus Eukaryo. plasma 1 1 27.4 ± 2.3 17 ± 9 -20.2
3.1.07.01. Fusion peptide (683-704) of protein gp41 2mg1 Human immunodeficiency virus type 1 Endosome 1 1 30.8 ± 0.5 19 ± 3 -19.4
3.1.07.05. Nonstructural protein 4b, segment 1938-1965 of polyprotein 2kdr Hepatitis C virus Endoplasm. reticulum 1 1 22.4 ± 2.0 48 ± 2 -19.1
3.1.02.08. High affinity copper uptake protein 1, peptide 64-84 2ls2 Homo sapiens Eukaryo. plasma 1 1 25.2 ± 4.2 21 ± 9 -19.0
3.1.07.10. Structural peptide 1 of bursal disease virus 2imu Avian infectious bursal disease virus Eukaryo. plasma 1 0 11.6 ± 4.0 76 ± 5 -17.5
3.1.18.02. Phenol-soluble modulin alpha 3 peptide 5kgy Staphylococcus aureus Secreted 1 0 9.4 ± 1.0 73 ± 7 -17.3
3.1.19.01. Alamethicin 1amt Trichoderma viride Secreted 1 0 10.9 ± 2.9 74 ± 13 -17.1
3.1.02.01. Cannabinoid receptor 2, TMH 6 2ki9 Homo sapiens Eukaryo. plasma 1 1 28.4 ± 2.2 21 ± 9 -17.0
3.1.02.01. Apelin receptor, peptide 1-55 2low Homo sapiens Eukaryo. plasma 1 1 26.4 ± 5.1 35 ± 2 -16.7
3.1.01.03. Viral core-E1 signal peptide 2lif Hepatitis C virus Viral 1 1 29.6 ± 5.0 19 ± 10 -16.6
3.1.07.02. Ebola virus envelope glycoprotein, 632-676 5t42 Zaire ebolavirus Viral 1 0 9.1 ± 3.6 71 ± 0 -16.4
3.1.05.02. Self-assembling lipopeptide detergent 3cay Designed proteins Undefined 2 0 14.5 ± 1.3 78 ± 9 -16.4
3.1.26.01. Piscidin 1 2ojm Morone saxatilis Secreted 1 0 10.6 ± 1.0 82 ± 13 -16.3
3.1.07.05. Nonstructural protein 5b, segment 2982-3011 2n1p Hepatitis C virus Eukaryo. plasma 1 1 24.0 ± 2.5 21 ± 3 -16.1
3.1.07.01. Fusion peptide (512-541) of protein gp41 2ari Human immunodeficiency virus type 1 Endosome 1 0 10.0 ± 1.0 88 ± 9 -16.1
3.1.07.06. NS2 protease, segment 845-869 of polyprotein 2mkb Hepatitis GB virus Eukaryo. plasma 1 1 23.2 ± 3.5 30 ± 9 -15.7
3.1.29.01. Cathelicidin LL-37 2k6o Homo sapiens Secreted 1 0 8.1 ± 0.4 86 ± 8 -15.7
3.1.07.06. NS2 protease, segment 869-908 of polyprotein 2kwz Hepatitis C virus Endoplasm. reticulum 1 1 29.8 ± 1.6 59 ± 7 -15.7
3.1.07.06. NS2 protease, segment 836-868 of polyprotein 2kwt Hepatitis C virus Endoplasm. reticulum 1 0 9.5 ± 3.6 81 ± 3 -15.7
3.1.07.06. NS2 protease, segment 734-763 of polyprotein 2lzp Hepatitis GB virus Eukaryo. plasma 1 1 30.8 ± 0.5 32 ± 7 -15.6
3.1.29.01. Antimicrobial protein CAP18, segment 135-166 1lyp Oryctolagus cuniculus Secreted 1 0 7.4 ± 1.0 87 ± 9 -15.6
3.1.28.07. Hylin-A1 2n0o Hypsiboas albopunctatus Secreted 1 0 11.4 ± 0.8 62 ± 4 -15.4
3.1.19.01. Cephaibol B 1ob6 Acremonium tubakii Secreted 1 0 15.0 ± 5.0 42 ± 17 -15.3
3.1.19.01. Samarosporin I 4g13 Samarospora rostrup Secreted 1 0 16.7 ± 1.5 64 ± 14 -15.3
3.1.28.04. Phylloseptin-2 2jpy Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 5.8 ± 1.3 86 ± 4 -15.2
3.1.28.06. Magainin 2, Ala-analogue 4mgp Designed proteins Secreted 1 0 10.0 ± 4.1 79 ± 2 -15.1
3.1.07.05. Nonstructural protein 5a, segment 1973-2003 1r7g Human hepatitis C virus Endoplasm. reticulum 1 0 5.3 ± 0.9 90 ± 5 -15.1
3.1.07.01. Fusion peptide (671-693) of protein gp41 2mg2 Human immunodeficiency virus type 1 Endosome 1 1 22.2 ± 1.9 34 ± 1 -15.1
3.1.19.01. Zervamicin IIb, transmembrane orientation 1r9u Emericellopsis salmosynnemata Secreted 1 1 23.2 ± 5.4 38 ± 7 -15.0
3.1.05.10. WALP19 - Pro8 peptide 2lco Designed proteins Undefined 1 0 9.0 ± 0.4 85 ± 4 -15.0
3.1.19.01. Cephaibol C 1ob7 Acremonium tubakii Secreted 1 0 15.0 ± 2.1 55 ± 21 -15.0
3.1.07.02. Juxtamembrane peptide (657-683) of protein gp160 2me1 Human immunodeficiency virus type 1 Endosome 1 0 7.7 ± 3.8 82 ± 1 -15.0
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 436-456 1bts Homo sapiens Eukaryo. plasma 1 0 9.2 ± 0.3 84 ± 2 -14.8
3.1.19.01. Cephaibol A 1ob4 Acremonium tubakii Secreted 1 0 14.1 ± 2.5 58 ± 18 -14.7
3.1.07.02. Membrane proximal peptide of gp41 (95-121) 2ncs Human immunodeficiency virus type 1 Viral 1 0 20.8 ± 2.0 28 ± 3 -14.6
3.1.19.01. Paracelsin X 4by8 Trichoderma reesei Secreted 1 0 14.6 ± 5.1 60 ± 4 -14.6
3.1.07.03. Hemagglutinin, fusion peptide 346-365, H1 subtype 2kxa Influenza virus Viral 1 0 10.3 ± 1.9 84 ± 13 -14.5
3.1.19.01. Trichotoxin a50e 1m24 Trichoderma viride Secreted 1 0 10.4 ± 1.8 75 ± 32 -14.3
3.1.28.04. Ranatuerin-2csa 2k10 Rana temporaria Secreted 1 0 10.4 ± 1.2 74 ± 5 -14.3
3.1.02.05. Acetylcholine receptor, subunit delta, TMH 2 1a11 Rattus norvegicus Eukaryo. plasma 1 1 24.4 ± 5.6 17 ± 10 -14.2
3.1.07.02. gp41-M-MAT, a membrane associated MPER trimer 2lp7 Human immunodeficiency virus type 1 Viral 3 3 26.8 ± 0.9 1 ± 1 -14.2
3.1.02.05. Glycine receptor alpha-1 subunit, TMH-2 1mot Homo sapiens Eukaryo. plasma 1 1 21.4 ± 1.4 5 ± 3 -14.2
3.1.28.02. Alyteserin-1C 2l5r Alytes obstetricans Secreted 1 0 8.7 ± 4.1 81 ± 0 -14.1
3.1.07.02. Juxtamembrane peptide (671-697) of protein gp160 2me4 Human immunodeficiency virus type 1 Endosome 1 0 7.9 ± 2.9 81 ± 4 -14.0
3.1.28.06. Magainin analogue 1 5cgn Designed proteins Undefined 2 0 6.1 ± 2.7 88 ± 6 -14.0
3.1.03.05. Anchor helix of 1,2-diacylglycerol 3-glucosyltransferase 1z2t Acholeplasma laidlawii Bact. Gram-pos plas. 1 0 9.6 ± 1.6 90 ± 4 -13.7
3.1.28.06. Magainin 2 2mag Xenopus laevis Secreted 1 0 10.1 ± 0.9 81 ± 14 -13.7
3.1.29.01. Cathelicidin-6 2ket Bos taurus Secreted 1 0 7.1 ± 0.7 82 ± 3 -13.6
3.1.07.08. Peptide of outer capsid glycoprotein VP7 (266-326) 2lm7 Rotavirus A Endoplasm. reticulum 1 0 10.2 ± 1.5 76 ± 0 -13.6
3.1.28.04. Phylloseptin-1 2jq0 Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 9.5 ± 1.4 76 ± 7 -13.5
3.1.07.02. Juxtamembrane peptide (662-683) of protein gp41 2pv6 Human immunodeficiency virus type 1 Endosome 1 0 6.7 ± 0.6 82 ± 2 -13.5
3.1.04.10. TAR DNA-binding protein 43, peptide 307-349 2n2c Homo sapiens Nuclear inner 1 0 7.7 ± 0.7 89 ± 6 -13.4
3.1.19.01. Bergofungin A 5mas Emericellopsis donezkii Secreted 1 1 30.8 ± 1.5 35 ± 20 -13.2
3.1.01.03. N-terminal helix of prion-like protein doppel 1z65 Mus musculus Eukaryo. plasma 1 1 21.0 ± 6.2 8 ± 4 -13.2
3.1.07.01. Probable fusion peptide (93-126, 138-160) of protein gp41 2mk3 Human immunodeficiency virus type 1 Endosome 1 2 20.8 ± 0.5 18 ± 1 -13.2
3.1.07.02. Juxtamembrane peptide (651-677) of protein gp160 2me2 Human immunodeficiency virus type 1 Endosome 1 0 7.0 ± 1.1 82 ± 7 -13.1
3.1.28.05. Peptoid analogue of maculatin 2mmj Litoria genimaculata Secreted 1 0 10.0 ± 4.6 73 ± 3 -13.1
3.1.21.05. Poneratoxin 1g92 Paraponera clavata Secreted 1 0 22.8 ± 8.5 29 ± 7 -12.9
3.1.26.01. Pleurocidin 1z64 Pseudopleuronectes americanus Secreted 1 0 5.4 ± 1.3 87 ± 18 -12.8
3.1.18.02. Phenol-soluble modulin alpha-1 5khb Staphylococcus aureus Secreted 1 0 9.4 ± 0.8 71 ± 4 -12.7
3.1.07.03. Antimicrobial peptide derived from hemagglutinin 2l24 Influenza virus Undefined 1 0 8.7 ± 1.3 75 ± 10 -12.6
3.1.05.10. WALP19 - Pro10 peptide 2lcn Designed proteins Undefined 1 1 29.6 ± 6.6 15 ± 7 -12.5
3.1.02.15. Glutamate receptor ionotropic, NMDA 1, TMH 2 2nr1 Homo sapiens Eukaryo. plasma 1 0 7.0 ± 3.7 84 ± 0 -12.5
3.1.10.01. Competence stimulating peptide 2i2h Streptococcus mutants Secreted 1 0 8.2 ± 0.5 74 ± 7 -12.5
3.1.07.02. Juxtamembrane peptide (636-662) of protein gp160 2me3 Human immunodeficiency virus type 1 Endosome 1 0 6.1 ± 0.4 81 ± 7 -12.4
3.1.21.01. Aedesin 2mmm Aedes aegypti (Yellowfever mosquito) Secreted 1 1 20.8 ± 0.8 11 ± 3 -12.3
3.1.21.06. Stomoxyn 1zrx Stomoxys calcitrans (Stable fly) Secreted 1 0 5.7 ± 0.0 80 ± 0 -12.3
3.1.19.01. Zervamicin IIb 1ih9 Emericellopsis salmosynnemata Secreted 1 0 11.5 ± 2.0 74 ± 10 -12.3
3.1.19.01. Chrysospermin C 1ee7 Apiocrea chrysosperma Secreted 1 0 9.8 ± 2.3 82 ± 12 -12.2
3.1.06.02. Amphipathic alpha-helix of apolipoprotein 2irg Designed proteins Undefined 1 0 6.4 ± 1.7 83 ± 15 -12.1
3.1.03.03. Anticancer peptide designed based on the helix of phosphotransferase IIA 1vm2 Designed proteins Undefined 1 0 7.0 ± 1.8 78 ± 15 -12.0
3.1.21.03. Melittin 2mlt Apis mellifera Secreted 1 0 15.0 ± 1.0 65 ± 11 -12.0
3.1.21.03. Melittin, with organometallic fragment 2mw6 Apis mellifera Secreted 1 1 24.2 ± 2.4 6 ± 2 -11.8
3.1.07.05. Nonstructural protein 5a 2ajo Bovine viral diarrhea virus Endoplasm. reticulum 1 0 5.0 ± 1.0 86 ± 15 -11.8
3.1.28.08. Ocellatin-K1 5u9x Leptodactylus knudseni Secreted 1 0 7.4 ± 0.2 77 ± 4 -11.8
3.1.01.03. N-terminal helix of prion-like protein doppel 2m1j Ovis aries Eukaryo. plasma 1 1 23.8 ± 2.6 31 ± 7 -11.7
3.1.04.03. Viral protein R, peptide 59-86 1dsk Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 9.5 ± 0.4 65 ± 6 -11.7
3.1.15.03. Bacteriocin peptide plantaricin F (PlnF) 2rlw Lactobacillus plantarum Secreted 1 0 8.7 ± 4.4 79 ± 5 -11.7
3.1.02.11. Methyl-accepting chemotaxis protein II 2l9g Escherichia coli Bact. Gram-neg inner 1 0 8.1 ± 4.2 75 ± 0 -11.7
3.1.19.01. Antiamoebin I 1joh Emercelliopsis sp. Secreted 1 0 8.1 ± 0.8 82 ± 5 -11.7
3.1.13.01. Calcitonin-1 2glg Oncorhynchus keta (Chum salmon) Secreted 1 0 6.1 ± 0.8 84 ± 4 -11.7
3.1.28.05. Aurein 1.2 analogue 2f3a Designed proteins Undefined 1 0 3.0 ± 1.6 88 ± 24 -11.7
3.1.13.01. Calcitonin 2jxz Homo sapiens Secreted 1 0 5.5 ± 1.1 72 ± 6 -11.5
3.1.21.08. Moricin 2jr8 Manduca sexta Secreted 1 0 5.9 ± 1.6 75 ± 3 -11.5
3.1.02.01. Peptide 171-197 of parathyroid hormone receptor 1bl1 Homo sapiens Eukaryo. plasma 1 1 20.8 ± 1.2 19 ± 4 -11.5
3.1.07.05. Nonstructural protein 4b, segment 1716-1755 2lvg Hepatitis C virus Viral 1 0 6.4 ± 0.7 82 ± 8 -11.4
3.1.07.06. NS2 protease, segment 810-837 of polyprotein 2jy0 Hepatitis C virus Endoplasm. reticulum 1 1 23.8 ± 2.9 14 ± 4 -11.4
3.1.21.01. Cecropin B analogue 2igr Hyalophora cecropia (Cecropia moth) Secreted 1 0 5.1 ± 3.6 87 ± 0 -11.3
3.1.16.01. Lactococcin-G subunit beta 2jpm Lactococcus lactis Secreted 1 0 6.7 ± 3.3 86 ± 0 -11.2
3.1.28.08. Ocellatin-LB2 5ua7 Leptodactylus labyrinthicus Secreted 1 0 7.0 ± 4.4 78 ± 2 -11.1
3.1.27.01. Pardaxin 2kns Pardachirus marmoratus Secreted 1 0 4.0 ± 0.7 84 ± 7 -11.1
3.1.07.03. Hemagglutinin, fusion peptide 346-365, G1S 1xop Influenza virus Viral 1 0 6.3 ± 0.5 70 ± 13 -11.0
3.1.01.06. Protein PB1-F2, mitochondrial targeting peptide (50-87) 2hn8 Influenza virus Mitochon. inner 1 0 5.1 ± 3.8 86 ± 1 -10.9
3.1.07.01. Fusion peptide (510-532) of protein gp41 2pjv Human immunodeficiency virus type 1 Endosome 1 0 8.7 ± 3.8 64 ± 4 -10.9
3.1.07.02. Envelope glycoprotein gp41 2x7r Human immunodeficiency virus type 1 Viral 3 0 5.5 ± 1.1 0 ± 10 -10.9
3.1.07.01. Fusion peptide of spike glycoprotein (758-820) 5xjk Human SARS coronavirus Endosome 1 0 4.1 ± 1.4 82 ± 2 -10.9
3.1.11.02. Glucagon-like peptide 2 2l64 Homo sapiens Secreted 1 0 3.9 ± 0.3 90 ± 5 -10.8
3.1.07.01. Fusion peptide of spike glycoprotein (772-787) 2rum Human SARS coronavirus Endosome 1 0 11.1 ± 1.1 57 ± 13 -10.8
3.1.28.06. Magainin analogue 2 5cgo Designed proteins Undefined 2 0 3.8 ± 0.9 89 ± 2 -10.8
3.1.01.03. Major prion protein, segment 1-30 1skh Bos taurus Eukaryo. plasma 1 1 20.8 ± 6.3 9 ± 5 -10.7
3.1.07.01. Fusion peptide of spike glycoprotein (1185-1201) 2run Human SARS coronavirus Endosome 1 0 6.8 ± 4.0 74 ± 7 -10.7
3.1.07.02. Paramyxovirus sv5 fusion protein core 1svf Simian virus 5 Viral 6 0 8.4 ± 0.9 0 ± 11 -10.7
3.1.28.03. Bombinin-H5 2ap8 Bombina variegata (Yellow-bellied toad) Secreted 1 0 8.6 ± 4.2 77 ± 3 -10.6
3.1.07.05. Nonstructural protein 4b, segment 1751-1780 2jxf Hepatitis C virus Endoplasm. reticulum 1 0 5.6 ± 3.6 85 ± 2 -10.6
3.1.21.09. Cytotoxic linear peptide IsCT 1t51 Opisthacanthus madagascariensis Secreted 1 0 4.1 ± 0.6 87 ± 11 -10.5
3.1.17.01. Antimicrobial peptide HP 1p0l Helicobacter pylori Secreted 1 0 5.3 ± 0.6 79 ± 9 -10.5
3.1.07.03. Hemagglutinin, fusion peptide 346-365, G13A 2l4g Influenza virus Viral 1 0 11.1 ± 0.4 73 ± 4 -10.4
3.1.28.07. Hylin-A1 analogs 5j6v Hypsiboas albopunctatus Secreted 1 0 21.2 ± 2.2 33 ± 16 -10.4
3.1.04.03. Viral protein R, peptide 34-51 1kzt Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.4 ± 0.6 77 ± 7 -10.3
3.1.21.08. Moricin 1kv4 Bombyx mori Secreted 1 0 6.1 ± 0.6 77 ± 14 -10.3
3.1.02.01. Third extracellular loop of cholecystokinin A receptor 1hzn Homo sapiens Eukaryo. plasma 1 0 3.4 ± 0.9 81 ± 2 -10.3
3.1.09.01. ICP47 protein, active domain (1-34) 1qlo Human herpesvirus Endoplasm. reticulum 1 0 8.6 ± 0.8 58 ± 8 -10.2
3.1.05.09. Histidine-rich peptide LAH4 2kjn Designed proteins Undefined 1 0 10.5 ± 6.3 89 ± 2 -10.2
3.1.07.02. Peptide of envelope glycoprotein H (625-644) 2lqy Human herpesvirus Endosome 1 0 3.2 ± 0.8 88 ± 5 -10.2
3.1.13.01. Islet amyloid polypeptide, fragment 34-70 2kb8 Homo sapiens Secreted 1 0 3.9 ± 4.2 90 ± 1 -10.2
3.1.07.05. Nonstructural protein, membrane-bound domain 1fw5 Semiliki forest virus Endosome 1 0 7.9 ± 1.5 73 ± 17 -10.2
3.1.05.03. Glycosaminoglycan-binding (KYE) peptide 2ncw Designed proteins Undefined 1 0 5.0 ± 0.4 84 ± 6 -10.1
3.1.08.01. Antifreeze protein A 1wfb Pseudopleuronectes americanus Secreted 1 0 2.8 ± 1.0 88 ± 1 -10.1
3.1.19.01. Trichovirin 3sbn Hypocrea rufa Secreted 1 1 26.9 ± 2.3 6 ± 3 -10.1
3.1.02.01. C-terminal helix of MCP-1 receptor 2mlo Homo sapiens Eukaryo. plasma 1 0 6.0 ± 1.6 86 ± 8 -10.1
3.1.28.08. Ocellatin-F1 5ua8 Leptodactylus labyrinthicus Secreted 1 0 6.1 ± 0.8 71 ± 7 -10.0
3.1.33.01. Stage V sporulation protein M 2mvh Bacillus subtilis Vacuole 1 0 6.3 ± 1.0 90 ± 4 -9.9
3.1.07.02. Juxtamembrane peptide (684-719) of protein gp41 2kzq Hepatitis C virus Endosome 1 0 4.3 ± 3.3 88 ± 0 -9.9
3.1.15.01. Carnobacteriocin B2 1cw5 Carnobacterium maltaromaticum Secreted 1 0 6.5 ± 0.3 89 ± 5 -9.9
3.1.02.02. Voltage sensor of calcium-activated potassium channel 2k44 Homo sapiens Eukaryo. plasma 1 0 7.5 ± 3.0 54 ± 4 -9.8
3.1.04.01. Protein STE5, peptide 44-67 2kgn Saccharomyces cerevisiae Eukaryo. plasma 1 0 6.4 ± 0.9 84 ± 7 -9.8
3.1.21.02. Mastoparan 2czp Vespa xanthoptera Secreted 1 0 5.2 ± 1.6 88 ± 16 -9.8
3.1.28.05. Aurein 1.2 1vm5 Litoria aurea Secreted 1 0 9.5 ± 1.8 63 ± 14 -9.7
3.1.29.01. LL-37-derived peptide 2l5m Designed proteins Undefined 1 0 6.1 ± 1.0 89 ± 7 -9.7
3.1.27.01. Pardaxin, different conformation 1xc0 Pardachirus marmoratus Secreted 1 1 20.8 ± 5.4 42 ± 2 -9.6
3.1.28.04. Gaegurin-4 2g9l Glandirana rugosa (Japanese wrinkled frog) Secreted 1 0 8.9 ± 4.0 71 ± 3 -9.6
3.1.31.01. Dermcidin, structure 2 2ndk Homo sapiens Secreted 1 0 3.0 ± 2.0 86 ± 4 -9.6
3.1.13.01. Islet amyloid polypeptide, fragment 34-70, alternative structure 2l86 Homo sapiens Secreted 1 0 6.2 ± 0.8 88 ± 7 -9.6
3.1.28.04. Antimicrobial peptide AY1C 5ykl Odorrana andersonii Secreted 1 0 8.1 ± 2.8 67 ± 12 -9.5
3.1.04.07. Peptide (2-25) of antifreeze protein Afp1 2lq0 Glaciozyma antarctica Undefined 1 0 4.0 ± 3.8 85 ± 2 -9.5
3.1.28.04. Phylloseptin-3 2jq1 Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 6.4 ± 0.8 74 ± 9 -9.5
3.1.25.01. Latarcin-1 (M-zodatoxin-Lt1a) 2pco Lachesana tarabaevi (Spider) Secreted 1 0 10.1 ± 0.8 77 ± 6 -9.4
3.1.15.02. Plantaricin-A 1ytr Lactobacillus plantarum Secreted 1 0 9.0 ± 0.5 78 ± 10 -9.4
3.1.07.09. Membrane fusion protein p15 2mns Baboon orthoreovirus Eukaryo. plasma 1 0 9.3 ± 7.0 86 ± 4 -9.4
3.1.05.11. ALPS-23 peptide 2m0w Designed proteins Undefined 1 0 5.7 ± 0.5 72 ± 6 -9.4
3.1.03.11. Toll/interleukin-1 receptor domain-containing adapter protein 5t7q Homo sapiens Eukaryo. plasma 1 0 4.6 ± 1.3 75 ± 6 -9.3
3.1.07.01. Fusion peptide (517-539) of protein gp41 1p5a Human immunodeficiency virus type 1 Endosome 1 1 25.8 ± 5.5 12 ± 3 -9.3
3.1.04.04. Peptide of huntigtin, 1-17 2ld2 Homo sapiens Eukaryo. plasma 1 0 4.2 ± 0.6 90 ± 4 -9.3
3.1.04.02. Major prion protein, peptide 110-136 2lbg Homo sapiens Eukaryo. plasma 1 0 5.0 ± 7.0 86 ± 1 -9.3
3.1.29.01. Ovispirin-1 1hu5 Ovis aries Secreted 1 0 5.7 ± 0.5 81 ± 1 -9.2
3.1.28.09. Pseudin-2, structure 2 2ncx Pseudis paradoxa Secreted 1 0 4.4 ± 4.4 85 ± 13 -9.2
3.1.21.08. Moricin 1x22 Spodoptera litura Secreted 1 0 4.4 ± 1.1 70 ± 5 -9.2
3.1.03.09. Peptide (2-11) of ADP-ribosylation factor 6, in micelle 2bau Homo sapiens Eukaryo. plasma 1 0 11.2 ± 0.9 22 ± 4 -9.1
3.1.14.01. Scyliorhinin-1 2nou Scyliorhinus canicula (Small-spotted catshark) Secreted 1 0 8.6 ± 1.4 81 ± 10 -9.1
3.1.02.02. Sodium channel protein type 3 subunit alpha, TMH 2 1qg9 Rattus norvegicus Eukaryo. plasma 1 0 6.8 ± 0.4 86 ± 3 -9.0
3.1.15.04. Bacteriocin plantaricin J (PlnJ) 2khg Lactobacillus plantarum Secreted 1 0 5.4 ± 4.0 72 ± 2 -9.0
3.1.07.01. Fusion peptide of spike glycoprotein (983-887) 2ruo Human SARS coronavirus Endosome 1 0 9.9 ± 4.0 72 ± 6 -9.0
3.1.28.06. Magainin analogue, MSI-594 2k98 Designed proteins Undefined 1 0 3.2 ± 0.2 86 ± 2 -8.9
3.1.05.06. Transportan 1smz Designed proteins Undefined 1 0 9.1 ± 0.8 87 ± 7 -8.9
3.1.21.02. Decoralin 2n9a Oreumenes decoratus Secreted 1 0 6.7 ± 1.7 86 ± 11 -8.9
3.1.29.01. Fowlicidin-2 2gdl Gallus gallus Secreted 1 0 3.1 ± 0.5 85 ± 4 -8.9
3.1.01.02. Leader peptide of patellamide protein 2kya Prochloron didemni Secreted 1 0 5.8 ± 0.5 86 ± 4 -8.8
3.1.04.07. Peptide (70-94) of antifreeze protein Afp1 2lq1 Glaciozyma antarctica Undefined 1 0 6.2 ± 4.3 87 ± 1 -8.8
3.1.06.02. Class A amphipathic helical peptide 2fq5 Designed proteins Undefined 1 0 6.5 ± 1.4 78 ± 6 -8.8
3.1.21.11. HYL-20 peptide 5mmk Hylaeus signatus Secreted 1 0 4.9 ± 2.8 81 ± 8 -8.8
3.1.13.01. Calcitonin 1bku Anguilla japonica (Japanese eel) Secreted 1 0 3.0 ± 0.4 77 ± 3 -8.7
3.1.29.01. Cathelicidin-1 2amn Gallus gallus Secreted 1 0 5.0 ± 3.3 68 ± 4 -8.7
3.1.29.01. Crotalicidin 2mwt Crotalus durissus terrificus Secreted 1 0 5.2 ± 2.4 86 ± 1 -8.6
3.1.04.03. Viral protein R, peptide 13-33, different strain 1fi0 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 2.7 ± 1.2 88 ± 8 -8.6
3.1.11.01. Neuropeptide Y 1ron Homo sapiens Secreted 1 0 7.9 ± 1.6 74 ± 10 -8.6
3.1.04.03. Viral protein R, peptide 52-96, dimer, different strain 1x9v Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.2 ± 0.7 86 ± 4 -8.6
3.1.04.07. Peptide (119-148) of antifreeze protein Afp1 2lq2 Glaciozyma antarctica Undefined 1 0 1.7 ± 2.4 84 ± 6 -8.6
3.1.21.10. Pilosulin-1 5x3l Myrmecia pilosula Secreted 1 0 7.6 ± 3.2 82 ± 7 -8.5
3.1.07.04. Envelope glycoprotein E1, heterodimerization peptide (350-370) 1emz Hepatitis C virus Viral 1 0 6.2 ± 0.2 86 ± 9 -8.5
3.1.18.01. Delta-hemolysin 1dtc Staphylococcus aureus Secreted 1 0 3.2 ± 2.2 87 ± 19 -8.5
3.1.21.02. Anoplin 2mjq Anoplius samariensis Secreted 1 0 5.6 ± 1.1 85 ± 8 -8.4
3.1.01.04. Ferredoxin, chloroplastic, transit peptide (1-32) 1fct Chlamydomonas reinhardtii Thylakoid 1 1 21.8 ± 6.7 28 ± 4 -8.4
3.1.03.01. Myc box-dependent-interacting protein 1, membrane anchor helix (peptide 1-33) 2rnd Homo sapiens Eukaryo. plasma 1 0 4.0 ± 0.4 85 ± 2 -8.4
3.1.15.04. Bacteriocin plantaricin K (PlnK) 2keg Lactobacillus plantarum Secreted 1 0 3.3 ± 1.1 83 ± 11 -8.4
3.1.01.01. Kalata-B3/B6 propeptide 1wn8 Oldenlandia affinis Secreted 1 0 3.6 ± 1.2 81 ± 22 -8.4
3.1.28.04. Temporin-A 2maa Rana temporaria Secreted 1 0 7.2 ± 0.5 66 ± 7 -8.4
3.1.29.02. Indolicidin, with P->A substitution 1hr1 Designed proteins Undefined 1 0 5.4 ± 4.0 84 ± 9 -8.3
3.1.05.08. MSI-594 derived peptide MSI-594-F5A 2l36 Designed proteins Undefined 1 0 6.9 ± 7.0 79 ± 3 -8.3
3.1.29.01. KR-12 from cathelicidin LL-37 2na3 Homo sapiens Secreted 1 0 3.7 ± 0.7 84 ± 8 -8.3
3.1.02.01. Beta-1 adrenergic receptor, peptide 345-359 1dep Meleagris gallopavo Eukaryo. plasma 1 0 4.4 ± 1.2 76 ± 16 -8.3
3.1.05.03. Antimicrobial peptide PaDBS1R1 2n9r Designed proteins Undefined 1 0 5.6 ± 1.0 83 ± 6 -8.3
3.1.14.01. Uperolein 2gfr Uperoleia rugosa (Wrinkled toadlet) Secreted 1 0 6.4 ± 1.2 88 ± 9 -8.2
3.1.11.01. Neuropeptide Y analogue 1icy Sus scrofa Secreted 1 0 6.4 ± 0.5 69 ± 6 -8.1
3.1.29.03. Tritrpticin 1d6x Sus scrofa Secreted 1 0 9.4 ± 2.6 81 ± 38 -8.1
3.1.07.02. Juxtamembrane peptide (659-685) of protein gp160 2fx7 Human immunodeficiency virus type 1 Endosome 1 0 6.2 ± 1.0 73 ± 7 -8.0
3.1.07.02. Juxtamembrane peptide (665-683) of protein gp41 1jau Human immunodeficiency virus type 1 Endosome 1 0 4.0 ± 4.2 86 ± 2 -8.0
3.1.29.01. Cathelicidin-3, peptide 121-151 2hfr Gallus gallus Secreted 1 0 3.1 ± 4.2 86 ± 1 -8.0
3.1.07.03. Hemagglutinin, fusion peptide 346-365, wild type 1ibn Influenza virus Viral 1 0 9.1 ± 1.2 67 ± 7 -8.0
3.1.28.04. Esculentin-1A, structure 1 2n6m Pelophylax esculentus Secreted 1 0 7.9 ± 0.4 67 ± 5 -7.9
3.1.21.04. Spiderine-1a 2n85 Oxyopes takobius (Lynx spider) Secreted 1 0 3.2 ± 4.2 88 ± 0 -7.8
3.1.05.03. GLFDIVKKVVGALG 5mxl Designed proteins Undefined 1 0 5.0 ± 0.4 86 ± 6 -7.8
3.1.24.01. Penaeidin-4d 1xv3 Litopenaeus setiferus (Atlantic white shrimp) Secreted 1 0 3.4 ± 2.7 76 ± 17 -7.8
3.1.03.03. Membrane-bound helix of phosphotransferase IIA component 1o53 Escherichia coli Bact. Gram-neg inner 1 0 3.3 ± 1.3 86 ± 15 -7.8
3.1.05.03. Peptide F 1pef Designed proteins Undefined 1 0 6.6 ± 1.3 85 ± 10 -7.8
3.1.02.04. V-type proton ATPase subunit a, vacuolar isoform, TMH 7 2jtw Saccharomyces cerevisiae Vacuole 1 1 20.8 ± 6.5 8 ± 7 -7.7
3.1.29.02. Indolicidin analogue (cathelicidin-4) 1qx9 Bos taurus Secreted 1 0 6.6 ± 1.9 46 ± 15 -7.7
3.1.14.01. Tachykinin-4 2moc Homo sapiens Secreted 1 0 4.6 ± 0.6 75 ± 5 -7.7
3.1.10.01. Competence-stimulating peptide type 1 2a1c Streptococcus pneumoniae Secreted 1 0 4.8 ± 0.9 85 ± 20 -7.7
3.1.02.02. S5P linker peptide (570-611) of HERG K+ channel 1ujl Homo sapiens Eukaryo. plasma 1 0 4.6 ± 0.3 89 ± 7 -7.6
3.1.21.02. Mastoparan-L 1d7n Vespula lewisii Secreted 1 0 6.5 ± 1.7 82 ± 16 -7.5
3.1.13.01. Proadrenomedullin N-20 terminal peptide 2fly Homo sapiens Secreted 1 0 4.8 ± 4.0 88 ± 2 -7.5
3.1.29.03. Prophenin-1 analogues 2i1e Sus scrofa Secreted 1 0 5.2 ± 1.0 53 ± 7 -7.5
3.1.03.10. Lipid droplet anchoring peptide of CGI-58 5a4h Mus musculus Vesicle 1 0 3.9 ± 1.2 37 ± 7 -7.5
3.1.23.01. Meucin-24 2kfe Mesobuthus eupeus Secreted 1 0 4.3 ± 3.5 82 ± 2 -7.5
3.1.02.02. Potassium voltage-gated channel protein Shaker, peptide 378-397 1ho2 Drosophila melanogaster Eukaryo. plasma 1 0 3.9 ± 1.2 88 ± 16 -7.5
3.1.21.01. Papiliocin 2la2 Papilio xuthus Secreted 1 0 7.8 ± 2.0 62 ± 4 -7.4
3.1.05.07. Penetratin 1omq Designed proteins Undefined 1 0 3.2 ± 1.0 79 ± 7 -7.4
3.1.02.01. Fourth intracellular loop of CB1 cannabinoid receptor 2mz2 Designed proteins Eukaryo. plasma 1 0 6.3 ± 1.2 80 ± 6 -7.4
3.1.04.05. Lactotransferrin peptide (287-303) 2md1 Bos taurus Secreted 1 0 6.0 ± 1.0 71 ± 9 -7.3
3.1.02.01. Second intracellular loop (118-149) of alpha-2A adrenergic receptor 1hod Homo sapiens Eukaryo. plasma 1 0 3.9 ± 4.1 75 ± 3 -7.2
3.1.01.01. Varv peptide A/Kalata-B1 propeptide 1wn4 Viola odorata Secreted 1 0 6.4 ± 1.1 81 ± 14 -7.2
3.1.07.05. Nonstructural protein 2a, segment 1194-1221 2m0s Dengue virus Endoplasm. reticulum 1 0 7.4 ± 3.6 79 ± 1 -7.1
3.1.02.12. Juxtamembrane peptide of epidermal growth factor receptor 1z9i Homo sapiens Eukaryo. plasma 1 0 4.7 ± 1.6 78 ± 5 -7.1
3.1.06.01. Apolipoprotein A-I, peptide 190-209 1odq Homo sapiens Undefined 1 0 3.3 ± 0.7 87 ± 4 -7.1
3.1.31.01. Dermcidin, structure 1 2ksg Homo sapiens Secreted 1 0 4.7 ± 1.4 45 ± 6 -7.0
3.1.28.01. Dermaseptin-4 2dd6 Phyllomedusa sauvagei (Sauvage's leaf frog) Secreted 1 0 4.2 ± 1.6 76 ± 6 -7.0
3.1.11.01. Neuropeptide F 1k8v Moniezia expansa (Sheep tapeworm) Secreted 1 0 2.9 ± 1.1 68 ± 9 -7.0
3.1.28.01. Dermatistinctin K 2k9b Phyllomedusa distincta Secreted 1 0 4.6 ± 1.0 90 ± 10 -7.0
3.1.02.13. Regulatory domain of brain carnitine palmitoyltransferase 2m76 Homo sapiens Mitochon. outer 1 0 6.7 ± 1.0 88 ± 16 -6.9
3.1.02.10. Transmembrane emp24 domain-containing protein 10, peptide 207-219 1m23 Oryctolagus cuniculus Golgi 1 0 4.9 ± 3.2 66 ± 3 -6.9
3.1.07.01. Fusion peptide of E1 envelope glycoprotein (84-101) 2rsw Chikungunya virus Endosome 1 0 8.3 ± 0.6 57 ± 7 -6.9
3.1.07.01. Fusion peptide (524-539) of ebolavirus glycoprotein GP2 2rlj Zaire ebolavirus Viral 1 0 5.8 ± 1.8 84 ± 6 -6.8
3.1.11.02. Pituitary adenylate cyclase activating polypeptide (PACAP)-38 2d2p Homo sapiens Secreted 1 0 3.9 ± 4.0 90 ± 0 -6.8
3.1.07.03. Hemagglutinin, peptide 330-349, F9A 2jrd Influenza virus Viral 1 0 8.1 ± 4.0 71 ± 5 -6.8
3.1.14.01. Neurokinin B 1p9f Homo sapiens Secreted 1 0 5.8 ± 1.2 89 ± 18 -6.8
3.1.21.04. Oxyopinin-4a 2l3i Oxyopes takobius (Lynx spider) Secreted 1 0 6.2 ± 1.2 71 ± 10 -6.8
3.1.08.01. Ice-structuring protein SS-3 1y04 Myoxocephalus scorpius Secreted 1 1 4.2 ± 3.8 90 ± 5 -6.7
3.1.13.01. Adrenomedullin 2l7s Homo sapiens Secreted 1 0 2.6 ± 0.7 90 ± 5 -6.7
3.1.05.03. LAK160-P12 2l9a Designed proteins Undefined 1 0 4.9 ± 3.1 87 ± 1 -6.7
3.1.15.01. Curvacin-A 2a2b Lactobacillus curvatus Secreted 1 0 2.5 ± 1.3 34 ± 18 -6.7
3.1.11.02. Glucagon-like peptide 1, with extracellular GPCR domain 3iol Homo sapiens Secreted 2 0 2.8 ± 4.0 70 ± 1 -6.7
3.1.04.03. Viral protein R, peptide 50-82 1bde Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.8 ± 1.1 89 ± 24 -6.7
3.1.28.08. Ocellatin-LB1 5u9v Leptodactylus labyrinthicus Secreted 1 0 4.7 ± 1.4 76 ± 4 -6.6
3.1.11.02. Glucagon 1gcn Sus scrofa Secreted 1 0 5.3 ± 1.0 78 ± 12 -6.6
3.1.15.01. Leucocin A, linear analogue 2ljt Leuconostoc gelidum Secreted 1 0 4.2 ± 2.8 81 ± 1 -6.6
3.1.02.16. Peptide 211-263 of YscU protein 2ml9 Yersinia pseudotuberculosis Bact. Gram-neg inner 1 0 2.9 ± 1.8 82 ± 5 -6.6
3.1.01.02. Leader peptide of bacteriocin microcin B17 2mlp Escherichia coli Secreted 1 0 3.2 ± 3.6 84 ± 4 -6.6
3.1.02.08. High affinity copper uptake protein 1, peptide 156-179 2ls4 Homo sapiens Eukaryo. plasma 1 0 4.9 ± 0.7 82 ± 10 -6.5
3.1.11.02. Extendin-4, with extracellular domain of glucagon-like peptide-1 GPCR 3c59 Heloderma suspectum Secreted 2 0 1.9 ± 0.2 64 ± 0 -6.5
3.1.03.02. Serine/threonine-protein kinase TOR1, FATC domain 2kit Saccharomyces cerevisiae Vacuole 1 0 6.3 ± 1.0 87 ± 18 -6.4
3.1.25.01. Latarcin-2a (M-zodatoxin-Lt2a) 2g9p Lachesana tarabaevi (Spider) Secreted 1 0 8.5 ± 1.4 77 ± 9 -6.4
3.1.11.02. Glucagon 1kx6 Bos taurus Secreted 1 0 4.4 ± 2.0 70 ± 0 -6.4
3.1.21.01. Cecropin A (1-8) - magainin (1-12) hybrid 1d9j Hyalophora cecropia (Cecropia moth) Secreted 1 0 2.3 ± 0.9 90 ± 10 -6.4
3.1.11.06. Parathyroid hormone-related peptide, structure 1 1bzg Homo sapiens Secreted 1 0 6.4 ± 2.2 54 ± 18 -6.4
3.1.28.03. Maximin-4 2mhw Bombina maxima Secreted 1 0 4.4 ± 1.0 75 ± 3 -6.3
3.1.05.03. WYHRLSHLHSRLQD 5mxt Designed proteins Undefined 1 0 5.0 ± 0.8 77 ± 10 -6.3
3.1.04.09. Membrane-permeabilizing peptide (654-676) from hemocyanin 2n1c Litopenaeus vannamei (Whiteleg shrimp) Undefined 1 0 6.5 ± 1.3 90 ± 9 -6.3
3.1.15.05. Enterocin K1 5l82 Enterococcus faecium Secreted 1 0 7.0 ± 3.6 27 ± 6 -6.3
3.1.04.08. Truncated superoxide dismutase 1 2mp3 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 83 ± 0 -6.3
3.1.15.01. Leucocin A 1cw6 Leuconostoc gelidum Secreted 1 0 3.6 ± 1.1 90 ± 16 -6.2
3.1.30.01. Lactoferricin peptide (36-59) 5id5 Sus scrofa Secreted 1 0 7.4 ± 1.0 87 ± 9 -6.2
3.1.18.02. Phenol-soluble modulin beta-2 5kgz Staphylococcus aureus Secreted 1 0 6.2 ± 2.5 55 ± 7 -6.2
3.1.21.01. Cecropin (1-7)-melittin (2-9) hybrid 2jmy Designed proteins Undefined 1 0 6.5 ± 3.3 77 ± 7 -6.1
3.1.29.01. Retro KR-12 2nal Designed proteins Undefined 1 0 3.7 ± 0.5 83 ± 5 -6.1
3.1.11.02. Glucagon analog 1bh0 Homo sapiens Secreted 1 0 4.9 ± 4.2 78 ± 2 -6.1
3.1.11.01. Neuropeptide Y-pancreatic polypeptide hybrid 1tz4 Sus scrofa Secreted 1 0 5.1 ± 1.0 88 ± 8 -6.1
3.1.14.01. Neuropeptide gamma 2mce Oryctolagus cuniculus Secreted 1 0 8.4 ± 1.4 60 ± 10 -6.1
3.1.03.08. Lipid interacting helix (227-245) of digalactosyldiacylglycerol synthase 2l7c Arabidopsis thaliana Chloroplast outer 1 0 3.3 ± 3.6 88 ± 1 -6.0
3.1.11.02. Glucagon analog, lipidated 2m5p Homo sapiens Secreted 1 0 5.2 ± 0.6 85 ± 4 -6.0
3.1.15.05. LsbB 2mlu Lactococcus lactis Secreted 1 0 4.4 ± 4.1 89 ± 2 -6.0
3.1.11.02. Gastric inhibitory polypeptide, complex with N-terminal domain of GPCR 2qkh Homo sapiens Secreted 2 0 6.3 ± 3.2 64 ± 23 -5.9
3.1.07.04. Juxtamembrane peptide of hepatis C virus E1 glycoprotein (314-342) 2knu Hepatitis C virus Endosome 1 0 5.3 ± 0.9 82 ± 6 -5.9
3.1.11.01. Peptide YY 2dez Homo sapiens Secreted 1 0 4.0 ± 0.2 84 ± 2 -5.9
3.1.07.06. NS2 protease, segment 766-789 of polyprotein 2lzq Hepatitis GB virus Endoplasm. reticulum 1 0 3.2 ± 2.1 88 ± 1 -5.9
3.1.29.03. Prophenin-1 2i1d Sus scrofa Secreted 1 0 4.8 ± 1.9 70 ± 35 -5.9
3.1.20.01. alpha-conotoxin PNIB 1akg Conus pennaceus Secreted 1 0 4.2 ± 1.4 42 ± 19 -5.9
3.1.16.01. Lactococcin-G subunit alpha 2jpj Lactococcus lactis Secreted 1 0 5.8 ± 2.9 77 ± 3 -5.9
3.1.26.01. Piscidin 4 5h2s Oreochromis niloticus Secreted 1 0 4.6 ± 3.2 75 ± 2 -5.8
3.1.28.09. Pseudin-2, structure 1 2ncy Pseudis paradoxa Secreted 1 0 4.9 ± 3.0 77 ± 5 -5.8
3.1.14.01. Neuropeptide K 2b19 Homo sapiens Secreted 1 0 5.1 ± 4.3 46 ± 8 -5.7
3.1.02.07. Na(+)/H(+) antiporter, TMH IV, fusion construct 2m7w Saccharomyces cerevisiae Eukaryo. plasma 3 3 26.8 ± 0.1 0 ± 2 -5.7
3.1.11.02. Vasoactive intestinal peptide 2rrh Homo sapiens Secreted 1 0 4.1 ± 0.3 79 ± 9 -5.7
3.1.05.03. Lavracin 2n8d Designed proteins Undefined 1 0 5.1 ± 1.2 89 ± 13 -5.7
3.1.11.05. Parathyroid hormone 1et1 Homo sapiens Secreted 1 0 2.1 ± 0.5 85 ± 3 -5.6
3.1.06.01. Apolipoprotein E, peptide 281-304 1oef Homo sapiens Undefined 1 0 4.8 ± 0.9 88 ± 19 -5.5
3.1.24.01. Penaeidin-3a 1ueo Litopenaeus vannamei (Whiteleg shrimp) Secreted 1 0 1.3 ± 3.5 89 ± 2 -5.5
3.1.03.06. 12 kDa heat shock protein 4axp Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.5 ± 0.1 74 ± 0 -5.5
3.1.03.09. Peptide (2-11) of ADP-ribosylation factor 6, in aqueous solution 2bao Homo sapiens Eukaryo. plasma 1 0 8.0 ± 1.2 82 ± 8 -5.5
3.1.05.03. Peptide YW12 2o0s Designed proteins Bact. Gram-pos cell wall 1 0 3.4 ± 1.3 82 ± 5 -5.5
3.1.11.04. Orexin-A 1wso Homo sapiens Secreted 1 0 6.4 ± 1.7 72 ± 14 -5.5
3.1.28.04. Esculentin-1A, structure 2 5xdj Pelophylax esculentus Secreted 1 0 7.2 ± 1.2 76 ± 8 -5.4
3.1.11.02. Glucagon-like peptide-1 receptor agonists 2n08 Designed proteins Undefined 1 0 6.3 ± 1.3 45 ± 10 -5.4
3.1.12.01. Endothelin-1 1edn Homo sapiens Secreted 1 0 4.3 ± 1.2 71 ± 25 -5.4
3.1.11.01. Peptide YY 1ru5 Sus scrofa Secreted 1 0 5.1 ± 1.2 83 ± 3 -5.3
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, mutant 2 2m5f Zaire ebolavirus Viral 1 0 5.7 ± 1.7 29 ± 30 -5.2
3.1.21.07. Cupiennin-1a (M-ctenitoxin-Cs1a) 2k38 Cupiennius salei (Wandering spider) Secreted 1 0 8.1 ± 4.0 77 ± 9 -5.1
3.1.11.06. Parathyroid hormone-related peptide, structure 2 3ffd Homo sapiens Secreted 1 0 2.2 ± 1.5 89 ± 3 -5.1
3.1.15.03. Bacteriocin peptide plantaricin E (PlnE) 2jui Lactobacillus plantarum Secreted 1 0 4.3 ± 4.2 79 ± 4 -5.0
3.1.07.02. Juxtamembrane peptide (662-683) of protein gp160 4g6f Human immunodeficiency virus type 1 Endosome 1 0 4.9 ± 1.4 86 ± 0 -5.0
3.1.05.03. LAK160-P10 2l99 Designed proteins Undefined 1 0 3.9 ± 2.6 84 ± 0 -5.0
3.1.05.01. Antimicrobial peptide RP-1 2rlg Designed proteins Undefined 1 0 5.9 ± 4.2 75 ± 4 -5.0
3.1.07.02. Membrane proximal external helix of HIV-1 gp41 (656-683) 2m8o Human immunodeficiency virus type 1 Viral 1 0 6.0 ± 5.2 90 ± 4 -5.0
3.1.11.02. Extendin-4 1jrj Heloderma suspectum Secreted 1 0 1.7 ± 0.8 79 ± 8 -5.0
3.1.02.02. S4-S5 linker peptide (532-551) of HERG K+ channel 2le7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.4 69 ± 9 -5.0
3.1.03.04. Anchor helix of protein yopD (peptide 278-300) 1kdl Yersinia pseudotuberculosis Eukaryo. plasma 1 0 5.7 ± 0.8 86 ± 12 -5.0
3.1.14.01. Eledoisin 1mxq Eledone cirrhosa (Curled octopus) Secreted 1 0 2.9 ± 1.7 59 ± 19 -5.0
3.1.14.01. Neurokinin A 1n6t Gallus gallus Secreted 1 0 6.8 ± 1.2 60 ± 17 -4.9
3.1.30.01. Lactoferrin-based peptide, 21-67 1z6v Homo sapiens Secreted 1 0 1.7 ± 1.4 84 ± 3 -4.9
3.1.11.03. Motilin 1lbj Homo sapiens Secreted 1 0 8.6 ± 1.6 51 ± 18 -4.9
3.1.02.07. Sodium/hydrogen exchanger 1, TM helices 2kbv Homo sapiens Eukaryo. plasma 1 0 2.7 ± 6.9 74 ± 4 -4.9
3.1.20.01. Alpha4/6-conotoxin TxIC 2m3i Conus lividus Secreted 1 0 5.3 ± 1.0 77 ± 10 -4.9
3.1.05.03. Human platelet factor 4 based peptide, 56-70, modified 1djf Designed proteins Undefined 1 0 1.9 ± 1.4 87 ± 8 -4.9
3.1.20.01. alpha-conotoxin auIB 1dg2 Conus aulicus Secreted 1 0 5.1 ± 1.7 89 ± 16 -4.9
3.1.15.01. Enterocin-HF 2n4k Enterococcus faecium Secreted 1 0 4.8 ± 3.5 82 ± 4 -4.8
3.1.12.01. Endothelin-1 3cmh Rattus norvegicus Secreted 1 0 6.3 ± 3.9 72 ± 40 -4.8
3.1.20.01. Alpha-conotoxin BuIA 2i28 Conus bullatus (Bubble cone) Secreted 1 0 7.4 ± 2.2 68 ± 9 -4.6
3.1.30.01. Lactoferrin-based peptide, 39-49 2gmc Homo sapiens Secreted 1 0 3.9 ± 1.7 79 ± 13 -4.6
3.1.05.04. Distinctin 1xkm Designed proteins Undefined 2 0 3.9 ± 0.4 87 ± 2 -4.6
3.1.05.05. Anticoccidial peptide PW2 2jq2 Designed proteins Undefined 1 0 6.2 ± 2.3 67 ± 36 -4.5
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, wild type 2lcy Zaire ebolavirus Viral 1 0 3.5 ± 2.2 59 ± 9 -4.5
3.1.14.01. Kassinin 1myu Kassina senegalensis Secreted 1 0 3.4 ± 1.5 59 ± 16 -4.5
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, mutant 1 2mb1 Zaire ebolavirus Viral 1 0 3.8 ± 1.8 53 ± 34 -4.5
3.1.05.13. Cullin3-derived peptides 2myl Designed proteins Undefined 1 0 3.4 ± 1.2 82 ± 21 -4.4
3.1.15.01. Sakacin P 1ohm Lactobacillus sake Secreted 1 0 1.8 ± 1.1 90 ± 11 -4.4
3.1.20.01. Alpha-conotoxin PIA 1zlc Conus purpurascens (Purple cone) Secreted 1 0 2.6 ± 1.3 59 ± 16 -4.3
3.1.20.01. O2-contryphan-Vc2 5l34 Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.4 85 ± 8 -4.2
3.1.01.05. Proteinase inhibitor, vacuolar targeting peptide (372-397) 1vtp Nicotiana alata (Winged tobacco) Vacuole 1 0 3.5 ± 1.1 87 ± 4 -4.2
3.1.20.01. alpha-conotoxin MII 1mii Conus magus Secreted 1 0 2.7 ± 1.8 45 ± 19 -4.2
3.1.04.06. Amyloidogenic peptide (248-286) of prostatic acid phosphatase 2l3h Homo sapiens Eukaryo. plasma 1 0 4.5 ± 2.7 86 ± 0 -4.2
3.1.13.01. Islet amyloid polypeptide, peptide 38-74 2kj7 Rattus norvegicus Secreted 1 0 3.9 ± 4.3 90 ± 4 -4.2
3.1.12.01. Sarafotoxin-B 1srb Atractaspis engaddensis (Israeli burrowing asp) Secreted 1 0 4.9 ± 1.9 62 ± 10 -4.1
3.1.21.01. Cecropin-P1 2n92 Ascaris suum Secreted 1 0 1.6 ± 3.4 90 ± 0 -4.1
3.1.20.01. Conotoxin pc16a 2ler Conus pictus Secreted 1 0 4.0 ± 1.0 64 ± 7 -4.1
3.1.20.01. Conotoxin Ar1446 2m61 Conus araneosus Secreted 1 0 1.8 ± 0.8 82 ± 6 -4.0
3.1.05.03. VG16KRKP peptide, structure 2 2n63 Designed proteins Undefined 1 0 2.5 ± 0.3 57 ± 4 -4.0
3.1.21.06. Spinigerin 1zrv Pseudacanthotermes spiniger Secreted 1 0 2.1 ± 3.4 77 ± 5 -3.9
3.1.02.03. Juxtamembrane helix of ATP synthase subunit b 2khk Escherichia coli Bact. Gram-neg inner 1 0 1.9 ± 0.1 85 ± 3 -3.9
3.1.11.01. Pancreatic hormone 1ppt Meleagris gallopavo Secreted 1 0 3.5 ± 2.9 90 ± 27 -3.9
3.1.28.02. Neuromedin-B 1c98 Homo sapiens Secreted 1 0 4.3 ± 1.8 77 ± 11 -3.8
3.1.20.01. Alpha-conotoxin PIVA 1p1p Conus purpurascens (Purple cone) Secreted 1 0 2.4 ± 1.0 30 ± 11 -3.8
3.1.03.07. N-terminal peptide (24-58) of Disabled homolog 2 2lsw Homo sapiens Vesicle 1 0 2.1 ± 0.6 85 ± 5 -3.8
3.1.20.01. alpha-conotoxin PNI1 1pen Conus pennaceus Secreted 1 0 5.2 ± 1.7 27 ± 19 -3.8
3.1.02.09. Peptide (659-711) of platelet endothelial cell adhesion molecule 2ky5 Homo sapiens Eukaryo. plasma 1 0 1.0 ± 3.8 89 ± 3 -3.7
3.1.20.01. Alpha-conotoxin ImI 1e75 Conus imperialis (Imperial cone) Secreted 1 0 1.9 ± 0.9 80 ± 15 -3.7
3.1.02.14. Tumor-associated calcium signal transducer 2, peptide 304-322 2mae Homo sapiens Eukaryo. plasma 1 0 3.7 ± 3.0 82 ± 0 -3.7
3.1.20.01. Alpha-conotoxin OmIA 2gcz Conus omaria (Omaria cone) Secreted 1 0 3.0 ± 1.5 62 ± 11 -3.7
3.1.22.01. Antifungal peptide 2mp9 Cenchritis muricatus Secreted 1 0 1.2 ± 1.5 90 ± 26 -3.7
3.1.29.01. Cathelicidin-5 2ndc Bos taurus Secreted 1 0 2.1 ± 2.1 82 ± 17 -3.7
3.1.20.01. O2-contryphan-Vc1 2n24 Conus victoriae (Queen Victoria cone) Secreted 1 0 1.6 ± 1.0 89 ± 22 -3.6
3.1.04.02. Major prion protein, peptide 173-195 2iv5 Homo sapiens Eukaryo. plasma 1 0 5.3 ± 4.1 83 ± 17 -3.5
3.1.20.01. Rho-conotoxin TIA 1ien Conus tulipa (Fish-hunting cone snail) Secreted 1 0 3.4 ± 1.6 73 ± 7 -3.5
3.1.29.01. Cathelin-related peptide SC5 (SMAP-29) 1fry Ovis aries Secreted 1 0 1.1 ± 0.8 18 ± 9 -3.5
3.1.20.01. Alpha-conotoxin EIVA 1pqr Conus ermineus Secreted 1 0 2.5 ± 1.3 14 ± 14 -3.4
3.1.20.01. Alpha-conotoxin EI 1k64 Conus ermineus Secreted 1 0 3.6 ± 1.4 78 ± 19 -3.3
3.1.05.03. VG16KRKP peptide, structure 1 2mxh Designed proteins Undefined 1 0 2.5 ± 2.4 82 ± 11 -3.2
3.1.20.01. Alpha-conotoxin-like EpI 1a0m Conus episcopatus (Bishop's cone) Secreted 1 0 3.3 ± 1.2 58 ± 9 -3.2
3.1.11.03. Obestatin 2jsi Mus musculus Secreted 1 0 2.0 ± 3.3 85 ± 13 -3.1
3.1.28.02. Neuromedin-C 2n0h Homo sapiens Secreted 1 0 4.1 ± 1.6 82 ± 18 -3.1
3.1.34.01. Conantokin-R1-B 2mzm Conus rolani Secreted 1 0 1.9 ± 0.7 81 ± 8 -2.9
3.1.12.01. Sarafotoxin-I3 2lde Atractaspis microlepidota microlepidota Secreted 1 0 4.2 ± 3.6 86 ± 8 -2.8
3.1.11.02. Exendin-4-conotoxin chimera 2naw Designed proteins Secreted 1 0 4.3 ± 1.4 69 ± 8 -2.7
3.1.05.03. LAK160-P7 2l96 Designed proteins Undefined 1 0 1.4 ± 0.9 88 ± 5 -2.7
3.1.20.01. Alpha-conotoxin Vc1A 2h8s Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.8 59 ± 6 -2.5
3.1.20.01. Alpha-conotoxin S1 1qmw Conus striatus Secreted 1 0 2.8 ± 2.6 43 ± 17 -2.5
3.1.20.01. Alpha-conotoxin GID 1mtq Conus geographus (Geography cone) Secreted 1 0 1.3 ± 2.5 78 ± 28 -2.4
3.1.35.01. Cn-AMP1 peptide 2n0v Cocos nucifera Secreted 1 0 2.9 ± 1.3 73 ± 18 -2.3
3.1.20.01. Alpha-conotoxin GIA 1not Conus geographus (Geography cone) Secreted 1 0 1.6 ± 1.5 89 ± 20 -2.3
3.1.20.01. Alpha-conotoxin CnIA 1b45 Conus consors (Singed cone) Secreted 1 0 0.8 ± 0.8 80 ± 20 -2.1
3.1.12.01. Sarafotoxin-M 2ldf Atractaspis microlepidota microlepidota Secreted 1 0 2.3 ± 1.5 30 ± 35 -2.1
3.1.11.01. Pancreatic hormone 1v1d Bos taurus Secreted 1 0 1.2 ± 3.0 79 ± 32 -1.9