PDB ID or protein name

Peptides of nonregular structure superfamilies

3.4.01. Gramicidin S (1 family)
3.4.02. Lantibiotic peptides (class I bacteriocins) (6 families) 1.C.20 (TCDB)
3.4.03. Heat-stable enterotoxin (1 family)
3.4.04. Cyclic lipopeptide antibiotics (2 families)
3.4.05. Cyclosporin (1 family)
3.4.06. Conomarphin (1 family)
3.4.07. Designed nonregular peptides (2 families)
3.4.08. Neurotensin/neuromedin N (1 family) PF07421 (Pfam)
3.4.09. Catestatin (1 family) PF01271 (Pfam)
See list of these PDB codes

Peptides of nonregular structure (24 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
3.4.05.01. Cyclosporin 1cwa Tolypocladium inflatum Secreted 1 0 10.2 ± 2.5 82 ± 53 -7.2
3.4.02.03. Nisin-Lipid II complex in DMSO solution 1wco Lactococcus lactis Secreted 1 0 8.1 ± 1.0 90 ± 5 -8.0
3.4.02.05. Lichenicidin VK21 A1 2ktn Bacillus licheniformis Secreted 1 0 7.0 ± 1.5 77 ± 13 -5.9
3.4.08.01. Neurotensin 2oyv Homo sapiens Secreted 1 0 7.3 ± 2.6 67 ± 17 -5.3
3.4.03.01. Heat-stable enterotoxin ST-IA/ST-P 1etn Escherichia coli Secreted 1 0 3.0 ± 3.7 33 ± 39 -2.1
3.4.09.01. Granin 1n2y Bos taurus Secreted 1 0 1.9 ± 2.1 71 ± 16 -3.4
3.4.01.01. Gramicidin S 1tk2 Bacillus brevis Secreted 1 0 8.5 ± 1.7 86 ± 21 -8.6
3.4.04.01. Tsushimycin 1w3m Streptomyces pseudogriseolus Secreted 1 0 9.5 ± 2.1 54 ± 24 -8.6
3.4.09.01. Granin 1lv4 Homo sapiens Secreted 1 0 1.8 ± 0.4 81 ± 3 -6.8
3.4.02.01. Actagardine, structure in acetonitrile solution 1aj1 Actinoplanes liguriae Secreted 1 0 3.0 ± 1.1 90 ± 11 -5.7
3.4.04.01. Daptomycin, Ca-free 1t5m Streptomyces roseosporus Secreted 1 0 2.3 ± 1.3 33 ± 6 -7.9
3.4.02.06. Epilancin 15X 1w9n Staphylococcus epidermidis Secreted 1 0 2.9 ± 1.0 72 ± 7 -5.0
3.4.02.02. Mersacidin, crystal structure 1qow Bacillus sp. Secreted 3 0 3.2 ± 2.7 72 ± 31 -5.5
3.4.04.01. Daptomycin, Ca-free 1xt7 Streptomyces roseosporus Secreted 1 0 9.3 ± 3.9 10 ± 45 -6.4
3.4.04.02. Surfactin 2npv Bacillus subtilis Secreted 1 0 11.3 ± 2.1 55 ± 13 -11.3
3.4.02.02. Mersacidin, structure in methanol solution 1mqx Bacillus sp. Secreted 1 0 1.9 ± 1.3 87 ± 15 -2.9
3.4.04.01. Daptomycin, Ca-bound 1t5n Streptomyces roseosporus Secreted 1 0 8.6 ± 2.0 21 ± 24 -9.0
3.4.06.01. Conomarphin 2jqc Conus marmoreus Secreted 1 0 4.1 ± 1.1 89 ± 12 -7.4
3.4.02.02. Mersacidin, structure in DPC micelles 1mqy Bacillus sp. Secreted 1 0 5.3 ± 0.9 90 ± 12 -6.1
3.4.02.04. Cinnamycin 2dde Streptoverticillium griseoverticillatum Secreted 1 0 3.6 ± 1.9 30 ± 24 -5.4
3.4.07.02. Compstatin 1a1p Designed proteins Undefined 1 0 3.4 ± 1.9 72 ± 18 -5.6
3.4.02.02. Mersacidin, structure of lipid II bound peptide in DPC micelles 1mqz Bacillus sp. Secreted 1 0 4.2 ± 2.8 83 ± 15 -4.2
3.4.02.05. Lichenicidin VK21 A2 2kto Bacillus licheniformis Secreted 1 0 6.6 ± 4.2 75 ± 3 -6.9
3.4.07.01. Antimicrobial cationic cyclic hexapeptide 1qvl Designed proteins Undefined 1 0 4.2 ± 1.6 84 ± 15 -6.8