PDB ID or protein name

Alpha + Beta monotopic/peripheral superfamilies

2.4.001. FAD-linked reductases (1 family)
2.4.002. NTF2-like (1 family) CL0051 (Pfam)
2.4.003. Transcriptional factor tubby (1 family) PF01167 (Pfam)
2.4.004. DNase I-like (1 family)
2.4.005. Sterol carrier protein (2 families) CL0311 (Pfam)
2.4.006. Bet v1-like (5 families) CL0209 (Pfam)
2.4.007. PX domain (1 family) PF00787 (Pfam)
2.4.008. Ribonuclease-like (1 family)
2.4.009. Cytomegalovirus assemblin (1 family)
2.4.010. PreATP-grasp domain (1 family)
2.4.011. Plant thionin (1 family) 1.C.44 (TCDB) PF00321 (Pfam)
2.4.012. Liver-expressed antimicrobial peptide (1 family) PF07359 (Pfam)
2.4.013. OSBP-related proteins (1 family) PF01237 (Pfam)
2.4.014. Phospholipid acyltransferase (1 family) PF01553 (Pfam)
2.4.015. Negative factor (Nef) protein (1 family) PF00469 (Pfam)
2.4.016. Scorpion toxin-like knottin (14 families) CL0054 (Pfam)
2.4.017. Apolipoprotein of LDL particles (1 family) PF01347 (Pfam)
2.4.018. NTN hydrolase superfamily (1 family) CL0052 (Pfam)
2.4.019. GlnB-like superfamily (1 family) CL0089 (Pfam)
2.4.020. Peptidase clan CA (4 families) CL0125 (Pfam)
2.4.021. Peptidase MD (2 families) CL0170 (Pfam)
2.4.022. FAD binding domain (1 family) PF01565 (Pfam)
2.4.023. Heme NO and oxygen binding like (1 family) CL0210 (Pfam)
2.4.024. Enolase like TIM barrel (1 family) CL0256 (Pfam)
2.4.025. N-acetyltransferase like (1 family) CL0257 (Pfam)
2.4.026. HIT superfamily (1 family) CL0265 (Pfam)
2.4.027. AIG2/ChaC-like superfamily (1 family) CL0278 (Pfam)
2.4.028. DAP epimerase superfamily (1 family) CL0288 (Pfam)
2.4.029. Superantigen toxins (1 family) CL0386 (Pfam)
2.4.030. TRAF domain-like superfamily (1 family) CL0389 (Pfam)
2.4.031. Fibrinogen (1 family) CL0422 (Pfam)
2.4.032. Acid phosphatase/Vanadium-dependent haloperoxidase (1 family) CL0525 (Pfam)
2.4.033. PGBD superfamily (2 families) CL0244 (Pfam)
2.4.034. Type III antifreeze protein (1 family) PF08666 (Pfam)
2.4.035. Catalase (1 family) PF00199 (Pfam)
2.4.036. Transforming growth factor (TGF)-beta (1 family) PF00688 (Pfam)
2.4.037. Monalysin (1 family)
2.4.038. PRELI/MSF1 (1 family) PF04707 (Pfam)
2.4.039. Bacterial sugar transferase (1 family) PF02397 (Pfam)
2.4.040. IpaB/EvcA family (1 family) PF03278 (Pfam)
2.4.041. Hepatitis C virus non-structural protein NS2 (1 family) PF01538 (Pfam)
2.4.042. Bactericidal permeability increasing protein family (1 family) 1.C.40 (TCDB) PF01273 (Pfam)
2.4.043. OmpA (1 family) PF00691 (Pfam)
2.4.044. Filovirus protein VP24 (1 family) PF06389 (Pfam)
2.4.049. Inositol-pentakisphosphate 2-kinase (1 family) PF06090 (Pfam)
2.4.050. Vesiculovirus matrix protein (1 family) PF06326 (Pfam)
2.4.051. Heme-binding protein A (1 family) PF06438 (Pfam)
2.4.052. Spondin (1 family) PF06468 (Pfam)
2.4.053. Resistin (1 family) PF06954 (Pfam)
See list of these PDB codes

Alpha + Beta monotopic/peripheral (248 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.4.16.03. Potassium channel toxin alpha-KTx 3.1 3odv Androctonus mauretanicus mauretanicus (Scorpion) Secreted 1 0 2.6 ± 0.9 84 ± 5 -5.1
2.4.16.04. Flower-specific gamma-thionin-like protein 4uj0 Solanum lycopersicum Secreted 1 0 2.6 ± 0.9 19 ± 5 -4.8
2.4.25.01. Uncharacterized N-acetyltransferase SSO0209 2x7b Sulfolobus solfataricus Undefined 1 0 3.9 ± 1.5 49 ± 6 -7.6
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1uw5 Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.5 18 ± 16 -5.4
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 2 4axd Arabidopsis thaliana Eukaryo. plasma 1 0 1.5 ± 0.1 88 ± 4 -4.0
2.4.04.01. Sphingomyelin phosphodiesterase 3 5uvg Homo sapiens Golgi 1 0 2.9 ± 1.6 59 ± 13 -5.1
2.4.16.03. Charybdotoxin 2crd Leiurus quinquestriatus hebraeus Secreted 1 0 1.1 ± 1.5 86 ± 15 -3.2
2.4.16.01. Alpha-toxin Cn12 1pe4 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.1 ± 2.3 17 ± 13 -3.1
2.4.42.01. Cholesteryl ester transfer protein 2obd Homo sapiens Secreted 1 0 7.4 ± 2.9 26 ± 6 -7.0
2.4.34.01. Ice-structuring protein RD1 1ucs Lycodichthys dearborni Secreted 1 0 2.2 ± 1.0 67 ± 9 -5.5
2.4.15.01. Protein Nef, complex with T-cell surface glycoprotein CD3 zeta chain 3ik5 Simian immunodeficiency virus Eukaryo. plasma 2 0 3.1 ± 0.5 78 ± 7 -4.5
2.4.06.01. First StARkin domain of Lam2 5yqi Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.9 ± 1.6 30 ± 8 -4.1
2.4.07.01. Sorting nexin-23 (Kinesin-like protein KIF16B) 2v14 Homo sapiens Endosome 1 0 3.3 ± 3.0 72 ± 14 -5.4
2.4.11.01. Viscotoxin A3 1okh Viscum album Secreted 1 0 4.6 ± 1.3 32 ± 19 -4.9
2.4.16.04. Defensin-like protein 1 1gpt Hordeum vulgare Secreted 1 0 3.1 ± 1.6 28 ± 18 -2.0
2.4.51.01. Heme acquisition protein HasA, apoprotein 4jes Yersinia pestis Secreted 1 0 5.2 ± 0.3 40 ± 2 -9.6
2.4.34.01. Type III antifreeze protein NFE6 5xqp Zoarces elongatus Secreted 1 0 4.0 ± 2.2 59 ± 10 -4.9
2.4.40.01. IpgB2 protein 3lxr Shigella flexneri Bact. Gram-neg inner 2 0 2.7 ± 0.4 75 ± 2 -6.7
2.4.30.01. TNF receptor-associated factor 2 1d01 Homo sapiens Eukaryo. plasma 3 0 3.5 ± 0.0 90 ± 0 -5.7
2.4.13.01. Oxysterol-binding protein homolog 4 (KES1), N-terminal helix removed 1zi7 Saccharomyces cerevisiae Golgi 1 0 2.5 ± 0.5 75 ± 8 -6.9
2.4.06.01. Steroidogenic acute regulatory protein, mitochondrial 3p0l Homo sapiens Mitochon. outer 1 0 3.0 ± 1.3 76 ± 10 -4.7
2.4.16.01. Alpha-mammal toxin AaH2 1aho Androctonus australis (Sahara scorpion) Secreted 1 0 1.7 ± 1.0 64 ± 17 -3.4
2.4.16.08. Hydramacin-1 2k35 Hydra vulgaris Secreted 1 0 2.0 ± 0.2 87 ± 2 -4.3
2.4.29.01. Enterotoxin type A 1dyq Staphylococcus aureus Secreted 1 0 3.9 ± 0.5 82 ± 6 -6.8
2.4.16.04. Defensin-like protein 32 2mz0 Arabidopsis thaliana Secreted 1 0 2.6 ± 1.4 19 ± 8 -3.4
2.4.35.01. Catalase-related protein 3e4w Mycobacterium paratuberculosis Undefined 2 0 9.6 ± 1.3 49 ± 6 -13.4
2.4.03.01. Tubby protein, ligand-bound 1i7e Mus musculus Eukaryo. plasma 1 0 3.8 ± 1.9 75 ± 13 -4.7
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 3 4axc Arabidopsis thaliana Eukaryo. plasma 1 0 3.2 ± 2.3 68 ± 15 -4.5
2.4.05.01. Sterol carrier protein 2 like domain of multifunctional enzyme type 2 1ikt Homo sapiens Peroxisome 1 0 3.5 ± 1.2 75 ± 17 -4.0
2.4.16.03. Toxin I5a 1sis Buthus eupeus Secreted 1 0 3.1 ± 1.4 74 ± 16 -4.4
2.4.16.01. Beta-insect depressant toxin LqhIT2 2i61 Leiurus quinquestriatus hebraeus Secreted 1 0 4.3 ± 1.6 80 ± 21 -3.7
2.4.16.05. Eurocin 2lt8 Eurotium amstelodami Secreted 1 0 5.3 ± 1.3 84 ± 12 -5.5
2.4.34.01. Ice-structuring protein 4ur4 Zoarces viviparus Secreted 1 0 3.2 ± 4.1 68 ± 2 -5.8
2.4.15.01. Protein Nef (HIV HV1LW) 2nef Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 6.3 ± 1.4 73 ± 3 -7.9
2.4.06.01. Second StARkin domain of Lam2 5ys0 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 4.4 ± 1.6 52 ± 4 -5.6
2.4.07.01. Nischarin 3p0c Homo sapiens Endosome 1 0 4.1 ± 0.5 82 ± 13 -7.0
2.4.11.01. Viscotoxin B 1jmp Viscum album Secreted 1 0 1.2 ± 1.4 52 ± 13 -3.2
2.4.16.04. Defensin NaD1 1mr4 Nicotiana tabacum Secreted 1 0 4.2 ± 1.8 59 ± 11 -3.0
2.4.42.01. Bactericidal permeability-increasing protein 1bp1 Homo sapiens Secreted 1 0 1.5 ± 2.4 51 ± 17 -4.3
2.4.20.01. Cathepsin F 1m6d Homo sapiens Lysosome 1 0 4.3 ± 0.8 80 ± 3 -11.7
2.4.14.01. 1-acyl-sn-glycerol-3-phosphate acyltransferase 5kym Thermotoga maritima Bact. Gram-neg inner 1 0 20.2 ± 1.0 28 ± 2 -32.3
2.4.19.01. Protein CutA 1osc Rattus norvegicus Eukaryo. plasma 3 0 1.3 ± 0.3 90 ± 1 -5.5
2.4.06.01. START domain of collagen type IV alpha-3-binding protein 2e3q Homo sapiens Golgi 1 0 4.3 ± 2.0 41 ± 17 -3.7
2.4.16.02. Drosomycin 1myn Drosophila melanogaster Secreted 1 0 4.6 ± 1.2 10 ± 17 -6.0
2.4.16.01. Alpha-insect toxin Lqq3 1lqq Leiurus quinquestriatus quinquestriatus Secreted 1 0 0.8 ± 1.0 80 ± 6 -3.3
2.4.16.02. Nasonin 2koz Nasonia vitripennis (Parasitic wasp) Secreted 1 0 2.9 ± 0.9 68 ± 7 -4.6
2.4.53.01. Resistin 1rfx Mus musculus Secreted 3 0 3.4 ± 1.2 10 ± 6 -8.7
2.4.16.01. Tau-theraphotoxin-Hs1a 2n9z Haplopelma schmidti Secreted 1 0 6.1 ± 1.3 68 ± 10 -5.6
2.4.23.01. Methyl-accepting chemotaxis protein 3eee Thermoanaerobacter tengcongensis Undefined 1 0 3.2 ± 0.9 81 ± 4 -5.9
2.4.03.01. Tubby protein, ligand-free 1c8z Mus musculus Eukaryo. plasma 1 0 2.8 ± 0.9 89 ± 13 -5.8
2.4.38.01. Ups1 transporter-Mdm35 complex, structure 1 4xiz Saccharomyces cerevisiae Mitochon. inner 2 0 2.0 ± 1.7 19 ± 13 -4.1
2.4.07.01. PX domain of NADH oxidase (p40phox), ligand-bound 1h6h Homo sapiens Endosome 1 0 3.9 ± 2.0 55 ± 14 -6.0
2.4.16.02. Defensin ARD1 1ozz Archaeoprepona demophon Secreted 1 0 4.9 ± 1.7 31 ± 17 -7.1
2.4.16.04. Defensin-like protein 195 1jxc Arabidopsis thaliana Secreted 1 0 4.0 ± 1.5 21 ± 20 -3.9
2.4.42.01. Latherin 3zpm Equus caballus Secreted 1 0 6.0 ± 0.4 75 ± 1 -8.0
2.4.16.04. Defensin NsD7, dimer 5vyp Nicotiana suaveolens Secreted 2 0 5.4 ± 0.8 87 ± 7 -7.1
2.4.15.01. Protein Nef, N-terminal helix (HIV HV1B1) 1zec Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.6 ± 4.1 89 ± 2 -6.8
2.4.06.01. Second StARkin domain of Lam2, dimer 5yqq Saccharomyces cerevisiae Endoplasm. reticulum 2 0 5.8 ± 1.6 88 ± 5 -7.7
2.4.04.01. Inositol polyphosphate 5-phosphatase OCRL-1 4cmn Homo sapiens Endosome 1 0 6.7 ± 1.6 83 ± 2 -9.2
2.4.11.01. Viscotoxin A2 1jmn Viscum album Secreted 1 0 2.3 ± 0.3 63 ± 8 -3.3
2.4.16.04. Defensin 3psm Pachyrhizus erosus Secreted 1 0 4.1 ± 1.8 32 ± 8 -5.4
2.4.16.02. Lucifensin 2lld Lucilia sericata Secreted 1 0 1.1 ± 1.7 11 ± 12 -3.0
2.4.18.01. Phospholipase B-like protein 3fgr Mus musculus Lysosome 2 0 6.5 ± 2.4 79 ± 8 -5.3
2.4.39.01. N,N-diacetylbacilliosaminyl-1-phosphate transferase PglC 5w7l Campylobacter concisus Bact. Gram-neg inner 1 0 14.5 ± 1.4 90 ± 1 -38.6
2.4.04.01. Type II inositol-1,4,5-trisphosphate 5-phosphatase 3n9v Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.4 63 ± 6 -6.0
2.4.06.01. STAR-related lipid transfer protein 11, apoprotein (open state) 2e3m Homo sapiens Golgi 1 0 3.4 ± 1.1 44 ± 12 -6.1
2.4.16.01. Toxin CsEv3 2sn3 Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.3 74 ± 17 -5.5
2.4.16.01. Beta-toxin CsEI 1b3c Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.9 ± 1.2 70 ± 7 -3.9
2.4.16.03. Chlorotoxin 6atw Leiurus quinquestriatus quinquestriatus Secreted 1 0 2.6 ± 2.0 58 ± 6 -5.4
2.4.53.01. Resistin, different conformation 1rgx Mus musculus Secreted 3 0 8.2 ± 1.2 12 ± 6 -12.1
2.4.16.04. Defensin-like protein 2 2n2r Raphanus sativus Secreted 1 0 2.5 ± 1.7 31 ± 24 -4.2
2.4.26.01. Putative uncharacterized protein 3nrd Rhizobium meliloti Undefined 2 0 5.8 ± 0.9 86 ± 3 -13.7
2.4.06.02. Phosphatidylinositol transfer protein beta isoform 2a1l Rattus norvegicus Eukaryo. plasma 1 0 4.7 ± 1.7 36 ± 17 -4.3
2.4.38.01. Ups1 transporter-Mdm35 complex, structure 2 4ytx Saccharomyces cerevisiae Mitochon. inner 2 0 5.4 ± 1.0 78 ± 0 -6.3
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-bound 1o7k Homo sapiens Endosome 1 0 15.2 ± 1.7 60 ± 15 -18.4
2.4.16.02. Sapecin 1l4v Sarcophaga peregrina Secreted 1 0 5.4 ± 1.5 84 ± 18 -5.1
2.4.16.01. Toxin BmKaIT1 1omy Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.0 ± 1.3 83 ± 10 -3.8
2.4.16.04. Flower-specific defensin D1, dimer 4cqk Nicotiana alata (Winged tobacco) Secreted 2 0 4.8 ± 2.4 88 ± 6 -7.1
2.4.16.03. Toxin SsTx 5x0s Scolopendra subspinipes Secreted 1 0 3.6 ± 1.2 56 ± 4 -7.4
2.4.15.01. Protein Nef 1avv Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.0 ± 1.5 75 ± 13 -3.4
2.4.06.01. First StARkin domain of Lam4 5yqj Saccharomyces cerevisiae Endoplasm. reticulum 1 0 9.3 ± 1.4 26 ± 8 -5.2
2.4.07.01. PX domain of sorting nexin-10 4on3 Homo sapiens Endosome 1 0 5.2 ± 1.6 69 ± 5 -7.7
2.4.04.01. Sphingomyelinase C 2ddt Bacillus cereus Secreted 1 0 4.1 ± 1.1 59 ± 8 -7.6
2.4.16.04. Defensin 1ti5 Vigna radiata (Mung bean) Secreted 1 0 1.9 ± 2.4 62 ± 16 -3.0
2.4.16.12. Actinomycesin 2ru0 Actinomyces sp. Secreted 1 0 3.5 ± 0.7 83 ± 7 -4.1
2.4.20.03. Protease NSP1 3ifu Porcine reproductive and respiratory syndrome virus Undefined 2 0 5.4 ± 1.2 89 ± 15 -9.8
2.4.43.01. Cell wall anchor protein of the T6SS system 4b62 Pseudomonas aeruginosa Bact. Gram-neg outer 1 0 2.8 ± 2.5 46 ± 36 -4.6
2.4.31.01. Ficolin-1 2wnp Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.8 65 ± 2 -5.3
2.4.07.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Homo sapiens Golgi 1 0 2.5 ± 1.3 56 ± 16 -4.8
2.4.16.01. Neurotoxin 2 1jza Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.7 68 ± 15 -5.6
2.4.16.01. Toxin CsEv1 1vna Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.9 ± 1.0 65 ± 10 -7.8
2.4.16.03. Potassium channel toxin gamma-KTx 1.1 1ne5 Centruroides noxius (Mexican scorpion) Secreted 1 0 3.9 ± 1.0 62 ± 2 -5.2
2.4.21.02. L-alanyl-D-glutamate peptidase 2vo9 Listeria phage A500 Secreted 1 0 3.1 ± 1.0 48 ± 4 -5.2
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 2 5iqw Pseudomonas aeruginosa Secreted 1 0 1.5 ± 0.2 24 ± 5 -4.8
2.4.06.04. STAR-related bacterial protein 3ggn Deinococcus radiodurans Undefined 1 0 5.2 ± 1.6 53 ± 8 -4.1
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1kcm Mus musculus Eukaryo. plasma 1 0 5.3 ± 1.4 59 ± 5 -11.0
2.4.06.01. Acyl-coenzyme A thioesterase 11 3fo5 Homo sapiens Endoplasm. reticulum 1 0 2.3 ± 1.4 57 ± 7 -3.9
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens Endosome 1 0 2.4 ± 1.6 88 ± 12 -4.6
2.4.16.04. Defensin-like protein 1 1ayj Raphanus sativus Secreted 1 0 11.0 ± 1.9 39 ± 19 -7.4
2.4.16.01. Toxin Bmka2 2kbj Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.1 ± 1.5 64 ± 15 -3.6
2.4.16.04. Flower-specific defensin D1, monomer 4ab0 Nicotiana alata (Winged tobacco) Secreted 1 0 3.5 ± 1.2 55 ± 13 -4.3
2.4.16.03. Potassium channel toxin alpha-KTx 4.2 6atl Tityus serrulatus Secreted 1 0 2.6 ± 1.6 66 ± 16 -3.4
2.4.15.01. Protein Nef (HIV 9HIV1) 2xi1 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 4.3 ± 0.6 57 ± 5 -5.0
2.4.01.01. Cholesterol oxidase 1coy Brevibacterium sterolicum Bact. Gram-pos plas. 1 0 4.4 ± 1.1 43 ± 10 -6.8
2.4.07.01. PX domain of vacuolar morphogenesis protein VAM7 1kmd Saccharomyces cerevisiae Vacuole 1 0 3.4 ± 1.2 76 ± 8 -7.8
2.4.16.05. Micasin 2lr5 Arthroderma otae Secreted 1 0 8.3 ± 0.6 58 ± 6 -7.8
2.4.16.04. Floral defensin-like protein 1 1n4n Petunia hybrida Secreted 1 0 1.8 ± 0.8 6 ± 9 -3.8
2.4.16.02. Coprisin 2ln4 Copris tripartitus Secreted 1 0 4.5 ± 0.6 42 ± 4 -5.3
2.4.20.01. Cysteine protease 3ois Xylella fastidiosa Undefined 1 0 3.2 ± 0.2 80 ± 4 -6.4
2.4.35.01. 8R-Lipoxygenase, N-terminal domain 1u5u Plexaura homomalla Eukaryo. plasma 1 0 3.1 ± 0.3 72 ± 3 -10.4
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 1 2xar Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 1.6 69 ± 7 -6.1
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 2 1zhy Saccharomyces cerevisiae Golgi 1 0 0.9 ± 0.4 87 ± 4 -4.7
2.4.16.01. Beta-mammal toxin Cn2 2yc1 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.8 ± 1.1 68 ± 9 -3.8
2.4.16.01. Alpha-insect toxin LqhaIT 2yeo Leiurus quinquestriatus hebraeus Secreted 1 0 3.5 ± 0.8 43 ± 13 -5.9
2.4.16.09. S-locus pollen protein 1ugl Brassica campestris (Field mustard) Secreted 1 0 1.3 ± 0.6 51 ± 5 -3.4
2.4.32.01. Vanadium chloroperoxidase 3bb0 Curvularia inaequalis Secreted 1 0 3.8 ± 0.8 52 ± 6 -5.3
2.4.51.01. Heme acquisition protein HasA 4xzd Yersinia pseudotuberculosis Secreted 1 0 3.5 ± 0.4 25 ± 2 -5.9
2.4.06.04. STAR-related bacterial protein 1t17 Caulobacter crescentus Undefined 1 0 3.4 ± 0.7 63 ± 2 -8.1
2.4.07.01. PX domain of C2alpha-PI3 kinase 2ar5 Homo sapiens Eukaryo. plasma 1 0 5.6 ± 0.9 83 ± 17 -3.7
2.4.41.01. Hepatitis C virus non-structural protein NS2 (955-1026) 2hd0 Hepatitis C virus Endoplasm. reticulum 2 0 6.7 ± 0.6 85 ± 0 -11.8
2.4.07.01. PX domain of sorting nexin GRD19, ligand-bound 1ocu Saccharomyces cerevisiae Endosome 2 0 15.3 ± 0.8 88 ± 6 -34.9
2.4.16.04. Defensin 1 1jkz Pisum sativum Secreted 1 0 3.5 ± 1.6 8 ± 19 -5.4
2.4.16.02. Defensin MGD-1 1fjn Mytilus galloprovincialis (Mediterranean mussel) Secreted 1 0 1.5 ± 1.4 43 ± 12 -3.0
2.4.51.01. Heme acquisition protein HasA, alternative position of heme 3mol Pseudomonas aeruginosa Secreted 1 0 2.9 ± 0.6 40 ± 5 -5.8
2.4.16.03. Potassium channel toxin gamma-KTx 2.2 6au7 Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.2 ± 1.6 78 ± 11 -3.4
2.4.05.01. Uncharacterized protein 3cnu Archaeoglobus fulgidus Archaebac. 1 0 7.6 ± 1.7 69 ± 20 -7.0
2.4.15.01. Protein Nef, complex with tyrosine-protein kinase SH3 domain (HIV HV1A2) 3rbb Human immunodeficiency virus type 1 Eukaryo. plasma 2 0 2.4 ± 1.1 84 ± 6 -4.2
2.4.02.01. Epoxide Hydrolase 2bng Mycobacterium tuberculosis Bact. Gram-pos plas. 2 0 8.2 ± 0.6 88 ± 4 -24.0
2.4.13.01. Protein Osh1 5h2d Kluyveromyces lactis Vacuole 1 0 0.4 ± 2.4 71 ± 26 -2.7
2.4.16.01. Beta-insect excitatory toxin BmKIT1 1wwn Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.2 ± 1.1 72 ± 6 -4.4
2.4.16.04. Defensin 2 (PDF1) 2gl1 Vigna radiata (Mung bean) Secreted 1 0 2.8 ± 0.6 6 ± 4 -5.7
2.4.16.04. Defensin Lc-def 2lj7 Lens culinaris Secreted 1 0 2.2 ± 0.9 22 ± 10 -3.9
2.4.29.01. Superantigen-like protein 3r2t Staphylococcus aureus Undefined 1 0 4.2 ± 0.0 79 ± 1 -6.2
2.4.05.01. Sterol carrier protein 2 1c44 Oryctolagus cuniculus Eukaryo. plasma 1 0 3.7 ± 1.2 74 ± 17 -4.8
2.4.20.04. Group XVI phospholipase A1/A2 2kyt Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.5 62 ± 18 -4.9
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 3 4jch Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.2 88 ± 1 -6.0
2.4.16.01. Alpha-like neurotoxin BmK-I 1djt Buthus martensii Secreted 2 0 3.8 ± 0.9 90 ± 15 -6.9
2.4.16.01. Beta-toxin Cn5 2kja Centruroides noxius (Mexican scorpion) Secreted 1 0 4.1 ± 1.1 73 ± 6 -7.0
2.4.16.10. Toxin MIT1 (Black mamba intestinal toxin 1) 1imt Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 4.8 ± 0.7 70 ± 3 -9.1
2.4.52.01. Spondin-2 3d34 Homo sapiens Secreted 1 0 6.3 ± 0.7 35 ± 5 -10.4
2.4.51.01. Heme acquisition protein HasA, dimer 4y4s Yersinia pseudotuberculosis Secreted 1 0 1.8 ± 1.1 83 ± 9 -4.2
2.4.11.01. Crambin, enantiomer 3ue7 Designed proteins Undefined 1 0 3.4 ± 1.7 89 ± 13 -4.6
2.4.06.01. StAR-related lipid transfer protein 5 2r55 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 47 ± 19 -4.8
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 1 4b2z Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.3 ± 1.3 86 ± 6 -4.6
2.4.07.01. PX domain of sorting nexin GRD19, ligand-free 1ocs Saccharomyces cerevisiae Endosome 1 0 2.5 ± 1.1 88 ± 11 -5.4
2.4.04.01. Sphingomyelinase C 1zwx Listeria ivanovii Secreted 1 0 6.2 ± 0.5 55 ± 1 -10.1
2.4.16.02. Defensin 2nz3 Anopheles gambiae (African malaria mosquito) Secreted 1 0 6.7 ± 1.3 84 ± 10 -7.4
2.4.51.01. Heme acquisition protein HasA 3ell Pseudomonas aeruginosa Secreted 1 0 3.3 ± 0.4 18 ± 8 -5.5
2.4.16.03. Insectotoxin-I1 6ava Mesobuthus eupeus Secreted 1 0 1.8 ± 1.6 60 ± 7 -3.8
2.4.06.05. Thermoacidophile-specific fatty acid carrier 3w9k Sulfolobus tokodaii Archaebac. 1 0 2.7 ± 1.4 47 ± 4 -7.1
2.4.07.01. NADPH oxidase organizer 1, PX domain 2l73 Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.9 72 ± 13 -5.1
2.4.01.01. Cholesterol oxidase 1b4v Streptomyces sp. Bact. Gram-pos plas. 1 0 5.4 ± 0.6 39 ± 4 -8.4
2.4.50.01. Matrix protein, Indiana virus 1lg7 Vesicular stomatitis virus Viral 1 0 2.7 ± 0.4 82 ± 2 -7.3
2.4.05.02. SDS hydrolase SdsA1 2cfu Pseudomonas aeruginosa Secreted 1 0 6.0 ± 2.5 70 ± 4 -7.0
2.4.16.06. Mytilin-B 2eem Mytilus edulis (Blue mussel) Secreted 1 0 3.6 ± 1.4 76 ± 8 -3.2
2.4.16.08. Theromacin 2ln8 Hirudo medicinalis Secreted 1 0 3.7 ± 0.2 72 ± 3 -6.4
2.4.28.01. Phenazine biosynthesis protein PhzF 1s7j Enterococcus faecalis Undefined 1 0 1.8 ± 0.7 77 ± 2 -4.3
2.4.06.01. Cholesterol-regulated Start protein 4 (StarD4) 5brl Mus musculus Eukaryo. plasma 1 0 3.7 ± 1.1 67 ± 13 -3.7
2.4.07.01. Sorting nexin-11, conformation 1 4ikb Homo sapiens Eukaryo. plasma 1 0 5.2 ± 2.7 61 ± 8 -6.1
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 4 3spw Saccharomyces cerevisiae Golgi 1 0 7.3 ± 1.1 60 ± 9 -4.5
2.4.16.01. Neurotoxin 1dq7 Buthus tamulus Secreted 1 0 5.9 ± 1.8 88 ± 18 -8.1
2.4.16.01. Alpha-toxin CsE5 1nra Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.3 ± 1.2 89 ± 22 -4.3
2.4.16.04. Defensin-like protein 1brz Pentadiplandra brazzeana Secreted 1 0 1.2 ± 1.2 83 ± 10 -3.6
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 1 3mok Pseudomonas aeruginosa Secreted 1 0 4.5 ± 0.7 37 ± 7 -6.7
2.4.16.04. Defensin NsD7 5kk4 Nicotiana tabacum Secreted 2 0 3.5 ± 0.7 80 ± 4 -5.6
2.4.08.01. Eosinophil cationic protein 1h1h Homo sapiens Granule 1 0 3.5 ± 1.0 88 ± 6 -7.3
2.4.05.01. Uncharacterized protein 3bkr Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.4 ± 6.2 50 ± 73 -1.2
2.4.13.01. Oxysterol-binding protein homolog 3 4ic4 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 4.3 ± 0.9 86 ± 29 -5.9
2.4.06.01. Lipid transport protein Mln64 (StARD3) 1em2 Homo sapiens Endosome 1 0 2.0 ± 1.1 82 ± 12 -5.0
2.4.11.01. Crambin 1ejg Crambe abyssinica Secreted 1 0 4.0 ± 1.7 79 ± 15 -7.0
2.4.16.02. Defensin 2b68 Crassostrea gigas (Pacific oyster) Secreted 1 0 5.8 ± 1.7 28 ± 20 -4.0
2.4.51.01. Heme acquisition protein HasA, apoprotein 1ybj Serratia marcescens Secreted 1 0 2.8 ± 2.4 33 ± 9 -3.9
2.4.16.03. Potassium channel toxin alpha-KTx 6.9 6avd Opistophthalmus carinatus Secreted 1 0 1.5 ± 1.6 57 ± 7 -2.9
2.4.05.01. Sterol carrier protein 2 2cx7 Thermus thermophilus Bact. Gram-neg inner 1 0 4.7 ± 1.3 73 ± 13 -6.9
2.4.03.01. Tubby protein homolog 1s31 Homo sapiens Eukaryo. plasma 1 0 6.8 ± 1.0 71 ± 2 -7.6
2.4.20.02. Arylamine N-acetyltransferase 1w5r Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 2.6 ± 0.5 82 ± 6 -6.2
2.4.50.01. Matrix protein, New Jersey virus 2w2r Vesicular stomatitis virus Viral 1 0 4.1 ± 0.1 57 ± 1 -10.4
2.4.11.01. Beta-hordothionin 1wuw Hordeum vulgare Secreted 1 0 3.6 ± 1.1 55 ± 15 -5.4
2.4.12.01. Liver-expressed antimicrobial peptide 2 2l1q Homo sapiens Secreted 1 0 5.3 ± 1.4 56 ± 11 -2.7
2.4.34.01. Type III antifreeze protein nfeAFP11 2lx2 Zoarces elongatus Secreted 1 0 5.3 ± 1.0 53 ± 5 -7.0
2.4.27.01. Gamma-glutamylaminecyclotransferase 1vkb Mus musculus Undefined 1 0 2.3 ± 0.7 72 ± 4 -4.8
2.4.06.01. Phosphatidylcholine transfer protein 1ln1 Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 53 ± 16 -4.8
2.4.07.01. Sorting nexin-11, conformation 2 4ikd Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.2 58 ± 4 -5.3
2.4.25.01. N-alpha-acetyltransferase 60, structure 1 5hgz Homo sapiens Golgi 1 0 5.7 ± 1.1 41 ± 7 -8.5
2.4.16.01. Toxin VII 1npi Tityus serrulatus Secreted 1 0 4.6 ± 1.5 52 ± 16 -6.7
2.4.16.01. Alpha-mammal toxin BmK-M8 1snb Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.4 ± 2.4 79 ± 22 -2.3
2.4.16.11. Tertiapin 1ter Apis mellifera Secreted 1 0 5.1 ± 0.3 80 ± 5 -4.6
2.4.36.01. Transforming growth factor beta-1 3rjr Sus scrofa Secreted 2 0 5.8 ± 2.0 82 ± 16 -9.5
2.4.34.01. Type-3 ice-structuring protein HPLC 12 4ny6 Zoarces americanus Secreted 1 0 3.3 ± 0.8 58 ± 9 -5.8
2.4.05.01. Sterol carrier protein 2-like 2 2qzt Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 1.0 ± 2.0 45 ± 12 -3.0
2.4.04.01. Type II inositol 1,4,5-trisphosphate 5-phosphatase 4cml Homo sapiens Endoplasm. reticulum 1 0 4.6 ± 1.1 48 ± 9 -5.1
2.4.07.01. PX domain of serine/threonine-protein kinase Sgk3 1xte Homo sapiens Endosome 1 0 1.2 ± 1.4 77 ± 11 -2.9
2.4.11.01. beta-Purothionin 1bhp Triticum aestivum Secreted 1 0 2.9 ± 2.0 56 ± 19 -4.8
2.4.16.05. Plectasin 3e7r Pseudoplectania nigrella (Ebony cup) Secreted 1 0 2.7 ± 2.3 53 ± 17 -4.0
2.4.51.01. Heme acquisition protein HasA 1b2v Serratia marcescens Secreted 1 0 1.9 ± 1.6 18 ± 18 -3.3
2.4.16.02. Navitoxin 2rty Nasonia vitripennis (Parasitic wasp) Secreted 1 0 1.2 ± 3.4 90 ± 17 -3.9
2.4.06.01. STAR-related lipid transfer protein from bacteria 3qsz Xanthomonas axonopodis Bact. Gram-neg inner 1 0 3.7 ± 1.4 58 ± 15 -3.0
2.4.33.01. 72 kDa type IV collagenase, 32-452 1eak Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.6 37 ± 6 -6.6
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase 4fdo Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 4.3 ± 1.1 67 ± 4 -5.3
2.4.50.01. Matrix protein, Indiana virus, complex with mRNA export factor 4owr Vesicular stomatitis virus Viral 1 0 2.1 ± 0.8 65 ± 2 -7.6
2.4.11.01. Viscotoxin A1 3c8p Viscum album Secreted 1 0 2.3 ± 0.9 45 ± 7 -4.9
2.4.16.07. Diapause-specific peptide 2e2f Gastrophysa atrocyanea (Leaf beetle) Secreted 1 0 1.3 ± 1.0 30 ± 10 -4.2
2.4.17.01. Vitellogenin 1lsh Ichthyomyzon unicuspus (Silver lamprey) Secreted 1 0 3.4 ± 1.3 81 ± 0 -4.6
2.4.16.13 Copsin 2mn5 Coprinopsis cinerea Secreted 1 0 3.0 ± 1.5 59 ± 9 -5.9
2.4.24.01. Mandelate racemase/muconate lactonizing enzyme 1wue Enterococcus faecalis Undefined 2 0 4.0 ± 0.3 86 ± 10 -5.5
2.4.06.01. StAR-related lipid transfer protein 13 2pso Homo sapiens Eukaryo. plasma 1 0 3.1 ± 4.0 77 ± 27 -4.6
2.4.03.01. Tubby protein 3c5n Homo sapiens Eukaryo. plasma 1 0 3.4 ± 0.4 75 ± 5 -7.6
2.4.25.01. N-alpha-acetyltransferase 60, structure 2 5hh0 Homo sapiens Golgi 1 0 5.2 ± 0.0 46 ± 1 -10.7
2.4.16.01. Tx10 alpha-like toxin 1kv0 Buthus martensii Secreted 1 0 1.9 ± 1.1 83 ± 11 -4.6
2.4.16.01. Alpha-like toxin CsEv5 1i6f Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.4 ± 1.3 59 ± 4 -5.8
2.4.04.01. Beta-hemolysin 3i48 Staphylococcus aureus Secreted 1 0 2.8 ± 0.8 57 ± 5 -5.1
2.4.34.01. Ice-structuring protein RD3 1c89 Lycodichthys dearborni Secreted 1 0 3.0 ± 1.0 85 ± 9 -8.7
2.4.05.01. Sterol carrier protein 2 1pz4 Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.8 ± 5.0 37 ± 49 -1.3
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 2 4ph7 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.5 ± 0.9 75 ± 2 -6.4
2.4.07.01. PX domain of sorting nexin-17 (SNX17) 3fog Homo sapiens Endosome 1 0 3.4 ± 1.0 69 ± 12 -4.9
2.4.11.01. Hellethionin D 1nbl Helleborus purpurascens Secreted 1 0 2.2 ± 0.9 45 ± 9 -7.4
2.4.16.02. Defensin heliomicin 1i2u Heliothis virescens (Tobacco budworm moth) Secreted 1 0 3.4 ± 0.4 59 ± 1 -7.6
2.4.51.01. Heme acquisition protein HasA, different strain 3wah Pseudomonas aeruginosa Secreted 1 0 3.4 ± 0.6 14 ± 3 -5.1
2.4.16.14. U3-scytotoxin-Sth1a 5fzv Scytodes thoracica Secreted 1 0 4.3 ± 3.2 76 ± 4 -7.2
2.4.06.04. STAR-related bacterial protein 2d4r Thermus thermophilus Bact. Gram-neg inner 1 0 6.9 ± 2.2 28 ± 6 -7.1
2.4.33.01. 72 kDa type IV collagenase, complex with inhibitor-2 1gxd Homo sapiens Eukaryo. plasma 2 0 2.5 ± 1.1 77 ± 4 -5.4
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase, another loop disordered 4ff6 Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 3.4 ± 1.5 19 ± 6 -6.4
2.4.44.01. Membrane-associated protein VP24, with karyopherin 4u2x Zaire ebolavirus Viral 2 0 4.5 ± 2.1 33 ± 15 -4.3
2.4.16.01. Neurotoxin BmK-M10 2kbk Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 1.7 ± 1.0 73 ± 14 -2.4
2.4.16.02. Termicin 1mm0 Pseudacanthotermes spiniger Secreted 1 0 4.2 ± 0.5 81 ± 3 -3.3
2.4.33.02. Collagenase 2y3u Clostridium histolyticum Secreted 1 0 3.0 ± 1.0 89 ± 4 -5.4
2.4.37.01. Monalysin 4mjt Pseudomonas entomophila Secreted 9 0 1.6 ± 0.0 90 ± 0 -13.5
2.4.06.03. S-norcoclaurine synthase 2vq5 Thalictrum flavum (Yellow meadow rue) Undefined 4 0 2.6 ± 0.3 90 ± 0 -7.0
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1t27 Rattus norvegicus Eukaryo. plasma 1 0 2.3 ± 1.9 12 ± 12 -4.1
2.4.07.01. PX domain of sorting nexin-14 4bgj Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 72 ± 22 -4.3
2.4.06.01. START and PH domains of collagen type IV alpha-3-binding protein 5jjd Homo sapiens Golgi 1 0 1.4 ± 2.6 48 ± 16 -4.4
2.4.16.01. LQH III alpha-like toxin 1fh3 Leiurus quinquestriatus hebraeus Secreted 1 0 3.6 ± 1.5 83 ± 16 -5.2
2.4.16.01. Kurtoxin 1t1t Parabuthus transvaalicus Secreted 1 0 3.8 ± 0.8 88 ± 11 -5.9
2.4.06.03. Class 10 plant pathogenesis-related protein 2qim Lupinus luteus Secreted 1 0 3.3 ± 1.4 41 ± 3 -3.1
2.4.34.01. Ice-structuring protein SP2(HPLC 1) 1ops Zoarces americanus Secreted 1 0 2.4 ± 1.4 60 ± 12 -4.8
2.4.07.01. Bud emergence protein 1 2v6v Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.1 ± 1.2 75 ± 6 -5.1
2.4.06.01. Second StART domain of Lam4 6bym Saccharomyces cerevisiae Endoplasm. reticulum 2 0 3.0 ± 0.8 85 ± 23 -5.2
2.4.07.01. Sorting nexin-5 3hpc Rattus norvegicus Endosome 1 0 0.0 ± 2.1 90 ± 8 -2.4
2.4.11.01. Alpha-1-purothionin 2plh Triticum aestivum Secreted 1 0 2.4 ± 2.0 53 ± 17 -4.6
2.4.16.04. Defensin-like protein 1 1gps Triticum aestivum Secreted 1 0 3.4 ± 1.3 22 ± 9 -3.9
2.4.51.01. Heme acquisition protein HasA 4jet Yersinia pestis Secreted 1 0 4.8 ± 0.9 29 ± 2 -7.0
2.4.16.14. U3-scytotoxin-Sth1h 5fzw Scytodes thoracica Secreted 1 0 3.6 ± 3.4 83 ± 9 -5.1
2.4.20.02. Arylamine N-acetyltransferase 1w4t Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 2.8 ± 0.4 82 ± 1 -5.8
2.4.33.01. 72 kDa type IV collagenase, full-length 1ck7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 73 ± 9 -4.0
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 1 1zhx Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.9 90 ± 7 -5.0
2.4.09.01. T4 capsid assembly protease, gp21 5jbl Enterobacteria phage T4 Viral 5 0 3.6 ± 0.2 89 ± 0 -12.0
2.4.16.01. Beta-insect excitatory toxin BmK IT-AP 1t0z Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 3.9 ± 1.2 79 ± 10 -7.2
2.4.16.02. Phormicin 1ica Protophormia terraenovae (Northern blowfly) Secreted 1 0 3.7 ± 2.3 90 ± 23 -5.0