PDB ID or protein name

Alpha + Beta monotopic/peripheral superfamilies

2.4.001. FAD-linked reductases (1 family)
2.4.002. NTF2-like (1 family) CL0051 (Pfam)
2.4.003. Transcriptional factor tubby (1 family) PF01167 (Pfam)
2.4.004. DNase I-like (1 family)
2.4.005. Sterol carrier protein (2 families) CL0311 (Pfam)
2.4.006. Bet v1-like (5 families) CL0209 (Pfam)
2.4.007. PX domain (1 family) PF00787 (Pfam)
2.4.008. Ribonuclease-like (1 family)
2.4.009. Cytomegalovirus assemblin (1 family)
2.4.010. PreATP-grasp domain (1 family)
2.4.011. Plant thionin (1 family) 1.C.44 (TCDB) PF00321 (Pfam)
2.4.012. Liver-expressed antimicrobial peptide (1 family) PF07359 (Pfam)
2.4.013. OSBP-related proteins (1 family) PF01237 (Pfam)
2.4.014. Phospholipid acyltransferase (1 family) PF01553 (Pfam)
2.4.015. Negative factor (Nef) protein (1 family) PF00469 (Pfam)
2.4.016. Scorpion toxin-like knottin (13 families) CL0054 (Pfam)
2.4.017. Apolipoprotein of LDL particles (1 family) PF01347 (Pfam)
2.4.018. NTN hydrolase superfamily (1 family) CL0052 (Pfam)
2.4.019. GlnB-like superfamily (1 family) CL0089 (Pfam)
2.4.020. Peptidase clan CA (4 families) CL0125 (Pfam)
2.4.021. Peptidase MD (2 families) CL0170 (Pfam)
2.4.022. FAD binding domain (1 family) PF01565 (Pfam)
2.4.023. Heme NO and oxygen binding like (1 family) CL0210 (Pfam)
2.4.024. Enolase like TIM barrel (1 family) CL0256 (Pfam)
2.4.025. N-acetyltransferase like (1 family) CL0257 (Pfam)
2.4.026. HIT superfamily (1 family) CL0265 (Pfam)
2.4.027. AIG2/ChaC-like superfamily (1 family) CL0278 (Pfam)
2.4.028. DAP epimerase superfamily (1 family) CL0288 (Pfam)
2.4.029. Superantigen toxins (1 family) CL0386 (Pfam)
2.4.030. TRAF domain-like superfamily (1 family) CL0389 (Pfam)
2.4.031. Fibrinogen (1 family) CL0422 (Pfam)
2.4.032. Acid phosphatase/Vanadium-dependent haloperoxidase (1 family) CL0525 (Pfam)
2.4.033. PGBD superfamily (2 families) CL0244 (Pfam)
2.4.034. Type III antifreeze protein (1 family) PF08666 (Pfam)
2.4.035. Catalase (1 family) PF00199 (Pfam)
2.4.036. Transforming growth factor (TGF)-beta (1 family) PF00688 (Pfam)
2.4.037. Monalysin (1 family)
2.4.038. PRELI/MSF1 (1 family) PF04707 (Pfam)
2.4.040. IpaB/EvcA family (1 family) PF03278 (Pfam)
2.4.041. Hepatitis C virus non-structural protein NS2 (1 family) PF01538 (Pfam)
2.4.042. Bactericidal permeability increasing protein family (1 family) 1.C.40 (TCDB) PF01273 (Pfam)
2.4.043. OmpA (1 family) PF00691 (Pfam)
2.4.044. Filovirus protein VP24 (1 family) PF06389 (Pfam)
2.4.049. Inositol-pentakisphosphate 2-kinase (1 family) PF06090 (Pfam)
2.4.050. Vesiculovirus matrix protein (1 family) PF06326 (Pfam)
2.4.051. Heme-binding protein A (1 family) PF06438 (Pfam)
2.4.052. Spondin (1 family) PF06468 (Pfam)
2.4.053. Resistin (1 family) PF06954 (Pfam)
See list of these PDB codes

Alpha + Beta monotopic/peripheral (233 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.4.16.12. Actinomycesin 2ru0 Actinomyces sp. Secreted 1 0 3.5 ± 0.7 83 ± 7 -4.1
2.4.05.01. Uncharacterized protein 3bkr Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.4 ± 6.2 50 ± 73 -1.2
2.4.05.01. Sterol carrier protein 2-like 2 2qzt Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 1.0 ± 2.0 45 ± 12 -3.0
2.4.05.01. Sterol carrier protein 2 1pz4 Aedes aegypti (Yellowfever mosquito) Eukaryo. plasma 1 0 0.8 ± 5.0 37 ± 49 -1.3
2.4.16.01. Alpha-mammal toxin AaH2 1aho Androctonus australis (Sahara scorpion) Secreted 1 0 1.7 ± 1.0 64 ± 17 -3.4
2.4.16.03. Potassium channel toxin alpha-KTx 3.1 3odv Androctonus mauretanicus mauretanicus (Scorpion) Secreted 1 0 2.6 ± 0.9 84 ± 5 -5.1
2.4.16.02. Defensin 2nz3 Anopheles gambiae (African malaria mosquito) Secreted 1 0 6.7 ± 1.3 84 ± 10 -7.4
2.4.16.11. Tertiapin 1ter Apis mellifera Secreted 1 0 5.1 ± 0.3 80 ± 5 -4.6
2.4.16.04. Defensin-like protein 32 2mz0 Arabidopsis thaliana Secreted 1 0 2.6 ± 1.4 19 ± 8 -3.4
2.4.16.04. Defensin-like protein 195 1jxc Arabidopsis thaliana Secreted 1 0 4.0 ± 1.5 21 ± 20 -3.9
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 2 4axd Arabidopsis thaliana Eukaryo. plasma 1 0 1.5 ± 0.1 88 ± 4 -4.0
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 3 4axc Arabidopsis thaliana Eukaryo. plasma 1 0 3.2 ± 2.3 68 ± 15 -4.5
2.4.49.01. Inositol-pentakisphosphate 2-kinase, structure 1 2xar Arabidopsis thaliana Eukaryo. plasma 1 0 2.6 ± 1.6 69 ± 7 -6.1
2.4.05.01. Uncharacterized protein 3cnu Archaeoglobus fulgidus Archaebac. 1 0 7.6 ± 1.7 69 ± 20 -7.0
2.4.16.02. Defensin ARD1 1ozz Archaeoprepona demophon Secreted 1 0 4.9 ± 1.7 31 ± 17 -7.1
2.4.16.05. Micasin 2lr5 Arthroderma otae Secreted 1 0 8.3 ± 0.6 58 ± 6 -7.8
2.4.04.01. Sphingomyelinase C 2ddt Bacillus cereus Secreted 1 0 4.1 ± 1.1 59 ± 8 -7.6
2.4.16.09. S-locus pollen protein 1ugl Brassica campestris (Field mustard) Secreted 1 0 1.3 ± 0.6 51 ± 5 -3.4
2.4.01.01. Cholesterol oxidase 1coy Brevibacterium sterolicum Bact. Gram-pos plas. 1 0 4.4 ± 1.1 43 ± 10 -6.8
2.4.16.03. Toxin I5a 1sis Buthus eupeus Secreted 1 0 3.1 ± 1.4 74 ± 16 -4.4
2.4.16.01. Alpha-like neurotoxin BmK-I 1djt Buthus martensii Secreted 2 0 3.8 ± 0.9 90 ± 15 -6.9
2.4.16.01. Tx10 alpha-like toxin 1kv0 Buthus martensii Secreted 1 0 1.9 ± 1.1 83 ± 11 -4.6
2.4.16.01. Neurotoxin 1dq7 Buthus tamulus Secreted 1 0 5.9 ± 1.8 88 ± 18 -8.1
2.4.06.04. STAR-related bacterial protein 1t17 Caulobacter crescentus Undefined 1 0 3.4 ± 0.7 63 ± 2 -8.1
2.4.16.01. Alpha-toxin Cn12 1pe4 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.1 ± 2.3 17 ± 13 -3.1
2.4.16.03. Potassium channel toxin gamma-KTx 1.1 1ne5 Centruroides noxius (Mexican scorpion) Secreted 1 0 3.9 ± 1.0 62 ± 2 -5.2
2.4.16.01. Beta-mammal toxin Cn2 2yc1 Centruroides noxius (Mexican scorpion) Secreted 1 0 2.8 ± 1.1 68 ± 9 -3.8
2.4.16.01. Beta-toxin Cn5 2kja Centruroides noxius (Mexican scorpion) Secreted 1 0 4.1 ± 1.1 73 ± 6 -7.0
2.4.16.01. Toxin CsEv3 2sn3 Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.3 74 ± 17 -5.5
2.4.16.01. Beta-toxin CsEI 1b3c Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.9 ± 1.2 70 ± 7 -3.9
2.4.16.01. Neurotoxin 2 1jza Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.0 ± 1.7 68 ± 15 -5.6
2.4.16.01. Toxin CsEv1 1vna Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.9 ± 1.0 65 ± 10 -7.8
2.4.16.01. Alpha-toxin CsE5 1nra Centruroides sculpturatus (Bark scorpion) Secreted 1 0 2.3 ± 1.2 89 ± 22 -4.3
2.4.16.01. Alpha-like toxin CsEv5 1i6f Centruroides sculpturatus (Bark scorpion) Secreted 1 0 4.4 ± 1.3 59 ± 4 -5.8
2.4.33.02. Collagenase 2y3u Clostridium histolyticum Secreted 1 0 3.0 ± 1.0 89 ± 4 -5.4
2.4.16.13 Copsin 2mn5 Coprinopsis cinerea Secreted 1 0 3.0 ± 1.5 59 ± 9 -5.9
2.4.16.02. Coprisin 2ln4 Copris tripartitus Secreted 1 0 4.5 ± 0.6 42 ± 4 -5.3
2.4.11.01. Crambin 1ejg Crambe abyssinica Secreted 1 0 4.0 ± 1.7 79 ± 15 -7.0
2.4.16.02. Defensin 2b68 Crassostrea gigas (Pacific oyster) Secreted 1 0 5.8 ± 1.7 28 ± 20 -4.0
2.4.32.01. Vanadium chloroperoxidase 3bb0 Curvularia inaequalis Secreted 1 0 3.8 ± 0.8 52 ± 6 -5.3
2.4.06.04. STAR-related bacterial protein 3ggn Deinococcus radiodurans Undefined 1 0 5.2 ± 1.6 53 ± 8 -4.1
2.4.16.10. Toxin MIT1 (Black mamba intestinal toxin 1) 1imt Dendroaspis polylepis polylepis (Black mamba) Secreted 1 0 4.8 ± 0.7 70 ± 3 -9.1
2.4.11.01. Crambin, enantiomer 3ue7 Designed proteins Undefined 1 0 3.4 ± 1.7 89 ± 13 -4.6
2.4.16.02. Drosomycin 1myn Drosophila melanogaster Secreted 1 0 4.6 ± 1.2 10 ± 17 -6.0
2.4.09.01. T4 capsid assembly protease, gp21 5jbl Enterobacteria phage T4 Viral 5 0 3.6 ± 0.2 89 ± 0 -12.0
2.4.28.01. Phenazine biosynthesis protein PhzF 1s7j Enterococcus faecalis Undefined 1 0 1.8 ± 0.7 77 ± 2 -4.3
2.4.24.01. Mandelate racemase/muconate lactonizing enzyme 1wue Enterococcus faecalis Undefined 2 0 4.0 ± 0.3 86 ± 10 -5.5
2.4.42.01. Latherin 3zpm Equus caballus Secreted 1 0 6.0 ± 0.4 75 ± 1 -8.0
2.4.16.05. Eurocin 2lt8 Eurotium amstelodami Secreted 1 0 5.3 ± 1.3 84 ± 12 -5.5
2.4.16.07. Diapause-specific peptide 2e2f Gastrophysa atrocyanea (Leaf beetle) Secreted 1 0 1.3 ± 1.0 30 ± 10 -4.2
2.4.16.01. Tau-theraphotoxin-Hs1a 2n9z Haplopelma schmidti Secreted 1 0 6.1 ± 1.3 68 ± 10 -5.6
2.4.16.02. Defensin heliomicin 1i2u Heliothis virescens (Tobacco budworm moth) Secreted 1 0 3.4 ± 0.4 59 ± 1 -7.6
2.4.11.01. Hellethionin D 1nbl Helleborus purpurascens Secreted 1 0 2.2 ± 0.9 45 ± 9 -7.4
2.4.41.01. Hepatitis C virus non-structural protein NS2 (955-1026) 2hd0 Hepatitis C virus Endoplasm. reticulum 2 0 6.7 ± 0.6 85 ± 0 -11.8
2.4.16.08. Theromacin 2ln8 Hirudo medicinalis Secreted 1 0 3.7 ± 0.2 72 ± 3 -6.4
2.4.20.04. Group XVI phospholipase A1/A2 2kyt Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.5 62 ± 18 -4.9
2.4.04.01. Sphingomyelin phosphodiesterase 3 5uvg Homo sapiens Golgi 1 0 2.9 ± 1.6 59 ± 13 -5.1
2.4.42.01. Cholesteryl ester transfer protein 2obd Homo sapiens Secreted 1 0 7.4 ± 2.9 26 ± 6 -7.0
2.4.06.01. StAR-related lipid transfer protein 5 2r55 Homo sapiens Eukaryo. plasma 1 0 1.7 ± 1.2 47 ± 19 -4.8
2.4.07.01. Sorting nexin-23 (Kinesin-like protein KIF16B) 2v14 Homo sapiens Endosome 1 0 3.3 ± 3.0 72 ± 14 -5.4
2.4.07.01. NADPH oxidase organizer 1, PX domain 2l73 Homo sapiens Eukaryo. plasma 1 0 2.8 ± 1.9 72 ± 13 -5.1
2.4.06.01. Steroidogenic acute regulatory protein, mitochondrial 3p0l Homo sapiens Mitochon. outer 1 0 3.0 ± 1.3 76 ± 10 -4.7
2.4.07.01. Sorting nexin-11, conformation 1 4ikb Homo sapiens Eukaryo. plasma 1 0 5.2 ± 2.7 61 ± 8 -6.1
2.4.05.01. Sterol carrier protein 2 like domain of multifunctional enzyme type 2 1ikt Homo sapiens Peroxisome 1 0 3.5 ± 1.2 75 ± 17 -4.0
2.4.07.01. Nischarin 3p0c Homo sapiens Endosome 1 0 4.1 ± 0.5 82 ± 13 -7.0
2.4.42.01. Bactericidal permeability-increasing protein 1bp1 Homo sapiens Secreted 1 0 1.5 ± 2.4 51 ± 17 -4.3
2.4.03.01. Tubby protein homolog 1s31 Homo sapiens Eukaryo. plasma 1 0 6.8 ± 1.0 71 ± 2 -7.6
2.4.06.01. START domain of collagen type IV alpha-3-binding protein 2e3q Homo sapiens Golgi 1 0 4.3 ± 2.0 41 ± 17 -3.7
2.4.06.01. Phosphatidylcholine transfer protein 1ln1 Homo sapiens Eukaryo. plasma 1 0 3.8 ± 1.8 53 ± 16 -4.8
2.4.07.01. Sorting nexin-11, conformation 2 4ikd Homo sapiens Eukaryo. plasma 1 0 3.0 ± 1.2 58 ± 4 -5.3
2.4.07.01. PX domain of NADH oxidase (p40phox), ligand-bound 1h6h Homo sapiens Endosome 1 0 3.9 ± 2.0 55 ± 14 -6.0
2.4.04.01. Type II inositol 1,4,5-trisphosphate 5-phosphatase 4cml Homo sapiens Endoplasm. reticulum 1 0 4.6 ± 1.1 48 ± 9 -5.1
2.4.04.01. Inositol polyphosphate 5-phosphatase OCRL-1 4cmn Homo sapiens Endosome 1 0 6.7 ± 1.6 83 ± 2 -9.2
2.4.33.01. 72 kDa type IV collagenase, 32-452 1eak Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.6 37 ± 6 -6.6
2.4.06.01. STAR-related lipid transfer protein 11, apoprotein (open state) 2e3m Homo sapiens Golgi 1 0 3.4 ± 1.1 44 ± 12 -6.1
2.4.06.01. StAR-related lipid transfer protein 13 2pso Homo sapiens Eukaryo. plasma 1 0 3.1 ± 4.0 77 ± 27 -4.6
2.4.03.01. Tubby protein 3c5n Homo sapiens Eukaryo. plasma 1 0 3.4 ± 0.4 75 ± 5 -7.6
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-bound 1o7k Homo sapiens Endosome 1 0 15.2 ± 1.7 60 ± 15 -18.4
2.4.20.01. Cathepsin F 1m6d Homo sapiens Lysosome 1 0 4.3 ± 0.8 80 ± 3 -11.7
2.4.07.01. PX domain of sorting nexin-10 4on3 Homo sapiens Endosome 1 0 5.2 ± 1.6 69 ± 5 -7.7
2.4.33.01. 72 kDa type IV collagenase, complex with inhibitor-2 1gxd Homo sapiens Eukaryo. plasma 2 0 2.5 ± 1.1 77 ± 4 -5.4
2.4.07.01. PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide 2wwe Homo sapiens Golgi 1 0 2.5 ± 1.3 56 ± 16 -4.8
2.4.07.01. PX domain of sorting nexin-14 4bgj Homo sapiens Eukaryo. plasma 1 0 2.7 ± 2.2 72 ± 22 -4.3
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens Endosome 1 0 2.4 ± 1.6 88 ± 12 -4.6
2.4.33.01. 72 kDa type IV collagenase, full-length 1ck7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.7 73 ± 9 -4.0
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1uw5 Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.5 18 ± 16 -5.4
2.4.30.01. TNF receptor-associated factor 2 1d01 Homo sapiens Eukaryo. plasma 3 0 3.5 ± 0.0 90 ± 0 -5.7
2.4.52.01. Spondin-2 3d34 Homo sapiens Secreted 1 0 6.3 ± 0.7 35 ± 5 -10.4
2.4.06.01. Lipid transport protein Mln64 (StARD3) 1em2 Homo sapiens Endosome 1 0 2.0 ± 1.1 82 ± 12 -5.0
2.4.12.01. Liver-expressed antimicrobial peptide 2 2l1q Homo sapiens Secreted 1 0 5.3 ± 1.4 56 ± 11 -2.7
2.4.04.01. Type II inositol-1,4,5-trisphosphate 5-phosphatase 3n9v Homo sapiens Eukaryo. plasma 1 0 4.1 ± 1.4 63 ± 6 -6.0
2.4.25.01. N-alpha-acetyltransferase 60, structure 1 5hgz Homo sapiens Golgi 1 0 5.7 ± 1.1 41 ± 7 -8.5
2.4.07.01. PX domain of serine/threonine-protein kinase Sgk3 1xte Homo sapiens Endosome 1 0 1.2 ± 1.4 77 ± 11 -2.9
2.4.08.01. Eosinophil cationic protein 1h1h Homo sapiens 1 0 3.5 ± 1.0 88 ± 6 -7.3
2.4.31.01. Ficolin-1 2wnp Homo sapiens Eukaryo. plasma 1 0 3.0 ± 0.8 65 ± 2 -5.3
2.4.25.01. N-alpha-acetyltransferase 60, structure 2 5hh0 Homo sapiens Golgi 1 0 5.2 ± 0.0 46 ± 1 -10.7
2.4.06.01. Acyl-coenzyme A thioesterase 11 3fo5 Homo sapiens Endoplasm. reticulum 1 0 2.3 ± 1.4 57 ± 7 -3.9
2.4.07.01. PX domain of sorting nexin-17 (SNX17) 3fog Homo sapiens Endosome 1 0 3.4 ± 1.0 69 ± 12 -4.9
2.4.06.01. START and PH domains of collagen type IV alpha-3-binding protein 5jjd Homo sapiens Golgi 1 0 1.4 ± 2.6 48 ± 16 -4.4
2.4.07.01. PX domain of C2alpha-PI3 kinase 2ar5 Homo sapiens Eukaryo. plasma 1 0 5.6 ± 0.9 83 ± 17 -3.7
2.4.16.04. Defensin-like protein 1 1gpt Hordeum vulgare Secreted 1 0 3.1 ± 1.6 28 ± 18 -2.0
2.4.11.01. Beta-hordothionin 1wuw Hordeum vulgare Secreted 1 0 3.6 ± 1.1 55 ± 15 -5.4
2.4.15.01. Protein Nef (HIV HV1LW) 2nef Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 6.3 ± 1.4 73 ± 3 -7.9
2.4.15.01. Protein Nef, N-terminal helix (HIV HV1B1) 1zec Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.6 ± 4.1 89 ± 2 -6.8
2.4.15.01. Protein Nef 1avv Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.0 ± 1.5 75 ± 13 -3.4
2.4.15.01. Protein Nef (HIV 9HIV1) 2xi1 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 4.3 ± 0.6 57 ± 5 -5.0
2.4.15.01. Protein Nef, complex with tyrosine-protein kinase SH3 domain (HIV HV1A2) 3rbb Human immunodeficiency virus type 1 Eukaryo. plasma 2 0 2.4 ± 1.1 84 ± 6 -4.2
2.4.16.08. Hydramacin-1 2k35 Hydra vulgaris Secreted 1 0 2.0 ± 0.2 87 ± 2 -4.3
2.4.17.01. Vitellogenin 1lsh Ichthyomyzon unicuspus (Silver lamprey) Secreted 1 0 3.4 ± 1.3 81 ± 0 -4.6
2.4.13.01. Protein Osh1 5h2d Kluyveromyces lactis Vacuole 1 0 0.4 ± 2.4 71 ± 26 -2.7
2.4.16.03. Charybdotoxin 2crd Leiurus quinquestriatus hebraeus Secreted 1 0 1.1 ± 1.5 86 ± 15 -3.2
2.4.16.01. Beta-insect depressant toxin LqhIT2 2i61 Leiurus quinquestriatus hebraeus Secreted 1 0 4.3 ± 1.6 80 ± 21 -3.7
2.4.16.01. Alpha-insect toxin LqhaIT 2yeo Leiurus quinquestriatus hebraeus Secreted 1 0 3.5 ± 0.8 43 ± 13 -5.9
2.4.16.01. LQH III alpha-like toxin 1fh3 Leiurus quinquestriatus hebraeus Secreted 1 0 3.6 ± 1.5 83 ± 16 -5.2
2.4.16.01. Alpha-insect toxin Lqq3 1lqq Leiurus quinquestriatus quinquestriatus Secreted 1 0 0.8 ± 1.0 80 ± 6 -3.3
2.4.16.03. Chlorotoxin 1chl Leiurus quinquestriatus quinquestriatus Secreted 1 0 6.5 ± 1.2 87 ± 14 -4.3
2.4.16.04. Defensin Lc-def 2lj7 Lens culinaris Secreted 1 0 2.2 ± 0.9 22 ± 10 -3.9
2.4.04.01. Sphingomyelinase C 1zwx Listeria ivanovii Secreted 1 0 6.2 ± 0.5 55 ± 1 -10.1
2.4.21.02. L-alanyl-D-glutamate peptidase 2vo9 Listeria phage A500 Secreted 1 0 3.1 ± 1.0 48 ± 4 -5.2
2.4.16.02. Lucifensin 2lld Lucilia sericata Secreted 1 0 1.1 ± 1.7 11 ± 12 -3.0
2.4.06.03. Class 10 plant pathogenesis-related protein 2qim Lupinus luteus Secreted 1 0 3.3 ± 1.4 41 ± 3 -3.1
2.4.34.01. Ice-structuring protein RD1 1ucs Lycodichthys dearborni Secreted 1 0 2.2 ± 1.0 67 ± 9 -5.5
2.4.34.01. Ice-structuring protein RD3 1c89 Lycodichthys dearborni Secreted 1 0 3.0 ± 1.0 85 ± 9 -8.7
2.4.16.01. Toxin BmKaIT1 1omy Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.0 ± 1.3 83 ± 10 -3.8
2.4.16.01. Toxin Bmka2 2kbj Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.1 ± 1.5 64 ± 15 -3.6
2.4.16.01. Beta-insect excitatory toxin BmKIT1 1wwn Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.2 ± 1.1 72 ± 6 -4.4
2.4.16.01. Alpha-mammal toxin BmK-M8 1snb Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 4.4 ± 2.4 79 ± 22 -2.3
2.4.16.01. Neurotoxin BmK-M10 2kbk Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 1.7 ± 1.0 73 ± 14 -2.4
2.4.16.01. Beta-insect excitatory toxin BmK IT-AP 1t0z Mesobuthus martensii (Manchurian scorpion) Secreted 1 0 3.9 ± 1.2 79 ± 10 -7.2
2.4.06.01. Cholesterol-regulated Start protein 4 (StarD4) 5brl Mus musculus Eukaryo. plasma 1 0 3.7 ± 1.1 67 ± 13 -3.7
2.4.53.01. Resistin 1rfx Mus musculus Secreted 3 0 3.4 ± 1.2 10 ± 6 -8.7
2.4.53.01. Resistin, different conformation 1rgx Mus musculus Secreted 3 0 8.2 ± 1.2 12 ± 6 -12.1
2.4.18.01. Phospholipase B-like protein 3fgr Mus musculus Lysosome 2 0 6.5 ± 2.4 79 ± 8 -5.3
2.4.03.01. Tubby protein, ligand-bound 1i7e Mus musculus Eukaryo. plasma 1 0 3.8 ± 1.9 75 ± 13 -4.7
2.4.03.01. Tubby protein, ligand-free 1c8z Mus musculus Eukaryo. plasma 1 0 2.8 ± 0.9 89 ± 13 -5.8
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1kcm Mus musculus Eukaryo. plasma 1 0 5.3 ± 1.4 59 ± 5 -11.0
2.4.27.01. Gamma-glutamylaminecyclotransferase 1vkb Mus musculus Undefined 1 0 2.3 ± 0.7 72 ± 4 -4.8
2.4.35.01. Catalase-related protein 3e4w Mycobacterium paratuberculosis Undefined 2 0 9.6 ± 1.3 49 ± 6 -13.4
2.4.20.02. Arylamine N-acetyltransferase 1w5r Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 2.6 ± 0.5 82 ± 6 -6.2
2.4.02.01. Epoxide Hydrolase 2bng Mycobacterium tuberculosis Bact. Gram-pos plas. 2 0 8.2 ± 0.6 88 ± 4 -24.0
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase 4fdo Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 4.3 ± 1.1 67 ± 4 -5.3
2.4.22.01. Decaprenylphosphoryl-beta-D-ribose oxidase, another loop disordered 4ff6 Mycobacterium tuberculosis Bact. Gram-pos plas. 1 0 3.4 ± 1.5 19 ± 6 -6.4
2.4.16.06. Mytilin-B 2eem Mytilus edulis (Blue mussel) Secreted 1 0 3.6 ± 1.4 76 ± 8 -3.2
2.4.16.02. Defensin MGD-1 1fjn Mytilus galloprovincialis (Mediterranean mussel) Secreted 1 0 1.5 ± 1.4 43 ± 12 -3.0
2.4.16.02. Nasonin 2koz Nasonia vitripennis (Parasitic wasp) Secreted 1 0 2.9 ± 0.9 68 ± 7 -4.6
2.4.16.04. Flower-specific defensin D1, dimer 4cqk Nicotiana alata (Winged tobacco) Secreted 2 0 4.8 ± 2.4 88 ± 6 -7.1
2.4.16.04. Flower-specific defensin D1, monomer 4ab0 Nicotiana alata (Winged tobacco) Secreted 1 0 3.5 ± 1.2 55 ± 13 -4.3
2.4.16.04. Defensin NsD7, dimer 5vyp Nicotiana suaveolens Secreted 2 0 5.4 ± 0.8 87 ± 7 -7.1
2.4.16.04. Defensin NaD1 1mr4 Nicotiana tabacum Secreted 1 0 4.2 ± 1.8 59 ± 11 -3.0
2.4.16.04. Defensin NsD7 5kk4 Nicotiana tabacum Secreted 2 0 3.5 ± 0.7 80 ± 4 -5.6
2.4.05.01. Sterol carrier protein 2 1c44 Oryctolagus cuniculus Eukaryo. plasma 1 0 3.7 ± 1.2 74 ± 17 -4.8
2.4.16.04. Defensin 3psm Pachyrhizus erosus Secreted 1 0 4.1 ± 1.8 32 ± 8 -5.4
2.4.16.01. Kurtoxin 1t1t Parabuthus transvaalicus Secreted 1 0 3.8 ± 0.8 88 ± 11 -5.9
2.4.16.04. Defensin-like protein 1brz Pentadiplandra brazzeana Secreted 1 0 1.2 ± 1.2 83 ± 10 -3.6
2.4.16.04. Floral defensin-like protein 1 1n4n Petunia hybrida Secreted 1 0 1.8 ± 0.8 6 ± 9 -3.8
2.4.16.04. Defensin 1 1jkz Pisum sativum Secreted 1 0 3.5 ± 1.6 8 ± 19 -5.4
2.4.35.01. 8R-Lipoxygenase, N-terminal domain 1u5u Plexaura homomalla Eukaryo. plasma 1 0 3.1 ± 0.3 72 ± 3 -10.4
2.4.20.03. Protease NSP1 3ifu Porcine reproductive and respiratory syndrome virus Undefined 2 0 5.4 ± 1.2 89 ± 15 -9.8
2.4.16.02. Phormicin 1ica Protophormia terraenovae (Northern blowfly) Secreted 1 0 3.7 ± 2.3 90 ± 23 -5.0
2.4.16.02. Termicin 1mm0 Pseudacanthotermes spiniger Secreted 1 0 4.2 ± 0.5 81 ± 3 -3.3
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 2 5iqw Pseudomonas aeruginosa Secreted 1 0 1.5 ± 0.2 24 ± 5 -4.8
2.4.51.01. Heme acquisition protein HasA, alternative position of heme 3mol Pseudomonas aeruginosa Secreted 1 0 2.9 ± 0.6 40 ± 5 -5.8
2.4.20.02. Arylamine N-acetyltransferase 1w4t Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 2.8 ± 0.4 82 ± 1 -5.8
2.4.51.01. Heme acquisition protein HasA 3ell Pseudomonas aeruginosa Secreted 1 0 3.3 ± 0.4 18 ± 8 -5.5
2.4.05.02. SDS hydrolase SdsA1 2cfu Pseudomonas aeruginosa Secreted 1 0 6.0 ± 2.5 70 ± 4 -7.0
2.4.51.01. Heme acquisition protein HasA, apoprotein, structure 1 3mok Pseudomonas aeruginosa Secreted 1 0 4.5 ± 0.7 37 ± 7 -6.7
2.4.43.01. Cell wall anchor protein of the T6SS system 4b62 Pseudomonas aeruginosa Bact. Gram-neg outer 1 0 2.8 ± 2.5 46 ± 36 -4.6
2.4.51.01. Heme acquisition protein HasA, different strain 3wah Pseudomonas aeruginosa Secreted 1 0 3.4 ± 0.6 14 ± 3 -5.1
2.4.37.01. Monalysin 4mjt Pseudomonas entomophila Secreted 9 0 1.6 ± 0.0 90 ± 0 -13.5
2.4.16.05. Plectasin 3e7r Pseudoplectania nigrella (Ebony cup) Secreted 1 0 2.7 ± 2.3 53 ± 17 -4.0
2.4.16.04. Defensin-like protein 2 2n2r Raphanus sativus Secreted 1 0 2.5 ± 1.7 31 ± 24 -4.2
2.4.16.04. Defensin-like protein 1 1ayj Raphanus sativus Secreted 1 0 11.0 ± 1.9 39 ± 19 -7.4
2.4.06.02. Phosphatidylinositol transfer protein alpha isoform 1t27 Rattus norvegicus Eukaryo. plasma 1 0 2.3 ± 1.9 12 ± 12 -4.1
2.4.19.01. Protein CutA 1osc Rattus norvegicus Eukaryo. plasma 3 0 1.3 ± 0.3 90 ± 1 -5.5
2.4.06.02. Phosphatidylinositol transfer protein beta isoform 2a1l Rattus norvegicus Eukaryo. plasma 1 0 4.7 ± 1.7 36 ± 17 -4.3
2.4.07.01. Sorting nexin-5 3hpc Rattus norvegicus Endosome 1 0 0.0 ± 2.1 90 ± 8 -2.4
2.4.26.01. Putative uncharacterized protein 3nrd Rhizobium meliloti Undefined 2 0 5.8 ± 0.9 86 ± 3 -13.7
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 1 4b2z Saccharomyces cerevisiae Endoplasm. reticulum 1 0 1.3 ± 1.3 86 ± 6 -4.6
2.4.13.01. Oxysterol-binding protein homolog 4 (KES1), N-terminal helix removed 1zi7 Saccharomyces cerevisiae Golgi 1 0 2.5 ± 0.5 75 ± 8 -6.9
2.4.13.01. Oxysterol-binding protein homolog 3 4ic4 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 4.3 ± 0.9 86 ± 29 -5.9
2.4.13.01. Oxysterol-binding protein homolog 6, conformation 2 4ph7 Saccharomyces cerevisiae Endoplasm. reticulum 1 0 2.5 ± 0.9 75 ± 2 -6.4
2.4.07.01. Bud emergence protein 1 2v6v Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.1 ± 1.2 75 ± 6 -5.1
2.4.07.01. PX domain of vacuolar morphogenesis protein VAM7 1kmd Saccharomyces cerevisiae Vacuole 1 0 3.4 ± 1.2 76 ± 8 -7.8
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 2 1zhy Saccharomyces cerevisiae Golgi 1 0 0.9 ± 0.4 87 ± 4 -4.7
2.4.07.01. PX domain of sorting nexin GRD19, ligand-bound 1ocu Saccharomyces cerevisiae Endosome 2 0 15.3 ± 0.8 88 ± 6 -34.9
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 3 4jch Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.2 88 ± 1 -6.0
2.4.07.01. PX domain of sorting nexin GRD19, ligand-free 1ocs Saccharomyces cerevisiae Endosome 1 0 2.5 ± 1.1 88 ± 11 -5.4
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 4 3spw Saccharomyces cerevisiae Golgi 1 0 7.3 ± 1.1 60 ± 9 -4.5
2.4.38.01. Ups1 transporter-Mdm35 complex, structure 1 4xiz Saccharomyces cerevisiae Mitochon. inner 2 0 2.0 ± 1.7 19 ± 13 -4.1
2.4.38.01. Ups1 transporter-Mdm35 complex, structure 2 4ytx Saccharomyces cerevisiae Mitochon. inner 2 0 5.4 ± 1.0 78 ± 0 -6.3
2.4.13.01. Oxysterol-binding protein homolog 4, conformation 1 1zhx Saccharomyces cerevisiae Golgi 1 0 1.2 ± 0.9 90 ± 7 -5.0
2.4.16.02. Sapecin 1l4v Sarcophaga peregrina Secreted 1 0 5.4 ± 1.5 84 ± 18 -5.1
2.4.51.01. Heme acquisition protein HasA, apoprotein 1ybj Serratia marcescens Secreted 1 0 2.8 ± 2.4 33 ± 9 -3.9
2.4.51.01. Heme acquisition protein HasA 1b2v Serratia marcescens Secreted 1 0 1.9 ± 1.6 18 ± 18 -3.3
2.4.40.01. IpgB2 protein 3lxr Shigella flexneri Bact. Gram-neg inner 2 0 2.7 ± 0.4 75 ± 2 -6.7
2.4.15.01. Protein Nef, complex with T-cell surface glycoprotein CD3 zeta chain 3ik5 Simian immunodeficiency virus Eukaryo. plasma 2 0 3.1 ± 0.5 78 ± 7 -4.5
2.4.16.04. Flower-specific gamma-thionin-like protein 4uj0 Solanum lycopersicum Secreted 1 0 2.6 ± 0.9 19 ± 5 -4.8
2.4.29.01. Enterotoxin type A 1dyq Staphylococcus aureus Secreted 1 0 3.9 ± 0.5 82 ± 6 -6.8
2.4.29.01. Superantigen-like protein 3r2t Staphylococcus aureus Undefined 1 0 4.2 ± 0.0 79 ± 1 -6.2
2.4.04.01. Beta-hemolysin 3i48 Staphylococcus aureus Secreted 1 0 2.8 ± 0.8 57 ± 5 -5.1
2.4.01.01. Cholesterol oxidase 1b4v Streptomyces sp. Bact. Gram-pos plas. 1 0 5.4 ± 0.6 39 ± 4 -8.4
2.4.25.01. Uncharacterized N-acetyltransferase SSO0209 2x7b Sulfolobus solfataricus Undefined 1 0 3.9 ± 1.5 49 ± 6 -7.6
2.4.06.05. Thermoacidophile-specific fatty acid carrier 3w9k Sulfolobus tokodaii Archaebac. 1 0 2.7 ± 1.4 47 ± 4 -7.1
2.4.36.01. Transforming growth factor beta-1 3rjr Sus scrofa Secreted 2 0 5.8 ± 2.0 82 ± 16 -9.5
2.4.06.03. S-norcoclaurine synthase 2vq5 Thalictrum flavum (Yellow meadow rue) Undefined 4 0 2.6 ± 0.3 90 ± 0 -7.0
2.4.23.01. Methyl-accepting chemotaxis protein 3eee Thermoanaerobacter tengcongensis Undefined 1 0 3.2 ± 0.9 81 ± 4 -5.9
2.4.14.01. 1-acyl-sn-glycerol-3-phosphate acyltransferase 5kym Thermotoga maritima Bact. Gram-neg inner 1 0 20.2 ± 1.0 28 ± 2 -32.3
2.4.05.01. Sterol carrier protein 2 2cx7 Thermus thermophilus Bact. Gram-neg inner 1 0 4.7 ± 1.3 73 ± 13 -6.9
2.4.06.04. STAR-related bacterial protein 2d4r Thermus thermophilus Bact. Gram-neg inner 1 0 6.9 ± 2.2 28 ± 6 -7.1
2.4.16.01. Toxin VII 1npi Tityus serrulatus Secreted 1 0 4.6 ± 1.5 52 ± 16 -6.7
2.4.11.01. beta-Purothionin 1bhp Triticum aestivum Secreted 1 0 2.9 ± 2.0 56 ± 19 -4.8
2.4.16.04. Defensin-like protein 1 1gps Triticum aestivum Secreted 1 0 3.4 ± 1.3 22 ± 9 -3.9
2.4.11.01. Alpha-1-purothionin 2plh Triticum aestivum Secreted 1 0 2.4 ± 2.0 53 ± 17 -4.6
2.4.50.01. Matrix protein, Indiana virus 1lg7 Vesicular stomatitis virus Viral 1 0 2.7 ± 0.4 82 ± 2 -7.3
2.4.50.01. Matrix protein, New Jersey virus 2w2r Vesicular stomatitis virus Viral 1 0 4.1 ± 0.1 57 ± 1 -10.4
2.4.50.01. Matrix protein, Indiana virus, complex with mRNA export factor 4owr Vesicular stomatitis virus Viral 1 0 2.1 ± 0.8 65 ± 2 -7.6
2.4.16.04. Defensin 1ti5 Vigna radiata (Mung bean) Secreted 1 0 1.9 ± 2.4 62 ± 16 -3.0
2.4.16.04. Defensin 2 (PDF1) 2gl1 Vigna radiata (Mung bean) Secreted 1 0 2.8 ± 0.6 6 ± 4 -5.7
2.4.11.01. Viscotoxin A3 1okh Viscum album Secreted 1 0 4.6 ± 1.3 32 ± 19 -4.9
2.4.11.01. Viscotoxin B 1jmp Viscum album Secreted 1 0 1.2 ± 1.4 52 ± 13 -3.2
2.4.11.01. Viscotoxin A2 1jmn Viscum album Secreted 1 0 2.3 ± 0.3 63 ± 8 -3.3
2.4.11.01. Viscotoxin A1 3c8p Viscum album Secreted 1 0 2.3 ± 0.9 45 ± 7 -4.9
2.4.06.01. STAR-related lipid transfer protein from bacteria 3qsz Xanthomonas axonopodis Bact. Gram-neg inner 1 0 3.7 ± 1.4 58 ± 15 -3.0
2.4.20.01. Cysteine protease 3ois Xylella fastidiosa Undefined 1 0 3.2 ± 0.2 80 ± 4 -6.4
2.4.51.01. Heme acquisition protein HasA, apoprotein 4jes Yersinia pestis Secreted 1 0 5.2 ± 0.3 40 ± 2 -9.6
2.4.51.01. Heme acquisition protein HasA 4jet Yersinia pestis Secreted 1 0 4.8 ± 0.9 29 ± 2 -7.0
2.4.51.01. Heme acquisition protein HasA 4xzd Yersinia pseudotuberculosis Secreted 1 0 3.5 ± 0.4 25 ± 2 -5.9
2.4.51.01. Heme acquisition protein HasA, dimer 4y4s Yersinia pseudotuberculosis Secreted 1 0 1.8 ± 1.1 83 ± 9 -4.2
2.4.44.01. Membrane-associated protein VP24, with karyopherin 4u2x Zaire ebolavirus Viral 2 0 4.5 ± 2.1 33 ± 15 -4.3
2.4.34.01. Type-3 ice-structuring protein HPLC 12 4ny6 Zoarces americanus Secreted 1 0 3.3 ± 0.8 58 ± 9 -5.8
2.4.34.01. Ice-structuring protein SP2(HPLC 1) 1ops Zoarces americanus Secreted 1 0 2.4 ± 1.4 60 ± 12 -4.8
2.4.34.01. Type III antifreeze protein nfeAFP11 2lx2 Zoarces elongatus Secreted 1 0 5.3 ± 1.0 53 ± 5 -7.0
2.4.34.01. Ice-structuring protein 4ur4 Zoarces viviparus Secreted 1 0 3.2 ± 4.1 68 ± 2 -5.8