PDB ID or protein name

Alpha-helical peptides superfamilies

3.1.001. Topogenic peptides (6 families)
3.1.002. Peptide fragments of transmembrane proteins (16 families)
3.1.003. Membrane anchor helices of peripheral proteins (11 families)
3.1.004. Peptide fragments of water-soluble proteins (10 families)
3.1.005. Designed alpha-helical peptides (13 families)
3.1.006. Apolipoprotein peptides (2 families)
3.1.007. Viral fusion and anchor peptides (10 families)
3.1.008. Antifreeze protein, type I (1 family)
3.1.009. Herpesvirus US12 family (1 family) PF05363 (Pfam)
3.1.010. Alpha-helical bacterial pheromones (1 family)
3.1.011. Peptide hormones (6 families)
3.1.012. Endothelin-like peptides (1 family) PF00322 (Pfam)
3.1.013. Calcitonin (1 family) 1.C.49 (TCDB) PF00214 (Pfam)
3.1.014. Tachykinin family (1 family) PF02202 (Pfam)
3.1.015. Bacteriocin, class IIa (5 families) PF01721 (Pfam)
3.1.016. Bacteriocin, class IIb (1 family)
3.1.017. Bacterial antimicrobial peptides (1 family)
3.1.018. Hemolysing bacterial toxins (2 families)
3.1.019. Peptaibol (1 family) 1.D.5 (TCDB)
3.1.020. Alpha-conotoxin-like (1 family)
3.1.021. Insect antimicrobial peptides (11 families)
3.1.022. Mollusc antimicrobial peptides (1 family)
3.1.023. Meucin (1 family)
3.1.024. Penaeidin (1 family) PF05927 (Pfam)
3.1.025. Latarcin (1 family) PF10279 (Pfam)
3.1.026. Pleurocidin (1 family) 1.C.62 (TCDB) PF08107 (Pfam)
3.1.027. Pardaxin (1 family) PF07425 (Pfam)
3.1.028. Amphibian antimicrobial peptides (9 families)
3.1.029. Cathelicidin (3 families) 1.C.33 (TCDB) PF00666 (Pfam)
3.1.030. Lactotransferrin peptides (1 family)
3.1.031. Dermcidin (1 family) PF15291 (Pfam)
3.1.032. Toxin-antitoxin module (1 family) 1.C.103 (TCDB)
3.1.033. Stage V sporulation protein (1 family) PF08183 (Pfam)
3.1.034. Conotoxin B (1 family)
3.1.035. Plant alpha-helical antimicrobial peptides (1 family)
See list of these PDB codes

Alpha-helical peptides (371 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
3.1.20.01. Alpha-conotoxin CnIA 1b45 Conus consors (Singed cone) Secreted 1 0 0.8 ± 0.8 80 ± 20 -2.1
3.1.02.09. Peptide (659-711) of platelet endothelial cell adhesion molecule 2ky5 Homo sapiens Eukaryo. plasma 1 0 1.0 ± 3.8 89 ± 3 -3.7
3.1.29.01. Cathelin-related peptide SC5 (SMAP-29) 1fry Ovis aries Secreted 1 0 1.1 ± 0.8 18 ± 9 -3.5
3.1.22.01. Antifungal peptide 2mp9 Cenchritis muricatus Secreted 1 0 1.2 ± 1.5 90 ± 26 -3.7
3.1.11.01. Pancreatic hormone 1v1d Bos taurus Secreted 1 0 1.2 ± 3.0 79 ± 32 -1.9
3.1.20.01. Alpha-conotoxin GID 1mtq Conus geographus (Geography cone) Secreted 1 0 1.3 ± 2.5 78 ± 28 -2.4
3.1.24.01. Penaeidin-3a 1ueo Litopenaeus vannamei (Whiteleg shrimp) Secreted 1 0 1.3 ± 3.5 89 ± 2 -5.5
3.1.05.03. LAK160-P7 2l96 Designed proteins Undefined 1 0 1.4 ± 0.9 88 ± 5 -2.7
3.1.20.01. O2-contryphan-Vc1 2n24 Conus victoriae (Queen Victoria cone) Secreted 1 0 1.6 ± 1.0 89 ± 22 -3.6
3.1.21.01. Cecropin-P1 2n92 Ascaris suum Secreted 1 0 1.6 ± 3.4 90 ± 0 -4.1
3.1.20.01. Alpha-conotoxin GIA 1not Conus geographus (Geography cone) Secreted 1 0 1.6 ± 1.5 89 ± 20 -2.3
3.1.11.02. Extendin-4 1jrj Heloderma suspectum Secreted 1 0 1.7 ± 0.8 79 ± 8 -5.0
3.1.30.01. Lactoferrin-based peptide, 21-67 1z6v Homo sapiens Secreted 1 0 1.7 ± 1.4 84 ± 3 -4.9
3.1.04.07. Peptide (119-148) of antifreeze protein Afp1 2lq2 Glaciozyma antarctica Undefined 1 0 1.7 ± 2.4 84 ± 6 -8.6
3.1.15.01. Sakacin P 1ohm Lactobacillus sake Secreted 1 0 1.8 ± 1.1 90 ± 11 -4.4
3.1.20.01. Conotoxin Ar1446 2m61 Conus araneosus Secreted 1 0 1.8 ± 0.8 82 ± 6 -4.0
3.1.02.03. Juxtamembrane helix of ATP synthase subunit b 2khk Escherichia coli Bact. Gram-neg inner 1 0 1.9 ± 0.1 85 ± 3 -3.9
3.1.34.01. Conantokin-R1-B 2mzm Conus rolani Secreted 1 0 1.9 ± 0.7 81 ± 8 -2.9
3.1.11.02. Extendin-4, with extracellular domain of glucagon-like peptide-1 GPCR 3c59 Heloderma suspectum Secreted 2 0 1.9 ± 0.2 64 ± 0 -6.5
3.1.20.01. Alpha-conotoxin ImI 1e75 Conus imperialis (Imperial cone) Secreted 1 0 1.9 ± 0.9 80 ± 15 -3.7
3.1.05.03. Human platelet factor 4 based peptide, 56-70, modified 1djf Designed proteins Undefined 1 0 1.9 ± 1.4 87 ± 8 -4.9
3.1.11.03. Obestatin 2jsi Mus musculus Secreted 1 0 2.0 ± 3.3 85 ± 13 -3.1
3.1.04.08. Truncated superoxide dismutase 1 2mp3 Homo sapiens Eukaryo. plasma 1 0 2.1 ± 2.3 83 ± 0 -6.3
3.1.29.01. Cathelicidin-5 2ndc Bos taurus Secreted 1 0 2.1 ± 2.1 82 ± 17 -3.7
3.1.21.06. Spinigerin 1zrv Pseudacanthotermes spiniger Secreted 1 0 2.1 ± 3.4 77 ± 5 -3.9
3.1.11.05. Parathyroid hormone 1et1 Homo sapiens Secreted 1 0 2.1 ± 0.5 85 ± 3 -5.6
3.1.03.07. N-terminal peptide (24-58) of Disabled homolog 2 2lsw Homo sapiens Vesicle 1 0 2.1 ± 0.6 85 ± 5 -3.8
3.1.11.06. Parathyroid hormone-related peptide, structure 2 3ffd Homo sapiens Secreted 1 0 2.2 ± 1.5 89 ± 3 -5.1
3.1.12.01. Sarafotoxin-M 2ldf Atractaspis microlepidota microlepidota Secreted 1 0 2.3 ± 1.5 30 ± 35 -2.1
3.1.21.01. Cecropin A (1-8) - magainin (1-12) hybrid 1d9j Hyalophora cecropia (Cecropia moth) Secreted 1 0 2.3 ± 0.9 90 ± 10 -6.4
3.1.20.01. O2-contryphan-Vc2 5l34 Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.4 85 ± 8 -4.2
3.1.20.01. Alpha-conotoxin Vc1A 2h8s Conus victoriae (Queen Victoria cone) Secreted 1 0 2.4 ± 0.8 59 ± 6 -2.5
3.1.20.01. Alpha-conotoxin PIVA 1p1p Conus purpurascens (Purple cone) Secreted 1 0 2.4 ± 1.0 30 ± 11 -3.8
3.1.05.03. VG16KRKP peptide, structure 2 2n63 Designed proteins Undefined 1 0 2.5 ± 0.3 57 ± 4 -4.0
3.1.15.01. Curvacin-A 2a2b Lactobacillus curvatus Secreted 1 0 2.5 ± 1.3 34 ± 18 -6.7
3.1.20.01. Alpha-conotoxin EIVA 1pqr Conus ermineus Secreted 1 0 2.5 ± 1.3 14 ± 14 -3.4
3.1.03.06. 12 kDa heat shock protein 4axp Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.5 ± 0.1 74 ± 0 -5.5
3.1.05.03. VG16KRKP peptide, structure 1 2mxh Designed proteins Undefined 1 0 2.5 ± 2.4 82 ± 11 -3.2
3.1.20.01. Alpha-conotoxin PIA 1zlc Conus purpurascens (Purple cone) Secreted 1 0 2.6 ± 1.3 59 ± 16 -4.3
3.1.13.01. Adrenomedullin 2l7s Homo sapiens Secreted 1 0 2.6 ± 0.7 90 ± 5 -6.7
3.1.02.07. Sodium/hydrogen exchanger 1, TM helices 2kbv Homo sapiens Eukaryo. plasma 1 0 2.7 ± 6.9 74 ± 4 -4.9
3.1.20.01. alpha-conotoxin MII 1mii Conus magus Secreted 1 0 2.7 ± 1.8 45 ± 19 -4.2
3.1.04.03. Viral protein R, peptide 13-33, different strain 1fi0 Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 2.7 ± 1.2 88 ± 8 -8.6
3.1.20.01. Alpha-conotoxin S1 1qmw Conus striatus Secreted 1 0 2.8 ± 2.6 43 ± 17 -2.5
3.1.11.02. Glucagon-like peptide 1, with extracellular GPCR domain 3iol Homo sapiens Secreted 2 0 2.8 ± 4.0 70 ± 1 -6.7
3.1.08.01. Antifreeze protein A 1wfb Pseudopleuronectes americanus Secreted 1 0 2.8 ± 1.0 88 ± 1 -10.1
3.1.02.16. Peptide 211-263 of YscU protein 2ml9 Yersinia pseudotuberculosis Bact. Gram-neg inner 1 0 2.9 ± 1.8 82 ± 5 -6.6
3.1.02.02. S4-S5 linker peptide (532-551) of HERG K+ channel 2le7 Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.4 69 ± 9 -5.0
3.1.14.01. Eledoisin 1mxq Eledone cirrhosa (Curled octopus) Secreted 1 0 2.9 ± 1.7 59 ± 19 -5.0
3.1.35.01. Cn-AMP1 peptide 2n0v Cocos nucifera Secreted 1 0 2.9 ± 1.3 73 ± 18 -2.3
3.1.11.01. Neuropeptide F 1k8v Moniezia expansa (Sheep tapeworm) Secreted 1 0 2.9 ± 1.1 68 ± 9 -7.0
3.1.31.01. Dermcidin, structure 2 2ndk Homo sapiens Secreted 1 0 3.0 ± 2.0 86 ± 4 -9.6
3.1.20.01. Alpha-conotoxin OmIA 2gcz Conus omaria (Omaria cone) Secreted 1 0 3.0 ± 1.5 62 ± 11 -3.7
3.1.28.05. Aurein 1.2 analogue 2f3a Designed proteins Undefined 1 0 3.0 ± 1.6 88 ± 24 -11.7
3.1.13.01. Calcitonin 1bku Anguilla japonica (Japanese eel) Secreted 1 0 3.0 ± 0.4 77 ± 3 -8.7
3.1.29.01. Fowlicidin-2 2gdl Gallus gallus Secreted 1 0 3.1 ± 0.5 85 ± 4 -8.9
3.1.29.01. Cathelicidin-3, peptide 121-151 2hfr Gallus gallus Secreted 1 0 3.1 ± 4.2 86 ± 1 -8.0
3.1.07.02. Peptide of envelope glycoprotein H (625-644) 2lqy Human herpesvirus Endosome 1 0 3.2 ± 0.8 88 ± 5 -10.2
3.1.01.02. Leader peptide of bacteriocin microcin B17 2mlp Escherichia coli Secreted 1 0 3.2 ± 3.6 84 ± 4 -6.6
3.1.18.01. Delta-hemolysin 1dtc Staphylococcus aureus Secreted 1 0 3.2 ± 2.2 87 ± 19 -8.5
3.1.28.06. Magainin analogue, MSI-594 2k98 Designed proteins Undefined 1 0 3.2 ± 0.2 86 ± 2 -8.9
3.1.05.07. Penetratin 1omq Designed proteins Undefined 1 0 3.2 ± 1.0 79 ± 7 -7.4
3.1.21.04. Spiderine-1a 2n85 Oxyopes takobius (Lynx spider) Secreted 1 0 3.2 ± 4.2 88 ± 0 -7.8
3.1.07.06. NS2 protease, segment 766-789 of polyprotein 2lzq Hepatitis GB virus Endoplasm. reticulum 1 0 3.2 ± 2.1 88 ± 1 -5.9
3.1.15.04. Bacteriocin plantaricin K (PlnK) 2keg Lactobacillus plantarum Secreted 1 0 3.3 ± 1.1 83 ± 11 -8.4
3.1.06.01. Apolipoprotein A-I, peptide 190-209 1odq Homo sapiens Undefined 1 0 3.3 ± 0.7 87 ± 4 -7.1
3.1.20.01. Alpha-conotoxin-like EpI 1a0m Conus episcopatus (Bishop's cone) Secreted 1 0 3.3 ± 1.2 58 ± 9 -3.2
3.1.03.08. Lipid interacting helix (227-245) of digalactosyldiacylglycerol synthase 2l7c Arabidopsis thaliana Chloroplast outer 1 0 3.3 ± 3.6 88 ± 1 -6.0
3.1.03.03. Membrane-bound helix of phosphotransferase IIA component 1o53 Escherichia coli Bact. Gram-neg inner 1 0 3.3 ± 1.3 86 ± 15 -7.8
3.1.05.03. Peptide YW12 2o0s Designed proteins Bact. Gram-pos cell wall 1 0 3.4 ± 1.3 82 ± 5 -5.5
3.1.20.01. Rho-conotoxin TIA 1ien Conus tulipa (Fish-hunting cone snail) Secreted 1 0 3.4 ± 1.6 73 ± 7 -3.5
3.1.02.01. Third extracellular loop of cholecystokinin A receptor 1hzn Homo sapiens Eukaryo. plasma 1 0 3.4 ± 0.9 81 ± 2 -10.3
3.1.14.01. Kassinin 1myu Kassina senegalensis Secreted 1 0 3.4 ± 1.5 59 ± 16 -4.5
3.1.05.13. Cullin3-derived peptides 2myl Designed proteins Undefined 1 0 3.4 ± 1.2 82 ± 21 -4.4
3.1.24.01. Penaeidin-4d 1xv3 Litopenaeus setiferus (Atlantic white shrimp) Secreted 1 0 3.4 ± 2.7 76 ± 17 -7.8
3.1.11.01. Pancreatic hormone 1ppt Meleagris gallopavo Secreted 1 0 3.5 ± 2.9 90 ± 27 -3.9
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, wild type 2lcy Zaire ebolavirus Viral 1 0 3.5 ± 2.2 59 ± 9 -4.5
3.1.01.05. Proteinase inhibitor, vacuolar targeting peptide (372-397) 1vtp Nicotiana alata (Winged tobacco) Vacuole 1 0 3.5 ± 1.1 87 ± 4 -4.2
3.1.15.01. Leucocin A 1cw6 Leuconostoc gelidum Secreted 1 0 3.6 ± 1.1 90 ± 16 -6.2
3.1.01.01. Kalata-B3/B6 propeptide 1wn8 Oldenlandia affinis Secreted 1 0 3.6 ± 1.2 81 ± 22 -8.4
3.1.20.01. Alpha-conotoxin EI 1k64 Conus ermineus Secreted 1 0 3.6 ± 1.4 78 ± 19 -3.3
3.1.29.01. KR-12 from cathelicidin LL-37 2na3 Homo sapiens Secreted 1 0 3.7 ± 0.7 84 ± 8 -8.3
3.1.29.01. Retro KR-12 2nal Designed proteins Undefined 1 0 3.7 ± 0.5 83 ± 5 -6.1
3.1.02.14. Tumor-associated calcium signal transducer 2, peptide 304-322 2mae Homo sapiens Eukaryo. plasma 1 0 3.7 ± 3.0 82 ± 0 -3.7
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, mutant 1 2mb1 Zaire ebolavirus Viral 1 0 3.8 ± 1.8 53 ± 34 -4.5
3.1.04.03. Viral protein R, peptide 50-82 1bde Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 3.8 ± 1.1 89 ± 24 -6.7
3.1.28.06. Magainin analogue 2 5cgo Designed proteins Undefined 2 0 3.8 ± 0.9 89 ± 2 -10.8
3.1.03.10. Lipid droplet anchoring peptide of CGI-58 5a4h Mus musculus Vesicle 1 0 3.9 ± 1.2 37 ± 7 -7.5
3.1.05.04. Distinctin 1xkm Designed proteins Undefined 2 0 3.9 ± 0.4 87 ± 2 -4.6
3.1.02.01. Second intracellular loop (118-149) of alpha-2A adrenergic receptor 1hod Homo sapiens Eukaryo. plasma 1 0 3.9 ± 4.1 75 ± 3 -7.2
3.1.13.01. Islet amyloid polypeptide, fragment 34-70 2kb8 Homo sapiens Secreted 1 0 3.9 ± 4.2 90 ± 1 -10.2
3.1.13.01. Islet amyloid polypeptide, peptide 38-74 2kj7 Rattus norvegicus Secreted 1 0 3.9 ± 4.3 90 ± 4 -4.2
3.1.02.02. Potassium voltage-gated channel protein Shaker, peptide 378-397 1ho2 Drosophila melanogaster Eukaryo. plasma 1 0 3.9 ± 1.2 88 ± 16 -7.5
3.1.11.02. Glucagon-like peptide 2 2l64 Homo sapiens Secreted 1 0 3.9 ± 0.3 90 ± 5 -10.8
3.1.05.03. LAK160-P10 2l99 Designed proteins Undefined 1 0 3.9 ± 2.6 84 ± 0 -5.0
3.1.30.01. Lactoferrin-based peptide, 39-49 2gmc Homo sapiens Secreted 1 0 3.9 ± 1.7 79 ± 13 -4.6
3.1.11.02. Pituitary adenylate cyclase activating polypeptide (PACAP)-38 2d2p Homo sapiens Secreted 1 0 3.9 ± 4.0 90 ± 0 -6.8
3.1.03.01. Myc box-dependent-interacting protein 1, membrane anchor helix (peptide 1-33) 2rnd Homo sapiens Eukaryo. plasma 1 0 4.0 ± 0.4 85 ± 2 -8.4
3.1.07.02. Juxtamembrane peptide (665-683) of protein gp41 1jau Human immunodeficiency virus type 1 Endosome 1 0 4.0 ± 4.2 86 ± 2 -8.0
3.1.11.01. Peptide YY 2dez Homo sapiens Secreted 1 0 4.0 ± 0.2 84 ± 2 -5.9
3.1.04.07. Peptide (2-25) of antifreeze protein Afp1 2lq0 Glaciozyma antarctica Undefined 1 0 4.0 ± 3.8 85 ± 2 -9.5
3.1.27.01. Pardaxin 2kns Pardachirus marmoratus Secreted 1 0 4.0 ± 0.7 84 ± 7 -11.1
3.1.20.01. Conotoxin pc16a 2ler Conus pictus Secreted 1 0 4.0 ± 1.0 64 ± 7 -4.1
3.1.11.02. Vasoactive intestinal peptide 2rrh Homo sapiens Secreted 1 0 4.1 ± 0.3 79 ± 9 -5.7
3.1.28.02. Neuromedin-C 2n0h Homo sapiens Secreted 1 0 4.1 ± 1.6 82 ± 18 -3.1
3.1.07.01. Fusion peptide of spike glycoprotein (758-820) 5xjk Human SARS coronavirus Endosome 1 0 4.1 ± 1.4 82 ± 2 -10.9
3.1.21.09. Cytotoxic linear peptide IsCT 1t51 Opisthacanthus madagascariensis Secreted 1 0 4.1 ± 0.6 87 ± 11 -10.5
3.1.15.01. Leucocin A, linear analogue 2ljt Leuconostoc gelidum Secreted 1 0 4.2 ± 2.8 81 ± 1 -6.6
3.1.20.01. alpha-conotoxin PNIB 1akg Conus pennaceus Secreted 1 0 4.2 ± 1.4 42 ± 19 -5.9
3.1.12.01. Sarafotoxin-I3 2lde Atractaspis microlepidota microlepidota Secreted 1 0 4.2 ± 3.6 86 ± 8 -2.8
3.1.08.01. Ice-structuring protein SS-3 1y04 Myoxocephalus scorpius Secreted 1 1 4.2 ± 3.8 90 ± 5 -6.7
3.1.04.04. Peptide of huntigtin, 1-17 2ld2 Homo sapiens Eukaryo. plasma 1 0 4.2 ± 0.6 90 ± 4 -9.3
3.1.28.01. Dermaseptin-4 2dd6 Phyllomedusa sauvagei (Sauvage's leaf frog) Secreted 1 0 4.2 ± 1.6 76 ± 6 -7.0
3.1.07.02. Juxtamembrane peptide (684-719) of protein gp41 2kzq Hepatitis C virus Endosome 1 0 4.3 ± 3.3 88 ± 0 -9.9
3.1.23.01. Meucin-24 2kfe Mesobuthus eupeus Secreted 1 0 4.3 ± 3.5 82 ± 2 -7.5
3.1.11.02. Exendin-4-conotoxin chimera 2naw Designed proteins Secreted 1 0 4.3 ± 1.4 69 ± 8 -2.7
3.1.12.01. Endothelin-1 1edn Homo sapiens Secreted 1 0 4.3 ± 1.2 71 ± 25 -5.4
3.1.15.03. Bacteriocin peptide plantaricin E (PlnE) 2jui Lactobacillus plantarum Secreted 1 0 4.3 ± 4.2 79 ± 4 -5.0
3.1.28.02. Neuromedin-B 1c98 Homo sapiens Secreted 1 0 4.3 ± 1.8 77 ± 11 -3.8
3.1.28.09. Pseudin-2, structure 2 2ncx Pseudis paradoxa Secreted 1 0 4.4 ± 4.4 85 ± 13 -9.2
3.1.21.08. Moricin 1x22 Spodoptera litura Secreted 1 0 4.4 ± 1.1 70 ± 5 -9.2
3.1.15.05. LsbB 2mlu Lactococcus lactis Secreted 1 0 4.4 ± 4.1 89 ± 2 -6.0
3.1.02.01. Beta-1 adrenergic receptor, peptide 345-359 1dep Meleagris gallopavo Eukaryo. plasma 1 0 4.4 ± 1.2 76 ± 16 -8.3
3.1.28.03. Maximin-4 2mhw Bombina maxima Secreted 1 0 4.4 ± 1.0 75 ± 3 -6.3
3.1.11.02. Glucagon 1kx6 Bos taurus Secreted 1 0 4.4 ± 2.0 70 ± 0 -6.4
3.1.04.06. Amyloidogenic peptide (248-286) of prostatic acid phosphatase 2l3h Homo sapiens Eukaryo. plasma 1 0 4.5 ± 2.7 86 ± 0 -4.2
3.1.14.01. Tachykinin-4 2moc Homo sapiens Secreted 1 0 4.6 ± 0.6 75 ± 5 -7.7
3.1.28.01. Dermatistinctin K 2k9b Phyllomedusa distincta Secreted 1 0 4.6 ± 1.0 90 ± 10 -7.0
3.1.03.11. Toll/interleukin-1 receptor domain-containing adapter protein 5t7q Homo sapiens Eukaryo. plasma 1 0 4.6 ± 1.3 75 ± 6 -9.3
3.1.02.02. S5P linker peptide (570-611) of HERG K+ channel 1ujl Homo sapiens Eukaryo. plasma 1 0 4.6 ± 0.3 89 ± 7 -7.6
3.1.02.12. Juxtamembrane peptide of epidermal growth factor receptor 1z9i Homo sapiens Eukaryo. plasma 1 0 4.7 ± 1.6 78 ± 5 -7.1
3.1.28.08. Ocellatin-LB1 5u9v Leptodactylus labyrinthicus Secreted 1 0 4.7 ± 1.4 76 ± 4 -6.6
3.1.31.01. Dermcidin, structure 1 2ksg Homo sapiens Secreted 1 0 4.7 ± 1.4 45 ± 6 -7.0
3.1.31.01. Dermcidin, crystal structure 2ymk Homo sapiens Secreted 1 0 4.8 ± 1.3 90 ± 0 -31.0
3.1.10.01. Competence-stimulating peptide type 1 2a1c Streptococcus pneumoniae Secreted 1 0 4.8 ± 0.9 85 ± 20 -7.7
3.1.06.01. Apolipoprotein E, peptide 281-304 1oef Homo sapiens Undefined 1 0 4.8 ± 0.9 88 ± 19 -5.5
3.1.13.01. Proadrenomedullin N-20 terminal peptide 2fly Homo sapiens Secreted 1 0 4.8 ± 4.0 88 ± 2 -7.5
3.1.15.01. Enterocin-HF 2n4k Enterococcus faecium Secreted 1 0 4.8 ± 3.5 82 ± 4 -4.8
3.1.29.03. Prophenin-1 2i1d Sus scrofa Secreted 1 0 4.8 ± 1.9 70 ± 35 -5.9
3.1.02.08. High affinity copper uptake protein 1, peptide 156-179 2ls4 Homo sapiens Eukaryo. plasma 1 0 4.9 ± 0.7 82 ± 10 -6.5
3.1.02.10. Transmembrane emp24 domain-containing protein 10, peptide 207-219 1m23 Oryctolagus cuniculus Golgi 1 0 4.9 ± 3.2 66 ± 3 -6.9
3.1.21.11. HYL-20 peptide 5mmk Hylaeus signatus Secreted 1 0 4.9 ± 2.8 81 ± 8 -8.8
3.1.12.01. Sarafotoxin-B 1srb Atractaspis engaddensis (Israeli burrowing asp) Secreted 1 0 4.9 ± 1.9 62 ± 10 -4.1
3.1.07.02. Juxtamembrane peptide (662-683) of protein gp160 4g6f Human immunodeficiency virus type 1 Endosome 1 0 4.9 ± 1.4 86 ± 0 -5.0
3.1.11.02. Glucagon analog 1bh0 Homo sapiens Secreted 1 0 4.9 ± 4.2 78 ± 2 -6.1
3.1.05.03. LAK160-P12 2l9a Designed proteins Undefined 1 0 4.9 ± 3.1 87 ± 1 -6.7
3.1.28.09. Pseudin-2, structure 1 2ncy Pseudis paradoxa Secreted 1 0 4.9 ± 3.0 77 ± 5 -5.8
3.1.05.03. Glycosaminoglycan-binding (KYE) peptide 2ncw Designed proteins Undefined 1 0 5.0 ± 0.4 84 ± 6 -10.1
3.1.29.01. Cathelicidin-1 2amn Gallus gallus Secreted 1 0 5.0 ± 3.3 68 ± 4 -8.7
3.1.05.03. WYHRLSHLHSRLQD 5mxt Designed proteins Undefined 1 0 5.0 ± 0.8 77 ± 10 -6.3
3.1.05.03. GLFDIVKKVVGALG 5mxl Designed proteins Undefined 1 0 5.0 ± 0.4 86 ± 6 -7.8
3.1.04.02. Major prion protein, peptide 110-136 2lbg Homo sapiens Eukaryo. plasma 1 0 5.0 ± 7.0 86 ± 1 -9.3
3.1.07.05. Nonstructural protein 5a 2ajo Bovine viral diarrhea virus Endoplasm. reticulum 1 0 5.0 ± 1.0 86 ± 15 -11.8
3.1.21.01. Cecropin B analogue 2igr Hyalophora cecropia (Cecropia moth) Secreted 1 0 5.1 ± 3.6 87 ± 0 -11.3
3.1.05.03. Lavracin 2n8d Designed proteins Undefined 1 0 5.1 ± 1.2 89 ± 13 -5.7
3.1.20.01. alpha-conotoxin auIB 1dg2 Conus aulicus Secreted 1 0 5.1 ± 1.7 89 ± 16 -4.9
3.1.14.01. Neuropeptide K 2b19 Homo sapiens Secreted 1 0 5.1 ± 4.3 46 ± 8 -5.7
3.1.11.01. Neuropeptide Y-pancreatic polypeptide hybrid 1tz4 Sus scrofa Secreted 1 0 5.1 ± 1.0 88 ± 8 -6.1
3.1.01.06. Protein PB1-F2, mitochondrial targeting peptide (50-87) 2hn8 Influenza virus Mitochon. inner 1 0 5.1 ± 3.8 86 ± 1 -10.9
3.1.11.01. Peptide YY 1ru5 Sus scrofa Secreted 1 0 5.1 ± 1.2 83 ± 3 -5.3
3.1.11.02. Glucagon analog, lipidated 2m5p Homo sapiens Secreted 1 0 5.2 ± 0.6 85 ± 4 -6.0
3.1.21.02. Mastoparan 2czp Vespa xanthoptera Secreted 1 0 5.2 ± 1.6 88 ± 16 -9.8
3.1.29.01. Crotalicidin 2mwt Crotalus durissus terrificus Secreted 1 0 5.2 ± 2.4 86 ± 1 -8.6
3.1.29.03. Prophenin-1 analogues 2i1e Sus scrofa Secreted 1 0 5.2 ± 1.0 53 ± 7 -7.5
3.1.20.01. alpha-conotoxin PNI1 1pen Conus pennaceus Secreted 1 0 5.2 ± 1.7 27 ± 19 -3.8
3.1.20.01. Alpha4/6-conotoxin TxIC 2m3i Conus lividus Secreted 1 0 5.3 ± 1.0 77 ± 10 -4.9
3.1.17.01. Antimicrobial peptide HP 1p0l Helicobacter pylori Secreted 1 0 5.3 ± 0.6 79 ± 9 -10.5
3.1.07.04. Juxtamembrane peptide of hepatis C virus E1 glycoprotein (314-342) 2knu Hepatitis C virus Endosome 1 0 5.3 ± 0.9 82 ± 6 -5.9
3.1.11.02. Glucagon 1gcn Sus scrofa Secreted 1 0 5.3 ± 1.0 78 ± 12 -6.6
3.1.07.05. Nonstructural protein 5a, segment 1973-2003 1r7g Human hepatitis C virus Endoplasm. reticulum 1 0 5.3 ± 0.9 90 ± 5 -15.1
3.1.04.02. Major prion protein, peptide 173-195 2iv5 Homo sapiens Eukaryo. plasma 1 0 5.3 ± 4.1 83 ± 17 -3.5
3.1.15.04. Bacteriocin plantaricin J (PlnJ) 2khg Lactobacillus plantarum Secreted 1 0 5.4 ± 4.0 72 ± 2 -9.0
3.1.26.01. Pleurocidin 1z64 Pseudopleuronectes americanus Secreted 1 0 5.4 ± 1.3 87 ± 18 -12.8
3.1.29.02. Indolicidin, with P->A substitution 1hr1 Designed proteins Undefined 1 0 5.4 ± 4.0 84 ± 9 -8.3
3.1.07.02. Envelope glycoprotein gp41 2x7r Human immunodeficiency virus type 1 Viral 3 0 5.5 ± 1.1 0 ± 10 -10.9
3.1.13.01. Calcitonin 2jxz Homo sapiens Secreted 1 0 5.5 ± 1.1 72 ± 6 -11.5
3.1.05.03. Antimicrobial peptide PaDBS1R1 2n9r Designed proteins Undefined 1 0 5.6 ± 1.0 83 ± 6 -8.3
3.1.07.05. Nonstructural protein 4b, segment 1751-1780 2jxf Hepatitis C virus Endoplasm. reticulum 1 0 5.6 ± 3.6 85 ± 2 -10.6
3.1.21.02. Anoplin 2mjq Anoplius samariensis Secreted 1 0 5.6 ± 1.1 85 ± 8 -8.4
3.1.21.06. Stomoxyn 1zrx Stomoxys calcitrans (Stable fly) Secreted 1 0 5.7 ± 0.0 80 ± 0 -12.3
3.1.03.04. Anchor helix of protein yopD (peptide 278-300) 1kdl Yersinia pseudotuberculosis Eukaryo. plasma 1 0 5.7 ± 0.8 86 ± 12 -5.0
3.1.07.01. Fusion peptide (507-560) of ebolavirus glycoprotein GP2, mutant 2 2m5f Zaire ebolavirus Viral 1 0 5.7 ± 1.7 29 ± 30 -5.2
3.1.05.11. ALPS-23 peptide 2m0w Designed proteins Undefined 1 0 5.7 ± 0.5 72 ± 6 -9.4
3.1.29.01. Ovispirin-1 1hu5 Ovis aries Secreted 1 0 5.7 ± 0.5 81 ± 1 -9.2
3.1.14.01. Neurokinin B 1p9f Homo sapiens Secreted 1 0 5.8 ± 1.2 89 ± 18 -6.8
3.1.16.01. Lactococcin-G subunit alpha 2jpj Lactococcus lactis Secreted 1 0 5.8 ± 2.9 77 ± 3 -5.9
3.1.07.01. Fusion peptide (524-539) of ebolavirus glycoprotein GP2 2rlj Zaire ebolavirus Viral 1 0 5.8 ± 1.8 84 ± 6 -6.8
3.1.28.04. Phylloseptin-2 2jpy Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 5.8 ± 1.3 86 ± 4 -15.2
3.1.01.02. Leader peptide of patellamide protein 2kya Prochloron didemni Secreted 1 0 5.8 ± 0.5 86 ± 4 -8.8
3.1.21.08. Moricin 2jr8 Manduca sexta Secreted 1 0 5.9 ± 1.6 75 ± 3 -11.5
3.1.05.01. Antimicrobial peptide RP-1 2rlg Designed proteins Undefined 1 0 5.9 ± 4.2 75 ± 4 -5.0
3.1.02.01. C-terminal helix of MCP-1 receptor 2mlo Homo sapiens Eukaryo. plasma 1 0 6.0 ± 1.6 86 ± 8 -10.1
3.1.07.02. Membrane proximal external helix of HIV-1 gp41 (656-683) 2m8o Human immunodeficiency virus type 1 Viral 1 0 6.0 ± 5.2 90 ± 4 -5.0
3.1.04.05. Lactotransferrin peptide (287-303) 2md1 Bos taurus Secreted 1 0 6.0 ± 1.0 71 ± 9 -7.3
3.1.21.08. Moricin 1kv4 Bombyx mori Secreted 1 0 6.1 ± 0.6 77 ± 14 -10.3
3.1.28.08. Ocellatin-F1 5ua8 Leptodactylus labyrinthicus Secreted 1 0 6.1 ± 0.8 71 ± 7 -10.0
3.1.07.02. Juxtamembrane peptide (636-662) of protein gp160 2me3 Human immunodeficiency virus type 1 Endosome 1 0 6.1 ± 0.4 81 ± 7 -12.4
3.1.28.06. Magainin analogue 1 5cgn Designed proteins Undefined 2 0 6.1 ± 2.7 88 ± 6 -14.0
3.1.29.01. LL-37-derived peptide 2l5m Designed proteins Undefined 1 0 6.1 ± 1.0 89 ± 7 -9.7
3.1.13.01. Calcitonin-1 2glg Oncorhynchus keta (Chum salmon) Secreted 1 0 6.1 ± 0.8 84 ± 4 -11.7
3.1.13.01. Islet amyloid polypeptide, fragment 34-70, alternative structure 2l86 Homo sapiens Secreted 1 0 6.2 ± 0.8 88 ± 7 -9.6
3.1.05.05. Anticoccidial peptide PW2 2jq2 Designed proteins Undefined 1 0 6.2 ± 2.3 67 ± 36 -4.5
3.1.07.04. Envelope glycoprotein E1, heterodimerization peptide (350-370) 1emz Hepatitis C virus Viral 1 0 6.2 ± 0.2 86 ± 9 -8.5
3.1.21.04. Oxyopinin-4a 2l3i Oxyopes takobius (Lynx spider) Secreted 1 0 6.2 ± 1.2 71 ± 10 -6.8
3.1.18.02. Phenol-soluble modulin beta-2 5kgz Staphylococcus aureus Secreted 1 0 6.2 ± 2.5 55 ± 7 -6.2
3.1.07.02. Juxtamembrane peptide (659-685) of protein gp160 2fx7 Human immunodeficiency virus type 1 Endosome 1 0 6.2 ± 1.0 73 ± 7 -8.0
3.1.04.07. Peptide (70-94) of antifreeze protein Afp1 2lq1 Glaciozyma antarctica Undefined 1 0 6.2 ± 4.3 87 ± 1 -8.8
3.1.12.01. Endothelin-1 3cmh Rattus norvegicus Secreted 1 0 6.3 ± 3.9 72 ± 40 -4.8
3.1.02.01. Fourth intracellular loop of CB1 cannabinoid receptor 2mz2 Designed proteins Eukaryo. plasma 1 0 6.3 ± 1.2 80 ± 6 -7.4
3.1.07.03. Hemagglutinin, fusion peptide 346-365, G1S 1xop Influenza virus Viral 1 0 6.3 ± 0.5 70 ± 13 -11.0
3.1.11.02. Glucagon-like peptide-1 receptor agonists 2n08 Designed proteins Undefined 1 0 6.3 ± 1.3 45 ± 10 -5.4
3.1.11.02. Gastric inhibitory polypeptide, complex with N-terminal domain of GPCR 2qkh Homo sapiens Secreted 2 0 6.3 ± 3.2 64 ± 23 -5.9
3.1.03.02. Serine/threonine-protein kinase TOR1, FATC domain 2kit Saccharomyces cerevisiae Vacuole 1 0 6.3 ± 1.0 87 ± 18 -6.4
3.1.33.01. Stage V sporulation protein M 2mvh Bacillus subtilis Vacuole 1 0 6.3 ± 1.0 90 ± 4 -9.9
3.1.11.06. Parathyroid hormone-related peptide, structure 1 1bzg Homo sapiens Secreted 1 0 6.4 ± 2.2 54 ± 18 -6.4
3.1.11.04. Orexin-A 1wso Homo sapiens Secreted 1 0 6.4 ± 1.7 72 ± 14 -5.5
3.1.04.01. Protein STE5, peptide 44-67 2kgn Saccharomyces cerevisiae Eukaryo. plasma 1 0 6.4 ± 0.9 84 ± 7 -9.8
3.1.07.05. Nonstructural protein 4b, segment 1716-1755 2lvg Hepatitis C virus Viral 1 0 6.4 ± 0.7 82 ± 8 -11.4
3.1.14.01. Uperolein 2gfr Uperoleia rugosa (Wrinkled toadlet) Secreted 1 0 6.4 ± 1.2 88 ± 9 -8.2
3.1.01.01. Varv peptide A/Kalata-B1 propeptide 1wn4 Viola odorata Secreted 1 0 6.4 ± 1.1 81 ± 14 -7.2
3.1.28.04. Phylloseptin-3 2jq1 Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 6.4 ± 0.8 74 ± 9 -9.5
3.1.11.01. Neuropeptide Y analogue 1icy Sus scrofa Secreted 1 0 6.4 ± 0.5 69 ± 6 -8.1
3.1.06.02. Amphipathic alpha-helix of apolipoprotein 2irg Designed proteins Undefined 1 0 6.4 ± 1.7 83 ± 15 -12.1
3.1.06.02. Class A amphipathic helical peptide 2fq5 Designed proteins Undefined 1 0 6.5 ± 1.4 78 ± 6 -8.8
3.1.15.01. Carnobacteriocin B2 1cw5 Carnobacterium maltaromaticum Secreted 1 0 6.5 ± 0.3 89 ± 5 -9.9
3.1.21.01. Cecropin (1-7)-melittin (2-9) hybrid 2jmy Designed proteins Undefined 1 0 6.5 ± 3.3 77 ± 7 -6.1
3.1.21.02. Mastoparan-L 1d7n Vespula lewisii Secreted 1 0 6.5 ± 1.7 82 ± 16 -7.5
3.1.04.09. Membrane-permeabilizing peptide (654-676) from hemocyanin 2n1c Litopenaeus vannamei (Whiteleg shrimp) Undefined 1 0 6.5 ± 1.3 90 ± 9 -6.3
3.1.29.02. Indolicidin analogue (cathelicidin-4) 1qx9 Bos taurus Secreted 1 0 6.6 ± 1.9 46 ± 15 -7.7
3.1.05.03. Peptide F 1pef Designed proteins Undefined 1 0 6.6 ± 1.3 85 ± 10 -7.8
3.1.16.01. Lactococcin-G subunit beta 2jpm Lactococcus lactis Secreted 1 0 6.7 ± 3.3 86 ± 0 -11.2
3.1.21.02. Decoralin 2n9a Oreumenes decoratus Secreted 1 0 6.7 ± 1.7 86 ± 11 -8.9
3.1.07.02. Juxtamembrane peptide (662-683) of protein gp41 2pv6 Human immunodeficiency virus type 1 Endosome 1 0 6.7 ± 0.6 82 ± 2 -13.5
3.1.02.13. Regulatory domain of brain carnitine palmitoyltransferase 2m76 Homo sapiens Mitochon. outer 1 0 6.7 ± 1.0 88 ± 16 -6.9
3.1.07.01. Fusion peptide of spike glycoprotein (1185-1201) 2run Human SARS coronavirus Endosome 1 0 6.8 ± 4.0 74 ± 7 -10.7
3.1.14.01. Neurokinin A 1n6t Gallus gallus Secreted 1 0 6.8 ± 1.2 60 ± 17 -4.9
3.1.02.02. Sodium channel protein type 3 subunit alpha, TMH 2 1qg9 Rattus norvegicus Eukaryo. plasma 1 0 6.8 ± 0.4 86 ± 3 -9.0
3.1.05.08. MSI-594 derived peptide MSI-594-F5A 2l36 Designed proteins Undefined 1 0 6.9 ± 7.0 79 ± 3 -8.3
3.1.03.03. Anticancer peptide designed based on the helix of phosphotransferase IIA 1vm2 Designed proteins Undefined 1 0 7.0 ± 1.8 78 ± 15 -12.0
3.1.15.05. Enterocin K1 5l82 Enterococcus faecium Secreted 1 0 7.0 ± 3.6 27 ± 6 -6.3
3.1.02.15. Glutamate receptor ionotropic, NMDA 1, TMH 2 2nr1 Homo sapiens Eukaryo. plasma 1 0 7.0 ± 3.7 84 ± 0 -12.5
3.1.28.08. Ocellatin-LB2 5ua7 Leptodactylus labyrinthicus Secreted 1 0 7.0 ± 4.4 78 ± 2 -11.1
3.1.07.02. Juxtamembrane peptide (651-677) of protein gp160 2me2 Human immunodeficiency virus type 1 Endosome 1 0 7.0 ± 1.1 82 ± 7 -13.1
3.1.29.01. Cathelicidin-6 2ket Bos taurus Secreted 1 0 7.1 ± 0.7 82 ± 3 -13.6
3.1.28.04. Temporin-A 2maa Rana temporaria Secreted 1 0 7.2 ± 0.5 66 ± 7 -8.4
3.1.04.03. Viral protein R, peptide 52-96, dimer, different strain 1x9v Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.2 ± 0.7 86 ± 4 -8.6
3.1.28.08. Ocellatin-K1 5u9x Leptodactylus knudseni Secreted 1 0 7.4 ± 0.2 77 ± 4 -11.8
3.1.30.01. Lactoferricin peptide (36-59) 5id5 Sus scrofa Secreted 1 0 7.4 ± 1.0 87 ± 9 -6.2
3.1.29.01. Antimicrobial protein CAP18, segment 135-166 1lyp Oryctolagus cuniculus Secreted 1 0 7.4 ± 1.0 87 ± 9 -15.6
3.1.04.03. Viral protein R, peptide 34-51 1kzt Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 7.4 ± 0.6 77 ± 7 -10.3
3.1.20.01. Alpha-conotoxin BuIA 2i28 Conus bullatus (Bubble cone) Secreted 1 0 7.4 ± 2.2 68 ± 9 -4.6
3.1.07.05. Nonstructural protein 2a, segment 1194-1221 2m0s Dengue virus Endoplasm. reticulum 1 0 7.4 ± 3.6 79 ± 1 -7.1
3.1.02.02. Voltage sensor of calcium-activated potassium channel 2k44 Homo sapiens Eukaryo. plasma 1 0 7.5 ± 3.0 54 ± 4 -9.8
3.1.21.10. Pilosulin-1 5x3l Myrmecia pilosula Secreted 1 0 7.6 ± 3.2 82 ± 7 -8.5
3.1.04.10. TAR DNA-binding protein 43, peptide 307-349 2n2c Homo sapiens Nuclear inner 1 0 7.7 ± 0.7 89 ± 6 -13.4
3.1.07.02. Juxtamembrane peptide (657-683) of protein gp160 2me1 Human immunodeficiency virus type 1 Endosome 1 0 7.7 ± 3.8 82 ± 1 -15.0
3.1.21.01. Papiliocin 2la2 Papilio xuthus Secreted 1 0 7.8 ± 2.0 62 ± 4 -7.4
3.1.28.04. Esculentin-1A 2n6m Pelophylax esculentus Secreted 1 0 7.9 ± 0.4 67 ± 5 -7.9
3.1.07.05. Nonstructural protein, membrane-bound domain 1fw5 Semiliki forest virus Endosome 1 0 7.9 ± 1.5 73 ± 17 -10.2
3.1.11.01. Neuropeptide Y 1ron Homo sapiens Secreted 1 0 7.9 ± 1.6 74 ± 10 -8.6
3.1.07.02. Juxtamembrane peptide (671-697) of protein gp160 2me4 Human immunodeficiency virus type 1 Endosome 1 0 7.9 ± 2.9 81 ± 4 -14.0
3.1.03.09. Peptide (2-11) of ADP-ribosylation factor 6, in aqueous solution 2bao Homo sapiens Eukaryo. plasma 1 0 8.0 ± 1.2 82 ± 8 -5.5
3.1.07.03. Hemagglutinin, peptide 330-349, F9A 2jrd Influenza virus Viral 1 0 8.1 ± 4.0 71 ± 5 -6.8
3.1.19.01. Antiamoebin I 1joh Emercelliopsis sp. Secreted 1 0 8.1 ± 0.8 82 ± 5 -11.7
3.1.02.11. Methyl-accepting chemotaxis protein II 2l9g Escherichia coli Bact. Gram-neg inner 1 0 8.1 ± 4.2 75 ± 0 -11.7
3.1.29.01. Cathelicidin LL-37 2k6o Homo sapiens Secreted 1 0 8.1 ± 0.4 86 ± 8 -15.7
3.1.21.07. Cupiennin-1a (M-ctenitoxin-Cs1a) 2k38 Cupiennius salei (Wandering spider) Secreted 1 0 8.1 ± 4.0 77 ± 9 -5.1
3.1.10.01. Competence stimulating peptide 2i2h Streptococcus mutants Secreted 1 0 8.2 ± 0.5 74 ± 7 -12.5
3.1.07.01. Fusion peptide of E1 envelope glycoprotein (84-101) 2rsw Chikungunya virus Endosome 1 0 8.3 ± 0.6 57 ± 7 -6.9
3.1.07.02. Paramyxovirus sv5 fusion protein core 1svf Simian virus 5 Viral 6 0 8.4 ± 0.9 0 ± 11 -10.7
3.1.14.01. Neuropeptide gamma 2mce Oryctolagus cuniculus Secreted 1 0 8.4 ± 1.4 60 ± 10 -6.1
3.1.25.01. Latarcin-2a (M-zodatoxin-Lt2a) 2g9p Lachesana tarabaevi (Spider) Secreted 1 0 8.5 ± 1.4 77 ± 9 -6.4
3.1.28.03. Bombinin-H5 2ap8 Bombina variegata (Yellow-bellied toad) Secreted 1 0 8.6 ± 4.2 77 ± 3 -10.6
3.1.14.01. Scyliorhinin-1 2nou Scyliorhinus canicula (Small-spotted catshark) Secreted 1 0 8.6 ± 1.4 81 ± 10 -9.1
3.1.09.01. ICP47 protein, active domain (1-34) 1qlo Human herpesvirus Endoplasm. reticulum 1 0 8.6 ± 0.8 58 ± 8 -10.2
3.1.11.03. Motilin 1lbj Homo sapiens Secreted 1 0 8.6 ± 1.6 51 ± 18 -4.9
3.1.28.02. Alyteserin-1C 2l5r Alytes obstetricans Secreted 1 0 8.7 ± 4.1 81 ± 0 -14.1
3.1.15.03. Bacteriocin peptide plantaricin F (PlnF) 2rlw Lactobacillus plantarum Secreted 1 0 8.7 ± 4.4 79 ± 5 -11.7
3.1.07.03. Antimicrobial peptide derived from hemagglutinin 2l24 Influenza virus Undefined 1 0 8.7 ± 1.3 75 ± 10 -12.6
3.1.07.01. Fusion peptide (510-532) of protein gp41 2pjv Human immunodeficiency virus type 1 Endosome 1 0 8.7 ± 3.8 64 ± 4 -10.9
3.1.28.04. Gaegurin-4 2g9l Glandirana rugosa (Japanese wrinkled frog) Secreted 1 0 8.9 ± 4.0 71 ± 3 -9.6
3.1.05.10. WALP19 - Pro8 peptide 2lco Designed proteins Undefined 1 0 9.0 ± 0.4 85 ± 4 -15.0
3.1.15.02. Plantaricin-A 1ytr Lactobacillus plantarum Secreted 1 0 9.0 ± 0.5 78 ± 10 -9.4
3.1.07.03. Hemagglutinin, fusion peptide 346-365, wild type 1ibn Influenza virus Viral 1 0 9.1 ± 1.2 67 ± 7 -8.0
3.1.05.06. Transportan 1smz Designed proteins Undefined 1 0 9.1 ± 0.8 87 ± 7 -8.9
3.1.07.02. Ebola virus envelope glycoprotein, 632-676 5t42 Zaire ebolavirus Viral 1 0 9.1 ± 3.6 71 ± 0 -16.4
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 436-456 1bts Homo sapiens Eukaryo. plasma 1 0 9.2 ± 0.3 84 ± 2 -14.8
3.1.07.09. Membrane fusion protein p15 2mns Baboon orthoreovirus Eukaryo. plasma 1 0 9.3 ± 7.0 86 ± 4 -9.4
3.1.18.02. Phenol-soluble modulin alpha 3 peptide 5kgy Staphylococcus aureus Secreted 1 0 9.4 ± 1.0 73 ± 7 -17.3
3.1.18.02. Phenol-soluble modulin alpha-1 5khb Staphylococcus aureus Secreted 1 0 9.4 ± 0.8 71 ± 4 -12.7
3.1.29.03. Tritrpticin 1d6x Sus scrofa Secreted 1 0 9.4 ± 2.6 81 ± 38 -8.1
3.1.07.06. NS2 protease, segment 836-868 of polyprotein 2kwt Hepatitis C virus Endoplasm. reticulum 1 0 9.5 ± 3.6 81 ± 3 -15.7
3.1.28.04. Phylloseptin-1 2jq0 Phyllomedusa hypochondrialis (Orange-legged leaf frog) Secreted 1 0 9.5 ± 1.4 76 ± 7 -13.5
3.1.04.03. Viral protein R, peptide 59-86 1dsk Human immunodeficiency virus type 1 Eukaryo. plasma 1 0 9.5 ± 0.4 65 ± 6 -11.7
3.1.28.05. Aurein 1.2 1vm5 Litoria aurea Secreted 1 0 9.5 ± 1.8 63 ± 14 -9.7
3.1.03.05. Anchor helix of 1,2-diacylglycerol 3-glucosyltransferase 1z2t Acholeplasma laidlawii Bact. Gram-pos plas. 1 0 9.6 ± 1.6 90 ± 4 -13.7
3.1.19.01. Chrysospermin C 1ee7 Apiocrea chrysosperma Secreted 1 0 9.8 ± 2.3 82 ± 12 -12.2
3.1.07.01. Fusion peptide of spike glycoprotein (983-887) 2ruo Human SARS coronavirus Endosome 1 0 9.9 ± 4.0 72 ± 6 -9.0
3.1.28.05. Peptoid analogue of maculatin 2mmj Litoria genimaculata Secreted 1 0 10.0 ± 4.6 73 ± 3 -13.1
3.1.07.01. Fusion peptide (512-541) of protein gp41 2ari Human immunodeficiency virus type 1 Endosome 1 0 10.0 ± 1.0 88 ± 9 -16.1
3.1.28.06. Magainin 2, Ala-analogue 4mgp Designed proteins Secreted 1 0 10.0 ± 4.1 79 ± 2 -15.1
3.1.28.06. Magainin 2 2mag Xenopus laevis Secreted 1 0 10.1 ± 0.9 81 ± 14 -13.7
3.1.25.01. Latarcin-1 (M-zodatoxin-Lt1a) 2pco Lachesana tarabaevi (Spider) Secreted 1 0 10.1 ± 0.8 77 ± 6 -9.4
3.1.07.08. Peptide of outer capsid glycoprotein VP7 (266-326) 2lm7 Rotavirus A Endoplasm. reticulum 1 0 10.2 ± 1.5 76 ± 0 -13.6
3.1.07.03. Hemagglutinin, fusion peptide 346-365, H1 subtype 2kxa Influenza virus Viral 1 0 10.3 ± 1.9 84 ± 13 -14.5
3.1.19.01. Trichotoxin a50e 1m24 Trichoderma viride Secreted 1 0 10.4 ± 1.8 75 ± 32 -14.3
3.1.28.04. Ranatuerin-2csa 2k10 Rana temporaria Secreted 1 0 10.4 ± 1.2 74 ± 5 -14.3
3.1.05.09. Histidine-rich peptide LAH4 2kjn Designed proteins Undefined 1 0 10.5 ± 6.3 89 ± 2 -10.2
3.1.26.01. Piscidin 1 2ojm Morone saxatilis Secreted 1 0 10.6 ± 1.0 82 ± 13 -16.3
3.1.19.01. Alamethicin 1amt Trichoderma viride Secreted 1 0 10.9 ± 2.9 74 ± 13 -17.1
3.1.07.03. Hemagglutinin, fusion peptide 346-365, G13A 2l4g Influenza virus Viral 1 0 11.1 ± 0.4 73 ± 4 -10.4
3.1.07.01. Fusion peptide of spike glycoprotein (772-787) 2rum Human SARS coronavirus Endosome 1 0 11.1 ± 1.1 57 ± 13 -10.8
3.1.03.09. Peptide (2-11) of ADP-ribosylation factor 6, in micelle 2bau Homo sapiens Eukaryo. plasma 1 0 11.2 ± 0.9 22 ± 4 -9.1
3.1.28.07. Hylin-A1 2n0o Hypsiboas albopunctatus Secreted 1 0 11.4 ± 0.8 62 ± 4 -15.4
3.1.19.01. Zervamicin IIb 1ih9 Emericellopsis salmosynnemata Secreted 1 0 11.5 ± 2.0 74 ± 10 -12.3
3.1.07.10. Structural peptide 1 of bursal disease virus 2imu Avian infectious bursal disease virus Eukaryo. plasma 1 0 11.6 ± 4.0 76 ± 5 -17.5
3.1.02.06. Band 3 anion transport protein SLC4A1, fragment 405-424 1btq Homo sapiens Eukaryo. plasma 1 0 13.6 ± 2.1 67 ± 11 -22.5
3.1.19.01. Cephaibol A 1ob4 Acremonium tubakii Secreted 1 0 14.1 ± 2.5 58 ± 18 -14.7
3.1.05.02. Self-assembling lipopeptide detergent 3cay Designed proteins Undefined 2 0 14.5 ± 1.3 78 ± 9 -16.4
3.1.19.01. Paracelsin X 4by8 Trichoderma reesei Secreted 1 0 14.6 ± 5.1 60 ± 4 -14.6
3.1.21.03. Melittin 2mlt Apis mellifera Secreted 1 0 15.0 ± 1.0 65 ± 11 -12.0
3.1.19.01. Cephaibol B 1ob6 Acremonium tubakii Secreted 1 0 15.0 ± 5.0 42 ± 17 -15.3
3.1.19.01. Cephaibol C 1ob7 Acremonium tubakii Secreted 1 0 15.0 ± 2.1 55 ± 21 -15.0
3.1.19.01. Samarosporin I 4g13 Samarospora rostrup Secreted 1 0 16.7 ± 1.5 64 ± 14 -15.3
3.1.32.01. Toxic peptide of toxin-antitoxin system (PEPA1) 4b19 Staphylococcus aureus Bact. Gram-pos plas. 1 1 18.8 ± 4.5 62 ± 2 -23.8
3.1.02.01. Peptide 171-197 of parathyroid hormone receptor 1bl1 Homo sapiens Eukaryo. plasma 1 1 20.8 ± 1.2 19 ± 4 -11.5
3.1.07.01. Probable fusion peptide (93-126, 138-160) of protein gp41 2mk3 Human immunodeficiency virus type 1 Endosome 1 2 20.8 ± 0.5 18 ± 1 -13.2
3.1.01.03. Major prion protein, segment 1-30 1skh Bos taurus Eukaryo. plasma 1 1 20.8 ± 6.3 9 ± 5 -10.7
3.1.07.02. Membrane proximal peptide of gp41 (95-121) 2ncs Human immunodeficiency virus type 1 Viral 1 0 20.8 ± 2.0 28 ± 3 -14.6
3.1.27.01. Pardaxin, different conformation 1xc0 Pardachirus marmoratus Secreted 1 1 20.8 ± 5.4 42 ± 2 -9.6
3.1.02.04. V-type proton ATPase subunit a, vacuolar isoform, TMH 7 2jtw Saccharomyces cerevisiae Vacuole 1 1 20.8 ± 6.5 8 ± 7 -7.7
3.1.02.08. High affinity copper uptake protein 1, peptide 132-157 2ls3 Homo sapiens Eukaryo. plasma 1 1 20.8 ± 3.4 43 ± 1 -20.8
3.1.21.01. Aedesin 2mmm Aedes aegypti (Yellowfever mosquito) Secreted 1 1 20.8 ± 0.8 11 ± 3 -12.3
3.1.01.03. N-terminal helix of prion-like protein doppel 1z65 Mus musculus Eukaryo. plasma 1 1 21.0 ± 6.2 8 ± 4 -13.2
3.1.28.07. Hylin-A1 analogs 5j6v Hypsiboas albopunctatus Secreted 1 0 21.2 ± 2.2 33 ± 16 -10.4
3.1.02.05. Glycine receptor alpha-1 subunit, TMH-2 1mot Homo sapiens Eukaryo. plasma 1 1 21.4 ± 1.4 5 ± 3 -14.2
3.1.01.04. Ferredoxin, chloroplastic, transit peptide (1-32) 1fct Chlamydomonas reinhardtii Thylakoid 1 1 21.8 ± 6.7 28 ± 4 -8.4
3.1.07.01. Fusion peptide (671-693) of protein gp41 2mg2 Human immunodeficiency virus type 1 Endosome 1 1 22.2 ± 1.9 34 ± 1 -15.1
3.1.07.05. Nonstructural protein 4b, segment 1938-1965 of polyprotein 2kdr Hepatitis C virus Endoplasm. reticulum 1 1 22.4 ± 2.0 48 ± 2 -19.1
3.1.21.05. Poneratoxin 1g92 Paraponera clavata Secreted 1 0 22.8 ± 8.5 29 ± 7 -12.9
3.1.05.12. Designed transmembrane metallotransporter 4p6j Designed proteins Undefined 2 2 22.8 ± 2.0 3 ± 1 -21.9
3.1.02.07. Na(+)/H(+) antiporter, TMH IV 2m7x Saccharomyces cerevisiae Eukaryo. plasma 1 1 23.0 ± 3.1 9 ± 2 -21.2
3.1.19.01. Zervamicin IIb, transmembrane orientation 1r9u Emericellopsis salmosynnemata Secreted 1 1 23.2 ± 5.4 38 ± 7 -15.0
3.1.02.05. Glycine receptor, alpha-1 subunit, TMH 2+3 1vry Homo sapiens Eukaryo. plasma 1 2 23.2 ± 3.7 5 ± 9 -25.3
3.1.07.06. NS2 protease, segment 845-869 of polyprotein 2mkb Hepatitis GB virus Eukaryo. plasma 1 1 23.2 ± 3.5 30 ± 9 -15.7
3.1.07.06. NS2 protease, segment 810-837 of polyprotein 2jy0 Hepatitis C virus Endoplasm. reticulum 1 1 23.8 ± 2.9 14 ± 4 -11.4
3.1.01.03. N-terminal helix of prion-like protein doppel 2m1j Ovis aries Eukaryo. plasma 1 1 23.8 ± 2.6 31 ± 7 -11.7
3.1.07.05. Nonstructural protein 5b, segment 2982-3011 2n1p Hepatitis C virus Eukaryo. plasma 1 1 24.0 ± 2.5 21 ± 3 -16.1
3.1.21.03. Melittin, with organometallic fragment 2mw6 Apis mellifera Secreted 1 1 24.2 ± 2.4 6 ± 2 -11.8
3.1.02.05. Acetylcholine receptor, subunit delta, TMH 2 1a11 Rattus norvegicus Eukaryo. plasma 1 1 24.4 ± 5.6 17 ± 10 -14.2
3.1.02.08. High affinity copper uptake protein 1, peptide 64-84 2ls2 Homo sapiens Eukaryo. plasma 1 1 25.2 ± 4.2 21 ± 9 -19.0
3.1.07.01. Fusion peptide (517-539) of protein gp41 1p5a Human immunodeficiency virus type 1 Endosome 1 1 25.8 ± 5.5 12 ± 3 -9.3
3.1.02.01. Apelin receptor, peptide 1-55 2low Homo sapiens Eukaryo. plasma 1 1 26.4 ± 5.1 35 ± 2 -16.7
3.1.02.07. Na(+)/H(+) antiporter, TMH IV, fusion construct 2m7w Saccharomyces cerevisiae Eukaryo. plasma 3 3 26.8 ± 0.1 0 ± 2 -5.7
3.1.07.02. gp41-M-MAT, a membrane associated MPER trimer 2lp7 Human immunodeficiency virus type 1 Viral 3 3 26.8 ± 0.9 1 ± 1 -14.2
3.1.19.01. Trichovirin 3sbn Hypocrea rufa Secreted 1 1 26.9 ± 2.3 6 ± 3 -10.1
3.1.07.07. Fusion protein p14, FAST 2lx0 Reptilian orthoreovirus Eukaryo. plasma 1 1 27.4 ± 2.3 17 ± 9 -20.2
3.1.02.01. Cannabinoid receptor 2, TMH 6 2ki9 Homo sapiens Eukaryo. plasma 1 1 28.4 ± 2.2 21 ± 9 -17.0
3.1.05.10. WALP19 - Pro10 peptide 2lcn Designed proteins Undefined 1 1 29.6 ± 6.6 15 ± 7 -12.5
3.1.01.03. Viral core-E1 signal peptide 2lif Hepatitis C virus Viral 1 1 29.6 ± 5.0 19 ± 10 -16.6
3.1.07.06. NS2 protease, segment 869-908 of polyprotein 2kwz Hepatitis C virus Endoplasm. reticulum 1 1 29.8 ± 1.6 59 ± 7 -15.7
3.1.02.05. Acetylcholine receptor, subunit alpha, TMH II 1dxz Torpedo californica Eukaryo. plasma 1 1 29.8 ± 3.6 25 ± 4 -23.1
3.1.02.05. Acetylcholine receptor, subunit beta2, TMH 2 2k59 Homo sapiens Eukaryo. plasma 1 1 30.2 ± 1.9 20 ± 4 -21.0
3.1.02.05. Acetylcholine receptor, subunit beta2, TMH 1 2k58 Homo sapiens Eukaryo. plasma 1 1 30.6 ± 6.0 39 ± 7 -22.0
3.1.19.01. Bergofungin A 5mas Emericellopsis donezkii Secreted 1 1 30.8 ± 1.5 35 ± 20 -13.2
3.1.07.01. Fusion peptide (683-704) of protein gp41 2mg1 Human immunodeficiency virus type 1 Endosome 1 1 30.8 ± 0.5 19 ± 3 -19.4
3.1.07.06. NS2 protease, segment 734-763 of polyprotein 2lzp Hepatitis GB virus Eukaryo. plasma 1 1 30.8 ± 0.5 32 ± 7 -15.6
3.1.02.02. TM peptide (1567-1594) of voltage-gated sodium channel Nav1.4 5jr0 Rattus norvegicus Eukaryo. plasma 1 1 30.8 ± 3.2 39 ± 2 -26.2
3.1.19.01. Gichigamin 4z0w Tolypocladium sp. Secreted 2 2 31.2 ± 4.4 49 ± 7 -34.5
3.1.02.05. Acetylcholine receptor, subunit alpha, TMH 3 3mra Torpedo californica Eukaryo. plasma 1 1 31.6 ± 3.3 35 ± 9 -21.7
3.1.07.02. Transmembrane domain of HIV-1 gp41 (677-716), trimer 5jyn Human immunodeficiency virus type 1 Viral 3 3 36.0 ± 1.6 0 ± 2 -22.0