PDB ID or protein name

Alpha/Beta monotopic/peripheral superfamilies

2.3.001. Transglycosidases (10 families) CL0058 (Pfam)
2.3.002. PLC-like phosphodiesterases (4 families) CL0384 (Pfam)
2.3.003. Alcohol dehydrogenase (1 family) PF08240 (Pfam)
2.3.004. Amidohydrolase superfamily (1 family) CL0034 (Pfam)
2.3.005. FAD/NAD(P)-binding domain (6 families) CL0063 (Pfam)
2.3.006. Alpha/beta-hydrolases (19 families) CL0028 (Pfam)
2.3.007. Peptidase clan MH/MC/MF (1 family) CL0035 (Pfam)
2.3.008. FabD/lysophospholipase-like (2 families) CL0323 (Pfam)
2.3.009. Flavokinase-like nucleotidyl transferase (1 family) CL0119 (Pfam)
2.3.010. UDP-Glycosyltransferase/glycogen phosphorylase (7 families) CL0113 (Pfam)
2.3.011. Chelatase (1 family) CL0043 (Pfam)
2.3.012. Phosphotyrosine protein phosphatases II (1 family)
2.3.013. Thioredoxin-like (6 families) CL0172 (Pfam)
2.3.014. CRAL/TRIO domain (2 families) PF00650 (Pfam)
2.3.015. HIGH-signature proteins, UspA, and PP-ATPase (2 families) CL0039 (Pfam)
2.3.016. P-loop containing nucleoside triphosphate hydrolases (10 families) CL0023 (Pfam)
2.3.017. Common phosphate binding-site TIM barrel superfamily (2 families) CL0036 (Pfam)
2.3.018. CoA-dependent acyltransferases (2 families) 4.C.2 (TCDB) CL0149 (Pfam)
2.3.019. Nucleotide-diphospho-sugar transferases (3 families) CL0110 (Pfam)
2.3.020. CheY-like (1 family) PF01058 (Pfam)
2.3.021. Phosphatase (1 family) CL0031 (Pfam)
2.3.022. Flavoprotein (2 families) CL0042 (Pfam)
2.3.023. Thiolase-like superfamily (1 family) CL0046 (Pfam)
2.3.024. Haloacid dehalogenase-like hydrolase superfamily (2 families) CL0137 (Pfam)
2.3.025. SGNH hydrolase superfamily (2 families) CL0264 (Pfam)
2.3.026. Isocitrate/Isopropylmalate dehydrogenase-like superfamily (1 family) CL0270 (Pfam)
2.3.027. Dihydrofolate reductase-like (1 family) CL0387 (Pfam)
2.3.028. NAD(P)-linked oxidoreductase (1 family)
2.3.029. Putative undecaprenyl diphosphate synthase (1 family) PF01255 (Pfam)
2.3.030. Aspartate/ornithine carbamoyltransferase (1 family) PF02729 (Pfam)
2.3.031. PTS system sorbose subfamily IIB component (1 family) PF03830 (Pfam)
2.3.032. MurD-like peptide ligases (1 family) PF08245 (Pfam)
2.3.033. Glycosyl hydrolase family 85 (1 family) PF03644 (Pfam)
2.3.034. Beta-lactamase-like proteins (1 family) PF00753 (Pfam)
See list of these PDB codes

Alpha/Beta monotopic/peripheral (303 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.3.16.06. ADP-ribosylation factor-like protein 1 1moz Saccharomyces cerevisiae Golgi 2 0 0.7 ± 1.1 90 ± 6 -4.3
2.3.25.02. Lipolytic protein 4rw0 Veillonella parvula Secreted 1 0 0.7 ± 0.7 60 ± 5 -4.0
2.3.06.11. Monoglyceride lipase MGLL, closed ligand-bound conformation 3pe6 Homo sapiens Eukaryo. plasma 1 0 0.9 ± 3.0 54 ± 28 -2.7
2.3.06.19. PHB depolymerase PhaZ7, structure 2 4btv Pseudomonas lemoignei Secreted 1 0 1.0 ± 2.3 64 ± 35 -5.2
2.3.13.02. Phosducin/Transducin beta-gamma complex, conformation 3 1b9x Rattus norvegicus Eukaryo. plasma 3 0 1.0 ± 1.6 49 ± 12 -3.9
2.3.08.02. Cytosolic phospholipase A2 delta, structure 2 5iz5 Homo sapiens Vesicle 1 0 1.0 ± 0.0 77 ± 0 -4.1
2.3.16.06. ADP-ribosylation factor-like protein 8A 2h18 Homo sapiens Endosome 1 0 1.2 ± 3.6 58 ± 28 -2.6
2.3.14.01. Retinaldehyde-binding protein 1, closed state 3hx3 Homo sapiens Eukaryo. plasma 1 0 1.2 ± 2.9 77 ± 32 -4.8
2.3.11.01. Ferrochelatase, conformation 2 (with porphyrin bound) 4klr Homo sapiens Mitochon. inner 2 0 1.3 ± 0.0 90 ± 1 -8.4
2.3.29.01. Undecaprenyl pyrophosphate synthase 2d2r Helicobacter pylori Bact. Gram-neg inner 2 0 1.3 ± 0.9 78 ± 1 -4.5
2.3.25.02. Phospholipase A1 4hyq Streptomyces albidoflavus Secreted 1 0 1.4 ± 1.4 31 ± 7 -3.9
2.3.06.05. Copper inducible hydrolase YahD 3og9 Lactococcus lactis Bact. Gram-pos plas. 1 0 1.4 ± 1.1 33 ± 10 -4.0
2.3.12.01. Myotubularin-related protein 2, dimer 1m7r Homo sapiens Eukaryo. plasma 2 0 1.4 ± 0.3 89 ± 0 -6.4
2.3.19.01. Cytotoxin L 2vkh Clostridium sordellii Secreted 1 0 1.4 ± 2.0 51 ± 17 -4.5
2.3.23.01. Beta-Ketoacyl synthase/Acyl transferase 1tqy Streptomyces coelicolor Bact. Gram-pos plas. 2 0 1.4 ± 0.2 83 ± 1 -4.9
2.3.01.08. Endoglucanase H 2vi0 Clostridium thermocellum Bact. Gram-pos plas. 1 0 1.5 ± 1.3 36 ± 9 -3.8
2.3.16.06. ADP-ribosylation factor-like protein 5A 1z6y Homo sapiens Eukaryo. plasma 1 0 1.5 ± 1.9 66 ± 15 -4.0
2.3.06.12. Heroin esterase 1lzk Rhodococcus sp. Bact. Gram-pos plas. 1 0 1.5 ± 1.5 69 ± 9 -4.0
2.3.18.01. Choline O-acetyltransferase 2fy2 Homo sapiens Eukaryo. plasma 1 0 1.5 ± 2.2 87 ± 17 -5.2
2.3.14.01. Neurofibromin 2d4q Homo sapiens Eukaryo. plasma 1 0 1.6 ± 2.0 34 ± 19 -3.3
2.3.16.06. ADP-ribosylation factor-like protein 1 2x77 Leishmania major Eukaryo. plasma 1 0 1.6 ± 1.4 80 ± 5 -3.6
2.3.01.03. Alpha-amylase A 1wza Halothermothrix orenii Secreted 1 0 1.6 ± 0.4 80 ± 1 -6.7
2.3.18.01. Carnitine O-octanoyltransferase 1nm8 Homo sapiens Mitochon. inner 1 0 1.7 ± 3.0 67 ± 15 -5.3
2.3.16.07. Ras-related protein Rab-7a 1vg8 Rattus norvegicus Endosome 1 0 1.7 ± 0.5 74 ± 3 -5.3
2.3.21.01. Protein-tyrosine phosphatase, mitochondrial 1 3rgq Mus musculus Mitochon. inner 1 0 1.7 ± 0.7 54 ± 7 -4.9
2.3.06.01. Neuroligin-2 3bl8 Mus musculus Eukaryo. plasma 1 0 1.7 ± 1.6 32 ± 5 -4.1
2.3.06.05. Carboxylesterase 2 1auo Pseudomonas fluorescens Bact. Gram-neg inner 1 0 1.7 ± 3.0 33 ± 21 -3.4
2.3.06.16. Lipase lip1 4opm Acinetobacter baumannii Secreted 1 0 1.8 ± 1.0 41 ± 3 -4.4
2.3.06.01. Acetylcholinesterase 1ea5 Torpedo californica Eukaryo. plasma 1 0 1.8 ± 1.1 34 ± 5 -4.7
2.3.06.02. MPT51/MPB51 antigen 1r88 Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 1.8 ± 1.0 28 ± 26 -3.9
2.3.06.01. Neuroligin-1, complex with human neurexin-1-alpha 3b3q Mus musculus Eukaryo. plasma 2 0 1.8 ± 1.0 81 ± 1 -3.6
2.3.06.01. Bile-salt activated lipase, structure 1 1f6w Homo sapiens Secreted 1 0 1.8 ± 0.5 81 ± 10 -5.1
2.3.01.09. Arabinogalactan endo-1,4-beta-galactosidase 1hjq Humicola insolens (Soft-rot fungus) Secreted 1 0 1.8 ± 1.4 86 ± 7 -3.7
2.3.05.03. D-amino-acid oxidase 1ve9 Sus scrofa Peroxisome 2 0 1.9 ± 2.5 88 ± 4 -4.8
2.3.06.17. Group XV phospholipase A2 4x90 Homo sapiens Lysosome 1 0 1.9 ± 0.5 56 ± 1 -7.3
2.3.06.06. Triacylglycerol lipase 1lgy Rhizopus niveus Secreted 1 0 1.9 ± 1.8 33 ± 16 -4.8
2.3.16.07. Ras-related protein Rab-9A 1wms Homo sapiens Eukaryo. plasma 1 0 1.9 ± 0.8 48 ± 7 -5.0
2.3.01.04. Hyaluronidase 1fcq Apis mellifera Secreted 1 0 1.9 ± 2.7 36 ± 13 -3.7
2.4.10.01. Synapsin I 1auv Bos taurus Vesicle 1 0 1.9 ± 1.1 86 ± 11 -5.2
2.3.06.01. Neuroligin-4, X-linked, complex with neurexin 1-beta 2xb6 Homo sapiens Eukaryo. plasma 2 0 1.9 ± 3.0 84 ± 11 -3.3
2.3.06.19. Lipase A 1isp Bacillus subtilis Secreted 1 0 1.9 ± 0.8 59 ± 12 -5.2
2.3.25.02. GDSL-like lipase 3p94 Parabacteroides distasonis Secreted 1 0 2.0 ± 2.0 68 ± 6 -4.2
2.3.19.01. Toxin B 2bvl Clostridium difficile Secreted 1 0 2.0 ± 1.1 24 ± 14 -4.2
2.3.17.02. Folic acid synthesis protein FOL1 2bmb Saccharomyces cerevisiae Mitochon. inner 1 0 2.0 ± 0.6 31 ± 2 -5.8
2.3.14.01. Retinaldehyde-binding protein 1, closed state, more complete structure 3hy5 Homo sapiens Eukaryo. plasma 1 0 2.0 ± 3.9 55 ± 17 -4.5
2.3.06.01. Acetylcholinesterase 4qww Bungarus fasciatus Secreted 1 0 2.0 ± 1.5 36 ± 32 -3.0
2.3.18.01. Choline O-acetyltransferase, different conformation 1t1u Rattus norvegicus Eukaryo. plasma 1 0 2.1 ± 1.7 73 ± 15 -6.8
2.3.31.01. Sorbose-specific phosphotransferase enzyme IIB component 1nrz Klebsiella pneumoniae Bact. Gram-neg inner 1 0 2.1 ± 0.7 83 ± 3 -4.5
2.3.06.12. Lipase/esterase 3bjr Lactobacillus plantarum Secreted 1 0 2.1 ± 0.2 72 ± 5 -7.0
2.3.19.02. Histo-blood group ABO system transferase 2rj6 Homo sapiens Golgi 1 0 2.1 ± 1.3 77 ± 3 -7.1
2.3.13.03. Thiol-disulfide interchange protein DsbA 1u3a Escherichia coli Bact. Gram-neg inner 1 0 2.2 ± 1.4 86 ± 8 -4.2
2.3.02.01. Phospholipase C-beta isoform 2 2zkm Homo sapiens Eukaryo. plasma 1 0 2.2 ± 2.9 38 ± 12 -3.6
2.3.13.02. Phosducin/Transducin beta-gamma complex, conformation 2 2trc Rattus norvegicus Eukaryo. plasma 3 0 2.2 ± 1.0 62 ± 10 -4.9
2.3.06.05. Carboxylesterase 2h1i Bacillus cereus Bact. Gram-pos plas. 1 0 2.3 ± 1.8 32 ± 31 -3.6
2.3.13.02. Phosducin/Transducin beta-gamma complex, conformation 1 1a0r Bos taurus Eukaryo. plasma 3 0 2.3 ± 1.0 50 ± 4 -7.4
2.3.05.02. Adrenodoxin reductase of mitochondrial p450 systems, complex with adrenodoxin 1e6e Bos taurus Mitochon. inner 2 0 2.3 ± 1.0 11 ± 2 -4.1
2.3.01.01. Glucosylceramidase 2vt0 Pan troglodytes Lysosome 1 0 2.3 ± 1.0 86 ± 5 -7.3
2.3.05.02. Sulfide-quinone reductase 3h28 Aquifex aeolicus Bact. Gram-neg inner 3 0 2.4 ± 0.1 90 ± 0 -19.4
2.3.01.02. Dhurrinase 1v02 Sorghum bicolor Secreted 2 0 2.4 ± 0.5 89 ± 9 -5.1
2.3.06.12. Esterase LipW 3qh4 Mycobacterium marinum Bact. Gram-pos plas. 1 0 2.4 ± 1.2 76 ± 32 -5.0
2.3.08.01. Patatin-like protein, PlpD 5fqu Pseudomonas aeruginosa Secreted 2 0 2.4 ± 0.6 90 ± 3 -5.6
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 1 2w61 Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.4 ± 2.3 60 ± 7 -5.4
2.3.16.02. Translocation ATPase SecA 1tf5 Bacillus subtilis Bact. Gram-pos plas. 1 0 2.5 ± 1.1 64 ± 5 -7.0
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 3 5fih Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.5 ± 0.6 89 ± 1 -5.3
2.3.06.15. Polyneuridine-aldehyde esterase 2wfm Rauvolfia serpentina (Serpentwood) Endoplasm. reticulum 1 0 2.5 ± 1.7 88 ± 3 -4.6
2.3.16.08. Interferon-inducible GTPase 1 1tpz Mus musculus Endoplasm. reticulum 1 0 2.5 ± 2.0 37 ± 7 -5.0
2.3.24.01. Phosphatase YidA 1rkq Escherichia coli Undefined 1 0 2.5 ± 1.3 79 ± 9 -4.1
2.3.17.02. Dihydropteroate synthase 1tx2 Bacillus anthracis Bact. Gram-pos plas. 2 0 2.5 ± 0.3 90 ± 2 -7.7
2.3.06.12. Gibberellin receptor GID1A 2zsh Arabidopsis thaliana Nuclear inner 1 0 2.6 ± 1.2 89 ± 6 -5.0
2.3.16.01. Shikimate kinase 1e6c Erwinia chrysanthemi Bact. Gram-neg inner 2 0 2.6 ± 1.8 90 ± 12 -5.8
2.3.16.07. GTP-binding protein Rheb 1xtq Homo sapiens Eukaryo. plasma 1 0 2.6 ± 0.6 76 ± 20 -5.1
2.3.06.01. Acetylcholinesterase 5x61 Anopheles gambiae (African malaria mosquito) Eukaryo. plasma 1 0 2.6 ± 1.5 37 ± 4 -4.0
2.3.01.05. 1,3-beta-glucanosyltransferase, structure 2 2w62 Saccharomyces cerevisiae Eukaryo. plasma 1 0 2.7 ± 0.5 90 ± 1 -6.1
2.3.06.06. Triacylglycerol lipase, closed (inactive) state 3tgl Rhizomucor miehei Secreted 1 0 2.7 ± 1.1 39 ± 7 -5.8
2.3.09.01. Cytidylyltransferase 3hl4 Rattus norvegicus Eukaryo. plasma 2 0 2.7 ± 4.0 74 ± 8 -3.2
2.3.01.07. Chitinase A 1nh6 Serratia marcescens Secreted 1 0 2.7 ± 1.3 80 ± 5 -6.1
2.3.06.06. Mono- and diacylglycerol lipase 5ch8 Penicillium cyclopium Secreted 1 0 2.7 ± 0.3 9 ± 7 -4.2
2.3.11.01. Ferrochelatase, conformation 1 1hrk Homo sapiens Mitochon. inner 2 0 2.7 ± 0.1 90 ± 0 -9.9
2.3.28.01. Aldo-keto reductase family 1 member C1 1qwk Caenorhabditis elegans Undefined 1 0 2.8 ± 1.0 66 ± 3 -6.3
2.3.06.12. Carboxylesterase (EstA) 1jji Archaeoglobus fulgidus Archaebac. 1 0 2.8 ± 1.0 56 ± 22 -4.8
2.3.28.01. Aldo-keto reductase family 1 member C21 3fjn Mus musculus Undefined 1 0 2.8 ± 1.0 56 ± 3 -5.2
2.3.06.02. Antigen 85a 1sfr Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 2.8 ± 0.8 27 ± 9 -7.5
2.3.06.17. Phosphatidylcholine-sterol acyltransferase, structure 3 5bv7 Homo sapiens Secreted 1 0 2.8 ± 3.1 76 ± 15 -6.1
2.3.16.06. ADP-ribosylation factor 1 (ARF1) 2k5u Saccharomyces cerevisiae Golgi 1 0 2.9 ± 1.6 24 ± 18 -5.5
2.3.14.01. Yeast Sec14 Homolog Sfh1 (YKL091C) 3b7n Saccharomyces cerevisiae Nuclear outer 1 0 2.9 ± 1.5 65 ± 18 -5.8
2.3.06.12. Carboxylesterase 3wj2 Thermoplasma acidophilum Secreted 1 0 2.9 ± 1.9 81 ± 9 -5.1
2.3.06.07. Tentative lipase 2zyr Archaeoglobus fulgidus Secreted 1 0 3.0 ± 1.0 57 ± 8 -7.5
2.3.30.01. Aspartate carbamoyltransferase 5ilq Plasmodium falciparum Chloroplast outer 3 0 3.0 ± 0.4 88 ± 1 -7.2
2.3.18.01. Carnitine O-acetyltransferase 1ndb Mus musculus Mitochon. inner 1 0 3.0 ± 0.9 85 ± 6 -7.6
2.3.18.01. Carnitine O-acetyltransferase, complex with substrate 2h3u Mus musculus Mitochon. inner 1 0 3.0 ± 1.0 87 ± 3 -5.9
2.3.02.03. Phospholipase D 3rlh Loxosceles intermedia Secreted 1 0 3.0 ± 0.7 81 ± 6 -6.2
2.3.13.06. Chloride intracellular channel protein 1 1rk4 Homo sapiens Nuclear outer 1 0 3.0 ± 1.0 40 ± 5 -5.5
2.3.13.04. Glutathione peroxidase-like protein 2vup Trypanosoma brucei Undefined 1 0 3.0 ± 1.7 84 ± 7 -4.1
2.3.06.05. Esterase 5dwd Pelagibacterium halotolerans Secreted 1 0 3.1 ± 2.1 66 ± 20 -4.7
2.3.13.01. Glutathione transferase GST1-4 3g7j Anopheles dirus Undefined 2 0 3.1 ± 0.3 88 ± 1 -7.6
2.3.12.01. Myotubularin-related protein 2, monomer 1zvr Homo sapiens Endosome 1 0 3.1 ± 0.4 89 ± 8 -5.0
2.3.10.03. LPS heptosyltransferase II, WaaF 1psw Escherichia coli Bact. Gram-neg inner 1 0 3.1 ± 1.1 58 ± 8 -5.6
2.3.22.01. Uncharacterized protein 1rtt Pseudomonas aeruginosa Undefined 1 0 3.1 ± 2.5 70 ± 22 -4.1
2.3.06.01. Butyryl cholinesterase 1p0i Homo sapiens Eukaryo. plasma 1 0 3.1 ± 0.8 43 ± 10 -6.4
2.3.06.12. Sulfolobus shibatae 3wj1 Sulfolobus shibatae Secreted 1 0 3.1 ± 0.7 52 ± 6 -6.3
2.3.06.18. Tle1 effector of type VI lipase 4o5p Pseudomonas aeruginosa Secreted 1 0 3.1 ± 2.5 85 ± 8 -5.8
2.3.06.01. Acetylcholinesterase 4ey4 Homo sapiens Eukaryo. plasma 1 0 3.2 ± 0.5 33 ± 2 -8.4
2.3.02.01. Phospholipase C-beta isoform 3, complex with Galpha Q, structure 2 4qj3 Homo sapiens Eukaryo. plasma 2 0 3.2 ± 1.7 63 ± 10 -6.2
2.3.19.01. Toxin A 4r04 Clostridium difficile Secreted 1 0 3.2 ± 2.4 74 ± 2 -6.7
2.3.09.01. Cytidylyltransferase, first membrane-anchoring helix 1peh Rattus norvegicus Eukaryo. plasma 1 0 3.2 ± 0.6 90 ± 2 -5.0
2.3.06.06. Lipase 4l3w Rhizopus chinensis Secreted 1 0 3.2 ± 0.7 31 ± 2 -6.5
2.3.19.01. Alpha-toxin 2vk9 Clostridium novyi Secreted 1 0 3.2 ± 1.0 80 ± 2 -5.2
2.3.16.07. Ras-related C3 botulinum toxin substrate 1 2p2l Homo sapiens Eukaryo. plasma 1 0 3.2 ± 0.8 58 ± 2 -5.2
2.3.06.03. Gastric lipase, closed state 1hlg Homo sapiens Secreted 1 0 3.2 ± 1.4 6 ± 12 -5.6
2.3.15.02. FAD synthase 2wsi Saccharomyces cerevisiae Mitochon. inner 1 0 3.3 ± 1.7 65 ± 17 -4.0
2.3.16.06. ADP-ribosylation factor-like protein 3 1fzq Mus musculus Golgi 1 0 3.3 ± 1.1 73 ± 9 -5.8
2.3.06.04. Acyl transferase LuxD 1tht Vibrio harveyi Bact. Gram-neg inner 1 0 3.3 ± 1.3 85 ± 4 -6.1
2.3.16.09. GTP-binding protein YjiA 1nij Escherichia coli Bact. Gram-neg inner 1 0 3.4 ± 0.1 41 ± 1 -6.7
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 1 2gek Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 3.4 ± 2.6 85 ± 5 -5.7
2.3.13.04. Glutathione peroxidase 8 3kij Homo sapiens Endoplasm. reticulum 1 0 3.4 ± 2.7 56 ± 16 -6.1
2.3.06.08. Phospholipase A1 4qnn Vespa basalis Secreted 1 0 3.5 ± 0.5 64 ± 2 -11.1
2.3.06.07. Lipase L1, isoform 1 1ji3 Bacillus stearothermophilus Secreted 1 0 3.5 ± 1.7 22 ± 10 -8.0
2.3.06.08. Pancreatic lipase 1bu8 Rattus norvegicus Secreted 1 0 3.5 ± 1.3 87 ± 10 -6.1
2.3.05.05. Secretory pathway GDP dissociation inhibitor 2bcg Saccharomyces cerevisiae Endoplasm. reticulum 2 0 3.5 ± 1.0 70 ± 6 -8.5
2.3.06.05. Carboxylesterase 3cn9 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 3.5 ± 2.1 11 ± 32 -4.1
2.3.06.04. Palmitoyl-protein thioesterase 1 3gro Homo sapiens Lysosome 1 0 3.6 ± 0.1 55 ± 3 -6.8
2.3.18.01. Choline O-acetyltransferase 1q6x Rattus norvegicus Eukaryo. plasma 1 0 3.6 ± 0.6 75 ± 6 -8.5
2.3.14.01. SEC14-like protein 2 (supernatant factor protein) 1o6u Homo sapiens Eukaryo. plasma 1 0 3.6 ± 1.4 62 ± 14 -4.9
2.3.19.03. Galactofuranosyl transferase GlfT2 4fix Mycobacterium tuberculosis Bact. Gram-pos plas. 4 0 3.6 ± 0.0 90 ± 0 -24.8
2.3.24.02. Phosphoglycolate phosphatase 1l6r Thermoplasma acidophilum Undefined 1 0 3.6 ± 0.5 86 ± 3 -7.5
2.3.24.02. Predicted hydrolase 3mpo Lactobacillus brevis Undefined 1 0 3.6 ± 0.0 83 ± 7 -5.7
2.3.22.02. NrdI protein 2x2o Bacillus cereus Undefined 1 0 3.6 ± 0.5 77 ± 4 -4.6
2.3.06.17. Phosphatidylcholine-sterol acyltransferase, structure 2 4xwg Homo sapiens Secreted 1 0 3.7 ± 0.7 37 ± 4 -6.1
2.3.06.06. Lipase B, open state 1lbs Candida antarctica Secreted 1 0 3.7 ± 1.0 76 ± 6 -12.7
2.3.06.02. Antigen 85b 1f0n Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 3.7 ± 0.9 33 ± 7 -7.4
2.3.06.01. Acetylcholinesterase 1n5m Mus musculus Eukaryo. plasma 1 0 3.7 ± 1.3 28 ± 6 -6.1
2.3.06.07. Lipase 4gw3 Proteus mirabilis Secreted 1 0 3.7 ± 0.9 43 ± 7 -5.1
2.3.02.04. Phosphatidylinositol-specific phospholipase C1 3h4x Streptomyces antibioticus Bact. Gram-pos plas. 1 0 3.7 ± 0.4 63 ± 2 -7.3
2.3.10.07. Lipopolysaccharide biosynthesis protein RfaG 2iw1 Escherichia coli Bact. Gram-neg inner 1 0 3.7 ± 3.1 85 ± 8 -6.0
2.3.06.04. Palmitoyl protein thioesterase 2 1pja Homo sapiens Lysosome 1 0 3.7 ± 1.6 60 ± 15 -4.6
2.3.06.07. Lipase 1qge Pseudomonas glumae Secreted 1 0 3.7 ± 0.9 24 ± 3 -7.7
2.3.06.08. Pancreatic lipase 1hpl Equus caballus Secreted 1 0 3.8 ± 0.3 80 ± 5 -8.1
2.3.06.01. Bile-salt activated lipase, conformation 2 1akn Bos taurus Secreted 1 0 3.8 ± 1.5 77 ± 15 -6.7
2.3.01.07. Chitinase B 1h0i Serratia marcescens Secreted 1 0 3.8 ± 1.4 70 ± 12 -5.2
2.3.06.06. Triacylglycerol lipase 3g7n Penicillium expansum Secreted 1 0 3.8 ± 1.1 81 ± 14 -9.0
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1t6m Bacillus thuringiensis Secreted 1 0 3.8 ± 1.4 89 ± 13 -4.9
2.3.01.02. Beta-glycosidase 1vff Pyrococcus horikoshii Archaebac. 1 0 3.9 ± 1.6 39 ± 10 -9.7
2.3.18.01. Carnitine O-palmitoyltransferase 1, liver isoform, N-terminal domain 2le3 Homo sapiens Mitochon. outer 1 0 3.9 ± 3.7 80 ± 3 -9.3
2.3.27.01. Dihydrofolate reductase 3nzb Pneumocystis carinii Undefined 1 0 3.9 ± 1.9 72 ± 10 -5.9
2.3.08.01. Patatin 1oxw Solanum cardiophyllum Secreted 1 0 3.9 ± 2.0 28 ± 11 -6.5
2.3.16.01. Shikimate kinase 1via Campylobacter jejuni Bact. Gram-neg inner 2 0 3.9 ± 1.4 89 ± 11 -5.0
2.3.25.02. Lipase 5mal Streptomyces rimosus Secreted 1 0 3.9 ± 0.8 64 ± 20 -6.3
2.3.18.01. Carnitine O-palmitoyltransferase 2 2h4t Rattus norvegicus Mitochon. inner 1 0 4.0 ± 1.2 67 ± 10 -9.4
2.3.06.07. Lipase L1 1ku0 Bacillus stearothermophilus Secreted 1 0 4.0 ± 0.6 23 ± 9 -8.9
2.3.16.04. Dynamin-like protein 2j69 Nostoc punctiforme Bact. Gram-neg inner 1 0 4.0 ± 7.0 15 ± 10 -5.5
2.3.06.05. Thermostable Esterase 3doh Thermotoga maritima Bact. Gram-neg inner 1 0 4.0 ± 2.0 84 ± 13 -4.4
2.3.05.04. Reticulon-4-interacting protein 1 2vn8 Homo sapiens Mitochon. inner 1 0 4.0 ± 0.0 82 ± 0 -10.2
2.3.22.02. NrdI protein 2xod Bacillus anthracis Undefined 1 0 4.1 ± 0.4 72 ± 3 -4.8
2.3.02.01. Phospholipase C-delta isoform 1 1djx Rattus norvegicus Eukaryo. plasma 1 0 4.1 ± 0.9 68 ± 5 -7.2
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 2 4nc9 Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 4.1 ± 1.1 69 ± 7 -7.9
2.3.06.19. PHB depolymerase PhaZ7, structure 1 2x5x Pseudomonas lemoignei Secreted 1 0 4.1 ± 3.0 54 ± 41 -5.6
2.3.33.01. Endo-beta-N-acetylglucosaminidase 2vtf Arthrobacter protophormiae Secreted 1 0 4.1 ± 0.7 52 ± 2 -6.5
2.3.04.01. Tyrosine-protein phosphatase CpsB 2wje Streptococcus pneumoniae Bact. Gram-pos plas. 1 0 4.2 ± 2.8 76 ± 26 -4.6
2.3.06.02. Antigen 85c, conformation 1 1va5 Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 4.2 ± 0.2 34 ± 3 -8.2
2.3.01.01. Glucosylceramidase 1ogs Homo sapiens Lysosome 1 0 4.2 ± 1.1 89 ± 4 -9.0
2.3.24.01. Phosphonoacetaldehyde hydrolase 1rdf Bacillus cereus Undefined 1 0 4.3 ± 0.9 68 ± 4 -5.1
2.3.06.11. Monoglyceride lipase 4zwn Saccharomyces cerevisiae Endoplasm. reticulum 1 0 4.3 ± 1.7 11 ± 17 -7.5
2.3.02.02. Phosphatidylinositol-specific phospholipase C 4f2t Staphylococcus aureus Secreted 1 0 4.3 ± 0.5 65 ± 5 -7.8
2.3.16.07. Ras-related protein Rab-5C 4kyi Homo sapiens Eukaryo. plasma 1 0 4.3 ± 1.4 73 ± 1 -6.0
2.3.06.17. Phosphatidylcholine-sterol acyltransferase, structure 1 4x96 Homo sapiens Secreted 1 0 4.3 ± 1.1 67 ± 4 -7.9
2.3.15.01. Electron transfer flavoprotein 1efp Paracoccus denitrificans Bact. Gram-neg inner 2 0 4.3 ± 1.1 90 ± 13 -4.8
2.3.12.01. Myotubularin-related protein 8, dimer 4y7i Homo sapiens Nuclear outer 2 0 4.3 ± 0.4 89 ± 5 -10.7
2.3.14.01. Alpha-tocopherol transfer protein, closed state with ligand 1r5l Homo sapiens Golgi 1 0 4.3 ± 1.0 77 ± 9 -11.8
2.3.06.06. Lipase A, closed state 3guu Candida antarctica Secreted 1 0 4.4 ± 1.0 80 ± 2 -10.9
2.3.25.02. Lipolytic protein 3rjt Alicyclobacillus acidocaldarius Secreted 1 0 4.4 ± 4.4 89 ± 1 -6.3
2.3.32.01. UDP-N-acetylmuramate--L-alanine ligase 1p31 Haemophilus influenzae Bact. Gram-neg inner 1 0 4.4 ± 1.8 29 ± 14 -4.6
2.2.29.01. Multivesicular body subunit 12B 3tow Homo sapiens Endosome 1 0 4.5 ± 2.3 33 ± 22 -5.8
2.3.16.04. EH domain-containing protein 2 2qpt Mus musculus Endosome 2 0 4.5 ± 2.1 20 ± 14 -7.8
2.3.10.07. Lipopolysaccharide biosynthesis protein RfaG, 103-131 2n58 Escherichia coli Bact. Gram-neg inner 1 0 4.5 ± 1.1 64 ± 7 -6.3
2.3.05.03. Glycerol-3-phosphate dehydrogenase (GlpD) 2qcu Escherichia coli Bact. Gram-neg inner 1 0 4.5 ± 1.5 74 ± 11 -8.4
2.3.06.18. Protein lpg2422 4m0m Legionella pneumophila Undefined 1 0 4.6 ± 2.9 76 ± 6 -6.9
2.3.06.07. Lipase 46 kDa form 2hih Staphylococcus hyicus Secreted 1 0 4.6 ± 0.3 83 ± 1 -16.0
2.3.13.05. Putative peroxiredoxin Rv2238c/MT2298 1xvw Mycobacterium tuberculosis Undefined 1 0 4.6 ± 1.0 20 ± 5 -7.0
2.3.15.01. Electron transfer flavoprotein 1efv Homo sapiens Mitochon. inner 2 0 4.6 ± 1.3 79 ± 12 -4.6
2.3.16.06. ADP-ribosylation factor 1 (ARF1), different conformation 2ksq Saccharomyces cerevisiae Golgi 1 0 4.7 ± 0.1 62 ± 0 -10.4
2.3.13.01. Microsomal prostaglandin E synthase 2 1z9h Macaca fascicularis Golgi 2 0 4.8 ± 0.5 90 ± 4 -15.7
2.3.05.02. Rotenone-insensitive NADH-ubiquinone oxidoreductase, NDI1 4g6h Saccharomyces cerevisiae Mitochon. inner 2 0 4.8 ± 0.0 88 ± 1 -13.9
2.3.13.01. Stringent starvation protein A 3mdk Pseudomonas putida Undefined 2 0 4.8 ± 0.1 89 ± 0 -5.5
2.3.01.02. Beta-glucosidase 6 3gnr Oryza sativa (Rice) Secreted 1 0 4.8 ± 0.2 80 ± 1 -12.4
2.3.12.01. Myotubularin-related protein 1 5c16 Homo sapiens Eukaryo. plasma 1 0 4.8 ± 0.7 70 ± 16 -5.3
2.3.06.06. Lipase 2 1gz7 Candida rugosa Secreted 1 0 4.8 ± 1.3 87 ± 10 -8.5
2.3.10.01. Peptidoglycan biosynthesis glycosyltransferase MurG, conformation 1 1nlm Escherichia coli Bact. Gram-neg inner 1 0 4.8 ± 1.1 50 ± 7 -7.5
2.3.06.08. Pancreatic lipase-related protein 2 1w52 Equus caballus Secreted 1 0 4.8 ± 0.2 83 ± 0 -12.7
2.3.06.07. Thermostable lipase 2dsn Geobacillus zalihae Secreted 1 0 4.9 ± 0.9 32 ± 3 -7.7
2.3.06.09. Cutinase 4oyy Humicola insolens (Soft-rot fungus) Secreted 1 0 4.9 ± 1.4 46 ± 6 -10.0
2.3.06.06. Lipase 1, closed (inactive) state 1trh Candida rugosa Secreted 1 0 4.9 ± 1.3 85 ± 7 -7.4
2.3.09.01. Cytidylyltransferase, second membrane-anchoring helix 1pei Rattus norvegicus Eukaryo. plasma 1 0 4.9 ± 1.0 83 ± 11 -8.2
2.3.06.09. Cutinase-like protein 2czq Cryptococcus sp. Secreted 1 0 4.9 ± 1.3 54 ± 16 -9.0
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1gym Bacillus cereus Secreted 1 0 4.9 ± 1.0 67 ± 11 -7.2
2.3.16.03. Transducin 1got Bos taurus Eukaryo. plasma 3 0 4.9 ± 1.2 61 ± 8 -7.0
2.3.06.01. Bile-salt activated lipase, structure 2 1jmy Homo sapiens Secreted 1 0 5.0 ± 1.4 85 ± 9 -5.3
2.3.06.10. Lipase 1jfr Streptomyces exfoliatus Secreted 1 0 5.0 ± 1.3 60 ± 10 -6.4
2.3.003.01. Gamma-ketol reductase 5a3v Arabidopsis thaliana Chloroplast inner 1 0 5.0 ± 0.6 89 ± 4 -8.9
2.3.06.07. Organic solvent tolerant lipase 42 4fkb Bacillus sp. Secreted 1 0 5.0 ± 0.7 26 ± 3 -6.9
2.3.10.03. Heptosyltransferase WaaC 2h1h Escherichia coli Bact. Gram-neg inner 1 0 5.0 ± 1.1 67 ± 5 -9.1
2.3.06.07. Lipase L1, isoform 2 4fmp Bacillus stearothermophilus Secreted 1 0 5.0 ± 1.6 25 ± 12 -8.9
2.3.06.06. Triacylglycerol lipase, closed (inactive) state 1dt5 Humicola lanuginosa Secreted 1 0 5.1 ± 0.9 79 ± 13 -5.9
2.3.20.01. Hydrophilic domain of respiratory complex I 3i9v Thermus thermophilus Bact. Gram-neg inner 8 0 5.1 ± 1.4 34 ± 10 -11.6
2.3.06.02. Antigen 85c, conformation 3 1dqy Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 5.1 ± 1.2 17 ± 3 -6.1
2.3.06.14. Esterase LipA 3h2g Xanthomonas oryzae Secreted 1 0 5.1 ± 1.7 87 ± 8 -4.9
2.3.01.10. Galactocerebrosidase 3zr5 Mus musculus Lysosome 1 0 5.2 ± 0.6 87 ± 1 -15.3
2.3.02.01. Phospholipase C-beta isoform 3, complex with Galpha Q, structure 3 4gnk Homo sapiens Eukaryo. plasma 2 0 5.2 ± 1.4 56 ± 3 -7.8
2.3.10.02. Beta-1,2-glucuronosyltrnansferase GumK 2q6v Xanthomonas campestris Bact. Gram-neg inner 1 0 5.2 ± 1.0 61 ± 8 -9.5
2.3.06.07. Thermostable lipase 4fdm Bacillus sp. Secreted 1 0 5.2 ± 0.6 28 ± 2 -8.5
2.3.06.12. Gibberellin receptor GID1 3ebl Oryza sativa (Rice) Nuclear inner 1 0 5.2 ± 1.5 59 ± 14 -9.1
2.3.25.02. LAE5 5jd3 Uncultured bacterium Undefined 1 0 5.3 ± 5.3 75 ± 3 -7.4
2.3.11.01. Ferrochelatase, mitochondrial 1lbq Saccharomyces cerevisiae Mitochon. inner 2 0 5.3 ± 0.5 90 ± 3 -6.9
2.3.10.01. Peptidoglycan biosynthesis glycosyltransferase MurG, conformation 2 1f0k Escherichia coli Bact. Gram-neg inner 1 0 5.3 ± 1.2 55 ± 7 -8.6
2.3.06.04. Palmitoyl protein thioesterase 1 1eh5 Bos taurus Lysosome 1 0 5.3 ± 0.9 59 ± 6 -8.1
2.3.06.02. Antigen 85c, conformation 2 4qdu Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 5.3 ± 2.4 87 ± 16 -5.2
2.3.06.01. Bile-salt activated lipase, conformation 3 2bce Bos taurus Secreted 1 0 5.3 ± 0.8 74 ± 6 -7.0
2.3.07.01. Endoglucanase 1vho Thermotoga maritima Undefined 1 0 5.4 ± 0.2 89 ± 1 -7.0
2.3.06.10. Lipase 2fx5 Pseudomonas mendocina Secreted 1 0 5.5 ± 1.0 50 ± 5 -8.4
2.3.06.10. Platelet-activating factor acetylhydrolase 3d59 Homo sapiens Secreted 1 0 5.5 ± 1.2 87 ± 10 -13.6
2.3.06.01. Acetylcholinesterase 1qon Drosophila melanogaster Eukaryo. plasma 1 0 5.5 ± 1.6 4 ± 13 -5.0
2.3.08.02. Cytosolic phospholipase A2 delta, structure 1 5ixc Homo sapiens Vesicle 1 0 5.5 ± 2.0 85 ± 31 -4.4
2.3.06.07. Lipase 3auk Geobacillus sp. Secreted 1 0 5.6 ± 0.8 25 ± 2 -8.5
2.3.16.05. ATPase Get3, homodimer 3a36 Saccharomyces cerevisiae Endoplasm. reticulum 2 0 5.6 ± 3.0 66 ± 10 -6.6
2.3.10.06. Alpha-(1-2)-phosphatidylinositol mannosyltransferase, structure 3 4n9w Mycobacterium smegmatis Bact. Gram-pos plas. 1 0 5.6 ± 1.2 84 ± 3 -4.6
2.3.24.02. Hydrolase 3n1u Legionella pneumophila Undefined 4 0 5.6 ± 0.6 90 ± 1 -10.8
2.3.06.07. Triacylglycerol lipase 2w22 Geobacillus thermocatenulatus Secreted 1 0 5.6 ± 0.0 86 ± 0 -22.4
2.3.06.16. Putative epoxide hydrolase 5bov Klebsiella pneumoniae Secreted 1 0 5.7 ± 1.4 23 ± 10 -5.1
2.3.06.09. Cutinase 1 3dcn Colletotrichum gloeosporioides Secreted 1 0 5.7 ± 1.2 44 ± 8 -10.1
2.3.06.01. Bile-salt activated lipase, conformation 1 1aql Bos taurus Secreted 1 0 5.7 ± 1.1 78 ± 7 -9.6
2.3.06.06. Triacylglycerol lipase, closed state 2 5ap9 Humicola lanuginosa Secreted 1 0 5.7 ± 0.4 79 ± 5 -6.1
2.3.06.08. Pancreatic lipase 1gpl Cavia porcellus Secreted 1 0 5.8 ± 1.0 86 ± 9 -7.8
2.3.06.06. Lipase 3zpx Ustilago maydis Secreted 1 0 5.8 ± 0.8 88 ± 1 -14.0
2.3.06.12. Carboxylesterase 2hm7 Alicyclobacillus acidocaldarius Bact. Gram-pos plas. 1 0 5.8 ± 1.7 70 ± 5 -7.7
2.3.08.02. Cytosolic phospholipase A2, group IVA 1cjy Homo sapiens Vesicle 1 0 5.8 ± 1.0 70 ± 9 -9.9
2.3.06.01. Butyryl cholinesterase, dimer 5dyy Homo sapiens Secreted 2 0 5.9 ± 0.5 88 ± 2 -11.5
2.3.06.01. Neuroligin-1, complex with neurexin-1-beta 3biw Rattus norvegicus Eukaryo. plasma 2 0 5.9 ± 1.0 80 ± 3 -8.8
2.3.14.02. Uncharacterized protein 2q3l Shewanella loihica Bact. Gram-neg inner 1 0 6.0 ± 0.5 64 ± 4 -12.6
2.3.01.06. Glycosyl hydrolase PslG 5bxa Pseudomonas aeruginosa Secreted 1 0 6.0 ± 1.2 72 ± 9 -6.9
2.3.06.09. Mycobacterial lipase 3aja Mycobacterium smegmatis Secreted 1 0 6.0 ± 1.0 28 ± 10 -6.7
2.3.34.01. N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D 4qn9 Homo sapiens Eukaryo. plasma 2 0 6.0 ± 1.6 87 ± 11 -11.3
2.3.14.01. Alpha-tocopherol transfer protein, open state 3w68 Mus musculus Golgi 1 0 6.0 ± 0.6 70 ± 2 -13.8
2.3.26.01. Phosphate acyltransferase 1u7n Enterococcus faecalis Bact. Gram-pos plas. 2 0 6.1 ± 1.5 78 ± 13 -6.1
2.3.05.02. FAD-dependent pyridine nucleotide-disulfide oxidoreductase 4nwz Caldalkalibacillus thermarum Bact. Gram-pos plas. 2 0 6.2 ± 1.0 90 ± 2 -13.7
2.3.06.09. Cutinase 5ajh Fusarium oxysporum Secreted 1 0 6.2 ± 0.3 25 ± 9 -7.6
2.3.06.08. Pancreatic lipase-related protein 1 1rp1 Canis lupus familiaris Secreted 1 0 6.3 ± 1.0 79 ± 4 -7.5
2.3.06.06. Lipase 2ory Photbacterium lipolyticum Secreted 1 0 6.3 ± 1.1 62 ± 10 -12.0
2.3.05.03. L-amino acid deaminase 5hxw Proteus vulgaris Bact. Gram-neg inner 1 0 6.4 ± 2.1 86 ± 6 -9.0
2.3.06.01. Carboxylic ester hydrolase, closed state 4be4 Ophiostoma piceae Secreted 1 0 6.4 ± 2.3 61 ± 4 -5.7
2.3.16.05. ATPase Get3, complex with Get1 cytosolic domain 3sja Saccharomyces cerevisiae Endoplasm. reticulum 4 0 6.4 ± 1.6 89 ± 45 -8.1
2.3.06.06. Lipase 2 1thg Geotrichum candidum Secreted 1 0 6.4 ± 1.7 23 ± 14 -4.7
2.3.06.09. Lysin B from mycobacteriophage 3hc7 Mycobacterium phage D29 Bact. Gram-pos plas. 1 0 6.6 ± 2.0 50 ± 12 -7.0
2.3.05.05. RabGDI protein 3p1w Plasmodium falciparum Eukaryo. plasma 1 0 6.6 ± 1.4 47 ± 3 -6.8
2.3.18.02. Phthiocerol/phthiodiolone dimycocerosyl transferase 1q9j Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 6.7 ± 2.2 25 ± 6 -5.2
2.3.06.07. Lipase I.3, closed state 2z8x Pseudomonas sp. Secreted 1 0 6.8 ± 1.7 74 ± 6 -8.2
2.3.06.09. Cutinase 1 1oxm Fusarium solani Secreted 1 0 6.8 ± 1.1 36 ± 15 -9.1
2.3.06.06. Lipase 2 3o0d Yarrowia lipolytica Secreted 1 0 6.8 ± 2.4 79 ± 26 -9.4
2.3.10.01. Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 3s2u Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 6.8 ± 0.9 60 ± 2 -8.3
2.3.16.06. ADP-ribosylation factor-like protein 2, complex with human PDEdelta 1ksg Mus musculus Eukaryo. plasma 1 0 6.9 ± 1.7 77 ± 15 -5.7
2.3.10.04. Teichoic acid biosynthesis protein TagF 3l7l Staphylococcus epidermidis Bact. Gram-pos plas. 1 0 6.9 ± 2.0 35 ± 15 -10.8
2.3.06.16. Putative hydrolase RPA1511 4psu Rhodopseudomonas palustris Secreted 1 0 7.0 ± 1.2 47 ± 4 -13.0
2.3.13.04. Phospholipid hydroperoxide glutathione peroxidase 5l71 Mus musculus Mitochon. inner 1 0 7.1 ± 1.8 83 ± 14 -5.1
2.3.05.06. Endothelin-converting enzyme 2 2pxx Homo sapiens Golgi 1 0 7.1 ± 1.3 37 ± 8 -8.4
2.3.06.08. Pancreatic lipase-related protein 1 2ppl Homo sapiens Secreted 1 0 7.1 ± 0.9 79 ± 6 -10.2
2.3.17.01. Phospho-2-dehydro-3-deoxyheptonate aldolase 1of8 Saccharomyces cerevisiae Undefined 2 0 7.2 ± 0.4 80 ± 6 -9.3
2.3.05.01. Flavoprotein-ubiquinone oxydoreductase 2gmh Sus scrofa Mitochon. inner 1 0 7.2 ± 0.8 38 ± 4 -18.5
2.3.10.01. Glycosyltransferase GtfA 1pn3 Amycolatopsis orientalis (Nocardia orientalis) Undefined 1 0 7.2 ± 1.0 80 ± 5 -7.7
2.3.06.03. Gastric lipase, open (active) state 1k8q Canis lupus familiaris Secreted 1 0 7.2 ± 0.5 78 ± 6 -12.6
2.3.02.02. Phosphatidylinositol-specific phospholipase C 1aod Listeria monocytogenes Secreted 1 0 7.4 ± 1.0 79 ± 10 -9.2
2.3.02.01. Phospholipase C-beta isoform 3, complex with Galpha Q, structure 1 3ohm Homo sapiens Eukaryo. plasma 2 0 7.5 ± 2.0 39 ± 5 -6.9
2.3.05.02. Type II NADH:ubiquinone oxidoreductase 5jwa Plasmodium falciparum Mitochon. inner 2 0 7.6 ± 0.0 90 ± 0 -11.3
2.3.06.08. Pancreatic lipase, complex with colipase from Pig 1n8s Homo sapiens Secreted 2 0 7.6 ± 0.6 45 ± 4 -10.8
2.3.16.10. Tetraacyldisaccharide 4-kinase, complex with ADP/ATP 4ehy Aquifex aeolicus Bact. Gram-neg inner 1 0 7.9 ± 0.9 71 ± 4 -12.1
2.3.25.01. Putative platelet activating factor 2hsj Streptococcus pneumoniae Undefined 2 0 7.9 ± 0.7 89 ± 4 -8.5
2.3.01.06. Endoglycoceramidase II 2osx Rhodococcus sp. Secreted 1 0 7.9 ± 0.4 68 ± 1 -13.4
2.3.16.10. Tetraacyldisaccharide 4-kinase 4ehx Aquifex aeolicus Bact. Gram-neg inner 1 0 8.0 ± 1.1 69 ± 3 -13.9
2.3.14.01. Alpha-tocopherol transfer protein, open state 1oiz Homo sapiens Golgi 1 0 8.1 ± 1.0 64 ± 10 -17.6
2.3.06.06. Triacylglycerol lipase, open (active) state 1ein Humicola lanuginosa Secreted 1 0 8.1 ± 0.8 63 ± 4 -14.5
2.3.06.11. Monoglyceride lipase MGLL, open ligand-free conformation 3jw8 Homo sapiens Eukaryo. plasma 1 0 8.1 ± 1.3 11 ± 9 -11.3
2.3.02.03. Sphingomyelinase D 1 1xx1 Loxosceles laeta Secreted 1 0 8.1 ± 1.0 70 ± 8 -10.6
2.3.06.13. Protein Ndr1 2xmr Homo sapiens Eukaryo. plasma 1 0 8.2 ± 2.6 50 ± 10 -8.8
2.3.10.05. 3-Deoxy-D-manno-octulosonic-acid transferase, WaaA 2xci Aquifex aeolicus Bact. Gram-neg outer 1 0 8.3 ± 1.5 72 ± 1 -20.3
2.3.06.13. Protein NDRG2 2qmq Mus musculus Eukaryo. plasma 1 0 8.3 ± 2.2 43 ± 14 -9.6
2.3.06.06. Lipase B, circular permutation 3icv Candida antarctica Secreted 2 0 8.3 ± 0.8 83 ± 7 -11.3
2.3.06.07. Lipase, complex with foldase 2es4 Pseudomonas glumae Secreted 2 0 8.5 ± 0.0 65 ± 2 -7.2
2.3.06.01. Carboxylic ester hydrolase, open state 4be9 Ophiostoma piceae Secreted 1 0 8.7 ± 0.4 88 ± 2 -30.9
2.3.14.01. Phosphatidylinositol transfer protein sec14p 1aua Saccharomyces cerevisiae Golgi 1 0 8.8 ± 1.1 75 ± 10 -14.3
2.3.06.06. Triacylglycerol lipase, open (active) state 4tgl Rhizomucor miehei Secreted 1 0 8.8 ± 0.9 64 ± 11 -18.2
2.3.06.06. Lipase LipA 2qua Serratia marcescens Secreted 1 0 8.9 ± 0.2 59 ± 0 -37.5
2.3.06.07. Lipase 5lip Burkholderia cepacia Secreted 1 0 9.0 ± 1.0 46 ± 2 -30.6
2.3.06.07. Lipase I.3, open state 3a70 Pseudomonas sp. Secreted 1 0 9.1 ± 1.0 58 ± 1 -32.9
2.3.06.08. Pancreatic lipase, complex with colipase from Pig 1lpb Homo sapiens Secreted 2 0 9.2 ± 0.4 89 ± 2 -24.2
2.3.06.05. Acyl-protein thioesterase 1 1fj2 Homo sapiens Eukaryo. plasma 1 0 9.6 ± 2.0 64 ± 14 -4.7
2.3.06.07. Lipase 1cvl Chromobacterium viscosum Secreted 1 0 9.9 ± 1.0 53 ± 9 -8.7
2.3.14.01. Phosphatidylinositol transfer protein PDR16 4fmm Saccharomyces cerevisiae Endoplasm. reticulum 1 0 9.9 ± 2.6 78 ± 19 -13.9
2.3.06.06. Lipase 1, open (active) state 1lpp Candida rugosa Secreted 1 0 10.0 ± 0.4 83 ± 1 -28.0
2.3.06.08. Pancreatic lipase-related protein 2 2oxe Homo sapiens Secreted 1 0 10.2 ± 1.1 88 ± 8 -10.1
2.3.06.06. Type-B carboxylesterase/lipase 1cle Candida cylindracea Secreted 1 0 10.2 ± 0.0 83 ± 0 -24.7
2.3.05.02. Sulfide-quinone reductase 3sx6 Acidithiobacillus ferrooxidans Bact. Gram-neg inner 1 0 10.6 ± 0.6 70 ± 8 -7.3
2.3.06.01. Acetylcholinesterase, complex with fasciculin-2 4bdt Homo sapiens Eukaryo. plasma 2 0 10.7 ± 0.8 56 ± 3 -11.6
2.3.06.07. Lipase, open (active) state 1ex9 Pseudomonas aeruginosa Secreted 1 0 11.0 ± 1.0 52 ± 5 -30.0
2.3.06.09. Cutinase 1 3gbs Aspergillus oryzae Secreted 1 0 11.2 ± 0.5 55 ± 5 -12.6
2.3.06.08. Pancreatic lipase, complex with colipase from Pig 1lpa Homo sapiens Secreted 2 0 11.3 ± 0.1 82 ± 1 -24.5
2.3.06.08. Pancreatic lipase, complex with colipase 1eth Sus scrofa Secreted 2 0 13.6 ± 0.2 90 ± 3 -13.3