PDB ID or protein name

Peptides of nonregular structure superfamilies

3.4.01. Gramicidin S (1 family)
3.4.02. Lantibiotic peptides (class I bacteriocins) (6 families) 1.C.20 (TCDB)
3.4.03. Heat-stable enterotoxin (1 family)
3.4.04. Cyclic lipopeptide antibiotics (2 families)
3.4.05. Cyclosporin (1 family)
3.4.06. Conomarphin (1 family)
3.4.07. Designed nonregular peptides (2 families)
3.4.08. Neurotensin/neuromedin N (1 family) PF07421 (Pfam)
3.4.09. Catestatin (1 family) PF01271 (Pfam)
See list of these PDB codes

Peptides of nonregular structure (24 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
3.4.04.02. Surfactin 2npv Bacillus subtilis Secreted 1 0 11.3 ± 2.1 55 ± 13 -11.3
3.4.05.01. Cyclosporin 1cwa Tolypocladium inflatum Secreted 1 0 10.2 ± 2.5 82 ± 53 -7.2
3.4.04.01. Tsushimycin 1w3m Streptomyces pseudogriseolus Secreted 1 0 9.5 ± 2.1 54 ± 24 -8.6
3.4.04.01. Daptomycin, Ca-free 1xt7 Streptomyces roseosporus Secreted 1 0 9.3 ± 3.9 10 ± 45 -6.4
3.4.04.01. Daptomycin, Ca-bound 1t5n Streptomyces roseosporus Secreted 1 0 8.6 ± 2.0 21 ± 24 -9.0
3.4.01.01. Gramicidin S 1tk2 Bacillus brevis Secreted 1 0 8.5 ± 1.7 86 ± 21 -8.6
3.4.02.03. Nisin-Lipid II complex in DMSO solution 1wco Lactococcus lactis Secreted 1 0 8.1 ± 1.0 90 ± 5 -8.0
3.4.08.01. Neurotensin 2oyv Homo sapiens Secreted 1 0 7.3 ± 2.6 67 ± 17 -5.3
3.4.02.05. Lichenicidin VK21 A1 2ktn Bacillus licheniformis Secreted 1 0 7.0 ± 1.5 77 ± 13 -5.9
3.4.02.05. Lichenicidin VK21 A2 2kto Bacillus licheniformis Secreted 1 0 6.6 ± 4.2 75 ± 3 -6.9
3.4.02.02. Mersacidin, structure in DPC micelles 1mqy Bacillus sp. Secreted 1 0 5.3 ± 0.9 90 ± 12 -6.1
3.4.02.02. Mersacidin, structure of lipid II bound peptide in DPC micelles 1mqz Bacillus sp. Secreted 1 0 4.2 ± 2.8 83 ± 15 -4.2
3.4.07.01. Antimicrobial cationic cyclic hexapeptide 1qvl Designed proteins Undefined 1 0 4.2 ± 1.6 84 ± 15 -6.8
3.4.06.01. Conomarphin 2jqc Conus marmoreus Secreted 1 0 4.1 ± 1.1 89 ± 12 -7.4
3.4.02.04. Cinnamycin 2dde Streptoverticillium griseoverticillatum Secreted 1 0 3.6 ± 1.9 30 ± 24 -5.4
3.4.07.02. Compstatin 1a1p Designed proteins Undefined 1 0 3.4 ± 1.9 72 ± 18 -5.6
3.4.02.02. Mersacidin, crystal structure 1qow Bacillus sp. Secreted 3 0 3.2 ± 2.7 72 ± 31 -5.5
3.4.03.01. Heat-stable enterotoxin ST-IA/ST-P 1etn Escherichia coli Secreted 1 0 3.0 ± 3.7 33 ± 39 -2.1
3.4.02.01. Actagardine, structure in acetonitrile solution 1aj1 Actinoplanes liguriae Secreted 1 0 3.0 ± 1.1 90 ± 11 -5.7
3.4.02.06. Epilancin 15X 1w9n Staphylococcus epidermidis Secreted 1 0 2.9 ± 1.0 72 ± 7 -5.0
3.4.04.01. Daptomycin, Ca-free 1t5m Streptomyces roseosporus Secreted 1 0 2.3 ± 1.3 33 ± 6 -7.9
3.4.09.01. Granin 1n2y Bos taurus Secreted 1 0 1.9 ± 2.1 71 ± 16 -3.4
3.4.02.02. Mersacidin, structure in methanol solution 1mqx Bacillus sp. Secreted 1 0 1.9 ± 1.3 87 ± 15 -2.9
3.4.09.01. Granin 1lv4 Homo sapiens Secreted 1 0 1.8 ± 0.4 81 ± 3 -6.8