PDB ID or protein name

Peptides of nonregular structure superfamilies

3.4.001. Contryphan (1 family)
3.4.002. Lantibiotic peptides (6 families)
3.4.003. Heat-stable enterotoxin (1 family)
3.4.004. Lipopeptide antibiotics (3 families)
3.4.005. Cyclosporin (1 family)
3.4.006. Conomarphin (1 family)
3.4.007. Designed nonregular peptides (2 families)
3.4.008. GPCR ligands (4 families)
3.4.009. Catestatin (1 family) PF01271 (Pfam)
3.4.010. Methanobactins (1 family)
3.4.012. Cyclic peptide antibiotics (3 families)
3.4.013. Nonregular protein segments (1 family)
See list of these PDB codes

Peptides of nonregular structure (41 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
3.4.04.01. Daptomycin, Ca-free 1xt7 Streptomyces roseosporus Secreted 1 0 9.3 ± 3.9 10 ± 45 -6.4
3.4.04.01. Daptomycin, Ca-bound 1t5n Streptomyces roseosporus Secreted 1 0 8.6 ± 2.0 21 ± 24 -9.0
3.4.12.02. Thiostrepton, epimer form 2l2y Streptomyces azureus Secreted 1 0 2.7 ± 2.9 29 ± 9 -5.3
3.4.02.04. Cinnamycin 2dde Streptoverticillium griseoverticillatum Secreted 1 0 3.6 ± 1.9 30 ± 24 -5.4
3.4.03.01. Heat-stable enterotoxin ST-IA/ST-P 1etn Escherichia coli Secreted 1 0 3.0 ± 3.7 33 ± 39 -2.1
3.4.04.01. Daptomycin, Ca-free, different conformation 1t5m Streptomyces roseosporus Secreted 1 0 2.3 ± 1.3 33 ± 6 -7.9
3.4.12.01. Actinomycin X2 1qfi Streptomyces antibioticus Secreted 1 0 15.2 ± 2.3 35 ± 34 -14.1
3.4.08.02. Somatostatin 2mi1 Homo sapiens Secreted 1 0 5.6 ± 1.5 43 ± 15 -6.2
3.4.04.01. Tsushimycin 1w3m Streptomyces pseudogriseolus Secreted 1 0 9.5 ± 2.1 54 ± 24 -8.6
3.4.04.02. Surfactin 2npv Bacillus subtilis Secreted 1 0 11.3 ± 2.1 55 ± 13 -11.3
3.4.01.01. Contryphan-In 2m6d Conus inscriptus Secreted 1 0 8.2 ± 1.0 57 ± 15 -5.8
3.4.08.01. Neurotensin 2oyv Homo sapiens Secreted 1 0 7.3 ± 2.6 67 ± 17 -5.3
3.4.10.01. Methanobactin 2xjh Methylosinus trichosporium Secreted 1 0 0.7 ± 0.7 67 ± 7 -2.9
3.4.12.03. Bacitracin 4k7t Bacillus subtilis Secreted 1 0 9.0 ± 0.9 69 ± 8 -8.4
3.4.09.01. Granin, cyclic analogue 1n2y Bos taurus Secreted 1 0 1.9 ± 2.1 71 ± 16 -3.4
3.4.02.03. Bovicin HJ50 2m8v Streptococcus equinus Secreted 1 0 2.8 ± 1.0 71 ± 8 -4.0
3.4.02.06. Epilancin 15X 1w9n Staphylococcus epidermidis Secreted 1 0 2.9 ± 1.0 72 ± 7 -5.0
3.4.02.03. Lantibiotic 107891 2mh5 Microbispora sp. Bact. Gram-pos plas. 1 0 7.3 ± 3.0 72 ± 38 -4.0
3.4.07.02. Compstatin 1a1p Designed proteins Undefined 1 0 3.4 ± 1.9 72 ± 18 -5.6
3.4.02.02. Mersacidin, crystal structure 1qow Bacillus sp. Secreted 3 0 3.2 ± 2.7 72 ± 31 -5.5
3.4.02.05. Lichenicidin VK21 A2 2kto Bacillus licheniformis Secreted 1 0 6.6 ± 4.2 75 ± 3 -6.9
3.4.12.01. Actinomycin Z3 1a7z Streptomyces antibioticus Secreted 1 0 10.0 ± 1.3 76 ± 24 -9.6
3.4.02.05. Lichenicidin VK21 A1 2ktn Bacillus licheniformis Secreted 1 0 7.0 ± 1.5 77 ± 13 -5.9
3.4.07.01. VG16KRKP peptide 2mwl Designed proteins Undefined 1 0 4.4 ± 1.3 79 ± 12 -3.6
3.4.09.01. Granin 1lv4 Homo sapiens Secreted 1 0 1.8 ± 0.4 81 ± 3 -6.8
3.4.13.01. T-cell-specific surface glycoprotein CD28, intracellular loop 2nae Mus musculus Eukaryo. plasma 1 0 0.9 ± 10.0 81 ± 3 -6.4
3.4.05.01. Cyclosporin 1cwa Tolypocladium inflatum Secreted 1 0 10.2 ± 2.5 82 ± 53 -7.2
3.4.02.02. Mersacidin, structure of lipid II bound peptide in DPC micelles 1mqz Bacillus sp. Secreted 1 0 4.2 ± 2.8 83 ± 15 -4.2
3.4.07.01. Antimicrobial cationic cyclic hexapeptide 1qvl Designed proteins Undefined 1 0 4.2 ± 1.6 84 ± 15 -6.8
3.4.08.04. Met-enkephalin 1plw Homo sapiens Secreted 1 0 4.9 ± 0.8 85 ± 17 -3.8
3.4.12.02. Thiostrepton 1e9w Streptomyces azureus Secreted 1 0 7.3 ± 1.5 86 ± 15 -4.9
3.4.10.01. Methanobactin 4oz7 Methylosinus sporium Secreted 1 0 2.5 ± 1.4 86 ± 15 -4.5
3.4.08.03. Oxytocin 1xy2 Bos taurus Secreted 1 0 2.1 ± 2.6 86 ± 12 -3.2
3.4.02.02. Mersacidin, structure in methanol solution 1mqx Bacillus sp. Secreted 1 0 1.9 ± 1.3 87 ± 15 -2.9
3.4.12.01. Actinomycin D 1a7y Streptomyces antibioticus Secreted 1 0 11.5 ± 0.9 89 ± 11 -12.2
3.4.04.03. Tridecaptin A1 2n5y Designed proteins Undefined 1 0 2.1 ± 1.0 89 ± 7 -3.9
3.4.06.01. Conomarphin 2jqc Conus marmoreus Secreted 1 0 4.1 ± 1.1 89 ± 12 -7.4
3.4.01.01. Contryphan-Lo 2m6h Conus loroisii Secreted 1 0 3.3 ± 0.8 89 ± 14 -5.4
3.4.02.02. Mersacidin, structure in DPC micelles 1mqy Bacillus sp. Secreted 1 0 5.3 ± 0.9 90 ± 12 -6.1
3.4.02.03. Nisin-Lipid II complex in DMSO solution 1wco Lactococcus lactis Secreted 1 0 8.1 ± 1.0 90 ± 5 -8.0
3.4.02.01. Actagardine, structure in acetonitrile solution 1aj1 Actinoplanes liguriae Secreted 1 0 3.0 ± 1.1 90 ± 11 -5.7